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https://www.readbyqxmd.com/read/27922180/going-domestic-importing-the-study-abroad-experience-the-development-of-a-multicultural-new-york-city-study-away-program
#1
Susan Hayes Lane, Carolyn Huffman, Dana E Brackney, Alyssa Cuddy
PROBLEM: Significant off-campus domestic study away experiences have been shown to be a transformative active learning environment for students and achieve similar learning outcomes as study abroad programs. METHODS: This manuscript describes the conception, development, and pedagogical approach of a faculty-led domestic study away experience in New York City for pre-licensure and post-licensure nursing students as an active learning strategy for developing cultural competence...
December 6, 2016: Nursing Forum
https://www.readbyqxmd.com/read/27921317/effects-of-economics-and-demographics-on-global-fisheries-sustainability
#2
Qi Ding, Yali Wang, Xinjun Chen, Yong Chen
A good understanding of social factors that lead to marine ecological change is important to develop sustainable global fisheries. In this study we analyzed how economic prosperity and population growth in 122 nations might ultimately affect the sustainability of their marine ecosystems during the period of 1970-2010 using a balanced panel model. We used marine Economic Exclusive Zone (EEZ) catch, mean trophic level of fishery landings (MTL), the primary production required to sustain marine catch expressed as percentage of local primary production (%PPR), and the loss in secondary production index (L index) to indicate ecological changes in marine ecosystems...
December 6, 2016: Conservation Biology: the Journal of the Society for Conservation Biology
https://www.readbyqxmd.com/read/27919435/social-return-on-investment-development-and-convergence
#3
Jeremy Nicholls
Social return on investment (SROI) is a relatively new approach to assessing the value created by human activity. This paper explores the development of SROI since its creation in 1996 and concludes by outlining areas for future development. SROI is compared with mainstream global approaches to generating standardized information that informs resource allocation decisions, financial accounting in general, sustainability accounting in the private sector and cost benefit analysis in the public sector.
November 21, 2016: Evaluation and Program Planning
https://www.readbyqxmd.com/read/27912317/production-of-bacillus-amyloliquefaciens-og-and-its-metabolites-in-renewable-media-valorisation-for-biodiesel-production-and-p-xylene-decontamination
#4
Augusto Etchegaray, François Coutte, Gabrielle Chataigné, Max Béchet, Ramon H Z Dos Santos, Valérie Leclère, Philippe Jacques
Biosurfactants are important in many areas; however, costs impede large-scale production. This work aimed to develop a global sustainable strategy for the production of biosurfactants by a novel strain of Bacillus amyloliquefaciens. Initially, Bacillus sp. strain 0G was renamed B. amyloliquefaciens subsp. plantarum (syn. Bacillus velezensis) after analysis of the gyrA and gyrB DNA sequences. Growth in modified Landy's medium produced 3 main recoverable metabolites: surfactin, fengycin, and acetoin, which promote plant growth...
September 2, 2016: Canadian Journal of Microbiology
https://www.readbyqxmd.com/read/27911770/the-right-incentives-enable-ocean-sustainability-successes-and-provide-hope-for-the-future
#5
Jane Lubchenco, Elizabeth B Cerny-Chipman, Jessica N Reimer, Simon A Levin
Healthy ocean ecosystems are needed to sustain people and livelihoods and to achieve the United Nations Sustainable Development Goals. Using the ocean sustainably requires overcoming many formidable challenges: overfishing, climate change, ocean acidification, and pollution. Despite gloomy forecasts, there is reason for hope. New tools, practices, and partnerships are beginning to transform local fisheries, biodiversity conservation, and marine spatial planning. The challenge is to bring them to a global scale...
December 2, 2016: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/27909256/optimizing-the-multisectoral-nutrition-policy-cycle-a-systems-perspective
#6
Sascha Lamstein, Amanda Pomeroy-Stevens, Patrick Webb, Eileen Kennedy
Based on the data collected in Uganda, Nepal, and Ethiopia, the papers included in this supplement fill a critical gap in evidence regarding multisectoral National Nutrition Action Plans. The studies offer new data and new thinking on how and why governance, effective financial decentralization, and improved accountability all matter for nutrition actions in low-income countries. This introductory paper offers an overview of the current state of evidence and thinking on the multisectoral nutrition policy cycle, including how governance and financing support that process...
December 2016: Food and Nutrition Bulletin
https://www.readbyqxmd.com/read/27906123/one-health-research-and-training-and-government-support-for-one-health-in-south-asia
#7
REVIEW
Joanna S McKenzie, Rojan Dahal, Manish Kakkar, Nitish Debnath, Mahmudur Rahman, Sithar Dorjee, Khalid Naeem, Tikiri Wijayathilaka, Barun Kumar Sharma, Nasir Maidanwal, Asmatullah Halimi, Eunmi Kim, Pranab Chatterjee, Brecht Devleesschauwer
INTRODUCTION: Considerable advocacy, funding, training, and technical support have been provided to South Asian countries to strengthen One Health (OH) collaborative approaches for controlling diseases with global human pandemic potential since the early 2000s. It is essential that the OH approach continues to be strengthened given South Asia is a hot spot for emerging and endemic zoonotic diseases. The objectives of this article are to describe OH research and training and capacity building activities and the important developments in government support for OH in these countries to identify current achievements and gaps...
2016: Infection Ecology & Epidemiology
https://www.readbyqxmd.com/read/27905966/rapid-assessment-of-disability-in-the-philippines-understanding-prevalence-well-being-and-access-to-the-community-for-people-with-disabilities-to-inform-the-w-dare-project
#8
Manjula Marella, Alexandra Devine, Graeme Ferdinand Armecin, Jerome Zayas, Ma Jesusa Marco, Cathy Vaughan
BACKGROUND: International recognition that people with disabilities were excluded from the Millennium Development Goals has led to better inclusion of people with disabilities in the recently agreed Global Goals for Sustainable Development (SDGs) 2015-2030. Given the current global agenda for disability inclusion, it is crucial to increase the understanding of the situation of people with disabilities in the Philippines. The aim of this study was to estimate the prevalence of disability and compare the well-being and access to the community between people with and without disabilities...
August 2, 2016: Population Health Metrics
https://www.readbyqxmd.com/read/27905936/multiple-bias-analysis-as-a-technique-to-address-systematic-error-in-measures-of-abortion-related-mortality
#9
Caitlin Gerdts, Jennifer Ahern
BACKGROUND: The UN Millennium Development Goals (MDGs) and Sustainable Development Goals (SDGs) have brought heightened global attention to the measurement of maternal mortality. It is imperative that new and novel approaches be used to measure maternal mortality and to better understand existing data. In this paper we present one approach: an epidemiologic framework for identifying the identification and quantification of systematic error (multiple-bias analysis), outline the necessary steps for investigators interested in conducting multiple-bias analyses in their own data, and suggest approaches for reporting such analyses in the literature...
March 22, 2016: Population Health Metrics
https://www.readbyqxmd.com/read/27905260/ccrm-cultivating-a-culture-of-cooperation-to-advance-the-global-regenerative-medicine-industry
#10
Alanna Evans, Stacey Johnson
Launched in June 2011, CCRM is a unique, Canadian, not-for-profit group that is solely focused on developing and commercializing regenerative medicine, cell and gene therapy technologies. Its mission is to generate sustainable health and economic benefits through global collaborations, and its vision is to be the preferred destination for the best people and companies, technologies, clinical trials and investments in cell and gene therapies, and regenerative medicine.
December 2016: Regenerative Medicine
https://www.readbyqxmd.com/read/27902533/using-simulation-in-global-health-considerations-for-design-and-implementation
#11
Michael B Pitt, Walter J Eppich, Margaret L Shane, Sabrina M Butteris
Providers and educators increasingly participate in global health work during their careers. Simulation can play an important role in both preparing learners for work in resource-limited settings and training providers in these countries. However, little guidance exists for educators interested in creating and implementing scenarios for these settings. We discuss several key considerations unique to global health simulation ranging from addressing common cultural differences surrounding healthcare and varied regional approaches to disease identification and management to understanding precisely what resources exist in the setting and what strategies can be used to provide care when the expected resources are not available...
November 29, 2016: Simulation in Healthcare: Journal of the Society for Simulation in Healthcare
https://www.readbyqxmd.com/read/27900588/modeling-informatics-at-vertex-pharmaceuticals-incorporated-our-philosophy-for-sustained-impact
#12
Georgia McGaughey, W Patrick Walters
Molecular modelers and informaticians have the unique opportunity to integrate cross-functional data using a myriad of tools, methods and visuals to generate information. Using their drug discovery expertise, information is transformed to knowledge that impacts drug discovery. These insights are often times formulated locally and then applied more broadly, which influence the discovery of new medicines. This is particularly true in an organization where the members are exposed to projects throughout an organization, such as in the case of the global Modeling & Informatics group at Vertex Pharmaceuticals...
November 29, 2016: Journal of Computer-aided Molecular Design
https://www.readbyqxmd.com/read/27899117/assistive-products-and-the-sustainable-development-goals-sdgs
#13
Emma Tebbutt, Rebecca Brodmann, Johan Borg, Malcolm MacLachlan, Chapal Khasnabis, Robert Horvath
The Sustainable Development Goals (SDGs) have placed great emphasis on the need for much greater social inclusion, and on making deliberate efforts to reach marginalized groups. People with disabilities are often marginalized through their lack of access to a range of services and opportunities. Assistive products can help people overcome impairments and barriers enabling them to be active, participating and productive members of society. Assistive products are vital for people with disabilities, frailty and chronic illnesses; and for those with mental health problems, and gradual cognitive and physical decline characteristic of aging populations...
November 29, 2016: Globalization and Health
https://www.readbyqxmd.com/read/27898022/enhanced-and-extended-anti-hypertensive-effect-of-vp5-nanoparticles
#14
Ting Yu, Shengnan Zhao, Ziqiang Li, Yi Wang, Bei Xu, Dailong Fang, Fazhan Wang, Zhi Zhang, Lili He, Xiangrong Song, Jian Yang
Hypertension has become a significant global public health concern and is also one of the most common risk factors of cardiovascular disease. Recent studies have shown the promising result of peptides inhibiting angiotensin converting enzyme (ACE) in lowering the blood pressure in both animal models and humans. However, the oral bioavailability and continuous antihypertensive effectiveness require further optimization. Novel nanoparticle-based drug delivery systems are helpful to overcome these barriers. Therefore, a poly-(lactic-co-glycolic) acid nanoparticle (PLGANPs) oral delivery system, of the antihypertensive small peptides Val-Leu-Pro-Val-Pro (VLPVP, VP5) model, was developed in this study and its antihypertensive effect was investigated in spontaneously hypertensive rats (SHRs) for the first time...
November 25, 2016: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/27896932/mesoionic-insecticides-a-novel-class-of-insecticides-that-modulate-nicotinic-acetylcholine-receptors
#15
Caleb W Holyoke, Daniel Cordova, Wenming Zhang, James D Barry, Robert M Leighty, Robert F Dietrich, James J Rauh, Thomas F Pahutski, George P Lahm, My-Hanh Thi Tong, Eric A Benner, John L Andreassi, Rejane M Smith, Daniel R Vincent, Laurie A Christianson, Luis A Teixeira, Vineet Singh, Kenneth A Hughes
BACKGROUND: As the world population grows toward 9 billion by 2050 it is projected that food production will need to increase by 60%. A critical part of this growth includes the safe and effective use of insecticides to reduce the estimated 20-49% loss of global crop yields due to pests. Development of new insecticides will help sustain this protection and overcome insecticide resistance. RESULTS: A novel class of mesoionic compounds has been discovered with exceptional insecticidal activity on a range of Hemiptera and Lepidoptera...
November 29, 2016: Pest Management Science
https://www.readbyqxmd.com/read/27896359/management-of-chronic-hepatitis-c-in-2017
#16
Leona von Köckritz, Jean-François Dufour
Hepatitis C virus (HCV) represents one of the most common aetiologies of chronic liver disease and causes a major global health burden. Globally an estimated 80 million people are chronically infected, but the majority of whom is still undiagnosed. Prior to the discovery of the virus in 1989 a significant number of patients were exposed and consecutively infected with HCV via contaminated transfusions, as it is a blood-borne disease. Chronic HCV infection pursues a progressive course that ultimately results in the development of cirrhosis, liver failure and hepatocellular carcinoma (HCC), if left untreated...
November 29, 2016: Hämostaseologie
https://www.readbyqxmd.com/read/27894008/common-or-multiple-futures-for-end-of-life-care-around-the-world-ideas-from-the-waiting-room-of-history
#17
REVIEW
Shahaduz Zaman, Hamilton Inbadas, Alexander Whitelaw, David Clark
Around the world there is growing interest in the manner in which care is delivered to people at the end of life. However, there is little unanimity on what constitutes a 'good death' and the appropriate societal responses to the issue of delivering culturally relevant and sustainable forms of end of life care in different settings are not subjects of broad agreement. In this critical conceptual paper we focus on the emerging narratives of global palliative care and offer an assessment of their implications...
November 9, 2016: Social Science & Medicine
https://www.readbyqxmd.com/read/27891773/cigarette-smoke-alters-the-secretome-of-lung-epithelial-cells
#18
Alessandra Mossina, Christina Lukas, Juliane Merl-Pham, Franziska E Uhl, Kathrin Mutze, Andrea Schamberger, Claudia Staab-Weijnitz, Jie Jia, Ali Ö Yildirim, Melanie Königshoff, Stefanie M Hauck, Oliver Eickelberg, Silke Meiners
Cigarette smoke is the most relevant risk factor for the development of lung cancer and chronic obstructive pulmonary disease (COPD). Many of its more than 4500 chemicals are highly reactive thereby altering protein structure and function. Here, we used subcellular fractionation coupled to label-free quantitative mass spectrometry to globally assess alterations in the proteome of different compartments of lung epithelial cells upon exposure to cigarette smoke extract. Proteomic profiling of the human alveolar-derived cell line A549 revealed the most pronounced changes within the cellular secretome with preferential downregulation of proteins involved in wound healing and extracellular matrix (ECM) organization...
November 28, 2016: Proteomics
https://www.readbyqxmd.com/read/27887666/contributions-of-national-and-global-health-estimates-to-monitoring-health-related-sustainable-development-goals
#19
Kanitta Bundhamcharoen, Supon Limwattananon, Khanitta Kusreesakul, Viroj Tangcharoensathien
The millennium development goals triggered an increased demand for data on child and maternal mortalities for monitoring progress. With the advent of the sustainable development goals and growing evidence of an epidemiological transition toward non-communicable diseases, policymakers need data on mortality and disease trends and distribution to inform effective policies and support monitoring progress. Where there are limited capacities to produce national health estimates (NHEs), global health estimates (GHEs) can fill gaps for global monitoring and comparisons...
2016: Global Health Action
https://www.readbyqxmd.com/read/27886392/deregulated-expression-of-ezh2-in-congenital-brainstem-disconnection
#20
P G Barth, E Aronica, S Fox, K Fluiter, M A J Weterman, A Poretti, D C Miller, E Boltshauser, B Harding, M Santi, F Baas
Congenital brainstem disconnection (CBSD) is an enigmatic embryo-fetal defect presenting as (sub)total absence of a segment between mesencephalon and lower brainstem. Rostro-caudal limits of the defect vary while the basal pons is always involved and the cerebellum is globally hypoplastic. A recent update and review[1] lists 14 cases, including 3 brain autopsy studies[1-3]. Necrosis and glial- or inflammatory reactions were absent. Inferior olivary nuclei were small or absent, pontine nuclei depleted, and the cerebellar dentate nuclei dysplastic...
November 25, 2016: Neuropathology and Applied Neurobiology
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