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https://www.readbyqxmd.com/read/29917320/efficacy-of-repeated-surgery-is-superior-to-that-of-non-surgery-for-recurrent-second-primary-lung-cancer-after-initial-operation-for-primary-lung-cancer
#1
Haitao Zhou, Xiaozheng Kang, Liang Dai, Wanpu Yan, Yongbo Yang, Yao Lin, Ke-Neng Chen
BACKGROUND: The current study aimed to determine the oncological efficacy and surgical safety of multiple pulmonary resections (MPRs) after prior curative surgery for local regional recurrent or second primary lung cancers. METHODS: All cases of lung cancer included in our prospective database between January 2000 and July 2015 were retrospectively reviewed. The oncological efficacy endpoints for synchronous and metachronous MPR were five-year overall survival (OS), disease-free survival (DFS), and progression-free survival (PFS) rates after the second surgery...
June 19, 2018: Thoracic Cancer
https://www.readbyqxmd.com/read/29916282/salivary-cytokine-panel-indicative-of-non-small-cell-lung-cancer
#2
Tomonobu Koizumi, Vivek Shetty, Masaki Yamaguchi
Objective To develop a combinatorial panel of salivary cytokines that manifests the presence of non-small cell lung cancer (NSCLC) that will eventually improve prognosis by facilitating the early diagnosis and management of this common cancer. Methods We performed a case-control study comparing salivary cytokine profiles of 35 adult subjects with NSCLC with those of 35 matched, healthy nonsmokers. Multiplex bead array assays were used to quantify 27 cytokines in saliva, serum, and oral mucosal transudate samples...
January 1, 2018: Journal of International Medical Research
https://www.readbyqxmd.com/read/29915974/managing-a-positive-air-leak-test-during-a-gastrojejunostomy-revision
#3
Dvir Froylich, Matthew Davis, Gautam Sharma, Tammy Fouse, Philip Schauer, Stacy Brethauer
BACKGROUND: Gastrojejunostomy revision after gastric bypass surgery is a challenging procedure that requires advanced skills. The air-leak test was performed to identify gastrojejunostomy leaks. Omental patch seal technique is a well-known treatment of perforated gastrojejunostomy ulcers (Surg Obes Relat Dis 4:423-8, 2012; Surg Endosc 2:384-9, 2013; Surg Endosc 11:2110, 2007). METHODS: We present a case of a 40-year-old female, who underwent laparoscopic gastric bypass 6 years prior and subsequently developed marginal ulcer, resulting in chronic gastrojejunostomy stricture...
June 18, 2018: Obesity Surgery
https://www.readbyqxmd.com/read/29915631/non-operative-management-of-type-2-ercp-related-retroperitoneal-duodenal-perforations-a-9-year-experience-from-a-single-center
#4
Vasileios Theopistos, Georgios Theocharis, Christos Konstantakis, Panagiotis Kitrou, Ioannis Kehagias, Christos Triantos, Konstantinos Thomopoulos
Background: No consensus exists on treatment of endoscopic retrograde cholangiopancreatography (ERCP) -related, retroperitoneal duodenal perforations. The aim of this study is to determine the incidence of post-ERCP retroperitoneal periampullary (type 2) duodenal perforations and the clinical outcome of non-surgical management. Methods: Patients who underwent ERCP in our institution during the period from January 1, 2009 to December 31, 2017 were included. Any cases of retroperitoneal periampullary duodenal (type 2) perforation were identified...
June 2018: Gastroenterology Research
https://www.readbyqxmd.com/read/29914487/blunt-liver-trauma-a-descriptive-analysis-from-a-level-i-trauma-center
#5
Ibrahim Afifi, Sheraz Abayazeed, Ayman El-Menyar, Husham Abdelrahman, Ruben Peralta, Hassan Al-Thani
BACKGROUND: We aimed to review liver injury experience in a level 1 trauma center; namely clinical presentation, grading, management approach and clinical outcomes. METHODS: It is a retrospective analysis to include all blunt liver injury patients who were admitted at the Level 1 trauma center over a 3-year period. Data were compared and analyzed based on the liver injury grades and management approaches. RESULTS: Blunt liver injury accounted for 38% of the total blunt abdominal trauma cases with a mean age of 31 ± 13 years...
June 19, 2018: BMC Surgery
https://www.readbyqxmd.com/read/29913711/some-practical-treatment-methods-of-dealing-with-pain-disabilities-in-rural-ghana
#6
Desmond Ayim-Aboagye, T Gordh
Background and aims The investigation was conducted among six practitioners and twenty-two patients in rural Ghana, where both practitioners and patients, were asked to unveil effective methods of treating pain and pain disabilities. Methods The investigation utilised strictly observational methods in acquiring data from two communities. Both patients and practitioners were later interviewed in a manner that elicited certain information needed to provide accurate understanding concerning these treatments methods they give to patients...
December 29, 2017: Scandinavian Journal of Pain
https://www.readbyqxmd.com/read/29909664/predicting-in-hospital-mortality-in-older-general-surgical-patients
#7
A Vilches-Moraga, J Fox, A Paracha, A Gomez-Quintanilla, J Epstein, L Pearce
Introduction A significant number of emergency general surgical admissions occur in older patients. Clinical decision making in this group is challenging and current risk prediction tools extrapolate data from cohorts of younger patients. This is the first UK study to examine risk factors predicting in-hospital mortality in older acute surgical patients undergoing comprehensive geriatric assessment. Methods This was a prospective study of consecutive patients aged ≥75 years admitted non-electively to general surgery wards between September 2014 and February 2017 who were reviewed by an elderly medicine in-reach service...
June 18, 2018: Annals of the Royal College of Surgeons of England
https://www.readbyqxmd.com/read/29909466/successful-non-operative-management-of-haemodynamically-unstable-traumatic-splenic-injuries-4-year-case-series-in-a-uk-major-trauma-centre
#8
Richard A Armstrong, Andrew Macallister, Benjamin Walton, Julian Thompson
PURPOSE: Management of traumatic splenic injury may be operative or non-operative (including embolization and conservative management). Traditionally, haemodynamic instability has been an indication for operative intervention. We aimed to report our experience of managing traumatic splenic injury at a regional major trauma centre in the UK over a 4-year period, with a particular focus on the non-operative management (NOM) of haemodynamically unstable patients. METHODS: All patients with splenic injuries admitted to North Bristol NHS Trust from April 2012 to March 2016 were included...
June 16, 2018: European Journal of Trauma and Emergency Surgery: Official Publication of the European Trauma Society
https://www.readbyqxmd.com/read/29907900/-anesthesia-ventilation-and-pain-treatment-in-thoracic-trauma
#9
REVIEW
M Weigeldt, M Paul, S Schulz-Drost, M D Schmittner
The management of anesthesia plays a central role in the treatment of thoracic trauma, both in the initial phase when safeguarding the difficult airway and in the intensive care unit. A rapid transfer to a trauma center should be considered in order to recognize and treat organ dysfunction in time. Development of atelectasis, pneumonia and acute lung failure are common pulmonary complications. Non-invasive ventilation combined with physiotherapy and respiratory training can help to minimize these pulmonary complications...
June 15, 2018: Der Unfallchirurg
https://www.readbyqxmd.com/read/29904819/perioperative-management-of-patients-with-addiction-to-opioid-and-non-opioid-medications
#10
REVIEW
Donna-Ann Thomas, Praba Boominathan, Jyotsna Goswami, Sudipta Mukherjee, Nalini Vadivelu
PURPOSE OF REVIEW: With the rise of the opioid epidemic, anesthesiologists will find themselves faced with opioid-addicted patients more frequently. Addiction to opioids may also occur concurrently with abuse of other non-opioid medications. Our review article seeks to outline an armamentarium of pain management strategies in the perioperative period for these patients with addiction to opioid and non-opioid medications. RECENT FINDINGS: Statistics from the CDC demonstrate a shocking increase in opioid prescription rates and opioid-related deaths...
June 14, 2018: Current Pain and Headache Reports
https://www.readbyqxmd.com/read/29904725/serum-level-of-interleukin-13-receptor-alpha-2-in-infants-with-biliary-atresia-is-it-of-value
#11
Nermin Adawy, Hanaa El-Araby, Alif Allam, Soha Elshenawy, Mohammed Khedr, Yasmine Ibrahim, Haidy M Zakaria
Aim of the study: We aimed to assess the utility of serum level IL-13Rα2 receptors as a non-invasive marker for early diagnosis of biliary atresia (BA) and selection of BA patients indicated for Kasai portoenterostomy. Material and methods: The study included 60 infants with neonatal cholestasis in three groups; early BA group ( n = 20), delayed BA group ( n = 20) and non-BA cholestasis group ( n = 20). A fourth group of 20 healthy neonates ( n = 20) served as controls...
June 2018: Clinical and Experimental Hepatology
https://www.readbyqxmd.com/read/29903511/non-inferiority-of-open-passive-drains-compared-with-closed-suction-drains-in-pancreatic-surgery-outcomes-a-prospective-observational-study
#12
Giovanni Marchegiani, Giampaolo Perri, Alessandra Pulvirenti, Elisabetta Sereni, Anna Maria Azzini, Giuseppe Malleo, Roberto Salvia, Claudio Bassi
BACKGROUND: Policies concerning the management of operatively placed drains after pancreatic surgery are still under debate. Open passive drains and closed-suction drains are both used currently in clinical practice worldwide, but there are no reliable data regarding potential differences in the postoperative outcomes associated with each drain type. The aim of the present study was to compare open passive drains and closed-suction drains with regard to postoperative contamination of the drainage fluid and overall morbidity and mortality...
June 11, 2018: Surgery
https://www.readbyqxmd.com/read/29903011/a-discrete-event-simulation-approach-for-reserving-capacity-for-emergency-patients-in-the-radiology-department
#13
Li Luo, Yumeng Zhang, Fang Qing, Hongwei Ding, Yingkang Shi, Huili Guo
BACKGROUND: Many hospitals in China experience large volumes of emergency department (ED) radiology patients, thereby lengthening the wait times for non-emergency radiology patients. We examine whether an emergency reservation policy which deals with stochastic arrivals of ED patients can shorten wait times, and what effect it has on patient and hospital related metrics. METHODS: In this study, operations research models are used to develop an emergency reservation policy...
June 15, 2018: BMC Health Services Research
https://www.readbyqxmd.com/read/29902932/external-snapping-hip-a-systematic-review-of-outcomes-following-surgical-intervention-external-snapping-hip-systematic-review
#14
Todd P Pierce, Jennifer Kurowicki, Kimona Issa, Antony Festa, Anthony J Scillia, Vincent K McInerney
PURPOSE: To evaluate the outcomes of surgical management for external snapping hip in terms of: (1) recurrence; (2) complications; and (3) return to pre-injury activities. METHODS: A thorough review of 4 electronic databases- EMBASE, CINAHL Plus, PubMed, and Scopus was performed to find all relevant studies for this review that were published between January 2000 and January 2017 that addressed surgical treatment for external snapping hip. The following reports were excluded: (1) non-English manuscripts; (2) n ⩽ 5; (3) clinical reviews; (4) surgical technique notes; (5) studies only analysing diagnosis; and (6) nonoperative management studies...
June 1, 2018: Hip International: the Journal of Clinical and Experimental Research on Hip Pathology and Therapy
https://www.readbyqxmd.com/read/29902567/pre-and-post-surgery-mrsi-predictive-value-in-adult-oligodendroglioma-prognosis
#15
Caroline Bund, François Lefebvre, Roland Schott, Marie-Pierre Chenard, Benoît Lhermitte, Hélène Cebula, Stéphane Kremer, François Proust, Izzie-Jacques Namer
PURPOSE: The aim of this study was to study the relationship between MRSI, before and after surgery, and patient survival. The accuracy of pre-operative MRSI in differentiating low- from high-grade oligodendrogliomas (ODGs) was also studied. METHODS: Two hundred patients with ODG were retrospectively included in this study between 2000 and 2016. All patients underwent MRSI before any treatment or biopsy and/or after surgery for an intra-axial brain tumour. The R software was used for statistical data analysis...
June 11, 2018: Magnetic Resonance Imaging
https://www.readbyqxmd.com/read/29901722/genitourinary-surgical-workload-at-deployed-u-s-facilities-in-iraq-and-afghanistan-2002-2016
#16
Caryn A Turner, Jean A Orman, Zsolt T Stockinger, Steven J Hudak
Introduction: Genitourinary surgery constitutes approximately 1.15% of procedures performed for combat injuries. During forward deployment, surgeons usually deploy without urology support. To better understand the training and skills maintenance needs for genitourinary procedures by describing in detail the genitourinary surgical workload during 15 years of combat operations and compare our findings with those from previously published articles. Material and Methods: A retrospective analysis of the Department of Defense Trauma Registry (DoDTR) was performed for all Roles 2 and 3 medical treatment facilities in Iraq and Afghanistan, from January 2002 to May 2016...
June 13, 2018: Military Medicine
https://www.readbyqxmd.com/read/29901544/limits-of-intravascular-contrast-extravasation-on-computed-tomography-scan-to-define-the-need-for-pelvic-angioembolization-in-pelvic-blunt-trauma-a-specific-assessment-on-the-risk-of-false-positives
#17
Séverin Ramin, Margaux Hermida, Ingrid Millet, Thibault Murez, Valérie Monnin, Mazen Hamoui, Xavier Capdevila, Jonathan Charbit
BACKROUND: The objective was to assess the predictive performance of different intravascular contrast extravasation (ICE) characteristics for need for pelvic transarterial embolization (TAE) to determine the risk factors of false-positives. METHODS: A retrospective study was performed in our trauma center between 2010 and 2015. All severe trauma patients with pelvic fracture were included. Pelvic ICE characteristics on computed tomography (CT) scan were studied: arterial (aSICE), portal surface (pSICE), and extension (exSICE) anatomic relationships...
June 12, 2018: Journal of Trauma and Acute Care Surgery
https://www.readbyqxmd.com/read/29901543/early-arterial-access-for-reboa-is-related-to-survival-outcome-in-trauma
#18
Yosuke Matsumura, Junichi Matsumoto, Hiroshi Kondo, Koji Idoguchi, Tokiya Ishida, Yohei Okada, Yuri Kon, Kazuyuki Oka, Kenichiro Ishida, Yukitoshi Toyoda, Tomohiro Funabiki
INTRODUCTION: Resuscitative endovascular balloon occlusion of the aorta (REBOA) has been employed in refractory hemorrhagic shock patients. Since the optimal timing of arterial access remains unclear, we evaluated the pre-occlusion status of patients and elapsed time from the arrival to the hospital are associated with the survival outcomes in the REBOA patients. METHODS: From August 2011-December 2016, The DIRECT-IABO investigators registered refractory hemorrhagic shock patients undergoing REBOA from 23 hospitals in Japan...
June 12, 2018: Journal of Trauma and Acute Care Surgery
https://www.readbyqxmd.com/read/29901537/an-evidence-based-approach-to-the-management-of-children-with-morquio-a-syndrome-presenting-with-craniocervical-pathology
#19
Nicole Williams, Alessandro Narducci, Deborah M Eastwood, Maureen Cleary, Dominic Thompson
STUDY DESIGN: Retrospective case series OBJECTIVE.: To review clinical and radiological outcomes of craniovertebral surgery in children with Morquio A syndrome (Mucopolysaccharidosis type IVA) and develop an evidence-based management algorithm. SUMMARY OF BACKGROUND DATA: Myelopathy secondary to craniovertebral pathology is a common cause of neurological disability in Morquio A syndrome. Previously unresolved surgical controversies include the value of surveillance, surgical indications and operative technique...
June 12, 2018: Spine
https://www.readbyqxmd.com/read/29901389/3-4-dihydroxyphenylethanol-assuages-cognitive-impulsivity-in-alzheimer-s-disease-by-attuning-hpa-axis-via-differential-crosstalk-of-%C3%AE-7-nachr-with-microrna-124-and-hdac6
#20
ArunSundar MohanaSundaram, Thukani Sathanantham Shanmugarajan, Velayutham Ravichandiran
Cognitive impulsivity, a form of suboptimal cost-benefit decision making is an illustrious attribute of an array of neurodegenerative diseases including Alzheimer's Disease (AD). In this study, delay discounting paradigm was used to assess the effect of 3,4-dihydroxyphenylethanol (DOPET) on cognitive impulsivity-in an oA42i (oligomeric amyloid β1-42 plus ibotenic acid) induced AD mouse model-using a non-spatial T-maze task. The results depicted that oA42i administration elevated cognitive impulsivity, whereas DOPET treatment attenuated the impulsive behavior and matched the choice of the sham-operated controls...
June 14, 2018: ACS Chemical Neuroscience
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