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https://www.readbyqxmd.com/read/28239349/fear-and-uncertainty-do-not-influence-reported-willingness-to-undergo-lumbar-punctures-in-a-u-s-multi-cultural-cohort
#1
Dobromira Z Tsvetkova, Sharon H Bergquist, Monica W Parker, Thomas L Jarrett, Jennifer C Howell, Kelly D Watts, Alexander Kollhoff, David L Roberts, William T Hu
Cerebrospinal fluid (CSF) biomarkers for Alzheimer's disease and related disorders can provide early and accurate prediction of underlying neuropathology even when the clinical symptoms are mild, but lumbar punctures (LP) to obtain CSF can be perceived as frightening and invasive. We previously demonstrated that this negative perception of the LP is strongly associated with a negative LP experience in terms of discomfort and complications, but it is not known what factors can lead to a negative perception of the LP...
2017: Frontiers in Aging Neuroscience
https://www.readbyqxmd.com/read/28239262/the-well-being-valuation-model-a-method-for-monetizing-the-nonmarket-good-of-individual-well-being
#2
James A Sidney, Ashlin Jones, Carter Coberley, James E Pope, Aaron Wells
The objective of this research is to advance the evaluation and monetization of well-being improvement programs, offered by population health management companies, by presenting a novel method that robustly monetizes the entirety of well-being improvement within a population. This was achieved by utilizing two employers' well-being assessments with medical and pharmacy administrative claims (2010-2011) across a large national employer (n = 50,647) and regional employer (n = 6170) data sets. This retrospective study sought to monetize both direct and indirect value of well-being improvement across a population whose medical costs are covered by an employer, insurer, and/or government entity...
2017: Health Services & Outcomes Research Methodology
https://www.readbyqxmd.com/read/28238992/characteristics-of-effective-colorectal-cancer-screening-navigation-programs-in-federally-qualified-health-centers-a-systematic-review
#3
Jermy-Leigh B Domingo, Kathryn L Braun
In the U.S., colorectal cancer (CRC) incidence and mortality have declined due to screening and improvements in early detection; however, racial/ethnic disparities in screening and mortality persist. Patient navigation has been shown to be effective in increasing CRC screening prevalence. This systematic review answered three questions about navigation in federally qualified community health centers (FQHCs): 1) Which navigation activities increased CRC screening prevalence? 2) What were the challenges to implementing these programs in FQHCs? 3) Which clinic protocols supported screening completion? Findings suggest that navigation services must be tailored to the specific screening test provided...
2017: Journal of Health Care for the Poor and Underserved
https://www.readbyqxmd.com/read/28238804/challenges-in-diagnosing-and-treating-snakebites-in-a-rural-population-of-tamil-nadu-india-the-views-of-clinicians
#4
Harry F Williams, Rajendran Vaiyapuri, Prabu Gajjeraman, Gail Hutchinson, Jonathan M Gibbins, Andrew Bicknell, Sakthivel Vaiyapuri
Snakebites cause death, disability and economic devastation to their victims, people who live almost exclusively in rural areas. Annually an estimated two million venomous bites cause as many as 100,000 deaths worldwide as well as hundreds of thousands of deformities and amputations. Recent studies suggest that India has the highest incidence of snakebite and associated deaths worldwide. In this study, we interviewed 25 hospital-based clinicians who regularly treat snakebites in Tamil Nadu, India, in order to gauge their opinions and views on the diagnostic tools and treatment methods available at that time, the difficulties encountered in treating snakebites and improvements to snakebite management protocols they deem necessary...
February 23, 2017: Toxicon: Official Journal of the International Society on Toxinology
https://www.readbyqxmd.com/read/28238106/a-critical-assessment-of-early-warning-score-records-in-168-000-patients
#5
Niels Egholm Pedersen, Lars Simon Rasmussen, John Asger Petersen, Thomas Alexander Gerds, Doris Østergaard, Anne Lippert
The national early warning score (NEWS) is recommended to detect deterioration in hospitalised patients. In 2013, a NEWS-based system was introduced in a hospital service with over 250,000 annual admissions, generating large amounts of NEWS data. The quality of such data has not been described. We critically assessed NEWS data recorded over 12 months. This observational study included NEWS records from adult inpatients hospitalized in the Capital Region of Denmark during 2014. Physiological variables and the use of supplementary oxygen (NEWS variables) were recorded...
February 25, 2017: Journal of Clinical Monitoring and Computing
https://www.readbyqxmd.com/read/28237961/healthcare-usage-and-economic-impact-of-non-treated-obesity-in-italy-findings-from-a-retrospective-administrative-and-clinical-database-analysis
#6
Annamaria Colao, Marcello Lucchese, Monica D'Adamo, Silvia Savastano, Enrico Facchiano, Chiara Veronesi, Valerio Blini, Luca Degli Esposti, Paolo Sbraccia
OBJECTIVES: Investigate the prevalence of obesity in Italy and examine its resource consumption and economic impact on the Italian national healthcare system (NHS). DESIGN: Retrospective, observational and real-life study. SETTING: Data from three health units from Northern (Bergamo, Lombardy), Central (Grosseto, Tuscany) and Southern (Naples, Campania) Italy. PARTICIPANTS: All patients aged ≥18 years with at least one recorded body mass index (BMI) measurement between 1 January 2009 and 31 December 2012 were included...
February 24, 2017: BMJ Open
https://www.readbyqxmd.com/read/28237957/performance-curves-of-medical-researchers-during-their-career-analysis-of-scientific-production-from-a-retrospective-cohort
#7
Antoine Duclos, Eléonore Herquelot, Stéphanie Polazzi, Muriel Malbezin, Olivier Claris
OBJECTIVES: To establish the pattern of change in individual scientific production over the career of medical researchers. DESIGN: Retrospective cohort based on prospectively collected data in a hospital information system. SETTING: Multicentre university hospital in France. PARTICIPANTS: Two distinct populations of 1835 researchers (full professors vs non-academic physicians) having produced 44 723 publications between 1995 and 2014...
February 24, 2017: BMJ Open
https://www.readbyqxmd.com/read/28237240/antimicrobial-reduction-measures-applied-in-danish-pig-herds-following-the-introduction-of-the-yellow-card-antimicrobial-scheme
#8
Nana Dupont, Line Hummelmose Diness, Mette Fertner, Charlotte Sonne Kristensen, Helle Stege
Following introduction of the antimicrobial restrictive "Yellow Card Scheme" in summer 2010, a rapid decrease in the Danish national pig antimicrobial consumption was observed. The aims of this study were to (i) investigate which measures had been implemented to reduce the antimicrobial consumption according to farmers and veterinarians and (ii) where possible, investigate if said measures were reflected in the herds' antimicrobial purchase data. Based on national register data from VetStat and the Central Husbandry Register, the study population was selected among Danish pig herds which had decreased their annual antimicrobial consumption with ≥10% following the introduction of the Yellow Card Scheme comparing June 1, 2009-May 31, 2010 to June 1, 2010-May 31, 2011...
March 1, 2017: Preventive Veterinary Medicine
https://www.readbyqxmd.com/read/28230650/acr-appropriateness-criteria%C3%A2-resectable-pancreatic-cancer
#9
William E Jones, W Waren Suh, May Abdel-Wahab, Ross A Abrams, Nilofer Azad, Prajnan Das, Jadranka Dragovic, Karyn A Goodman, Salma K Jabbour, Andre A Konski, Albert C Koong, Rachit Kumar, Percy Lee, Timothy M Pawlik, William Small, Joseph M Herman
Management of resectable pancreatic adenocarcinoma continues to present a challenge due to a paucity of high-quality randomized studies. Administration of adjuvant chemotherapy is widely accepted due to the high risk of systemic spread associated with pancreatic adenocarcinoma, but the role of radiation therapy is less clear. This paper reviews literature associated with resectable pancreatic cancer to include prognostic factors to aid in the selection of patients appropriate for adjuvant therapies. The American College of Radiology Appropriateness Criteria are evidence-based guidelines for specific clinical conditions that are reviewed annually by a multidisciplinary expert panel...
February 22, 2017: American Journal of Clinical Oncology
https://www.readbyqxmd.com/read/28230459/estimated-cost-effectiveness-cost-benefit-and-risk-reduction-associated-with-an-endocrinologist-pharmacist-diabetes-intense-medical-management-tune-up-clinic
#10
Jan D Hirsch, Mark Bounthavong, Anisa Arjmand, David R Ha, Christine L Cadiz, Andrew Zimmerman, Heather Ourth, Anthony P Morreale, Steven V Edelman, Candis M Morello
BACKGROUND: In 2012 U.S. diabetes costs were estimated to be $245 billion, with $176 billion related to direct diabetes treatment and associated complications. Although a few studies have reported positive glycemic and economic benefits for diabetes patients treated under primary care physician (PCP)-pharmacist collaborative practice models, no studies have evaluated the cost-effectiveness of an endocrinologist-pharmacist collaborative practice model treating complex diabetes patients versus usual PCP care for similar patients...
March 2017: Journal of Managed Care & Specialty Pharmacy
https://www.readbyqxmd.com/read/28230457/comparative-effectiveness-of-rapid-acting-insulins-in-adults-with-diabetes
#11
Patrick N Racsa, Yunus Meah, Jeffrey J Ellis, Kimberly R Saverno
BACKGROUND: Although there are a variety of insulin products and new delivery modalities available, the absence of direct clinical and economic comparisons can make treatment planning and formulary decision making difficult. Direct comparisons between insulin aspart and insulin lispro from a large heterogeneous population are not available. OBJECTIVE: To assess differences in clinical outcomes, medication adherence, utilization, and total health care costs between aspart and lispro and vial versus pen modalities for administering these short-acting insulin analogs...
March 2017: Journal of Managed Care & Specialty Pharmacy
https://www.readbyqxmd.com/read/28230454/adherence-persistence-and-health-care-costs-for-patients-receiving-dipeptidyl-peptidase-4-inhibitors
#12
Karen L Rascati, Karen Worley, Yunus Meah, Damian Everhart
BACKGROUND: The dipeptidyl peptidase-4 (DPP-4) inhibitors are among the newer, yet more established, classes of diabetes medications. OBJECTIVE: To compare adherence, persistence, and health care costs among patients taking DPP-4 inhibitors. METHODS: Claims were extracted from Humana Medicare Advantage Prescription Drug (MAPD) or commercial plans for patients aged > 18 years with ≥ 1 prescription filled for a DPP-4 inhibitor between July 1, 2011, and March 31, 2013...
March 2017: Journal of Managed Care & Specialty Pharmacy
https://www.readbyqxmd.com/read/28230452/prescription-drug-utilization-and-reimbursement-increased-following-state-medicaid-expansion-in-2014
#13
Nirosha Mahendraratnam, Stacie B Dusetzina, Joel F Farley
BACKGROUND: The Affordable Care Act (ACA) expanded health care and medication insurance coverage through Medicaid expansion in select states. Expansion has the potential to increase the availability of health services to patients, including prescription medications. However, limited studies have examined how expansion affected prescription drug utilization and reimbursement. OBJECTIVE: To compare prescription drug utilization (number of prescriptions filled) and reimbursement trends between states that did and did not expand Medicaid coverage in 2014, while accounting for known effects of expansion on Medicaid enrollment...
March 2017: Journal of Managed Care & Specialty Pharmacy
https://www.readbyqxmd.com/read/28228660/estimating-the-economic-consequences-of-an-increased-medication-adherence-due-to-a-potential-improvement-in-the-inhaler-technique-with-spiromax-%C3%A2-compared-with-turbuhaler-%C3%A2-in-patients-with-moderate-to-severe-chronic-obstructive-pulmonary-disease-in-spain
#14
Josep Darbà, Gabriela Ramírez, Juan L García-Rivero, Sagrario Mayoralas, José Francisco Pascual, Diego Vargas, Adi Bijedic
OBJECTIVE: The objective of this study was to estimate the economic impact of the introduction of DuoResp(®) Spiromax(®), budesonide/formoterol fixed-dose combination (FDC), focusing on an increase in medication adherence due to an enhancement of the inhalation technique for the treatment of COPD patients in Spain and 5 regions including Andalusia, Catalonia, Galicia, Madrid, and Valencia. METHODS: A 4-year budget impact model was developed for the time period of 2015-2018...
2017: ClinicoEconomics and Outcomes Research: CEOR
https://www.readbyqxmd.com/read/28228485/probability-of-vertical-transmission-of-chlamydia-trachomatis-estimated-from-national-registry-data
#15
Minna Honkila, Erika Wikström, Marjo Renko, Heljä-Marja Surcel, Tytti Pokka, Irma Ikäheimo, Matti Uhari, Terhi Tapiainen
OBJECTIVES: Chlamydia trachomatis colonisation is common in pregnant women, and it has been claimed that mother-to-child transmission may occur in 10%-70% of deliveries. C. trachomatis infections are nevertheless rarely encountered in infants in clinical practice. In order to evaluate the reason for this discrepancy, we designed a nationwide study of the C. trachomatis vertical transmission. METHODS: Children with a possible C. trachomatis infection were identified from two national health registries in 1996-2011...
February 21, 2017: Sexually Transmitted Infections
https://www.readbyqxmd.com/read/28226405/comparative-effectiveness-of-long-acting-beta2-agonist-combined-with-a-long-acting-muscarinic-antagonist-or-inhaled-corticosteroid-in-chronic-obstructive-pulmonary-disease
#16
Jennifer C Samp, Min J Joo, Glen T Schumock, Gregory S Calip, A Simon Pickard, Todd A Lee
INTRODUCTION: Several dual bronchodilator fixed dose inhaler medications were recently approved for the treatment of chronic obstructive pulmonary disease (COPD). These products combine a long-acting beta2 -agonist (LABA) and long-acting muscarinic antagonist (LAMA). In clinical trials, the separate mechanisms of the bronchodilators resulted in improved lung function. COPD treatment guidelines currently recommend combination LABA/LAMA as alternative therapy to combination LABA/ inhaled corticosteroid (ICS)...
February 22, 2017: Pharmacotherapy
https://www.readbyqxmd.com/read/28226204/brief-report-current-status-of-pathologic-examinations-in-korea-2011-2015-based-on-the-health-insurance-review-and-assessment-service-dataset
#17
Sun-Ju Byeon
Background: Pathologic examinations play an important role in medical services. Until recently, the overall status of pathologic examinations in Korea has not been identified. I conducted a nationwide survey of pathologic examination status using the insurance reimbursements (IRs) dataset from the Health Insurance Review and Assessment Service (HIRA). The aims of this study were to estimate current pathologic examination status in Korea and to provide information for future resource arrangement in the pathology era...
February 22, 2017: Journal of Pathology and Translational Medicine
https://www.readbyqxmd.com/read/28225461/faculty-development-for-medical-school-community-based-faculty-a-council-of-academic-family-medicine-educational-research-alliance-study-exploring-institutional-requirements-and-challenges
#18
Joanna Drowos, Suzanne Baker, Suzanne Leonard Harrison, Suzanne Minor, Alexander W Chessman, Dennis Baker
PURPOSE: Community-based faculty play a large role in training medical students nationwide and require faculty development. The authors hypothesized that positive relationships exist between clerkships paying preceptors and requiring faculty development, and between protected clerkship directors' time and delivering face-to-face preceptor training, as well as with the number or length of community-based preceptor visits. Through under standing the quantity, delivery methods, barriers, and institutional support for faculty development provided to community-based preceptors teaching in family medicine clerkships, best practices can be developed...
February 21, 2017: Academic Medicine: Journal of the Association of American Medical Colleges
https://www.readbyqxmd.com/read/28224724/economic-and-social-impact-of-diabetes-mellitus-in-a-low-income-country-a-case-control-study-in-sudan
#19
Hind Elrayah-Eliadarous, Claes-Göran Östensson, Mohamed Eltom, Pia Johansson, Vibeke Sparring, Rolf Wahlström
AIMS: Diabetes mellitus accounts for 11% of total health expenditures worldwide, and the majority of all persons with diabetes live in low- and middle-income countries. This study examined the economic and social impact attributed to diabetes in Sudan by calculating out-of-pocket medical expenditures and the health and social impact of the disease for persons with diabetes (n = 375) and their families, compared to a non-diabetic control group (n = 375), matched for age, sex and residence area...
February 22, 2017: Journal of Diabetes
https://www.readbyqxmd.com/read/28224283/health-service-use-costs-and-adverse-events-associated-with-potentially-inappropriate-medication-in-old-age-in-germany-retrospective-matched-cohort-study
#20
Dirk Heider, Herbert Matschinger, Andreas D Meid, Renate Quinzler, Jürgen-Bernhard Adler, Christian Günster, Walter E Haefeli, Hans-Helmut König
BACKGROUND: Drug-related problems are an important healthcare safety concern in the growing population of older people. Prescription of potentially inappropriate medication (PIM) is one aspect of this concern that is considered to increase the risk of adverse health outcomes. OBJECTIVE: The aim of the Health Economics of Potentially Inappropriate Medication (HEPIME) study was to analyze the association between the prescription of PIMs according to the German PRISCUS list and healthcare utilization, healthcare costs, and the occurrence of adverse events in old age...
February 21, 2017: Drugs & Aging
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