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https://www.readbyqxmd.com/read/29333611/cognitive-dysfunction-after-generalized-tonic-clonic-status-epilepticus-in-adults
#1
K N Power, A Gramstad, N E Gilhus, K O Hufthammer, B A Engelsen
OBJECTIVES: Generalized tonic-clonic status epilepticus (GTC-SE) is considered a risk for cognitive impairment. Research with standardized tools is scarce and non-conclusive. We systematically assessed short-term and long-term cognitive function after GTC-SE. MATERIALS AND METHODS: Thirty-three patients were tested after the clinical post-ictal phase of GTC-SE (timepoint 1) and again after 1 year (timepoint 2). Twenty controls were examined with the same tests...
January 14, 2018: Acta Neurologica Scandinavica
https://www.readbyqxmd.com/read/29332179/profiles-and-correlates-of-parent-child-agreement-on-social-anxiety-symptoms-in-youth-with-autism-spectrum-disorder
#2
Catherine A Burrows, Lauren V Usher, Emily M Becker-Haimes, Camilla M McMahon, Peter C Mundy, Amanda Jensen-Doss, Heather A Henderson
This study characterized patterns and correlates of parent-youth agreement on social anxiety in youth with and without autism spectrum disorder (ASD). Participants (279 verbally-fluent youth aged 8-16 years, NASD = 144, NTD = 135) completed the SASC-R. Youth with ASD exhibited higher social anxiety across informants. While TD youth endorsed higher anxiety than did parents, self- and parent-reports did not differ in youth with ASD. For children with ASD, higher parent-youth agreement was associated with lower lifetime ASD symptoms and higher adaptive skills...
January 13, 2018: Journal of Autism and Developmental Disorders
https://www.readbyqxmd.com/read/29331837/spontaneous-focusing-on-numerosity-in-preschool-as-a-predictor-of-mathematical-skills-and-knowledge-in-the-fifth-grade
#3
Cristina E Nanu, Jake McMullen, Petriina Munck, Minna M Hannula-Sormunen
Previous studies in a variety of countries have shown that there are substantial individual differences in children's spontaneous focusing on numerosity (SFON), and these differences are positively related to the development of early numerical skills in preschool and primary school. A total of 74 5-year-olds participated in a 7-year follow-up study, in which we explored whether SFON measured with very small numerosities at 5 years of age predicts mathematical skills and knowledge, math motivation, and reading in fifth grade at 11 years of age...
January 11, 2018: Journal of Experimental Child Psychology
https://www.readbyqxmd.com/read/29331153/is-cognitive-impairment-associated-with-antipsychotic-dose-and-anticholinergic-equivalent-loads-in-first-episode-psychosis
#4
Alejandro Ballesteros, Ana M Sánchez-Torres, Jose M López-Ilundain, Bibiana Cabrera, Antonio Lobo, Ana M González-Pinto, Covadonga Díaz-Caneja, Iluminada Corripio, Eduard Vieta, Elena de la Serna, Julio Bobes, Judith Usall, Fernando Contreras, Ruth Lorente-Omeñaca, Gisela Mezquida, Miguel Bernardo, Manuel J Cuesta
BACKGROUND: Cognitive deficits are a core feature of early stages in schizophrenia. However, the extent to which antipsychotic (AP) have a deleterious effect on cognitive performance remains under debate. We aim to investigate whether anticholinergic loadings and dose of AP drugs in first episode of psychosis (FEP) in advanced phase of remission are associated with cognitive impairment and the differences between premorbid intellectual quotient (IQ) subgroups. METHODS: Two hundred and sixty-six patients participated...
January 14, 2018: Psychological Medicine
https://www.readbyqxmd.com/read/29330315/outcome-of-preterm-infants-with-postnatal-cytomegalovirus-infection
#5
Julia Gunkel, Linda S de Vries, Marian Jongmans, Corine Koopman-Esseboom, Ingrid C van Haastert, Maria C J Eijsermans, Carolien van Stam, Bert G A van Zanten, Tom F W Wolfs, Joppe Nijman
OBJECTIVES: To assess whether preterm infants with postnatal cytomegalovirus infection develop neurologic sequelae in early childhood. METHODS: Infants <32 weeks' gestation were prospectively screened for cytomegalovirus (CMV) at term-equivalent age. Neurodevelopment was compared between CMV-positive and CMV-negative infants by using the Griffiths Mental Development Scales (GMDS) at 16 months' corrected age (CA); the Bayley Scales of Infant and Toddler Development, Third Edition or the GMDS at 24 to 30 months' CA; and the Wechsler Preschool and Primary Scale of Intelligence, Third Edition and Movement Assessment Battery for Children, Second Edition at 6 years of age...
January 12, 2018: Pediatrics
https://www.readbyqxmd.com/read/29330314/developmental-disability-at-school-age-and-difficulty-obtaining-follow-up-data
#6
Lex W Doyle, Peter J Anderson, Alice Burnett, Catherine Callanan, Marion McDonald, Marie Hayes, Gillian Opie, Elizabeth Carse, Jeanie L Y Cheong
BACKGROUND: The relationship of developmental disability rates with difficulty obtaining follow-up data is unclear. With this study, we aimed to determine if children who attended research follow-up assessments with more difficulty had more disability at school age, compared with those who attended with less difficulty, and to establish the relationship between follow-up and disability rates. METHODS: Two groups, comprising 219 consecutive survivors born at <28 weeks' gestation or at <1000 g birth weight in the state of Victoria, Australia, in 2005, and 218 term-born, normal birth weight controls were assessed at 8 years of age for neurodevelopmental disability (any of IQ <-1 SD, cerebral palsy, blindness, or deafness)...
January 12, 2018: Pediatrics
https://www.readbyqxmd.com/read/29328299/coherent-modulation-up-to-100-gbd-16qam-using-silicon-organic-hybrid-soh-devices
#7
S Wolf, H Zwickel, C Kieninger, M Lauermann, W Hartmann, Y Kutuvantavida, W Freude, S Randel, C Koos
We demonstrate the generation of higher-order modulation formats using silicon-based inphase/quadrature (IQ) modulators at symbol rates of up to 100 GBd. Our devices exploit the advantages of silicon-organic hybrid (SOH) integration, which combines silicon-on-insulator waveguides with highly efficient organic electro-optic (EO) cladding materials to enable small drive voltages and sub-millimeter device lengths. In our experiments, we use an SOH IQ modulator with a π-voltage of 1.6 V to generate 100 GBd 16QAM signals...
January 8, 2018: Optics Express
https://www.readbyqxmd.com/read/29327328/genetic-analysis-of-very-obese-children-with-autism-spectrum-disorder
#8
Herman D Cortes, Rachel Wevrick
Autism spectrum disorder (ASD) is defined by the triad of deficits in social interactions, deficits in communication, and repetitive behaviors. Common co-morbidities in syndromic forms of ASD include intellectual disability, seizures, and obesity. We asked whether very obese children with ASD had different behavioral, physical and genetic characteristics compared to children with ASD who were not obese. We found that very obese children with ASD had significantly poorer scores on standardized behavioral tests...
January 11, 2018: Molecular Genetics and Genomics: MGG
https://www.readbyqxmd.com/read/29327252/compared-vulnerabilities-to-small-cardiac-motions-between-different-cameras-used-for-myocardial-perfusion-imaging
#9
Julien Salvadori, Yolande Petegnief, Remi Sabbah, Olivier Morel, Hatem Boulahdour, Gilles Karcher, Pierre-Yves Marie, Laetitia Imbert
This phantom-based study was aimed to determine whether cardiac CZT-cameras, which provide an enhanced spatial resolution and image contrast compared to Anger cameras, are similarly affected by small cardiac motions. Translations of a left ventricular (LV) insert at half-SPECT acquisitions through six possible orthogonal directions and with 5- or 10-mm amplitude were simulated on the Discovery NM-530c and DSPECT CZT-cameras and on an Anger Symbia T2 camera equipped with an astigmatic (IQ.SPECT) or conventional parallel-hole collimator (Conv...
January 11, 2018: Journal of Nuclear Cardiology: Official Publication of the American Society of Nuclear Cardiology
https://www.readbyqxmd.com/read/29325045/mean-high-dose-l-thyroxine-treatment-is-efficient-and-safe-to-achieve-a-normal-iq-in-young-adult-patients-with-congenital-hypothyroidism
#10
Paulina Aleksander, Michaela Brückner-Spieler, Anne-Marie Stöhr, Erwin Lankes, Peter Kühnen, Dirk Schnabel, Andrea Ernert, Walter Stäblein, Maria E Craig, Oliver Blankenstein, Annette Grüters, Heiko Krude
Context: The optimal levothyroxine (LT4) dose required to treat congenital hypothyroidism (CH) remains unclear, with a debate if higher starting doses (>10µg/kg) are necessary and safe for normal Intelligence Quotient (IQ). Objective: To examine the psychomotor, metabolic and quality of life outcome in patients with CH treated with a mean high initial LT4 dose. Design, settings, participants: A cross- sectional cohort study of CH patients identified in the Berlin newborn screening programme from 1979-2003...
January 9, 2018: Journal of Clinical Endocrinology and Metabolism
https://www.readbyqxmd.com/read/29324759/disease-burden-of-methylmercury-in-the-german-birth-cohort-2014
#11
Julia Lackner, Michael Weiss, Christine Müller-Graf, Matthias Greiner
This study aimed to estimate the disease burden of methylmercury for children born in Germany in the year 2014. Humans are mainly exposed to methylmercury when they eat fish or seafood. Prenatal methylmercury exposure is associated with IQ loss. To quantify this disease burden, we used Monte Carlo simulation to estimate the incidence of mild and severe mental retardation in children born to mothers who consume fish based on empirical data. Subsequently, we calculated the disease burden with the disability-adjusted life years (DALY)-method...
2018: PloS One
https://www.readbyqxmd.com/read/29324299/boys-with-conduct-problems-and-callous-unemotional-traits-neural-response-to-reward-and-punishment-and-associations-with-treatment-response
#12
Amy L Byrd, Samuel W Hawes, Jeffrey D Burke, Rolf Loeber, Dustin A Pardini
Abnormalities in reward and punishment processing are implicated in the development of conduct problems (CP), particularly among youth with callous-unemotional (CU) traits. However, no studies have examined whether CP children with high versus low CU traits exhibit differences in the neural response to reward and punishment. A clinic-referred sample of CP boys with high versus low CU traits (ages 8-11; n = 37) and healthy controls (HC; n = 27) completed a fMRI task assessing reward and punishment processing...
December 15, 2017: Developmental Cognitive Neuroscience
https://www.readbyqxmd.com/read/29324267/clinical-validity-of-the-japanese-version-of-wais-iii-short-forms-adaptation-for-patients-with-mild-neurocognitive-disorder-and-dementia
#13
Mihoko Takeda, Makoto Nakaya, Yoko Kikuchi, Sayaka Inoue, Tomoyuki Kamata
We investigated the Japanese WAIS-III short form utility in mild neurocognitive disorder and dementia. Our sample consisted of 108 old patients (ages: 65-89; mean age = 78.3). Fifteen short forms (SFs) and full-scale (FS) IQs were compared. The SFs included Dyads (SF1, SF2), Triads (SF3), Tetrads (SF4, SF5, SF6, SF7), Pentad (SF8), Six-subtest (SF9), Seven-subtests (SF10(a)(b), SF11(a)(b), SF12), and Nine-subtest (SF13). Correlations between SFIQs and FSIQ were all significant. Significant differences also were found in paired t-test between FSIQ and 5 SFIQs (SF2: t = -4...
December 29, 2017: Asian Journal of Psychiatry
https://www.readbyqxmd.com/read/29322860/antenatal-and-neonatal-antecedents-of-executive-dysfunctions-in-extremely-preterm-children
#14
Alan Leviton, Robert M Joseph, Elizabeth N Allred, T Michael O'Shea, H Gerry Taylor, Karl K C Kuban
To find out why children born extremely preterm are at heightened risk of executive dysfunctions, the authors assessed 716 children who were 10 years old born extremely preterm whose IQ was ≥ 70. A working memory dysfunction (n = 169), an inhibition dysfunction (n = 360), a switching dysfunction (355), and all 3 (executive dysfunction; n = 107) were defined on the basis of Z-scores ≤ -1 on the Differential Ability Scales-II Working Memory composite, and/or on the NEPSY-II Inhibition-Inhibition and Inhibition-Switching subtests...
January 1, 2018: Journal of Child Neurology
https://www.readbyqxmd.com/read/29322239/the-lateralized-arcuate-fasciculus-in-developmental-pitch-disorders-among-mandarin-amusics-left-for-speech-and-right-for-music
#15
Xizhuo Chen, Yanxin Zhao, Suyu Zhong, Zaixu Cui, Jiaqi Li, Gaolang Gong, Qi Dong, Yun Nan
The arcuate fasciculus (AF) is a neural fiber tract that is critical to speech and music development. Although the predominant role of the left AF in speech development is relatively clear, how the AF engages in music development is not understood. Congenital amusia is a special neurodevelopmental condition, which not only affects musical pitch but also speech tone processing. Using diffusion tensor tractography, we aimed at understanding the role of AF in music and speech processing by examining the neural connectivity characteristics of the bilateral AF among thirty Mandarin amusics...
January 10, 2018: Brain Structure & Function
https://www.readbyqxmd.com/read/29321232/hypermyelination-of-the-left-auditory-cortex-in-developmental-dyslexia
#16
Michael A Skeide, Pierre-Louis Bazin, Robert Trampel, Andreas Schäfer, Claudia Männel, Katharina von Kriegstein, Angela D Friederici
OBJECTIVE: Cortical malformations are documented postmortem in speech processing areas of the dyslexic human brain. The goal of this pilot study was to find out if such anatomic anomalies can be detected noninvasively and in vivo. METHODS: We developed a reconstruction of left perisylvian cortex profiles at a resolution of 400 μm using T1 data acquired with ultra-high-field MRI at 7T. Cortical thickness, myelinated cortical thickness, and layer-wise myelination were then compared in 6 men with developmental dyslexia and 6 healthy controls matched for age, sex, handedness, education level, and nonverbal IQ...
January 10, 2018: Neurology
https://www.readbyqxmd.com/read/29314150/role-of-intelligence-quotient-iq-on-anxiety-and-behavior-in-children-with-hearing-and-speech-impairment
#17
Raghavendra M Shetty, Aditi Pashine, Nijo A Jose, Somasundar Mantha
AIM: To assess and compare the role of IQ on anxiety and behavior of children with and without hearing and speech impairment. MATERIAL AND METHODS: A total of 120 children of age group 7-14 years were included in the study, of which control group comprised of 60 normal healthy children and 60 hearing and speech impaired children formed the study group. The study was done in two consecutive sessions. First appointment for Culture Fair Intelligence Test and second appointment for RMS pictorial anxiety score (RMS-PS) and Frankl behavior rating which were assessed during oral prophylaxis...
January 4, 2018: Special Care in Dentistry
https://www.readbyqxmd.com/read/29309294/speed-of-language-comprehension-at-18-months-old-predicts-school-relevant-outcomes-at-54-months-old-in-children-born-preterm
#18
Virginia A Marchman, Elizabeth C Loi, Katherine A Adams, Melanie Ashland, Anne Fernald, Heidi M Feldman
OBJECTIVE: Identifying which preterm (PT) children are at increased risk of language and learning differences increases opportunities for participation in interventions that improve outcomes. Speed in spoken language comprehension at early stages of language development requires information processing skills that may form the foundation for later language and school-relevant skills. In children born full-term, speed of comprehending words in an eye-tracking task at 2 years old predicted language and nonverbal cognition at 8 years old...
January 3, 2018: Journal of Developmental and Behavioral Pediatrics: JDBP
https://www.readbyqxmd.com/read/29308773/evaluation-of-visual-outcomes-after-toric-intraocular-lens-implantation
#19
H R Ng, C H Goh, Y S Ngim, J Juliana
PURPOSE: To evaluate postoperative visual acuity, refractive status and rotational stability of toric intraocular lens (IOL) in correcting pre-existing corneal astigmatism. METHODS: A total of 69 patients with topographic corneal astigmatism of 1.0 Diopter (D) and above who underwent cataract surgery between June 2015 and December 2016 were included in this retrospective observational study. All preoperative toric IOL calculations were performed using immersion biometry...
December 2017: Medical Journal of Malaysia
https://www.readbyqxmd.com/read/29305746/verbal-and-nonverbal-anticipatory-mechanisms-in-bilinguals
#20
Lorenzo Desideri, Paola Bonifacci
Empirical evidence collected so far has revealed that the bilingual advantage cannot be reduced to a single component of the executive functioning, and point to the need to understand the effects of bilingual experience on cognition as influencing a wider family of mental processes, including, but not limited to, cognitive control. The present study aims to explore a relatively underinvestigated domain of bilingual cognitive processes, namely anticipation, through a series of different paradigms tapping proactive and reactive mechanisms at different levels of cognitive complexity and linguistic components...
January 5, 2018: Journal of Psycholinguistic Research
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