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https://www.readbyqxmd.com/read/29772593/-coagulation-monitoring-and-bleeding-management-in-cardiac-surgery
#1
Berthold Bein, Robert Schiewe
The transfusion of allogeneic blood products is associated with increased morbidity and mortality. An impaired hemostasis is frequently found in patients undergoing cardiac surgery and may in turn cause bleeding and transfusions. A goal directed coagulation management addressing the often complex coagulation disorders needs sophisticated diagnostics. This may improve both patients' outcome and costs. Recent data suggest that coagulation management based on a rational algorithm is more effective than traditional therapy based on conventional laboratory variables such as PT and INR...
May 2018: Anästhesiologie, Intensivmedizin, Notfallmedizin, Schmerztherapie: AINS
https://www.readbyqxmd.com/read/29765208/primary-nonadherence-to-chronic-disease-medications-a-meta-analysis
#2
REVIEW
Mark Lemstra, Chijioke Nwankwo, Yelena Bird, John Moraros
Background: Medication nonadherence is a global problem that requires urgent attention. Primary nonadherence occurs when a patient consults with a medical doctor, receives a referral for medical therapy but never fills the first dispensation for the prescription medication. Nonadherence to chronic disease medications costs the USA ~$290 billion (USD) every year in avoidable health care costs. In Canada, it is estimated that 5.4% of all hospitalizations are due to medication nonadherence...
2018: Patient Preference and Adherence
https://www.readbyqxmd.com/read/29761340/reduction-of-direct-health-costs-associated-with-pertussis-vaccination-with-acellular-vaccines-in-children-aged-0-9-years-with-pertussis-in-catalonia-spain
#3
Pedro Plans-Rubió, Encarna Navas, Pere Godoy, Gloria Carmona, Angela Domínguez, Mireia Jané, Carmen Muñoz-Almagro, Pedro Brotons
OBJECTIVES: The aim of this study was to assess direct health costs in children with pertussis aged 0-9 years who were vaccinated, partially vaccinated, and unvaccinated during childhood, and to assess the association between pertussis costs and pertussis vaccination in Catalonia (Spain) in 2012-2013. METHODS: Direct healthcare costs included pertussis treatment, pertussis detection, and preventive chemotherapy of contacts. Pertussis patients were considered vaccinated when they had received 4-5 doses, and unvaccinated or partially vaccinated when they had received 0-3 doses of vaccine...
May 14, 2018: PharmacoEconomics Open
https://www.readbyqxmd.com/read/29758896/evaluation-and-uncertainty-estimation-of-the-impact-of-air-quality-modelling-on-crop-yields-and-premature-deaths-using-a-multi-model-ensemble
#4
Efisio Solazzo, Angelo Riccio, Rita Van Dingenen, Luana Valentini, Stefano Galmarini
This study promotes the critical use of air pollution modelling results for health and agriculture impacts, with the primary goal of providing more reliable estimates to decision makers. To date, the accuracy of air quality (AQ) models and the effects of model-to-model result variability (which we will refer to as model uncertainty) on impact assessment studies have been often ignored, thus undermining the robustness of the information used in the decision making process and the confidence in the results obtained...
August 15, 2018: Science of the Total Environment
https://www.readbyqxmd.com/read/29757360/decision-analysis-supports-the-use-of-drain-amylase-based-enhanced-recovery-method-after-esophagectomy
#5
B Jiang, V P Ho, J Ginsberg, S J Fu, Y Perry, L Argote-Greene, P A Linden, C W Towe
Postesophagectomy anastomotic leak is a common postsurgical complication. The current standard method of detecting leak is esophagram usually late in the postoperative period. Perianastomotic drain amylase level had shown promising results in early detection anastomosis leak. Previous studies have shown that postoperative day 4 amylase level is more specific and sensitive than esophagram. The purpose of this study is to determine if implementing a drain amylase-based screening method for anastomotic leak can reduce length of stay and hospital cost relative to a traditional esophagram-based pathway...
May 10, 2018: Diseases of the Esophagus: Official Journal of the International Society for Diseases of the Esophagus
https://www.readbyqxmd.com/read/29749350/adaptive-optimal-input-design-and-parametric-estimation-of-nonlinear-dynamical-systems-application-to-neuronal-modeling
#6
Mahmoud K Madi, Fadi N Karameh
Many physical models of biological processes including neural systems are characterized by parametric nonlinear dynamical relations between driving inputs, internal states, and measured outputs of the process. Fitting such models using experimental data (data assimilation) is a challenging task since the physical process often operates in a noisy, possibly non-stationary environment; moreover, conducting multiple experiments under controlled and repeatable conditions can be impractical, time consuming or costly...
May 11, 2018: Journal of Neural Engineering
https://www.readbyqxmd.com/read/29742246/analysis-of-direct-costs-of-decompressive-craniectomy-in-victims-of-traumatic-brain-injury
#7
Guilherme Lellis Badke, João Luiz Vitorino Araujo, Flávio Key Miura, Vinicius Monteiro de Paula Guirado, Nelson Saade, Aline Lariessy Campos Paiva, Tiago Marques Avelar, Charles Alfred Grander Pedrozo, José Carlos Esteves Veiga
BACKGROUND: Decompressive craniectomy is a procedure required in some cases of traumatic brain injury (TBI). This manuscript evaluates the direct costs and outcomes of decompressive craniectomy for TBI in a developing country and describes the epidemiological profile. METHODS: A retrospective study was performed using a five-year neurosurgical database, taking a sample of patients with TBI who underwent decompressive craniectomy. Several variables were considered and a formula was developed for calculating the total cost...
April 2018: Arquivos de Neuro-psiquiatria
https://www.readbyqxmd.com/read/29741769/contrasting-seasonal-and-aseasonal-environments-across-stages-of-the-annual-cycle-in-the-rufous-collared-sparrow-zonotrichia-capensis-differences-in-endocrine-function-proteome-and-body-condition
#8
Paulina L González-Gómez, Valentina Echeverria, Cristian F Estades, Jonathan H Perez, Jesse S Krause, Pablo Sabat, Jonathon Li, Dietmar Kültz, John C Wingfield
1.The timing and duration of life history stages (LHS) within the annual cycle can be affected by local environmental cues which are integrated through endocrine signaling mechanisms and changes in protein function. Most animals express a single LHS within a given period of the year because synchronous expression of LHSs is thought to be too costly energetically. However, in very rare and extremely stable conditions, breeding and molt have been observed to overlap extensively in Rufous-collared sparrows (Zonotrichia capensis) living in valleys of the Atacama Desert - one of the most stable and aseasonal environments on Earth...
May 9, 2018: Journal of Animal Ecology
https://www.readbyqxmd.com/read/29738400/using-a-validated-middle-age-and-geriatric-risk-tool-to-identify-early-48hr-hospital-mortality-and-associated-cost-of-care
#9
Ariana Lott, Jack Haglin, Hesham Saleh, Jordan Hall, Kenneth A Egol, Sanjit R Konda
OBJECTIVES: 1) Demonstrate that a validated trauma triage score for middle-aged and geriatric patients could identify those at high risk for mortality within the first two days of hospitalization and 2) determine the cost of care for this cohort of patients DESIGN:: Prospective cohort study SETTING:: Single Level 1 Trauma Center PATIENTS:: Patients 55 years and older who were evaluated in the emergency department setting by Orthopaedics or who met American College of Surgeons Tier 1-3 criteria INTERVENTION:: Calculation of validated trauma triage score, Score for Trauma Triage in Geriatric and Middle Aged (STTGMA), using patient's demographic, injury severity, and functional statusMain Outcome Measurements: length of stay, inpatient mortality, time between presentation and time of death, and direct variable costs of hospitalization RESULTS:: A total of 1470 consecutive patients (mean age of 72...
May 3, 2018: Journal of Orthopaedic Trauma
https://www.readbyqxmd.com/read/29735343/home-ranges-of-lions-in-the-kalahari-botswana-exhibit-vast-sizes-and-high-temporal-variability
#10
André Zehnder, Stephen Henley, Robert Weibel
The central Kalahari region in Botswana is one of the few remaining ecosystems with a stable lion population. Yet, relatively little is known about the ecology of the lions there. As an entry point, home range estimations provide information about the space utilization of the studied animals. The home ranges of eight lions in this region were determined to investigate their spatial overlaps and spatiotemporal variations. We found that, except for MCP, all home range estimators yielded comparable results regarding size and shape...
April 9, 2018: Zoology: Analysis of Complex Systems, ZACS
https://www.readbyqxmd.com/read/29719480/nuclear-medicine-in-prostate-cancer-a-new-era-for-radiotracers
#11
REVIEW
Vincenzo Cuccurullo, Giuseppe Danilo Di Stasio, Luigi Mansi
Natural history of prostate cancer (PCa) is extremely variable, as it ranges from indolent and slow growing tumors to highly aggressive histotypes. Genetic background and environmental factors co-operate to the genesis and clinical manifestation of the tumor and include among the others race, family, specific gene variants (i.e., BRCA1 and BRCA2 mutations), acute and chronic inflammation, infections, diet and drugs. In this scenario, remaining actual the clinical interest of bone scan (BS) in detecting skeletal metastases, an important role in diagnostic imaging may be also carried out by, positron emission tomography/computed tomography (PET/CT) and PET/magnetic resonance imaging (PET/MRI), which combine morphological information provided by CT and MRI with functional and metabolic data provided by PET acquisitions...
April 2018: World Journal of Nuclear Medicine
https://www.readbyqxmd.com/read/29718416/drivers-of-variability-in-90-day-cost-for-elective-anterior-cervical-discectomy-and-fusion-for-cervical-degenerative-disease
#12
Silky Chotai, Ahilan Sivaganesan, Scott L Parker, John A Sielatycki, Matthew J McGirt, Clinton J Devin
BACKGROUND: Value-based episode of care reimbursement models is being investigated to curb unsustainable health care costs. Any variation in the cost of index spine surgery can affect the payment bundling during the 90-d global period. OBJECTIVE: To determine the drivers of variability in cost for patients undergoing elective anterior cervical discectomy and fusion (ACDF) for degenerative cervical spine disease. METHODS: Four hundred forty-five patients undergoing elective ACDF for cervical spine degenerative diagnoses were included in the study...
May 1, 2018: Neurosurgery
https://www.readbyqxmd.com/read/29716580/cost-effectiveness-of-the-mobile-application-tcapp-combined-with-face-to-face-cbt-treatment-compared-to-face-to-face-cbt-treatment-alone-for-patients-with-an-eating-disorder-study-protocol-of-a-multi-centre-randomised-controlled-trial
#13
Dimitra Anastasiadou, Francisco Lupiañez-Villanueva, Clara Faulí, Jordina Arcal Cunillera, Eduardo Serrano-Troncoso
BACKGROUND: The clinical utility of the existing apps for people with eating disorders (EDs) is not clear. The TCApp has been specifically developed for people with EDs, is based on the principles of Cognitive Behavioural Treatment (CBT) and allows a bidirectional link between the patient and the therapist. The objectives of the study are, first, to assess the clinical efficacy of a combined intervention for Eating Disorders (EDs) that includes an online intervention through the TCApp plus standard face-to-face CBT in comparison to standard face-to-face CBT alone, and second, to examine the cost-effectiveness of the TCApp and identify potential predicting, moderating and mediating variables that promote or hinder the implementation of the TCApp in ED units in Spain...
May 2, 2018: BMC Psychiatry
https://www.readbyqxmd.com/read/29714617/pharmacotherapeutic-reports-as-tools-for-detecting-discrepancies-in-continuity-of-care
#14
Elena Yaiza Romero-Ventosa, Mónica Gayoso-Rey, Marisol Samartín-Ucha, Pablo Lamas-Domínguez, Martín Rubianes-González, David Rodríguez-Lorenzo, María Holanda Rodríguez-Vázquez, Julio García-Comesaña, Guadalupe Piñeiro-Corrales
BACKGROUND: The care transition is the time when more medication errors occur. The aim of this study is to analyze the usefulness of a pharmacotherapeutic report model at hospital discharge to prevent medication errors and to simplify pharmacotherapy during a patient's transition from the hospital to primary care. METHODS: Prospective study including patients diagnosed with chronic obstructive pulmonary disease who were admitted to a short-stay unit or an emergency room...
January 2018: Therapeutic Innovation & Regulatory Science
https://www.readbyqxmd.com/read/29712525/analysis-of-cerebrovascular-aneurysm-treatment-cost-retrospective-cohort-comparison-of-clipping-coiling-and-flow-diversion
#15
Spencer Twitchell, Hussam Abou-Al-Shaar, Jared Reese, Michael Karsy, Ilyas M Eli, Jian Guan, Philipp Taussky, William T Couldwell
OBJECTIVE With the continuous rise of health care costs, hospitals and health care providers must find ways to reduce costs while maintaining high-quality care. Comparing surgical and endovascular treatment of intracranial aneurysms may offer direction in reducing health care costs. The Value-Driven Outcomes (VDO) database at the University of Utah identifies cost drivers and tracks changes over time. In this study, the authors evaluate specific cost drivers for surgical clipping and endovascular management (i...
May 2018: Neurosurgical Focus
https://www.readbyqxmd.com/read/29712516/assessment-of-cost-drivers-and-cost-variation-for-lumbar-interbody-fusion-procedures-using-the-value-driven-outcomes-database
#16
Spencer Twitchell, Michael Karsy, Jared Reese, Jian Guan, William T Couldwell, Andrew Dailey, Erica F Bisson
OBJECTIVE Efforts to examine the value of care-combining both costs and quality-are gaining importance in the current health care climate. This thrust is particularly evident in treating common spinal disease where both incidences and costs are generally high and practice patterns are variable. It is often challenging to obtain direct surgical costs for these analyses, which hinders the understanding of cost drivers and cost variation. Using a novel tool, the authors sought to understand the costs of posterior lumbar arthrodesis with interbody devices...
May 2018: Neurosurgical Focus
https://www.readbyqxmd.com/read/29710177/economics-of-palliative-care-for-hospitalized-adults-with-serious-illness-a-meta-analysis
#17
Peter May, Charles Normand, J Brian Cassel, Egidio Del Fabbro, Robert L Fine, Reagan Menz, Corey A Morrison, Joan D Penrod, Chessie Robinson, R Sean Morrison
Importance: Economics of care for adults with serious illness is a policy priority worldwide. Palliative care may lower costs for hospitalized adults, but the evidence has important limitations. Objective: To estimate the association of palliative care consultation (PCC) with direct hospital costs for adults with serious illness. Data Sources: Systematic searches of the Embase, PsycINFO, CENTRAL, PubMed, CINAHL, and EconLit databases were performed for English-language journal articles using keywords in the domains of palliative care (eg, palliative, terminal) and economics (eg, cost, utilization), with limiters for hospital and consultation...
April 30, 2018: JAMA Internal Medicine
https://www.readbyqxmd.com/read/29706083/urban-suburban-differences-in-gp-requests-for-lumbosacral-spine-radiographs-in-a-primary-healthcare-centre-in-malta
#18
Glorianne Pullicino, Philip Sciortino, Sean Francalanza, Paul Sciortino, Richard Pullicino
INTRODUCTION: Due to demographic changes, growing demands, technological developments and rising healthcare costs, analysis of resources in rural and urban primary care clinics is crucial. However, data on primary care provision in rural and suburban areas are lacking. Moreover, health inequities in small island communities tend to be reduced by social homogeneity and an almost indiscernible urban-rural difference. The aim of the study was to examine the urban-suburban differences in the indications for lumbosacral spine radiographs in a public primary healthcare centre in Malta...
April 2018: Rural and Remote Health
https://www.readbyqxmd.com/read/29702033/adding-multimedia-cues-to-medical-providers-online-biographies-do-pictures-video-and-b-roll-matter
#19
Evan K Perrault
Developing engaging online healthcare provider biographies for prospective patients to consult is becoming a big business. Health-care systems are beginning to add more multichannel components-like videos-to these provider search tools at increasingly higher costs. Prior research finds that prospective patients desire videos offering additional footage (i.e., b-roll) displaying how a provider might interact with a patient during a consultation. Shooting and editing b-roll footage to add to providers' videos takes additional time and resources...
April 27, 2018: Journal of Health Communication
https://www.readbyqxmd.com/read/29695970/sport-specific-assessment-of-the-effectiveness-of-neuromuscular-training-in-young-athletes
#20
REVIEW
Erika Zemková, Dušan Hamar
Neuromuscular training in young athletes improves performance and decreases the risk of injuries during sports activities. These effects are primarily ascribed to the enhancement of muscle strength and power but also balance, speed and agility. However, most studies have failed to demonstrate significant improvement in these abilities. This is probably due to the fact that traditional tests do not reflect training methods (e.g., plyometric training vs. isometric or isokinetic strength testing, dynamic balance training vs...
2018: Frontiers in Physiology
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