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https://www.readbyqxmd.com/read/29465252/increasing-uptake-of-comparative-effectiveness-and-patient-centered-outcomes-research-among-stakeholders-insights-from-conference-discussion
#1
Ernest Law, Rachel Harrington, G Caleb Alexander, Soumi Saha, Elisabeth Oehrlein, Eleanor M Perfetto
The goal of comparative effectiveness research (CER) and patient-centered outcomes research (PCOR) is to improve health outcomes by providing stakeholders with evidence directly relevant to decision making. In January 2017, the Pharmaceutical Research and Manufacturers Association Foundation, alongside the Academy for Managed Care Pharmacy, organized a conference aimed at engaging experts and opinion leaders representing clinicians, patients and payers to identify and discuss barriers and strategies to enhancing uptake and use of CER/PCOR...
February 21, 2018: Journal of Comparative Effectiveness Research
https://www.readbyqxmd.com/read/29464435/palliative-care-for-movement-disorders
#2
REVIEW
Christina L Vaughan, Benzi M Kluger
PURPOSE OF REVIEW: While care for patients with movement disorders has traditionally focused on motor symptoms, there is increasing evidence that optimal care for these disorders is more complex both in terms of the spectrum of symptoms experienced by patients (e.g., pain, depression) and the multidimensional needs of patients and their families. Palliative care is an approach to the care of patients and families affected by serious illnesses that seeks to relieve suffering by addressing complex medical symptoms, psychosocial issues, spiritual well-being, and goals of care...
February 21, 2018: Current Treatment Options in Neurology
https://www.readbyqxmd.com/read/29451026/the-tim-system-developing-a-novel-telehealth-service-to-improve-access-to-specialist-care-in-motor-neurone-disease-using-user-centered-design
#3
Esther V Hobson, Wendy O Baird, Rebecca Partridge, Cindy L Cooper, Susan Mawson, Ann Quinn, Pamela J Shaw, Theresa Walsh, Daniel Wolstenholme, Christopher J Mcdermott
OBJECTIVES: Attendance at a specialist multidisciplinary motor neurone disease (MND) clinic is associated with improved survival and may also improve quality of life and reduce hospital admissions. However, patients struggle to travel to clinic and may experience difficulties between clinic visits that may not be addressed in a timely manner. We wanted to explore how we could improve access to specialist MND care. METHODS: We adopted an iterative, user-centered co-design approach, collaborating with those with experience of providing and receiving MND care including patients, carers, clinicians, and technology developers...
February 16, 2018: Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration
https://www.readbyqxmd.com/read/29447742/a-comparative-analysis-of-current-lipid-treatment-guidelines-nothing-stands-still
#4
REVIEW
Anjan Tibrewala, Arif Jivan, William J Oetgen, Neil J Stone
Lipid treatment guidelines have continued to evolve as new evidence emerges. We sought to review similarities and differences of 5 lipid treatment guidelines from the American College of Cardiology/American Heart Association, Canadian Cardiovascular Society, European Society for Cardiology/European Atherosclerosis Society, U.S. Preventive Services Task Force, and U.S. Veterans Affairs/Department of Defense. All guidelines utilize rigorous evidentiary review, highlight statin therapy for primary and secondary prevention of atherosclerotic cardiovascular disease, and emphasize a clinician-patient risk discussion...
February 20, 2018: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/29441511/-cardiology-telemedicine-solutions-opinion-of-the-committee-of-informatics-and-telemedicine-of-polish-society-of-cardiology-section-of-non-invasive-electrocardiology-and-telemedicine-of-polish-society-of-cardiology-and-clinical-sciences-committee-of-the
#5
Ryszard Piotrowicz, Paweł Krzesiński, Paweł Balsam, Maciej Kempa, Renata Główczyńska, Marcin Grabowski, Łukasz Kołtowski, Ewa Lewicka, Michał Peller, Ewa Piotrowicz, Jakub Podolec, Adam Stańczyk, Justyna Zajdel, Grzegorz Opolski
For several years, we have observed the dynamic development of technologies that allow patients to access medical care from the comfort of their homes, without direct contact with the doctor. Innovative solutions based on telemedicine improve care coordination and communication among clinicians, patients, and their families, as well as increases patients' security and gives them greater independence, thus eliminating health care inequalities. The rapidly growth of telemedicine and the adoption of new technologies in clinical practice is also observed in Poland...
February 14, 2018: Kardiologia Polska
https://www.readbyqxmd.com/read/29440161/clinician-patient-and-general-public-beliefs-about-diagnostic-imaging-for-low-back-pain-protocol-for-a-qualitative-evidence-synthesis
#6
Adrian C Traeger, Benjamin J Reed, Denise A O'Connor, Tammy C Hoffmann, Gustavo C Machado, Carissa Bonner, Chris G Maher, Rachelle Buchbinder
INTRODUCTION: Little is known about how to reduce unnecessary imaging for low back pain. Understanding clinician, patient and general public beliefs about imaging is critical to developing strategies to reduce overuse. OBJECTIVE: To synthesise qualitative research that has explored clinician, patient or general public beliefs about diagnostic imaging for low back pain. METHODS AND ANALYSIS: We will perform a qualitative evidence synthesis of relevant qualitative research exploring clinician, patient and general public beliefs about diagnostic imaging for low back pain...
February 10, 2018: BMJ Open
https://www.readbyqxmd.com/read/29422231/health-professional-patient-communication-practices-in-east-asia-an-integrative-review-of-an-emerging-field-of-research-and-practice-in-hong-kong-south-korea-japan-taiwan-and-mainland-china
#7
REVIEW
Jack K H Pun, E Angela Chan, Sophie Wang, Diana Slade
OBJECTIVE: To provide an integrative review of literature on health communication in East Asia and detail culturally-specific influences. METHODS: Using PRISMA model, search of PubMed, PsychInfo, Web of Knowledge, ERIC and CINAHL databases were conducted for studies between January 2000 and March 2017, using the terms 'clinician/health professional-patient', 'nurse/doctor-patient, 'communication' and 'Asia'. RESULTS: 38 studies were included: Mainland China, Hong Kong, Japan, South Korea, and Taiwan...
January 31, 2018: Patient Education and Counseling
https://www.readbyqxmd.com/read/29393136/acute-kidney-injury-and-information-technology
#8
Mira Küllmar, Alexander Zarbock
Acute kidney injury (AKI) is a common complication that occurs in critically ill patients and it is associated with a worse outcome. Since therapy options are limited, prevention and early detection are the essential cornerstones to improve patient outcomes. Therefore, using health information technology (HIT) to detect AKI early might be useful for clinicians. Patient data can be extracted real-time from electronic health records. Programmed electronic alert systems (e-alerts) can increase clinicians' awareness for AKI...
2018: Contributions to Nephrology
https://www.readbyqxmd.com/read/29384901/acupuncture-for-idiopathic-pulmonary-fibrosis-protocol-for-a-systematic-review
#9
Yang Xie, Jia-Jia Wang, Gao-Yang Li, Xuan-Lin Li, Jian-Sheng Li
BACKGROUND: Patients with idiopathic pulmonary fibrosis (IPF) often suffer from progressive worsening of dyspnea and lung function. Although 2 drugs are now available for IPF treatment, many gaps are still to be filled. Evidences suggest that there may be some beneficial effect of acupuncture on pulmonary diseases. This review aims to systematically determine the efficacy and safety of acupuncture for treating IPF. METHODS: The following 8 databases will be searched from their inception to March 20, 2017: PubMed, Embase, Cochrane Central Register of Controlled Trials, Web of Science, Chinese Biomedical Literature Database, China National Knowledge Infrastructure, Chongqing VIP, and Wanfang Data...
December 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29378425/developing-a-tool-to-support-diagnostic-delivery-of-dementia
#10
Claire E Bennett, Danielle De Boos, Nima G Moghaddam
It is increasingly recognised that there are challenges affecting the current delivery of dementia diagnoses. Steps are required to address this. Current good practice guidelines provide insufficient direction and interventions from other healthcare settings do not appear to fully translate to dementia care settings. This project has taken a sequential two-phase design to developing a tool specific to dementia diagnostic delivery. Interviews with 14 participants explored good diagnostic delivery. Thematic analysis produced key themes (overcoming barriers, navigation of multiple journeys and completing overt and covert tasks) that were used to inform the design of a tool for use by clinicians, patients and companions...
January 1, 2018: Dementia
https://www.readbyqxmd.com/read/29375067/mediative-fluency-and-futility-disputes
#11
Samantha F Knowlton, Joseph J Fins
Futility disputes are more likely to be resolved-and relational breaches repaired-by engaging in a process that fosters communication between clinicians, patients, and families. This essay calls for mediative fluency. The preemptive use of a futility definition can stifle conversation when it is needed most, exacerbating the very power imbalances and associated health disparities that often precipitate futility disputes. When clinicians, patients, and families engage in dialogue, clinicians can appreciate what motivates requests for what is thought to be futile care, and patients and families can better understand the limits of available therapies...
2018: Perspectives in Biology and Medicine
https://www.readbyqxmd.com/read/29358433/randomised-controlled-trial-to-determine-the-efficacy-and-safety-of-prescribed-water-intake-to-prevent-kidney-failure-due-to-autosomal-dominant-polycystic-kidney-disease-prevent-adpkd
#12
Annette T Y Wong, Carly Mannix, Jared J Grantham, Margaret Allman-Farinelli, Sunil V Badve, Neil Boudville, Karen Byth, Jessie Chan, Susan Coulshed, Marie E Edwards, Bradley J Erickson, Mangalee Fernando, Sheryl Foster, Imad Haloob, David C H Harris, Carmel M Hawley, Julie Hill, Kirsten Howard, Martin Howell, Simon H Jiang, David W Johnson, Timothy L Kline, Karthik Kumar, Vincent W Lee, Maureen Lonergan, Jun Mai, Philip McCloud, Anthony Peduto, Anna Rangan, Simon D Roger, Kamal Sud, Vincent Torres, Eswari Vliayuri, Gopala K Rangan
INTRODUCTION: Maintaining fluid intake sufficient to reduce arginine vasopressin (AVP) secretion has been hypothesised to slow kidney cyst growth in autosomal dominant polycystic kidney disease (ADPKD). However, evidence to support this as a clinical practice recommendation is of poor quality. The aim of the present study is to determine the long-term efficacy and safety of prescribed water intake to prevent the progression of height-adjusted total kidney volume (ht-TKV) in patients with chronic kidney disease (stages 1-3) due to ADPKD...
January 21, 2018: BMJ Open
https://www.readbyqxmd.com/read/29342367/cystic-fibrosis-pulmonary-guidelines-use-of-cftr-modulator-therapy-in-patients-with-cystic-fibrosis
#13
Clement L Ren, Rebecca L Morgan, Christopher Oermann, Helaine E Resnick, Cynthia Brady, Annette Campbell, Richard DeNagel, Margaret Guill, Jeffrey Hoag, Andrew Lipton, Thomas Newton, Stacy Peters, Donna Beth Willey-Courand, Edward T Naureckas
BACKGROUND: CFTR modulators are a new class of medications that target the underlying defect in in cystic fibrosis (CF). Ivacaftor (IVA) and IVA combined with lumacaftor (IVA/LUM) have been approved by the FDA for use in CF patients. However, the FDA label for these medications encompasses patient groups that were not studied as part of the drug approval process. CF clinicians, patients, and their families have recognized a need for recommendations to guide the use of these medications...
January 17, 2018: Annals of the American Thoracic Society
https://www.readbyqxmd.com/read/29331842/predicting-1-year-disability-and-mortality-of-injured-older-adults
#14
Alvin D Jeffery, Mary S Dietrich, Cathy A Maxwell
PURPOSE: The growing incidence of elderly patients injured from falls, combined with a growing understanding of the contribution of cognition and frailty to mortality, prompted this work. Our objective was to develop a clinical risk prediction model for prognosticating disability and mortality among injured older adults 1 year after hospitalization. METHODS: Secondary analysis of prospective longitudinal data from an urban Level 1 trauma center. A proportional odds regression model was used to model mortality and functional status as ordinal outcomes...
January 6, 2018: Archives of Gerontology and Geriatrics
https://www.readbyqxmd.com/read/29326191/establishing-anchor-based-minimally-important-differences-mid-with-the-eortc-quality-of-life-measures-a-meta-analysis-protocol
#15
Zebedee Jammbe Musoro, Jean-Francois Hamel, Divine Ewane Ediebah, Kim Cocks, Madeleine T King, Mogens Groenvold, Mirjam A G Sprangers, Yvonne Brandberg, Galina Velikova, John Maringwa, Hans-Henning Flechtner, Andrew Bottomley, Corneel Coens
INTRODUCTION: As patient assessment of health-related quality of life (HRQOL) in cancer clinical trials has increased over the years, so has the need to attach meaningful interpretations to differences in HRQOL scores between groups and changes within groups. Determining what represents a minimally important difference (MID) in HRQOL scores is useful to clinicians, patients and researchers, and can be used as a benchmark for assessing the success of a healthcare intervention. Our objective is to provide an evidence-based protocol to determine MIDs for the European Organisation for Research and Treatment for Cancer Quality of life Questionnaire core 30 (EORTC QLQ-C30)...
January 10, 2018: BMJ Open
https://www.readbyqxmd.com/read/29299646/deaths-in-incorrectly-identified-low-surgical-risk-patients
#16
C R Jones, G A J McCulloch, G Ludbrook, W J Babidge, G J Maddern
BACKGROUND: The American Society of Anesthesiologists (ASA) physical classification system was developed for assessing anaesthetic risk, but is often also used to estimate surgical death risk. Patients with low ASA grades (ASA 1 or 2) are expected to have better surgical outcomes than patients with higher ASA grades (ASA ≥ 4). This study examined the course to death in patients classified as ASA 1 or 2 was examined, to investigate possible factors in unexpected deaths, in addition to evaluating the use of ASA grades by clinicians...
January 3, 2018: World Journal of Surgery
https://www.readbyqxmd.com/read/29295027/intimate-partner-violence-among-patients-with-dissociative-disorders
#17
Aliya R Webermann, Bethany L Brand, Shaina A Kumar
Childhood trauma is common among survivors and perpetrators of intimate partner violence (IPV). Although symptoms of posttraumatic stress disorder (PTSD) and dissociative disorders (DDs) are predictors of IPV victimization and perpetration, few studies explore IPV among those with DDs. The present study examined IPV and symptoms as predictors among participants in the Treatment of Patients With Dissociative Disorders (TOP DD) Network study, an educational intervention for individuals with DDs and their clinicians...
December 1, 2017: Journal of Interpersonal Violence
https://www.readbyqxmd.com/read/29241357/cannabidiol-cbd-as-an-adjunctive-therapy-in-schizophrenia-a-multicenter-randomized-controlled-trial
#18
Philip McGuire, Philip Robson, Wieslaw Jerzy Cubala, Daniel Vasile, Paul Dugald Morrison, Rachel Barron, Adam Taylor, Stephen Wright
OBJECTIVE: Research in both animals and humans indicates that cannabidiol (CBD) has antipsychotic properties. The authors assessed the safety and effectiveness of CBD in patients with schizophrenia. METHOD: In an exploratory double-blind parallel-group trial, patients with schizophrenia were randomized in a 1:1 ratio to receive CBD (1000 mg/day; N=43) or placebo (N=45) alongside their existing antipsychotic medication. Participants were assessed before and after treatment using the Positive and Negative Syndrome Scale (PANSS), the Brief Assessment of Cognition in Schizophrenia (BACS), the Global Assessment of Functioning scale (GAF), and the improvement and severity scales of the Clinical Global Impressions Scale (CGI-I and CGI-S)...
December 15, 2017: American Journal of Psychiatry
https://www.readbyqxmd.com/read/29237477/the-impact-of-glaucoma-on-quality-of-life-in-ethiopia-a-case-control-study
#19
Fisseha A Ayele, Banchamelak Zeraye, Yared Assefa, Kbrom Legesse, Telake Azale, Matthew J Burton
BACKGROUND: Glaucoma is a chronic disease characterized by irreversible optic nerve damage and visual field loss that leads to visual impairment and blindness; ultimately limiting personal independence and compromising overall quality of life of affected individuals. There is paucity of information on how glaucoma affects the quality of life of patients in low and middle-income countries where resources for both diagnosis and treatment of such conditions are limited. In this study we investigate the impact of glaucoma on quality of life in Ethiopian patients...
December 13, 2017: BMC Ophthalmology
https://www.readbyqxmd.com/read/29228200/ect-has-greater-efficacy-than-fluoxetine-in-alleviating-the-burden-of-illness-for-patients-with-major-depressive-disorder-a-taiwanese-pooled-analysis
#20
Ching-Hua Lin, Chun-Jen Huang, Cheng-Chung Chen
Background: The burden of major depressive disorder (MDD) includes suffering due to symptom severity, functional impairment, and quality of life (QOL) deficits. The aim of this study was to compare the differences between ECT and pharmacotherapy in reducing such burdens. Methods: This was a pooled analysis study including two open-label trials for MDD inpatients receiving either standard bitemporal and modified ECT with a maximum of 12 sessions, or 20 mg/d of fluoxetine for 6 weeks...
December 8, 2017: International Journal of Neuropsychopharmacology
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