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https://www.readbyqxmd.com/read/28088666/vocal-emotion-decoding-in-the-subthalamic-nucleus-an-intracranial-erp-study-in-parkinson-s-disease
#1
Julie Péron, Olivier Renaud, Claire Haegelen, Lucas Tamarit, Valérie Milesi, Jean-François Houvenaghel, Thibaut Dondaine, Marc Vérin, Paul Sauleau, Didier Grandjean
Using intracranial local field potential (LFP) recordings in patients with Parkinson's disease (PD) undergoing deep brain stimulation (DBS), we explored the electrophysiological activity of the subthalamic nucleus (STN) in response to emotional stimuli in the auditory modality. Previous studies focused on the influence of visual stimuli. To this end, we recorded LFPs within the STN in response to angry, happy, and neutral prosodies in 13 patients with PD who had just undergone implantation of DBS electrodes...
January 12, 2017: Brain and Language
https://www.readbyqxmd.com/read/28088510/association-between-nocturnal-blood-pressure-dips-and-optic-disc-hemorrhage-in-patients-with-normal-tension-glaucoma
#2
Junki Kwon, Jinyoung Lee, Jaewan Choi, Dawoon Jeong, Michael S Kook
PURPOSE: To investigate the effect of nocturnal blood pressure (BP) dips on the occurrence of optic disc hemorrhage (ODH) in normal-tension glaucoma (NTG) patients and determine whether ODH is associated with greater likelihood of visual field progression (VFP). DESIGN: Prospective case-control study. METHODS: This study enrolled 698 eyes of 349 consecutive NTG patients who were ≥40 years old, underwent 24 hour intraocular pressure and ambulatory BP monitoring in the habitual position, were examined for ODH every 4-6 months with optic disc photography, and had ≥ five reliable VF tests with minimum follow-up of 3 years...
January 11, 2017: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/28088508/relationship-between-central-retinal-vessel-trunk-location-and-visual-field-loss-in-glaucoma
#3
Mengyu Wang, Hui Wang, Louis R Pasquale, Neda Baniasadi, Lucy Q Shen, Peter J Bex, Tobias Elze
PURPOSE: To study the relationship between horizontal central retinal vessel trunk location (CRVTL) on glaucomatous optic discs and sector-specific visual field (VF) loss. DESIGN: Retrospective, cross-sectional study. METHODS: CRVTL of 421 eyes from 421 patients was manually tracked on the horizontal optic disc axis on fundus images. Focal circumpapillary retinal nerve fiber layer thickness (cpRNFLT) measurements were extracted from optical coherence tomography (OCT)...
January 11, 2017: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/28088320/quantifying-lipid-changes-in-various-membrane-compartments-using-lipid-binding-protein-domains
#4
REVIEW
Péter Várnai, Gergő Gulyás, Dániel J Tóth, Mira Sohn, Nivedita Sengupta, Tamas Balla
One of the largest challenges in cell biology is to map the lipid composition of the membranes of various organelles and define the exact location of processes that control the synthesis and distribution of lipids between cellular compartments. The critical role of phosphoinositides, low-abundant lipids with rapid metabolism and exceptional regulatory importance in the control of almost all aspects of cellular functions created the need for tools to visualize their localizations and dynamics at the single cell level...
December 31, 2016: Cell Calcium
https://www.readbyqxmd.com/read/28088116/upconversion-color-tuning-in-ce-3-doped-liyf4-yb-3-ho-3-liyf4-nanoparticles-towards-ratiometric-fluorescence-detection-of-chromium-iii
#5
Shijiang Liu, Yangjie Li, Cheng Zhang, Liang Yang, Tingting Zhao, Ruilong Zhang, Changlong Jiang
Ratiometric fluorescence sensor exhibits advantages of sensitive response, high anti-interference ability and naked eye visualization owing to multiple independent emission peaks utilized for results analysis. To achieve such multi-emission probe, the traditional methods have involved simple mixing of two emitters or tedious synthesis processes of hybrid material. However, these probes often have problems of inconstant emission strength ratio, low light-stability, and complicated synthetic process, which limit their applications in practical field...
January 7, 2017: Journal of Colloid and Interface Science
https://www.readbyqxmd.com/read/28088066/activity-dependent-development-of-visual-receptive-fields
#6
REVIEW
Andrew Thompson, Alexandra Gribizis, Chinfei Chen, Michael C Crair
It is widely appreciated that neuronal activity contributes to the development of brain representations of the external world. In the visual system, in particular, it is well known that activity cooperates with molecular cues to establish the topographic organization of visual maps on a macroscopic scale [1,2] (Huberman et al., 2008; Cang and Feldheim, 2013), mapping axons in a retinotopic and eye-specific manner. In recent years, significant progress has been made in elucidating the role of activity in driving the finer-scale circuit refinement that shapes the receptive fields of individual cells...
January 11, 2017: Current Opinion in Neurobiology
https://www.readbyqxmd.com/read/28087445/distinct-subcomponents-of-mouse-retinal-ganglion-cell-receptive-fields-are-differentially-altered-by-light-adaptation
#7
C S Cowan, J Sabharwal, R L Seilheimer, S M Wu
The remarkable dynamic range of vision is facilitated by adaptation of retinal sensitivity to ambient lighting conditions. An important mechanism of sensitivity adaptation is control of the spatial and temporal window over which light is integrated. The retina accomplishes this by switching between parallel synaptic pathways with differing kinetics and degrees of synaptic convergence. However, the relative shifts in spatial and temporal integration are not well understood - particularly in the context of the antagonistic spatial surround...
January 10, 2017: Vision Research
https://www.readbyqxmd.com/read/28081452/differential-white-matter-involvement-associated-with-distinct-visuospatial-deficits-after-right-hemisphere-stroke
#8
Alex R Carter, Mark P McAvoy, Joshua S Siegel, Xin Hong, Serguei V Astafiev, Jennifer Rengachary, Kristi Zinn, Nicholas V Metcalf, Gordon L Shulman, Maurizio Corbetta
Visuospatial attention depends on the integration of multiple processes, and people with right hemisphere lesions after a stroke may exhibit severe or no visuospatial deficits. The anatomy of core components of visuospatial attention is an area of intense interest. Here we examine the relationship between the disruption of core components of attention and lesion distribution in a heterogeneous group (N = 70) of patients with right hemisphere strokes regardless of the presence of clinical neglect. Deficits of lateralized spatial orienting, measured as the difference in reaction times for responding to visual targets in the contralesional or ipsilesional visual field, and deficits in re-orienting attention, as measured by the difference in reaction times for invalidly versus validly cued targets, were measured using a computerized spatial orienting task...
December 20, 2016: Cortex; a Journal Devoted to the Study of the Nervous System and Behavior
https://www.readbyqxmd.com/read/28079833/the-rare-ethambutol-induced-optic-neuropathy-a-case-report-and-literature-review
#9
Wei Song, Shancheng Si
RATIONALE: Ethambutol-induced optic neuropathy (EON) is a well-known complication that results from the use of ethambutol. The ocular manifestations of EON include painless loss of central vision and cecocentral scotomas in the visual field. PATIENT CONCERNS: A 75-year-old Chinese Han man suffered from this rare ocular disorder because he took ethambutol for about 8 months. DIAGNOSES: He was diagnosed as EON based on series of ophthalmic examinations performed...
January 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28079654/retinal-oximetry-in-subjects-with-glaucomatous-hemifield-asymmetry
#10
Zhu Li Yap, Charles Ong, Yi Fang Lee, Andrew Tsai, Clarissa Cheng, Monisha E Nongpiur, Shamira A Perera
PURPOSE: Although some studies suggest a strong link between retinal vessel oxygenation and damage to the retinal nerve fiber layer (RNFL) seen in glaucoma, it has yet to be conclusively proven. This study compares intraocular retinal oximetry in glaucomatous eyes displaying asymmetrically affected hemifields across different subgroups of glaucoma, namely primary angle closure glaucoma (PACG), primary open-angle glaucoma (POAG), and normal tension glaucoma (NTG). METHODS: In this prospective cross-sectional study, 99 patients (PACG, n=28; POAG, n=37; NTG, n=34) underwent retinal oxygenation and vessel caliber measurements using the Oxymap T1 Retinal Oximeter, Cirrus optical coherence tomography, and Humphrey visual field testing...
January 10, 2017: Journal of Glaucoma
https://www.readbyqxmd.com/read/28079653/comparison-of-impact-of-monocular-and-integrated-binocular-visual-fields-on-vision-related-quality-of-life
#11
Yeoun Sook Chun, Dong Ik Lee, Jaein Kwon, In Ki Park
PURPOSE OF THE STUDY: The purpose of the study was to investigate the relationship between vision-related quality of life (VRQOL) and mean deviation (MD) of the monocular visual field and integrated binocular visual field (IBVF). METHODS: One hundred eighty VFs (90 pairs) obtained from 90 patients with normal tension glaucoma were included. VRQOL was evaluated using the 25-item National Eye Institute Visual Function Questionnaire (NEI VFQ-25). IBVF was calculated using maximal sensitivity and binocular summation and IBVF MD was calculated...
January 10, 2017: Journal of Glaucoma
https://www.readbyqxmd.com/read/28079122/environmental-dna-metabarcoding-reveals-local-fish-communities-in-a-species-rich-coastal-sea
#12
Satoshi Yamamoto, Reiji Masuda, Yukuto Sato, Tetsuya Sado, Hitoshi Araki, Michio Kondoh, Toshifumi Minamoto, Masaki Miya
Environmental DNA (eDNA) metabarcoding has emerged as a potentially powerful tool to assess aquatic community structures. However, the method has hitherto lacked field tests that evaluate its effectiveness and practical properties as a biodiversity monitoring tool. Here, we evaluated the ability of eDNA metabarcoding to reveal fish community structures in species-rich coastal waters. High-performance fish-universal primers and systematic spatial water sampling at 47 stations covering ~11 km(2) revealed the fish community structure at a species resolution...
January 12, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28078975/the-uniformity-illusion
#13
Marte Otten, Yair Pinto, Chris L E Paffen, Anil K Seth, Ryota Kanai
Vision in the fovea, the center of the visual field, is much more accurate and detailed than vision in the periphery. This is not in line with the rich phenomenology of peripheral vision. Here, we investigated a visual illusion that shows that detailed peripheral visual experience is partially based on a reconstruction of reality. Participants fixated on the center of a visual display in which central stimuli differed from peripheral stimuli. Over time, participants perceived that the peripheral stimuli changed to match the central stimuli, so that the display seemed uniform...
January 2017: Psychological Science
https://www.readbyqxmd.com/read/28077369/the-relationship-between-central-visual-field-sensitivity-and-macular-ganglion-cell-inner-plexiform-layer-thickness-in-glaucoma
#14
Ji-Woong Lee, Esteban Morales, Farideh Sharifipour, Navid Amini, Fei Yu, Abdelmonem A Afifi, Anne L Coleman, Joseph Caprioli, Kouros Nouri-Mahdavi
AIMS: To explore the correlation of local macular ganglion cell/inner plexiform layer (GC/IPL) thickness measurements with sensitivity at individual test locations on the central 10-2 visual fields (VFs) in patients with glaucoma. METHODS: One hundred thirty-seven eyes of 125 patients with spectral domain optical coherence tomography (OCT) and 10-2 VFs were included. The exported thickness matrices (200×200) of GC/IPL measurements were centred on the fovea. Total deviation values at each test location were correlated with the 20 000 GC/IPL thickness measurements in the corresponding inferior or superior hemiretina, and areas of highest correlation were plotted...
January 11, 2017: British Journal of Ophthalmology
https://www.readbyqxmd.com/read/28076567/full-field-electroretinogram-recorded-with-skin-electrodes-in-normal-adults
#15
Arthur Gustavo Fernandes, Solange Rios Salomão, Josenilson Martins Pereira, Adriana Berezovsky
Purpose: Alternative recording methods have been tested to allow the electroretinogram (ERG) recording in uncooperative patients and/or patients with palpebral alterations, including recordings with skin electrodes. The purpose of this study was to compare ERG recorded with skin electrodes and well-established microfiber electrodes and to determine normative values of ERG parameters for recording with skin electrodes. Methods: Fifty healthy volunteers (17-26 years; mean 20...
November 2016: Arquivos Brasileiros de Oftalmologia
https://www.readbyqxmd.com/read/28075330/building-an-open-source-simulation-platform-of-acoustic-radiation-force-based-breast-elastography
#16
Yu Wang, Bo Peng, Jingfeng Jiang
Ultrasound-based elastography techniques including quasi-static strain elastography (SE), acoustic radiation force Impulse (ARFI) imaging, point shear wave elastography (pSWE) and supersonic shear imaging (SSI) have been used to differentiate breast tumors. The objective of this study is to extend a previously published virtual simulation platform of SE toward acoustic radiation force-based breast elastography. The proposed platform inherited four key components from the previously published virtual SE platform: an ultrasound simulator (Field II), a mesh generator (Tetgen), a finite element (FE) solver (FEBio) and a visualization and data processing package (VTK)...
January 11, 2017: Physics in Medicine and Biology
https://www.readbyqxmd.com/read/28073365/neurophthalmological-conditions-mimicking-glaucomatous-optic-neuropathy-analysis-of-the-most-common-causes-of-misdiagnosis
#17
Diego Torres Dias, Michele Ushida, Roberto Battistella, Syril Dorairaj, Tiago Santos Prata
BACKGROUND: To analyze the most common neurophthalmological conditions that may mimic glaucomatous optic neuropathy and to determine which most often lead to misdiagnosis when evaluated by a glaucoma specialist. METHODS: We reviewed the charts of consecutive patients with optic neuropathies caused by neurophthalmological conditions screened in a single Eye Clinic within a period of 24 months. Within these enrolled patients, we selected the eyes whose fundoscopic appearance could resemble glaucoma based in pre-defined criteria (vertical cup-to-disc ratio ≥0...
January 10, 2017: BMC Ophthalmology
https://www.readbyqxmd.com/read/28073200/the-role-of-intraoperative-ultrasound-in-small-renal-mass-robotic-enucleation
#18
Roberta Gunelli, Massimo Fiori, Cristiano Salaris, Umberto Salomone, Marco Urbinati, Alexia Vici, Teo Zenico, Mauro Bertocco
INTRODUCTION: As a result of the growing evidence on tumor radical resection in literature, simple enucleation has become one of the best techniques associated to robotic surgery in the treatment of renal neoplasia, as it guarantees minimal invasiveness and the maximum sparing of renal tissue, facilitating the use of reduced or zero ischemia techniques during resection. The use of a robotic ultrasound probe represents a useful tool to detect and define tumor location, especially in poorly exophytic small renal mass...
December 30, 2016: Archivio Italiano di Urologia, Andrologia
https://www.readbyqxmd.com/read/28072878/signal-amplified-lateral-flow-test-strip-for-visual-detection-of-cu2
#19
Yulong Wang, Limin Wang, Juanjuan Xue, Jinbo Dong, Jia Cai, Xiude Hua, Minghua Wang, Cunzheng Zhang, Fengquan Liu
A signal-amplified lateral flow test strip (SA-LFTS) for the detection of Cu2+ in aqueous solution was constructed based on Cu+-catalyzed click chemistry and hybridization of single-stranded DNA (ssDNA). Alkyne and azide modified ssDNA acted as specific elements for Cu2+ recognition, and a chemical ligation product formed through Cu+-catalyzed alkyne-azide cycloaddition. Hybridization of ssDNA-labeled gold nanoparticles resulted in high sensitivity, and the output signal could be observed directly by the naked eye...
2017: PloS One
https://www.readbyqxmd.com/read/28072615/retinal-detachment-associated-with-peripapillary-staphyloma-imaged-with-swept-source-optical-coherence-tomography
#20
Daisuke Kunita, Makoto Inoue, Takashi Koto, Akito Hirakata
PURPOSE: To examine a rhegmatogenous retinal detachment (RRD) associated with a peripapillary staphyloma with swept source optical coherence tomography (SS-OCT) before and after vitrectomy and circumferential photocoagulation. METHODS: The SS-OCT images including the montage images of two patients with a RRD associated with peripapillary staphylomas were analyzed. A 34-year-old woman (Case 1) and a 70-year-old woman (Case 2) both noticed temporal visual field defects in their left eyes...
January 9, 2017: Retinal Cases & Brief Reports
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