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https://www.readbyqxmd.com/read/28227693/using-bioimpedance-spectroscopy-parameters-as-real-time-feedback-during-tdcs
#1
Isar Nejadgholi, Herschel Caytak, Miodrag Bolic, Isar Nejadgholi, Herschel Caytak, Miodrag Bolic, Isar Nejadgholi, Miodrag Bolic, Herschel Caytak
An exploratory analysis is carried out to investigate the feasibility of using BioImpedance Spectroscopy (BIS) parameters, measured on scalp, as real-time feedback during Transcranial Direct Current Stimulation (tDCS). TDCS is shown to be a potential treatment for neurological disorders. However, this technique is not considered as a reliable clinical treatment, due to the lack of a measurable indicator of treatment efficacy. Although the voltage that is applied on the head is very simple to measure during a tDCS session, changes of voltage are difficult to interpret in terms of variables that affect clinical outcome...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28217432/cost-effectiveness-of-grass-pollen-scit-compared-with-slit-and-symptomatic-treatment
#2
Thomas Reinhold, Bernd Brüggenjürgen
BACKGROUND: Whereas specific immunotherapy (SIT) has already been shown to be cost-effective in the treatment of allergic rhinitis compared with symptomatic treatment, only a small number of investigations have compared sublingual (SLIT) and subcutaneous (SCIT) immunotherapeutic approaches. This analysis discusses the cost-effectiveness of SCIT compared with SLIT and a symptomatic treatment modality. At the same time, particular attention is paid to preparation-specific characteristics...
2017: Allergo Journal International
https://www.readbyqxmd.com/read/28217384/decreasing-hospital-length-of-stay-following-lumbar-fusion-utilizing-multidisciplinary-committee-meetings-involving-surgeons-and-other-caretakers
#3
Lisa B E Shields, Lisa Clark, Steven D Glassman, Christopher B Shields
BACKGROUND: Although hospital length of stay (LOS) following lumbar fusion has decreased for a variety of reasons, different institutions find their LOS over the benchmarks published by the national Agency for Healthcare Research and Quality (AHRQ). Over a 3-year period, this prospective study introduced utilization of multidisciplinary committee meetings between surgeons and other caretakers to decrease LOS following spinal fusion surgery without compromising the quality of care. METHODS: A multidisciplinary committee was established to assess factors and institute recommendations that influence hospital LOS following lumbar fusion compared to the national compared to the national AHRQ benchmark at baseline and at 1 and 2 years after adjusting our standard practice...
2017: Surgical Neurology International
https://www.readbyqxmd.com/read/28215797/in-situ-evaluation-of-water-and-energy-consumptions-at-the-end-use-level-the-influence-of-flow-reducers-and-temperature-in-baths
#4
C Matos, A Briga-Sá, I Bentes, D Faria, S Pereira
Nowadays, water and energy consumption is intensifying every year in most of the countries. This perpetual increase will not be supportable in the long run, making urgently to manage these resources on a sustainable way. Domestic consumptions of water and electric energy usually are related and it's important to study that relation, identifying opportunities for use efficient improvement. In fact, without an understanding of water-energy relations, there are water efficiency measures that may lead to unintentional costs in the energy efficiency field...
February 16, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28212961/mapping-to-estimate-health-state-utility-from-non-preference-based-outcome-measures-an-ispor-good-practices-for-outcomes-research-task-force-report
#5
Allan J Wailoo, Monica Hernandez-Alava, Andrea Manca, Aurelio Mejia, Joshua Ray, Bruce Crawford, Marc Botteman, Jan Busschbach
Economic evaluation conducted in terms of cost per quality-adjusted life-year (QALY) provides information that decision makers find useful in many parts of the world. Ideally, clinical studies designed to assess the effectiveness of health technologies would include outcome measures that are directly linked to health utility to calculate QALYs. Often this does not happen, and even when it does, clinical studies may be insufficient for a cost-utility assessment. Mapping can solve this problem. It uses an additional data set to estimate the relationship between outcomes measured in clinical studies and health utility...
January 2017: Value in Health: the Journal of the International Society for Pharmacoeconomics and Outcomes Research
https://www.readbyqxmd.com/read/28211367/high-quality-four-dimensional-cone-beam-ct-reconstruction-using-motion-compensated-total-variation-regularization
#6
Hua Zhang, Jianhua Ma, Zhaoying Bian, Dong Zeng, Qianjin Feng, Wufan Chen
Four dimensional cone-beam computed tomography (4D-CBCT) has great potential clinical value because its ability to describe tumor and organ motion. But the challenge in 4D-CBCT reconstruction is the limited number of projections at each phase, which resulting in the reconstruction full of noise and streak artifacts with the conventional analytical algorithms. To address this problem, in this paper, we propose a motion compensated total variation regularization approach which tries to maximum explore the temporal coherence of the spatial structures among 4D-CBCT phases...
February 17, 2017: Physics in Medicine and Biology
https://www.readbyqxmd.com/read/28211020/goal-directed-fluid-restriction-during-brain-surgery-a-prospective-randomized-controlled-trial
#7
Jinfeng Luo, Jing Xue, Jin Liu, Bin Liu, Li Liu, Guo Chen
BACKGROUND: The value of goal-directed fluid therapy in neurosurgical patients, where brain swelling is a major concern, is unknown. The aim of our study was to evaluate the effect of an intraoperative goal-directed fluid restriction (GDFR) strategy on the postoperative outcome of high-risk patients undergoing brain surgery. METHODS: High-risk patients undergoing brain surgery were randomly assigned to a usual care group (control group) or a GDFR group. In the GDFR group, (1) fluid maintenance was restricted to 3 ml/kg/h of a crystalloid solution and (2) colloid boluses were allowed only in case of hypotension associated with a low cardiac index and a high stroke volume variation...
December 2017: Annals of Intensive Care
https://www.readbyqxmd.com/read/28210769/preprocedural-risk-assessment-prior-to-ppvi-with-cmr-and-cardiac-ct
#8
Ladonna Malone, Brian Fonseca, Thomas Fagan, Jane Gralla, Neil Wilson, Micheal DiMaria, Uyen Truong, Lorna P Browne
Percutaneous pulmonary valve intervention (PPVI) is a less invasive and less costly approach to pulmonary valve replacement compared with the surgical alternative. Potential complications of PPVI include coronary compression and pulmonary arterial injury/rupture. The purpose of this study was to characterize the morphological risk factors for PPVI complication with cardiac MRI and cardiac CTA. A retrospective review of 88 PPVI procedures was performed. 44 patients had preprocedural cardiac MRIs or CTAs available for review...
February 16, 2017: Pediatric Cardiology
https://www.readbyqxmd.com/read/28210351/cross-continuum-tool-is-associated-with-reduced-utilization-and-cost-for-frequent-high-need-users
#9
Lauran Hardin, Adam Kilian, Leslie Muller, Kevin Callison, Michael Olgren
INTRODUCTION: High-need, high-cost (HNHC) patients can over-use acute care services, a pattern of behavior associated with many poor outcomes that disproportionately contributes to increased U.S. healthcare cost. Our objective was to reduce healthcare cost and improve outcomes by optimizing the system of care. We targeted HNHC patients and identified root causes of frequent healthcare utilization. We developed a cross-continuum intervention process and a succinct tool called a Complex Care Map (CCM)© that addresses fragmentation in the system and links providers to a comprehensive individualized analysis of the patient story and causes for frequent access to health services...
February 2017: Western Journal of Emergency Medicine
https://www.readbyqxmd.com/read/28208876/prescribing-pattern-of-antifungal-medications-at-a-tertiary-care-hospital-in-oman
#10
Khalid A Al Balushi, Mohammed A Alzaabi, Fatma Alghafri
INTRODUCTION: Inappropriate use of antifungal agents is implicated in the global burden of antifungal resistance, adverse outcomes like persistent infections, unnecessary exposure and increased cost. Data collection from time to time is to be done in order to have a check on the resistance/sensitivity pattern of the commonly prescribed antifungal drugs. AIM: To describe the pattern of antifungal drug prescription and administration to patients attending a university hospital in Oman...
December 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28203590/surgeon-directed-cost-variation-in-isolated-rotator-cuff-repair
#11
E Bailey Terhune, Peter C Cannamela, Jared S Johnson, Charles D Saad, John Barnes, Janette Silbernagel, Thomas Faciszewski, Kevin G Shea
BACKGROUND: As value becomes a larger component of heath care decision making, cost data can be evaluated for regional and physician variation. Value is determined by outcome divided by cost, and reducing cost increases value for patients. "Third-party spend" items are individual selections by surgeons used to perform procedures. Cost data for third-party spend items provide surgeons and hospitals with important information regarding care value, potential cost-saving opportunities, and the total cost of ownership of specific clinical decisions...
December 2016: Orthopaedic Journal of Sports Medicine
https://www.readbyqxmd.com/read/28192137/a-strategic-approach-for-direct-recovery-and-stabilization-of-fusarium-sp-ict-sac1-cutinase-from-solid-state-fermented-broth-by-carrier-free-cross-linked-enzyme-aggregates
#12
Sandeep A Chaudhari, Rekha S Singhal
The major hurdles in commercial exploitation of cutinase (having both esterolytic and lipolytic activities) with potent industrial applications are its high production cost, operational instability and reusability. Although commercially available in immobilized form, its immobilization process (synthesis of support/carrier) makes it expensive. Herein we tried to address multiple issues of production cost, stability, and reusability, associated with cutinase. Waste watermelon rinds, an agroindustrial waste was considered as a cheap support for solid state fermentation (SSF) for cutinase production by newly isolated Fusarium sp...
February 10, 2017: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/28186429/financial-impact-of-the-robotic-approach-in-liver-surgery-a-comparative-study-of-clinical-outcomes-and-costs-between-the-robotic-and-open-technique-in-a-single-institution
#13
Despoina Daskalaki, Raquel Gonzalez-Heredia, Marc Brown, Francesco M Bianco, Ivo Tzvetanov, Myriam Davis, Jihun Kim, Enrico Benedetti, Pier C Giulianotti
BACKGROUND: One of the perceived major drawbacks of minimally invasive techniques has always been its cost. This is especially true for the robotic approach and is one of the main reasons that has prevented its wider acceptance among hospitals and surgeons. The aim of our study was to evaluate the clinical outcomes and economic impact of robotic and open liver surgery in a single institution. METHODS: Sixty-eight robotic and 55 open hepatectomies were performed at our institution between January 1, 2009 and December 31, 2013...
February 10, 2017: Journal of Laparoendoscopic & Advanced Surgical Techniques. Part A
https://www.readbyqxmd.com/read/28185700/use-of-spatially-distributed-time-integrated-sediment-sampling-networks-and-distributed-fine-sediment-modelling-to-inform-catchment-management
#14
M T Perks, J Warburton, L J Bracken, S M Reaney, S B Emery, S Hirst
Under the EU Water Framework Directive, suspended sediment is omitted from environmental quality standards and compliance targets. This omission is partly explained by difficulties in assessing the complex dose-response of ecological communities. But equally, it is hindered by a lack of spatially distributed estimates of suspended sediment variability across catchments. In this paper, we demonstrate the inability of traditional, discrete sampling campaigns for assessing exposure to fine sediment. Sampling frequencies based on Environmental Quality Standard protocols, whilst reflecting typical manual sampling constraints, are unable to determine the magnitude of sediment exposure with an acceptable level of precision...
February 6, 2017: Journal of Environmental Management
https://www.readbyqxmd.com/read/28184202/cultural-differences-in-opportunity-cost-consideration
#15
Ning Zhang, Li-Jun Ji, Ye Li
Two studies were conducted to investigate cultural differences in opportunity cost consideration between Chinese and Euro-Canadians. Opportunity cost is defined as the cost of a benefit that must be forgone in order to pursue a better alternative (Becker et al., 1974). In both studies, participants read about hypothetical purchase scenarios, and then decided whether they would buy a certain product. Opportunity cost consideration was measured in two ways: (1) participants' thoughts pertaining to other (nonfocal) products while making decisions; (2) participants' decisions not to buy a focal product (Study 1) or a more expensive product (Study 2)...
2017: Frontiers in Psychology
https://www.readbyqxmd.com/read/28181479/multi-atlas-attenuation-correction-supports-full-quantification-of-static-and-dynamic-brain-pet-data-in-pet-mr
#16
Ines Merida, Anthonin Reilhac, Jerome Redoute, Rolf Heckemann, Nicolas Costes, Alexander Hammers
Introduction In simultaneous PET-MR, attenuation maps are not directly available. Essential for absolute radioactivity quantification, they need to be derived from MR or PET data to correct for gamma photon attenuation by the imaged object. We evaluate a multi-atlas attenuation correction method for brain imaging (MaxProb) on static [18F]FDG PET and, for the first time, on dynamic PET, using the serotoninergic tracer [18F]MPPF. Methods A database of 40 MR/CT image pairs (atlases) was used. The MaxProb method synthesises subject-specific pseudo-CTs by registering each atlas to the target subject space...
February 9, 2017: Physics in Medicine and Biology
https://www.readbyqxmd.com/read/28177712/investigating-human-skeletal-muscle-physiology-with-unilateral-exercise-models-when-one-limb-is-more-powerful-than-two
#17
Martin J MacInnis, Chris McGlory, Martin J Gibala, Stuart M Phillips
Direct sampling of human skeletal muscle using the needle biopsy technique can facilitate insight into the biochemical and histological responses resulting from changes in exercise or feeding. However, the muscle biopsy procedure is invasive, and analyses are often expensive, which places pragmatic restraints on sample sizes. The unilateral exercise model can serve to increase statistical power and reduce the time and cost of a study. With this approach, two limbs of a participant are randomized to one of two treatments that can be applied almost concurrently or sequentially depending on the nature of the intervention...
January 24, 2017: Applied Physiology, Nutrition, and Metabolism, Physiologie Appliquée, Nutrition et Métabolisme
https://www.readbyqxmd.com/read/28176678/a-non-axial-superconducting-magnet-design-for-optimized-patient-access-and-minimal-sad-for-use-in-a-linac-mr-hybrid-proof-of-concept
#18
Shima Yaghoobpour Tari, Keith Wachowicz, B Gino Fallone
A prototype rotating hybrid magnetic resonance (MR) imaging system and linac has been developed to allow for simultaneous imaging and radiation delivery parallel to B0. However, the design of a compact magnet capable of rotation in a small vault with sufficient patient access and a typical clinical source-to-axis distance (SAD) is challenging. This work presents a novel superconducting magnet design as a proof of concept that allows for a reduced SAD and ample patient access by moving the superconducting coils to the side of the yoke...
February 8, 2017: Physics in Medicine and Biology
https://www.readbyqxmd.com/read/28169210/a-comparison-of-concentrations-of-sodium-and-related-nutrients-potassium-total-dietary-fiber-total-and-saturated-fat-and-total-sugar-in-private-label-and-national-brands-of-popular-sodium-contributing-commercially-packaged-foods-in-the-united-states
#19
Jaspreet K C Ahuja, Pamela R Pehrsson, Mary Cogswell
BACKGROUND: Private-label brands account for about one in four foods sold in US supermarkets. They provide value to consumers due to their low cost. We know of no US studies comparing the nutrition content of private-label products with corresponding national brand products. OBJECTIVE: The objective was to compare concentrations of sodium and related nutrients (potassium, total dietary fiber, total and saturated fat, and total sugar) in popular sodium-contributing, commercially packaged foods by brand type (national or private-label brand)...
February 3, 2017: Journal of the Academy of Nutrition and Dietetics
https://www.readbyqxmd.com/read/28163878/foraging-in-an-unsteady-world-bumblebee-flight-performance-in-field-realistic-turbulence
#20
J D Crall, J J Chang, R L Oppenheimer, S A Combes
Natural environments are characterized by variable wind that can pose significant challenges for flying animals and robots. However, our understanding of the flow conditions that animals experience outdoors and how these impact flight performance remains limited. Here, we combine laboratory and field experiments to characterize wind conditions encountered by foraging bumblebees in outdoor environments and test the effects of these conditions on flight. We used radio-frequency tags to track foraging activity of uniquely identified bumblebee (Bombus impatiens) workers, while simultaneously recording local wind flows...
February 6, 2017: Interface Focus
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