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https://www.readbyqxmd.com/read/28088102/effects-of-photoperiod-regimes-and-ultraviolet-c-radiations-on-biosynthesis-of-industrially-important-lignans-and-neolignans-in-cell-cultures-of-linum-usitatissimum-l-flax
#1
Sumaira Anjum, Bilal Haider Abbasi, Joël Doussot, Alain Favre-Réguillon, Christophe Hano
Lignans and neolignans are principal bioactive components of Linum usitatissimum L. (Flax), having multiple pharmacological activities. In present study, we are reporting an authoritative abiotic elicitation strategy of photoperiod regimes along with UV-C radiations. Cell cultures were grown in different photoperiod regimes (24h-dark, 24h-light and 16L/8D h photoperiod) either alone or in combination with various doses (1.8-10.8kJ/m(2)) of ultraviolet-C (UV-C) radiations. Secoisolariciresinol diglucoside (SDG), lariciresinol diglucoside (LDG), dehydrodiconiferyl alcohol glucoside (DCG), and guaiacylglycerol-β-coniferyl alcohol ether glucoside (GGCG) were quantified by using reverse phase-high performance liquid chromatography (RP-HPLC)...
January 7, 2017: Journal of Photochemistry and Photobiology. B, Biology
https://www.readbyqxmd.com/read/28024547/metrics-of-rhamnogalacturonan-i-with-%C3%AE-1%C3%A2-4-linked-galactan-side-chains-and-structural-basis-for-its-self-aggregation
#2
Olga N Makshakova, Tatyana A Gorshkova, Polina V Mikshina, Yuriy F Zuev, Serge Perez
Within the family of plant cell wall polysaccharides rhamnogalacturonans I are the most diverse and structurally complex members. In present study we characterize the 3-dimensional structures and dynamic features of the constituents of RG-I along MD trajectories. It is demonstrated that extended threefold helical structure of the rhamnogalacturonan linear backbone is the most energetically favorable motif. Branching helps to stabilize a conformer of the backbone twisted along 1→2 glycosidic linkage triggering the orientation of long side chains without altering the extended overall backbone chain conformation...
February 20, 2017: Carbohydrate Polymers
https://www.readbyqxmd.com/read/28008335/structure-and-function-of-the-tir-domain-from-the-grape-nlr-protein-rpv1
#3
Simon J Williams, Ling Yin, Gabriel Foley, Lachlan W Casey, Megan A Outram, Daniel J Ericsson, Jiang Lu, Mikael Boden, Ian B Dry, Bostjan Kobe
The N-terminal Toll/interleukin-1 receptor/resistance protein (TIR) domain has been shown to be both necessary and sufficient for defense signaling in the model plants flax and Arabidopsis. In examples from these organisms, TIR domain self-association is required for signaling function, albeit through distinct interfaces. Here, we investigate these properties in the TIR domain containing resistance protein RPV1 from the wild grapevine Muscadinia rotundifolia. The RPV1 TIR domain, without additional flanking sequence present, is autoactive when transiently expressed in tobacco, demonstrating that the TIR domain alone is capable of cell-death signaling...
2016: Frontiers in Plant Science
https://www.readbyqxmd.com/read/28000689/comparison-of-flax-linum-usitatissimum-and-salba-chia-salvia-hispanica-l-seeds-on-postprandial-glycemia-and-satiety-in-healthy-individuals-a-randomized-controlled-crossover-study
#4
V Vuksan, L Choleva, E Jovanovski, A L Jenkins, F Au-Yeung, A G Dias, H V T Ho, A Zurbau, L Duvnjak
BACKGROUND/OBJECTIVES: Flax and Salba-chia seeds have risen in popularity owing to their favorable nutrient composition, including a high fiber content. Despite having comparable nutritional profiles, preliminary observations suggest differences in gelling properties, an attribute that may alter the kinetics of food digestion. Thus, we compared the effect of two seeds on postprandial glycemia and satiety scores. SUBJECTS/METHODS: Fifteen healthy participants (M/F: 5/10; age: 23...
December 21, 2016: European Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/27987846/differential-growth-of-bowel-commensal-bacteroides-species-on-plant-xylans-of-differing-structural-complexity
#5
Manuela Centanni, Jennifer C Hutchison, Susan M Carnachan, Alison M Daines, William J Kelly, Gerald W Tannock, Ian M Sims
Alterations to the composition of the bowel microbiota (dysbioses) are associated with particular diseases and conditions of humans. There is a need to discover new, indigestible polysaccharides which are selective growth substrates for commensal bowel bacteria. These substrates (prebiotics) could be added to food in intervention studies to correct bowel dysbiosis. A collection of commensal bacteria was screened for growth in culture using a highly-branched xylan produced by New Zealand flax. Two, Bacteroides ovatus ATCC 8483 and Bacteroides xylanisolvens DSM 18836 grew well on this substrate...
February 10, 2017: Carbohydrate Polymers
https://www.readbyqxmd.com/read/27981388/transcriptome-portrait-of-cellulose-enriched-flax-fibres-at-advanced-stage-of-specialization
#6
Oleg Gorshkov, Natalia Mokshina, Vladimir Gorshkov, Svetlana Chemikosova, Yuri Gogolev, Tatyana Gorshkova
Functional specialization of cells is among the most fundamental processes of higher organism ontogenesis. The major obstacle to studying this phenomenon in plants is the difficulty of isolating certain types of cells at defined stages of in planta development for in-depth analysis. A rare opportunity is given by the developed model system of flax (Linum usitatissimum L.) phloem fibres that can be purified from the surrounding tissues at the stage of the tertiary cell wall deposition. The performed comparison of the whole transcriptome profile in isolated fibres and other portions of the flax stem, together with fibre metabolism characterization, helped to elucidate the general picture of the advanced stage of plant cell specialization and to reveal novel participants potentially involved in fibre metabolism regulation and cell wall formation...
December 15, 2016: Plant Molecular Biology
https://www.readbyqxmd.com/read/27974010/outcomes-of-acute-dermal-irritation-and-sensitisation-tests-on-active-dressings-for-chronic-wounds-a-comparative-study
#7
P J Zelga, M M Górnicz, J M Głuszkiewicz, J Piasecka-Zelga
OBJECTIVE: Chronic, non-healing ulcers are a significant problem in clinical practice. The numerous complications, associated with toxicological and allergic reactions, caused by certain compounds in active dressings have been reported. The aim of this study was to evaluate the local skin tolerance of active dressings and determine which of them carries a risk of causing local skin reactions. METHOD: We tested six active dressings from different categories (hydrogel dressing, chitosan sponge dressing, silver nanoparticles dressing, dry flax fibres dressing alone and coated with linfix or oilfix) for acute irritation in rabbits and for sensitisation in guinea pigs...
December 2, 2016: Journal of Wound Care
https://www.readbyqxmd.com/read/27942165/between-china-and-south-asia-a-middle-asian-corridor-of-crop-dispersal-and-agricultural-innovation-in-the-bronze-age
#8
Chris J Stevens, Charlene Murphy, Rebecca Roberts, Leilani Lucas, Fabio Silva, Dorian Q Fuller
The period from the late third millennium BC to the start of the first millennium AD witnesses the first steps towards food globalization in which a significant number of important crops and animals, independently domesticated within China, India, Africa and West Asia, traversed Central Asia greatly increasing Eurasian agricultural diversity. This paper utilizes an archaeobotanical database (AsCAD), to explore evidence for these crop translocations along southern and northern routes of interaction between east and west...
October 2016: Holocene
https://www.readbyqxmd.com/read/27933082/rna-seq-transcriptome-response-of-flax-linum-usitatissimum-l-to-the-pathogenic-fungus-fusarium-oxysporum-f-sp-lini
#9
Leonardo Galindo-González, Michael K Deyholos
Fusarium oxysporum f. sp. lini is a hemibiotrophic fungus that causes wilt in flax. Along with rust, fusarium wilt has become an important factor in flax production worldwide. Resistant flax cultivars have been used to manage the disease, but the resistance varies, depending on the interactions between specific cultivars and isolates of the pathogen. This interaction has a strong molecular basis, but no genomic information is available on how the plant responds to attempted infection, to inform breeding programs on potential candidate genes to evaluate or improve resistance across cultivars...
2016: Frontiers in Plant Science
https://www.readbyqxmd.com/read/27927184/ty1-copia-elements-reveal-diverse-insertion-sites-linked-to-polymorphisms-among-flax-linum-usitatissimum-l-accessions
#10
Leonardo Galindo-González, Corinne Mhiri, Marie-Angèle Grandbastien, Michael K Deyholos
BACKGROUND: Initial characterization of the flax genome showed that Ty1-copia retrotransposons are abundant, with several members being recently inserted, and in close association with genes. Recent insertions indicate a potential for ongoing transpositional activity that can create genomic diversity among accessions, cultivars or varieties. The polymorphisms generated constitute a good source of molecular markers that may be associated with phenotype if the insertions alter gene activity...
December 7, 2016: BMC Genomics
https://www.readbyqxmd.com/read/27909031/a-topical-gel-from-flax-seed-oil-compared-with-hand-splint-in-carpal-tunnel-syndrome-a-randomized-clinical-trial
#11
Mohammad Setayesh, Amir Reza Sadeghifar, Nozar Nakhaee, Mohammad Kamalinejad, Hossein Rezaeizadeh
This study compared the therapeutic effect of flax seed oil topical gel and hand splint in the treatment of carpal tunnel syndrome. This study was a randomized clinical trial. Forty-nine patients, 96 hands, with mild to moderate idiopathic carpal tunnel syndrome were divided into 2 groups randomly. One group was treated by topical gel and the other group by hand splint. Intensity of symptoms and function before and after intervention was measured via Boston Carpal Tunnel Questionnaire. After intervention, the ANCOVA showed a significant difference between the symptom and function scores of the 2 groups...
December 1, 2016: Journal of Evidence-based Complementary & Alternative Medicine
https://www.readbyqxmd.com/read/27894899/dietary-flax-seed-oil-and-or-vitamin-e-improve-sperm-parameters-of-cloned-goats-following-freezing-thawing
#12
Rohollah Kargar, Mohsen Forouzanfar, Gholamreza Ghalamkari, Mohammad Hossein Nasr Esfahani
Semen cryopreservation is affected by individual differences and use of clones animal from the same source is the main tool to eliminate genetic variation. Among many nutrients that are necessary for fertility, essential fatty acids and antioxidants are vital for production of healthy sperm by improving sperm membrane integrity and protecting sperm from oxidative stress. The goal of the current study was to investigate whether a flax seed oil or/and Vitamin E dietary supplementation could improve semen quality of cloned bucks following semen cryopreservation...
November 25, 2016: Cryobiology
https://www.readbyqxmd.com/read/27826669/behavioral-and-molecular-genetics-of-reading-related-am-and-fm-detection-thresholds
#13
Matthew Bruni, Judy F Flax, Steven Buyske, Amber D Shindhelm, Caroline Witton, Linda M Brzustowicz, Christopher W Bartlett
Auditory detection thresholds for certain frequencies of both amplitude modulated (AM) and frequency modulated (FM) dynamic auditory stimuli are associated with reading in typically developing and dyslexic readers. We present the first behavioral and molecular genetic characterization of these two auditory traits. Two extant extended family datasets were given reading tasks and psychoacoustic tasks to determine FM 2 Hz and AM 20 Hz sensitivity thresholds. Univariate heritabilities were significant for both AM (h (2)  = 0...
November 9, 2016: Behavior Genetics
https://www.readbyqxmd.com/read/27807734/lipid-lowering-with-soluble-dietary-fiber
#14
REVIEW
Prasanth Surampudi, Byambaa Enkhmaa, Erdembileg Anuurad, Lars Berglund
Consumption of dietary soluble fibers has been associated with health benefits such as reduced lipid levels, lower blood pressure, improved blood glucose control, weight loss, improved immune function, and reduced inflammation. Many of these health benefits relate to a reduced risk of developing cardiovascular disease. In this paper, we have reviewed recent studies on the hypocholesterolemic effects of dietary soluble fibers as well as fiber-rich foods. Findings include the following: (a) consumption of water-soluble, viscous-forming fibers can reduce total and low-density lipoprotein cholesterol levels by about 5-10 %; (b) minimal changes of high-density lipoprotein cholesterol or triglyceride levels were observed; (c) cholesterol-lowering properties of soluble fibers depend on their physical and chemical properties; and (d) medium to high molecular weight fibers are more effective in reducing lipid levels...
December 2016: Current Atherosclerosis Reports
https://www.readbyqxmd.com/read/27804268/effects-of-canola-and-high-oleic-acid-canola-oils-on-abdominal-fat-mass-in-individuals-with-central-obesity
#15
Xiaoran Liu, Penny M Kris-Etherton, Sheila G West, Benoît Lamarche, David J A Jenkins, Jennifer A Fleming, Cindy E McCrea, Shuaihua Pu, Patrick Couture, Philip W Connelly, Peter J H Jones
OBJECTIVE: To determine the effect of diets low in saturated fatty acids and high in monounsaturated fatty acids (MUFA) or polyunsaturated fatty acids on body composition in participants at risk for metabolic syndrome (MetS). METHODS: This study was a randomized, crossover, controlled feeding study. Participants (n = 101, ages 49.5 ± 1.2, BMI 29.4 ± 0.4 kg/m(2) ) were randomized to five isocaloric diets containing treatment oils: Canola, CanolaOleic, CanolaDHA, Corn/Safflower, and Flax/Safflower...
November 2016: Obesity
https://www.readbyqxmd.com/read/27777570/interactions-between-obesity-status-and-dietary-intake-of-monounsaturated-and-polyunsaturated-oils-on-human-gut-microbiome-profiles-in-the-canola-oil-multicenter-intervention-trial-comit
#16
Shuaihua Pu, Hamidreza Khazanehei, Peter J Jones, Ehsan Khafipour
Long-term dietary fatty acid intake is believed to induce changes in the human gut microbiome which might be associated with human health or obesity status; however, considerable debate remains regarding the most favorable ratios of fatty acids to optimize these processes. The objective of this sub-study of a double-blinded randomized crossover clinical study, the canola oil multi-center intervention trial, was to investigate effects of five different novel oil blends fed for 30 days each on the intestinal microbiota in 25 volunteers with risk of metabolic syndrome...
2016: Frontiers in Microbiology
https://www.readbyqxmd.com/read/27776375/investigation-of-the-lignan-content-in-extracts-from-linum-callitris-and-juniperus-species-in-relation-to-their-in-vitro-antiproliferative-activities
#17
Joël Doussot, Véronique Mathieu, Cyril Colas, Roland Molinié, Cyrielle Corbin, Josiane Montguillon, Laeticia Moreno Y Banuls, Sullivan Renouard, Frédéric Lamblin, Patricia Dupré, Benoit Maunit, Robert Kiss, Christophe Hano, Eric Lainé
Podophyllotoxin, a lignan still extracted from the rhizomes of Podophyllum hexandrum (Berberidaceae), is the starting molecule for the semisynthesis of widely used anticancer drugs such as etoposide. However, this source is threatened by the over-collection of P. hexandrum. Plants belonging to the Linaceae and Cupressaceae families could be attractive alternative sources with species that contain the lignan podophyllotoxin or its precursors and derivatives. Wild flax species, such as Linum flavum, as well as some Juniperus and Callitris species were investigated for their lignan content, and the in vitro antiproliferative capacity of their extracts was assayed on four tumor cell lines...
October 24, 2016: Planta Medica
https://www.readbyqxmd.com/read/27765874/effect-of-whole-flax-seed-and-carbohydrase-enzymes-on-gastrointestinal-morphology-muscle-fatty-acids-and-production-performance-in-broiler-chickens
#18
K Denise Apperson, Gita Cherian
Flax seed is a rich source of α-linolenic acid (18:3 n-3). Feeding broiler birds flax seed can increase n-3 fatty acids in meat tissues. However, non-starch polysaccharides in flax seed decrease nutrient digestibility and can have a negative impact on bird performance and muscle fatty acid content. Addition of carbohydrase enzymes to flax-based broiler diets can decrease the anti-nutritive effects of non-starch polysaccharides. An experiment was conducted to investigate on the effect of flax seed and carbohydrase enzyme foregut morphology, muscle tissue, fatty acids, and bird performance...
October 19, 2016: Poultry Science
https://www.readbyqxmd.com/read/27754430/reflux-incidence-among-exclusively-breast-milk-fed-infants-differences-of-feeding-at-breast-versus-pumped-milk
#19
Jennifer Yourkavitch, Sabrina Zadrozny, Valerie L Flax
The practice of feeding infants expressed breast milk is increasing in the United States, but the impacts on infant and maternal health are still understudied. This study examines the monthly incidence of regurgitation (gastro-esophageal reflux) in exclusively breast milk fed infants from ages two to six months. Among infants whose mothers participated in the Infant Feeding Practices II Study (IFPS II; 2005-2007), data on reflux and feeding mode were collected by monthly questionnaires. A longitudinal, repeated measures analysis was used, with feeding mode lagged by one month in order to compare reflux incidence among infants fed directly at the breast to infants receiving pumped breast milk...
October 14, 2016: Children
https://www.readbyqxmd.com/read/27669375/designing-a-clean-label-sponge-cake-with-reduced-fat-content
#20
Cristina Eslava-Zomeño, Amparo Quiles, Isabel Hernando
The fat in a sponge cake formulation was partially replaced (0%, 30%, 50%, and 70%) with OptiSol™5300.This natural functional ingredient derived from flax seeds, rich in fiber and alpha-linoleic acid, provides a natural substitute for guar and xanthan gums, avoiding E-numbers on labels. The structure and some physicochemical properties of the formulations were examined, sensory analysis was conducted and changes in starch digestibility due to adding this ingredient were determined. Increasing quantities of OptiSol™5300 gave harder cakes, with less weight loss during baking, without affecting the final cake height...
October 2016: Journal of Food Science
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