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essential medicines for children

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https://www.readbyqxmd.com/read/28337081/a-comprehensive-list-of-items-to-be-included-on-a-pediatric-drug-monograph
#1
Lauren E Kelly, Shinya Ito, David Woods, Anthony J Nunn, Carol Taketomo, Matthijs de Hoog, Martin Offringa
OBJECTIVES: Children require special considerations for drug prescribing. Drug information summarized in a formulary containing drug monographs is essential for safe and effective prescribing. Currently, little is known about the information needs of those who prescribe and administer medicines to children. Our primary objective was to identify a list of important and relevant items to be included in a pediatric drug monograph. METHODS: Following the establishment of an expert steering committee and an environmental scan of adult and pediatric formulary monograph items, 46 participants from 25 countries were invited to complete a 2-round Delphi survey...
January 2017: Journal of Pediatric Pharmacology and Therapeutics: JPPT: the Official Journal of PPAG
https://www.readbyqxmd.com/read/28298279/the-potential-impact-of-animal-science-research-on-global-maternal-and-child-nutrition-and-health-a-landscape-review
#2
REVIEW
Jack Odle, Sheila K Jacobi, R Dean Boyd, Dale E Bauman, Russell V Anthony, Fuller W Bazer, Adam L Lock, Andrew C Serazin
High among the challenges facing mankind as the world population rapidly expands toward 9 billion people by 2050 is the technological development and implementation of sustainable agriculture and food systems to supply abundant and wholesome nutrition. In many low-income societies, women and children are the most vulnerable to food insecurity, and it is unequivocal that quality nutrition during the first 1000 d of life postconception can be transformative in establishing a robust, lifelong developmental trajectory...
March 2017: Advances in Nutrition
https://www.readbyqxmd.com/read/28290130/the-choosing-wisely-initiative-in-infectious-diseases
#3
REVIEW
Clara Lehmann, Reinhard Berner, Johannes R Bogner, Oliver A Cornely, Katja de With, Susanne Herold, Winfried V Kern, Sebastian Lemmen, Mathias W Pletz, Bernhard Ruf, Bernd Salzberger, Hans Jürgen Stellbrink, Norbert Suttorp, Andrew J Ullmann, Gerd Fätkenheuer, Norma Jung
OBJECTIVE: "Choosing Wisely" is a growing international campaign aiming at practice changes to improve patient health and safety by both, conduct of essential and avoidance of unnecessary diagnostic, preventive and therapeutic procedures. The goal is to create an easily recognizable and distributable list ("Choosing Wisely items") that addresses common over- and underuse in the management of infectious diseases. METHODS: The German Society of Infectious Diseases (DGI) participates in the campaign "Klug Entscheiden" by the German Society of Internal Medicine...
March 13, 2017: Infection
https://www.readbyqxmd.com/read/28282104/retrospective-analysis-of-emerging-drugs-use-in-a-quebec-women-s-and-children-s-university-hospital-and-perspectives-for-safe-and-optimal-drug-use
#4
Jennifer Corny, Elaine Pelletier, Denis Lebel, Jean-François Bussières
BACKGROUND: Only few medicines are licensed for children. The use of emerging drugs (unmarketed drug, off-label drug with poorly documented use, and/or costly drugs) might represent an essential alternative for pediatric patients. OBJECTIVES: The objective of the study was to assess emerging drug uses rate and profile in our women's and children's centre to support the implementation of an appropriate policy. METHODS: We identified retrospectively emerging drugs used between 2013-01-01 and 2014-02-28, using computerized pharmacist software extraction of drugs used...
March 10, 2017: Journal of Population Therapeutics and Clinical Pharmacology
https://www.readbyqxmd.com/read/28279184/the-most-used-medicinal-plants-by-communities-in-mahaboboka-amboronabo-mikoboka-southwestern-madagascar
#5
Tabita N Randrianarivony, Aro Vonjy Ramarosandratana, Tefy H Andriamihajarivo, Fortunat Rakotoarivony, Vololoniaina H Jeannoda, Armand Randrianasolo, Rainer W Bussmann
BACKGROUND: This paper reports a study undertaken in three remote communities (Mahaboboka, Amboronabo, Mikoboka), located in Sakaraha, Southwestern Madagascar. Not only villages are far away from sanitary infrastructures and doctors but drugs and consulting fees are unaffordable to villagers. They rely essentially on natural resources for health care as for most of rural areas in Madagascar. This paper aims to document medicinal plants used by communities in Sakaraha and to present the most important plant species used in traditional medicine...
March 9, 2017: Journal of Ethnobiology and Ethnomedicine
https://www.readbyqxmd.com/read/28276634/essential-medicines-lists-for-children-of-who-india-south-africa-and-eml-of-china-a-comparative-study
#6
Dan Liu, Jing Cheng, Ling-Li Zhang, You-Ping Li, Li-Nan Zeng, Chuan Zhang, Ge Gui
OBJECTIVE: Comparing the essential medicine lists for children and China national essential medicine list 2012, to provide the evidence for establishing essential medicine list for children in China. METHODS: Search the official websites of WHO and some other countries' ministry of health to get essential medicine lists for children (EMLc) that have already established. Compare the situation of updating, the number and classification of medicines, and the dosage forms in essential medicine lists for children and China national essential medicine list 2012...
December 16, 2016: Journal of Evidence-based Medicine
https://www.readbyqxmd.com/read/28237004/nuclear-medicine-in-pediatric-cardiology
#7
REVIEW
Ornella Milanesi, Giovanni Stellin, Pietro Zucchetta
Accurate cardiovascular imaging is essential for the successful management of patients with congenital heart disease (CHD). Echocardiography and angiography have been for long time the most important imaging modalities in pediatric cardiology, but nuclear medicine has contributed in many situations to the comprehension of physiological consequences of CHD, quantifying pulmonary blood flow symmetry or right-to-left shunting. In recent times, remarkable improvements in imaging equipments, particularly in multidetector computed tomography and magnetic resonance imaging, have led to the progressive integration of high resolution modalities in the clinical workup of children affected by CHD, reducing the role of diagnostic angiography...
March 2017: Seminars in Nuclear Medicine
https://www.readbyqxmd.com/read/28237000/dose-estimation-in-pediatric-nuclear-medicine
#8
REVIEW
Frederic H Fahey, Alison B Goodkind, Donika Plyku, Kitiwat Khamwan, Shannon E O'Reilly, Xinhua Cao, Eric C Frey, Ye Li, Wesley E Bolch, George Sgouros, S Ted Treves
The practice of nuclear medicine in children is well established for imaging practically all physiologic systems but particularly in the fields of oncology, neurology, urology, and orthopedics. Pediatric nuclear medicine yields images of physiologic and molecular processes that can provide essential diagnostic information to the clinician. However, nuclear medicine involves the administration of radiopharmaceuticals that expose the patient to ionizing radiation and children are thought to be at a higher risk for adverse effects from radiation exposure than adults...
March 2017: Seminars in Nuclear Medicine
https://www.readbyqxmd.com/read/28215250/prevalence-and-quality-of-life-and-sleep-in-children-and-adolescents-with-restless-legs-syndrome-willis-ekbom-disease
#9
Heidi Haueisen Sander, Alan Luiz Eckeli, Afonso Diniz Costa Passos, Leila Azevedo, Lucila Bizari Fernandes do Prado, Regina Maria França Fernandes
OBJECTIVE: To estimate the prevalence of restless legs syndrome/Willis-Ekbom disease (RLS/WED) and its impact on sleep and quality of life in children and adolescents. METHODS: This was a cross-sectional study conducted in the Municipality of Cássia dos Coqueiros, Brazil. Participants included 383 children and adolescents 5-17 years of age. A comparison group was randomly matched by gender and age with the RLS/WED-affected individuals, pairing one by one. RESULTS: Interviews were conducted for 383 individuals by a neurologist experienced in sleep medicine...
February 2017: Sleep Medicine
https://www.readbyqxmd.com/read/28207051/access-to-age-appropriate-essential-medicines-a-retrospective-survey-of-compounding-of-medicines-for-children-in-hospitals-in-nigeria-and-implications-for-policy-development
#10
Ebiowei Samuel F Orubu, Chinyere Okwelogu, Olabisi Opanuga, Tony Nunn, Catherine Tuleu
No abstract text is available yet for this article.
March 1, 2017: Health Policy and Planning
https://www.readbyqxmd.com/read/28182281/essential-medicines-for-children
#11
Hoppu Kalle
WHO defines Essential medicines as those that satisfy the priority health-care needs of the population (1). The right to Essential medicines has been considered an important component of the right to health. In the name of equity children should also have access to appropriate, available, affordable, and quality essential medicines they need, but children's essential medicines are too often missing. This article is protected by copyright. All rights reserved.
February 9, 2017: Clinical Pharmacology and Therapeutics
https://www.readbyqxmd.com/read/28119403/are-age-appropriate-antibiotic-formulations-missing-from-the-who-list-of-essential-medicines-for-children-a-comparison-study
#12
Verica Ivanovska, Hubert G Leufkens, Carin Ma Rademaker, Elizabeta Zisovska, Mariëlle W Pijnenburg, Liset van Dijk, Aukje K Mantel-Teeuwisse
OBJECTIVE: There is a global call for formulations, which are better suited for children of different age categories and in a variety of settings. One key public health area of interest is age-appropriate paediatric antibiotics. We aimed to identify clinically relevant paediatric formulations of antibiotics listed on pertinent formularies that were not on the WHO Essential Medicines List for Children (EMLc). METHODS: We compared four medicines lists versus the EMLc and contrasted paediatric antibiotic formulations in relation to administration routes, dosage forms and/or drug strengths...
January 24, 2017: Archives of Disease in Childhood
https://www.readbyqxmd.com/read/28105733/vitamin-d-supplementation-for-sickle-cell-disease
#13
REVIEW
Htoo Htoo Kyaw Soe, Adinegara Bl Abas, Nan Nitra Than, Han Ni, Jaspal Singh, Abdul Razzak Bin Mohd Said, Ifeyinwa Osunkwo
BACKGROUND: Sickle cell disease is a genetic chronic haemolytic and pro-inflammatory disorder. The clinical manifestations of sickle cell disease result from the presence of mutations on the beta globin genes that generate an abnormal haemoglobin product (called haemoglobin S) within the red blood cell. Sickle cell disease can lead to many complications such as acute chest syndrome, stroke, acute and chronic bone complications (including painful vaso-occlusive crisis, osteomyelitis, osteonecrosis and osteoporosis)...
January 20, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28097194/the-mystery-of-the-z-score
#14
REVIEW
Alexander E Curtis, Tanya A Smith, Bulat A Ziganshin, John A Elefteriades
Reliable methods for measuring the thoracic aorta are critical for determining treatment strategies in aneurysmal disease. Z-scores are a pragmatic alternative to raw diameter sizes commonly used in adult medicine. They are particularly valuable in the pediatric population, who undergo rapid changes in physical development. The advantage of the Z-score is its inclusion of body surface area (BSA) in determining whether an aorta is within normal size limits. Therefore, Z-scores allow us to determine whether true pathology exists, which can be challenging in growing children...
August 2016: Aorta (Stamford, Conn.)
https://www.readbyqxmd.com/read/28095824/community-based-health-care-is-an-essential-component-of-a-resilient-health-system-evidence-from-ebola-outbreak-in-liberia
#15
Kendra Siekmans, Salim Sohani, Tamba Boima, Florence Koffa, Luay Basil, Saïd Laaziz
BACKGROUND: Trained community health workers (CHW) enhance access to essential primary health care services in contexts where the health system lacks capacity to adequately deliver them. In Liberia, the Ebola outbreak further disrupted health system function. The objective of this study is to examine the value of a community-based health system in ensuring continued treatment of child illnesses during the outbreak and the role that CHWs had in Ebola prevention activities. METHODS: A descriptive observational study design used mixed methods to collect data from CHWs (structured survey, n = 60; focus group discussions, n = 16), government health facility workers and project staff...
January 17, 2017: BMC Public Health
https://www.readbyqxmd.com/read/28077477/the-global-asthma-network-rationale-and-methods-for-phase-i-global-surveillance-prevalence-severity-management-and-risk-factors
#16
Philippa Ellwood, M Innes Asher, Nils E Billo, Karen Bissell, Chen-Yuan Chiang, Eamon M Ellwood, Asma El-Sony, Luis García-Marcos, Javier Mallol, Guy B Marks, Neil E Pearce, David P Strachan
The Global Asthma Network (GAN), established in 2012, followed the International Study of Asthma and Allergies in Childhood (ISAAC). ISAAC Phase One involved over 700 000 adolescents and children from 156 centres in 56 countries; it found marked worldwide variation in symptom prevalence of asthma, rhinitis and eczema that was not explained by the current understanding of these diseases; ISAAC Phase Three involved over 1 187 496 adolescents and children (237 centres in 98 countries). It found that asthma symptom prevalence was increasing in many locations especially in low- and middle-income countries where severity was also high, and identified several environmental factors that required further investigation...
January 2017: European Respiratory Journal: Official Journal of the European Society for Clinical Respiratory Physiology
https://www.readbyqxmd.com/read/28073721/the-contribution-of-the-french-muskoka-fund-to-improving-access-to-essential-medicines-and-priority-health-products-for-mothers-and-children
#17
C Macé, J-B Nikiema
One objective of the French Muskoka Fund since 2011 has been to improve the availability of quality healthcare services for mothers and children and thus to contribute to the continued presence of essential drugs and affordable quality health products and to their rational use by healthcare personnel. This project thus contributed to reinforcing the work of the national regulatory authorities, guarantor of the quality of the products supplied to the populations, but also to strengthening the coordination of supplies at the country level...
November 1, 2016: Médecine et Santé Tropicales
https://www.readbyqxmd.com/read/28070339/approval-status-and-evidence-for-who-essential-medicines-for-children-in-the-united-states-united-kingdom-and-japan-a-cross-sectional-study
#18
Rumiko Shimazawa, Masayuki Ikeda
BACKGROUND: The WHO Model List of Essential Medicines for Children (EMLc) covers medicines for globally high-burden diseases. Regulatory approval in high-income countries ensures evidence and dosage form but usually focuses on diseases common in those countries and not in low- and middle-income countries. METHODS: This cross-sectional study assessed supporting evidence for the 346 medicines in the 5th WHO EMLc and their approval data from the United States, United Kingdom, and Japan...
2017: Journal of Pharmaceutical Policy and Practice
https://www.readbyqxmd.com/read/28060211/service-delivery-in-the-healthcare-and-educational-systems-for-children-following-traumatic-brain-injury-gaps-in-care
#19
Juliet Haarbauer-Krupa, Angela Ciccia, Jonathan Dodd, Deborah Ettel, Brad Kurowski, Angela Lumba-Brown, Stacy Suskauer
OBJECTIVE: To provide a review of evidence and consensus-based description of healthcare and educational service delivery and related recommendations for children with traumatic brain injury. METHODS: Literature review and group discussion of best practices in management of children with traumatic brain injury (TBI) was performed to facilitate consensus-based recommendations from the American Congress on Rehabilitation Medicine's Pediatric and Adolescent Task Force on Brain Injury...
January 5, 2017: Journal of Head Trauma Rehabilitation
https://www.readbyqxmd.com/read/28050392/paediatric-prescription-analysis-in-a-primary-health-care-institution
#20
Jinish Jose, Denny Devassykutty
INTRODUCTION: Paediatric prescription analysis was done by vari-ous studies in tertiary care centers but not much published data, at primary care level. The Medical Council of India introduced new prescription format and also antibiotic stewardship program was launched by Government of Kerala in the year 2015. So in these contexts this study was conducted. AIM: To analyse the patterns of prescriptions and drug dis-pensing in pediatric patients using WHO core drug use indicators and parameters in the prescription format prescribed by Medical Council of India...
November 2016: Journal of Clinical and Diagnostic Research: JCDR
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