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https://www.readbyqxmd.com/read/28820270/second-line-treatment-options-for-pancreatic-cancer
#1
Frank C Passero, Muhammad Wasif Saif
ABTRACT Introduction: Patients with advanced pancreatic cancer (APC) refractory to first-line therapy have a dismal prognosis and limited therapeutic options, with only one option consisting of nanoliposomal irinotecan in combination with fluorouracil and folinic acid which was approved by FDA based upon results of the phase III NAPOLI-1 study. Areas covered: We performed a literature search for relevant published clinical trials, abstracts of trials in progress and ongoing or planned trials for the second line treatment of APC using Pubmed...
August 18, 2017: Expert Opinion on Pharmacotherapy
https://www.readbyqxmd.com/read/28799803/nutrition-inflammation-and-liver-spleen-axis
#2
Luigi Barrea, Carolina Di Somma, Giovanna Muscogiuri, Giovanni Tarantino, Gian Carlo Tenore, Francesco Orio, Annamaria Colao, Silvia Savastano
Chronic low-grade systemic inflammation represents a mechanism common to many diseases linked to atherosclerosis-related pathways. There is a growing body of evidence indicating that the combination of food quantity and quality along with genetic susceptibility are able to induce the aberrant activation of innate immune signalling, which initially contributes to chronic low-grade inflammation. Liver represents the central player to inflammatory response. Dietary/metabolic factors contribute to the pathogenesis of Non-alcoholic Fatty Liver Disease (NAFLD), the main causes of liver disease in the Western world...
August 11, 2017: Critical Reviews in Food Science and Nutrition
https://www.readbyqxmd.com/read/28779932/blurred-lines-emerging-practice-for-registered-dietitian-nutritionists-in-integrative-and-functional-nutrition
#3
Patricia Grace-Farfaglia, Denise L Pickett-Bernard, Andrea White Gorman, Jaleh Dehpahlavan
BACKGROUND: This study explored the health philosophy and practice orientation of RDNs in the United States. METHODS: A randomly selected group of RDNs were recruited to take an online survey using a reduced version of Integrative Medicine practice (IM-30). Confirmatory factor analysis, analyses of variance, and non-parametric tests were used to investigate the relationships between dietetic professionals' personal health philosophy, lifestyle, and orientation to Integrative Medicine...
August 2017: Complementary Therapies in Clinical Practice
https://www.readbyqxmd.com/read/28776176/white-bass-morone-chrysops-preferentially-retain-n-3-pufa-in-ova-when-fed-prepared-diets-with-varying-fa-content
#4
S Adam Fuller, Steven D Rawles, Matthew E McEntire, Troy J Bader, Marty Riche, Benjamin H Beck, Carl D Webster
We evaluated the fatty acid (FA) composition of broodstock white bass ova fed one of six commercial diets with increasing polyunsaturated FA content (n-6/n-3 ratio; 0.36, 0.39, 0.46, 0.83, 1.07, 1.12) eight weeks prior to sampling. Fatty acid profiles of ova from brooders fed each of the six diets were significantly altered according to canonical discriminant analysis. Ova FA profiles resulting from the 0.39 diet separated those from the 0.36 diet based on lower 18:2n-6 (LNA) and higher 20:1n-9 concentrations from the 0...
August 3, 2017: Lipids
https://www.readbyqxmd.com/read/28771246/diagnosis-and-treatment-of-tyrosinemia-type-i-a-us-and-canadian-consensus-group-review-and-recommendations
#5
REVIEW
Jeffrey M Chinsky, Rani Singh, Can Ficicioglu, Clara D M van Karnebeek, Markus Grompe, Grant Mitchell, Susan E Waisbren, Muge Gucsavas-Calikoglu, Melissa P Wasserstein, Katie Coakley, C Ronald Scott
Tyrosinemia type I (hepatorenal tyrosinemia, HT-1) is an autosomal recessive condition resulting in hepatic failure with comorbidities involving the renal and neurologic systems and long term risks for hepatocellular carcinoma. An effective medical treatment with 2-[2-nitro-4-trifluoromethylbenzoyl]-1,3-cyclohexanedione (NTBC) exists but requires early identification of affected children for optimal long-term results. Newborn screening (NBS) utilizing blood succinylacetone as the NBS marker is superior to observing tyrosine levels as a way of identifying neonates with HT-1...
August 3, 2017: Genetics in Medicine: Official Journal of the American College of Medical Genetics
https://www.readbyqxmd.com/read/28754198/practice-paper-of-the-academy-of-nutrition-and-dietetics-classic-and-modified-ketogenic-diets-for-treatment-of-epilepsy
#6
Kelly Roehl, Sarika L Sewak
Ketogenic diet (KD) therapy is an established form of treatment for both pediatric and adult patients with intractable epilepsy. Ketogenic diet is a term that refers to any diet therapy in which dietary composition would be expected to result in a ketogenic state of human metabolism. While historically considered a last-resort therapy, classic KDs and their modified counterparts, including the modified Atkins diet and low glycemic index treatment, are gaining ground for use across the spectrum of seizure disorders...
August 2017: Journal of the Academy of Nutrition and Dietetics
https://www.readbyqxmd.com/read/28737524/female-athlete-triad
#7
Meredith B Loveless
PURPOSE OF REVIEW: The obstetrician/gynecologist (ob/gyn) may be the first provider to have the opportunity to recognize and diagnose female athlete triad. This review will help the ob/gyn to understand the female athlete triad and what is new on this topic, how to screen and diagnose the condition and the ob/gyn's role in treatment. RECENT FINDINGS: Female athlete triad, also known as relative energy deficiency in sports, involves an interrelationship among energy availability, menstrual function and low bone density...
July 21, 2017: Current Opinion in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/28733926/perioperative-management-of-endocrine-insufficiency-after-total-pancreatectomy-for-neoplasia
#8
REVIEW
Ajay V Maker, Raashid Sheikh, Vinita Bhagia
PURPOSE: Indications for total pancreatectomy (TP) have increased, including for diffuse main duct intrapapillary mucinous neoplasms of the pancreas and malignancy; therefore, the need persists for surgeons to develop appropriate endocrine post-operative management strategies. The brittle diabetes after TP differs from type 1/2 diabetes in that patients have absolute deficiency of insulin and functional glucagon. This makes glucose management challenging, complicates recovery, and predisposes to hospital readmissions...
July 21, 2017: Langenbeck's Archives of Surgery
https://www.readbyqxmd.com/read/28731641/macronutrient-content-and-food-exchanges-for-48-greek-mediterranean-dishes
#9
Paraskevi Detopoulou, Maria Aggeli, Elena Andrioti, Maria Detopoulou
AIM: The purpose of the present study was to facilitate the translation of traditional Greek Mediterranean recipes into food exchanges for diabetes. Moreover, it provides a useful food list for meal planning, which can be used by health professionals and nutritionists, as well as researchers and the public. METHODS: A total of 48 traditional Greek Mediterranean dishes were selected in order to include appetisers, sauces, salads, pies, dishes with vegetables and legumes as well as egg, pasta, rice, meat, fish and poultry-based dishes...
April 2017: Nutrition & Dietetics: the Journal of the Dietitians Association of Australia
https://www.readbyqxmd.com/read/28718015/capable-and-credible-challenging-nutrition-science
#10
EDITORIAL
Bart Penders, Anna Wolters, Edith F Feskens, Fred Brouns, Machteld Huber, Els L M Maeckelberghe, Gerjan Navis, Theo Ockhuizen, Jogchum Plat, Jan Sikkema, Marianne Stasse-Wolthuis, Pieter van 't Veer, Marcel Verweij, Jan de Vries
Nutrition science has enriched our understanding of how to stay healthy by producing valuable knowledge about the interaction of nutrients, food, and the human body. Nutrition science also has raised societal awareness about the links between food consumption and well-being, and provided the basis for food regulations and dietary guidelines. Its collaborative and interdisciplinary research has accomplished much, scientifically and socially. Despite this, nutrition science appears to be in crisis and is currently confronted with a public reluctance to trust nutritional insights...
July 17, 2017: European Journal of Nutrition
https://www.readbyqxmd.com/read/28713814/application-of-artificial-neural-network-and-support-vector-machines-in-predicting-metabolizable-energy-in-compound-feeds-for-pigs
#11
Hamed Ahmadi, Markus Rodehutscord
BACKGROUND: In the nutrition literature, there are several reports on the use of artificial neural network (ANN) and multiple linear regression (MLR) approaches for predicting feed composition and nutritive value, while the use of support vector machines (SVM) method as a new alternative approach to MLR and ANN models is still not fully investigated. METHODS: The MLR, ANN, and SVM models were developed to predict metabolizable energy (ME) content of compound feeds for pigs based on the German energy evaluation system from analyzed contents of crude protein (CP), ether extract (EE), crude fiber (CF), and starch...
2017: Frontiers in Nutrition
https://www.readbyqxmd.com/read/28699419/chair-rise-capacity-and-associated-factors-in-older-home-care-clients
#12
Miia Tiihonen, Sirpa Hartikainen, Irma Nykänen
AIMS: The aim of this study was to investigate the ability of older home-care clients to perform the five times chair rise test and associated personal characteristics, nutritional status and functioning. METHODS: The study sample included 267 home-care clients aged ≥75 years living in Eastern and Central Finland. The home-care clients were interviewed at home by home-care nurses, nutritionists and pharmacists. The collected data contained sociodemographic factors, functional ability (Barthel Index, IADL), cognitive functioning (MMSE), nutritional status (MNA), depressive symptoms (GDS-15), medical diagnoses and drug use...
July 1, 2017: Scandinavian Journal of Public Health
https://www.readbyqxmd.com/read/28689555/implementing-a-wic-based-intervention-to-promote-exclusive-breastfeeding-challenges-facilitators-and-adaptive-strategies
#13
Johanna D Eldridge, Josette O Hartnett, Furrina F Lee, Jackson P Sekhobo, Lynn S Edmunds
OBJECTIVE: Understand factors that contributed to the implementation of a successful multicomponent intervention to promote exclusive breastfeeding (EBF) within Special Supplemental Nutrition Program for Woman, Infants, and Children (WIC) clinics. DESIGN: Qualitative study of staff implementers' experiences using implementation status reports, facilitated group discussion immediately after implementation, and WIC administrative data. SETTING: WIC staff from 12 clinics participated in an EBF Learning Community composed of 8 intervention trainings and ongoing support from trainers and peers...
July 2017: Journal of Nutrition Education and Behavior
https://www.readbyqxmd.com/read/28660672/food-allergy-response-capabilities-of-mothers-and-related-factors
#14
Satoko Aika, Misae Ito, Yachiyo Yamamoto
A parent's ability to confidently manage a child's food allergy (i.e. food allergy response capability) is considered instrumental toward treating this disorder; however, little is known regarding this measure and associated factors. A questionnaire survey among 280 qualified participants identified the greatest food allergy response capability as "spousal collaboration", followed by "elimination diet capacity", "gathering information from medical professionals", "knowledge about food allergies", and "stress coping"...
June 28, 2017: Nursing & Health Sciences
https://www.readbyqxmd.com/read/28657109/long-term-follow-up-after-bariatric-surgery-in-a-national-cohort
#15
J Thereaux, T Lesuffleur, M Païta, S Czernichow, A Basdevant, S Msika, B Millat, A Fagot-Campagna
BACKGROUND: Lifelong medical follow-up is mandatory after bariatric surgery. The aim of this study was to assess the 5-year follow-up after bariatric surgery in a nationwide cohort of patients. METHODS: All adult obese patients who had undergone primary bariatric surgery in 2009 in France were included. Data were extracted from the French national health insurance database. Medical follow-up (medical visits, micronutrient supplementation and blood tests) during the first 5 years after bariatric surgery was assessed, and compared with national and international guidelines...
September 2017: British Journal of Surgery
https://www.readbyqxmd.com/read/28652832/cognitive-behavioral-therapy-to-aid-weight-loss-in-obese-patients-current-perspectives
#16
REVIEW
Gianluca Castelnuovo, Giada Pietrabissa, Gian Mauro Manzoni, Roberto Cattivelli, Alessandro Rossi, Margherita Novelli, Giorgia Varallo, Enrico Molinari
Obesity is a chronic condition associated with risk factors for many medical complications and comorbidities such as cardiovascular diseases, some types of cancer, osteoarthritis, hypertension, dyslipidemia, hypercholesterolemia, type-2 diabetes, obstructive sleep apnea syndrome, and different psychosocial issues and psychopathological disorders. Obesity is a highly complex, multifactorial disease: genetic, biological, psychological, behavioral, familial, social, cultural, and environmental factors can influence in different ways...
2017: Psychology Research and Behavior Management
https://www.readbyqxmd.com/read/28652722/pulmonary-rehabilitation-in-copd-available-resources-and-utilization-in-swedish-primary-and-secondary-care
#17
Josefin Sundh, Helena Lindgren, Mikael Hasselgren, Scott Montgomery, Christer Janson, Björn Ställberg, Karin Lisspers
INTRODUCTION: Pulmonary rehabilitation is effective in all stages of COPD. The availability and utilization of pulmonary rehabilitation resources, and the characteristics of COPD patients receiving rehabilitation, were investigated in primary and secondary care in central Sweden. MATERIALS AND METHODS: Data on available pulmonary rehabilitation resources were collected using questionnaires, to 14 hospitals and 54 primary health care centers, and information on utilization of different rehabilitation professionals was obtained from questionnaires completed by 1,329 COPD patients from the same centers...
2017: International Journal of Chronic Obstructive Pulmonary Disease
https://www.readbyqxmd.com/read/28648264/position-of-the-academy-of-nutrition-and-dietetics-interprofessional-education-in-nutrition-as-an-essential-component-of-medical-education
#18
Lisa A Hark, Darwin Deen
It is the position of the Academy of Nutrition and Dietetics that registered dietitian nutritionists (RDNs) should play a significant role in educating medical students, residents, fellows, and physicians in practice. The more physicians learn about the effectiveness of nutrition for the prevention and treatment of noncommunicable diseases, the more likely they are to consult with RDNs and refer patients for medical nutrition therapy. The more interprofessional education that occurs between medical students, other health professional students, and RDNs, the more likely all health care professionals will understand and value the role of the RDN in improving the quality of care provided to patients...
July 2017: Journal of the Academy of Nutrition and Dietetics
https://www.readbyqxmd.com/read/28644369/european-society-for-pediatric-gastroenterology-hepatology-and-nutrition-s-educational-offer-and-the-training-syllabus
#19
Marco Maglione, Daniela Finizio, Gabor Veres, Tudor Lucian Pop, Grazia Isabella Continisio, Alexandra Papadopoulou, Alfredo Guarino
The basic knowledge necessary for a European pediatric gastroenterologist/hepatologist/nutritionist (PGHN) is set-out in the Training Syllabus (TS) of the European Society for Pediatric Gastroenterology, Hepatology, and Nutrition (ESPGHAN).We retrospectively compared the topics covered in ESPGHAN's training events between 2013 and 2016 with the basic knowledge TS items.Thirty-six initiatives including e-learning were identified. Twelve (33%) courses focused on gastroenterology, 9 (25%) on hepatology, and 10 (28%) on nutrition...
June 21, 2017: Journal of Pediatric Gastroenterology and Nutrition
https://www.readbyqxmd.com/read/28635946/a-clinical-nutritionist-s-experience-and-expectations
#20
W P T James
No abstract text is available yet for this article.
August 2017: European Journal of Clinical Nutrition
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