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JOURNAL ARTICLE
Ayzsa Tannis, Kathryn Miele, Jeffrey M Carlson, Kevin P O'Callaghan, Kate R Woodworth, Breanne Anderson, Aisha Praag, Kourtney Pulliam, Nicole Coppola, Teri' Willabus, Deborah Mbotha, Dejene Abetew, Salvatore Currenti, Nicole D Longcore, Amanda Akosa, Dana Meaney-Delman, Van T Tong, Suzanne M Gilboa, Emily O Olsen
OBJECTIVE: To describe syphilis treatment status and prenatal care among people with syphilis during pregnancy to identify missed opportunities for preventing congenital syphilis. METHODS: Six jurisdictions that participated in SET-NET (Surveillance for Emerging Threats to Pregnant People and Infants Network) conducted enhanced surveillance among people with syphilis during pregnancy based on case investigations, medical records, and linkage of laboratory data with vital records...
April 17, 2024: Obstetrics and Gynecology
#2
JOURNAL ARTICLE
Iulia Filip
No abstract text is available yet for this article.
April 16, 2024: AIDS
#3
JOURNAL ARTICLE
Elizabeth Micks
Rates of sexually transmitted infections (STIs) are increasing in all age groups. Although STI incidence decreases with age, midlife women have risk factors that may lead to STI acquisition and underdiagnosis. Clinicians may assume that older women are not sexually active. Although many STIs are asymptomatic, when midlife women do experience vaginal symptoms, they may be erroneously attributed to menopause changes. Clinicians should follow evidence-based screening recommendations provided by the US Preventive Services Task Force and consider STIs in the differential diagnosis of vaginal symptoms...
April 16, 2024: Menopause: the Journal of the North American Menopause Society
#4
JOURNAL ARTICLE
Kyle T Ganson, Carolyn O'Connor, Jason M Nagata, Alexander Testa, Dylan B Jackson, Nelson Pang, Faye Mishna
Background Sexting is the sending and receiving of nude or partially nude images or videos. Despite it being a part of contemporary relationships, it can have adverse effects. This is particularly the case when receiving non-consensual sexts. To date, there remains a gap in the literature on whether receiving non-consensual sexts is associated with poor sleep. Therefore, the aim of this study was to determine the association between receiving non-consensual sexts and average sleep duration. Methods Data from Wave 2 (2022) of the Canadian Study of Adolescent Health Behaviours (N =906) were analysed...
April 2024: Sexual Health
#5
JOURNAL ARTICLE
Linde L Stewart, Lenka A Vodstrcil, Jacqueline Coombe, Catriona S Bradshaw, Jane S Hocking
Background Bacterial vaginosis (BV) is the most common cause of vaginal discharge in reproductive age women; however, little is known about it after menopause. We aimed to learn more about BV in Australian postmenopausal women. Methods We conducted an online survey (July-September 2021). Participants were recruited via social media and professional networks and asked about demographic characteristics, sexual history and BV experiences. Outcomes of interest were the proportion who had heard of BV, had BV ever, or had BV after menopause...
April 2024: Sexual Health
#6
JOURNAL ARTICLE
Lisa Marie Wadephul, Kathrin Arndts, Gnatoulma Katawa, Eva Dietlmeier, William Horsnell, Achim Hoerauf, Manuel Ritter
Antibody-based fluorescence analysis of female reproductive tissues in research of sexually transmitted diseases allows for an in-depth understanding of protein localization, interactions, and pathogenesis. However, in many cases, cryosectioning is not compatible with biosafety regulations; at all times, exposure of lab personnel and the public to potentially harmful pathogens from biological infectious material must be avoided; thus, formaldehyde fixation is essential. Due to formaldehyde's cross-linking properties, protein detection with antibodies can be impeded...
April 16, 2024: European Journal of Histochemistry: EJH
#7
JOURNAL ARTICLE
Paula E Jayne, Leigh E Szucs, Catherine A Lesesne, Rose Grace Grose, Michelle M Johns
BACKGROUND: Transgender and gender diverse youth experience multiple disproportionate adverse sexual health outcomes. Sexual health education teaches knowledge, attitudes, and skills for promoting sexual health, including reducing risk for sexually transmitted infection, HIV acquisition, and unintended pregnancy. Provision of sexual health education may be protective, but research remains scarce. METHODS: We conducted a multi-stage thematic analysis of 33 in-depth interviews among transgender and gender diverse youth (ages 15-24) living in the southeastern United States on their sexual health education experiences...
April 16, 2024: Perspectives on Sexual and Reproductive Health
#8
JOURNAL ARTICLE
Ayodeji K Adefemi, Adeyemi A Okunowo, Rose I Anorlu
Background Anogenital warts (AGWs) are a prevalent condition resulting from human papillomavirus (HPV) infection, which is the most frequently encountered sexually transmitted infection (STI) on a global scale. Women who are HIV-positive experience a disproportionately high burden of AGWs compared to other populations. It is imperative to comprehend the epidemiological factors linked to the disease within this particular at-risk population. Objectives The objective of the study was to ascertain the prevalence of AGWs and its demographic and socio-biological epidemiological features among recently diagnosed HIV-positive women (HPW) in Lagos, Nigeria...
March 2024: Curēus
#9
JOURNAL ARTICLE
Lirong Xiao, Chaoyu Wang, Sai Ma, Yifan Wang, Liping Guan, Juyi Wu, Wei Zhang, Yao Liu, Yan Wu
Little is known about the outcome for HIV-associated Hodgkin lymphoma (HIV-HL) as this is less common than HIV-negative lymphoma. Therefore, we performed a multi-center study to analyze the clinical characteristics and outcomes of HIV-HL patients in China. Nineteen cases of HIV-HL were diagnosed and treated at three center and including the sixth people's hospital of Zhengzhou, Peking union medical college hospital, and Chongqing university cancer hospital, between December 2013 and June 2022. Data on the clinical features, laboratory results, response, and prognosis were collected and analyzed...
April 15, 2024: Infectious Agents and Cancer
#10
JOURNAL ARTICLE
Harinisri Gunasekaran, Pavithra Sampath, Kannan Thiruvengadam, Muniyandi Malaisamy, Rathinasabapati Ramasamy, Uma Devi Ranganathan, Ramalingam Bethunaickan
BACKGROUND: Tuberculosis (TB) ranks as the second leading cause of death globally among all infectious diseases. This problem is likely due to the lack of biomarkers to differentiate the heterogeneous spectrum of infection. Therefore, the first step in solving this problem is to identify biomarkers to distinguish the different disease states of an individual and treat them accordingly. Circulating microRNA (miRNA) biomarkers are promising candidates for various diseases. In fact, we are yet to conceptualize how miRNA expression influences and predicts TB disease outcomes...
April 15, 2024: BMC Infectious Diseases
#11
JOURNAL ARTICLE
Yuanqi Cai, Xiaoming Zhang, Kuixing Zhang, Jingbo Liang, Pingping Wang, Jinyu Cong, Xin Xu, Mengyao Li, Kunmeng Liu, Benzheng Wei
BACKGROUND: Monkeypox is an emerging infectious disease with confirmed cases and deaths in several parts of the world. In light of this crisis, this study aims to analyze the global knowledge pattern of monkeypox-related patents and explore current trends and future technical directions in the medical development of monkeypox to inform research and policy. METHODS: A comprehensive study of 1,791 monkeypox-related patents worldwide was conducted using the Derwent patent database by descriptive statistics, social network method and linear regression analysis...
April 15, 2024: BMC Infectious Diseases
#12
JOURNAL ARTICLE
Tefera B Agizew, Joseph Soka, Cynthia D Fast, Stephen Mwimanzi, Gilbert Mwesiga, Nashon Edward, Marygiven Stephen, Reheme Kondo, Robert Burny, Christophe Cox, Negussie Beyene
BACKGROUND: African giant pouched rats, trained by Anti-Persoonsmijnen Ontmijnende Product Ontwikkeling (APOPO), have demonstrated their ability to detect tuberculosis (TB) from sputum. We assessed rat-based case detection and compared the mycobacterium bacillary load (MTB-load) in children versus adults. METHODS: From January-December 2022, samples were collected prospectively from 69 Directly Observed Therapy (DOT) facilities' presumed TB patients. Using an average of five rats, APOPO re-evaluated patients with bacteriologically negative (sputum-smear microscopy or Xpert MTB/RIF) results...
April 15, 2024: BMC Infectious Diseases
#13
JOURNAL ARTICLE
Qianting Zhou, Jiayan Li, Lipei Luo, Shuling Min, Li Wang, Lixiu Peng, Yinglan Hou, Ping He, Song He, Shixing Tang, Hongliang Chen
BACKGROUND: Genital infection with Chlamydia trachomatis (C. trachomatis) is a major public health issue worldwide. It can lead to cervicitis, urethritis, and infertility. This study was conducted to determine the characteristics of genital C. trachomatis infection among women attending to the infertility and gynecology clinics. METHODS: Endocervical swabs were collected from 8,221 women for C. trachomatis nucleotide screening and genotyping, while serum samples were collected for C...
April 15, 2024: BMC Infectious Diseases
#14
Thu Kim Nguyen, Yen Hai Nguyen, Hao Thi Nguyen, Quang Minh Khong, Ngoc Kim Tran
No abstract text is available yet for this article.
April 15, 2024: BMC Infectious Diseases
#15
JOURNAL ARTICLE
Alan Bulbin, Julia Shen, Carol Liotta-Bono, Tahir Ahmad
Severe malaria is not routinely considered when evaluating a febrile patient in the postoperative setting. Common bacterial infections, along with adverse drug reactions, are the usual differential concerns. We present a case of severe malaria emerging unexpectedly eight days after routine craniotomy.
April 15, 2024: BMC Infectious Diseases
#16
JOURNAL ARTICLE
Devyashree Medhi, Ridip Dutta, Anisha Sarma, Vaishali Sarma, Baharul Islam, Ribjul Islam, Lahari Saikia
PURPOSE: Neisseria gonorrhoeae (NG), Chlamydia trachomatis (CT) and Mycoplasma hominis (MH), the three most common treatable bacterial sexually transmitted infections (STIs) worldwide can lead to many complications if remain untreated. Screening of high-risk population with highly sensitive methods will lead to significant improvement in patient outcomes and will prevent downward transmission. The advantages of Polymerase chain reaction (PCR) based assay are not only high sensitivity and specificity, but also detection of multiple organisms in a single reaction which reduce the result turn-around time...
April 13, 2024: Indian Journal of Medical Microbiology
#17
JOURNAL ARTICLE
Saugat Karki, Sarah Shaw, Michael Lieberman, Alejandro Pérez, Jonathan Pincus, Priya Jakhmola, Amrita Tailor, Oyinkansola Bukky Ogunrinde, Danielle Sill, Shane Morgan, Miguel Alvarez, Jonathan Todd, Dawn Smith, Ninad Mishra
BACKGROUND: The syndemic nature of gonococcal infections and HIV provides an opportunity to develop a synergistic intervention tool that could address the need for adequate treatment for gonorrhea, screen for HIV infections, and offer pre-exposure prophylaxis (PrEP) for persons who meet the criteria. By leveraging information available on electronic health records, a clinical decision support (CDS) system tool could fulfill this need and improve adherence to Centers for Disease Control and Prevention (CDC) treatment and screening guidelines for gonorrhea, HIV, and PrEP...
April 15, 2024: JMIR Formative Research
#18
JOURNAL ARTICLE
Qianwen Li, Zhi Yang, Kaili Chen, Ming Zhao, Hai Long, Yueming Deng, Haoran Hu, Chen Jia, Meiyu Wu, Zhidan Zhao, Huan Zhu, Suqing Zhou, Mingming Zhao, Pengpeng Cao, Shengnan Zhou, Yang Song, Guishao Tang, Juan Liu, Jiao Jiang, Wei Liao, Wenhui Zhou, Bingyi Yang, Feng Xiong, Suhan Zhang, Xiaofei Gao, Yiqun Jiang, Wei Zhang, Bo Zhang, Yan-Ling He, Liwei Ran, Chunlei Zhang, Wenting Wu, Quzong Suolang, Hanhuan Luo, Xiaojing Kang, Caoying Wu, Hongzhong Jin, Lei Chen, Qing Guo, Guangji Gui, Shanshan Li, Henan Si, Shuping Guo, Hong-Ye Liu, Xiguang Liu, Guo-Zhang Ma, Danqi Deng, Limei Yuan, Jianyun Lu, Jinrong Zeng, Xian Jiang, Xiaoyan Lyu, Liuqing Chen, Bin Hu, Juan Tao, Yuhao Liu, Gang Wang, Guannan Zhu, Zhirong Yao, Qianyue Xu, Bin Yang, Yu Wang, Yan Ding, Xianxu Yang, Hu Kai, Haijing Wu, Qianjin Lu
BACKGROUND: Lupus erythematosus (LE) is a spectrum of autoimmune diseases. Due to the complexity of cutaneous LE (CLE), clinical skin image-based artificial intelligence is still experiencing difficulties in distinguishing subtypes of LE. OBJECTIVES: We aim to develop a multimodal deep learning system (MMDLS) for human-AI collaboration in diagnosis of LE subtypes. METHODS: This is a multi-centre study based on 25 institutions across China to assist in diagnosis of LE subtypes, other eight similar skin diseases and healthy subjects...
April 15, 2024: Journal of the European Academy of Dermatology and Venereology: JEADV
#19
REVIEW
D Potvin, P D'Angelo, S Bennett, J Jankicevic, R Bissonnette
Current drug development strategies present many challenges that can impede drug approval by regulatory agencies. Alternative study models, such as adaptive trial designs, have recently sparked interest, as they provide a flexible and more efficient approach in conducting clinical trials. Adaptive trial designs offer several potential benefits over traditional randomized controlled trials, which include decrease in costs, reduced clinical development time and limiting exposure of patients to potentially ineffective treatments allowing completion of studies with fewer patients...
April 15, 2024: Journal of the European Academy of Dermatology and Venereology: JEADV
#20
JOURNAL ARTICLE
Salome-Joelle Gass, Valerie Yelverton, Jan Ostermann, Sharon Weissman, Helmut Albrecht
Telehealth was rapidly implemented in HIV care during COVID-19 yet remains understudied. To assess the importance of telehealth features, we conducted a mixed-methods study with HIV care providers and people living with HIV. Qualitative interviews and ranking exercises revealed heterogeneity in preference-relevant features of telehealth in HIV care.
May 1, 2024: Sexually Transmitted Diseases
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