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Arterial pulse transit time

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https://www.readbyqxmd.com/read/28269566/dual-modality-arterial-pulse-monitoring-system-for-continuous-blood-pressure-measurement
#1
Wen-Xuan Dai, Yuan-Ting Zhang, Jing Liu, Xiao-Rong Ding, Ni Zhao
Accurate and ambulatory measurement of blood pressure (BP) is essential for efficient diagnosis, management and prevention of cardiovascular diseases (CVDs). However, traditional cuff-based BP measurement methods provide only intermittent BP readings and can cause discomfort with the occlusive cuff. Although pulse transit time (PTT) method is promising for cuffless and continuous BP measurement, its pervasive use is restricted by its limited accuracy and requirement of placing sensors on multiple body sites...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28269221/cuff-pressure-induced-pat-changes-modelling-and-experimental-verification-towards-calibration-of-blood-pressure-surrogates
#2
Erik Bresch, Lars Schmitt, Dennis De Matteis, Jens Muehlsteff
Arterial Blood Pressure (ABP) is one of the most often measured vital parameters in daily clinical practice. State-of-the-Art non-invasive ABP measurement technologies have obvious limitations and are still mainly based on uncomfortable techniques by complete or partial occlusions of arteries. Additionally, embodiments are bulky, difficult to apply for the layman, or provide only intermittent measurements. We have been investigating the pulse arrival time (PAT) and pulse transit time (PTT) methodology for unobtrusive blood pressure (BP) measurements...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28269220/using-multiple-placements-of-accelerometers-to-measure-cardiovascular-pulse-transit-times
#3
Natalie Kurgan Canino, Ruisheng Wang, Charles J Robinson
To measure pulse transit times (PTT) and calculate pulse wave velocities (PWV), tri-axial and uniaxial accelerometers were placed in groups of 2 to 4 over the manubrium, xiphoid process, forehead, wrist and ankle, and/or over the carotid, femoral, and posterior auricular arteries in 11 consented supine subjects. Signals were sampled at 1 kHz and filtered. Radial vectors were calculated from the tri-axial measurements. A 3-lead ECG was simultaneously collected over the same 180 s window, as well as respiratory rate...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227821/dual-modality-arterial-pulse-monitoring-system-for-continuous-blood-pressure-measurement
#4
Wen-Xuan Dai, Yuan-Ting Zhang, Jing Liu, Xiao-Rong Ding, Ni Zhao, Wen-Xuan Dai, Yuan-Ting Zhang, Jing Liu, Xiao-Rong Ding, Ni Zhao, Wen-Xuan Dai, Yuan-Ting Zhang, Xiao-Rong Ding, Ni Zhao, Jing Liu
Accurate and ambulatory measurement of blood pressure (BP) is essential for efficient diagnosis, management and prevention of cardiovascular diseases (CVDs). However, traditional cuff-based BP measurement methods provide only intermittent BP readings and can cause discomfort with the occlusive cuff. Although pulse transit time (PTT) method is promising for cuffless and continuous BP measurement, its pervasive use is restricted by its limited accuracy and requirement of placing sensors on multiple body sites...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227451/cuff-pressure-induced-pat-changes-modelling-and-experimental-verification-towards-calibration-of-blood-pressure-surrogates
#5
Erik Bresch, Lars Schmitt, Dennis De Matteis, Jens Muehlsteff, Erik Bresch, Lars Schmitt, Dennis De Matteis, Jens Muehlsteff, Erik Bresch, Dennis De Matteis, Lars Schmitt, Jens Muehlsteff
Arterial Blood Pressure (ABP) is one of the most often measured vital parameters in daily clinical practice. State-of-the-Art non-invasive ABP measurement technologies have obvious limitations and are still mainly based on uncomfortable techniques by complete or partial occlusions of arteries. Additionally, embodiments are bulky, difficult to apply for the layman, or provide only intermittent measurements. We have been investigating the pulse arrival time (PAT) and pulse transit time (PTT) methodology for unobtrusive blood pressure (BP) measurements...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227450/using-multiple-placements-of-accelerometers-to-measure-cardiovascular-pulse-transit-times
#6
Natalie Kurgan Canino, Ruisheng Rick Wang, Charles J Robinson, Natalie Kurgan Canino, Ruisheng Wang, Charles J Robinson, Natalie Kurgan Canino, Charles J Robinson, Ruisheng Rick Wang
To measure pulse transit times (PTT) and calculate pulse wave velocities (PWV), tri-axial and uniaxial accelerometers were placed in groups of 2 to 4 over the manubrium, xiphoid process, forehead, wrist and ankle, and/or over the carotid, femoral, and posterior auricular arteries in 11 consented supine subjects. Signals were sampled at 1 kHz and filtered. Radial vectors were calculated from the tri-axial measurements. A 3-lead ECG was simultaneously collected over the same 180 s window, as well as respiratory rate...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28220077/noninvasive-assessment-of-the-effect-of-position-and-exercise-on-pulse-arrival-to-peripheral-vascular-beds-in-healthy-volunteers
#7
Yurie Obata, Qi J Ong, J T Magruder, Helen Grichkevitch, Dan E Berkowitz, Daniel Nyhan, Jochen Steppan, Viachaslau Barodka
Background: The effects of position and exercise on pulse wave distribution across a healthy, compliant arterial tree are not fully understood. We studied the effects of exercise and position on the pattern of pulse arrival times (PATs) in healthy volunteers. Moreover, we compared the pulse arrival time ratios to the respective distance ratios between different locations. Methods: Thirteen young healthy volunteers were studied, using an electrocardiogram and plethysmograph to simultaneously record pulse wave arrival at the ear lobe, index finger and big toe...
2017: Frontiers in Physiology
https://www.readbyqxmd.com/read/28207773/local-versus-global-aortic-pulse-wave-velocity-in-early-atherosclerosis-an-animal-study-in-apoe-mice-using-ultrahigh-field-mri
#8
Alexander Gotschy, Wolfgang R Bauer, Patrick Winter, Peter Nordbeck, Eberhard Rommel, Peter M Jakob, Volker Herold
Increased aortic stiffness is known to be associated with atherosclerosis and has a predictive value for cardiovascular events. This study aims to investigate the local distribution of early arterial stiffening due to initial atherosclerotic lesions. Therefore, global and local pulse wave velocity (PWV) were measured in ApoE-/- and wild type (WT) mice using ultrahigh field MRI. For quantification of global aortic stiffness, a new multi-point transit-time (TT) method was implemented and validated to determine the global PWV in the murine aorta...
2017: PloS One
https://www.readbyqxmd.com/read/28179195/multiplexed-mri-methods-for-rapid-estimation-of-global-cerebral-metabolic-rate-of-oxygen-consumption
#9
Hyunyeol Lee, Michael C Langham, Ana E Rodriguez-Soto, Felix W Wehrli
The global cerebral metabolic rate of oxygen (CMRO2), which reflects metabolic activity of the brain under various physiologic conditions, can be quantified using a method, referred to as 'OxFlow', which simultaneously measures hemoglobin oxygen saturation in a draining vein (Yv) and total cerebral blood flow (tCBF). Conventional OxFlow (Conv-OxFlow) entails four interleaves incorporated in a single pulse sequence - two for phase-contrast based measurement of tCBF in the supplying arteries of the neck, and two to measure the intra- to extravascular phase difference in the superior sagittal sinus to derive Yv [Jain et al...
February 6, 2017: NeuroImage
https://www.readbyqxmd.com/read/28159487/the-use-of-pulse-transit-time-in-pediatric-sleep-studies-a-systematic-review
#10
REVIEW
Laurelle A Smith, Patrick J Dawes, Barbara C Galland
As a surrogate measure of blood pressure, pulse transit time (PTT) is commonly used in studies investigating arterial function and respiratory sleep disturbance. A systematic search of the literature was conducted with the aim of reviewing the usefulness of the technique within pediatric sleep studies. All studies that used PTT as a diagnostic tool during sleep in infants, children or adolescents were considered. The search yielded 425 articles, of which 21 full-text articles met inclusion criteria, the majority reporting on obstructive sleep apnea (OSA)...
November 30, 2016: Sleep Medicine Reviews
https://www.readbyqxmd.com/read/28113300/estimation-of-pulse-transit-time-as-a-function-of-blood-pressure-using-a-nonlinear-arterial-tube-load-model
#11
Mingwu Gao, Hao-Min Cheng, Shih-Hsien Sung, Chen-Huan Chen, Nicholas B Olivier, Ramakrishna Mukkamala
OBJECTIVE: Pulse transit time (PTT) varies with blood pressure (BP) throughout the cardiac cycle, yet, because of wave reflection, only one PTT value at the diastolic BP level is conventionally estimated from proximal and distal BP waveforms. The objective was to establish a technique to estimate multiple PTT values at different BP levels in the cardiac cycle. METHODS: A technique was developed for estimating PTT as a function of BP (to indicate the PTT value for every BP level) from proximal and distal BP waveforms...
September 22, 2016: IEEE Transactions on Bio-medical Engineering
https://www.readbyqxmd.com/read/28102355/determining-arterial-wave-transit-time-from-a-single-aortic-pressure-pulse-in-rats-vascular-impulse-response-analysis
#12
Ru-Wen Chang, Chun-Yi Chang, Liang-Chuan Lai, Ming-Shiou Wu, Tai-Horng Young, Yih-Sharng Chen, Chih-Hsien Wang, Kuo-Chu Chang
Arterial wave transit time (τw) in the lower body circulation is an effective biomarker of cardiovascular risk that substantially affects systolic workload imposed on the heart. This study evaluated a method for determining τw from the vascular impulse response on the basis of the measured aortic pressure and an assumed triangular flow (Q(tri)). The base of the unknown Q(tri) was constructed with a duration set equal to ejection time. The timing of the peak triangle was derived using a fourth-order derivative of the pressure waveform...
January 19, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28090301/pulmonary-pulse-wave-transit-time-is-associated-with-right-ventricular-pulmonary-artery-coupling-in-pulmonary-arterial-hypertension
#13
Kurt W Prins, E Kenneth Weir, Stephen L Archer, Jeremy Markowitz, Lauren Rose, Marc Pritzker, Richard Madlon-Kay, Thenappan Thenappan
Pulmonary pulse wave transit time (pPTT), defined as the time for the systolic pressure pulse wave to travel from the pulmonary valve to the pulmonary veins, has been reported to be reduced in pulmonary arterial hypertension (PAH); however, the underlying mechanism of reduced pPTT is unknown. Here, we investigate the hypothesis that abbreviated pPTT in PAH results from impaired right ventricular-pulmonary artery (RV-PA) coupling. We quantified pPTT using pulsed-wave Doppler ultrasound from 10 healthy age- and sex-matched controls and 36 patients with PAH...
December 2016: Pulmonary Circulation
https://www.readbyqxmd.com/read/28060961/pilot-study-estimation-of-stroke-volume-and-cardiac-output-from-pulse-wave-velocity
#14
Yurie Obata, Maki Mizogami, Daniel Nyhan, Dan E Berkowitz, Jochen Steppan, Viachaslau Barodka
BACKGROUND: Transesophageal echocardiography (TEE) is increasingly replacing thermodilution pulmonary artery catheters to assess hemodynamics in patients at high risk for cardiovascular morbidity. However, one of the drawbacks of TEE compared to pulmonary artery catheters is the inability to measure real time stroke volume (SV) and cardiac output (CO) continuously. The aim of the present proof of concept study was to validate a novel method of SV estimation, based on pulse wave velocity (PWV) in patients undergoing cardiac surgery...
2017: PloS One
https://www.readbyqxmd.com/read/28046980/we-fg-206-05-new-arterial-spin-labeling-method-for-simultaneous-estimation-of-arterial-cerebral-blood-volume-cerebral-blood-flow-and-arterial-transit-time
#15
M Johnston, H Liu, C Whitlow, Y Jung
PURPOSE: To demonstrate the feasibility of a novel Arterial Spin Labeling (ASL) method for simultaneously measuring cerebral blood flow (CBF), arterial transit time (ATT), and arterial cerebral blood volume (aCBV) without the use of a contrast agent. METHODS: A series of multi-TI ASL images were acquired from one healthy subject on a 3T Siemens Skyra, with the following parameters: PCASL labeling with variable TI [300, 400, 500, 600, 700, 800, 900, 1000, 1500, 2000, 2500, 3000, 3500, 4000] ms, labeling bolus 1400 ms when TI allows, otherwise 100 ms less than TI, TR was minimized for each TI, two sinc shaped pre-saturation pulses were applied in the imaging plane immediately before 2D EPI acquisition...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/27976741/weighing-scale-based-pulse-transit-time-is-a-superior-marker-of-blood-pressure-than-conventional-pulse-arrival-time
#16
Stephanie L-O Martin, Andrew M Carek, Chang-Sei Kim, Hazar Ashouri, Omer T Inan, Jin-Oh Hahn, Ramakrishna Mukkamala
Pulse transit time (PTT) is being widely pursued for cuff-less blood pressure (BP) monitoring. Most efforts have employed the time delay between ECG and finger photoplethysmography (PPG) waveforms as a convenient surrogate of PTT. However, these conventional pulse arrival time (PAT) measurements include the pre-ejection period (PEP) and the time delay through small, muscular arteries and may thus be an unreliable marker of BP. We assessed a bathroom weighing scale-like system for convenient measurement of ballistocardiography and foot PPG waveforms - and thus PTT through larger, more elastic arteries - in terms of its ability to improve tracking of BP in individual subjects...
December 15, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27923785/genetic-determination-of-the-vascular-reactions-in-humans-in-response-to-the-diving-reflex
#17
Tatiana I Baranova, Dmitrii N Berlov, Oleg S Glotov, Ekaterina A Korf, Alexey D Minigalin, Alla V Mitrofanova, Ildus I Ahmetov, Andrey S Glotov
The purpose of this study was to investigate the genetic mechanisms of the defense vascular reactions in response to the diving reflex in humans with polymorphisms in the genes ADBR2, ACE, AGTR1, BDKRB2, and REN We hypothesized that protective vascular reactions, in response to the diving reflex, are genetically determined and are distinguished in humans with gene polymorphisms of the renin-angiotensin and kinin-bradykinin system. A total of 80 subjects (19 ± 1.4 yr) participated in the study. The intensity of the vascular response was estimated using photoplethysmogram...
March 1, 2017: American Journal of Physiology. Heart and Circulatory Physiology
https://www.readbyqxmd.com/read/27900333/the-effects-of-hemodynamic-changes-on-pulse-wave-velocity-in-cardiothoracic-surgical-patients
#18
Yurie Obata, Maki Mizogami, Sarabdeep Singh, Daniel Nyhan, Dan E Berkowitz, Jochen Steppan, Viachaslau Barodka
The effect of blood pressure on pulse wave velocity (PWV) is well established. However, PWV variability with acute hemodynamic changes has not been examined in the clinical setting. The aim of the present study is to investigate the effect of hemodynamic changes on PWV in patients who undergo cardiothoracic surgery. Using data from 25 patients, we determined blood pressure (BP), heart rate (HR), and the left ventricular outflow tract (LVOT) velocity-time integral. By superimposing the radial arterial waveform on the continuous wave Doppler waveform of the LVOT, obtained by transesophageal echo, we were able to determine pulse transit time and to calculate PWV, stroke volume (SV), cardiac output (CO), and systemic vascular resistance (SVR)...
2016: BioMed Research International
https://www.readbyqxmd.com/read/27867733/multi-wavelength-photoplethysmography-method-for-skin-arterial-pulse-extraction
#19
Jing Liu, Bryan Ping-Yen Yan, Wen-Xuan Dai, Xiao-Rong Ding, Yuan-Ting Zhang, Ni Zhao
In this work, we present a multi-wavelength (MW) PPG method exploiting the wavelength dependence of light penetration in skin tissue to provide depth resolution of skin blood pulsation. The MW PPG system requires two to three light sources in different wavelengths and extracts the arterial blood pulsation through a multi-wavelength multi-layer light-skin interaction model, which removes the capillary pulsation (determined from the short-wavelength PPG signal) from the long-wavelength PPG signal using absorption weighting factors that are quasi-analytically calibrated...
October 1, 2016: Biomedical Optics Express
https://www.readbyqxmd.com/read/27843548/assessment-of-proximal-pulmonary-arterial-stiffness-using-magnetic-resonance-imaging-effects-of-technique-age-and-exercise
#20
Jonathan R Weir-McCall, Anu Kamalasanan, Deidre B Cassidy, Allan D Struthers, Brian J Lipworth, J Graeme Houston
INTRODUCTION: To compare the reproducibility of pulmonary pulse wave velocity (PWV) techniques, and the effects of age and exercise on these. METHODS: 10 young healthy volunteers (YHV) and 20 older healthy volunteers (OHV) with no cardiac or lung condition were recruited. High temporal resolution phase contrast sequences were performed through the main pulmonary arteries (MPAs), right pulmonary arteries (RPAs) and left pulmonary arteries (LPAs), while high spatial resolution sequences were obtained through the MPA...
2016: BMJ Open Respiratory Research
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