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https://www.readbyqxmd.com/read/29045333/relationship-between-optic-nerve-head-drusen-volume-and-structural-and-functional-optic-nerve-damage
#1
Alon Skaat, Stephanie Muylaert, Rachel S Mogil, Rafael L Furlanetto, Camila F Netto, Rudrani Banik, Jeffrey M Liebmann, Robert Ritch, Sung Chul Park
PURPOSE: To assess the relationships between optic nerve head drusen (ONHD) volume, retinal nerve fiber layer (RNFL) thickness and visual field (VF) loss. METHODS: Patients with ONHD and no other ocular or systemic conditions that can affect RNFL or VF were enrolled. Serial enhanced depth imaging (EDI) optical coherence tomography (OCT) B-scans of the optic nerve head (interval between scans, ~30 μm) were obtained from each participant. ONHD volume was calculated for each eye by delineating the ONHD masses in each OCT B-scan using 3-dimensional reconstruction software...
October 17, 2017: Journal of Glaucoma
https://www.readbyqxmd.com/read/29045331/test-conditions-in-macular-visual-field-testing-in-glaucoma
#2
Mariko Eura, Chota Matsumoto, Shigeki Hashimoto, Sachiko Okuyama, Sonoko Takada, Hiroki Nomoto, Fumi Tanabe, Yoshikazu Shimomura
PURPOSE: To evaluate the suitable visual field (VF) test conditions (target size, test type, and eccentricity) for the macular region, we investigated the correlations between the ganglion cell layer (GCL) thickness and six VF test results. METHODS: We tested 32 eyes of patients (61.1±9.2 y) with preperimetric (6), early-stage (16), and moderate-stage (10) glaucoma. The VF tests included 3 SAP (the 10-2 HFA using SITA with target size III [HFA SITA (III)], full threshold with size III [HFA FULL (III)] and size I [HFA FULL (I)]) and 3 visual function-specific perimetry tests (the 10-2 SWAP, 10-2 flicker, and 10-2 Humphrey Matrix)...
October 17, 2017: Journal of Glaucoma
https://www.readbyqxmd.com/read/29045329/hybrid-deep-learning-on-single-wide-field-optical-coherence-tomography-scans-accurately-classifies-glaucoma-suspects
#3
Hassan Muhammad, Thomas J Fuchs, Nicole De Cuir, Carlos G De Moraes, Dana M Blumberg, Jeffrey M Liebmann, Robert Ritch, Donald C Hood
PURPOSE: Existing summary statistics based upon optical coherence tomographic (OCT) scans and/or visual fields (VFs) are suboptimal for distinguishing between healthy and glaucomatous eyes in the clinic. This study evaluates the extent to which a hybrid deep learning method (HDLM), combined with a single wide-field OCT protocol, can distinguish eyes previously classified as either healthy suspects or mild glaucoma. METHODS: In total, 102 eyes from 102 patients, with or suspected open-angle glaucoma, had previously been classified by 2 glaucoma experts as either glaucomatous (57 eyes) or healthy/suspects (45 eyes)...
October 17, 2017: Journal of Glaucoma
https://www.readbyqxmd.com/read/29045269/choroideremia-associated-with-a-novel-synonymous-mutation-in-gene-encoding-rep-1
#4
Jesse D Sengillo, Winston Lee, Mathieu F Bakhoum, Galaxy Y Cho, John P-W Chiang, Stephen H Tsang
PURPOSE: To report a novel synonymous mutation in CHM and the associated phenotype in an affected man and carrier mother. METHODS: Case report. RESULTS: A 34-year-old man with a long history of progressive night blindness and visual field constriction was diagnosed with choroideremia based on ocular examination and multimodal retinal imaging. Extensive chorioretinal degeneration was noted on spectral domain optical coherence tomography and fundus autofluorescence imaging...
October 17, 2017: Retinal Cases & Brief Reports
https://www.readbyqxmd.com/read/29044872/transcranial-magnetic-stimulation-of-right-inferior-parietal-cortex-causally-influences-prefrontal-activation-for-visual-detection
#5
Joana Leitão, Axel Thielscher, Hwee Ling Lee, Johannes Tuennerhoff, Uta Noppeney
For effective interactions with the environment the brain needs to form perceptual decisions based on noisy sensory evidence. Accumulating evidence suggests that perceptual decisions are formed by widespread interactions amongst sensory areas representing the noisy sensory evidence and fronto-parietal areas integrating the evidence into a decision variable that is compared to a decisional threshold. This concurrent transcranial magnetic stimulation (TMS)-fMRI study applied 10 Hz bursts of four TMS (or Sham) pulses to the intraparietal sulcus (IPS) to investigate the causal influence of IPS on the neural systems involved in perceptual decision making...
October 17, 2017: European Journal of Neuroscience
https://www.readbyqxmd.com/read/29044804/comparison-of-visual-receptive-fields-in-the-dorsolateral-prefrontal-cortex-dlpfc-and-ventral-intraparietal-area-vip-in-macaques
#6
Pooja Viswanathan, Andreas Nieder
The concept of receptive field (RF) describes the responsiveness of neurons to sensory space. Neurons in the primate association cortices have long been known to be spatially selective but a detailed characterization and direct comparison of RFs between frontal and parietal association cortices is missing. We sampled the RFs of a large number of neurons from two interconnected areas of the frontal and parietal lobes, the dorsolateral prefrontal cortex (dlPFC) and ventral intraparietal area (VIP), of rhesus monkeys by systematically presenting a moving bar during passive fixation...
October 17, 2017: European Journal of Neuroscience
https://www.readbyqxmd.com/read/29044630/fully-automatic-deformable-registration-of-pre-treatment-mri-ct-for-image-guided-prostate-radiotherapy-planning
#7
Iyas Hamdan, Julien Bert, Catherine Cheze Le Rest, Jean Pierre Tasu, Nicolas Boussion, Antoine Valeri, Guillaume Dardenne, Dimitris Visvikis
PURPOSE: In prostate radiotherapy, dose distribution may be calculated on CT images, while the MRI can be used to enhance soft tissue visualization. Therefore, a registration between MR and CT images could improve the overall treatment planning process, by improving visualization with a demonstrated inter-observer delineation variability when segmenting the prostate, which in turn can lead to a more precise planning. This registration must compensate for prostate deformations caused by changes in size and form between the acquisitions of both modalities...
October 17, 2017: Medical Physics
https://www.readbyqxmd.com/read/29044065/the-adverse-effects-of-valproic-acid-on-visual-functions-in-the-treatment-of-retinitis-pigmentosa
#8
Yüksel Totan, Emre Güler, Aslıhan Yüce, Mehmet Serdar Dervişogulları
PURPOSE: To evaluate the efficacy and safety of valproic acid (VPA) treatment in patients with retinitis pigmentosa (RP). METHODS: A total of 48 eyes of 24 patients (13 males, 11 females) with RP prescribed VPA were included. The length of VPA treatment was 6-12 months (mean 9.4 months). Parameters evaluated were best-corrected visual acuity (BCVA) (logarithm of the minimum angle of resolution [logMAR]), visual field analyses (VFAs) with Humprey automated perimetry, multifocal electroretinography (ERG) with Roland-RETI scan, and VPA side effects...
October 2017: Indian Journal of Ophthalmology
https://www.readbyqxmd.com/read/29042528/-a-case-of-ruptured-anterior-communicating-artery-aneurysm-with-visual-field-defects-and-deteriorating-to-severe-vision-loss
#9
Kazuki Sakakura, Go Ikeda, Yasunobu Nakai, Noriyuki Watanabe, Masanari Shiigai, Kazuya Uemura, Tetsuya Yamamoto, Akira Matsumura
Although Terson's syndrome is a well-known cause of vision loss due to intracerebral aneurysm rupture, optic nerve neuropathy can also occur because of other causes. Here, we report such a case, i.e., a ruptured anterior communicating artery aneurysm accompanied by vision loss and visual field disturbances due to a cause other than Terson's syndrome. A 47-year-old man presented with right superior altitudinal hemianopia. Computed tomography (CT) showed subarachnoid hemorrhage (SAH), and three-dimensional CT angiography revealed an anterior communicating artery aneurysm...
October 2017: Brain and Nerve, Shinkei Kenkyū No Shinpo
https://www.readbyqxmd.com/read/29042384/impact-of-internal-carotid-endarterectomy-on-visual-fields-a-non-randomised-prospective-cohort-study-in-austria
#10
Peter Konstantiniuk, Iris Steinbrugger, Stephan Koter, Johanna Muehlsteiner, Andreas Wedrich, Tina Cohnert
PURPOSE: The goal of this study was to determine whether internal carotid endarterectomy is associated with visual field changes. METHODS: Between March 2007 and December 2010, a cohort study involved 29 patients with stenosis of the carotid artery. All patients underwent ophthalmoscopy and kinetic visual field examination (Goldmann perimetry) preoperatively and postoperatively. Furthermore, a detailed area calculation was performed. On both the operated and the contralateral side, the areas surrounded by the different isopters (isopter areas) were determined and preoperative and postoperative values compared...
October 16, 2017: BMJ Open
https://www.readbyqxmd.com/read/29041766/image-quality-improvement-of-multi-projection-3d-display-through-tone-mapping-based-optimization
#11
Peng Wang, Xinzhu Sang, Yanhong Zhu, Songlin Xie, Duo Chen, Nan Guo, Chongxiu Yu
An optical 3D screen usually shows a certain diffuse reflectivity or diffuse transmission, and the multi-projection 3D display suffers from decreased display local contrast due to the crosstalk of multi-projection contents. A tone mapping based optimizing method is innovatively proposed to suppress the crosstalk and improve the display contrast by minimizing the visible contrast distortions between the display light field and a targeted one with enhanced contrast. The contrast distortions are weighted according to the visibility predicted by the model of human visual system, and the distortions are minimized for the given multi-projection 3D display model that enforces constrains on the solution...
August 21, 2017: Optics Express
https://www.readbyqxmd.com/read/29041543/filamentary-plasma-grating-induced-by-interference-of-two-femtosecond-laser-pulses-in-water
#12
Fengjiang Liu, Shuai Yuan, Boqu He, Junyi Nan, Mengci Jiang, Abdul Qayyum Khan, Liang'en Ding, Jiaxin Yu, Heping Zeng
We present direct observation of filamentary plasma grating induced by interference between two noncollinear infrared femtosecond pulses in water by doping with gold nanoparticles. The gold nanoparticles act as scattering media in water and visualize the fine structure of local optical fields of plasma grating. By measuring the variation of local conductivity as laser undergoes filamentation in water, the generated electron density in water is qualitatively studied. Significant enhancement of local electron density is observed at the intersecting region as two laser beams form plasma grating, indicating the breakthrough of clamped intensity of a conventional filament in water...
September 18, 2017: Optics Express
https://www.readbyqxmd.com/read/29041051/systematic-characterization-and-optimization-of-3d-light-field-displays
#13
Hekun Huang, Hong Hua
One of the key issues in conventional stereoscopic displays is the well-known vergence-accommodation conflict problem due to the lack of the ability to render correct focus cues for 3D scenes. Recently several light field display methods have been explored to reconstruct a true 3D scene by sampling either the projections of the 3D scene at different depths or the directions of the light rays apparently emitted by the 3D scene and viewed from different eye positions. These methods are potentially capable of rendering correct or nearly correct focus cues and addressing the vergence-accommodation conflict problem...
August 7, 2017: Optics Express
https://www.readbyqxmd.com/read/29040677/navigation-linked-heads-up-display-in-intracranial-surgery-early-experience
#14
Justin R Mascitelli, Leslie Schlachter, Alexander G Chartrain, Holly Oemke, Jeffrey Gilligan, Anthony B Costa, Raj K Shrivastava, Joshua B Bederson
BACKGROUND: The use of intraoperative navigation during microscope cases can be limited when attention needs to be divided between the operative field and the navigation screens. Heads-up display (HUD), also referred to as augmented reality, permits visualization of navigation information during surgery workflow. OBJECTIVE: To detail our initial experience with HUD. METHODS: We retrospectively reviewed patients who underwent HUD-assisted surgery from April 2016 through April 2017...
October 10, 2017: Operative Neurosurgery (Hagerstown, Md.)
https://www.readbyqxmd.com/read/29040292/intereye-comparison-of-ocular-factors-in-normal-tension-glaucoma-with-asymmetric-visual-field-loss-in-korean-population
#15
Eun Jung Lee, Jong Chul Han, Changwon Kee
PURPOSE: To identify ocular parameters corresponding to asymmetric visual field (VF) loss in normal tension glaucoma (NTG) through intereye comparisons. PATIENTS AND METHODS: Medical records of NTG patients with asymmetric and symmetric VF losses were retrospectively reviewed. The criterion for asymmetry in VF was 6 dB difference of mean deviation. Refractive error, intraocular pressure (IOP), central corneal thickness, ovality index, and peripapillary atrophy (PPA)/disc area ratio were obtained from each patient...
2017: PloS One
https://www.readbyqxmd.com/read/29040047/ultra-widefield-fluorescein-angiography-in-intermediate-uveitis
#16
Wipada Laovirojjanakul, Nisha Acharya, John A Gonzales
PURPOSE: To examine associations between pattern of vascular leakage on ultrawide-field fluorescein angiography (UWFFA) and visual acuity, cystoid macular edema (CME), and inflammatory activity in intermediate uveitis. METHODS: Single center cross-sectional, retrospective review of medical records, spectral domain optical coherence tomography (SD-OCT) and angiographic images of intermediate uveitis patients who underwent UWFFA over a 12-month period. RESULTS: Forty-one eyes from 24 patients were included...
October 17, 2017: Ocular Immunology and Inflammation
https://www.readbyqxmd.com/read/29039360/visualization-and-automatic-detection-of-defect-distribution-in-gan-atomic-structure-from-sampling-moir%C3%A3-phase
#17
Q H Wang, S Ri, H Tsuda, M Kodera, K Suguro, N Miyashita
Quantitative detection of defects in atomic structures is of great significance to evaluating product quality and exploring quality improvement process. In this study, a Fourier transform filtered sampling Moiré technique was proposed to visualize and detect defects in atomic arrays in a large field of view. Defect distributions, defect numbers and defect densities could be visually and quantitatively determined from a single atomic structure image at low cost. The effectiveness of the proposed technique was verified from numerical simulations...
October 17, 2017: Nanotechnology
https://www.readbyqxmd.com/read/29039259/single-camera-visual-odometry-to-track-a-surgical-x-ray-c-arm-base
#18
Hooman Esfandiari, Derek Lichti, Carolyn Anglin
This study provides a framework for a single-camera odometry system for localizing a surgical C-arm base. An application-specific monocular visual odometry system (a downward-looking consumer-grade camera rigidly attached to the C-arm base) is proposed in this research. The cumulative dead-reckoning estimation of the base is extracted based on frame-to-frame homography estimation. Optical-flow results are utilized to feed the odometry. Online positional and orientation parameters are then reported. Positional accuracy of better than 2% (of the total traveled distance) for most of the cases and 4% for all the cases studied and angular accuracy of better than 2% (of absolute cumulative changes in orientation) were achieved with this method...
October 1, 2017: Proceedings of the Institution of Mechanical Engineers. Part H, Journal of Engineering in Medicine
https://www.readbyqxmd.com/read/29038010/peripheral-visual-fields-in-abca4-stargardt-disease-and-correlation-with-disease-extent-on-ultra-widefield-fundus-autofluorescence
#19
Maria Fernanda Abalem, Benjamin Otte, Chris Andrew, Katherine A Joltikov, Kari Branham, Abigail T Fahim, Dana Schlegel, Cynthia X Qian, John R Heckenlively, Thiran Jayasundera
PURPOSE: To evaluate the disease extent on ultra-widefield fundus autofluorescence (UWF-FAF) in patients with ABCA4- Stargardt disease (STGD) and correlate this data with functional outcome measures. DESIGN: Retrospective cross sectional study SETTING: Kellogg Eye Center, University of Michigan STUDY POPULATION: Sixty-five patients with clinical diagnosis and proven pathogenic variants in the ABCA4 gene. OBSERVATIONAL PROCEDURES: The UWF-FAF images were obtained using Optos 200- degrees and classified into three types...
October 13, 2017: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/29037075/optimal-distance-of-multi-plane-sensor-in-three-dimensional-electrical-impedance-tomography
#20
Zhenhua Hao, Shihong Yue, Benyuan Sun, Huaxiang Wang
Electrical impedance tomography (EIT) is a visual imaging technique for obtaining the conductivity and permittivity distributions in the domain of interest. As an advanced technique, EIT has the potential to be a valuable tool for continuously bedside monitoring of pulmonary function. The EIT applications in any three-dimensional (3 D) field are very limited to the 3 D effects, i.e. the distribution of electric field spreads far beyond the electrode plane. The 3 D effects can result in measurement errors and image distortion...
October 16, 2017: Computer Assisted Surgery (Abingdon, England)
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