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https://www.readbyqxmd.com/read/29778859/diagnosis-of-nonischemic-stage-b-heart-failure-in-type-2-diabetes-mellitus-optimal-parameters-for-prediction-of-heart-failure
#1
Ying Wang, Hong Yang, Quan Huynh, Mark Nolan, Kazuaki Negishi, Thomas H Marwick
OBJECTIVES: This study sought to identify whether impaired global longitudinal strain (GLS), diastolic dysfunction (DD), or left atrial enlargement (LAE) should be added to stage B heart failure (SBHF) criteria in asymptomatic patients with type 2 diabetes mellitus. BACKGROUND: SBHF is a precursor to clinical heart failure (HF), and its recognition justifies initiation of cardioprotective therapy. However, original definitions of SBHF were based on LV hypertrophy and impaired ejection fraction...
May 11, 2018: JACC. Cardiovascular Imaging
https://www.readbyqxmd.com/read/29777140/different-responses-of-left-atrium-and-left-atrial-appendage-to-radiofrequency-catheter-ablation-of-atrial-fibrillation-a-follow-up-mri-study
#2
Yun Gi Kim, Jaemin Shim, Suk-Kyu Oh, Hee-Soon Park, Kwang-No Lee, Sung Ho Hwang, Jong-Il Choi, Young-Hoon Kim
Atrial fibrillation (AF) is known to cause adverse remodeling of left atrium (LA). Radiofrequency catheter ablation (RFCA) of AF is associated with decrease in LA volume. However, the impact of RFCA on left atrial appendage (LAA) volume and hemodynamic function is not fully understood. We analyzed 123 patients who underwent cardiac magnetic resonance imaging (MRI) evaluation before and after RFCA in Korea University Anam Hospital. LA and LAA volume were measured before and after RFCA based on cardiac MRI. Baseline LA volume was 99...
May 18, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29770201/recent-advances-in-managing-septal-defects-ventricular-septal-defects-and-atrioventricular-septal-defects
#3
REVIEW
P Syamasundar Rao, Andrea D Harris
This review discusses the management of ventricular septal defects (VSDs) and atrioventricular septal defects (AVSDs). There are several types of VSDs: perimembranous, supracristal, atrioventricular septal, and muscular. The indications for closure are moderate to large VSDs with enlarged left atrium and left ventricle or elevated pulmonary artery pressure (or both) and a pulmonary-to-systemic flow ratio greater than 2:1. Surgical closure is recommended for large perimembranous VSDs, supracristal VSDs, and VSDs with aortic valve prolapse...
2018: F1000Research
https://www.readbyqxmd.com/read/29764718/metabolic-syndrome-associates-with-left-atrial-dysfunction
#4
K Nyman, M Granér, M O Pentikäinen, J Lundbom, A Hakkarainen, R Sirén, M S Nieminen, M-R Taskinen, N Lundbom, K Lauerma
BACKGROUND AND AIMS: Obesity and metabolic syndrome (MetS) are risk factors of atrial fibrillation (AF), but limited data exist on their effect on left atrial (LA) function. The aim of the study was to evaluate the effects of cardiac, hepatic and intra-abdominal ectopic fat depots and cardiometabolic risk factors on LA function in non-diabetic male subjects. METHODS AND RESULTS: Myocardial and hepatic triglyceride contents were measured with 1.5T 1 H-magnetic resonance spectroscopy and LA and left ventricular function, visceral adipose tissue (VAT), subcutaneous adipose tissue (SAT), epicardial and pericardial fat by magnetic resonance imaging (MRI) in 33 men with MetS and 40 men without MetS...
February 21, 2018: Nutrition, Metabolism, and Cardiovascular Diseases: NMCD
https://www.readbyqxmd.com/read/29752376/effects-of-prolonged-spaceflight-on-atrial-size-atrial-electrophysiology-and-risk-of-atrial-fibrillation
#5
Htet W Khine, Katarina Steding-Ehrenborg, Jeffrey L Hastings, Jamie Kowal, James D Daniels, Richard L Page, Jeffery J Goldberger, Jason Ng, Beverley Adams-Huet, Michael W Bungo, Benjamin D Levine
BACKGROUND: The prevalence of atrial fibrillation (AF) in active astronauts is ≈5%, similar to the general population but at a younger age. Risk factors for AF include left atrial enlargement, increased number of premature atrial complexes, and certain parameters on signal-averaged electrocardiography, such as P-wave duration, root mean square voltage for the terminal 20 ms of the signal-averaged P wave, and P-wave amplitude. We aimed to evaluate changes in atrial structure, supraventricular beats, and atrial electrophysiology to determine whether spaceflight could increase the risk of AF...
May 2018: Circulation. Arrhythmia and Electrophysiology
https://www.readbyqxmd.com/read/29752195/prevalence-clinical-characteristics-and-outcome-of-atrial-functional-mitral-regurgitation-in-hospitalized-heart-failure-patients-with-atrial-fibrillation
#6
Chihiro Saito, Yuichiro Minami, Kotaro Arai, Shintaro Haruki, Yoshimi Yagishita, Kentaro Jujo, Kyomi Ashihara, Nobuhisa Hagiwara
BACKGROUND: Functional mitral regurgitation (MR) caused by reduced left ventricular ejection fraction (EF) and tethering, termed ventricular functional MR (VFMR), is associated with worse outcomes. Atrial functional MR (AFMR) caused by left atrial enlargement and annular dilatation was also recently described in patients with atrial fibrillation (AF). However, the clinical profiles of AFMR in hospitalized heart failure (HF) patients are unclear. We investigated the prevalence, clinical characteristics, and prognosis of AFMR in hospitalized HF patients with AF...
May 8, 2018: Journal of Cardiology
https://www.readbyqxmd.com/read/29697078/high-resolution-computerized-tomography-changes-in-diffuse-parenchymal-lung-disease-from-chronic-hypersensitivity-pneumonitis-related-to-bird-antigen
#7
Parthasarathi Bhattacharyya, Sanjukta Dasgupta, Mintu Paul, Dipanjan Saha, Sayoni Sengupta, Pinak Pani Bhattacharyya
Background: Chronic hypersensitivity pneumonitis (HP) is the most common cause of diffuse parenchymal lung disease (DPLD) in India. There is no data regarding the avian antigen exposure-associated DPLD from the country. Methods: Chronic HP from exposure to avian antigen was diagnosed when the high resolution computerized tomography (HRCT) showed features for HP and was supported by the history of exposure to pigeons, the presence of precipitin antibodies (IgG) to avian antigen in high titre with negative rheumatoid factor, antinuclear antibody, and no clinical clue for a collagen vascular disease...
May 2018: Lung India: Official Organ of Indian Chest Society
https://www.readbyqxmd.com/read/29686287/association-between-atrial-fibrillation-atrial-enlargement-and-left-ventricular-geometric-remodeling
#8
Yuta Seko, Takao Kato, Tetsuya Haruna, Toshiaki Izumi, Shoichi Miyamoto, Eisaku Nakane, Moriaki Inoko
This study investigated the relationship between atrial fibrillation (AF) and left ventricular (LV) geometric patterns in a hospital-based population in Japan. We retrospectively analyzed 4444 patients who had undergone simultaneous scheduled transthoracic echocardiography (TTE) and electrocardiography during 2013. A total of 430 patients who had findings of previous myocardial infarctions (n = 419) and without the data on body surface area (n = 11) were excluded from the study. We calculated the LV mass index (LVMI) and relative wall (RWT) and categorized 4014 patients into four groups as follows: normal geometry (n = 3046); concentric remodeling (normal LVMI and high RWT, n = 437); concentric hypertrophy (high LVMI and high RWT, n = 149); and eccentric remodeling (high LVMI and normal RWT, n = 382)...
April 23, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29684090/predictors-of-poor-outcome-in-patients-with-pulmonary-arterial-hypertension-a-single-center-study
#9
Emilia Stepnowska, Ewa Lewicka, Alicja Dąbrowska-Kugacka, Ludmiła Daniłowicz-Szymanowicz, Paweł Zagożdżon, Rafał Kamiński, Zuzanna Lewicka-Potocka, Paweł Miękus, Dariusz Kozłowski, Wojciech Potocki, Grzegorz Raczak
OBJECTIVES: Pulmonary arterial hypertension (PAH) is a rare disorder with unfavorable prognosis despite implementation of specific PAH-oriented therapy. The aim of the study was to define predictors of poor prognosis in patients from one center treated according to the Polish National Health Fund program. PATIENTS AND METHODS: Forty-seven consecutive patients (30 women; aged 39±17 years) with PAH diagnosis were enrolled to the study. Clinical assessment, laboratory measurements, electrocardiogram, echocardiography, 6-minute walk test, 24-hour Holter monitoring, cardiopulmonary exercise test and microvolt T-wave alternans test were performed during routine visits...
2018: PloS One
https://www.readbyqxmd.com/read/29679534/determinants-of-reverse-remodeling-of-the-left-atrium-following-transaortic-myectomy
#10
Anita Nguyen, Hartzell V Schaff, Rick A Nishimura, Joseph A Dearani, Jeffrey B Geske, Brian D Lahr, Steve R Ommen
BACKGROUND: In patients with hypertrophic cardiomyopathy (HCM), enlargement of the left atrium (LA) is associated with increased morbidity and mortality due to risk of atrial fibrillation (AF), stroke, and heart failure. In this study, we investigated whether LA reverse remodeling occurs following septal myectomy. METHODS: Between March 2007 and July 2015, 656 patients underwent myectomy at our institution and had pre- and postoperative transthoracic echocardiographic (TTE) recording of LA volume index (LAVI)...
April 18, 2018: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/29678339/usefulness-of-pulmonary-arterial-end-diastolic-forward-flow-late-after-tetralogy-of-fallot-repair-to-predict-a-restrictive-right-ventricle
#11
Shelby Kutty, Anne Marie Valente, Matthew T White, Kelsey Hickey, David A Danford, Andrew J Powell, Tal Geva
The functional significance of pulmonary arterial end-diastolic forward flow (EDFF) in patients with repaired tetralogy of Fallot (rTOF) is not fully understood, with conflicting reports regarding its associations with pulmonary regurgitation (PR), right ventricular (RV) size and function, and so-called restrictive RV physiology. To examine these associations, we retrospectively analyzed 399 patients with rTOF who had contemporaneous echocardiography (Echo) and cardiovascular magnetic resonance (CMR) studies...
March 7, 2018: American Journal of Cardiology
https://www.readbyqxmd.com/read/29659090/detection-of-intra-cardiac-thrombi-and-congestive-heart-failure-in-cats-using-computed-tomographic-angiography
#12
Kyle P Vititoe, Ryan C Fries, Stephen Joslyn, Laura E Selmic, Mark Howes, Jordan P Vitt, Robert T O'Brien
Arterial thromboembolism is a life-threatening condition in cats most commonly secondary to cardiac disease. Echocardiography is the reference standard to evaluate for presence of a thrombus. In humans, computed tomographic (CT) angiography is becoming widely used to detect left atrial thrombi precluding the use of sedation. The purpose of this prospective, controlled, methods comparison pilot study was threefold: (1) describe new CT angiography protocol used in awake cats with cardiac disease and congestive heart failure; (2) determine accuracy of continuous and dynamic acquisition CT angiography to identify and characterize cardiac thrombi from spontaneous echocardiographic contrast using transthoracic echocardiography as our reference standard; (3) identify known negative prognostic factors and comorbidities of the thorax that CT angiography may provide that complement or supersede echocardiographic examination...
April 16, 2018: Veterinary Radiology & Ultrasound
https://www.readbyqxmd.com/read/29652656/electrocardiogram-abnormalities-related-to-anti-malarials-in-systemic-lupus-erythematosus
#13
Taneisha K McGhie, Paula Harvey, Jiandong Su, Nicole Anderson, George Tomlinson, Zahi Touma
OBJECTIVES: Cardiotoxicity with potential conduction/structural abnormalities on electrocardiogram (ECG) have been reported with anti-malarial (AM). We aimed to study whether cumulative AM is associated with ECG abnormalities. METHODS: A standard resting supine ECG was performed on consecutive patients attending the Lupus Clinic since 2012. ECG abnormalities were grouped into structural [left ventricular hypertrophy or atrial enlargement] and conduction abnormalities [prolonged corrected QT interval (QTc), short PR interval, left bundle branch block (LBBB), right bundle branch block (RBBB) and atrioventricular block (AVB), bradycardia, tachycardia, premature atrial complex, ectopic atrial rhythm, atrial fibrillation, premature ventricular complex and ventricular bigeminy]...
April 13, 2018: Clinical and Experimental Rheumatology
https://www.readbyqxmd.com/read/29605015/left-atrial-thrombus-and-dense-spontaneous-echocardiographic-contrast-in-patients-on-continuous-direct-oral-anticoagulant-therapy-undergoing-catheter-ablation-of-atrial-fibrillation-comparison-of-dabigatran-rivaroxaban-and-apixaban
#14
Michael Wu, James Gabriels, Mohammad Khan, Nada Shaban, Salvatore D'Amato, Christopher F Liu, Steven M Markowitz, James E Ip, George Thomas, Parmanand Singh, Bruce Lerman, Apoor Patel, Jim W Cheung
BACKGROUND: Left atrial thrombus (LAT) and dense spontaneous echocardiographic contrast (SEC) detected by transesophageal echocardiography (TEE) in patients on continuous direct oral anticoagulants (DOAC) therapy before catheter ablation of atrial fibrillation (AF) or atrial flutter (AFL) have been described. OBJECTIVE: We sought to compare rates of TEE-detected LAT and dense SEC among patients taking different DOACs. METHODS: We evaluated 609 consecutive patients from 3 tertiary hospitals (median age 65 years; interquartile range 58-71 years; 436 (72%) men) who were on ≥4 weeks of continuous DOAC therapy (dabigatran, n = 166 [27%]; rivaroxaban, n = 257 [42%]; or apixaban, n = 186 [31%]) undergoing TEE before catheter ablation of AF/AFL...
April 2018: Heart Rhythm: the Official Journal of the Heart Rhythm Society
https://www.readbyqxmd.com/read/29587523/assessment-of-electrocardiographic-criteria-of-left-atrial-enlargement
#15
Mahesh Kumar Batra, Atif Khan, Fawad Farooq, Tariq Masood, Musa Karim
Background Left atrial enlargement is considered to be a robust, strong, and widely acceptable indicator of cardiovascular outcomes. Echocardiography is the gold standard for measurement of left atrial size, but electrocardiography can be simple, cost-effective, and noninvasive in clinical practice. This study was undertaken to assess the diagnostic accuracy of an established electrocardiographic criterion for left atrial enlargement, taking 2-dimensional echocardiography as the gold-standard technique. Methods A cross-sectional study was conducted on 146 consecutively selected patients with the complaints of dyspnea and palpitation and with a murmur detected on clinical examination, from September 10, 2016 to February 10, 2017...
January 1, 2018: Asian Cardiovascular & Thoracic Annals
https://www.readbyqxmd.com/read/29579615/second-generation-cryoballoon-ablation-as-a-first-line-treatment-of-symptomatic-atrial-fibrillation-two-year-outcome-and-predictors-of-recurrence-after-a-single-procedure
#16
Ersan Akkaya, Alexander Berkowitsch, Sergej Zaltsberg, Harald Greiss, Christian W Hamm, Johannes Sperzel, Thomas Neumann, Malte Kuniss
INTRODUCTION: Antiarrhythmic drug (AAD) therapy of patients with atrial fibrillation (AF) has limitations. We investigated the 2-year outcome and pre-procedural predictors of recurrence for first-line catheter ablation using the second-generation cryoballoon (CB-Adv) in a large cohort of patients with symptomatic AF. METHODS AND RESULTS: For this prospective observational study, we enrolled 457 patients with symptomatic AF (278 paroxysmal, 179 persistent) who had no history of AAD use and who underwent pulmonary vein isolation (PVI) with the CB-Adv at our institution...
May 15, 2018: International Journal of Cardiology
https://www.readbyqxmd.com/read/29575400/regression-of-left-atrial-diameter-after-kidney-transplantation-is-associated-with-prolonged-survival-an-observational-study
#17
Florina Regele, Alexander Kainz, Michael Kammer, Arno Beer, Regina Steringer-Mascherbauer, Thomas Binder, Rainer Oberbauer
Renal transplantation reduces the dramatically elevated risk of cardiovascular death in dialysis patients. We previously showed that left atrial diameter before transplantation predicts cardiovascular and overall mortality. Now, we investigated the association of changes in cardiac morphology after transplantation and mortality. We retrospectively analyzed data from the Austrian transplant repository using multivariable Cox and competing risk models and multivariable logistic regression for the prediction of changes in cardiac morphology...
March 25, 2018: Transplant International: Official Journal of the European Society for Organ Transplantation
https://www.readbyqxmd.com/read/29574291/five-chambered-heart-case-of-a-huge-left-atrial-appendage-aneurysm
#18
Mohammad Hassan Nezafati, Hossein Nazari Hayanou, Mahdi Kahrom, Alireza Khooei, Pouya Nezafati
Aneurysmal enlargement of the left atrial appendage is an extremely rare pathology and can predispose to adverse events, including cardiac arrest, respiratory distress, arrhythmia, heart failure, systemic thromboembolism, or rupture. It is usually diagnosed incidentally or after the occurrence of atrial tachyarrhythmias or thrombotic events in the second to fourth decades of life. We describe a rare case of a symptomatic giant congenital left atrial appendage aneurysm (LAAA) in a 26-year-old man presenting with neurologic event, in whom surgical resection of the aneurysm was successfully performed...
March 6, 2018: Cardiovascular Pathology: the Official Journal of the Society for Cardiovascular Pathology
https://www.readbyqxmd.com/read/29570509/impact-of-obstructive-sleep-apnea-on-cardiac-organ-damage-in-patients-with-acute-ischemic-stroke
#19
Paola Mattaliano, Carolina Lombardi, Davide Sangalli, Andrea Faini, Barbara Corrà, Laura Adobbati, Giovanna Branzi, Davide Mariani, Vincenzo Silani, Gianfranco Parati
BACKGROUND AND PURPOSE: Both obstructive sleep apnea (OSA) and cardiac organ damage have a crucial role in acute ischemic stroke. Our aim is to explore the relationship between OSA and cardiac organ damage in acute stroke patients. METHODS: A total of 130 consecutive patients with acute ischemic stroke were enrolled. Patients underwent full multichannel 24-h polysomnography for evaluation of OSA and echocardiography to evaluate left ventricle (LV) mass index (LV mass/BSA, LV mass/height), thickness of interventricular septum (IVS) and posterior wall (LVPW), LV ejection fraction and left atrium enlargement...
March 22, 2018: Journal of Hypertension
https://www.readbyqxmd.com/read/29569424/left-atrial-volume-in-patients-with-her2-positive-breast-cancer-one-step-further-to-predict-trastuzumab-related-cardiotoxicity
#20
Corinna Bergamini, Giulia Dolci, Andrea Rossi, Flavia Torelli, Luca Ghiselli, Laura Trevisani, Giulia Vinco, Stella Truong, Francesca La Russa, Giorgio Golia, Annamaria Molino, Giovanni Benfari, Flavio Luciano Ribichini
BACKGROUND: Trastuzumab (TZ) therapy requires careful monitoring of left ventricular (LV) ejection fraction (LVEF) because it can be potentially cardiotoxic. However, LVEF is an imperfect parameter and there is a need to find other variables to predict cardiac dysfunction early. Left atrium (LA) enlargement has proven to be a powerful predictor of adverse outcomes in several disease entities. HYPOTHESIS: Baseline LA volume enlargement might predict TZ-related LV dysfunction...
March 22, 2018: Clinical Cardiology
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