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Randomized Control Study

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https://www.readbyqxmd.com/read/28750504/does-myofascial-and-trigger-point-treatment-reduce-pain-and-analgesic-intake-in-patients-undergoing-onabotulinumtoxina-injection-due-to-chronic-intractable-migraine-a-pilot-single-blind-randomized-controlled-trial
#1
Marialuisa Gandolfi, Christian Geroin, Nicola Valè, Fabio Marchioretto, Andrea Turrina, Eleonora Dimitrova, Stefano Tamburin, Anna Serina, Paola Castellazzi, Andrea Meschieri, François Ricard, Leopold Saltuari, Alessandro Picelli, Nicola Smania
BACKGROUND: Chronic migraine is a disabling disorder associated with myofascial and trigger point disorders in the neck. Pharmacological management is the first line of treatment; however, rehabilitation procedures aimed at lessening symptoms of myofascial and trigger point disorders may add value in the management of headache symptoms. AIM: To evaluate the feasibility of myofascial and trigger point treatment in chronic migraine patients receiving prophylactic treatment with onabotulinumtoxinA...
July 27, 2017: European Journal of Physical and Rehabilitation Medicine
https://www.readbyqxmd.com/read/28750481/aqueous-shunts-for-glaucoma
#2
REVIEW
Victoria L Tseng, Anne L Coleman, Melinda Y Chang, Joseph Caprioli
BACKGROUND: Aqueous shunts are employed to control intraocular pressure (IOP) for people with primary or secondary glaucomas who fail or are not candidates for standard surgery. OBJECTIVES: To assess the effectiveness and safety of aqueous shunts for reducing IOP in glaucoma compared with standard surgery, another type of aqueous shunt, or modification to the aqueous shunt procedure. SEARCH METHODS: We searched CENTRAL (which contains the Cochrane Eyes and Vision Trials Register) (2016, Issue 8), MEDLINE Ovid (1946 to August 2016), Embase...
July 28, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28750366/prophylactic-treatment-with-cerium-oxide-nanoparticles-attenuate-hepatic-ischemia-reperfusion-injury-in-sprague-dawley-rats
#3
Nandini D P K Manne, Ravikumar Arvapalli, Vincent A Graffeo, Venkata V K Bandarupalli, Tolou Shokuhfar, Sweetu Patel, Kevin M Rice, Gautam Kumar Ginjupalli, Eric R Blough
BACKGROUND: Hepatic ischemia reperfusion is one the main causes for graft failure following transplantation. Although, the molecular events that lead to hepatic failure following ischemia reperfusion (IR) are diverse and complex, previous studies have shown that excessive formation of reactive oxygen species (ROS) are responsible for hepatic IR injury. Cerium oxide (CeO2) nanoparticles have been previously shown to act as an anti-oxidant and anti-inflammatory agent. Here, we evaluated the protective effects of CeO2 nanoparticles on hepatic ischemia reperfusion injury...
July 27, 2017: Cellular Physiology and Biochemistry
https://www.readbyqxmd.com/read/28750356/combined-calcitriol-and-menadione-reduces-experimental-murine-triple-negative-breast-tumor
#4
Luciana Bohl, Solange Guizzardi, Valeria Rodríguez, Lucila Hinrichsen, Viviana Rozados, David Cremonezzi, Nori Tolosa de Talamoni, Gabriela Picotto
BACKGROUND: Calcitriol (D) or 1,25(OH)2D3 inhibits the growth of several tumor cells including breast cancer cells, by activating cell death pathways. Menadione (MEN), a glutathione-depleting compound, may be used to potentiate the antiproliferative actions of D on cancer cells. We have previously shown in vitro that MEN improved D-induced growth arrest on breast cancer cell lines, inducing oxidative stress and DNA damage via ROS generation. Treatment with MEN+D resulted more effective than D or MEN alone...
July 24, 2017: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/28750332/the-effect-of-temperature-in-the-range-of-0-8-to-4%C3%A2-c-on-lamb-meat-color-stability
#5
Xin Li, Yan Zhang, Zheng Li, Meng Li, Yongfeng Liu, Dequan Zhang
This study investigated effects of controlled freezing point storage (CFPS, -0.8°C) on lamb color stability compared with storage at 4°C (control). The muscle samples (n=5) of longissimus thoracis et lumborum from both carcass sides were assigned randomly to the two storage treatments and stored for 10days. The a(⁎), b(⁎), R630/580 and Chroma values of samples stored in CFPS were significantly higher than that of samples in control from day 2 to day 10 (P<0.05). Higher relative content of oxymyoglobin but lower relative content of metmyoglobin were observed in samples stored in CFPS treatment than those in control over 10days of storage (P<0...
July 13, 2017: Meat Science
https://www.readbyqxmd.com/read/28750310/manual-therapy-exercise-therapy-or-combined-treatment-in-the-management-of-adult-neck-pain-a-systematic-review-and-meta-analysis
#6
REVIEW
Ken Fredin, Håvard Lorås
BACKGROUND: Neck pain is a common and often disabling musculoskeletal condition. Two therapies frequently prescribed for its management are manual therapy (MT) and exercise therapy (ET), and combining these treatment approaches are common. OBJECTIVE: To assess whether or not combined treatment consisting of MT and ET is more effective than either therapy alone in relieving pain and improving function in adult patients with grade I-II neck pain. DESIGN: Systematic review with meta-analysis...
July 21, 2017: Musculoskeletal Science & Practice
https://www.readbyqxmd.com/read/28750232/effects-of-chair-yoga-therapy-on-physical-fitness-in-patients-with-psychiatric-disorders-a-12-week-single-blind-randomized-controlled-trial
#7
Saeko Ikai, Hiroyuki Uchida, Yuya Mizuno, Hideaki Tani, Maki Nagaoka, Kenichi Tsunoda, Masaru Mimura, Takefumi Suzuki
INTRODUCTION: Since falls may lead to fractures and have serious, potentially fatal outcomes, prevention of falls is an urgent public health issue. We examined the effects of chair yoga therapy on physical fitness among psychiatric patients in order to reduce the risk of falls, which has not been previously reported in the literature. METHODS: In this 12-week single-blind randomized controlled trial with a 6-week follow-up, inpatients with mixed psychiatric diagnoses were randomly assigned to either chair yoga therapy in addition to ongoing treatment, or treatment-as-usual...
July 19, 2017: Journal of Psychiatric Research
https://www.readbyqxmd.com/read/28750220/effects-of-medicinal-food-plants-on-impaired-glucose-tolerance-a-systematic-review-of-randomized-controlled-trials
#8
REVIEW
A Demmers, H Korthout, F S van Etten-Jamaludin, F Kortekaas, J M Maaskant
BACKGROUND: The objective of this systematic review was to assess available scientific data on the efficacy and safety of medicinal food plants for the treatment of impaired glucose tolerance. METHODS: We included randomized controlled trials (RCTs) with a minimum follow-up period of 6weeks. The diagnosis was determined by fasting plasma glucose values after two-hour oral glucose tolerance testing (OGTT). Two authors independently extracted data and evaluated bias...
June 13, 2017: Diabetes Research and Clinical Practice
https://www.readbyqxmd.com/read/28750216/efficacy-of-low-carbohydrate-diet-for-type-2-diabetes-mellitus-management-a-systematic-review-and-meta-analysis-of-randomized-controlled-trials
#9
REVIEW
Yan Meng, Hao Bai, Shijun Wang, Zhaoping Li, Qian Wang, Liyong Chen
AIMS: The objective of this systematic review and meta-analysis is to assess the efficacy of Low Carbohydrate Diet (LCD) compared with a normal or high carbohydrate diet in patients with type 2 diabetes. METHODS: We searched MEDLINE, EMBASE, and Cochrane Library database for randomized controlled trials. Researches which reported the change in weight loss, blood glucose, and blood lipid levels were included. RESULTS: A total of 9 studies with 734 patients with diabetes were included...
July 8, 2017: Diabetes Research and Clinical Practice
https://www.readbyqxmd.com/read/28750153/safety-and-efficacy-of-dual-wavelength-laser-1064-nm-595-nm-for-treatment-of-non-treated-port-wine-stains
#10
Tianyou Wang, Da Chen, Jingyan Yang, Gang Ma, Wenxin Yu, Xiaoxi Lin
BACKGROUND: Patients with port-wine stain (PWS) suffer physically and psychologically because of the high incidence (0.3%-0.5%) of the disease. Pulsed dye laser (PDL) at 595 nm is the gold standard of the treatment for PWS. Nevertheless, clinicians intend to determine whether the dual wavelength laser (DWL) (595 nm PDL + 1064 nm Nd:YAG) is an adequate choice in the treatment of non-treated PWS. This study is the first prospective within-patient controlled research seeking to investigate the safety and efficacy of DWL for the treatment of non-treated PWS...
July 27, 2017: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/28750145/severity-assessments-used-for-inclusion-criteria-and-baseline-severity-evaluation-in-atopic-dermatitis-clinical-trials-a-systematic-review
#11
Rishi Chopra, Paras P Vakharia, Eric L Simpson, Amy S Paller, Jonathan I Silverberg
BACKGROUND: Numerous inclusion criteria and baseline severity assessments are used in clinical trials of atopic dermatitis (AD), which may limit comparison of results. OBJECTIVE: We sought to characterize the inclusion criteria and baseline severity assessments used in randomized controlled trials (RCT) of AD internationally. METHODS: We performed a systematic review of RCT with a pharmacological intervention from 2007-2016. Cochrane Library, EMBASE, GREAT, LILACS, MEDLINE and Scopus were searched...
July 27, 2017: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/28750109/comparison-of-fixed-dental-prostheses-with-zirconia-and-metal-frameworks-five-year-results-of-a-randomized-controlled-clinical-trial
#12
Irena Sailer, Marc Balmer, Hüsler Jürg, Christoph Hans Franz Hämmerle, Sarah Känel, Daniel Stefan Thoma
PURPOSE: The aim of this study was to test whether posterior zirconia-ceramic (ZC) and metal-ceramic (MC) fixed dental prostheses (FDPs) exhibit similar survival and technical/biologic complication rates. MATERIALS AND METHODS: A total of 58 patients in need of 76 posterior FDPs were randomly assigned to receive 40 ZC and 36 MC FDPs. The restorations were examined at baseline (cementation) and yearly for 5 years. Technical and biologic outcomes were compared. The independent treatment groups were compared with nonparametric Mann-Whitney test for metric variables and with Fisher exact test for categoric data...
July 27, 2017: International Journal of Prosthodontics
https://www.readbyqxmd.com/read/28750067/the-dissemination-of-motivational-interviewing-in-swedish-county-councils-results-of-a-randomized-controlled-trial
#13
Maria Beckman, Lars Forsberg, Helena Lindqvist, Margarita Diez, Johanna Enö Persson, Ata Ghaderi
OBJECTIVE: A significant number of Swedish practitioners are offered workshop trainings in motivational interviewing through community-based implementation programs. The objective of this randomized controlled trial was to evaluate to what extent the practitioners acquire and retain skills from additional supervision consisting of feedback based on monitoring of practice. MATERIALS AND METHODS: A total of 174 practitioners in five county councils across Sweden were randomized to one of the study's two groups: 1) Regular county council workshop training, 2) Regular county council workshop training followed by six sessions of supervision...
2017: PloS One
https://www.readbyqxmd.com/read/28750015/accuracy-of-self-collected-vaginal-dry-swabs-using-the-xpert-human-papillomavirus-assay
#14
Rosa Catarino, Pierre Vassilakos, Aline Bilancioni, Stéphanie Bougel, Meriem Boukrid, Ulrike Meyer-Hamme, Patrick Petignat
BACKGROUND: Polymerase chain reaction-based Xpert human papillomavirus (HPV) assay is a rapid test that detects high-risk HPV (hrHPV) infection. This point-of-care test is usually performed by collecting a cervical specimen in a vial of PreservCyt® transport medium. We compared HPV test positivity and accuracy between self-collected sample with a dry swab (s-DRY) versus physician-collected cervical sampling using a broom like brush and immediate immersion in PreservCyt (dr-WET). METHODS: In this cross-sectional study, we recruited 150 women ≥ 18 years old attending the colposcopy clinic in the University Hospital of Geneva...
2017: PloS One
https://www.readbyqxmd.com/read/28750001/classical-conditioning-without-verbal-suggestions-elicits-placebo-analgesia-and-nocebo-hyperalgesia
#15
Przemysław Bąbel, Elżbieta A Bajcar, Wacław Adamczyk, Paweł Kicman, Natalia Lisińska, Karolina Świder, Luana Colloca
The aim of this study was to examine the relationships among classical conditioning, expectancy, and fear in placebo analgesia and nocebo hyperalgesia. A total of 42 healthy volunteers were randomly assigned to three groups: placebo, nocebo, and control. They received 96 electrical stimuli, preceded by either orange or blue lights. A hidden conditioning procedure, in which participants were not informed about the meaning of coloured lights, was performed in the placebo and nocebo groups. Light of one colour was paired with pain stimuli of moderate intensity (control stimuli), and light of the other colour was paired with either nonpainful stimuli (in the placebo group) or painful stimuli of high intensity (in the nocebo group)...
2017: PloS One
https://www.readbyqxmd.com/read/28749981/a-systematic-review-and-meta-analysis-on-herpes-zoster-and-the-risk-of-cardiac-and-cerebrovascular-events
#16
Nathaniel Erskine, Hoang Tran, Leonard Levin, Christine Ulbricht, Joyce Fingeroth, Catarina Kiefe, Robert J Goldberg, Sonal Singh
BACKGROUND: Patients who develop herpes zoster or herpes zoster ophthalmicus may be at risk for cerebrovascular and cardiac complications. We systematically reviewed the published literature to determine the association between herpes zoster and its subtypes with the occurrence of cerebrovascular and cardiac events. METHODS/RESULTS: Systematic searches of PubMed (MEDLINE), SCOPUS (Embase) and Google Scholar were performed in December 2016. Eligible studies were cohort, case-control, and self-controlled case-series examining the association between herpes zoster or subtypes of herpes zoster with the occurrence of cerebrovascular and cardiac events including stroke, transient ischemic attack, coronary heart disease, and myocardial infarction...
2017: PloS One
https://www.readbyqxmd.com/read/28749970/effectiveness-of-physical-activity-on-patients-with-depression-and-parkinson-s-disease-a-systematic-review
#17
Pei-Ling Wu, Megan Lee, Tzu-Ting Huang
AIM: In this paper we aimed to systematically review the literature on physical activity's effect on depressive symptoms in Parkinson disease. BACKGROUND: Depression is a common symptom of Parkinson's disease and is associated with increased disability, rapid progression of motor symptoms, mortality, and adverse effects on Quality of Life. DESIGN: A systematic review of primary research was undertaken and conducted according to the Preferred Reporting Items for Systematic Reviews...
2017: PloS One
https://www.readbyqxmd.com/read/28749884/original-research-the-effects-of-red-yeast-rice-supplementation-on-cholesterol-levels-in-adults
#18
Diane Peng, Amy Fong, Amanda van Pelt
: Purpose: Red yeast rice (RYR) supplementation has become a popular alternative to statin therapy in treating hypercholesterolemia. This state-of-the-science review seeks to explore the most recent evidence on the effectiveness and safety of RYR supplementation in treating dyslipidemic adults. METHODS: This review extends the time frame of a meta-analysis performed by Li and colleagues in 2014; specifically, we looked at the literature published between September 2013 and April 2016...
August 2017: American Journal of Nursing
https://www.readbyqxmd.com/read/28749830/characteristics-of-patients-involved-in-physical-assault-in-an-acute-inpatient-psychiatric-setting
#19
Sohag N Sanghani, Akeem N Marsh, Majnu John, Arya Soman, Leonardo V Lopez, Yolana A Young, Mark J Russ
BACKGROUND: Although aggressive behavior in psychiatric settings is a major concern, very few studies have focused exclusively on physical assault in a general inpatient psychiatric population. OBJECTIVES: This study had 3 main goals: (1) to evaluate the prevalence of assaultive behavior in an acute psychiatric hospital; (2) to identify the clinical and socio-demographic factors associated with assaultive behavior during hospitalization; and (3) to explore whether a diagnosis of schizophrenia spectrum disorder increases the risk of assaultive behavior...
July 2017: Journal of Psychiatric Practice
https://www.readbyqxmd.com/read/28749764/use-of-serologic-responses-against-enteropathogens-to-assess-the-impact-of-a-point-of-use-water-filter-a-randomized-controlled-trial-in-western-province-rwanda
#20
Laura Divens Zambrano, Jeffrey W Priest, Emil Ivan, John Rusine, Corey Nagel, Miles Kirby, Ghislaine Rosa, Thomas F Clasen
Diarrhea is a leading contributor to childhood morbidity and mortality in sub-Saharan Africa. Given the challenge of blinding most water, sanitation, and hygiene (WASH) interventions, diarrheal disease outcome measures in WASH intervention trials are subject to potential bias and misclassification. Using the platform of a cluster-randomized controlled trial of a household-based drinking water filter in western province, Rwanda, we assessed the impact of the drinking water filter on enteric seroconversion in young children as a health outcome and examined the association between serological responses and caregiver-reported diarrhea...
July 24, 2017: American Journal of Tropical Medicine and Hygiene
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