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Temitope M John, Joke A Badejo, Segun I Popoola, David O Omole, Jonathan A Odukoya, Priscilla O Ajayi, Mary Aboyade, Aderemi A Atayero
This data article presents data of academic performances of undergraduate students in Science, Technology, Engineering and Mathematics (STEM) disciplines in Covenant University, Nigeria. The data shows academic performances of Male and Female students who graduated from 2010 to 2014. The total population of samples in the observation is 3046 undergraduates mined from Biochemistry (BCH), Building technology (BLD), Computer Engineering (CEN), Chemical Engineering (CHE), Industrial Chemistry (CHM), Computer Science (CIS), Civil Engineering (CVE), Electrical and Electronics Engineering (EEE), Information and Communication Engineering (ICE), Mathematics (MAT), Microbiology (MCB), Mechanical Engineering (MCE), Management and Information System (MIS), Petroleum Engineering (PET), Industrial Physics-Electronics and IT Applications (PHYE), Industrial Physics-Applied Geophysics (PHYG) and Industrial Physics-Renewable Energy (PHYR)...
June 2018: Data in Brief
Min Lu, Xiangwei He
Distinct chromatin organization features, such as centromeres and heterochromatin domains, are inherited epigenetically. However, the mechanisms that modulate the accuracy of epigenetic inheritance, especially at the individual nucleosome level, are not well understood. Here, using ChIP and next-generation sequencing (ChIP-Seq), we characterized Ccp1, a homolog of the histone chaperone Vps75 in budding yeast that functions in centromere chromatin duplication and heterochromatin maintenance in fission yeast (Schizosaccharomyces pombe)...
June 13, 2018: Journal of Biological Chemistry
Johan O Westman, Jonas Nyman, Richard M A Manara, Valeria Mapelli, Carl Johan Franzén
Yeast flocculation is the reversible formation of multicellular complexes mediated by lectin-like cell wall proteins binding to neighbouring cells. Strong flocculation can improve the inhibitor tolerance and fermentation performance of yeast cells in second generation bioethanol production. The strength of flocculation increases with the size of the flocculation protein and is strain dependent. However, the large number of internal repeats in the sequence of FLO1 from Saccharomyces cerevisiae S288c makes it difficult to recombinantly express the gene to its full length...
June 2018: Metabolic Engineering Communications
Xi-Yang Cui, Yi-Cen Ge, Siu Min Tan, Huan Jiang, Davin Tan, Yunpeng Lu, Richmond Lee, Choon-Hong Tan
Highly enantioselective allylic alkynylation of racemic bromides under biphasic condition is furnished in this report. This approach employs functionalized terminal alkynes as pro-nucleophiles and provides 6- and 7-membered cyclic 1,4-enynes with high yields and excellent enantioselectivities (up to 96% ee) under mild conditions. Enantio-retentive derivatizations highlight the synthetic utility of this transformation. Cold-spray ionization mass spectrometry (CSI-MS) and X-ray crystallography were used to identify catalytic intermediates, which include guanidinium cuprate ion pairs and a copper-alkynide complex...
June 12, 2018: Journal of the American Chemical Society
Rui Fa, Domenico Cozzetto, Cen Wan, David T Jones
Machine learning methods for protein function prediction are urgently needed, especially now that a substantial fraction of known sequences remains unannotated despite the extensive use of functional assignments based on sequence similarity. One major bottleneck supervised learning faces in protein function prediction is the structured, multi-label nature of the problem, because biological roles are represented by lists of terms from hierarchically organised controlled vocabularies such as the Gene Ontology...
2018: PloS One
Robin Babadjouni, Timothy Wen, Daniel A Donoho, Ian A Buchanan, Steven Y Cen, Rick A Friedman, Arun Amar, Jonathan J Russin, Steven L Giannotta, William J Mack, Frank J Attenello
BACKGROUND: Hospital readmissions are commonly linked to elevated health care costs, with significant financial incentive introduced by the Affordable Care Act to reduce readmissions. OBJECTIVE: To study the association between patient, hospital, and payer factors with national rate of readmission in acoustic neuroma surgery. METHODS: All adult inpatients undergoing surgery for acoustic neuroma in the newly introduced Nationwide Readmissions Database from 2013 to 2014 were included...
June 8, 2018: Neurosurgery
Bino A Varghese, Frank Chen, Darryl H Hwang, Steven Y Cen, Inderbir S Gill, Vinay A Duddalwar
OBJECTIVE: To test the feasibility of 2D fast Fourier transforms (FFT)-based imaging metrics in differentiating solid, non-macroscopic fat containing, enhancing renal masses using contrast-enhanced computed tomography (CECT) images. We quantify image-based intra-tumoral textural variations (indicator of tumor heterogeneity) using frequency-based (FFT) imaging metrics. METHODS: In this Institutional Review Board (IRB) approved, Health Insurance Portability and Accountability Act (HIPAA) compliant, retrospective case-control study, we evaluated 156 patients with predominantly solid, non-macroscopic fat containing, enhancing renal masses identified between June 2009 and June 2016...
June 11, 2018: British Journal of Radiology
Yue Li, Xueya Cai, Charlene Harrington, Michael Hasselberg, Yeates Conwell, Xi Cen, Helena Temkin-Greener
This study aimed to examine racial and ethnic differences in significant depressive symptoms among long-term nursing home residents. We analyzed the 2014 national Minimum Data Set linked to a nursing home file, and estimated multivariable logistic regressions to determine the associations of race and ethnicities with significant depressive symptoms (score≥10 on the 9-item Patient Health Questionnaire [PHQ-9] scale), and whether associations were explained by resident and nursing home covariates. Stratified analyses further determined independent associations in subgroups of residents...
June 8, 2018: Journal of Aging & Social Policy
Meng Wu, Jun-Jie Shi, Min Zhang, Yi-Min Ding, Hui Wang, Yu-Lang Cen, Jing Lu
Recently, two-dimensional (2D) few-layer InSe nanosheets have become one of the most interesting materials due to their excellent electron transport, wide bandgap tunability and good metal contact. However, their low photoluminescence (PL) efficiency and hole mobility seriously restrict their application in 2D InSe-based nano-devices. Here, by exerting a suitable compressive strain, a remarkable modification for the electronic structure and the optical and transport properties of 1- to 5-layer InSe has been confirmed by powerful GW-BSE calculations...
June 8, 2018: Nanoscale
James Oluwagbamigbe Fajemiroye, Keasling Adam, Zjawiony Jordan K, Costa Elson Alves, Adeleke Adesiyan Aderoju
The search for psychoactive plants possessing therapeutic potential in the treatment of anxiety and depression has attracted growing interest. One such plant, Nymphaea lotus (commonly known as water lily), is used in traditional medicine for analgesic and sedative effects. The present study sought to assess the anti-anxiety and antidepressant activities of crude leaf extract of N. lotus and determine possible mechanisms of action. Barbiturate sleep induction, rota-rod, light/dark box, elevated plus maze, forced swimming test (FST) and open field test (OFT) were conducted...
2018: Iranian Journal of Pharmaceutical Research: IJPR
Zhenyu Zhang, Lihui Cheng, Ru Wang, Ying Cen, Zhengyong Li
Background: Triamcinolone acetonide (TAC) is used frequently in the treatment of keloid scars, but has presented controversial results. In this study, we aim to evaluate the effectiveness of TAC compared with other common therapies used in keloid treatment. Methods: MEDLINE, Embase, Web of Science and the Cochrane Library databases were searched until January 2018. Key data were extracted from eligible randomized controlled trials. Both pairwise and network meta-analyses were conducted for synthesizing data from eligible studies...
2018: Therapeutics and Clinical Risk Management
Kaitlin Krebs, Chris Rorden, X Michelle Androulakis
OBJECTIVE: In this pilot study, the purpose is to investigate if a series of sphenopalatine ganglion (SPG) blockade treatments modulate the functional connectivity within the salience and central executive network (CEN) in chronic migraine with medication overuse headaches (CMw/MOH ). BACKGROUND: Using intranasal local anesthesia to block the SPG for the treatment of various headache disorders has been employed in clinical practice since the early 1900s. However, the exact mechanism of how SPG modulate resting state intrinsic functional brain networks connectivity remains to be elucidated...
May 2018: Headache
Jonathan A Odukoya, Segun I Popoola, Aderemi A Atayero, David O Omole, Joke A Badejo, Temitope M John, Olalekan O Olowo
In Nigerian universities, enrolment into any engineering undergraduate program requires that the minimum entry criteria established by the National Universities Commission (NUC) must be satisfied. Candidates seeking admission to study engineering discipline must have reached a predetermined entry age and met the cut-off marks set for Senior School Certificate Examination (SSCE), Unified Tertiary Matriculation Examination (UTME), and the post-UTME screening. However, limited effort has been made to show that these entry requirements eventually guarantee successful academic performance in engineering programs because the data required for such validation are not readily available...
April 2018: Data in Brief
Segun I Popoola, Aderemi A Atayero, Joke A Badejo, Temitope M John, Jonathan A Odukoya, David O Omole
Empirical measurement, monitoring, analysis, and reporting of learning outcomes in higher institutions of developing countries may lead to sustainable education in the region. In this data article, data about the academic performances of undergraduates that studied engineering programs at Covenant University, Nigeria are presented and analyzed. A total population sample of 1841 undergraduates that studied Chemical Engineering (CHE), Civil Engineering (CVE), Computer Engineering (CEN), Electrical and Electronics Engineering (EEE), Information and Communication Engineering (ICE), Mechanical Engineering (MEE), and Petroleum Engineering (PET) within the year range of 2002-2014 are randomly selected...
April 2018: Data in Brief
Running Niu, Du Lei, Fuqin Chen, Ying Chen, Xueling Suo, Lingjiang Li, Su Lui, Xiaoqi Huang, John A Sweeney, Qiyong Gong
Introduction: Disrupted topological organization of brain functional networks has been widely observed in posttraumatic stress disorder (PTSD). However, the topological organization of the brain grey matter (GM) network has not yet been investigated in pediatric PTSD who was more vulnerable to develop PTSD when exposed to stress. Materials and methods: Twenty two pediatric PTSD patients and 22 matched trauma-exposed controls who survived a massive earthquake (8...
2018: NeuroImage: Clinical
Tun Cao, Chen-Wei Wei, Meng-Jia Cen, Bao Guo, Yong-June Kim, Shuang Zhang, Cheng-Wei Qiu
The transformation optics (TO) technique, which establishes an equivalence between a curved space and a spatial distribution of inhomogeneous constitutive parameters, has enabled an extraordinary paradigm for manipulating wave propagation. However, extreme constitutive parameters, as well as a static nature, inherently limit the simultaneous achievement of broadband performance, ultrafast reconfigurability and versatile reprogrammable functions. Here, we integrate the TO technique with an active phase-change chalcogenide to achieve a reconfigurable multi-mode guided-wave lens...
June 5, 2018: Nanoscale
Mahmud A Muminov, Liyue Guo, Yanjie Song, Xian Gu, Yu Cen, Jie Meng, Gaoming Jiang
This study compared the impacts of different weed managements on weed community, soil health and economic performance between the wheat-maize (WM) and garlic-soybean (GS) rotations. A total of four treatments (H0 T, tillage without herbicide; H0 T0 , without both herbicide and tillage; HT, both herbicide and tillage; HT0 , herbicide without tillage) were designed for both rotations. A total of 16 weed species were recorded in the WM rotation, with life forms of 62% for annuals, 12% for annual + perennial and 20% for perennials...
2018: PeerJ
Jieni Yao, Dawei Sun, Haiyan Cen, Haixia Xu, Haiyong Weng, Fang Yuan, Yong He
Plant responses to drought stress are complex due to various mechanisms of drought avoidance and tolerance to maintain growth. Traditional plant phenotyping methods are labor-intensive, time-consuming, and subjective. Plant phenotyping by integrating kinetic chlorophyll fluorescence with multicolor fluorescence imaging can acquire plant morphological, physiological, and pathological traits related to photosynthesis as well as its secondary metabolites, which will provide a new means to promote the progress of breeding for drought tolerant accessions and gain economic benefit for global agriculture production...
2018: Frontiers in Plant Science
Xia-An Bi, Junxia Zhao, Qian Xu, Qi Sun, Zhigang Wang
Some functional magnetic resonance imaging (fMRI) researches in autism spectrum disorder (ASD) patients have shown that ASD patients have significant impairment in brain response. However, few researchers have studied the functional structure changes of the eight resting state networks (RSNs) in ASD patients. Therefore, research on statistical differences of RSNs between 42 healthy controls (HC) and 50 ASD patients has been studied using linear independent component analysis (ICA) in this paper. Our researches showed that there was abnormal functional connectivity (FC) of RSNs in ASD patients...
2018: Frontiers in Physiology
Xiaoyun Guo, Yu Cen, Jiaxu Wang, Haixing Jiang
Liver fibrosis is a typical complication of chronic liver diseases resulting in cirrhosis that remains a major public health problem. The aim of the present study was to identify the role of interleukin-9 (IL-9), an important regulator of inflammation and autoimmune diseases, in hepatic fibrosis progression. It was found that the expression of IL-9 was significantly increased in liver tissues of liver cirrhosis patients compared with that in healthy controls. Moreover, CXCL10, not CXCL9 or CXCL11, induced IL-9 expression in the liver tissue...
May 31, 2018: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
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