keyword
https://read.qxmd.com/read/38529330/corrigendum-regional-myocardial-work-measured-by-echocardiography-for-the-detection-of-myocardial-ischemic-segments-a-comparative-study-with-invasive-fractional-flow-reserve
#1
Ying Guo, Chenguang Yang, Xiang Wang, Zuowei Pei, Huolan Zhu, Xuyang Meng, Ziyu Zhou, Xiaotong Lang, Sun Ning, Ruisheng Zhang, Fang Wang
[This corrects the article DOI: 10.3389/fcvm.2022.813710.].
2024: Frontiers in Cardiovascular Medicine
https://read.qxmd.com/read/38526753/diagnostic-accuracy-of-murray-law-based-quantitative-flow-ratio-in-patients-with-severe-aortic-stenosis-undergoing-transcatheter-aortic-valve-replacement
#2
JOURNAL ARTICLE
Fukuishi Yuta, Hiroyuki Kawamori, Takayoshi Toba, Takashi Hiromasa, Satoru Sasaki, Tomoyo Hamana, Hiroyuki Fujii, Yuto Osumi, Seigo Iwane, Tetsuya Yamamoto, Shota Naniwa, Yuki Sakamoto, Koshi Matsuhama, Ken-Ichi Hirata, Hiromasa Otake
BACKGROUND: Murray law-based quantitative flow ratio (μQFR) is a novel computational method that enables accurate estimation of fractional flow reserve (FFR) using a single angiographic projection. However, its diagnostic value in patients with severe aortic stenosis (AS) remains unclear. METHOD: We included 25 consecutive patients who underwent transcatheter aortic valve replacement (TAVR) for severe AS with intermediate or greater (30-90%) coronary artery disease (CAD)...
March 25, 2024: Heart and Vessels
https://read.qxmd.com/read/38525948/high-resolution-free-breathing-automated-quantitative-myocardial-perfusion-by-cardiovascular-magnetic-resonance-for-the-detection-of-functionally-significant-coronary-artery-disease
#3
JOURNAL ARTICLE
R Crawley, K P Kunze, X Milidonis, J Highton, S McElroy, S M Frey, D Hoefler, C Karamanli, N C K Wong, S J Backhaus, E Alskaf, R Neji, C M Scannell, S Plein, A Chiribiri
AIMS: Current assessment of myocardial ischaemia from stress perfusion cardiovascular magnetic resonance (SP-CMR) largely relies on visual interpretation. This study investigated the use of high-resolution free-breathing SP-CMR with automated quantitative mapping in the diagnosis of coronary artery disease (CAD). Diagnostic performance was evaluated against invasive coronary angiography (ICA) with fractional flow reserve (FFR) measurement. METHODS & RESULTS: Seven-hundred and three patients were recruited for SP-CMR using the research sequence at 3 Tesla...
March 25, 2024: European Heart Journal Cardiovascular Imaging
https://read.qxmd.com/read/38525609/optical-coherence-tomography-based-functional-stenosis-assessment-fusion-a-prospective-multicenter-trial
#4
JOURNAL ARTICLE
Allen Jeremias, Akiko Maehara, Mitsuaki Matsumura, Richard A Shlofmitz, Aziz Maksoud, Takashi Akasaka, Hiram G Bezerra, William F Fearon, Habib Samady, Bruce Samuels, Joshua Rapkin, Ajay Gopinath, Nutte Tarn Teraphongphom, Jana Buccola, Ziad A Ali
BACKGROUND: Intravascular imaging and intracoronary physiology may both be used to guide and optimize percutaneous coronary intervention; however, they are rarely used together. The virtual flow reserve (VFR) is an optical coherence tomography (OCT)-based model of fractional flow reserve (FFR) facilitating the assessment of the physiological significance of coronary lesions. We aimed to validate the VFR assessment of intermediate coronary artery stenoses. METHODS: FUSION (Validation of OCT-Based Functional Diagnosis of Coronary Stenosis) was a multicenter, prospective, observational study comparing OCT-derived VFR to invasive FFR...
March 25, 2024: Circulation. Cardiovascular Interventions
https://read.qxmd.com/read/38519823/lesion-of-slit-like-stenosis-underestimated-by-fractional-flow-reserve-based-on-computed-tomography-images
#5
JOURNAL ARTICLE
Tetsuya Matsuyama, Tatsuhiro Fujimura, Takayuki Okamura
This case report discusses a 74-year-old man presenting with angina pectoris. Coronary computed tomography angiography suggested only mild stenosis in the mid left anterior descending artery (LAD), with fractional flow reserve based on computed tomography images (FFRct) value of 0.87. However, coronary angiography revealed slit-like stenosis in the mid LAD, and the invasive fractional flow reserve (FFR) was measured at 0.72, demonstrating a deviation from the FFRct value.
March 23, 2024: International Journal of Cardiovascular Imaging
https://read.qxmd.com/read/38518962/diagnosis-and-treatment-of-ischemia-producing-coronary-stenoses-improves-5-year-survival-of-patients-undergoing-major-vascular-surgery
#6
JOURNAL ARTICLE
Dainis K Krievins, Edgars Zellans, Gustavs Latkovskis, Indulis Kumsars, Agate K Krievina, Sanda Jegere, Andrejs Erglis, Aigars Lacis, Erika Plopa, Peteris Stradins, Patricija Ivanova, Christopher K Zarins
BACKGROUND: Patients undergoing vascular surgery procedures have poor long-term survival due to coexisting coronary artery disease (CAD) which is often asymptomatic, undiagnosed and undertreated. We sought to determine whether pre-operative diagnosis of asymptomatic (silent) coronary ischemia using coronary CT -derived fractional flow reserve (FFRCT ) together with post-operative ischemia-targeted coronary revascularization can reduce adverse cardiac events and improve long-term survival following major vascular surgery...
March 20, 2024: Journal of Vascular Surgery
https://read.qxmd.com/read/38516003/fractional-flow-reserve-and-instantaneous-wave-free-ratio-in-coronary-artery-bypass-grafting-a-meta-analysis-and-practice-review
#7
REVIEW
R G Abbasciano, G R Layton, S Torre, N Abbaker, A Copperwheat, C Lucarelli, S Bhandari, S Nijjer, G Mikhail, R Casula, M Zakkar, A Viviano
OBJECTIVE: Fractional flow reserve (FFR) and instantaneous wave-free ratio (iFR) are invasive methods to assess the functional significance of intermediate severity coronary lesions. Both indexes have been extensively validated in clinical trials in guiding revascularisation in patients with stable ischaemic heart disease undergoing percutaneous coronary intervention (PCI) with improved clinical outcomes. However, the role of these tools in coronary artery bypass grafting (CABG) is less clear...
2024: Frontiers in Cardiovascular Medicine
https://read.qxmd.com/read/38511178/energy-loss-is-related-to-ct-fractional-flow-reserve-progression-in-type-2-diabetes-mellitus-patients
#8
JOURNAL ARTICLE
Nobuo Tomizawa, Shinichiro Fujimoto, Daigo Takahashi, Yui Nozaki, Ruiheng Fan, Ayako Kudo, Yuko Kawaguchi, Kazuhisa Takamura, Makoto Hiki, Satoshi Kadowaki, Fuki Ikeda, Kanako K Kumamaru, Hirotaka Watada, Tohru Minamino, Shigeki Aoki
BACKGROUND: We aimed to investigate the diagnostic value of energy loss (EL) and baseline CT fractional flow reserve (CT-FFR) computed using computational fluid dynamics to predict functional progression of coronary stenosis in patients with type 2 diabetes mellitus. METHODS: This single-center prospective study included 61 patients with type 2 diabetes mellitus (mean age, 61 years ±9 [SD]; 43 men) showing 20-70 % stenosis who underwent serial coronary CT performed at 2-year interval between October 2015 and March 2020...
November 2023: American heart journal plus: cardiology research and practice
https://read.qxmd.com/read/38510744/prognostic-differences-between-physiology-guided-percutaneous-coronary-intervention-and-optimal-medical-therapy-in-coronary-artery-disease-a-systematic-review-and-meta-analysis
#9
REVIEW
Utsho Islam, Muhammad Sabbah, Burcu T Özbek, Jasmine M Madsen, Jacob T Lønborg, Thomas Engstrøm
BACKGROUND: Intracoronary physiology, particularly fractional flow reserve (FFR), has been used as a guide for revascularization for patients with coronary artery disease (CAD). The optimal treatment in the physiological grey-zone area has been unclear and remains subject to ongoing debate. METHODS: We conducted a systematic review of randomized controlled trials and observational studies comparing the prognostic effect of percutaneous coronary revascularization (PCI) and optimal medical therapy (OMT) in patients with CAD...
February 2024: American heart journal plus: cardiology research and practice
https://read.qxmd.com/read/38510505/clinical-effects-of-physiologic-lesion-testing-in-influencing-treatment-strategy-for-multi-vessel-coronary-artery-disease
#10
JOURNAL ARTICLE
Harsh Rawal, Tung D Nguyen, Efehi Igbinomwanhia, Lloyd W Klein
BACKGROUND: The application of fractional flow reserve (FFR) and instantaneous wave-free ratio (iFR) in multivessel coronary artery disease (CAD) patients has not been definitively explored. We herein assessed how treatment strategies were decided based on FFR/iFR values in vessels selected clinically. Specifically, we sought to determine whether treatment selection was based on whether the vessel tested was the clinical target stenosis. METHODS: 270 consecutive patients with angiographically determined multivessel disease who underwent FFR/iFR testing were included...
April 2024: American heart journal plus: cardiology research and practice
https://read.qxmd.com/read/38509396/angiography-derived-physiological-assessment-after-percutaneous-coronary-intervention-of-chronic-total-occlusions
#11
JOURNAL ARTICLE
Gianluca Castaldi, Alice Benedetti, Enrico Poletti, Alice Moroni, Benjamin Scott, Paul Vermeersch, Carlo Zivelonghi, Johan Bennett, Pierfrancesco Agostoni
Scant data exploring potential suboptimal physiological results after angiographic successful percutaneous coronary intervention (PCI) of chronic total occlusion (CTO) are available. Sixty cases of successful CTO-PCI were selected for this retrospective analysis. Post-CTO-PCI angiography-based fractional flow reserve was computed using the Murray-based fractional flow reserve (μFR) software. Vessel-specific μFR, residual trans-stent gradient (TSG) and corrected TSGstent were calculated. In physiological suboptimal results (μFR < 0...
March 21, 2024: International Journal of Cardiovascular Imaging
https://read.qxmd.com/read/38502738/imaging-based-ffr-how-many-steps-toward-replacement-for-wire-based-ffr-on-a-journey-of-a-thousand-miles
#12
EDITORIAL
Takayuki Warisawa, Takashi Akasaka
No abstract text is available yet for this article.
March 2024: Circulation. Cardiovascular Imaging
https://read.qxmd.com/read/38502735/diagnostic-performance-of-angiography-derived-quantitative-flow-ratio-in-complex-coronary-lesions
#13
JOURNAL ARTICLE
Xianpeng Wu, Kan Wang, Guohua Li, Jie Wu, Jun Jiang, Feng Gao, Lingjun Zhu, Qiyuan Xu, Xinhong Wang, Mengxi Xu, Hui Chen, Longhui Ma, Xianjun Han, Nan Luo, Shengxian Tu, Jian'an Wang, Xinyang Hu
BACKGROUND: Quantitative flow ratio derived from computed tomography angiography (CT-QFR) and invasive coronary angiography (Murray law-based quantitative flow ratio [μQFR]) are novel approaches enabling rapid computation of fractional flow reserve without the use of pressure guidewires and vasodilators. However, the feasibility and diagnostic performance of both CT-QFR and μQFR in evaluating complex coronary lesions remain unclear. METHODS: Between September 2014 and September 2021, 240 patients with 30% to 90% coronary diameter stenosis who underwent both coronary computed tomography angiography and invasive coronary angiography with fractional flow reserve within 60 days were retrospectively enrolled...
March 2024: Circulation. Cardiovascular Imaging
https://read.qxmd.com/read/38496873/deep-learning-based-coronary-artery-calcium-score-to-predict-coronary-artery-disease-in-type-2-diabetes-mellitus
#14
JOURNAL ARTICLE
Jingcheng Hu, Guangyu Hao, Jialiang Xu, Ximing Wang, Meng Chen
BACKGROUND: Coronary artery disease (CAD) in type 2 diabetes mellitus (T2DM) patients often presents diffuse lesions, with extensive calcification, and it is time-consuming to measure coronary artery calcium score (CACS). OBJECTIVES: To explore the predictive ability of deep learning (DL)-based CACS for obstructive CAD and hemodynamically significant CAD in T2DM. METHODS: 469 T2DM patients suspected of CAD who accepted CACS scan and coronary CT angiography between January 2013 and December 2020 were enrolled...
March 30, 2024: Heliyon
https://read.qxmd.com/read/38496257/association-between-vessel-specific-coronary-aggregated-plaque-burden-agatston-score-and-hemodynamic-significance-of-coronary-disease-the-captivate-study
#15
JOURNAL ARTICLE
Avedis Ekmejian, Nicklas Howden, April Eipper, Usaid Allahwala, Michael Ward, Ravinay Bhindi
BACKGROUND: CT coronary angiography (CTCA) is a guideline-endorsed assessment for patients with stable angina and suspected coronary disease. Although associated with excellent negative predictive value in ruling out obstructive coronary disease, there are limitations in the ability of CTCA to predict hemodynamically significant coronary disease. The CAPTivAte study aims to assess the utility of Aggregated Plaque Burden (APB) in predicting ischemia based on Fractional Flow Reserve (FFR)...
April 2024: IJC Heart & Vasculature
https://read.qxmd.com/read/38494324/successful-treatment-of-focal-renal-artery-fibromuscular-dysplasia-by-balloon-dilatation-demonstrated-via-fractional-flow-reserve
#16
Xuhe Gong, Jixuan Liu, Daokuo Yao, Rongchong Huang
We present a rare case of fibromuscular dysplasia (FMD) manifesting in the mid segment of right renal artery, which led to the development of refractory hypertension. The patient received balloon angioplasty to a severe lesion on the middle of right renal artery and subsequently had normalisation of blood pressures. Fractional flow reserve (FFR) detection of the renal artery before and after balloon dilatation was 0.71 and 0.98, respectively. The patient showed renal artery stenosis (RAS) with distal tumour-like dilatation, and multiple tortuosity and stenosis in carotid artery and coronary artery...
November 2023: Clinical Medicine: Journal of the Royal College of Physicians of London
https://read.qxmd.com/read/38489035/hemodynamic-impairments-of-evaluating-symptomatic-intracranial-atherosclerotic-stenosis-using-quantitative-flow-ratio-on-digital-subtraction-angiography-a%C3%A2-comparison-with-computed-tomography-perfusion-mri-and-fractional-flow-reserve
#17
JOURNAL ARTICLE
Yingchun Wu, Feng Gao, Honglin Feng
PURPOSE: Cerebral hemodynamics are important for the management of intracranial atherosclerotic stenosis (ICAS). The quantitative flow ratio (QFR) is a novel angiography-derived index for assessing the functional relevance of ICAS without pressure wires and adenosine. Good diagnostic yield with the hyperemic fractional flow reserve (FFR) have been reported, while data on the comparison of QFR to FFR are scarce. METHODS: In this prospective study 56 patients with anterior circulation symptomatic ICAS who received endovascular treatment were included...
March 15, 2024: Clinical Neuroradiology
https://read.qxmd.com/read/38483420/development-and-validation-of-a-quantitative-coronary-ct-angiography-model-for-diagnosis-of-vessel-specific-coronary%C3%A2-ischemia
#18
JOURNAL ARTICLE
Nick S Nurmohamed, Ibrahim Danad, Ruurt A Jukema, Ruben W de Winter, Robin J de Groot, Roel S Driessen, Michiel J Bom, Pepijn van Diemen, Gianluca Pontone, Daniele Andreini, Hyuk-Jae Chang, Richard J Katz, Erik S G Stroes, Hao Wang, Chung Chan, Tami Crabtree, Melissa Aquino, James K Min, James P Earls, Jeroen J Bax, Andrew D Choi, Paul Knaapen, Alexander R van Rosendael
BACKGROUND: Noninvasive stress testing is commonly used for detection of coronary ischemia but possesses variable accuracy and may result in excessive health care costs. OBJECTIVES: This study aimed to derive and validate an artificial intelligence-guided quantitative coronary computed tomography angiography (AI-QCT) model for the diagnosis of coronary ischemia that integrates atherosclerosis and vascular morphology measures (AI-QCTISCHEMIA ) and to evaluate its prognostic utility for major adverse cardiovascular events (MACE)...
February 29, 2024: JACC. Cardiovascular Imaging
https://read.qxmd.com/read/38483246/impact-of-smoking-on-coronary-volume-to-myocardial-mass-ratio-an-advance-registry-substudy
#19
JOURNAL ARTICLE
Kenneth R Holmes, Gaurav S Gulsin, Timothy A Fairbairn, Lynne Hurwitz-Koweek, Hitoshi Matsuo, Bjarne L Nørgaard, Jesper M Jensen, Niels-Peter Rønnow Sand, Koen Nieman, Jeroen J Bax, Gianluca Pontone, Kavitha M Chinnaiyan, Mark G Rabbat, Tetsuya Amano, Tomohiro Kawasaki, Takashi Akasaka, Hironori Kitabata, Campbell Rogers, Manesh R Patel, Geoffrey W Payne, Jonathon A Leipsic, Stephanie L Sellers
Purpose To examine the relationship between smoking status and coronary volume-to-myocardial mass ratio (V/M) among individuals with coronary artery disease (CAD) undergoing CT fractional flow reserve (CT-FFR) analysis. Materials and Methods In this secondary analysis, participants from the ADVANCE registry evaluated for suspected CAD from July 15, 2015, to October 20, 2017, who were found to have coronary stenosis of 30% or greater at coronary CT angiography (CCTA) were included if they had known smoking status and underwent CT-FFR and V/M analysis...
April 2024: Radiology. Cardiothoracic imaging
https://read.qxmd.com/read/38480675/improvement-in-the-estimation-of-perfusable-tissue-fraction-and-myocardial-flow-reserve-in-the-ischemic-myocardial-lesions-using-ecg-gated-dynamic-myocardial-pet-with-15-o-water
#20
JOURNAL ARTICLE
Ayaka Maruo, Keiichi Magota, Yamato Munakata, Kenji Hirata, Chietsugu Katoh
OBJECTIVE: Perfusable tissue fraction (PTF) and myocardial flow reserve (MFR) from 15 O-water dynamic positron emission tomography (PET) are parameters of myocardial viability. However, myocardial motion causes errors in these values. We aimed to develop accurate estimation of PTF and MFR in ischemic lesions using an electro-cardiogram (ECG)-gated dynamic myocardial PET with 15 O-water. METHODS: Twenty-seven patients with ischemic heart disease were enrolled. All patients underwent percutaneous coronary intervention (PCI) or coronary artery bypass grafting (CABG)...
March 13, 2024: Annals of Nuclear Medicine
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