Daniel J Taylor, Harry Saxton, Ian Halliday, Tom Newman, Jeroen Feher, Rebecca Gosling, Andrew J Narracott, Denise van Kemenade, Marcel Van't Veer, Pim A L Tonino, Michel Rochette, D Rodney Hose, Julian P Gunn, Paul D Morris
BACKGROUND: Myocardial ischaemia results from insufficient coronary blood flow. Computed virtual fractional flow reserve (vFFR) allows quantification of proportional flow loss without the need for invasive pressure-wire testing. In the current study, we describe a novel, conductivity model of side branch flow, referred to as 'leak'. This leak model is a function of taper and local pressure, the latter of which may change radically when focal disease is present. This builds upon previous techniques, which either ignore side branch flow, or rely purely on anatomical factors...
March 18, 2024: Computers in Biology and Medicine