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https://www.readbyqxmd.com/read/29040919/functional-analyses-of-the-interaction-of-chicken-interleukin-23-subunit-p19-with-il-12-subunit-p40-to-form-the-il-23-complex
#1
Anh Duc Truong, Cong Thanh Hoang, Yeojin Hong, Janggeun Lee, Kyungbaek Lee, Hyun S Lillehoj, Yeong Ho Hong
This study represents the first description of the cloning of chicken IL-23p19 (ChIL-23α) and the function of the IL-23 complex in birds. Multiple alignment of ChIL-23α with other known IL-23α amino acid sequences revealed regions of amino acid conservation. The homologies of ChIL-23α, IL-12p35, and similar mammalian subunits ranged between 26% and 42%. ChIL-23α consisted of four exons and three introns; similar to those in humans and mice, and limited conservation of synteny between the human and chicken genomes was observed...
October 14, 2017: Molecular Immunology
https://www.readbyqxmd.com/read/29040873/hazard-perception-skills-of-young-drivers-with-attention-deficit-hyperactivity-disorder-adhd-can-be-improved-with-computer-based-driver-training-an-exploratory-randomised-controlled-trial
#2
C R Bruce, C A Unsworth, M P Dillon, R Tay, T Falkmer, P Bird, L M Carey
BACKGROUND: Young drivers with Attention Deficit Hyperactivity Disorder (ADHD) are at higher risk of road traffic injuries than their peers. Increased risk correlates with poor hazard perception skill. Few studies have investigated hazard perception training using computer technology with this group of drivers. OBJECTIVES: *Determine the presence and magnitude of the between-group and within- subject change in hazard perception skills in young drivers with ADHD who receive Drive Smart training...
October 14, 2017: Accident; Analysis and Prevention
https://www.readbyqxmd.com/read/29040206/the-life-saving-effect-of-adenosine-lidocaine-and-magnesium-cocktail-during-hypovolemic-shock-one-stone-three-birds
#3
Lusha Xiang, Harold G Klemcke, Kathy L Ryan
No abstract text is available yet for this article.
October 16, 2017: Journal of Trauma and Acute Care Surgery
https://www.readbyqxmd.com/read/29036923/environmental-impact-and-relative-invasiveness-of-free-roaming-domestic-carnivores-a-north-american-survey-of-governmental-agencies
#4
Ana Lepe, Valerie Kaplan, Alirio Arreaza, Robert Szpanderfer, David Bristol, M Scott Sinclair
A survey of the United States and Canadian governmental agencies investigated the environmental impact and relative invasiveness of free-roaming domestic non-native carnivores-dogs, cats, and ferrets. Agencies represented wildlife, fish, game, natural or environmental resources, parks and recreation, veterinary and human health, animal control, and agriculture. Respondents were asked to document the number and frequency of sightings of unconfined animals, evidence for environmental harm, and the resulting "degree of concern" in their respective jurisdictions...
October 14, 2017: Animals: An Open Access Journal From MDPI
https://www.readbyqxmd.com/read/29036832/neuropathological-comparison-of-adult-onset-and-juvenile-huntington-s-disease-with-cerebellar-atrophy-a-report-of%C3%A2-a%C3%A2-father-and-son
#5
Caitlin S Latimer, Margaret E Flanagan, Patrick J Cimino, Suman Jayadev, Marie Davis, Zachary S Hoffer, Thomas J Montine, Luis F Gonzalez-Cuyar, Thomas D Bird, C Dirk Keene
BACKGROUND: Huntington's disease (HD) is an autosomal dominant neurodegenerative disease caused by a trinucleotide (CAG) repeat expansion in huntingtin (HTT) on chromosome 4. Anticipation can cause longer repeat expansions in children of HD patients. Juvenile Huntington's disease (JHD), defined as HD arising before age 20, accounts for 5-10% of HD cases, with cases arising in the first decade accounting for approximately 1%. Clinically, JHD differs from the predominately choreiform adult onset Huntington's disease (AOHD) with variable presentations, including symptoms such as myoclonus, seizures, Parkinsonism, and cognitive decline...
October 11, 2017: Journal of Huntington's Disease
https://www.readbyqxmd.com/read/29036352/environmental-plasticity-in-the-intersexual-correlation-and-sex-bias-of-gene-expression
#6
Changde Cheng, Mark Kirkpatrick
Intersexual genetic correlations are expected to constrain the evolution of sexual dimorphic traits, including the degree of sex-biased gene expression. Consistent with that expectation, studies in fruit flies and birds have reported that genes whose expression has a strong intersexual genetic correlation (rMF) show a lower level of sex-biased expression (SBE). However, it is known that both rMF and SBE can be affected by the environment. It is therefore unclear whether there is a consistent relationship between these two quantities across multiple environments...
September 27, 2017: Journal of Heredity
https://www.readbyqxmd.com/read/29035754/regulation-of-autophagy-factors-by-oxidative-stress-and-cardiac-enzymes-imbalance-during-arsenic-or-and-copper-induced-cardiotoxicity-in-gallus-gallus
#7
Siwen Li, Hongjing Zhao, Yu Wang, Yizhi Shao, Bangyi Wang, Yulong Wang, Mingwei Xing
Basal autophagy has an indispensable role in the functioning and maintenance of cardiac geometry under physiological conditions. Recently, increasing evidence has demonstrated that arsenic (As)/copper (Cu) play important roles in the autophagy of the heart. The current study was to evaluate whether oxidative damage by As or/and Cu was correlated with autophagy through the phosphatidylinositol 3-kinase (PI3K)/protein kinase B (AKT)/mammalian target of rapamycin (mTOR) pathway in the heart of birds. Arsenic trioxide (30mg/kg) or/and cupric sulfate (300mg/kg) were administered in a basal diet to male Hy-line chickens (one-day-old) for 12 weeks...
October 13, 2017: Ecotoxicology and Environmental Safety
https://www.readbyqxmd.com/read/29035663/contrast-fluoroscopic-evaluation-of-gastrointestinal-transit-times-with-and-without-the-use-of-falconry-hoods-in-red-tailed-hawks-buteo-jamaicensis
#8
Grayson A Doss, Jackie M Williams, Christoph Mans
OBJECTIVE To evaluate gastrointestinal transit times in red-tailed hawks (Buteo jamaicensis) by use of contrast fluoroscopic imaging and investigate the effect of falconry hooding in these hawks on gastrointestinal transit time. DESIGN Prospective, randomized, blinded, complete crossover study. ANIMALS 9 healthy red-tailed hawks. PROCEDURES Hawks were gavage-fed a 30% weight-by-volume barium suspension (25 mL/kg [11.3 mL/lb]) into the crop. Fluoroscopic images were obtained at multiple time points after barium administration...
November 1, 2017: Journal of the American Veterinary Medical Association
https://www.readbyqxmd.com/read/29035625/chickens-with-humanized-immunoglobulin-genes-generate-antibodies-with-high-affinity-and-broad-epitope-coverage-to-conserved-targets
#9
Kathryn H Ching, Ellen J Collarini, Yasmina N Abdiche, Daniel Bedinger, Darlene Pedersen, Shelley Izquierdo, Rian Harriman, Lei Zhu, Robert J Etches, Marie-Cecile van de Lavoir, William D Harriman, Philip A Leighton
Transgenic animal platforms for the discovery of human monoclonal antibodies have been developed in mice, rats, rabbits and cows. The immune response to human proteins is limited in these animals by their tolerance to mammalian-conserved epitopes. To expand the range of epitopes that are accessible, we have chosen an animal host that is less phylogenetically related to humans. Specifically, we generated transgenic chickens expressing antibodies from immunoglobulin heavy and light chain loci containing human variable regions and chicken constant regions...
October 16, 2017: MAbs
https://www.readbyqxmd.com/read/29035135/draft-de-novo-genome-sequence-of-agapornis-roseicollis-for-application-in-avian-breeding
#10
Henriëtte van der Zwan, Francois van der Westhuizen, Carina Visser, Rencia van der Sluis
In aviculture, lovebirds are considered one of the most popular birds to keep. This African parakeet is known for its range of plumage colors and ease to tame. Plumage variation is the most important price-determining trait of these birds, and also the main selection criterion for breeders. Currently, no genetic screening tests for traits of economic importance or to confirm pedigree data are available for any of the nine lovebird species. As a starting point to develop these tests, the de novo genome of Agapornis roseicollis (rosy-faced lovebird) was sequenced, assembled, and annotated...
October 16, 2017: Animal Biotechnology
https://www.readbyqxmd.com/read/29035021/microbial-communities-and-organic-biomarkers-in-a-proterozoic-analog-sinkhole
#11
T L Hamilton, P V Welander, H L Albrecht, J M Fulton, I Schaperdoth, L R Bird, R E Summons, K H Freeman, J L Macalady
Little Salt Spring (Sarasota County, FL, USA) is a sinkhole with groundwater vents at ~77 m depth. The entire water column experiences sulfidic (~50 μM) conditions seasonally, resulting in a system poised between oxic and sulfidic conditions. Red pinnacle mats occupy the sediment-water interface in the sunlit upper basin of the sinkhole, and yielded 16S rRNA gene clones affiliated with Cyanobacteria, Chlorobi, and sulfate-reducing clades of Deltaproteobacteria. Nine bacteriochlorophyll e homologues and isorenieratene indicate contributions from Chlorobi, and abundant chlorophyll a and pheophytin a are consistent with the presence of Cyanobacteria...
November 2017: Geobiology
https://www.readbyqxmd.com/read/29034530/gene-expression-and-morphological-changes-in-the-intestinal-mucosa-associated-with-increased-permeability-induced-by-short-term-fasting-in-chickens
#12
S Gilani, G S Howarth, G Nattrass, S M Kitessa, R Barekatain, R E A Forder, C D Tran, R J Hughes
Short-term fasting for 4.5 and 9 hr has been demonstrated to increase intestinal permeability (IP) in chickens. This study aimed to investigate the effects of 0, 4.5, 9 and 19.5 hr fasting on intestinal gene expression and villus-crypt architecture of enterocytes in jejunal and ileal samples. On day 38, Ross-308 male birds were fasted according to their group and then euthanised. Two separate intestinal sections (each 2 cm long, jejunum and ileum) were collected. One section was utilised for villus height and crypt depth measurements...
October 16, 2017: Journal of Animal Physiology and Animal Nutrition
https://www.readbyqxmd.com/read/29034326/bacterial-lipopolysaccharide-destabilizes-influenza-viruses
#13
Christopher Bandoro, Jonathan A Runstadler
Depending on the specific viral pathogen, commensal bacteria can promote or reduce the severity of viral infection and disease progression in their hosts. Influenza A virus (IAV) has a broad host range, comprises many subtypes, and utilizes different routes of transmission, including the fecal-oral route in wild birds. It has been previously demonstrated that commensal bacteria can interact with the host's immune system to protect against IAV pathogenesis. However, it is unclear whether bacteria and their products may be interacting directly with IAV to impact virion stability...
September 2017: MSphere
https://www.readbyqxmd.com/read/29033455/genetic-variation-birds-of-a-feather-genetic-mapping-of-yellow-pigmentation
#14
Ross Cloney
No abstract text is available yet for this article.
October 16, 2017: Nature Reviews. Genetics
https://www.readbyqxmd.com/read/29033264/editor-s-note
#15
EDITORIAL
Chloe E Bird
No abstract text is available yet for this article.
October 12, 2017: Women's Health Issues: Official Publication of the Jacobs Institute of Women's Health
https://www.readbyqxmd.com/read/29032907/pharmaceuticals-in-water-fish-and-osprey-nestlings-in-delaware-river-and-bay
#16
Thomas G Bean, Barnett A Rattner, Rebecca S Lazarus, Daniel D Day, S Rebekah Burket, Bryan W Brooks, Samuel P Haddad, William W Bowerman
Exposure of wildlife to Active Pharmaceutical Ingredients (APIs) is likely to occur but studies of risk are limited. One exposure pathway that has received attention is trophic transfer of APIs in a water-fish-osprey food chain. Samples of water, fish plasma and osprey plasma were collected from Delaware River and Bay, and analyzed for 21 APIs. Only 2 of 21 analytes exceeded method detection limits in osprey plasma (acetaminophen and diclofenac) with plasma levels typically 2-3 orders of magnitude below human therapeutic concentrations (HTC)...
October 9, 2017: Environmental Pollution
https://www.readbyqxmd.com/read/29032087/are-we-really-measuring-empathy-proposal-for-a-new-measurement-framework
#17
REVIEW
Michel-Pierre Coll, Essi Viding, Markus Rütgen, Giorgia Silani, Claus Lamm, Caroline Catmur, Geoffrey Bird
Empathy - currently defined as the sharing of another's affective state - has been the focus of much psychological and neuroscientific research in the last decade, much of which has been focused on ascertaining the empathic ability of individuals with various clinical conditions. However, most of this work tends to overlook the fact that empathy is the result of a complex process requiring a number of intermediate processing steps. It is therefore the case that describing an individual or group as 'lacking empathy' lacks specificity...
October 13, 2017: Neuroscience and Biobehavioral Reviews
https://www.readbyqxmd.com/read/29031813/song-practice-as-a-rewarding-form-of-play-in-songbirds
#18
REVIEW
Lauren V Riters, Jeremy A Spool, Devin P Merullo, Allison H Hahn
In adult songbirds, the primary functions of song are mate attraction and territory defense; yet, many songbirds sing at high rates as juveniles and outside these primary contexts as adults. Singing outside primary contexts is critical for song learning and maintenance, and ultimately necessary for breeding success. However, this type of singing (i.e., song "practice") occurs even in the absence of immediate or obvious extrinsic reinforcement; that is, it does not attract mates or repel competitors. Here we review studies that support the hypothesis that song practice is stimulated and maintained by intrinsic reward mechanisms (i...
October 11, 2017: Behavioural Processes
https://www.readbyqxmd.com/read/29030965/fear-affects-parental-care-which-predicts-juvenile-survival-and-exacerbates-the-total-cost-of-fear-on-demography
#19
Blair P Dudeck, Michael Clinchy, Marek C Allen, Liana Y Zanette
Fear itself (perceived predation risk) can affect wildlife demography, but the cumulative impact of fear on population dynamics is not well understood. Parental care is arguably what most distinguishes birds and mammals from other taxa, yet only one experiment on wildlife has tested fear effects on parental food provisioning and the repercussions this has for the survival of dependent offspring, and only during early-stage care. We tested the effect of fear on late-stage parental care of mobile dependent offspring, by locating radio-tagged song sparrow fledglings and broadcasting predator or non-predator playbacks in their vicinity, measuring their parent's behaviour and their own, and tracking the offspring's survival to independence...
October 14, 2017: Ecology
https://www.readbyqxmd.com/read/29030716/prevalence-transmission-and-host-specificity-of-cryptosporidium-spp-in-various-animal-groups-from-two-french-zoos
#20
Marwan Osman, Dima El Safadi, Sadia Benamrouz-Vanneste, Amandine Cian, Romain Moriniere, Nausicaa Gantois, Pilar Delgado-Viscogliosi, Karine Guyot, Stéphanie Bosc, Magali Chabé, Thierry Petit, Eric Viscogliosi, Gabriela Certad
Cryptosporidium represents a major cause of gastrointestinal illness in humans and animals including domestic, wild, and in captivity animals, and more than 30 validated species of Cryptosporidium are recognized as infectious to different hosts such as mammals, birds, reptiles, amphibians, and fish. Therefore, numerous investigations have been conducted worldwide in order to shed light on the epidemiology of this parasite and to explore its potential reservoirs. Few surveys, targeting humans and animals have been carried out regarding the epidemiology of Cryptosporidium spp...
October 13, 2017: Parasitology Research
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