keyword
MENU ▼
Read by QxMD icon Read
search

cognitive reserve

keyword
https://www.readbyqxmd.com/read/28529871/subtle-alterations-in-cerebrovascular-reactivity-in-mild-cognitive-impairment-detected-by-graph-theoretical-analysis-and-not-by-the-standard-approach
#1
Carlos A Sánchez-Catasús, Gretel Sanabria-Diaz, Antoon Willemsen, Eduardo Martinez-Montes, Juan Samper-Noa, Angel Aguila-Ruiz, Ronald Boellaard, Peter De Deyn, Rudi A J O Dierckx, Lester Melie-Garcia
There is growing support that cerebrovascular reactivity (CVR) in response to a vasodilatory challenge, also defined as the cerebrovascular reserve, is reduced in Alzheimer's disease dementia. However, this is less clear in patients with mild cognitive impairment (MCI). The current standard analysis may not reflect subtle abnormalities in CVR. In this study, we aimed to investigate vasodilatory-induced changes in the topology of the cerebral blood flow correlation (CBFcorr) network to study possible network-related CVR abnormalities in MCI...
2017: NeuroImage: Clinical
https://www.readbyqxmd.com/read/28527230/imaging-and-neuropsychological-correlates-of-white-matter-lesions-in-different-subtypes-of-mild-cognitive-impairment-a-systematic-review
#2
Charlene L M Lam, Jenny Yiend, Tatia M C Lee
BACKGROUND: White matter lesions (WML) are prevalent in older adults. The association between WML and cognition in different subtypes of Mild Cognitive Impairment (MCI) is inconsistent in the literature. OBJECTVES: We aim to provide a systematic review on the impact of WML in different subtypes of MCI, and discuss the recent findings on white matter plasticity. METHODS: We reviewed peer-reviewed articles from January 2011 to August 2016 and identified 12 studies investigating the association between WML and subtypes of MCI with both neuroimaging and cognitive measures...
May 13, 2017: NeuroRehabilitation
https://www.readbyqxmd.com/read/28527220/quantitative-erythrocyte-omega-3-epa-plus-dha-levels-are-related-to-higher-regional-cerebral-blood-flow-on-brain-spect
#3
Daniel G Amen, William S Harris, Parris M Kidd, Somayeh Meysami, Cyrus A Raji
BACKGROUND: The interrelationships between omega-3 fatty acids status, brain perfusion, and cognition are not well understood. OBJECTIVE: To evaluate if SPECT brain imaging of cerebral perfusion and cognition varies as a function of omega-3 fatty acid levels. METHODS: A random sample of 166 study participants was drawn from a psychiatric referral clinical for which erythrocyte quantification of omega-3 eicosapentaenoic acid (EPA) plus docosahexaenoic acid (DHA) (the Omega-3 Index) was available...
May 18, 2017: Journal of Alzheimer's Disease: JAD
https://www.readbyqxmd.com/read/28526147/pharmacologic-considerations-of-anesthetic-agents-in-geriatric-patients
#4
REVIEW
Maunak V Rana, Lara K Bonasera, Gregory J Bordelon
Aging is a natural process of declining organ function and reserve. Census data show that the geriatric population is expected to grow to nearly 30%. More than half of geriatric patients have 1 or more surgical procedures in their lifetimes. Moreover, this is the population at greatest risk of morbidity and mortality with any given complication. There is remarkable variability in health across the age spectrum, from fit to frail and compromised. This variability requires a unique approach to anesthetic delivery and drug dosing on an individual basis to avoid complications such as postoperative cognitive dysfunction and delirium...
June 2017: Anesthesiology Clinics
https://www.readbyqxmd.com/read/28521844/cognitive-reserve-as-a-moderator-of-the-negative-association-between-mood-and-cognition-evidence-from-a-population-representative-cohort
#5
C Opdebeeck, F E Matthews, Y-T Wu, R T Woods, C Brayne, L Clare
BACKGROUND: Cognitive reserve (CR) has been associated with better cognitive function and lower risk of depression in older people, yet it remains unclear whether CR moderates the association between mood and cognition. This study aimed to investigate whether a comprehensive indicator of CR, including education, occupation and engagement in cognitive and social activities, acts as a moderator of this association. METHODS: This was a cross-sectional study utilising baseline data from the Cognitive Function and Ageing Study II (CFAS II), a large population-based cohort of people aged 65+ in England...
May 19, 2017: Psychological Medicine
https://www.readbyqxmd.com/read/28520675/the-role-of-cognitive-reserve-in-recovery-from-traumatic-brain-injury
#6
Kayla A Steward, Richard Kennedy, Thomas A Novack, Michael Crowe, Daniel C Marson, Kristen L Triebel
OBJECTIVE: To examine whether cognitive reserve (CR) attenuates the initial impact of traumatic brain injury (TBI) on cognitive performance (neural reserve) and results in faster cognitive recovery rates in the first year postinjury (neural compensation), and whether the advantage of CR differs on the basis of the severity of TBI. SETTING: Inpatient/outpatient clinics at an academic medical center. PARTICIPANTS: Adults with mild TBI (mTBI; n = 28), complicated mild TBI (cmTBI; n = 24), and moderate to severe TBI (msevTBI; n = 57), and demographically matched controls (n = 66)...
May 17, 2017: Journal of Head Trauma Rehabilitation
https://www.readbyqxmd.com/read/28513102/how-bilingualism-protects-the-brain-from-aging-insights-from-bimodal-bilinguals
#7
Le Li, Jubin Abutalebi, Karen Emmorey, Gaolang Gong, Xin Yan, Xiaoxia Feng, Lijuan Zou, Guosheng Ding
Bilingual experience can delay cognitive decline during aging. A general hypothesis is that the executive control system of bilinguals faces an increased load due to controlling two languages, and this increased load results in a more "tuned brain" that eventually creates a neural reserve. Here we explored whether such a neuroprotective effect is independent of language modality, i.e., not limited to bilinguals who speak two languages but also occurs for bilinguals who use a spoken and a signed language. We addressed this issue by comparing bimodal bilinguals to monolinguals in order to detect age-induced structural brain changes and to determine whether we can detect the same beneficial effects on brain structure, in terms of preservation of gray matter volume (GMV), for bimodal bilinguals as has been reported for unimodal bilinguals...
May 17, 2017: Human Brain Mapping
https://www.readbyqxmd.com/read/28511173/is-occupational-complexity-associated-with-cognitive-performance-or-decline-results-from-the-australian-longitudinal-study-of-ageing
#8
Anna P Lane, Tim D Windsor, Ross Andel, Mary A Luszcz
BACKGROUND: Long-term protective associations proposed between previous complex occupational tasks and cognitive functioning in later life point to work roles contributing to cognitive reserve. OBJECTIVE: To examine occupational complexity involving data, people, and things in relation to the level of, and rate of change in, cognitive functioning. METHODS: Participants were 1,290 members of the Australian Longitudinal Study of Ageing and initially aged 65-102 years (mean = 79)...
May 17, 2017: Gerontology
https://www.readbyqxmd.com/read/28509415/ratings-of-affective-and-interpersonal-tendencies-differ-for-grandiose-and-vulnerable-narcissism-a-replication-and-extension-of-gore-widiger
#9
Courtland S Hyatt, Chelsea E Sleep, Donald R Lynam, Thomas A Widiger, W Keith Campbell, Joshua D Miller
OBJECTIVE: Theoretical conceptions of narcissism have long been characterized by two seemingly opposing poles: grandiosity and vulnerability. The goal of the current study was to investigate the extent to which traits associated with one profile are perceived to co-occur with the other within an individual. METHOD: Lay raters (n = 862; 56% female; 80% Caucasian; mean age = 37) recruited from Amazon's MTurk and assigned to one of four conditions in which they rated how often a series of narcissistic traits were displayed by a prototypical grandiose narcissist, vulnerable narcissist, a close friend, or themselves...
May 16, 2017: Journal of Personality
https://www.readbyqxmd.com/read/28506658/-cognitive-neuroscience-of-aging-explanatory-models
#10
Fabrissio Grandi, Javier Tirapu Ustárroz
The aim of the cognitive neuroscience of aging is the study of brain activity and the cognitive processes associated with age. In order to understand the dynamics of neurocognitive activity in older people, the present review highlights four explanatory models. The first one (HAROLD) highlights brain bilaterality, mainly in the pre-frontal cortex. The second paradigm (PASA) places special emphasis on neuronal polarisation (anterior-posterior). The third model (CRUNCH) relates the manifest activity of the brain to the level of complexity of the task...
May 12, 2017: Revista Española de Geriatría y Gerontología
https://www.readbyqxmd.com/read/28502406/steering-the-conversation-a-linguistic-exploration-of-natural-language-interactions-with-a-digital-assistant-during-simulated-driving
#11
David R Large, Leigh Clark, Annie Quandt, Gary Burnett, Lee Skrypchuk
Given the proliferation of 'intelligent' and 'socially-aware' digital assistants embodying everyday mobile technology - and the undeniable logic that utilising voice-activated controls and interfaces in cars reduces the visual and manual distraction of interacting with in-vehicle devices - it appears inevitable that next generation vehicles will be embodied by digital assistants and utilise spoken language as a method of interaction. From a design perspective, defining the language and interaction style that a digital driving assistant should adopt is contingent on the role that they play within the social fabric and context in which they are situated...
September 2017: Applied Ergonomics
https://www.readbyqxmd.com/read/28500766/melatonin-inhibits-neuronal-dysfunction-associated-with-neuroinflammation-by-atopic-psychological-stress-in-nc-nga-atopic-like-mouse-models
#12
Gunhyuk Park, Seung Hoon Lee, Dal-Seok Oh, Yong-Ung Kim
Atopic dermatitis (AD), also known as atopic eczema, is chronic pruritic skin disease. AD can increase psychological stress as well, increasing glucocorticoid release and exacerbating the associated symptoms. Chronic glucocorticoid elevation disturbs neuroendocrine signaling, and can induce neuroinflammation, neurotoxicity, and cognitive impairment; however, it is unclear if AD-related psychological stress elevates glucocorticoids enough to cause neuronal damage. Therefore, we assessed the effects of AD-induced stress in a mouse AD model...
May 13, 2017: Journal of Pineal Research
https://www.readbyqxmd.com/read/28500650/aberrant-cognitive-phenotypes-and-altered-hippocampal-bdnf-expression-related-to-epigenetic-modifications-in-mice-lacking-the-post-synaptic-scaffolding-protein-shank1-implications-for-autism-spectrum-disorder
#13
A Özge Sungur, Magdalena C E Jochner, Hani Harb, Ayşe Kılıç, Holger Garn, Rainer K W Schwarting, Markus Wöhr
Autism spectrum disorder (ASD) is a class of neurodevelopmental disorders characterized by persistent deficits in social communication/interaction, together with restricted/repetitive patterns of behavior. ASD is among the most heritable neuropsychiatric conditions, and while available evidence points to a complex set of genetic factors, the SHANK gene family has emerged as one of the most promising candidates. Here, we assessed ASD-related phenotypes with particular emphasis on social behavior and cognition in Shank1 mouse mutants in comparison to heterozygous and wildtype littermate controls across development in both sexes...
May 12, 2017: Hippocampus
https://www.readbyqxmd.com/read/28498615/understanding-the-impact-of-haemodialysis-on-uk-nhs-patients-wellbeing-a-qualitative-investigation
#14
Daniel J W Jones, Kate Harvey, John P Harris, Laurie T Butler, Emma C Vaux
AIMS AND OBJECTIVES: While haemodialysis (HD) is an effective treatment for end-stage renal disease (ESRD), the requirements and restrictions it imposes on patients can be onerous. The aim of the current study was to obtain UK National Health Service (NHS) patients' perspectives on the challenges arising from HD with the intention of identifying potential improvements. BACKGROUND: Depression rates are particularly high in those with ESRD, however, there is limited insight into the range of stressors associated with HD treatment within the NHS contributing to such high rates, particularly those of a cognitive or psychological nature...
May 12, 2017: Journal of Clinical Nursing
https://www.readbyqxmd.com/read/28494105/empathy-in-pediatric-intensive-care-nurses-part-2-neural-correlates
#15
Philip L Jackson, Margot Latimer, Fanny Eugène, Emily Macleod, Tara Hatfield, Etienne Vachon-Presseau, Pierre-Emmanuel Michon, Kenneth M Prkachin
AIMS: To determine if there are brain activity differences between pediatric intensive care nurses and allied health professionals during pain intensity rating tasks and test whether these differences are related to the population observed (infant or adult) and professional experience. BACKGROUND: The underestimation of patients' pain by healthcare professionals has generally been associated with patterns of change in neural response to vicarious pain, notably reduced activation in regions associated with affective sharing and increased activation in regions associated with regulation, compared with controls...
May 11, 2017: Journal of Advanced Nursing
https://www.readbyqxmd.com/read/28493647/the-liminality-of-the-patient-with-dementia-in-geriatric-rehabilitation-hospitals
#16
Robin Digby, Susan Lee, Allison Williams
AIM: The aim was to explore the experiences of people with dementia in sub-acute geriatric rehabilitation hospitals to critically evaluate the care received by such patients. BACKGROUND: Globally the number of people with dementia is growing and is expected to impact progressively more on health systems. People with dementia can become deconditioned and deteriorate in cognitive function while in hospital. The unfamiliar environment and people can cause the person to become disorientated which then leads to behavioural symptoms which complicate care...
May 11, 2017: Journal of Clinical Nursing
https://www.readbyqxmd.com/read/28493624/the-effect-of-acute-exercise-on-blood-concentrations-of-brain-derived-neurotrophic-factor-bdnf-in-healthy-adults-a-meta-analysis
#17
REVIEW
Adam Dinoff, Nathan Herrmann, Walter Swardfager, Krista L Lanctôt
It has been hypothesized that one mechanism through which physical activity provides benefits to cognition and mood is via increasing brain-derived neurotrophic factor (BDNF) concentrations. Some studies have reported immediate benefits to mood and various cognitive domains after a single session of exercise. This meta-analysis sought to determine the effect of a single exercise session on concentrations of BDNF in peripheral blood, in order to evaluate the potential role of BDNF in mediating the beneficial effects of exercise on brain health...
May 11, 2017: European Journal of Neuroscience
https://www.readbyqxmd.com/read/28490858/social-network-size-and-cognitive-functioning-in-middle-aged-adults-cross-sectional-and-longitudinal-associations
#18
Daniel Eriksson Sörman, Michael Rönnlund, Anna Sundström, Margareta Norberg, Lars-Göran Nilsson
The objective of the present study was to examine relations between social network size and three cognitive abilities (episodic memory, semantic memory, visuospatial ability) in middle-aged adults. We analyzed cross-sectional data on social network size and cognitive functioning that were available for 804 participants aged 40-60 years. In addition, we examined 5- and 10-year follow-up measurements of cognitive functioning that were available for 604 and 255 participants, respectively. Cross-sectional analyses revealed a positive association between social network size and each of the three cognitive abilities...
2017: Journal of Adult Development
https://www.readbyqxmd.com/read/28489322/developmental-effects-of-androgens-in-the-human-brain
#19
REVIEW
Tuong-Vi Nguyen
Neuroendocrine theories of brain development posit that androgens play a crucial role in sex-specific cortical growth, but little is known about the differential effects of testosterone and dehydroepiandrosterone (DHEA) on cortico-limbic development and cognition during adolescence. In this context, the NIH Study of Normal Brain Development, a longitudinal study of typically developing children and adolescents 4 to 24 years of age (n=433), offered a unique opportunity to examine the developmental effects of androgens on cortico-limbic maturation and cognition...
May 10, 2017: Journal of Neuroendocrinology
https://www.readbyqxmd.com/read/28489317/pharmacogenomics-of-angiotensin-receptor-neprilysin-inhibitor-and-its-long-term-side-effects
#20
REVIEW
Chayakrit Krittanawong, Takeshi Kitai
The development of the promising agent sacubitril/valsartan, known as an angiotensin receptor blocker-neprilysin inhibitor (ARNI), to improve heart failure (HF) management, may benefit morbidity, mortality, and readmission rates in patients with HF. The PARADIGM-HF trial demonstrated that the ARNI can reduce morbidity and mortality in patients with heart failure with reduced ejection fraction (HFrEF), while ongoing PARAMOUNT and PARAGON-HF trials determined whether the ARNI has morbidity and mortality benefits in patients with heart failure with preserved ejection fraction (HFpEF)...
May 10, 2017: Cardiovascular Therapeutics
keyword
keyword
38613
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"