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https://www.readbyqxmd.com/read/28449455/the-many-facets-of-diagnostic-bronchoscopy-for-pulmonary-ground-glass-nodules
#1
EDITORIAL
Christine Chavez, Takehiro Izumo
No abstract text is available yet for this article.
March 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/28434846/effect-of-an-automated-tracking-registry-on-the-rate-of-tracking-failure-in-incidental-pulmonary-nodules
#2
Jonathan Shelver, Chris H Wendt, Melissa McClure, Brian Bell, Angela E Fabbrini, Thomas Rector, Kathryn Rice
OBJECTIVE: Following incidental lung nodules with interval CT scanning is an accepted method to detect early lung cancer, but delayed tracking or failure to track is reported in up to 40% of patients. METHODS: Our institution developed and implemented an automated lung nodule registry tracking system. This system uses a code at the time that a suspicious nodule is discovered to populate the registry. Suspicious nodules were defined as any nodule, solid or ground glass, <3 cm that the radiologist recorded as a potential malignancy or recommended for follow-up imaging...
April 20, 2017: Journal of the American College of Radiology: JACR
https://www.readbyqxmd.com/read/28429379/retrospective-evaluation-of-thoracic-computed-tomography-findings-in-dogs-naturally-infected-by-angiostrongylus-vasorum
#3
Mark E Coia, Gawain Hammond, Daniel Chan, Randi Drees, David Walker, Kevin Murtagh, Janine Stone, Nicholas Bexfield, Lizzie Reeve, Jenny Helm
Angiostrongylus vasorum (A. vasorum) is an important emerging disease of canidae. Cardiorespiratory signs are common in affected dogs, therefore thoracic imaging is critical for diagnosing and monitoring disease. Descriptions of thoracic computed tomography (CT) findings in dogs naturally infected with A. vasorum are currently lacking. Aims of this multicenter, retrospective study were to describe thoracic CT findings in a group of dogs with confirmed disease, determine whether any changes were consistent among dogs, and propose standardized terms for describing thoracic CT findings...
April 20, 2017: Veterinary Radiology & Ultrasound
https://www.readbyqxmd.com/read/28429205/comparison-of-digital-tomosynthesis-and-computed-tomography-for-lung-nodule-detection-in-sos-screening-program
#4
Maurizio Grosso, Roberto Priotto, Donatella Ghirardo, Alberto Talenti, Emanuele Roberto, Luca Bertolaccini, Alberto Terzi, Stéphane Chauvie
PURPOSE: To compare the lung nodules' detection of digital tomosynthesis (DTS) and computed tomography (CT) in the context of the SOS (Studio OSservazionale) prospective screening program for lung cancer detection. MATERIALS AND METHODS: One hundred and thirty-two of the 1843 subjects enrolled in the SOS study underwent CT because non-calcified nodules with diameters larger than 5 mm and/or multiple nodules were present in DTS. Two expert radiologists reviewed the exams classifying the nodules based on their radiological appearance and their dimension...
April 20, 2017: La Radiologia Medica
https://www.readbyqxmd.com/read/28423576/solitary-ground-glass-opacity-nodules-of-stage-ia-pulmonary-adenocarcinoma-combination-of-18f-fdg-pet-ct-and-high-resolution-computed-tomography-features-to-predict-invasive-adenocarcinoma
#5
Jun Zhou, Yanli Li, Yiqiu Zhang, Guobing Liu, Hui Tan, Yan Hu, Jie Xiao, Hongcheng Shi
To investigate the performance of combined 18F-FDG Positron Emission Tomography/Computed Tomography with high-resolution CT for differentiating invasive adenocarcinoma from adenocarcinoma in situ (pre-invasive lesion) or minimally invasive adenocarcinoma in stage IA lung cancer patients with solitary ground-glass opacity nodules. This retrospective study enrolled 58 consecutive stage IA pulmonary adenocarcinoma patients with solitary ground-glass opacity nodules. The characteristics and measurements of the ground-glass opacity nodules as pure ground-glass opacity nodules and mixed ground-glass opacity nodules in the pre-invasive or minimally invasive adenocarcinoma and invasive adenocarcinoma groups on Positron Emission Tomography/Computed Tomography and high-resolution CT were compared and analyzed...
April 4, 2017: Oncotarget
https://www.readbyqxmd.com/read/28422852/stage-i-lung-adenocarcinoma-the-value-of-quantitative-ct-in-differentiating-pathological-subtypes-and-predicting-growth-of-subsolid-nodules
#6
Xianqun Xu, Kaisong Wu, Yanyan Zhao, Liejun Mei
The aim of this study was to investigate feasibility of quantitative computed tomography (CT) measurements in predicting invasiveness and growth of nodular ground glass opacities (nGGOs).A set of 203 patients (group A) with nGGOs that were confirmed stage-I adenocarcinomas and 79 patients (group B) with nGGOs that were completely followed up were included. Lesions diameters, volume (VOL), maximum (MAX), mean (MEN), and standard deviation (STD) of CT attenuation were measured. P53 labeling index (LI) was evaluated through immunohistochemistry in group-A patients...
April 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28413146/-multiple-ground-glass-opacities-nodules
#7
D Moreau, V Gazaille, N Allou, C Fernandez, V André, M André
INTRODUCTION: Ground-glass opacities nodules are frequently detected with the advances of radiological imaging. These can be preinvasive lesions such as atypical adenomatous hyperplasia but also invasive lesions. It leads to question in patients with lung cancer about treatment strategy and follow up. CASE REPORT: We report the case of a 72 years-old woman followed for a lung adenocarcinoma with an EGFR mutation of the right upper lobe stage IIb. The CT scan shows multiple pure ground-glass opacities in the same lobe of the primitive tumor but also in the other lobe...
April 13, 2017: Revue de Pneumologie Clinique
https://www.readbyqxmd.com/read/28386719/ct-and-histopathologic-characteristics-of-lung-adenocarcinoma-with-pure-ground-glass-nodules-10-mm-or-less-in-diameter
#8
Fang Wu, Shu-Ping Tian, Xin Jin, Rui Jing, Yue-Qing Yang, Mei Jin, Shao-Hong Zhao
OBJECTIVE: To evaluate CT and histopathologic features of lung adenocarcinoma with pure ground-glass nodule (pGGN) ≤10 mm in diameter. METHODS: CT appearances of 148 patients (150 lesions) who underwent curative resection of lung adenocarcinoma with pGGN ≤10 mm (25 atypical adenomatous hyperplasias, 42 adenocarcinoma in situs, 38 minimally invasive adenocarcinomas, and 45 invasive pulmonary adenocarcinomas) were analyzed for lesion size, density, bubble-like sign, air bronchogram, vessel changes, margin, and tumour-lung interface...
April 6, 2017: European Radiology
https://www.readbyqxmd.com/read/28386717/co-registration-of-pre-operative-ct-with-ex-vivo-surgically-excised-ground-glass-nodules-to-define-spatial-extent-of-invasive-adenocarcinoma-on-in-vivo-imaging-a-proof-of-concept-study
#9
Mirabela Rusu, Prabhakar Rajiah, Robert Gilkeson, Michael Yang, Christopher Donatelli, Rajat Thawani, Frank J Jacono, Philip Linden, Anant Madabhushi
OBJECTIVE: To develop an approach for radiology-pathology fusion of ex vivo histology of surgically excised pulmonary nodules with pre-operative CT, to radiologically map spatial extent of the invasive adenocarcinomatous component of the nodule. METHODS: Six subjects (age: 75 ± 11 years) with pre-operative CT and surgically excised ground-glass nodules (size: 22.5 ± 5.1 mm) with a significant invasive adenocarcinomatous component (>5 mm) were included...
April 6, 2017: European Radiology
https://www.readbyqxmd.com/read/28384959/thoracic-sarcoidosis-imaging-with-high-resolution-computed-tomography
#10
Peeyush Kumar Dhagat, Sarvinder Singh, Megha Jain, Satyendra Narayan Singh, Rajat Kumar Sharma
INTRODUCTION: Sarcoidosis is a disease of unknown aetiology that primarily affects the lungs. Clinical and radiological findings with demonstration of non caseating granulomas on pathology is utilised for diagnosing the disease. AIM: To assess and evaluate the features of thoracic sarcoidosis on High Resolution Computed Tomography (HRCT) chest. MATERIALS AND METHODS: A total of 40 (31 males and 9 females) cases of pulmonary sarcoidosis in a period of three years were included in this study...
February 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28362556/bronchiolitis-a-practical-approach-for-the-general-radiologist
#11
Peter J Winningham, Santiago Martínez-Jiménez, Melissa L Rosado-de-Christenson, Sonia L Betancourt, Carlos S Restrepo, Andrés Eraso
Radiologists consciously or unconsciously encounter bronchiolitis on images frequently. The purpose of this article is to simplify the concept of bronchiolitis to facilitate the formulation of a succinct and accurate differential diagnosis and suggest potential causes for the imaging findings. Direct and indirect signs of bronchiolitis that are seen on computed tomographic images are detailed. The most common causes of bronchiolitis are covered, including several distinct entities to be considered in specific clinical scenarios...
March 31, 2017: Radiographics: a Review Publication of the Radiological Society of North America, Inc
https://www.readbyqxmd.com/read/28338535/lung-cancers-associated-with-cystic-airspaces-natural-history-pathologic-correlation-and-mutational-analysis
#12
Florian J Fintelmann, Jesaja K Brinkmann, William R Jeck, Fabian M Troschel, Subba R Digumarthy, Mari Mino-Kenudson, Jo-Anne O Shepard
PURPOSE: The aim of the study was to investigate the natural history of non-small cell lung cancers (NSCLCs) associated with cystic airspaces, including histopathology and molecular analysis. MATERIALS AND METHODS: A total of 34,801 computed tomographic (CT) scans of 2954 patients diagnosed with NSCLC between 2010 and 2015 were evaluated for association with a cystic airspace. Characteristics on serial CT, 18F-fludeoxyglucose positron emission tomography, and pathologic analysis were recorded...
May 2017: Journal of Thoracic Imaging
https://www.readbyqxmd.com/read/28331820/correlation-in-histological-subtypes-with-high-resolution-computed-tomography-signatures-of-early-stage-lung-adenocarcinoma
#13
Yingying Miao, Jianya Zhang, Jiawei Zou, Qingqing Zhu, Tangfeng Lv, Yong Song
BACKGROUND: Uncertainty remains on the association between image characteristics of the nodules in computed tomography (CT) scans and lung adenocarcinoma histopathologic subtypes. We aimed to estimate the correlation between preoperative high resolution computed tomography (HRCT) scan and postoperative histopathology of stage IA lung adenocarcinoma in East Asian Chinese population. METHODS: We retrospectively reviewed the clinical records and HRCT images of 190 patients (106 female and 84 male) with resected, preoperatively untreated stage IA adenocarcinomas...
February 2017: Translational Lung Cancer Research
https://www.readbyqxmd.com/read/28328859/single-stage-nonintubated-uniportal-thoracoscopic-resection-of-synchronous-bilateral-pulmonary-nodules-after-coil-labeling-a-case-report-and-literature-review
#14
Miao Zhang, Tao Wang, You-Wei Zhang, Wen-Bin Wu, Heng Wang, Rong-Hua Xu
RATIONALE: Preoperative localization of small pulmonary nodules is essential for precise resection, besides, the optimal treatment for pulmonary nodules is controversial and the prognosis without surgery is uncertain. PATIENT CONCERNS: Herein we present a patient with compromised pulmonary function harboring synchronous triple ground-glass nodules located separately in different pulmonary lobes. DIAGNOSES: The pathological diagnosis of the nodules were chronic inflammation, inflammatory pseudotumor and atypical adenomatous hyperplasia, respectively...
March 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28321808/uncommon-features-of-surgically-resected-alk-positive-cavitary-lung-adenocarcinoma-a-case-report
#15
Shinkichi Takamori, Masafumi Yamaguchi, Kenichi Taguchi, Makoto Edagawa, Shinichiro Shimamatsu, Ryo Toyozawa, Kaname Nosaki, Fumihiko Hirai, Takashi Seto, Mitsuhiro Takenoyama, Yukito Ichinose
Some features found on chest computed tomography (CT), such as central tumor location, large pleural effusion, and the absence of a pleural tail, and a patient age of less than 60 years, have been suggested to be useful in predicting anaplastic lymphoma kinase (ALK) rearrangement in patients with non-small cell lung cancer (NSCLC).A 68-year-old female patient with a history of gynecological treatment was found to have a cavitary mass in the right lower lobe on an annual chest roentgenogram. The tumor was located in the peripheral area with a pleural tail showing no pleural effusion...
December 2017: Surgical Case Reports
https://www.readbyqxmd.com/read/28321331/ct-patterns-of-organizing-pneumonia-in-patients-treated-with-vegf-mtor-inhibitors-for-metastatic-renal-cell-cancer-an-observational-study
#16
Sabine Dettmer, Viktor Grünwald, Thomas Fuehner, Arnold Ganser, Frank Wacker, Philipp Ivanyi, Thomas Rodt
BACKGROUND: Targeted therapies are the standard treatment in patients with metastatic renal cell carcinoma (mRCC) and are known to cause adverse pulmonary events. Organizing pneumonia (OP) with its various manifestations in computed tomography (CT) has therefore lately received more attention. PURPOSE: To describe the spectrum of CT patterns of OP in patients with mRCC receiving targeted therapies. MATERIAL AND METHODS: Seventeen patients with known therapy-related OP were analyzed retrospectively by two blinded radiologists in consensus...
February 2017: Acta Radiologica Open
https://www.readbyqxmd.com/read/28314525/intraoperative-electromagnetic-navigational-bronchoscopic-localization-of-small-deep-or-subsolid-pulmonary-nodules
#17
Abbas Abbas, Sagar Kadakia, Vishnu Ambur, Kimberly Muro, Larry Kaiser
BACKGROUND: Localizing small or deep pulmonary nodules or subsolid ground-glass opacities often is difficult during video-assisted thoracoscopic surgery (VATS) or robotic-assisted thoracoscopic surgery (RATS). This can result in larger resections or conversion to thoracotomy. The goal of this study is to evaluate the role of electromagnetic navigational bronchoscopic localization (ENBL) as a safe and accurate intraoperative method to localize small, deep, or subsolid nodules. METHODS: This is a single-institution, single-surgeon retrospective study of all patients (51) who underwent combined ENBL and resection of 54 nodules between May 2013 and August 2015...
February 7, 2017: Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/28297814/-igg4-related-lung-disease-analysis-of-8-cases-and-literature-review
#18
G J Han, H Hu, D Mao, X Bai, D Y She, S F Zhao, Z L Wen, J Gao
Objective: To improve the understanding and treatment of IgG4-related lung disease (IgG4-RLD). Methods: The clinical characteristics, serum IgG4 levels, pathological features, chest CT, therapy and prognosis of 8 patients with IgG4-RLD were retrospectively analyzed. These patients were admitted to the People's Liberation Army General Hospital and the pathological diagnosis was made between December 2005 and March 2016. Relevant literatures were reviewed. Results: The 8 patients with IgG4-RLD included 4 men and 4 women, with an average age of (59±4) years (range, 37-74)...
March 12, 2017: Chinese Journal of Tuberculosis and Respiratory Diseases
https://www.readbyqxmd.com/read/28296757/radiological-prediction-of-tumor-invasiveness-of-lung-adenocarcinoma-on-thin-section-ct
#19
Masahiro Yanagawa, Takeshi Johkoh, Masayuki Noguchi, Eiichi Morii, Yasushi Shintani, Meinoshin Okumura, Akinori Hata, Maki Fujiwara, Osamu Honda, Noriyuki Tomiyama
To evaluate thin-section computed tomography (CT) (TSCT) features that differentiate adenocarcinoma in situ (AIS), minimally invasive adenocarcinoma (MIA), and invasive adenocarcinoma (IVA), and to determine the size of solid portion on CT that correlates to pathological invasive components. Forty-eight patients were included. Nodules were classified into ground-glass nodule (GGN), part-solid, solid, and heterogeneous. Visual density of GGNs was subjectively evaluated using reference standard images: faint GGN (Ga), <-700 Hounsfield unit (HU); intermediate GGN (Gb), from -700 to -400 HU; dense GGN (Gc), >-400 HU; and mixed (Ga + Gb, Ga + Gc, and Gb + Gc)...
March 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28285338/a-study-of-computer-aided-diagnosis-for-pulmonary-nodule-comparison-between-classification-accuracies-using-calculated-image-features-and-imaging-findings-annotated-by-radiologists
#20
Masami Kawagishi, Bin Chen, Daisuke Furukawa, Hiroyuki Sekiguchi, Koji Sakai, Takeshi Kubo, Masahiro Yakami, Koji Fujimoto, Ryo Sakamoto, Yutaka Emoto, Gakuto Aoyama, Yoshio Iizuka, Keita Nakagomi, Hiroyuki Yamamoto, Kaori Togashi
PURPOSE: In our previous study, we developed a computer-aided diagnosis (CADx) system using imaging findings annotated by radiologists. The system, however, requires radiologists to input many imaging findings. In order to reduce such an interaction of radiologists, we further developed a CADx system using derived imaging findings based on calculated image features, in which the system only requires few user operations. The purpose of this study is to check whether calculated image features (CFT) or derived imaging findings (DFD) can represent information in imaging findings annotated by radiologists (AFD)...
March 11, 2017: International Journal of Computer Assisted Radiology and Surgery
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