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https://www.readbyqxmd.com/read/29029154/interrogating-resilience-in-health-systems-development
#1
Remco van de Pas, Majdi Ashour, Anuj Kapilashrami, Suzanne Fustukian
The Fourth Global Symposium on Health Systems Research was themed around 'Resilient and responsive health systems for a changing world.' This commentary is the outcome of a panel discussion at the symposium in which the resilience discourse and its use in health systems development was critically interrogated. The 2014-15 Ebola outbreak in West-Africa added momentum for the wider adoption of resilient health systems as a crucial element to prepare for and effectively respond to crisis. The growing salience of resilience in development and health systems debates can be attributed in part to development actors and philanthropies such as the Rockefeller Foundation...
September 23, 2017: Health Policy and Planning
https://www.readbyqxmd.com/read/29028964/the-cost-effectiveness-of-hiv-testing-and-treatment-engagement-initiatives-in-british-columbia-canada-2011-2013
#2
B Nosyk, J E Min, E Krebs, X Zang, M Compton, R Gustafson, R Barrios, J S G Montaner
Background: Recognition of the secondary preventive benefits of antiretroviral therapy (ART) has mobilized global efforts to 'seek, test, treat and retain' people living with HIV/AIDS (PLHIV) in HIV care. We aimed to determine the cost-effectiveness of a set of HIV testing and treatment engagement interventions initiated in British Columbia (BC), Canada in 2011-2013. Methods: Using a previously-validated dynamic, compartmental HIV transmission model, linked individual-level health administrative data for PLHIV and aggregate-level HIV testing data, we estimated the cost-effectiveness of primary care testing (hospital, emergency department, outpatient), ART initiation and ART retention initiatives, versus a counterfactual scenario approximating the status quo...
September 26, 2017: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/29028620/carbon-emission-analysis-and-evaluation-of-industrial-departments-in-china-an-improved-environmental-dea-cross-model-based-on-information-entropy
#3
Yongming Han, Chang Long, Zhiqiang Geng, Keyu Zhang
Environmental protection and carbon emission reduction play a crucial role in the sustainable development procedure. However, the environmental efficiency analysis and evaluation based on the traditional data envelopment analysis (DEA) cross model is subjective and inaccurate, because all elements in a column or a row of the cross evaluation matrix (CEM) in the traditional DEA cross model are given the same weight. Therefore, this paper proposes an improved environmental DEA cross model based on the information entropy to analyze and evaluate the carbon emission of industrial departments in China...
October 10, 2017: Journal of Environmental Management
https://www.readbyqxmd.com/read/29027109/scenarios-to-manage-the-hepatitis-c-disease-burden-and-associated-economic-impact-of-treatment-in-turkey
#4
Necati Örmeci, Simten Malhan, İsmail Balık, Gül Ergör, Homie Razavi, Sarah Robbins
BACKGROUND: Hepatitis C virus (HCV) infection is a significant health problem. The aim of this study is to evaluate the cost-effectiveness of HCV treatment and estimate its economic burden in Turkey. METHODS: An Excel-based disease progression model was used to estimate the HCV-infected population for 2015-2030. Direct costs in US dollars (USD) including diagnostic, laboratory, and healthcare costs were provided by experts in the country. Indirect costs were estimated as lost productivity using the World Health Organization (WHO) disability-adjusted life years (DALYs) metric from the Global Burden of Disease study...
October 12, 2017: Hepatology International
https://www.readbyqxmd.com/read/29024032/que-faire-a-bioeconomy-and-solar-energy-institute-at-italy-s-research-council-in-the-context-of-the-global-transition-to-the-solar-economy
#5
Mario Pagliaro, Francesco Meneguzzo
Driven by insight for which new research and education requires new institutional organisation, and drawing on two decades of research and educational efforts, we devise the profile and activities of a new bioeconomy and solar energy institute at Italy's Research Council. We further articulate the institute's activities suggesting avenues on how to deploy sound and giving more useful research, education and policy advice in these crucial fields for making tomorrow's common development sustainable. The outcomes of the study are of general interest, because the transition to a solar economy is of intrinsic global nature and the challenges involved are similar in many countries...
October 12, 2017: Chemistry: a European Journal
https://www.readbyqxmd.com/read/29020981/areas-with-evidence-of-equity-and-their-progress-on-mortality-from-tuberculosis-in-an-endemic-municipality-of-southeast-brazil
#6
Mellina Yamamura, Marcelino Santos Neto, Francisco Chiaravalloti Neto, Luiz Henrique Arroyo, Antônio Carlos Vieira Ramos, Ana Angélica Rêgo de Queiroz, Aylana de Souza Belchior, Danielle Talita Dos Santos, Juliane de Almeida Crispim, Ione Carvalho Pinto, Severina Alice da Costa Uchôa, Regina Célia Fiorati, Ricardo Alexandre Arcêncio
BACKGROUND: In Brazil, people still fall ill and die from tuberculosis (TB), and this can be explained by the significant impasse in the equity of distribution of therapeutic resources to the population as a whole. The aim was to identify geographical areas which have shown progress in terms of equity (of income, schooling and urban occupancy) and test its effect on mortality from TB in a municipality of southeast Brazil. METHODS: It is an ecological study considering TB as the basic cause for deaths registered between 2006 and 2013 on the Mortality Information System and other variables obtained through the Demographic Census of the Brazilian Institute of Geography and Statistics (2010)...
October 12, 2017: Infectious Diseases of Poverty
https://www.readbyqxmd.com/read/29020562/a-question-of-social-justice-how-policies-of-profit-negate-engagement-of-developing-world-bioethicists-and-undermine-global-bioethics
#7
Subrata Chattopadhyay, Catherine Myser, Tiffany Moxham, Raymond De Vries
We identify the ways the policies of leading international bioethics journals limit the participation of researchers working in the resource-constrained settings of low- and middle-income countries (LMICs) in the development of the field of bioethics. Lack of access to essential scholarly resources makes it extremely difficult, if not impossible, for many LMIC bioethicists to learn from, meaningfully engage in, and further contribute to the global bioethics discourse. Underrepresentation of LMIC perspectives in leading journals sustains the hegemony of Western bioethics, limits the presentation of diverse moral visions of life, health, and medicine, and undermines aspirations to create a truly "global" bioethics...
October 2017: American Journal of Bioethics: AJOB
https://www.readbyqxmd.com/read/29017856/planning-an-innovation-marathon-at-an-infectious-disease-conference-with-results-from-the-imed-2016-hackathon
#8
John W Ramatowski, Christopher Xiang Lee, Aikaterini Mantzavino, João Ribas, Winter Guerra, Nicholas D Preston, Eva Schernhammer, Lawrence C Madoff, Britta Lassmann
A hackathon is best described as an "innovation marathon." Derived from the words "hacking" and "marathon," it brings together multi-disciplinary teams to collaborate intensely over a short period of time to define a problem, devise a solution, and design a working prototype. International scientific meetings are conducive to successful hackathons, providing an audience of expert professionals who describe challenges and ensure the proposed solutions address end-user needs. Collaborations with local organizations and academic centers are crucial to attracting complementary specialties such as IT advisors, engineers, and entrepreneurs to develop sustainable projects...
October 7, 2017: International Journal of Infectious Diseases: IJID
https://www.readbyqxmd.com/read/29016383/pathogenesis-of-neisseria-gonorrhoeae-in-the-female-reproductive-tract-neutrophilic-host-response-sustained-infection-and-clinical-sequelae
#9
Jacqueline S Stevens, Alison K Criss
PURPOSE OF REVIEW: Gonorrhea is a major global health concern, caused by the bacterium Neisseria gonorrhoeae. The main clinical feature of acute gonorrhea is neutrophilic influx that is unable to clear infection. Women of reproductive age are predominantly at risk for serious sequelae of gonorrhea, including pelvic inflammatory disease, ectopic pregnancy, and infertility. This review will highlight how neutrophils are recruited to the female reproductive tract (FRT) in response to N. gonorrhoeae, how N...
October 7, 2017: Current Opinion in Hematology
https://www.readbyqxmd.com/read/28994015/exploring-standardized-precipitation-evapotranspiration-index-for-drought-assessment-in-bangladesh
#10
Md Giashuddin Miah, Hasan Muhammad Abdullah, Changyoon Jeong
Drought is a critical issue, and it has a pressing, negative impact on agriculture, ecosystems, livelihoods, food security, and sustainability. The problem has been studied globally, but its regional or even local dimension is sometimes overlooked. Local-level drought assessment is necessary for developing adaptation and mitigation strategies for that particular region. Keeping this in understanding, an attempt was made to create a detailed assessment of drought characteristics at the local scale in Bangladesh...
October 9, 2017: Environmental Monitoring and Assessment
https://www.readbyqxmd.com/read/28992917/the-use-of-large-databases-to-inform-the-development-of-an-intestinal-scoring-system-for-the-poultry-industry
#11
H Kasab-Bachi, A G Arruda, T E Roberts, J B Wilson
There is increasing interest among the poultry industry to develop a comprehensive index that can be used to evaluate overall intestinal health and impact on production performance. The Intestinal Integrity (I(2)) index is a quantitative measurement tool used to assess the intestinal health of flocks that use the Health Tracking System (HTSi), a global surveillance system developed by Elanco Animal Health that captures flock-level information on health and performance. To generate an I(2) index score for a flock, the presence of 23 intestinal health conditions is assessed and recorded, then entered into a mathematical equation...
October 1, 2017: Preventive Veterinary Medicine
https://www.readbyqxmd.com/read/28992878/peginterferon-alfa-2a-for-the-treatment-of-chronic-hepatitis-c-in-the-era-of-direct-acting-antivirals
#12
REVIEW
Yan Huang, Ming-Hui Li, Min Hou, Yao Xie
BACKGROUND: The availability of novel direct-acting antivirals (DAAs) represents a new era of curative hepatitis C virus (HCV) treatment, with over 95% of patients infected with HCV genotype 1 achieving sustained virological response (SVR). Nevertheless, the majority of patients globally are unable to access these treatments because of cost and infrastructure constraints and, thus, remain untreated and uncured. DATA SOURCE: Relevant articles of peginterferon (PegIFN)-based treatments in HCV and sofosbuvir-based treatments, simeprevir, daclatasvir/asunaprevir, ritonavir-boosted paritaprevir/ombitasvir/dasabuvir, and grazoprevir/elbasvir, were searched in PubMed database, including general population and special population...
October 15, 2017: Hepatobiliary & Pancreatic Diseases International: HBPD INT
https://www.readbyqxmd.com/read/28992203/music-therapy-practice-status-and-trends-worldwide-an-international-survey-study
#13
Petra Kern, Daniel B Tague
Background: The field of music therapy is growing worldwide. While there is a wealth of country-specific information available, only a few have databased workforce censuses. Currently, little to no descriptive data exists about the global development of the profession. Objectives: The purpose of this study was to obtain descriptive data about current demographics, practice status, and clinical trends to inform worldwide advocacy efforts, training needs, and the sustainable development of the field...
September 11, 2017: Journal of Music Therapy
https://www.readbyqxmd.com/read/28990537/nanomedicine-for-the-treatment-of-tuberculosis
#14
Zabih Ullah, Md Tanwir Athar, Abdus Samad
BACKGROUND: The diseases tuberculosis, triggered by intracellular pathogens, is a major problem for the global medical professionals. Treatments for these diseases through conventional dosage form consist of long-term therapy with multiple drugs leads to several side effects and contribute to low patient compliance and drug resistance. METHODS: The pathogens are fond to be situated in the intracellular compartments of the cells, which ultimately results in additional blockades to effective treatment...
October 6, 2017: Recent Patents on Anti-infective Drug Discovery
https://www.readbyqxmd.com/read/28990371/exploring-animal-rabies-endemicity-to-inform-control-programmes-in-punjab-india
#15
V J Brookes, G S Gill, C K Singh, B S Sandhu, N K Dhand, B B Singh, J P S Gill, M P Ward
Previous studies estimate that one-third of the annual global burden of rabies (~20,000 cases) occurs in India. Elimination of canine rabies is essential to reduce this burden. Surveillance of animal cases can assess both the risk to humans and the efficacy of control strategies. The objective of this study was to describe the spatial and temporal occurrence of reported confirmed cases of rabies in animals in Punjab, India, from 2004 to 2014. We analysed passive surveillance data on 556 samples submitted from 2004 to 2014 to GADVASU, Ludhiana, Punjab, India...
October 8, 2017: Zoonoses and Public Health
https://www.readbyqxmd.com/read/28988570/alcoholic-liver-disease-pathogenesis-and-current-management
#16
Natalia A Osna, Terrence M Donohue, Kusum K Kharbanda
Excessive alcohol consumption is a global healthcare problem. The liver sustains the greatest degree of tissue injury by heavy drinking because it is the primary site of ethanol metabolism. Chronic and excessive alcohol consumption produces a wide spectrum of hepatic lesions, the most characteristic of which are steatosis, hepatitis, and fibrosis/cirrhosis. Steatosis is the earliest response to heavy drinking and is characterized by the deposition of fat in hepatocytes. Steatosis can progress to steatohepatitis, which is a more severe, inflammatory type of liver injury...
2017: Alcohol Research: Current Reviews
https://www.readbyqxmd.com/read/28987260/treatment-strategies-for-nonalcoholic-fatty-liver-disease-and-nonalcoholic-steatohepatitis
#17
REVIEW
Pegah Golabi, Haley Bush, Zobair M Younossi
Nonalcoholic fatty liver disease (NAFLD) is recognized as a global health problem and as a common cause of chronic liver disease. Nonalcoholic steatohepatitis (NASH) carries an increased risk for development of advanced liver disease. Lifestyle modifications with diet and exercise have been the initial management recommendation. However, these changes are difficult to achieve and sustain overtime. There are pharmacologic agents being considered for treatment of NASH. Some target insulin resistance and others focus on oxidative stress, inflammation, apoptosis, and fibrosis...
November 2017: Clinics in Liver Disease
https://www.readbyqxmd.com/read/28984060/a-practical-approach-to-the-management-of-nocturia
#18
Matthias Oelke, Stefan De Wachter, Marcus J Drake, Antonella Giannantoni, Mike Kirby, Susan Orme, Jonathan Rees, Philip van Kerrebroeck, Karel Everaert
AIM: To raise awareness on nocturia disease burden and to provide simplified aetiologic evaluation and related treatment pathways. METHODS: A multidisciplinary group of nocturia experts developed practical advice and recommendations based on the best available evidence supplemented by their own experiences. RESULTS: Nocturia is defined as the need to void ≥1 time during the sleeping period of the night. Clinically relevant nocturia (≥2 voids per night) affects 2%-18% of those aged 20-40 years, rising to 28%-62% for those aged 70-80 years...
October 5, 2017: International Journal of Clinical Practice
https://www.readbyqxmd.com/read/28983565/the-burden-of-primary-liver-cancer-and-underlying-etiologies-from-1990-to-2015-at-the-global-regional-and-national-level-results-from-the-global-burden-of-disease-study-2015
#19
Tomi Akinyemiju, Semaw Abera, Muktar Ahmed, Noore Alam, Mulubirhan Assefa Alemayohu, Christine Allen, Rajaa Al-Raddadi, Nelson Alvis-Guzman, Yaw Amoako, Al Artaman, Tadesse Awoke Ayele, Aleksandra Barac, Isabela Bensenor, Adugnaw Berhane, Zulfiqar Bhutta, Jacqueline Castillo-Rivas, Abdulaal Chitheer, Jee-Young Choi, Benjamin Cowie, Lalit Dandona, Rakhi Dandona, Subhojit Dey, Daniel Dicker, Huyen Phuc, Donatus U Ekwueme, Maysaa El Sayed Zaki, Florian Fischer, Thomas Fürst, Jamie Hancock, Simon I Hay, Peter Hotez, Sun Ha Jee, Amir Kasaeian, Yousef Khader, Young-Ho Khang, G Anil Kumar, Michael Kutz, Heidi Larson, Alan Lopez, Raimundas Lunevicius, Reza Malekzadeh, Colm McAlinden, Toni Meier, Walter Mendoza, Ali Mokdad, Maziar Moradi-Lakeh, Gabriele Nagel, Quyen Nguyen, Grant Nguyen, Felix Ogbo, George Patton, David M Pereira, Farshad Pourmalek, Mostafa Qorbani, Amir Radfar, Gholamreza Roshandel, Joshua A Salomon, Juan Sanabria, Benn Sartorius, Maheswar Satpathy, Monika Sawhney, Sadaf Sepanlou, Katya Shackelford, Hirbo Shore, Jiandong Sun, Desalegn Tadese Mengistu, Roman Topór-Madry, Bach Tran, Kingsley Nnanna Ukwaja, Vasiliy Vlassov, Stein Emil Vollset, Theo Vos, Tolassa Wakayo, Elisabete Weiderpass, Andrea Werdecker, Naohiro Yonemoto, Mustafa Younis, Chuanhua Yu, Zoubida Zaidi, Liguo Zhu, Christopher J L Murray, Mohsen Naghavi, Christina Fitzmaurice
Importance: Liver cancer is among the leading causes of cancer deaths globally. The most common causes for liver cancer include hepatitis B virus (HBV) and hepatitis C virus (HCV) infection and alcohol use. Objective: To report results of the Global Burden of Disease (GBD) 2015 study on primary liver cancer incidence, mortality, and disability-adjusted life-years (DALYs) for 195 countries or territories from 1990 to 2015, and present global, regional, and national estimates on the burden of liver cancer attributable to HBV, HCV, alcohol, and an "other" group that encompasses residual causes...
October 5, 2017: JAMA Oncology
https://www.readbyqxmd.com/read/28977126/-public-private-partnerships-ppps-in-the-health-sector-global-processes-and-national-dynamics
#20
Celia Almeida
This essay addresses several dimensions that promote and consolidate the growing participation by private stakeholders in the decision-making process in health, emphasizing international and domestic factors that have facilitated and sustained the persistence of the neoliberal political and ideological perspective over the course of nearly thirty years (since the 1990s). The article emphasizes the role of intergovernmental organizations in this process, highlighting public-private interactions at the global and domestic levels, with a specific focus on so-called public-private partnerships (PPPs)...
October 2, 2017: Cadernos de Saúde Pública
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