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https://www.readbyqxmd.com/read/28229080/small-bowel-obstruction-due-to-a-giant-meckel-s-diverticulum
#1
Andreas Minh Luu, Kirsten Meurer, Torsten Herzog, Waldemar Uhl, Andrea Tannapfel, Chris Braumann
BACKGROUND: Meckel's diverticulum is the most common congenital anomaly of the gastrointestinal tract, with an average length of 3 cm. Complications occur in 6.4% and most commonly include inflammation and gastrointestinal bleeding. Preoperative diagnosis is demanding and achieved in 4%. CASE REPORT: A 34-year-old otherwise healthy patient presented with an acute abdomen due to small bowel obstruction. Computed tomography scan could not identify the underlying cause...
December 2016: Visceral Medicine
https://www.readbyqxmd.com/read/28228320/embryo-multinucleation-at-the-two-cell-stage-is-an-independent-predictor-of-intracytoplasmic-sperm-injection-outcomes
#2
Laurent Desch, Céline Bruno, Maxime Luu, Julie Barberet, Cécile Choux, Marjorie Lamotte, Emeline Schmutz, Paul Sagot, Patricia Fauque
OBJECTIVE: To determine the prognostic impact of the nuclear status at the two-cell stage on intracytoplasmic sperm injection (ICSI) outcomes. DESIGN: Retrospective study. SETTING: Hospital. PATIENT(S): Only ICSI cycles with time-lapse monitoring of transferred embryos with known implantation/delivery data from November 2012 to December 2014 were included. A total of 2,449 embryos were assessed for multinucleation rates at the two- and four-cell stage, and 608 transferred embryos were studied for ICSI outcomes...
January 2017: Fertility and Sterility
https://www.readbyqxmd.com/read/28227810/noninvasive-eeg-correlates-of-overground-and-stair-walking
#3
Justin A Brantley, Trieu Phat Luu, Recep Ozdemir, Fangshi Zhu, Anna T Winslow, Helen Huang, Jose L Contreras-Vidal, Justin A Brantley, Trieu Phat Luu, Recep Ozdemir, Fangshi Zhu, Anna T Winslow, Helen Huang, Jose L Contreras-Vidal, Fangshi Zhu, Recep Ozdemir, Justin A Brantley, Helen Huang, Anna T Winslow, Jose L Contreras-Vidal, Trieu Phat Luu
Automated walking intention detection remains a challenge in lower-limb neuroprosthetic systems. Here, we assess the feasibility of extracting motor intent from scalp electroencephalography (EEG). First, we evaluated the corticomuscular coherence between central EEG electrodes (C1, Cz, C2) and muscles of the shank and thigh during walking on level ground and stairs. Second, we trained decoders to predict the linear envelope of the surface electromyogram (EMG). We observed significant EEG-led corticomuscular coupling between electrodes and sEMG (tibialis anterior) in the high delta (3-4 Hz) and low theta (4-5 Hz) frequency bands during level walking, indicating efferent signaling from the cortex to peripheral motor neurons...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28226802/unscented-kalman-filter-for-neural-decoding-of-human-treadmill-walking-from-non-invasive-electroencephalography
#4
Trieu Phat Luu, Yongtian He, Sho Nakagame, Jeffrey Gorges, Kevin Nathan, Jose L Contreras-Vidal, Trieu Phat Luu, Yongtian He, Sho Nakagame, Jeffrey Gorges, Kevin Nathan, Jose L Contreras-Vidal, Jose L Contreras-Vidal, Trieu Phat Luu, Jeffrey Gorges, Yongtian He, Sho Nakagame, Kevin Nathan
The feasibility of decoding lower limb kinematics in human treadmill walking from noninvasive electroencephalography (EEG) has been demonstrated with linear Wiener filter. However, nonlinear relationship between neural activities and limb movements may challenge the linear decoders in real-time brain computer interface (BCI) applications. In this study, we propose a nonlinear neural decoder using an Unscented Kalman Filter (UKF) to infer lower limb joint angles from noninvasive scalp EEG signals during human treadmill walking...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28222165/stress-increases-the-risk-of-type-2-diabetes-onset-in-women-a-12-year-longitudinal-study-using-causal-modelling
#5
Melissa L Harris, Christopher Oldmeadow, Alexis Hure, Judy Luu, Deborah Loxton, John Attia
BACKGROUND: Type 2 diabetes is associated with significant morbidity and mortality. Modifiable risk factors have been found to contribute up to 60% of type 2 diabetes risk. However, type 2 diabetes continues to rise despite implementation of interventions based on traditional risk factors. There is a clear need to identify additional risk factors for chronic disease prevention. The aim of this study was to examine the relationship between perceived stress and type 2 diabetes onset, and partition the estimates into direct and indirect effects...
2017: PloS One
https://www.readbyqxmd.com/read/28208719/micro-computed-tomography-detection-of-gold-nanoparticle-labelled-mesenchymal-stem-cells-in-the-rat-subretinal-layer
#6
Pooi Ling Mok, Sue Ngein Leow, Avin Ee-Hwan Koh, Hairul Harun Mohd Nizam, Suet Lee Shirley Ding, Chi Luu, Raduan Ruhaslizan, Hon Seng Wong, Wan Haslina Wan Abdul Halim, Min Hwei Ng, Ruszymah Binti Hj Idrus, Shiplu Roy Chowdhury, Catherine Mae-Lynn Bastion, Suresh Kumar Subbiah, Akon Higuchi, Abdullah A Alarfaj, Kong Yong Then
Mesenchymal stem cells are widely used in many pre-clinical and clinical settings. Despite advances in molecular technology; the migration and homing activities of these cells in in vivo systems are not well understood. Labelling mesenchymal stem cells with gold nanoparticles has no cytotoxic effect and may offer suitable indications for stem cell tracking. Here, we report a simple protocol to label mesenchymal stem cells using 80 nm gold nanoparticles. Once the cells and particles were incubated together for 24 h, the labelled products were injected into the rat subretinal layer...
February 8, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/28206926/liver-metastases-10-years-after-resection-of-a-benign-insulinoma
#7
Andreas Minh Luu, Torsten Herzog, Waldemar Uhl, Chris Braumann
No abstract text is available yet for this article.
November 1, 2016: American Surgeon
https://www.readbyqxmd.com/read/28205177/measuring-activity-of-cholesterol-synthesis-enzymes-using-gas-chromatography-mass-spectrometry
#8
Anika V Prabhu, Winnie Luu, Andrew J Brown
The development of gas chromatography/mass spectrometry (GC/MS) technology has improved the ease and efficiency with which sterols in biological samples can be analyzed. Its advantages include that it needs only a small amount of sample, a short analysis time, and has enhanced specificity over traditional methods. Furthermore, a major benefit is its nonselective properties, which means that a complete scan of the sample will display the relative abundance of every sterol in the sample. This property has made it possible to define the abnormal, but distinctive, sterol profiles in a number of inborn errors of cholesterol synthesis...
2017: Methods in Molecular Biology
https://www.readbyqxmd.com/read/28205165/manipulating-cholesterol-status-within-cells
#9
Winnie Luu, Ingrid C Gelissen, Andrew J Brown
Cellular cholesterol levels are intricately controlled to maintain homeostasis. Here, we describe ways in which cellular cholesterol status can be manipulated for the study of cholesterol homeostasis, including sterol starvation (by culturing cells in lipoprotein-deficient serum and pretreating/treating with the cholesterol-lowering drug, statin) and sterol enrichment (using cholesterol complexed to cyclodextrin, and low-density lipoprotein). We also describe how to prepare lipoprotein-deficient serum and complex cholesterol to cyclodextrin...
2017: Methods in Molecular Biology
https://www.readbyqxmd.com/read/28196033/thromboembolic-disease-in-patients-with-metastatic-femoral-lesions-a-comparison-between-prophylactic-fixation-and-fracture-fixation
#10
Arun Aneja, Jimmy J Jiang, Anna Cohen-Rosenblum, Hue L Luu, Terrance D Peabody, Samer Attar, T David Luo, Rex C Haydon
BACKGROUND: We are not aware of any previous studies that have compared the rate of venous thromboembolic events in patients who underwent prophylactic intramedullary nailing because of an impending fracture with the rate in patients who underwent intramedullary nailing after a pathological fracture. The objective of the present study was to determine if the rate of venous thromboembolic events varies between patients who are managed with prophylactic fixation and those who are managed with fixation after a pathological fracture...
February 15, 2017: Journal of Bone and Joint Surgery. American Volume
https://www.readbyqxmd.com/read/28192093/the-roles-of-hippocampal-micrornas-in-response-to-acute-postnatal-exposure-to-di-2-ethylhexyl-phthalate-in-female-and-male-rats
#11
Bryan E Luu, Stuart R Green, Christine L Childers, Matthew R Holahan, Kenneth B Storey
Previous studies have shown that di(2-ethylhexyl) phthalate (DEHP) exposure impairs the normal development of pre- and post-synaptic elements of the male, but not female, rat hippocampus. While males seem to be vulnerable to the neurodevelopmental deficits resulting from DEHP exposure, females appear to show a protective response. The purpose of the present study was to characterize hippocampal microRNAs in female and male rats exposed to DEHP to assess whether any patterns emerged that would be consistent with vulnerability in males and resilience in females...
February 10, 2017: Neurotoxicology
https://www.readbyqxmd.com/read/28173617/specificity-of-root-microbiomes-in-native-grown-nicotiana-attenuata-and-plant-responses-to-uvb-increase-deinococcus-colonization
#12
Rakesh Santhanam, Youngjoo Oh, Ramesh Kumar, Arne Weinhold, Van Thi Luu, Karin Groten, Ian T Baldwin
Plants recruit microbial communities from the soil in which they germinate. Our understanding of the recruitment process and the factors affecting it is still limited for most microbial taxa. We analyzed several factors potentially affecting root microbiome structure - the importance of geographic location of natural populations, the microbiome of native seeds as putative source of colonization and the effect of a plant's response to UVB-exposure on root colonization of highly abundant species. The microbiome of Nicotiana attenuata seeds was determined by a culture-dependent and independent approach, and the root microbiome of natural N...
February 7, 2017: Molecular Ecology
https://www.readbyqxmd.com/read/28172520/p3bsseq-parallel-processing-pipeline-software-for-automatic-analysis-of-bisulfite-sequencing-data
#13
Phuc-Loi Luu, Daniela Gerovska, Mikel Arrospide-Elgarresta, Sugoi Retegi-Carrión, Hans R Schöler, Marcos J Araúzo-Bravo
No abstract text is available yet for this article.
February 1, 2017: Bioinformatics
https://www.readbyqxmd.com/read/28170188/endothelial-progenitor-cells-as-prognostic-markers-of-preterm-birth-associated-complications
#14
Mariane Bertagnolli, Anne Monique Nuyt, Bernard Thébaud, Thuy Mai Luu
Preterm birth is associated with alteration of the vascular tree that can result in disease states such as bronchopulmonary dysplasia and retinopathy of prematurity during the neonatal period and emphysema and hypertension in adulthood. Studies have suggested a potential role for endothelial progenitor cells in the pathophysiology of prematurity-related complications involving blood vessels; however, this knowledge has never been synthesized. We conducted a systematic review of the published data to examine the characteristics of endothelial progenitor cells in relation to preterm birth in humans...
January 2017: Stem Cells Translational Medicine
https://www.readbyqxmd.com/read/28159287/adaption-of-an-in-vitro-digestion-method-to-screen-carotenoid-liberation-and-in-vitro-accessibility-from-differently-processed-spinach-preparations
#15
Jane N Eriksen, Amy Y Luu, Lars O Dragsted, Eva Arrigoni
Dark green leafy vegetables are primary food sources for lutein and β-carotene, however these bioactives have low bioavailability. The effects of mechanical and thermal processing as well as fat addition and fat type on lutein and β-carotene liberation and in vitro accessibility from spinach were investigated. Lutein liberation and in vitro accessibility were three-fold higher from spinach puree compared to whole leaves. Results for β-carotene liberation were similar, whereas that of β-carotene accessibility was only about two-fold...
June 1, 2017: Food Chemistry
https://www.readbyqxmd.com/read/28158116/dispersion-characteristics-of-a-suspended-core-optical-fiber-infiltrated-with-water
#16
Khoa Dinh Xuan, Lanh Chu Van, Van Cao Long, Quang Ho Dinh, Luu Van Xuan, Marek Trippenbach, Ryszard Buczynski
In this paper we present a study on the dispersion characteristics in the suspended-core optical fibers made of borosilicate of NC21A glass infiltrated with water. Replacement of air with water results in dramatic improvement of the dispersion characteristics in the fibers, valuable in the process of supercontinuum generation. A near-zero flat dispersion can be achieved in the anomalous or normal dispersion range for various diameters of the core.
February 1, 2017: Applied Optics
https://www.readbyqxmd.com/read/28146322/mechanistic-investigations-of-two-bacterial-diterpene-cyclases-spiroviolene-synthase-and-tsukubadiene-synthase
#17
Patrick Rabe, Jan Rinkel, Etilia Dolja, Thomas Schmitz, Britta Nubbemeyer, T Hoang Luu, Jeroen S Dickschat
The mechanisms of two diterpene cyclases from streptomycetes-one with an unknown product that was identified as the spirocyclic hydrocarbon spiroviolene and one with the known product tsukubadiene-were investigated in detail by isotope labeling experiments. Although the structures of the products were very different, the cyclization mechanisms of both enzymes proceed through the same initial cyclization reactions, before they diverge towards the individual products, which is reflected in the close phylogenetic relationship of the enzymes...
March 1, 2017: Angewandte Chemie
https://www.readbyqxmd.com/read/28133477/early-diagnosis-of-helicobacter-pylori-infection-in-vietnamese-patients-with-acute-peptic-ulcer-bleeding-a-prospective-study
#18
Duc Trong Quach, Mai Ngoc Luu, Toru Hiyama, Thuy-HuongThi To, Quy Nhuan Bui, Tuan Anh Tran, Binh Duy Tran, Minh-Cong Hong Vo, Shinji Tanaka, Naomi Uemura
Aims. To investigate H. pylori infection rate and evaluate a combined set of tests for H. pylori diagnosis in Vietnamese patients with acute peptic ulcer bleeding (PUD). Methods. Consecutive patients with acute PUB were enrolled prospectively. Rapid urease test (RUT) with 3 biopsies was carried out randomly. Patients without RUT or with negative RUT received urea breath test (UBT) and serological and urinary H. pylori antibody tests. H. pylori was considered positive if RUT or any noninvasive test was positive...
2017: Gastroenterology Research and Practice
https://www.readbyqxmd.com/read/28132162/population-pharmacokinetics-and-pharmacodynamics-of-ionis-gcgrrx-an-antisense-oligonucleotide-for-type-2-diabetes-mellitus-a-red-blood-cell-lifespan-model
#19
Kenneth T Luu, Erin S Morgan, Sanjay Bhanot, Richard Geary, Anne Smith, Claudette Bethune, Lynnetta Watts, Scott Henry, Yanfeng Wang
IONIS-GCGRRx (ISIS 449884) is an antisense oligonucleotide inhibitor of the glucagon receptor (GCGR). The objective of this study was to evaluate the pharmacokinetics (PK) and pharmacodynamics (PD) of IONIS-GCGRRx via population-based modeling. The observed data were obtained from a Phase 1 (50, 100, 200, 300 and 400 mg) single- and multiple-dose study in healthy volunteers and a Phase 2 (100 and 200 mg) multiple-dose study in T2DM patients. The PK of IONIS GCGRRx was characterized by two primary systemic compartments and three absorption transit compartments with elimination out of the peripheral compartment...
January 28, 2017: Journal of Pharmacokinetics and Pharmacodynamics
https://www.readbyqxmd.com/read/28130498/myeloid-atg16l1-facilitates-host-bacteria-interactions-in-maintaining-intestinal-homeostasis
#20
Hong Zhang, Libo Zheng, Dermot P B McGovern, Ariel M Hamill, Ryan Ichikawa, Yoshitake Kanazawa, Justin Luu, Kotaro Kumagai, Marianne Cilluffo, Masayuki Fukata, Stephan R Targan, David M Underhill, Xiaolan Zhang, David Q Shih
Intact ATG16L1 plays an essential role in Paneth cell function and intestinal homeostasis. However, the functional consequences of ATG16L1 deficiency in myeloid cells, particularly macrophages, are not fully characterized. We generated mice with Atg16l1 deficiency in myeloid and dendritic cells and showed that mice with myeloid Atg16l1 deficiency had exacerbated colitis in two acute and one chronic model of colitis with increased proinflammatory to anti-inflammatory macrophage ratios, production of proinflammatory cytokines, and numbers of IgA-coated intestinal microbes...
March 1, 2017: Journal of Immunology: Official Journal of the American Association of Immunologists
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