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https://www.readbyqxmd.com/read/29678806/a-novel-algorithm-for-determining-the-contextual-characteristics-of-movement-behaviors-by-combining-accelerometer-features-and-wireless-beacons-development-and-implementation
#1
Daniele Magistro, Salvatore Sessa, Andrew P Kingsnorth, Adam Loveday, Alessandro Simeone, Massimiliano Zecca, Dale W Esliger
BACKGROUND: Unfortunately, global efforts to promote "how much" physical activity people should be undertaking have been largely unsuccessful. Given the difficulty of achieving a sustained lifestyle behavior change, many scientists are reexamining their approaches. One such approach is to focus on understanding the context of the lifestyle behavior (ie, where, when, and with whom) with a view to identifying promising intervention targets. OBJECTIVE: The aim of this study was to develop and implement an innovative algorithm to determine "where" physical activity occurs using proximity sensors coupled with a widely used physical activity monitor...
April 20, 2018: JMIR MHealth and UHealth
https://www.readbyqxmd.com/read/29678388/leveraging-algal-omics-to-reveal-potential-targets-for-augmenting-tag-accumulation
#2
REVIEW
Neha Arora, Philip T Pienkos, Vikas Pruthi, Krishna Mohan Poluri, Michael T Guarnieri
Ongoing global efforts to commercialize microalgal biofuels have expedited the use of multi-omics techniques to gain insights into lipid biosynthetic pathways. Functional genomics analyses have recently been employed to complement existing sequence-level omics studies, shedding light on the dynamics of lipid synthesis and its interplay with other cellular metabolic pathways, thus revealing possible targets for metabolic engineering. Here, we review the current status of algal omics studies to reveal potential targets to augment TAG accumulation in various microalgae...
April 17, 2018: Biotechnology Advances
https://www.readbyqxmd.com/read/29678341/trends-in-future-health-financing-and-coverage-future-health-spending-and-universal-health-coverage-in-188-countries-2016-40
#3
(no author information available yet)
BACKGROUND: Achieving universal health coverage (UHC) requires health financing systems that provide prepaid pooled resources for key health services without placing undue financial stress on households. Understanding current and future trajectories of health financing is vital for progress towards UHC. We used historical health financing data for 188 countries from 1995 to 2015 to estimate future scenarios of health spending and pooled health spending through to 2040. METHODS: We extracted historical data on gross domestic product (GDP) and health spending for 188 countries from 1995 to 2015, and projected annual GDP, development assistance for health, and government, out-of-pocket, and prepaid private health spending from 2015 through to 2040 as a reference scenario...
April 17, 2018: Lancet
https://www.readbyqxmd.com/read/29678336/stress-myocardial-blood-flow-heterogeneity-is-a-positron-emission-tomography-biomarker-of-ventricular-arrhythmias-in-patients-with-hypertrophic-cardiomyopathy
#4
Dai-Yin Lu, Hulya Yalçin, Fatih Yalçin, Min Zhao, Sanjay Sivalokanathan, Ines Valenta, Abdel Tahari, Martin G Pomper, Theodore P Abraham, Thomas H Schindler, M Roselle Abraham
Patients with hypertrophic cardiomyopathy (HC) are at increased risk of sudden cardiac death. Abnormalities in myocardial blood flow (MBF) detected by positron emission tomography (PET) are common in HC, but a PET marker that identifies patients at risk of sudden cardiac death is lacking. We hypothesized that disparities in regional myocardial perfusion detected by PET would identify patients with HC at risk of ventricular arrhythmias. To test this hypothesis, we quantified global and regional MBFs by 13 NH3 -PET at rest and at stress, and developed a heterogeneity index to assess MBF heterogeneity in 133 symptomatic patients with HC...
February 6, 2018: American Journal of Cardiology
https://www.readbyqxmd.com/read/29677674/spatial-temporal-change-of-land-surface-temperature-across-285-cities-in-china-an-urban-rural-contrast-perspective
#5
Jian Peng, Jing Ma, Qianyuan Liu, Yanxu Liu, Yi'na Hu, Yingru Li, Yuemin Yue
As an important theme in global climate change and urban sustainable development, the changes of land surface temperature (LST) and surface urban heat island (SUHI) have been more and more focused by urban ecologists. This study used land-use data to identify the urban-rural areas in 285 cities in China and comparatively analyzed LST in urban-rural areas with the perspective of spatial-temporal dynamics heterogeneity. The results showed that, 98.9% of the cities exhibited SUHI effect in summer nighttime and the effect was stronger in northern cities than that in southern cities...
April 17, 2018: Science of the Total Environment
https://www.readbyqxmd.com/read/29676634/impact-of-seasonal-winter-air-pollution-on-health-across-the-lifespan-in-mongolia-and-some-putative-solutions
#6
David Warburton, Nicole Warburton, Clarence Wigfall, Ochir Chimedsuren, Delgerzul Lodoisamba, Sereeter Lodoysamba, Badarch Jargalsaikhan
Environmental pollution of the air, water, and soil comprise an increasingly urgent challenge to global health, well-being, and productivity. The impact of environmental pollution arguably has its greatest impact across the lifespan on children, women of childbearing age, and pregnant women and their unborn children, not only because of their vulnerability during development, but also because of their subsequent longevity. Ulaanbaatar, Mongolia, is a highly instructive, perhaps extreme, example of what happens with recent, rapid urbanization...
April 2018: Annals of the American Thoracic Society
https://www.readbyqxmd.com/read/29668802/achieving-the-sustainable-development-goal-06-in-brazil-the-universal-access-to-sanitation-as-a-possible-mission
#7
Cintia M M Dias, Luiz P Rosa, Jose M A Gomez, Alexandre D'Avignon
Sanitation (which includes national public policies for drinking water, sewage services and waste management) is precarious in Brazil and therefore poses a challenge to a range of actors. Poor sanitation impacts public health, education, the environment, and daily life. Globally, it emits increasing greenhouse gases. Universalization of any major public service appears difficult, if not impossible; however, Brazil's program to universalize access to electricity proves the opposite, as will be shown in this paper...
April 16, 2018: Anais da Academia Brasileira de Ciências
https://www.readbyqxmd.com/read/29660183/interaction-of-maternal-environment-and-allelic-differences-in-seed-vigour-genes-determines-seed-performance-in-brassica-oleracea
#8
Sajjad Awan, Steven Footitt, William E Finch-Savage
Seed vigour is a key trait essential for the production of sustainable and profitable crops. The genetic basis of variation in seed vigour has recently been determined in Brassica oleracea, but the relative importance of the interaction with parental environment is unknown. We produced seeds under a range of maternal environments, including global warming scenarios. Lines were compared that had the same genetic background, but different alleles (high and low vigour) at QTLs responsible for determining seed vigour by altering ABA content and sensitivity...
April 16, 2018: Plant Journal: for Cell and Molecular Biology
https://www.readbyqxmd.com/read/29659460/clozapine-titration-for-people-in-early-psychosis-a-chart-review-and-treatment-guideline
#9
Jacob S Ballon, Hera Ashfaq, Douglas L Noordsy
PURPOSE/BACKGROUND: The use of clozapine, particularly in young people, is often limited by early treatment-emergent adverse effects including drowsiness and lethargy. Concerns about adverse effects, medication adherence, and the need for blood monitoring often impede the use of clozapine in this population, leading to repeated trials of less effective medications. Current clozapine dosing recommendations are based on people further in the course of their illness and thus reflect different responsiveness and sensitivities to antipsychotic medication...
June 2018: Journal of Clinical Psychopharmacology
https://www.readbyqxmd.com/read/29658621/scaling-up-prevention-and-control-of-noncommunicable-diseases-in-the-who-eastern-mediterranean-region
#10
REVIEW
Heba Fouad, Nisreen Abdel Latif, Rachel A Ingram, Asmus Hammerich
Surveillance is an essential component in the campaign to prevent and control noncommunicable diseases (NCDs), both globally and in the Eastern Mediterranean Region (EMR). In order to address the increasing burden from these diseases, countries must first evaluate their own systems and see what steps need to be taken to improve preparedness. Therefore, the WHO Regional Office for the Eastern Mediterranean in Cairo, Egypt, conducts country capacity surveys on a regular basis to compare each Member State's NCD provision to the Framework for Action to implement the UN Political Declaration (2011)...
April 5, 2018: Eastern Mediterranean Health Journal, la Revue de Santé de la Méditerranée Orientale
https://www.readbyqxmd.com/read/29657014/resistance-delaying-strategies-on-uk-sheep-farms-a-cost-benefit-analysis
#11
Jane Learmount, Mike J Glover, Mike A Taylor
UK guidelines for the sustainable control of parasites in sheep (SCOPS) were formulated with the primary aim of delaying development of anthelmintic resistance (AR) on UK sheep farms. Promoting their use requires the engagement and commitment of stakeholders. An important driver for behavioural change in sheep farmers is evidence of economic benefits. A recent evaluation of SCOPS guidance in practice demonstrated a significant reduction in anthelmintic use, suggesting economic benefits through a direct reduction in product and labour costs...
April 30, 2018: Veterinary Parasitology
https://www.readbyqxmd.com/read/29656716/assessing-food-security-using-household-consumption-expenditure-surveys-hces-a-scoping-literature-review
#12
Joanna Russell, Anne Lechner, Quentin Hanich, Aurélie Delisle, Brooke Campbell, Karen Charlton
OBJECTIVE: To meet some of the UN's seventeen Sustainable Development Goals by 2030, there is a need for more effective policy to reduce food insecurity in low-income and lower-middle-income countries (LMIC). Measuring progress towards these goals requires reliable indicators of food security in these countries. Routinely conducted household consumption and expenditure surveys (HCES) provide potentially valuable and nationally representative data sets for this purpose. The present study aimed to assess methods used to determine national food security status using proxy measures from HCES data in LMIC globally...
April 16, 2018: Public Health Nutrition
https://www.readbyqxmd.com/read/29656423/interdisciplinary-knowledge-exchange-across-scales-in-a-globally-changing-marine-environment
#13
Karlie S McDonald, Alistair J Hobday, Elizabeth A Fulton, Peter A Thompson
The effects of anthropogenic global environmental change on biotic and abiotic processes have been reported in aquatic systems across the world. Complex synergies between concurrent environmental stressors and the resilience of the system to regime shifts, which vary in space and time, determine the capacity for marine systems to maintain structure and function with global environmental change. Consequently, an interdisciplinary approach that facilitates the development of new methods for the exchange of knowledge between scientists across multiple scales is required to effectively understand, quantify and predict climate impacts on marine ecosystem services...
April 14, 2018: Global Change Biology
https://www.readbyqxmd.com/read/29653338/long-term-effects-of-adjunctive-perampanel-on-cognition-in-adolescents-with-partial-seizures
#14
Jesus E Piña-Garza, Lieven Lagae, Vicente Villanueva, J Ben Renfroe, Antonio Laurenza, Betsy Williams, Dinesh Kumar, Kimford J Meador
OBJECTIVE: The aim of this study was to evaluate long-term effects of adjunctive perampanel on cognition, efficacy, growth, safety, and tolerability in adolescents with inadequately controlled partial seizures. METHODS: Study 235, a multicenter, randomized, double-blind, placebo-controlled, parallel-group, Phase II study with an open-label extension phase (NCT01161524), was primarily designed to assess the effects of adjunctive perampanel on cognition. Patients (aged ≥12 to <18years) had a diagnosis of epilepsy with inadequately controlled partial seizures, with or without secondary generalization, despite receiving 1-3 antiepileptic drugs...
April 10, 2018: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/29652896/a-cohort-study-of-the-effects-of-older-adult-care-dependence-upon-household-economic-functioning-in-peru-mexico-and-china
#15
Maëlenn M Guerchet, Mariella Guerra, Yueqin Huang, Peter Lloyd-Sherlock, Ana Luisa Sosa, Richard Uwakwe, Isaac Acosta, Peter Ezeah, Sara Gallardo, Zhaorui Liu, Rosie Mayston, Veronica Montes de Oca, Hong Wang, Martin J Prince
BACKGROUND: While links between disability and poverty are well established, there have been few longitudinal studies to clarify direction of causality, particularly among older adults in low and middle income countries. We aimed to study the effect of care dependence among older adult residents on the economic functioning of their households, in catchment area survey sites in Peru, Mexico and China. METHODS: Households were classified from the evolution of the needs for care of older residents, over two previous community surveys, as 'incident care', 'chronic care' or 'no care', and followed up three years later to ascertain economic outcomes (household income, consumption, economic strain, satisfaction with economic circumstances, healthcare expenditure and residents giving up work or education to care)...
2018: PloS One
https://www.readbyqxmd.com/read/29651303/reproducible-high-yielding-biological-caproate-production-from-food-waste-using-a-single-phase-anaerobic-reactor-system
#16
Corine Orline Nzeteu, Anna Christine Trego, Florence Abram, Vincent O'Flaherty
Background: Nowadays, the vast majority of chemicals are either synthesised from fossil fuels or are extracted from agricultural commodities. However, these production approaches are not environmentally and economically sustainable, as they result in the emission of greenhouse gases and they may also compete with food production. Because of the global agreement to reduce greenhouse gas emissions, there is an urgent interest in developing alternative sustainable sources of chemicals. In recent years, organic waste streams have been investigated as attractive and sustainable feedstock alternatives...
2018: Biotechnology for Biofuels
https://www.readbyqxmd.com/read/29650054/global-commitments-and-china-s-endeavors-to-promote-health-and-achieve-sustainable-development-goals
#17
REVIEW
Xiaodong Tan, Qian Wu, Haiyan Shao
BACKGROUND: With its immense population and as the largest developing country in the world, China has made remarkable achievements in health promotion at a relatively low cost. However, China is still faced with challenges such as changes of disease spectrum, the coming era of an aging society, and the risk of environmental pollution. MAIN TEXT: On October 25, 2016, China formally passed the blueprint of "Healthy China 2030," working towards the national goal of reaching a health standard on par with developed countries by 2030, which was also a response to realize the 2030 United Nations Sustainable Development Goals...
April 12, 2018: Journal of Health, Population, and Nutrition
https://www.readbyqxmd.com/read/29649182/applications-of-microalgal-biotechnology-for-disease-control-in-aquaculture
#18
REVIEW
Patai Charoonnart, Saul Purton, Vanvimon Saksmerprome
Aquaculture industries, and in particular the farming of fish and crustaceans, are major contributors to the economy of many countries and an increasingly important component in global food supply. However, the severe impact of aquatic microbial diseases on production performance remains a challenge to these industries. This article considers the potential applications of microalgal technology in the control of such diseases. At the simplest level, microalgae offer health-promoting benefits as a nutritional supplement in feed meal because of their digestibility and high content of proteins, lipids and essential nutrients...
April 12, 2018: Biology
https://www.readbyqxmd.com/read/29648691/implementing-the-end-tb-strategy-in-the-western-pacific-region-translating-vision-into-reality
#19
REVIEW
Kalpeshsinh Rahevar, Paula I Fujiwara, Shalala Ahmadova, Fukushi Morishita, Lee B Reichman
The End TB Strategy aims to end the global tuberculosis (TB) epidemic by 2035 in line with the sustainable development goals targets and has been implemented in the World Health Organization (WHO) Western Pacific Region since 2015. Significant progress has been made in implementing this strategy. However, several challenges still remain. In 2016, an estimated 1.8 million people developed TB in the region, and of these about 20% were missed by national TB programmes. The gap in diagnosis and enrolment as well as treatment completion is greater with drug-resistant TB...
April 12, 2018: Respirology: Official Journal of the Asian Pacific Society of Respirology
https://www.readbyqxmd.com/read/29648592/yeast-2-0-connecting-the-dots-in-the-construction-of-the-world-s-first-functional-synthetic-eukaryotic-genome
#20
I S Pretorius, J D Boeke
Historians of the future may well describe 2018 as the year that the world's first functional synthetic eukaryotic genome became a reality. Without the benefit of hindsight, it might be hard to completely grasp the long-term significance of a breakthrough moment in the history of science like this. The role of synthetic biology in the imminent birth of a budding Saccharomyces cerevisiae yeast cell carrying 16 man-made chromosomes causes the world of science to teeter on the threshold of a future-defining scientific frontier...
June 1, 2018: FEMS Yeast Research
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