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https://www.readbyqxmd.com/read/28197211/therapeutic-effects-of-fermented-flax-seed-oil-on-nc-nga-mice-with-atopic-dermatitis-like-skin-lesions
#1
Joonhyoung Yang, Sangyeon Min, Seungug Hong
Background. Atopic Dermatitis (AD) is one of the most common chronic inflammatory skin diseases. Objective. This experiment aimed to study the effects of Fermented Flax Seed Oil (FFSO) on symptoms such as redness, eczema, and pruritus induced by AD. Materials and Methods. AD-induced NC/Nga mice were used to observe the immunological and therapeutic effects of FFSO on skin in vivo. Raw 264.7 cells were used to investigate the effects of FFSO in cells. Fc receptor expression and concentration of beta-hexosaminidase were measured...
2017: Evidence-based Complementary and Alternative Medicine: ECAM
https://www.readbyqxmd.com/read/28188068/ssr-and-morphological-trait-based-population-structure-analysis-of-130-diverse-flax-linum-usitatissimum-l-accessions
#2
Shashi Bhushan Choudhary, Hariom Kumar Sharma, Arroju Anil Kumar, Rangappa Thimmaiah Maruthi, Jiban Mitra, Isholeena Chowdhury, Binay Kumar Singh, Pran Gobinda Karmakar
A total of 130 flax accessions of diverse morphotypes and worldwide origin were assessed for genetic diversity and population structure using 11 morphological traits and microsatellite markers (15 gSSRs and 7 EST-SSRs). Analysis performed after classifying these accessions on the basis of plant height, branching pattern, seed size, Indian/foreign origin into six categories called sub-populations viz. fibre type exotic, fibre type indigenous, intermediate type exotic, intermediate type indigenous, linseed type exotic and linseed type indigenous...
February 7, 2017: Comptes Rendus Biologies
https://www.readbyqxmd.com/read/28159890/multiple-functional-self-association-interfaces-in-plant-tir-domains
#3
Xiaoxiao Zhang, Maud Bernoux, Adam R Bentham, Toby E Newman, Thomas Ve, Lachlan W Casey, Tom M Raaymakers, Jian Hu, Tristan I Croll, Karl J Schreiber, Brian J Staskawicz, Peter A Anderson, Kee Hoon Sohn, Simon J Williams, Peter N Dodds, Bostjan Kobe
The self-association of Toll/interleukin-1 receptor/resistance protein (TIR) domains has been implicated in signaling in plant and animal immunity receptors. Structure-based studies identified different TIR-domain dimerization interfaces required for signaling of the plant nucleotide-binding oligomerization domain-like receptors (NLRs) L6 from flax and disease resistance protein RPS4 from Arabidopsis Here we show that the crystal structure of the TIR domain from the Arabidopsis NLR suppressor of npr1-1, constitutive 1 (SNC1) contains both an L6-like interface involving helices αD and αE (DE interface) and an RPS4-like interface involving helices αA and αE (AE interface)...
February 3, 2017: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/28159728/protocol-for-a-24-week-randomized-controlled-study-of-once-daily-oral-dose-of-flax-lignan-to-healthy-older-adults
#4
Jane Alcorn, Susan Whiting, Navita Viveky, Yunyun Di, Kerry Mansell, Sharyle Fowler, Lilian Thorpe, Ahmed Almousa, Pui Chi Cheng, Jennifer Jones, Jennifer Billinsky, Thomas Hadjistavropoulos
BACKGROUND: Increased oxidative stress and inflammation are associated with aging, and contribute to an increased risk of chronic disease in older adults. Flaxseed lignans demonstrate antioxidant and anti-inflammatory activity, but their ability to reduce oxidative stress and inflammation markers in older adult populations has received limited investigation. OBJECTIVE: This is a chronic intervention trial of community-dwelling healthy older adults to examine the effects of a flaxseed lignan (secoisolariciresinol diglucoside; SDG) enriched supplement (BeneFlax) compared to a placebo...
February 3, 2017: JMIR Research Protocols
https://www.readbyqxmd.com/read/28158771/effect-of-whole-flax-seed-and-carbohydrase-enzymes-on-gastrointestinal-morphology-muscle-fatty-acids-and-production-performance-in-broiler-chickens
#5
K Denise Apperson, Gita Cherian
No abstract text is available yet for this article.
October 27, 2016: Poultry Science
https://www.readbyqxmd.com/read/28152982/ugt74s1-is-the-key-player-in-controlling-secoisolariciresinol-diglucoside-sdg-formation-in-flax
#6
Bourlaye Fofana, Kaushik Ghose, Jason McCallum, Frank M You, Sylvie Cloutier
BACKGROUND: Flax lignan, commonly known as secoisolariciresinol (SECO) diglucoside (SDG), has recently been reported with health-promoting activities, including its positive impact in metabolic diseases. However, not much was reported on the biosynthesis of SDG and its monoglucoside (SMG) until lately. Flax UGT74S1 was recently reported to sequentially glucosylate SECO into SMG and SDG in vitro. However, whether this gene is the only UGT achieving SECO glucosylation in flax was not known...
February 2, 2017: BMC Plant Biology
https://www.readbyqxmd.com/read/28122907/evaluating-the-effect-of-integrated-microfinance-and-health-interventions-an-updated-review-of-the-evidence
#7
Lara M J Lorenzetti, Sheila Leatherman, Valerie L Flax
BACKGROUND: Solutions delivered within firm sectoral boundaries are inadequate in achieving income security and better health for poor populations. Integrated microfinance and health interventions leverage networks of women to promote financial inclusion, build livelihoods, and safeguard against high cost illnesses. Our understanding of the effect of integrated interventions has been limited by variability in intervention, outcome, design, and methodological rigour. This systematic review synthesises the literature through 2015 to understand the effect of integrated microfinance and health programs...
January 25, 2017: Health Policy and Planning
https://www.readbyqxmd.com/read/28118137/effect-of-source-of-dna-on-the-quantitative-analysis-of-genetically-engineered-traits-using-digital-pcr-and-real-time-pcr
#8
Tigst Demeke, Jemima Malabanan, Michelle Holigroski, Monika Eng
Seven commercially available DNA extraction kits were compared with a cetyltrimethylammonium bromide (CTAB) method to determine the suitability of the extracted DNA for RainDrop digital PCR (dPCR) and real-time PCR (RT-PCR) quantification of OXY235 canola, FP967 flax, and DP305423 soybean (spiked at the 0.1% level). For the kits, the highest amount of DNA extracted from a 0.2 g sample was obtained using OmniPrep for Plant for flax and DNeasy <em>mericon</em> Food for canola and soybean. For canola, DNA extracted with the Fast ID Genomic DNA Extraction Kit, FastDNA Spin Kit, GM Quicker 2, NucleoSpin Food, and DNeasy <em>mericon</em> Food was suitable for dPCR and RT-PCR...
December 22, 2016: Journal of AOAC International
https://www.readbyqxmd.com/read/28112579/experimental-investigation-on-removal-of-suspended-particles-from-water-using-flax-fibre-geotextiles
#9
Bouamama Abbar, Abdellah Alem, Anne Pantet, Stéphane Marcotte, Nasre-Dine Ahfir, Davy Duriatti
Natural geotextiles are increasingly used in geotechnical applications such as bank protection and short-term soil reinforcement. This study aimed to highlight the behaviour of natural flax fibre geotextiles towards the retention of suspended particles present in urban runoff and often polluted. Indeed, it is well known that a large fraction of the heavy metals are often associated with the suspended particles. Long term filtration tests were performed on four laboratory filter designs. The objective was to study the influence of a nonwoven flax fibre geotextiles on suspended particles transfer through a sandy porous media under saturated conditions...
January 23, 2017: Environmental Technology
https://www.readbyqxmd.com/read/28111448/effects-of-simultaneous-supplementation-of-laying-hen-with-%C3%AE-linolenic-acid-and-eicosapentaenoic-acid-docosahexaenoic-acid-resources-on-egg-quality-and-n-3-fatty-acid-profile
#10
Pingping Zhang, Chuanqiu Tang, Hui Huang, Zongqing Ding, Yong Sun
Objective: The aim of this study was to investigate the effects of simultaneous supplementation of laying hen with a-linolenic acid (ALA) resources (flax, perilla and Eucommia ulmoides seeds) and eicosapentaenoic acid/docosahexaenoic acid (EPA/DHA) resources (Schizochytrium sp.) on egg quality and n-3 polyunsaturated fatty acids (PUFA) profile. Methods: Dietary treatments were as follows: i) diet C (control diet); ii) diet F( diet C+ 10% flaxseeds ); ⅲ) diet P, (diet C + 10% perilla seeds); ⅳ) diet E (diet C+ 10% Eucommia ulmoides seeds); ⅴ) diet A (diet C + 1...
December 27, 2016: Asian-Australasian Journal of Animal Sciences
https://www.readbyqxmd.com/read/28110324/setting-kinetics-and-mechanical-properties-of-flax-fibre-reinforced-glass-ionomer-restorative-materials
#11
Abou Neel Ensanya Ali, Young Anne M
Regardless of the excellent properties of glass ionomer cements, their poor mechanical properties limit their applications to non-load bearing areas. This study aimed to investigate the effect of incorporated short, chopped and randomly distributed flax fibers (0, 0.5, 1, 2.5, 5 and 25 wt%) on setting reaction kinetics, and mechanical and morphological properties of glass ionomer cements. Addition of flax fibers did not significantly affect the setting reaction extent. According to their content, flax fibers increased the compressive (from 148 to 250 MPa) and flexure strength (from 20 to 42 MPa)...
October 17, 2016: Journal of Biomedical Research
https://www.readbyqxmd.com/read/28105944/gene-expression-profiling-of-flax-linum-usitatissimum-l-under-edaphic-stress
#12
Alexey A Dmitriev, Anna V Kudryavtseva, George S Krasnov, Nadezhda V Koroban, Anna S Speranskaya, Anastasia A Krinitsina, Maxim S Belenikin, Anastasiya V Snezhkina, Asiya F Sadritdinova, Natalya V Kishlyan, Tatiana A Rozhmina, Olga Yu Yurkevich, Olga V Muravenko, Nadezhda L Bolsheva, Nataliya V Melnikova
BACKGROUND: Cultivated flax (Linum usitatissimum L.) is widely used for production of textile, food, chemical and pharmaceutical products. However, various stresses decrease flax production. Search for genes, which are involved in stress response, is necessary for breeding of adaptive cultivars. Imbalanced concentration of nutrient elements in soil decrease flax yields and also results in heritable changes in some flax lines. The appearance of Linum Insertion Sequence 1 (LIS-1) is the most studied modification...
November 16, 2016: BMC Plant Biology
https://www.readbyqxmd.com/read/28088102/effects-of-photoperiod-regimes-and-ultraviolet-c-radiations-on-biosynthesis-of-industrially-important-lignans-and-neolignans-in-cell-cultures-of-linum-usitatissimum-l-flax
#13
Sumaira Anjum, Bilal Haider Abbasi, Joël Doussot, Alain Favre-Réguillon, Christophe Hano
Lignans and neolignans are principal bioactive components of Linum usitatissimum L. (Flax), having multiple pharmacological activities. In present study, we are reporting an authoritative abiotic elicitation strategy of photoperiod regimes along with UV-C radiations. Cell cultures were grown in different photoperiod regimes (24h-dark, 24h-light and 16L/8D h photoperiod) either alone or in combination with various doses (1.8-10.8kJ/m(2)) of ultraviolet-C (UV-C) radiations. Secoisolariciresinol diglucoside (SDG), lariciresinol diglucoside (LDG), dehydrodiconiferyl alcohol glucoside (DCG), and guaiacylglycerol-β-coniferyl alcohol ether glucoside (GGCG) were quantified by using reverse phase-high performance liquid chromatography (RP-HPLC)...
January 7, 2017: Journal of Photochemistry and Photobiology. B, Biology
https://www.readbyqxmd.com/read/28024547/metrics-of-rhamnogalacturonan-i-with-%C3%AE-1%C3%A2-4-linked-galactan-side-chains-and-structural-basis-for-its-self-aggregation
#14
Olga N Makshakova, Tatyana A Gorshkova, Polina V Mikshina, Yuriy F Zuev, Serge Perez
Within the family of plant cell wall polysaccharides rhamnogalacturonans I are the most diverse and structurally complex members. In present study we characterize the 3-dimensional structures and dynamic features of the constituents of RG-I along MD trajectories. It is demonstrated that extended threefold helical structure of the rhamnogalacturonan linear backbone is the most energetically favorable motif. Branching helps to stabilize a conformer of the backbone twisted along 1→2 glycosidic linkage triggering the orientation of long side chains without altering the extended overall backbone chain conformation...
February 20, 2017: Carbohydrate Polymers
https://www.readbyqxmd.com/read/28008335/structure-and-function-of-the-tir-domain-from-the-grape-nlr-protein-rpv1
#15
Simon J Williams, Ling Yin, Gabriel Foley, Lachlan W Casey, Megan A Outram, Daniel J Ericsson, Jiang Lu, Mikael Boden, Ian B Dry, Bostjan Kobe
The N-terminal Toll/interleukin-1 receptor/resistance protein (TIR) domain has been shown to be both necessary and sufficient for defense signaling in the model plants flax and Arabidopsis. In examples from these organisms, TIR domain self-association is required for signaling function, albeit through distinct interfaces. Here, we investigate these properties in the TIR domain containing resistance protein RPV1 from the wild grapevine Muscadinia rotundifolia. The RPV1 TIR domain, without additional flanking sequence present, is autoactive when transiently expressed in tobacco, demonstrating that the TIR domain alone is capable of cell-death signaling...
2016: Frontiers in Plant Science
https://www.readbyqxmd.com/read/28000689/comparison-of-flax-linum-usitatissimum-and-salba-chia-salvia-hispanica-l-seeds-on-postprandial-glycemia-and-satiety-in-healthy-individuals-a-randomized-controlled-crossover-study
#16
V Vuksan, L Choleva, E Jovanovski, A L Jenkins, F Au-Yeung, A G Dias, H V T Ho, A Zurbau, L Duvnjak
BACKGROUND/OBJECTIVES: Flax and Salba-chia seeds have risen in popularity owing to their favorable nutrient composition, including a high fiber content. Despite having comparable nutritional profiles, preliminary observations suggest differences in gelling properties, an attribute that may alter the kinetics of food digestion. Thus, we compared the effect of two seeds on postprandial glycemia and satiety scores. SUBJECTS/METHODS: Fifteen healthy participants (M/F: 5/10; age: 23...
February 2017: European Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/27987846/differential-growth-of-bowel-commensal-bacteroides-species-on-plant-xylans-of-differing-structural-complexity
#17
Manuela Centanni, Jennifer C Hutchison, Susan M Carnachan, Alison M Daines, William J Kelly, Gerald W Tannock, Ian M Sims
Alterations to the composition of the bowel microbiota (dysbioses) are associated with particular diseases and conditions of humans. There is a need to discover new, indigestible polysaccharides which are selective growth substrates for commensal bowel bacteria. These substrates (prebiotics) could be added to food in intervention studies to correct bowel dysbiosis. A collection of commensal bacteria was screened for growth in culture using a highly-branched xylan produced by New Zealand flax. Two, Bacteroides ovatus ATCC 8483 and Bacteroides xylanisolvens DSM 18836 grew well on this substrate...
February 10, 2017: Carbohydrate Polymers
https://www.readbyqxmd.com/read/27981388/transcriptome-portrait-of-cellulose-enriched-flax-fibres-at-advanced-stage-of-specialization
#18
Oleg Gorshkov, Natalia Mokshina, Vladimir Gorshkov, Svetlana Chemikosova, Yuri Gogolev, Tatyana Gorshkova
Functional specialization of cells is among the most fundamental processes of higher organism ontogenesis. The major obstacle to studying this phenomenon in plants is the difficulty of isolating certain types of cells at defined stages of in planta development for in-depth analysis. A rare opportunity is given by the developed model system of flax (Linum usitatissimum L.) phloem fibres that can be purified from the surrounding tissues at the stage of the tertiary cell wall deposition. The performed comparison of the whole transcriptome profile in isolated fibres and other portions of the flax stem, together with fibre metabolism characterization, helped to elucidate the general picture of the advanced stage of plant cell specialization and to reveal novel participants potentially involved in fibre metabolism regulation and cell wall formation...
December 15, 2016: Plant Molecular Biology
https://www.readbyqxmd.com/read/27974010/outcomes-of-acute-dermal-irritation-and-sensitisation-tests-on-active-dressings-for-chronic-wounds-a-comparative-study
#19
P J Zelga, M M Górnicz, J M Głuszkiewicz, J Piasecka-Zelga
OBJECTIVE: Chronic, non-healing ulcers are a significant problem in clinical practice. The numerous complications, associated with toxicological and allergic reactions, caused by certain compounds in active dressings have been reported. The aim of this study was to evaluate the local skin tolerance of active dressings and determine which of them carries a risk of causing local skin reactions. METHOD: We tested six active dressings from different categories (hydrogel dressing, chitosan sponge dressing, silver nanoparticles dressing, dry flax fibres dressing alone and coated with linfix or oilfix) for acute irritation in rabbits and for sensitisation in guinea pigs...
December 2, 2016: Journal of Wound Care
https://www.readbyqxmd.com/read/27942165/between-china-and-south-asia-a-middle-asian-corridor-of-crop-dispersal-and-agricultural-innovation-in-the-bronze-age
#20
Chris J Stevens, Charlene Murphy, Rebecca Roberts, Leilani Lucas, Fabio Silva, Dorian Q Fuller
The period from the late third millennium BC to the start of the first millennium AD witnesses the first steps towards food globalization in which a significant number of important crops and animals, independently domesticated within China, India, Africa and West Asia, traversed Central Asia greatly increasing Eurasian agricultural diversity. This paper utilizes an archaeobotanical database (AsCAD), to explore evidence for these crop translocations along southern and northern routes of interaction between east and west...
October 2016: Holocene
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