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https://www.readbyqxmd.com/read/29029337/protective-effect-of-indoor-residual-spraying-of-insecticide-on-preterm-birth-among-pregnant-women-with-hiv-in-uganda-a-secondary-data-analysis
#1
Michelle E Roh, Stephen Shiboski, Paul Natureeba, Abel Kakuru, Mary Muhindo, Teddy Ochieng, Albert Plenty, Catherine A Koss, Tamara D Clark, Patricia Awori, Miriam Nakalambe, Deborah Cohan, Prasanna Jagannathan, Roly Gosling, Diane V Havlir, Moses R Kamya, Grant Dorsey
Background: Recent evidence demonstrated improved birth outcomes among HIV-uninfected pregnant women protected by indoor residual spraying of insecticide (IRS). Evidence regarding its impact on HIV-infected pregnant women is lacking. Methods: Data were pooled from two studies conducted before-and-after an IRS campaign in Tororo, Uganda among HIV-infected pregnant women who received bednets, daily trimethoprim-sulfamethoxazole (TMP-SMX), and combination antiretroviral therapy (c-ART) at enrollment...
October 6, 2017: Journal of Infectious Diseases
https://www.readbyqxmd.com/read/29029127/antibody-kinetics-and-response-to-routine-vaccinations-in-infants-born-to-women-who-received-an-investigational-trivalent-group-b-streptococcus-polysaccharide-crm197-conjugate-vaccine-during-pregnancy
#2
Shabir A Madhi, Anthonet Koen, Clare L Cutland, Lisa Jose, Niresha Govender, Frederick Wittke, Morounfolu Olugbosi, Ajoke Sobanjo-Ter Meulen, Sherryl Baker, Peter M Dull, Vas Narasimhan, Karen Slobod
Background: Maternal vaccination against group B Streptococcus (GBS) might provide protection against invasive GBS disease in infants. We investigated the kinetics of transplacentally transferred GBS serotype-specific capsular antibodies in the infants and their immune response to diphtheria toxoid and pneumococcal vaccination. Methods: This phase 1b/2, observer-blind, single-center study (NCT01193920) enrolled infants born to women previously randomized (1:1:1:1) to receive either GBS vaccine at dosages of 0...
September 23, 2017: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/29028938/impact-of-the-us-maternal-tetanus-diphtheria-and-acellular-pertussis-vaccination-program-on-preventing-pertussis-in-infants-2-months-of-age-a-case-control-evaluation
#3
Tami H Skoff, Amy E Blain, James Watt, Karen Scherzinger, Melissa McMahon, Shelley M Zansky, Kathy Kudish, Paul R Cieslak, Melissa Lewis, Nong Shang, Stacey W Martin
Background: Infants aged <1 year are at highest risk for pertussis-related morbidity and mortality. In 2012, Tdap (tetanus toxoid, reduced diphtheria toxoid, and acellular pertussis) vaccine was recommended for women during each pregnancy to protect infants in the first months of life; data on effectiveness of this strategy are currently limited. Methods: We conducted a case-control evaluation among pertussis cases <2 months old with cough onset between 1 January 2011 and 31 December 2014 from 6 US Emerging Infection Program Network states...
September 28, 2017: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/29028827/p-falciparum-infection-and-maternofetal-antibody-transfer-in-malaria-endemic-settings-of-varying-transmission
#4
Alistair R D McLean, Danielle Stanisic, Rose McGready, Kesinee Chotivanich, Caroline Clapham, Francesca Baiwog, Mupawjay Pimanpanarak, Peter Siba, Ivo Mueller, Christopher L King, François Nosten, James G Beeson, Stephen Rogerson, Julie A Simpson, Freya J I Fowkes
INTRODUCTION: During pregnancy, immunoglobulin G (IgG) is transferred from the mother to the fetus, providing protection from disease in early infancy. Plasmodium falciparum infections may reduce maternofetal antibody transfer efficiency, but mechanisms remain unclear. METHODS: Mother-cord paired serum samples collected at delivery from Papua New Guinea (PNG) and the Thailand-Myanmar Border Area (TMBA) were tested for IgG1 and IgG3 to four P. falciparum antigens and measles antigen, as well as total serum IgG...
2017: PloS One
https://www.readbyqxmd.com/read/29027769/moral-exemptions-and-accommodations-for-coverage-of-certain-preventive-services-under-the-affordable-care-act-interim-final-rules-with-request-for-comments
#5
(no author information available yet)
The United States has a long history of providing conscience protections in the regulation of health care for entities and individuals with objections based on religious beliefs or moral convictions. These interim final rules expand exemptions to protect moral convictions for certain entities and individuals whose health plans are subject to a mandate of contraceptive coverage through guidance issued pursuant to the Patient Protection and Affordable Care Act. These rules do not alter the discretion of the Health Resources and Services Administration, a component of the United States Department of Health and Human Services, to maintain the guidelines requiring contraceptive coverage where no regulatorily recognized objection exists...
October 13, 2017: Federal Register
https://www.readbyqxmd.com/read/29027768/religious-exemptions-and-accommodations-for-coverage-of-certain-preventive-services-under-the-affordable-care-act-interim-final-rules-with-request-for-comments
#6
(no author information available yet)
The United States has a long history of providing conscience protections in the regulation of health care for entities and individuals with objections based on religious beliefs and moral convictions. These interim final rules expand exemptions to protect religious beliefs for certain entities and individuals whose health plans are subject to a mandate of contraceptive coverage through guidance issued pursuant to the Patient Protection and Affordable Care Act. These rules do not alter the discretion of the Health Resources and Services Administration (HRSA), a component of the United States Department of Health and Human Services (HHS), to maintain the guidelines requiring contraceptive coverage where no regulatorily recognized objection exists...
October 13, 2017: Federal Register
https://www.readbyqxmd.com/read/29025027/maternal-melatonin-or-agomelatine-therapy-prevents-programmed-hypertension-in-male-offspring-of-mother-exposed-to-continuous-light
#7
You-Lin Tain, Yu-Ju Lin, Julie Y H Chan, Chien-Te Lee, Chien-Ning Hsu
Hypertension can originate from early-life insults, whereas maternal melatonin therapy can be protective in a variety of models of programmed hypertension. We hypothesize that melatonin or melatonin receptor agonist agomelatine can prevent programmed hypertension in adult offspring induced by maternal exposure to continuous light. Female Sprague-Dawley pregnant rats randomly divided into four groups: controls, rats exposed to continuous light, exposed to continuous light plus treated with agomelatine (50mg/day i...
September 9, 2017: Biology of Reproduction
https://www.readbyqxmd.com/read/29023968/pregnant-metaphors-and-surrogate-meanings-bringing-the-ethnography-of-pregnancy-and-surrogacy-into-conversation-in-israel-and-beyond
#8
Tsipy Ivry, Elly Teman
This article explores the way that surrogacy and normal pregnancy share cultural assumptions about pregnancy. Through a juxtaposition of our ethnographic studies of two groups of Jewish-Israeli women-women who have undergone "normal," low-risk pregnancies and women who have given birth as gestational surrogates-we argue that surrogacy and pregnancy emerge as potent metaphors for one another. Both pregnant women and surrogates divided their bodies into two separate realms: fetus and maternal pregnant body. Both trivialized the effect of gestational influence on fetal health, making the fetus seem detached from gestational capacities of the mother...
October 11, 2017: Medical Anthropology Quarterly
https://www.readbyqxmd.com/read/29023818/commentary-on-montag-et%C3%A2-al-2017-the-importance-of-cbpr-in-fasd-prevention-with-american-indian-communities
#9
Jessica D Hanson, Tess L Weber
Prenatal alcohol consumption is a public health concern due to potential lifelong physical and cognitive effects in offspring, often presenting in the form of fetal alcohol syndrome (FAS) or other fetal alcohol spectrum disorders (FASD). FASD is the continuum of lifelong outcomes in those born prenatally exposed to alcohol and includes a diagnosis of fetal alcohol syndrome (FAS), which is diagnosed through facial abnormalities, growth retardation, and delayed brain growth (Hoyme et al., 2016), as well as secondary disabilities such as conduct disorders, mental illness, and psychosocial functioning...
October 10, 2017: Alcoholism, Clinical and Experimental Research
https://www.readbyqxmd.com/read/29023770/c-c-motif-chemokine-ligand-23-abolishes-er-stress-and-lps-induced-reduction-in-proliferation-of-bovine-endometrial-epithelial-cells
#10
Whasun Lim, Hyocheol Bae, Fuller W Bazer, Gwonhwa Song
To reduce embryonic losses in domestic animals for economic production of livestock meat and milk, chemokines and their receptors are required for proper implantation and placentation during early pregnancy. In this study, we investigated the effects of C-C-motif chemokine ligand 23 (CCL23) on the proliferation of bovine endometrial (BEND) epithelial cells. CCL23 treatment improved BEND cell proliferation by enhancing PCNA and cyclin D1 expression via activation of the PI3K/AKT and MAPK signaling pathways. In addition, a combination of CCL23 and tunicamycin reversed the ER stress-induced reduction in cell proliferation and the decreased expression of UPR-mediated signaling proteins, including IRE1α, PERK, and ATF6α...
October 12, 2017: Journal of Cellular Physiology
https://www.readbyqxmd.com/read/29023747/cross-sectional-study-of-associations-between-prior%C3%A2-spontaneous-abortions-and-preterm-delivery
#11
Reza O Samani, Mohammad A Mansournia, Mahdi Sepidarkish, Amir Almasi-Hashiani, Saeid Safiri, Samira Vesali, Payam Amini, Saman Maroufizadeh
OBJECTIVE: To evaluate associations between a history of spontaneous abortion and preterm delivery during subsequent pregnancies. METHODS: The present secondary analysis included cross-sectional survey data related to all deliveries at 103 hospitals in Tehran, Iran, between July 6 and 21, 2015. Trained midwives interviewed patients within 24 hours of delivery. Adjusted odds ratios (ORs) with 95% confidence intervals (CIs) were calculated to investigate associations between spontaneous abortion and preterm delivery...
October 12, 2017: International Journal of Gynaecology and Obstetrics
https://www.readbyqxmd.com/read/29023736/an-investigation-of-fetal-behavioural-states-during-maternal-sleep-in-healthy-late-gestation-pregnancy-an-observational-study
#12
Peter R Stone, Wendy Burgess, Jordan McIntyre, Alistair J Gunn, Christopher A Lear, Laura Bennet, Edwin A Mitchell, John M D Thompson
BACKGROUND: Fetal behavioural states (FBS) are measures of fetal wellbeing. Maternal position affects FBS with supine being associated with an increased likelihood of fetal quiescence consistent with the human fetus adapting to a lower oxygen consuming state. A number of studies now confirm the association of sleep position with risk of late intrauterine death. We designed this study to observe the effects of maternal sleep positions overnight in healthy late gestation pregnancy. METHOD: Twenty nine healthy women had continuous fetal ECG recordings overnight...
October 11, 2017: Journal of Physiology
https://www.readbyqxmd.com/read/29022223/acute-kidney-injury-in-pregnancy-and-the-role-of-underlying-ckd-a-point-of-view-from-m%C3%A3-xico
#13
REVIEW
Margarita Ibarra-Hernández, Oralia Alejandra Orozco-Guillén, María Luz de la Alcantar-Vallín, Ruben Garrido-Roldan, María Patricia Jiménez-Alvarado, Kenia Benitez Castro, Francisco Villa-Villagrana, Mario Borbolla, Juan Manuel Gallardo-Gaona, Guillermo García-García, Norberto Reyes-Paredes, Giorgina Barbara Piccoli
The incidence of acute kidney injury in pregnancy (P-AKI) in developed countries is significantly lower than in developing ones, where it is estimated to range between 4 and 26%. Mortality in cases of P-AKI requiring dialysis is high, varying from 20 to 80%. In developing countries, clinical decisions are often based on the availability of services and not on needs. Prenatal surveillance in Mexico does not include serum creatinine, limiting the potential for early diagnosis of AKI and CKD and their differential diagnosis...
October 11, 2017: Journal of Nephrology
https://www.readbyqxmd.com/read/29017665/folic-acid-effect-on-artemether-induced-cardiac-anomalies-in-mice-embryos
#14
Muhammad Shahid Akhtar, Mohammad Tahir
OBJECTIVE: To determine the role of folic acid in preventing the adverse effects of artemether, on fetal heart in Albino mice. STUDY DESIGN: Experimental study. PLACE AND DURATION OF STUDY: Department of Anatomy, University of Health Sciences, Lahore, from July 2011 to January 2012. METHODOLOGY: Eighteen pregnant Albino mice were randomly divided into three groups A, B, and C of six mice each. The control group Awas treated with intramuscular injection of solvent arachis oil 10...
September 2017: Journal of the College of Physicians and Surgeons—Pakistan: JCPSP
https://www.readbyqxmd.com/read/29017513/association-between-tnf-il1b-il6-il10-and-ifng-polymorphisms-and-recurrent-miscarriage-a-case-control-study
#15
Jianting Ma, Xingguang Zhang, Gang He, Chunlin Yang
BACKGROUND: Approximately half of recurrent miscarriages have unexplained etiology. Recent evidences suggest that cytokines are important determinants in pregnancy maintenance and as such, cytokine gene polymorphisms, which can affect cytokine production and/or functionality, could play a role in the disorder. Thus, we aimed to investigate the association of selected cytokine gene polymorphisms with risk of recurrent miscarriage among Chinese. METHODS: TNF -238G > A, TNF -308G > A, IL1B -511 T > C, IL1B 3954C > T, IL6 -174G > C, IL6 -634C > G, IL10 -1082A > G and IFNG 874A > T polymorphisms were genotyped on 775 women with idiopathic recurrent miscarriage and 805 healthy parous control women...
October 10, 2017: Reproductive Biology and Endocrinology: RB&E
https://www.readbyqxmd.com/read/29017419/effect-of-normal-pregnancy-followed-by-lactation-on-long-term-maternal-health-in-a-mouse-model
#16
Egle Bytautiene Prewit, Talar Kechichian, Deborah Okunade, Huaizhi Yin, Alison M Stuebe
Although it has been widely accepted that pregnancies with complications are associated with increased maternal cardiovascular risk later in life, there is no consensus if noncomplicated pregnancy followed by lactation plays a protective role or is a risk factor. The objective of this study was to investigate the effects of normal pregnancy and lactation on long-term maternal health in a mouse model. CD-1 mice were allocated to breeding (primigravid [PG]) and nonbreeding (nulligravid [NG]) groups. The PG group proceeded through normal pregnancy and delivery...
January 1, 2017: Reproductive Sciences
https://www.readbyqxmd.com/read/29016506/contraception-and-conception-after-bariatric-surgery
#17
Marie N Menke, Wendy C King, Gretchen E White, Gabriella G Gosman, Anita P Courcoulas, Gregory F Dakin, David R Flum, Molly J Orcutt, Alfons Pomp, Walter J Pories, Jonathan Q Purnell, Kristine J Steffen, Bruce M Wolfe, Susan Z Yanovski
OBJECTIVE: To examine contraceptive practices and conception rates after bariatric surgery. METHODS: The Longitudinal Assessment of Bariatric Surgery-2 is a multicenter, prospective cohort study of adults undergoing first-time bariatric surgery as part of routine clinical care at 10 U.S. hospitals. Recruitment occurred between 2005 and 2009. Participants completed preoperative and annual postsurgical assessments for up to 7 years until January 2015. This report was restricted to women 18-44 years old with no history of menopause, hysterectomy, or estrogen and progesterone therapy...
October 6, 2017: Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28994563/an-update-on-the-genetics-of-pre-eclampsia
#18
Andee Agius, Roberta Sultana, Christian Camenzuli, Jean Calleja-Agius, Rena Balzan
Pre-eclampsia is a progressive multisystem disorder that is exclusive to human pregnancy and defined as new hypertension presenting after 20 weeks with significant proteinuria. It is a multifactorial condition with a strong genetic component and several genes have been linked with this disorder. The main players implicated in the pathogenesis of preeclampsia include immune maladaptation, haemodynamics, endothelial function, thrombophilic disorders, oxidative stress and lipid metabolism. All of these mechanisms encompass genetic factors that might be responsible for the pathogenic changes taking place...
October 9, 2017: Minerva Ginecologica
https://www.readbyqxmd.com/read/28994115/the-effect-of-fertility-treatment-on-adverse-perinatal-outcomes-in-women-aged-at-least-40-years
#19
Avi Harlev, Asnat Walfisch, Eynan Oran, Iris Har-Vardi, Michael Friger, Eitan Lunenfeld, Eliahu Levitas
OBJECTIVE: To compare perinatal outcomes between spontaneous conception and assisted reproductive technologies (ART) among patients of advanced maternal age. METHODS: The present retrospective study included data from singleton pregnancies of women aged at least 40 years who delivered between January 1, 1991, and December 31, 2013, at Soroka University Medical Center, Beer Sheva, Israel. Demographic, obstetric, and perinatal data were compared between pregnancies conceived with ART (in vitro fertilization [IVF] or ovulation induction) and those conceived spontaneously...
October 10, 2017: International Journal of Gynaecology and Obstetrics
https://www.readbyqxmd.com/read/28994111/retrospective-study-of-the-effect-of-remifentanil-use-during-labor-on-fetal-heart-rate-patterns
#20
Danne Boterenbrood, Martine M Wassen, Gerard H A Visser, Jan G Nijhuis
OBJECTIVE: To investigate possible associations between remifentanil and the appearance of sinusoidal heart rate patterns in fetuses, and neonatal outcomes. METHODS: The present retrospective cohort study included data from patients at over 37 weeks of singleton or multiple pregnancies attending Zuyderland Medical Center, Sittard, the Netherlands, in labor between June 1, and August 31, 2015. Patient data were stratified by whether remifentanil was administered during delivery (remifentanil group) or not (control group), and fetal heart rate tracings were reviewed to identify sinusoidal heart rate patterns...
October 10, 2017: International Journal of Gynaecology and Obstetrics
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