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Abnormal uterine bleeding

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https://www.readbyqxmd.com/read/29657247/protective-effect-of-taohong-siwu-decoction-on-abnormal-uterine-bleeding-induced-by-incomplete-medical-abortion-in-rats-during-early-pregnancy
#1
Yanyan Zhang, Jichen Wang, Chijing Zuo, Weidong Chen, Qian Zhu, Dongdong Guo, Huanru Wu, Huizhuo Wang, Daiyin Peng, Lan Han
Abnormal uterine bleeding (AUB) induced by incomplete abortion is a common gynecological disease. Taohong Siwu decoction (TSD) is a traditional Chinese medicine (TCM) formula, which has been developed to treat AUB for hundreds of years. In this study, rats had incomplete abortion induced in early pregnancy using mifepristone and misoprostol. The duration and quantity of uterine bleeding were recorded and measured. The pathologic histologic grade was evaluated by hematoxylin-eosin staining (HE). Estradiol (E2 ) and progesterone (P) levels were measured by enzyme linked immunosorbent assays (ELISA)...
April 14, 2018: Chemical & Pharmaceutical Bulletin
https://www.readbyqxmd.com/read/29628726/abnormal-uterine-bleeding-evaluation-by-endometrial-aspiration
#2
Pratibha Singh
Endometrial evaluation is generally indicated in cases presenting with abnormal uterine bleeding (AUB), especially in women more than 35 years of age. AUB encompasses a variety of presentation, for example, heavy menstrual bleeding, frequent bleeding, irregular vaginal bleeding, postcoital and postmenopausal bleeding to name a few. Many methods are used for the evaluation of such cases, with most common being sonography and endometrial biopsy with very few cases requiring more invasive approach like hysteroscopy...
January 2018: Journal of Mid-life Health
https://www.readbyqxmd.com/read/29611018/the-who-what-why-and-when-of-gynaecological-referrals-for-refugee-women
#3
Sarah L Silverberg, Lacey Harding, Rachel F Spitzer, Meb Rashid
Refugees have health needs relating to unstable living situations and poor access to care. We examined the nature of health problems requiring gynaecological referrals for refugee women in Toronto. A retrospective cohort design was used to examine gynaecologic referrals of women at a refugee clinic between December, 2011 and June, 2016. The primary outcome measure was the indications for gynaecological referral. 125 out of 1040 women received a gynaecologic referral for 131 unique concerns. The most common referrals were for abnormal uterine bleeding and cervical dysplasia...
April 2, 2018: Journal of Immigrant and Minority Health
https://www.readbyqxmd.com/read/29607236/a-case-of-primary-uterina-lymphoma-presenting-with-bleeding-pelvic-pain-and-dysmenorrhea
#4
Lilian Yukari Miura, Miriam Anyury Daquin Maure, Monica Tessmann Zomer, Reitan Ribeiro, Teresa Cristina Santos Cavalcanti, William Kondo
Primary non-Hodgkin's lymphoma (NHL) can arise from lymphatic cells located in solid organs (extranodal) and it accounts for 25 to 35% of all NHL. Primary lymphoma on the female genital tract (PLFGT) is a rare disease, comprising 0.2 to 1.1% of all extranodal lymphomas in the female population. In this paper, the authors report an extremely rare case of a 48-year-old woman who exhibited an abnormal uterine bleeding, pelvic pain, and dysmenorrhea history. The transvaginal ultrasound showed an anteverted uterus measuring 153 cm3 in volume, with intramural leiomyomas...
2018: Case Reports in Obstetrics and Gynecology
https://www.readbyqxmd.com/read/29606892/management-of-abnormal-uterine-bleeding-focus-on-ambulatory-hysteroscopy
#5
REVIEW
Shilpa Kolhe
The rapid evolution in ambulatory hysteroscopy (AH) has transformed the approach to diagnose and manage abnormal uterine bleeding (AUB). The medical management in primary care remains the mainstay for initial treatment of this common presentation; however, many women are referred to secondary care for further evaluation. To confirm the diagnosis of suspected intrauterine pathology, the traditional diagnostic tool of day case hysteroscopy and dilatation and curettage in a hospital setting under general anesthesia is now no longer required...
2018: International Journal of Women's Health
https://www.readbyqxmd.com/read/29604475/robotic-assisted-laparoscopic-cervicovaginal-myomectomy
#6
Pouya Javadian, Alexander Juusela, Farr Nezhat
STUDY OBJECTIVE: To illustrate a robotic assisted laparoscopic resection for the cervicovaginal myomectomy. DESIGN: Step-wise instruction using video. Case report (Canadian Task Force classification III). SETTING: A tertiary referral center in New York, NY, USA. A 39-year-old woman G0, (body mass index of 23.0 kg/m2 ) with known cervicovaginal fibroid which in the past underwent uterine artery embolization, presented with recurrence of her severe abnormal vaginal bleeding...
March 28, 2018: Journal of Minimally Invasive Gynecology
https://www.readbyqxmd.com/read/29604099/evaluation-of-complete-blood-count-parameters-to-predict-endometrial-cancer
#7
Cigdem Yayla Abide, Evrim Bostanci Ergen, Ebru Cogendez, Cetin Kilicci, Faik Uzun, Enis Ozkaya, Ates Karateke
BACKGROUND: Complete blood count parameters have been introduced to be diagnostic biomarkers for many cancer-related diseases associated with inflammatory process. The aim of our study was to detect whether there is any relationship between benign or malignant endometrial pathologies and complete blood count parameters. METHODS: Four hundred and sixteen patients with a complaint of abnormal uterine bleeding who admitted to Zeynep Kamil Women and Children's Health Training and Research hospital between 2013 and 2016 and undergoing endometrial biopsy were included in the study...
March 31, 2018: Journal of Clinical Laboratory Analysis
https://www.readbyqxmd.com/read/29593995/late-onset-endometrial-ablation-failure
#8
REVIEW
Morris Wortman
Endometrial ablation, first reported in the 19th century, has gained wide acceptance in the gynecologic community as an important tool for the management of abnormal uterine bleeding when medical management has been unsuccessful or contraindicated. The introduction of global endometrial ablation (GEA) devices beginning in 1997 has provided unsurpassed safety addressing many of the concerns associated with their resectoscopic predecessors. As of this writing the GEA market has surpassed a half-million devices in the United States per annum and has an expected compound annual growth rate (CAGR) projected to be 5...
July 2017: Case Reports in Women's Health
https://www.readbyqxmd.com/read/29592997/cornual-ectopic-pregnancy-laparoscopic-management-step-by-step
#9
Neha Varun, Aruna Nigam, Arifa Anwar Elahi, Abhinav Jain
Cornual (interstitial) ectopic pregnancy is an uncommon type of ectopic pregnancy which is located in the interstitial part of the fallopian tube. It accounts for 2%-4% of all ectopic pregnancies. Cornual pregnancies often pose a diagnostic and therapeutic challenge with a significant high morbidity and mortality as a result of massive intraperitoneal bleeding. A case of unruptured cornual ectopic pregnancy in a patient with abnormal uterine bleeding is reported which was successfully managed laparoscopically...
March 28, 2018: BMJ Case Reports
https://www.readbyqxmd.com/read/29570003/economic-evaluation-of-global-endometrial-ablation-versus-inpatient-and-outpatient-hysterectomy-for-treatment-of-abnormal-uterine-bleeding-us-commercial-and-medicaid-payer-perspectives
#10
Jeffrey D Miller, Machaon M Bonafede, Qian Cai, Scott K Pohlman, Kathleen A Troeger, Aarathi Cholkeri-Singh
Every year, abnormal uterine bleeding (AUB) exacts a heavy toll on women's health and leads to high costs for the US health care system. The literature shows that endometrial ablation results in fewer complications, shorter recovery and lower costs than more commonly performed hysterectomy procedures. The objective of this study was to model clinical-economic outcomes, budget impact, and cost-effectiveness of global endometrial ablation (GEA) versus outpatient hysterectomy (OPH) and inpatient hysterectomy (IPH) procedures...
March 2018: Population Health Management
https://www.readbyqxmd.com/read/29568523/blood-microvasculature-and-lymphatic-densities-in-endometrial-polyps-and-adjacent-and-distant-endometrium
#11
Njume Peter Nijkang, Lyndal Anderson, Robert Markham, Ian Stewart Fraser, Frank Manconi
Objective: Endometrial polyps are localised growths of endometrial tissue containing glands, stroma and blood vessels, covered with epithelium. The reported prevalence of endometrial polyps is dependent upon the population being studied and the uterine imaging technique utilised. The light microscopy literature provides very little information regarding their microvasculature and lymphatic systems; however, a plethora of ultrasound data demonstrating single central arteries in most medium- or large-sized endometrial polyps are well documented...
2018: SAGE Open Medicine
https://www.readbyqxmd.com/read/29566852/role-of-medical-therapy-in-the-management-of-uterine-adenomyosis
#12
REVIEW
Silvia Vannuccini, Stefano Luisi, Claudia Tosti, Flavia Sorbi, Felice Petraglia
Adenomyosis is a benign uterine condition affecting women at various ages with different symptoms. The management of these patients is still controversial. Few clinical studies focusing on medical or surgical treatment for adenomyosis have been performed. No drug is currently labelled for adenomyosis and there are no specific guidelines to follow for the best management. Anyhow, medical treatments are effective in improving symptoms (pain, abnormal uterine bleeding and infertility). The rationale for using medical treatment is based on the pathogenetic mechanisms of adenomyosis: sex steroid hormones aberrations, impaired apoptosis, and increased inflammation...
March 2018: Fertility and Sterility
https://www.readbyqxmd.com/read/29566850/symptoms-and-classification-of-uterine-adenomyosis-including-the-place-of-hysteroscopy-in-diagnosis
#13
REVIEW
Stephan Gordts, Grigoris Grimbizis, Rudi Campo
Where histology used the presence of glands and/or stroma in the myometrium as pathognomonic for adenomyosis, imaging uses the appearance of the myometrium, the presence of striations, related to the presence of endometrial tissue within the myometrium, the presence of intramyometrial cystic structures and the size and asymmetry of the uterus to identify adenomyosis. Preliminary reports show a good correlation between the features detected by imaging and the histological findings. Symptoms associated with adenomyosis are abnormal uterine bleeding, pelvic pain (dysmenorrhea, chronic pelvic pain, dyspareunia), and impaired reproduction...
March 2018: Fertility and Sterility
https://www.readbyqxmd.com/read/29566849/pathogenesis-of-uterine-adenomyosis-invagination-or-metaplasia
#14
REVIEW
Javier García-Solares, Jacques Donnez, Olivier Donnez, Marie-Madeleine Dolmans
Adenomyosis is a commonly diagnosed estrogen-dependent gynecological disorder that causes pelvic pain, abnormal uterine bleeding, and infertility. Despite its prevalence and severity of symptoms, its pathogenesis and etiology have not yet been elucidated. The aim of this manuscript is to review the different hypotheses on the origin of adenomyotic lesions and the mechanisms involved in the evolution and progression of the disease. Two main theories have been proposed to explain the origin of adenomyosis. The most common suggests involvement of tissue injury and the repair mechanism and claims that adenomyosis results from invagination of the endometrial basalis into the myometrium...
March 2018: Fertility and Sterility
https://www.readbyqxmd.com/read/29564309/current-medical-treatment-of-uterine-fibroids
#15
REVIEW
Geum Seon Sohn, SiHyun Cho, Yong Man Kim, Chi-Heum Cho, Mee-Ran Kim, Sa Ra Lee
Uterine fibroids (leiomyomas or myomas), benign monoclonal tumors, are the most common benign tumors in women. Heavy or prolonged menstrual bleeding, abnormal uterine bleeding, resultant anemia, pelvic pain, infertility, and/or recurrent pregnancy loss are generally associated with uterine fibroids. Although curative treatment of this tumor relies on surgical therapies, medical treatments are considered the first-line treatment to preserve fertility and avoid or delay surgery. The aim of this review is to provide available and emerging medical treatment options for symptomatic uterine fibroids...
March 2018: Obstetrics & Gynecology Science
https://www.readbyqxmd.com/read/29564132/large-cell-neuroendocrine-carcinoma-arising-in-the-endometrium-a-case-report
#16
Jumpei Ogura, Yasushi Adachi, Koji Yasumoto, Akiharu Okamura, Hirofumi Nonogaki, Kazuyo Kakui, Koji Yamanoi, Koh Suginami, Takashi Koyama, Susumu Ikehara
Large-cell neuroendocrine carcinoma (LCNEC) of the endometrium is an extremely rare, high-grade malignant tumor. We herein report a case of a rapidly growing LCNEC arising in the endometrium. A 52-year-old woman was referred to Toyooka Hospital (Tooyoka, Japan) due to genital bleeding in February 2016. There had been no abnormalities on a regular gynecological and physical examination 3 months prior to the consultation. Imaging (computed tomography and magnetic resonance imaging) and a pelvic examination revealed a tumor sized 16...
April 2018: Molecular and Clinical Oncology
https://www.readbyqxmd.com/read/29549777/an-opinion-on-the-benefits-of-concomitant-oral-contraceptive-therapy-in-premenopausal-women-treated-with-oral-anticoagulants
#17
REVIEW
Richard Godin, Geneviève Roy, James Douketis
Women who are receiving an oral anticoagulant appear to be at higher risk of developing bleeding-related adverse events than men. Physiological bleeding related to the ovulatory cycle poses an ongoing risk for bleeding complications during anticoagulant therapy. Abnormal uterine bleeding and hemorrhagic ovarian cysts are risks specific to women of reproductive age who are treated with anticoagulants. The use of combined oral contraceptives can help minimize such adverse events and would also mitigate the risks of obstetrical complications related to thrombosis and anticoagulation, in addition to avoiding fetal exposure to potentially teratogenic anticoagulants...
March 8, 2018: Thrombosis Research
https://www.readbyqxmd.com/read/29541832/endometrial-ablation-normal-appearance-and-complications
#18
REVIEW
Monica R Drylewicz, Kathryn Robinson, Cary Lynn Siegel
Global endometrial ablation is a commonly performed, minimally invasive technique aimed at improving/resolving abnormal uterine bleeding and menorrhagia in women. As non-resectoscopic techniques have come into existence, endometrial ablation performance continues to increase due to accessibility and decreased requirements for operating room time and advanced technical training. The increased utilization of this method translates into increased imaging of patients who have undergone the procedure. An understanding of the expected imaging appearances of endometrial ablation using different modalities is important for the abdominal radiologist...
March 14, 2018: Abdominal Radiology
https://www.readbyqxmd.com/read/29540895/emergency-peripartum-hysterectomy-a-retrospective-study-in-a-tertiary-care-hospital-in-turkey-from-2007-to-2015
#19
Dilek Uysal, Hakan Cokmez, Cetin Aydin, Tolga Ciftpinar
Postpartum haemorrhage is the most important cause of maternal morbidity and mortality, especially when all conservative measures, including syntometrine oxytocin and Bakri balloons have failed to accomplish haemostasis and expeditious surgical procedures, such as uterine artery ligation and emergency peripartum hysterectomy (EPH) are required. This retrospective study analysed 31 cases of EPH performed between January 2007 and January 2016 in the Department of Gynecology and Obstetrics of Izmir Ataturk Teaching and Research Hospital...
March 2018: JPMA. the Journal of the Pakistan Medical Association
https://www.readbyqxmd.com/read/29537383/abnormal-uterine-bleeding-in-adolescents
#20
Selin Elmaoğulları, Zeyra Aycan
Abnormal uterine bleeding (AUB) is the major gynecologic complaint of adolescents admitting to hospital. Heavy menstrual bleeding (HMB) is the most common clinical presentation of AUB. Anovulatory cycles owing to immature hypothalamic-pituitary-ovarian axis is the leading etiology of HMB and there is an accompanying bleeding disorder in almost %20 of patients with HMB. Additionally, endocrine disorders such as hypothyroidism, hyperprolactinemia and polycystic ovary syndrome (PCOS) are possible causes of AUB...
February 28, 2018: Journal of Clinical Research in Pediatric Endocrinology
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