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https://www.readbyqxmd.com/read/28642638/laparoscopic-surgery-for-focal-adenomyosis
#1
Jae-Young Kwack, Yong-Soon Kwon
BACKGROUND AND OBJECTIVES: For conservative surgical treatment of focal uterine adenomyosis, laparoscopic adenomyomectomy has been increasingly performed, so that reassessment to determine the safety and efficacy of the laparoscopic surgical technique in a larger number of cases and reevaluation for reproducibility for laparoscopic adenomyomectomy is needed. We evaluate the clinical outcomes of laparoscopic adenomyomectomy with transient occlusion of uterine arteries (TOUA) for focal uterine adenomyosis performed by a single surgeon at a single institute...
April 2017: JSLS: Journal of the Society of Laparoendoscopic Surgeons
https://www.readbyqxmd.com/read/28639570/menorrhagia-and-uterine-volume-associated-with-lower-urinary-tract-symptoms-in-patients-with-adenomyosis
#2
Ting Li, Xiao-Xuan Xu, Yi Dai, Jun-Ji Zhang, Jing-He Lang, Jin-Hua Leng
BACKGROUND: Adenomyosis is a gynecological disorder with symptoms most presenting as dysmenorrhea and heavy menstrual bleeding. However, the presence of lower urinary tract symptoms (LUTS) among women with adenomyosis remains unclear. This study was designed to determine the prevalence of LUTS and factors related to the severity of these symptoms in this population. METHODS: From July 2016 to November 2016, a total of 298 untreated symptomatic adenomyosis patients and 280 age-matched controls were enrolled...
July 5, 2017: Chinese Medical Journal
https://www.readbyqxmd.com/read/28631712/-the-molecular-mechanisms-and-morphological-manifestations-of-leiomyoma-reduction-induced-by-selective-progesterone-receptor-modulators
#3
T A Demura, Z V Revazova, E A Kogan, L V Adamyan
AIM: to investigate the molecular mechanisms and morphological substrate of reduced uterine leiomyoma in patients receiving the selective progesterone receptor modulator (SPRM) ulipristal acetate for 3 months, by estimating the immunohistochemical expression of the markers steroid receptor coactivator 1 (SRC-1), nuclear receptor corepressor 1 (NCoR-1), ER, PgR, Ki-67, p16, TGF-β, and VEGF in tumor tissue. SUBJECTS AND METHODS: The investigation enrolled 75 women with uterine leiomyoma, menorrhagias, and anemia...
2017: Arkhiv Patologii
https://www.readbyqxmd.com/read/28605952/migration-of-contraceptive-implant-into-the-left-pulmonary-arterial-system
#4
Ee Phui Kew, Eshan Senanayake, Madava Djearaman, Ehab Bishay
An 18-year-old woman had an etonogestrel implant inserted into her left upper arm 2 years earlier for menorrhagia. Her symptoms were not well controlled and she requested the implant to be removed. However, clinicians were unable to locate the implant on her left arm. Computed tomography showed that the implant had migrated to a sub-lobar branch of the left lower lobe pulmonary artery. The long-term effect of leaving an etonogestrel implant in the pulmonary arterial system is unknown. This report adds to the small body of evidence on intravascular migration of a subdermally placed contraceptive implant...
January 1, 2017: Asian Cardiovascular & Thoracic Annals
https://www.readbyqxmd.com/read/28583924/congenital-hypofibrinogenaemia-a-presymptomatic-detection-of-an-extremely-rare-bleeding-disorder-in-preterm-twins
#5
Catherine Mary Breen, Muhammad I Riazat, Naomi McCallion, Michael A Boyle
Twenty-eight-week-old preterm monochorionic-diamniotic twins were admitted to the neonatal intensive care unit secondary to low birth weight and mild respiratory distress syndrome. A low fibrinogen level of less than 0.5 g/L was detected following an abnormal full blood count. They required fibrinogen transfusions until 32 weeks corrected gestation to maintain adequate fibrinogen levels. Parental screening revealed that their mother had a previously undiagnosed hypofibrinogenaemia. Of note, her only symptom was menorrhagia...
June 5, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28578202/management-of-atypical-polypoid-adenomyomas-a-case-series
#6
Grigoris F Grimbizis, Themistoklis Mikos, Dimosthenis Miliaras, George Kioussis, Theodoros D Theodoridis, Dimitrios Tsolakidis, Basil C Tarlatzis
OBJECTIVE: Atypical polypoid adenomyomas (APAs) are endometrial, non-malignant, focal, and non-invasive lesions that are intriguing for their histological resemblence to invasive endometrioid adenocarcinoma or malignant mixed Müllerian tumor. The aim of this study was to present our clinical experience, regarding the reproductive outcome, the recurrence rate, and the association with hyperplasia and cancer, in a small series of patients with APA. STUDY DESIGN: Retrospective case series of patients treated for APA in a single private hospital setting from 1998 to 2016...
May 22, 2017: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/28553555/magnetic-resonance-imaging-guided-focused-ultrasound-surgery-for-the-treatment-of-symptomatic-uterine-fibroids
#7
Laura Geraci, Alessandro Napoli, Carlo Catalano, Massimo Midiri, Cesare Gagliardo
Uterine fibroids, the most common benign tumor in women of childbearing age, may cause symptoms including pelvic pain, menorrhagia, dysmenorrhea, pressure, urinary symptoms, and infertility. Various approaches are available to treat symptomatic uterine fibroids. Magnetic Resonance-guided Focused Ultrasound Surgery (MRgFUS) represents a recently introduced noninvasive safe and effective technique that can be performed without general anesthesia, in an outpatient setting. We review the principles of MRgFUS, describing patient selection criteria for the treatments performed at our center and we present a series of five selected patients with symptomatic uterine fibroids treated with this not yet widely known technique, showing its efficacy in symptom improvement and fibroid volume reduction...
2017: Case Reports in Radiology
https://www.readbyqxmd.com/read/28546669/prevalence-clinical-and-laparoscopic-features-of-endometriosis-among-infertile-women
#8
Vineet V Mishra, Pradeep Bandwal, Ritu Agarwal, Rohina Aggarwal
OBJECTIVE: To study the prevalence, clinical and laparoscopic characteristics of endometriosis in infertile women. STUDY DESIGN: This is a hospital-based prospective study. PATIENTS: Five hundred and two (502) patients underwent diagnostic laparoscopy for evaluation of cause for infertility. Staging of endometriosis was done according to the rAFS scoring system. RESULTS: Out of 502 women, 276 (54.98 %) showed the presence of endometriosis, while 226 (45...
June 2017: Journal of Obstetrics and Gynaecology of India
https://www.readbyqxmd.com/read/28546238/persistent-fetal-lobulation-of-kidney-mimicking-renal-tumour
#9
Syed Muhammad Nazim, Muhibullah Bangash, Basit Salam
Renal pseudotumour is a term coined to describe conditions of renal anatomic variants that simulate focal renal pathology like a tumour on ultrasonography. These include persistent fetal lobulation, hypertrophy of Bertin columns and dromedary humps. We report a case of a 30-year-old nulliparous woman who was managed in gynaecology clinic for menorrhagia and was subsequently referred to us for management of recurrent urinary tract infections. The clinical examination was normal and on ultrasound scan, she was found to have multiple enlarged heterogeneous solid masses in both kidneys with significantly increased vascularity, suspicious for neoplastic lesions...
May 24, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28544260/hysteroscopic-excision-of-symptomatic-myometrial-adenomyosis-feasibility-and-effectiveness
#10
W Xia, D Zhang, Q Zhu, H Zhang, S Yang, J Ma, H Pan, T Tong, J Sun, J Zhang
OBJECTIVE: To explore the feasibility and efficacy of hysteroscopic excision of myometrial adenomyotic lesions. DESIGN: A case-series study. SETTING: A university medical centre. POPULATION: 51 women with myometrial adenomyosis completed the study. METHODS: The patients underwent hysteroscopic excision of myometrial adenomyosis and were followed up for 24 months. The degree of symptoms, uterine volume, and serum CA125 concentrations were recorded...
May 19, 2017: BJOG: An International Journal of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/28544019/let-s-talk-period-preliminary-results-of-an-online-bleeding-awareness-knowledge-translation-project-and-bleeding-assessment-tool-promoted-on-social-media
#11
E Reynen, J Grabell, A K Ellis, P James
INTRODUCTION: Undiagnosed bleeding disorders are common and can pose significant health risks, especially for women. Recently, a self-administered bleeding assessment tool (Self-BAT) was validated in von Willebrand disease. AIM: To increase awareness of undiagnosed bleeding disorders through the use of an informational website (http://letstalkperiod.ca) targeted at women in their reproductive years. METHODS: The Let's Talk Period website was built in consultation with a medical communications company and focus groups of women, with the aim of clearly presenting key messages around menstrual bleeding...
May 24, 2017: Haemophilia: the Official Journal of the World Federation of Hemophilia
https://www.readbyqxmd.com/read/28511462/story-of-a-giant-endometrial-polyp-in-asymptomatic-postmenopausal-female
#12
Jahnavi Meena, Rahul Manchanda, Sudhir Kulkarni, Nirmal Bhargava, Priyanka Mahawar
Endometrial polyps are localized overgrowth of endometrial glands and stoma through the uterine cavity. They are associated with postmenopausal bleeding, infertility and menorrhagia and are affected by unbalanced oestrogen therapy or increased frequency of tamoxifen exposure. We report a case of giant endometrial polyp in postmenopausal female without vaginal bleeding and hormone or drug use. A 65-year-old, postmenopausal female P3L2 with hypertension and Diabetes Mellitus (DM) came for routine health check-up...
March 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28494324/an-unexpected-diagnosis-of-primary-omental-endometrial-stromal-sarcoma-in-a-patient-with-acute-right-abdominal-pain-a-case-report-and-review-of-literature
#13
Vered Buchholz, George Kiroff, Markus Trochsler, Harsh Kanhere
INTRODUCTION: Extrauterine Endometrial Stromal Sarcoma (EESS) is an extremely rare mesenchymal tumour that simulates other pathologies, and therefore poses a diagnostic challenge. This report outlines a case of EESS arising from the greater omentum mimicking a colonic tumour, with review of literature. PRESENTATION OF CASE: A 47-year-old woman, with history of hysterectomy for menorrhagia and hormone replacement therapy (HRT), presented with right sided abdominal pain and localized peritonism...
2017: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/28487769/ferric-carboxymaltose-as-treatment-in-women-with-iron-deficiency-anemia
#14
Melvin H Seid, Angelia D Butcher, Ashwin Chatwani
Objective. To evaluate safety and efficacy of intravenous ferric carboxymaltose (FCM) versus standard medical care (SMC) for iron-deficiency anemia (IDA) in postpartum women and women with heavy menstrual bleeding. Study Design. This open-label, multicenter study randomized women with IDA (hemoglobin ≤ 11.0 g/dL) to single doses of FCM (15 mg/kg [maximum 1000 mg]) or SMC (this treatment was determined by the investigator and there may have been no treatment). Safety data (primary outcome) were collected for 30 days...
2017: Anemia
https://www.readbyqxmd.com/read/28458475/ormeloxifene-looking-beyond-contraception
#15
Tapasi Pati, Kabita Chanania, Satyabhama Marandi, Jagadish Hansa
AIMS: This study is aimed at finding out a logical solution for perimenopausal menorrhagia in normal or bulky uterus. SETTINGS AND DESIGN: The study is carried out at a tertiary care hospital at Odisha. In our setup, nearly 900 hysterectomies are done per year out of which 60% are for menorrhagia with bulky uterus. SUBJECTS AND METHODS: There were sixty cases of menorrhagia between the ages of 40 and 55 years who completed child bearing treated with ormeloxifene...
January 2017: Journal of Mid-life Health
https://www.readbyqxmd.com/read/28447100/f7-gene-variants-modulate-protein-levels-in-a-large-cohort-of-patients-with-factor-vii-deficiency-results-from-a-genotype-phenotype-study
#16
Gabriele Quintavalle, Federica Riccardi, Gianna Franca Rivolta, Davide Martorana, Caterina Di Perna, Antonio Percesepe, Annarita Tagliaferri
Congenital factor VII (FVII) deficiency is a rare bleeding disorder caused by mutations in F7 gene with autosomal recessive inheritance. A clinical heterogeneity with poor correlation with FVII:C levels has been described. It was the objective of this study to identify genetic defects and to evaluate their relationships with phenotype in a large cohort of patients with FVII:C<50 %. One hundred twenty-three probands were genotyped for F7 mutations and three polymorphic variants and classified according to recently published clinical scores...
April 27, 2017: Thrombosis and Haemostasis
https://www.readbyqxmd.com/read/28437003/high-intensity-focused-ultrasound-for-the-treatment-of-adenomyosis-selection-criteria-efficacy-safety-and-fertility
#17
Lian Zhang, Fangwen Rao, Raymond Setzen
Adenomyosis is a disorder of uterus in which endometrial glands and stroma are present within the uterine musculature. The main clinical manifestations are dysmenorrhea and menorrhagia. Adenomyosis has a great impact on both the quality of life and fertility of women. The treatment of adenomyosis remains an immense challenge MATERIAL AND METHODS: Relevant articles were searched through MEDLINE, Pubmed between 2000 and March 2017. The search terms of adenomyosis, magnetic resonance imaging (MRI) features of adenomyosis, high intensity focused ultrasound (HIFU), Ultrasound-guided HIFU and MRgFUS were used...
April 24, 2017: Acta Obstetricia et Gynecologica Scandinavica
https://www.readbyqxmd.com/read/28418720/effectiveness-and-outcomes-of-thermablate-endometrial-ablation-system-in-women-with-heavy-menstrual-bleeding
#18
Ghadeer Al-Shaikh, Ghada Almalki, Mujahed Bukhari, Amel Fayed, Hazem Al-Mandeel
Heavy menstrual bleeding (HMB) is a common problem in women of reproductive age group with major impact on their quality of life (QoL). The aim was to study the short-term effectiveness of Thermablate Endometrial Ablation System (EAS) and its impact on QoL in women with HMB. This was a prospective cohort study conducted on consecutive 72 women suffering from HMB. The success rate was estimated and patients' QoL was compared before and after the procedure using the Aberdeen menorrhagia severity scale. The mean follow-up period was 18 months (6-24 months)...
April 18, 2017: Journal of Obstetrics and Gynaecology: the Journal of the Institute of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/28416932/assessment-of-endometrial-sampling-and-histopathological-results-analysis-of-4-247-cases
#19
Zeynep Ozturk Inal, Hasan Ali Inal, Ilknur Kucukosmanoglu, Hasan Kucukkendirci
OBJECTIVE: This study aimed to investigate the relationship between indications and histopathological results in patients undergoing endometrial sampling. MATERIALS AND METHODS: Data of 4,247 patients undergoing endometrial sampling due to non-obstetric gynecological causes between January 2010 and October 2016 were retrospectively evaluated using the archives of the Gynecology and Obstetrics Clinic of Konya Training and Research Hospital. RESULTS: The mean age of patients was 46...
February 2017: Eurasian Journal of Medicine
https://www.readbyqxmd.com/read/28411085/vaginal-myomectomy-using-d%C3%A3-hrssen-longitudinal-median-cervical-incision-a-case-series-of-19-patients
#20
Wai Yoong, Wei Zhao, Hong Cai, Robyn D'Cruz, Alessia Corrieri, John Hamilton, Abiodun Fakokunde
STUDY OBJECTIVE: To examine demographics and outcome measures of women having undergone vaginal excision of myoma through Dührssen (longitudinal median cervical) incision DESIGN: Prospective case series DESIGN CLASSIFICATION: The design of the study conforms to Canadian Task Force II3 ie evidence from timed series SETTING: A London teaching hospital PATIENTS: 19 patients with either a) submucus myoma (type 1) located near the cervix or b) pedunculated intracavity myoma (type 0), excised via Dührssen incision INTERVENTIONS: Dührssen (median longitudinal) incision on the anterior or posterior cervical lip MEASUREMENTS: Duration of procedure, intraoperative complications, estimated blood loss, length of stay, % 24 hour discharge, readmission rates RESULTS: Between 2009-16, 19 women had their myomas (submucus type 1, n=17; pedunculated intracavity type 0, n=2) removed vaginally via Dührssen incision...
April 11, 2017: Journal of Minimally Invasive Gynecology
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