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Addiction Medicine, Psychiatric Medicine

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https://www.readbyqxmd.com/read/28132694/buprenorphine-prescribing-practice-trends-and-attitudes-among-new-york-providers
#1
Andrea Kermack, Mara Flannery, Babak Tofighi, Jennifer McNeely, Joshua D Lee
Buprenorphine office-based opioid maintenance is an increasingly common form of treatment for opioid use disorders. However, total prescribing has not kept pace with the current opioid and overdose epidemic and access remains scarce among the underserved. This study sought to assess current provider attitudes and clinical practices among a targeted sample of primarily New York City public sector buprenorphine prescribers. A cross-sectional online survey purposefully sampled buprenorphine prescribers in NYC with a focus on those serving Medicaid and uninsured patient populations...
March 2017: Journal of Substance Abuse Treatment
https://www.readbyqxmd.com/read/28051841/a-review-of-a-national-training-initiative-to-increase-provider-use-of-mat-to-address-the-opioid-epidemic
#2
REVIEW
Frances R Levin, Adam Bisaga, Maria A Sullivan, Arthur Robin Williams, Kathryn Cates-Wessel
BACKGROUND AND OBJECTIVES: The Providers' Clinical Support System for Medication Assisted Treatment (PCSS-MAT) initiative focuses on training and mentoring health professionals in the treatment of opioid use disorders (OUD) using pharmacological strategies. Led by the American Academy of Addiction Psychiatry (AAAP), PCSS-MAT is a consortium representing four of the five national professional organizations authorized by DATA 2,000-AAAP, American Osteopathic Academy of Addiction Medicine, American Psychiatric Association, and American Society of Addiction Medicine...
December 2016: American Journal on Addictions
https://www.readbyqxmd.com/read/28025516/motivations-and-limitations-associated-with-vaping-among-people-with-mental-illness-a-qualitative-analysis-of-reddit-discussions
#3
Ratika Sharma, Britta Wigginton, Carla Meurk, Pauline Ford, Coral E Gartner
This study aims to understand the nature and significance of online lay discussions about e-cigarettes and mental illness. We systematically searched the website Reddit.com using keywords related to e-cigarettes and mental illness. We coded relevant posts into themes under the framework of motivations for and limitations of vaping for people with mental illness. The thematic analysis included 3263 comments from 133 discussion threads. Six themes were classified as motivations to vape for people with mental illness: Self-medication; Quitting smoking; Freedom and control; Hobby; Social connectedness; and Motivation from caregivers and online communities...
December 22, 2016: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/28019026/psychedelics-as-medicines-an-emerging-new-paradigm
#4
D E Nichols, M W Johnson, C D Nichols
Scientific interest in serotonergic psychedelics (e.g., psilocybin and LSD; 5-HT2A receptor agonists) has dramatically increased within the last decade. Clinical studies administering psychedelics with psychotherapy have shown preliminary evidence of robust efficacy in treating anxiety and depression, as well as addiction to tobacco and alcohol. Moreover, recent research has suggested that these compounds have potential efficacy against inflammatory diseases through novel mechanisms, with potential advantages over existing antiinflammatory agents...
November 4, 2016: Clinical Pharmacology and Therapeutics
https://www.readbyqxmd.com/read/28003385/evidence-for-greater-forensic-education-of-all-psychiatry-residents
#5
Howard L Forman, David W Preven
Booth and his colleagues have made an important contribution to the emerging evidence base that shows education in forensic psychiatry topics can improve attitudes toward the field. Given the desinstitutionalization of those with severe mental illness from state psychiatric facilities and the incarceration of many individuals with severe mental illness in correctional facilities, the need to train many more psychiatrists with competence in correctional settings is clear. Simply training more forensic psychiatrists will not both meet the psychiatric needs of incarcerated patients and fulfill the essential roles forensic psychiatrists play in the justice system...
December 2016: Journal of the American Academy of Psychiatry and the Law
https://www.readbyqxmd.com/read/27932945/monoaminergic-and-histaminergic-strategies-and-treatments-in-brain-diseases
#6
REVIEW
Giuseppe Di Giovanni, Dubravka Svob Strac, Montse Sole, Mercedes Unzeta, Keith F Tipton, Dorotea Mück-Šeler, Irene Bolea, Laura Della Corte, Matea Nikolac Perkovic, Nela Pivac, Ilse J Smolders, Anna Stasiak, Wieslawa A Fogel, Philippe De Deurwaerdère
The monoaminergic systems are the target of several drugs for the treatment of mood, motor and cognitive disorders as well as neurological conditions. In most cases, advances have occurred through serendipity, except for Parkinson's disease where the pathophysiology led almost immediately to the introduction of dopamine restoring agents. Extensive neuropharmacological studies first showed that the primary target of antipsychotics, antidepressants, and anxiolytic drugs were specific components of the monoaminergic systems...
2016: Frontiers in Neuroscience
https://www.readbyqxmd.com/read/27317860/lipids-in-psychiatric-disorders-and-preventive-medicine
#7
REVIEW
Miriam Schneider, Beth Levant, Martin Reichel, Erich Gulbins, Johannes Kornhuber, Christian P Müller
Psychiatric disorders like mood disorders, schizophrenia, or drug addiction affect a sizeable proportion of the human population and severely compromise quality of life. Therefore, measures to prevent the manifestation, and treatments to ameliorate the symptoms, of these disorders are in high demand. Brain lipids determine the localization and function of proteins in the cell membrane of neurons. Lipids may also act as neurotransmitters or other signalling molecules. The lipid composition of the brain can be influenced by nutrition, environmental factors, and by behavioural activity...
June 16, 2016: Neuroscience and Biobehavioral Reviews
https://www.readbyqxmd.com/read/27261367/ketamine-abuse-potential-and-use-disorder
#8
REVIEW
Yu Liu, Deyong Lin, Boliang Wu, Wenhua Zhou
Ketamine is a noncompetitive antagonist of N-methyl-d-asparate (NMDA) receptor and has been long used as an anesthetic agent in humans and veterinary medicine. The present article reviews the epidemiology, pharmacology, neurochemistry, and treatment of ketamine abuse. Ketamine has a unique mood controlling property and a number of studies have demonstrated a significant and rapid antidepressant effect of ketamine. However, the therapeutic value of ketamine to treat psychiatric disorders faces a major challenge that ketamine also owns significant reinforcing and toxic effects...
September 2016: Brain Research Bulletin
https://www.readbyqxmd.com/read/27002655/exploring-hallucinogen-pharmacology-and-psychedelic-medicine-with-zebrafish-models
#9
Evan J Kyzar, Allan V Kalueff
After decades of sociopolitical obstacles, the field of psychiatry is experiencing a revived interest in the use of hallucinogenic agents to treat brain disorders. Along with the use of ketamine for depression, recent pilot studies have highlighted the efficacy of classic serotonergic hallucinogens, such as lysergic acid diethylamide and psilocybin, in treating addiction, post-traumatic stress disorder, and anxiety. However, many basic pharmacological and toxicological questions remain unanswered with regard to these compounds...
October 2016: Zebrafish
https://www.readbyqxmd.com/read/26931193/psychiatric-disorders-are-overlooked-in-patients-with-drug-abuse
#10
Line Kruckow, Kristian Linnet, Jytte Banner
INTRODUCTION: Psychiatric disease is overlooked in drug users. Patients with both drug abuse and a psychiatric disease - dual diagnosis - suffer decreased compliance to treatment and decreased life expectancy compared with single-diagnosis patients. Identifying the patients among either drug addicts or mentally ill patients is difficult. METHODS: All drug addicts autopsied at the Department of Forensic Medicine, University of Copenhagen, Denmark, in the years 1992, 2002 and 2012 were included...
March 2016: Danish Medical Journal
https://www.readbyqxmd.com/read/26880374/guidelines-for-the-management-of-pregnant-women-with-substance-use-disorders
#11
REVIEW
Laura P McLafferty, Madeleine Becker, Nehama Dresner, Samantha Meltzer-Brody, Priya Gopalan, Jody Glance, Guitelle St Victor, Leena Mittal, Patrick Marshalek, Laura Lander, Linda L M Worley
BACKGROUND: Women of reproductive potential with substance use disorders, especially those who are pregnant, present many clinical challenges to healthcare providers, including comorbid psychiatric disorders, a history of trauma and abuse, avoidance of or poor access to prenatal care, fear of legal consequences, and countertransference reactions. METHODS: In November 2013, members of the Women's Mental Health Special Interest Group of the Academy of Psychosomatic Medicine presented a Workshop reviewing substance abuse in pregnancy, highlighting the specific contributions that psychosomatic medicine specialists can make in the care of these patients...
March 2016: Psychosomatics
https://www.readbyqxmd.com/read/26810000/molecular-mechanisms-of-cannabis-signaling-in-the-brain
#12
REVIEW
Patrick J Ronan, Narin Wongngamnit, Thomas P Beresford
Cannabis has been cultivated and used by humans for thousands of years. Research for decades was focused on understanding the mechanisms of an illegal/addictive drug. This led to the discovery of the vast endocannabinoid system. Research has now shifted to understanding fundamental biological questions related to one of the most widespread signaling systems in both the brain and the body. Our understanding of cannabinoid signaling has advanced significantly in the last two decades. In this review, we discuss the state of knowledge on mechanisms of Cannabis signaling in the brain and the modulation of key brain neurotransmitter systems involved in both brain reward/addiction and psychiatric disorders...
2016: Progress in Molecular Biology and Translational Science
https://www.readbyqxmd.com/read/26806771/reinforcement-principles-for-addiction-medicine-from-recreational-drug-use-to-psychiatric-disorder
#13
Scott Edwards
The transition from recreational drug use to addiction can be conceptualized as a pathological timeline whereby the psychological mechanisms responsible for disordered drug use evolve from positive reinforcement to favor elements of negative reinforcement. Abused substances (ranging from alcohol to psychostimulants) are initially ingested at regular occasions according to their positive reinforcing properties. Importantly, repeated exposure to rewarding substances sets off a chain of secondary reinforcing events, whereby cues and contexts associated with drug use may themselves become reinforcing and thereby contribute to the continued use and possible abuse of the substance(s) of choice...
2016: Progress in Brain Research
https://www.readbyqxmd.com/read/26688856/analysis-of-psychiatric-consultations-in-a-multidisciplinary-hospital-patients
#14
Piotr Ścisło, Karina Badura-Brzoza, Piotr Wacław Gorczyca, Michał Błachut, Robert Pudlo, Magdalena Piegza, Robert T Hese
UNLABELLED: AIM : The aim of the research is the analysis of psychiatric consultations conducted in the multi-disciplinary hospital, establishing the cause of the consultations according to ICD-10 and the analysis of psychiatric consultations regarding their number on particular wards. METHODS: Retrospective analysis of medical documentation concerning given consultations in the multidisciplinary hospital in Tarnowskie Góry in the years 2002-2010 has been conducted...
2015: Psychiatria Polska
https://www.readbyqxmd.com/read/26639682/paradoxes-of-evidence-in-russian-addiction-medicine
#15
V D Mendelevich, K Yu Zalmunin
BACKGROUND: For many years, clinical protocols for treatment of drug abuse patients and treatment standards in Russian Federation were not grounded on the principles of evidence-based medicine [1]. Recommendations for use of certain drugs were not accompanied by any indication of the level of credibility of the evidence supporting it. The appearance in 2014 of such indications in clinical recommendations can be considered a significant step forward for the science of addiction medicine [2]...
2015: International Journal of Risk & Safety in Medicine
https://www.readbyqxmd.com/read/26441394/fatal-poisoning-among-patients-with-drug-addiction
#16
MULTICENTER STUDY
Kirsten Wiese Simonsen, Dorte J Christoffersen, Jytte Banner, Kristian Linnet, Ljubica V Andersen
INTRODUCTION: Fatal poisonings among drug addicts in Denmark in 2012 were examined. Cause of death, abuse pattern and geographic differences are discussed and data are compared with previous studies. METHODS: All fatal poisonings examined at the three institutes of forensic medicine in Denmark in 2012 were included in the study. RESULTS: A total of 188 fatal intoxications were recorded. The median age increased from 37.5 in 2007 to 41.5 in 2012...
October 2015: Danish Medical Journal
https://www.readbyqxmd.com/read/26424211/opportunities-in-reform-bioethics-and-mental-health-ethics
#17
Arthur Robin Williams
Last year marks the first year of implementation for both the Patient Protection and Affordable Care Act and the Mental Health Parity and Addiction Equity Act in the United States. As a result, healthcare reform is moving in the direction of integrating care for physical and mental illness, nudging clinicians to consider medical and psychiatric comorbidity as the expectation rather than the exception. Understanding the intersections of physical and mental illness with autonomy and self-determination in a system realigning its values so fundamentally therefore becomes a top priority for clinicians...
May 2016: Bioethics
https://www.readbyqxmd.com/read/26406300/american-society-of-addiction-medicine-asam-national-practice-guideline-for-the-use-of-medications-in-the-treatment-of-addiction-involving-opioid-use
#18
Kyle Kampman, Margaret Jarvis
The Centers for Disease Control have recently described opioid use and resultant deaths as an epidemic. At this point in time, treating this disease well with medication requires skill and time that are not generally available to primary care doctors in most practice models. Suboptimal treatment has likely contributed to expansion of the epidemic and concerns for unethical practices. At the same time, access to competent treatment is profoundly restricted because few physicians are willing and able to provide it...
September 2015: Journal of Addiction Medicine
https://www.readbyqxmd.com/read/26261851/american-psychiatric-association-168th-annual-meeting-may-16-20-2015-toronto-canada
#19
A Kibble
The theme of this year's American Psychiatric Association (APA) meeting was 'Psychiatry: integrating body and mind, heart and soul', with special focus given to advances in basic and cognitive neuroscience and how these may contribute to integrated care of mental health and illness. The program featured numerous tracks and subtracks in areas of interest such as addiction psychiatry, child, adolescent and geriatric psychiatry, and psychosomatic medicine.
June 2015: Drugs of Today
https://www.readbyqxmd.com/read/25909795/-publishing-activity-of-russian-research-institutes-in-the-field-of-psychiatry-and-addictology-in-2006-2013
#20
COMPARATIVE STUDY
A V Nemtsov, S A Trushchelev, V N Krasnov
OBJECTIVE: To compare the publication activity of 6 psychiatric institutes based on the data from the Russian Citation Index (RCI). MATERIAL AND METHODS: Weighted average data of the last five years was selected for analysis: number of publications and citations per author, number of citations per publication, impact factor of journals published the papers. The analysis of the dynamics of publication activity and citations for the period of 2006-2013 for 6 institutes has been performed...
2015: Zhurnal Nevrologii i Psikhiatrii Imeni S.S. Korsakova
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