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https://www.readbyqxmd.com/read/28211060/shifting-gears-an-inpatient-medical-record-audit-and-post-discharge-survey-of-return-to-driving-following-stroke-transient-ischaemic-attack
#1
Janet Frith, Helen Warren-Forward, Isobel Hubbard, Carole James
BACKGROUND/AIM: In Australia, all stroke survivors should not drive for four weeks and transient ischaemic attack (TIA) survivors should not drive for two weeks. This study investigates the provision of return-to-driving education in the acute hospital setting and the use of this education by a cohort of Australian patients who have experienced a mild stroke or TIA and who are discharged directly home from their acute hospital admission. METHODS: A medical record audit was conducted of stroke patients discharged home from a regional hospital in Australia...
February 16, 2017: Australian Occupational Therapy Journal
https://www.readbyqxmd.com/read/28202868/rt-pa-with-antithrombotic-therapies-in-a-case-with-capsular-warning-syndrome
#2
Yasuhiro Fuseya, Miyuki Kawamura, Eri Matsuda, Kozue Takada, Kiwamu Watanabe, Junko Fujitake, Yoshifumi Nakaya
We herein report a case of capsular warning syndrome (CWS) that was successfully treated with recombinant tissue plasminogen activator (rt-PA). A 70-year-old woman had repeated stereotyped transient ischemic attacks (TIAs) of right hemiparesis and dysarthria. After hospitalization, argatroban, aspirin, and cilostazol were started but were ineffective. Thirteen hours after the first episode of TIAs, severe symptoms occurred. Magnetic resonance imaging showed acute infarctions in the internal capsule to corona radiata, so we used rt-PA...
2017: Internal Medicine
https://www.readbyqxmd.com/read/28202699/association-of-multiple-infarctions-and-icas-with-outcomes-of-minor-stroke-and-tia
#3
Yuesong Pan, Xia Meng, Jing Jing, Hao Li, Xingquan Zhao, Liping Liu, David Wang, S Claiborne Johnston, Yilong Wang, Yongjun Wang
OBJECTIVE: To estimate the association of different patterns of infarction and intracranial arterial stenosis (ICAS) with the prognosis of acute minor ischemic stroke and TIA. METHODS: We derived data from the Clopidogrel in High-risk Patients with Acute Nondisabling Cerebrovascular Events (CHANCE) trial. A total of 1,089 patients from 45 of 114 participating sites of the trial undergoing baseline MRI/angiography were included in this subgroup analysis. Patterns of infarction and ICAS were recorded for each individual...
February 15, 2017: Neurology
https://www.readbyqxmd.com/read/28199997/specificities-of-ischemic-stroke-risk-factors-in-arab-speaking-countries
#4
Halim Abboud, Leila Sissani, Julien Labreuche, Antonio Arauz, Marie-Germaine Bousser, Alain Bryer, Angel Chamorro, Marc Fisher, Ian Ford, Kim M Fox, Michael G Hennerici, Pablo M Lavados, Ayrton Massaro, Heinrich P Mattle, Mario Munoz Collazos, Peter M Rothwell, Philippe Gabriel Steg, Eric Vicaut, Bassem Yamouth, Pierre Amarenco
BACKGROUND: Stroke is largely preventable, and therefore, a better understanding of risk factors is an essential step in reducing the population stroke rate and resulting disease burden in Arab countries. SUMMARY: We performed 2 separate analyses in 2 similar populations of patients with noncardioembolic ischemic stroke. This first involved 3,635 patients in the Outcomes in Patients with TIA and Cerebrovascular disease (OPTIC) registry (followed for 2 years), with baseline collection of the usual risk factors and 5 socioeconomic variables (unemployment status, residence in rural area, living in fully serviced accommodation, no health-insurance coverage, and low educational level)...
February 15, 2017: Cerebrovascular Diseases
https://www.readbyqxmd.com/read/28196949/referral-pathways-for-patients-with-tia-avoiding-hospital-admission-a-scoping-review
#5
Bridie Angela Evans, Khalid Ali, Jenna Bulger, Gary A Ford, Matthew Jones, Chris Moore, Alison Porter, Alan David Pryce, Tom Quinn, Anne C Seagrove, Helen Snooks, Shirley Whitman, Nigel Rees
OBJECTIVE: To identify the features and effects of a pathway for emergency assessment and referral of patients with suspected transient ischaemic attack (TIA) in order to avoid admission to hospital. DESIGN: Scoping review. DATA SOURCES: PubMed, CINAHL Web of Science, Scopus. STUDY SELECTION: Reports of primary research on referral of patients with suspected TIA directly to specialist outpatient services. DATA EXTRACTION: We screened studies for eligibility and extracted data from relevant studies...
February 14, 2017: BMJ Open
https://www.readbyqxmd.com/read/28196817/comparison-of-carotid-plaque-score-and-coronary-artery-calcium-score-for-predicting-cardiovascular-disease-events-the-multi-ethnic-study-of-atherosclerosis
#6
Adam D Gepner, Rebekah Young, Joseph A Delaney, Matthew J Budoff, Joseph F Polak, Michael J Blaha, Wendy S Post, Erin D Michos, Joel Kaufman, James H Stein
BACKGROUND: Coronary artery calcium (CAC) predicts coronary heart disease (CHD) events better than carotid wall plaque presence; however, differences in the utility of CAC burden and carotid plaque burden across the spectrum of cardiovascular disease (CVD) events is unknown. METHODS AND RESULTS: CVD, CHD and stroke/transient ischemic attack (TIA) events were evaluated prospectively in a multiethnic cohort without CVD at baseline. Carotid plaque score was determined by the number of ultrasound-detected plaques in the common, bifurcation, and internal carotid artery segments...
February 14, 2017: Journal of the American Heart Association
https://www.readbyqxmd.com/read/28193996/a-case-report-of-primary-nasal-natural-killer-nk-t-cell-lymphoma-in-an-african-american-patient-presenting-with-hemophagocytic-syndrome
#7
Bowei Tan, Cherif Abdelmalek, James E O'Donnell, Thomas Toltaku, Rashid Chaudhry, Jen C Wang, Vladimir Gotlieb
BACKGROUND Extranodal natural killer/T-cell lymphoma, nasal type (ENKTCL) is generally an aggressive and rare non-Hodgkin lymphoma. It is most common in East Asians, Native Americans, and South Americans, but is rarely reported in blacks. CASE REPORT A 55-year-old African American male born in Grenada presented with a left nostril mass with facial swelling and biopsy subsequently confirmed a diagnosis of extranodal NK/T-cell lymphoma, nasal type (ENKTCL). Immunochemistry was positive for CD2, cytoplasmic CD3, CD7, CD 43, CD 56, granzyme B, and TIA-1...
February 14, 2017: American Journal of Case Reports
https://www.readbyqxmd.com/read/28192589/a-critical-evaluation-of-refractive-outcomes-following-lasik-for-moderate-to-high-astigmatism-using-two-excimer-laser-platforms
#8
Sudi Patel, Maja Bohac, Alma Biscevic, Mateja Koncarevic, Marija Anticic, Nikica Gabric
PURPOSE: To calculate the surgically induced astigmatism (SIA) following LASIK and identify any association between SIA and the target induced astigmatism (TIA) at 1 year postoperatively. METHODS: The SIA was calculated using the TIA and residual astigmatism values for [A] myopic astigmatism and [B] mixed astigmatism treated with either the [I] WaveLight Allegretto EyeQ 400-Hz (Alcon Laboratories, Inc. Fort Worth, TX) or [II] Schwind Amaris 750S (Schwind eye-tech-solutions, Kleinostheim, Germany) platforms...
February 1, 2017: Journal of Refractive Surgery
https://www.readbyqxmd.com/read/28192264/balloon-angioplasty-for-in-stent-restenosis-resulting-in-carotid-stent-fracture-with-literature-review-of-stent-in-stent-technique-as-a-viable-therapeutic-option
#9
Abdul-Haseeb Naeem, Ghaya Al-Rumaihi, Amirpouyan Namavarian, Manas Sharma, Melfort Boulton
BACKGROUND: Carotid stent fractures are rare and multiple etiologies have been proposed to explain their occurrence. We present a patient with a internal carotid artery (ICA) stent who developed in-stent restenosis. We performed balloon angioplasty to address in-stent restenosis but post-procedure he developed a carotid stent fracture. To our knowledge, balloon angioplasty has not been reported to cause stent fractures and we report the first case report. CASE DESCRIPTION: 72-year-old male underwent stenting for symptomatic left ICA stenosis with post-stenting residual stenosis of 55%...
February 9, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28191906/intracardiac-echocardiography-for-verification-for-left-atrial-appendage-thrombus-presence-detected-by-transesophageal-echocardiography-the-actionice-ii-study
#10
Jakub Baran, Beata Zaborska, Roman Piotrowski, Malgorzata Sikora-Frąc, Ewa Pilichowska-Paszkiet, Piotr Kułakowski
BACKGROUND: Transesophageal echocardiography (TEE) remains the gold standard for exclusion of left atrial appendage (LAA) thrombus in patients scheduled for direct electrical cardioversion (DEC) or atrial fibrillation (AF) ablation. Recently, intracardiac echocardiography (ICE) of the pulmonary artery (PA) has been shown to provide excellent LAA images and to be useful in verification of equivocal TEE findings. HYPOTHESIS: ICE of the PA may have a role in detecting false-positive TEE results...
February 13, 2017: Clinical Cardiology
https://www.readbyqxmd.com/read/28191697/composite-lymphoma-of-peripheral-t-cell-lymphoma-and-hodgkin-lymphoma-mixed-cellularity-type-pathological-and-molecular-analysis
#11
Ayako Ichikawa, Hiroaki Miyoshi, Takuji Yamauchi, Fumiko Arakawa, Riko Kawano, Hiroko Muta, Yasuo Sugita, Koichi Akashi, Koichi Ohshima
Composite lymphomas (CLs) are defined as two unrelated lymphomas occurring at the same time within the same tissue. The incidence of these tumors is low. Of all possible combinations between lymphomas, the least frequent are the ones combining peripheral T-cell lymphoma (PTCL) and Hodgkin lymphoma (HL). We recently identified five cases of CL composed of PTCL and classical HL, mixed cellularity type. We investigated histological and clinical features of these cases. Immunostaining was performed on paraffin sections...
February 13, 2017: Pathology International
https://www.readbyqxmd.com/read/28190951/allostatic-load-as-a-complex-clinical-construct-a-case-based-computational-modeling-approach
#12
J Galen Buckwalter, Brian Castellani, Bruce McEwen, Arun S Karlamangla, Albert A Rizzo, Bruce John, Kyle O'Donnell, Teresa Seeman
Allostatic load (AL) is a complex clinical construct, providing a unique window into the cumulative impact of stress. However, due to its inherent complexity, AL presents two major measurement challenges to conventional statistical modeling (the field's dominant methodology): it is comprised of a complex causal network of bioallostatic systems, represented by an even larger set of dynamic biomarkers; and, it is situated within a web of antecedent socioecological systems, linking AL to differences in health outcomes and disparities...
September 2016: Complexity
https://www.readbyqxmd.com/read/28190714/carotid-endarterectomy-should-not-be-based-on-consensus-statement-duplex-velocity-criteria
#13
Jesse A Columbo, Bjoern D Suckow, Claire L Griffin, Jack L Cronenwett, Philip P Goodney, Timothy G Lukovits, Robert M Zwolak, Mark F Fillinger
OBJECTIVE: Randomized trials support carotid endarterectomy (CEA) in asymptomatic patients with ≥60% internal carotid artery (ICA) stenosis. The widely referenced Society for Radiologists in Ultrasound Consensus Statement on carotid duplex ultrasound (CDUS) imaging indicates that an ICA peak systolic velocity (PSV) ≥230 cm/s corresponds to a ≥70% ICA stenosis, leading to the potential conclusion that asymptomatic patients with an ICA PSV ≥230 cm/s would benefit from CEA. Our goal was to determine the natural history stroke risk of asymptomatic patients who might have undergone CEA based on consensus statement PSV of ≥230 cm/s but instead were treated medically based on more conservative CDUS imaging criteria...
February 9, 2017: Journal of Vascular Surgery
https://www.readbyqxmd.com/read/28186939/cardiac-diagnostic-work-up-for-atrial-fibrillation-after-transient-ischaemic-attacks-in-england-and-wales-results-from-a-cross-sectional-survey
#14
Olivia Geraghty, Eleni Korompoki, Filippos T Filippidis, Anthony Rudd, Roland Veltkamp
OBJECTIVES: Transient ischaemic attacks (TIAs) are an important precursor of stroke. Atrial fibrillation (AF) is among the most dangerous aetiologies shared between TIAs and strokes. Detection of AF after TIAs is essential for the initiation of oral anticoagulants. We aimed to identify variations in the use of cardiac investigations used to detect AF and cardiac pathology in patients with TIA in the UK. SETTING: All TIA clinical leads in England and Wales received an invitation by email to participate in an online survey in February 2015...
November 10, 2016: BMJ Open
https://www.readbyqxmd.com/read/28186720/cuprizone-intoxication-induces-cell-intrinsic-alterations-in-oligodendrocyte-metabolism-independent-of-copper-chelation
#15
Alexandra Taraboletti, Tia Louise Walker, Robin Avila, He Huang, Joel Caporoso, Erendra Manandhar, Thomas C Leeper, David A Modarelli, Satish Medicetty, Leah P Shriver
Cuprizone intoxication is a common animal model used to test myelin regenerative therapies to treat diseases such as multiple sclerosis. Mice fed this copper chelator develop reversible, region-specific oligodendrocyte loss and demyelination. While the cellular changes influencing the demyelinating process have been explored in this model, there is no consensus on the biochemical mechanisms of toxicity in oligodendrocytes and if this damage arises from the chelation of copper in vivo. Here we have identified an oligodendroglial cell line that displays sensitivity to cuprizone toxicity and performed global metabolomic profiling to determine biochemical pathways altered by this treatment...
February 10, 2017: Biochemistry
https://www.readbyqxmd.com/read/28184449/tia-1-rrm23-binding-and-recognition-of-target-oligonucleotides
#16
Saboora Waris, Sofía M García-Mauriño, Andrew Sivakumaran, Simone A Beckham, Fionna E Loughlin, Myriam Gorospe, Irene Díaz-Moreno, Matthew C J Wilce, Jacqueline A Wilce
No abstract text is available yet for this article.
February 10, 2017: Nucleic Acids Research
https://www.readbyqxmd.com/read/28180991/mri-to-measure-cervical-sagittal-parameters-a-comparison-with-plain-radiographs
#17
Rong Xing, Guofeng Zhou, Qian Chen, Yun Liang, Jian Dong
INTRODUCTION: The inability to visualize the sternum tip and T1 vertebra on radiographs may decrease the accuracy of the measurements of cervical sagittal parameters. The object of this study is to investigate the value of MRI to measure cervical sagittal parameters and to compare the data of cervical sagittal parameters on radiographs and MR images. MATERIALS AND METHODS: Fifty-two asymptomatic adults were recruited. Each subject had both an MRI and radiographs of the cervical spine...
February 8, 2017: Archives of Orthopaedic and Trauma Surgery
https://www.readbyqxmd.com/read/28179050/cerebral-amyloid-angiopathy-in-stroke-medicine
#18
Frank Block, Manuel Dafotakis
BACKGROUND: Cerebral amyloid angiopathy (CAA) is a degenerative vasculopathy that is classically associated with lobar intracerebral or sulcal hemorrhage. Its prevalence is estimated at 30% in the seventh decade and 50% in the eighth and ninth decades. In this review, we summarize the risks linked to CAA with respect to the treatment and prevention of stroke. METHODS: This review is based on pertinent publications retrieved by a selective search employing the terms "amyloid cerebral angiopathy," "stroke," "intra - cerebral bleeding," and "acute stroke therapy...
January 20, 2017: Deutsches Ärzteblatt International
https://www.readbyqxmd.com/read/28178407/predictive-factors-for-good-outcome-and-mortality-after-stent-retriever-thrombectomy-in-patients-with-acute-anterior-circulation-stroke
#19
Woong Yoon, Seul Kee Kim, Man Seok Park, Byung Hyun Baek, Yun Young Lee
BACKGROUND AND PURPOSE: Predictive factors associated with stent-retriever thrombectomy for patients with acute anterior circulation stroke remain to be elucidated. This study aimed to investigate clinical and procedural factors predictive of good outcome and mortality after stent-retriever thrombectomy in a large cohort of patients with acute anterior circulation stroke. METHODS: We analyzed clinical and procedural data in 335 patients with acute anterior circulation stroke treated with stent-retriever thrombectomy...
January 2017: Journal of Stroke
https://www.readbyqxmd.com/read/28176500/role-of-perfusion-weighted-imaging-in-a-diffusion-weighted-imaging-negative-transient-ischemic-attack
#20
Sang Hun Lee, Hyun Wook Nah, Bum Joon Kim, Sung Ho Ahn, Jong S Kim, Dong Wha Kang, Sun U Kwon
BACKGROUND AND PURPOSE: The absence of acute ischemic lesions in diffusion-weighted imaging (DWI) in transient ischemic attack (TIA) patients makes it difficult to diagnose the true vascular etiologies. Among patients with DWI-negative TIA, we investigated whether the presence of a perfusion-weighted imaging (PWI) abnormality implied a true vascular event by identifying new acute ischemic lesions in follow-up magnetic resonance imaging (MRI) in areas corresponding to the initial PWI abnormality...
January 12, 2017: Journal of Clinical Neurology
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