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10 most useful medications in pediatrics

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https://www.readbyqxmd.com/read/28198758/medication-reconciliation-failures-in-children-and-young-adults-with-chronic-disease-during-intensive-and-intermediate-care
#1
Danielle D DeCourcey, Melanie Silverman, Esther Chang, Al Ozonoff, Carolyn Stickney, Darla Pichoff, Alexandra Oldershaw, Jonathan A Finkelstein
OBJECTIVES: Although medication reconciliation has become standard during hospital admission, rates of unintentional medication discrepancies during intensive care of pediatric patients with chronic disease are unknown. Such discrepancies are an important cause of adverse drug events in adults with chronic illness and are associated with unintentional discontinuation of chronic medications. We sought to determine the rate, type, timing, and predictors of potentially harmful unintentional medication discrepancies in children and young adults with chronic disease...
February 14, 2017: Pediatric Critical Care Medicine
https://www.readbyqxmd.com/read/28164411/medical-care-focused-time-study-of-the-care-for-medically-dependent-smid
#2
Tadashi Matsubasa, Hiroshi Mitsubuchi, Akihiko Kimura, Makoto Shinohara, Fumio Endo
BACKGROUND: Improvements in neonatal medicine and pediatric emergency medicine has led to increasing number of children with severe disabilities requiring medical care, such as tracheal suction, on a daily basis. Most of these children, discharged directly from hospitals to their parents' homes, need home medical support. To provide data for the establishment of appropriate support systems we analyzed the care for such children through a time study conducted at an institution. METHODS: We performed a minute-by -minute time study of the work of 33 staff members in a ward for patients (medically-dependent SMID) requiring frequent medical care over 48 hours in order to analyze patient care...
February 6, 2017: Pediatrics International: Official Journal of the Japan Pediatric Society
https://www.readbyqxmd.com/read/28159006/the-potential-influence-of-human-parainfluenza-viruses-detected-during-hospitalization-among-critically-ill-patients-in-kuwait-2013-2015
#3
Sahar Essa, Haya Al-Tawalah, Sarah AlShamali, Widad Al-Nakib
BACKGROUND: The four types of human parainfluenza viruses (PIV) are important causes of community-acquired pneumonia, particularly in children; however, limited information exists about the incidence of PIV in critically ill patients. The aim of this study is to describe the spectrum, incidence and clinical features of PIV-associated infections diagnosed during the hospital stay of patients admitted to pediatric intensive care unit (PICU) and intensive care unit (ICU) of 5 medical centers across Kuwait...
February 3, 2017: Virology Journal
https://www.readbyqxmd.com/read/28146185/-community-acquired-staphylococcus-aureus-isolated-from-paraguayan-children-clinical-phenotypic-and-genotypic-characterization
#4
Rosa Guillén, Letizia Carpinelli, Fátima Rodríguez, Héctor Castro, Beatriz Quíñónez, Ana Campuzano, María Macchi, Juana Ortellado, Patricia Almada, Lorena Grau, Mónica Rodríguez, Gladys Velázquez, Carmen Espínola, Gloría Samudio, Gloria Gómez, Wilma Basualdo
INTRODUCTION: The prevalence of Staphylococcus aureus in the community has increased, being the pediatric population the most affected. This fact highlights the need for epidemiological surveillance. AIM: To characterize clinical, phenotypic and genotypic isolates of S. aureus children's samples with community-acquired infections, collected in hospitals of Asuncion and the Central Department, between November 2009 and December 2010. MATERIALS AND METHODS: Descriptive and transverse analysis with analytical component...
December 2016: Revista Chilena de Infectología: órgano Oficial de la Sociedad Chilena de Infectología
https://www.readbyqxmd.com/read/28144123/state-of-simulation-in-healthcare-education-an-initial-survey-in-beijing
#5
Zichen Zhao, Pengfei Niu, Xiang Ji, Robert M Sweet
BACKGROUND AND OBJECTIVES: In 2013, medical error was the third leading cause of death in the United States.(1) In China, as in the case with the United States, training and assessment are developing as a strategy to reduce the occurrence of such errors. The objective of this study was to assess the current state of the use of simulation-based training in Beijing and to explore the barriers to further development. METHODS: This study included hospitals in Beijing accredited by the Standardized Residency Training (SRT) program...
January 2017: JSLS: Journal of the Society of Laparoendoscopic Surgeons
https://www.readbyqxmd.com/read/28134402/-severe-neutropenia-during-treatment-with-amoxicillin-clavulanic-acid-in-a-patient-on-regular-hemodialysis-treatment
#6
Nicola Spetrino, Marta Arazzi, Giorgia Di Fulvio, Federica Giunta, Xhensila Grabocka, Maria Olimpia Longo, Gabriella Micioni, Alessandro Pezzutto, Simona Silvestri, Marco Tondo, Giacinta Vigilante, Mario Bonomini
Beta-lactams are one of the most widely used antibiotics in respiratory diseases, both in adults and in the pediatric population. Their widespread use is also linked to the elevated tolerability and low risk of side effects that are generally not severe. We present here the case of a patient on regular haemodialysis pertaining to our Center who, after a seven-day treatment period with amoxicillin/clavulanic acid antibiotic therapy (medication originator), developed a framework of severe neutropenia (neutrophils till 10/mmc) resulting in hospitalization and the beginning of a specific diagnostic and therapeutic work-up...
November 2016: Giornale Italiano di Nefrologia: Organo Ufficiale Della Società Italiana di Nefrologia
https://www.readbyqxmd.com/read/28125548/finding-diagnostic-errors-in-children-admitted-to-the-picu
#7
Maria Caridad Davalos, Kenya Samuels, Ashley N D Meyer, Satid Thammasitboon, Moushumi Sur, Kevin Roy, Aymer Al-Mutairi, Hardeep Singh
OBJECTIVES: To determine whether the Safer Dx Instrument, a structured tool for finding diagnostic errors in primary care, can be used to reliably detect diagnostic errors in patients admitted to a PICU. DESIGN AND SETTING: The Safer Dx Instrument consists of 11 questions to evaluate the diagnostic process and a final question to determine if diagnostic error occurred. We used the instrument to analyze four "high-risk" patient cohorts admitted to the PICU between June 2013 and December 2013...
January 25, 2017: Pediatric Critical Care Medicine
https://www.readbyqxmd.com/read/28088248/the-spectrum-of-rheumatic-in-patient-diagnoses-at-a-pediatric-hospital-in-kenya
#8
Angela Migowa, Inés Colmegna, Carol Hitchon, Eugene Were, Evelyn Ng'ang'a, Thomas Ngwiri, John Wachira, Sasha Bernatsky, Rosie Scuccimarri
BACKGROUND: Pediatric rheumatic diseases are chronic illnesses that can cause considerable disease burden to children and their families. There is limited epidemiologic data on these diseases in East Africa. The aim of this study was to assess the spectrum of pediatric rheumatic diagnoses in an in-patient setting and determine the accuracy of ICD-10 codes in identifying these conditions. METHODS: Medical records from Gertrude's Children's Hospital in Kenya were reviewed for patients diagnosed with "diseases of the musculoskeletal system and connective tissue" as per ICD-10 diagnostic codes assigned at discharge between January and December 2011...
January 14, 2017: Pediatric Rheumatology Online Journal
https://www.readbyqxmd.com/read/28045622/use-of-minimal-residual-disease-assessment-to-redefine-induction-failure-in-pediatric-acute-lymphoblastic-leukemia
#9
David O'Connor, Anthony V Moorman, Rachel Wade, Jeremy Hancock, Ronald M R Tan, Jack Bartram, John Moppett, Claire Schwab, Katharine Patrick, Christine J Harrison, Rachael Hough, Nick Goulden, Ajay Vora, Sujith Samarasinghe
Purpose Our aim was to determine the role of end-of-induction (EOI) minimal residual disease (MRD) assessment in the identification and stratification of induction failure in patients with pediatric acute lymphoblastic leukemia (ALL) and to identify genetic abnormalities that drive disease in these patients. Patients and Methods Analysis included 3,113 patients who were treated in the Medical Research Council UKALL2003 multicenter randomized trial (NCT00222612) between 2003 and 2011. MRD was measured by using standardized real-time quantitative PCR...
February 20, 2017: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
https://www.readbyqxmd.com/read/28009079/acute-disseminated-encephalomyelitis-in-china-singapore-and-japan-a-comparison-with-the-usa
#10
D L H Koelman, D C Benkeser, Y Xu, S X Neo, K Tan, M Katsuno, G Sobue, J Natsume, S Chahin, S S Mar, A Venkatesan, T Chitnis, G M Hoganson, A K Yeshokumar, P Barreras, B Majmudar, M Carone, F J Mateen
BACKGROUND AND PURPOSE: Ethnicity-related differences in the incidence of acute disseminated encephalomyelitis (ADEM) and other demyelinating diseases including multiple sclerosis and neuromyelitis optica spectrum disorders have been reported. Little is reported on the influence of ethnicity and geographical location in ADEM. METHODS: Medical records of patients who presented with ADEM (ICD-9 323.61 and 323.81) at large referral hospitals in China, Singapore and Japan (years 1992-2015) were retrospectively reviewed and data were collected in a centralized database...
February 2017: European Journal of Neurology: the Official Journal of the European Federation of Neurological Societies
https://www.readbyqxmd.com/read/27990158/chronic-functional-constipation-and-encopresis-in-children-in-relationship-with-the-psychosocial-environment
#11
Claudia Olaru, Smaranda Diaconescu, Laura Trandafir, Nicoleta Gimiga, Radian A Olaru, Gabriela Stefanescu, Gabriela Ciubotariu, Marin Burlea, Magdalena Iorga
Functional constipation is an issue for both the patient and his/her family, affecting the patient's psychoemotional balance, social relations, and their harmonious integration in the school environment. We aimed to highlight the connection between chronic constipation and encopresis and the patient's psychosocial and family-related situation. Material and Method. 57 patients with ages spanning from 6 to 15 were assessed within the pediatric gastroenterology ward. Sociodemographic, medical, and psychological data was recorded...
2016: Gastroenterology Research and Practice
https://www.readbyqxmd.com/read/27977506/management-of-pediatric-acute-mastoiditis-in-israel-nationwide-survey-among-otorhinolaryngologists-and-emergency-pediatricians
#12
Sharon Tamir Ovnat, Tal Marom, David Rekhtman, Michal Luntz
INTRODUCTION: Acute mastoiditis (AM) is a medical emergency that mandates prompt diagnosis and treatment. Nevertheless, its management often differs between otorhinolaryngologists (ORLs) and pediatricians (PEDs) working in emergency departments. We sought to characterize the similarities and differences between management protocols of these 2 disciplines. MATERIALS AND METHODS: A voluntary electronic questionnaire, including 17 items pertaining to pediatric AM management, was sent to all the 20 otorhinolaryngology and their corresponding pediatric emergency departments nationwide...
December 13, 2016: Pediatric Emergency Care
https://www.readbyqxmd.com/read/27940773/psychiatric-disorders-and-trends-in-resource-use-in-pediatric-hospitals
#13
Bonnie T Zima, Jonathan Rodean, Matt Hall, Naomi S Bardach, Tumaini R Coker, Jay G Berry
OBJECTIVE: To describe recent, 10-year trends in pediatric hospital resource use with and without a psychiatric diagnosis and examine how these trends vary by type of psychiatric and medical diagnosis cooccurrence. METHODS: A retrospective, longitudinal cohort analysis using hospital discharge data from 33 tertiary care US children's hospitals of patients ages 3 to 17 years from January 1, 2005 through December 31, 2014. The trends in hospital discharges, hospital days, and total aggregate costs for each psychiatric comorbid group were assessed by using multivariate generalized estimating equations...
November 2016: Pediatrics
https://www.readbyqxmd.com/read/27938389/hot-topics-urgent-priorities-and-ensuring-success-for-racial-ethnic-minority-young-investigators-in-academic-pediatrics
#14
REVIEW
Glenn Flores, Fernando S Mendoza, Elena Fuentes-Afflick, Jason A Mendoza, Lee Pachter, Juan Espinoza, Cristina R Fernandez, Danielle D P Arnold, Nicole M Brown, Kymberly M Gonzalez, Cynthia Lopez, Mikah C Owen, Kenya M Parks, Kimberly L Reynolds, Christopher J Russell
BACKGROUND: The number of racial/ethnic minority children will exceed the number of white children in the USA by 2018. Although 38% of Americans are minorities, only 12% of pediatricians, 5% of medical-school faculty, and 3% of medical-school professors are minorities. Furthermore, only 5% of all R01 applications for National Institutes of Health grants are from African-American, Latino, and American Indian investigators. Prompted by the persistent lack of diversity in the pediatric and biomedical research workforces, the Academic Pediatric Association Research in Academic Pediatrics Initiative on Diversity (RAPID) was initiated in 2012...
December 9, 2016: International Journal for Equity in Health
https://www.readbyqxmd.com/read/27931294/long-term-outcome-after-pediatric-intensive-care-unit-asthma-admissions
#15
Ibrahim Abu-Kishk, Sharon Polakow-Farkash, Arnon Elizur
BACKGROUND: Patients with asthma admitted to the pediatric intensive care unit (PICU) are often found to have had previous severe asthma exacerbations. OBJECTIVE: To prospectively evaluate the outcome of children after PICU admission. METHODS: Patients, ages 218 years, admitted to the PICU at Assaf Harofeh Medical Center over a 10-year period were assessed at a mean of 10 years after their admission and compared with matched patients admitted to the pediatric ward...
November 2016: Allergy and Asthma Proceedings:
https://www.readbyqxmd.com/read/27860526/medication-identification-in-pediatric-asthma-med-id-the-reliability-and-validity-of-a-novel-screening-tool
#16
Sean M Frey, I Diana Fernandez, Deborah J Ossip, Jill S Halterman
OBJECTIVES: To evaluate the reliability and validity of MED ID, a novel survey assessing caregiver-perceived ability to identify inhaled asthma medications. METHODS: We analyzed baseline data from the School-Based Asthma Care for Teens (SB-ACT) trial in Rochester, NY. Caregivers of adolescents with persistent asthma named the inhaled medications used by their child, and identified medications on a pictorial chart. Accurate identification was defined as completed matches between listed names and selected images...
November 18, 2016: Journal of Asthma: Official Journal of the Association for the Care of Asthma
https://www.readbyqxmd.com/read/27798810/emergence-delirium-in-pediatric-anesthesia
#17
REVIEW
Arthura D Moore, Doralina L Anghelescu
Emergence delirium (ED) is a complex of perceptual disturbances and psychomotor agitation that occurs most commonly in preschool-aged children in the early postanesthetic period. The incidence of ED varies between 10 and 80% in children and is perceived as a troublesome clinical situation by 42% of pediatric anesthesiologists. Although these events are often short lived, they increase the risk of self-injury and delayed discharge, require additional nursing staff and can increase medical care costs, all of which are causes for concern...
February 2017: Paediatric Drugs
https://www.readbyqxmd.com/read/27798639/new-findings-classification-and-long-term-follow-up-study-based-on-mri-characterization-of-brainstem-encephalitis-induced-by-enterovirus-71
#18
Hongwu Zeng, Feiqiu Wen, Wenxian Huang, Yungen Gan, Weibin Zeng, Ranran Chen, Yanxia He, Yonker Wang, Zaiyi Liu, Changhong Liang, Kelvin K L Wong
BACKGROUND: To report the diversity of MRI features of brainstem encephalitis (BE) induced by Enterovirus 71. This is supported by implementation and testing of our new classification scheme in order to improve the diagnostic level on this specific disease. METHODS: Neuroimaging of 91 pediatric patients who got EV71 related BE were hospitalized between March, 2010 to October, 2012, were analyzed retrospectively. All patients underwent pre- and post-contrast MRI scan...
2016: PloS One
https://www.readbyqxmd.com/read/27773937/effect-of-phentermine-on-weight-reduction-in-a-pediatric-weight-management-clinic
#19
J R Ryder, A Kaizer, K D Rudser, A Gross, A S Kelly, C K Fox
Phentermine is the most widely prescribed obesity medication in adults, yet studies of its use in the pediatric population are limited. We conducted a retrospective chart review of adolescents with obesity treated in a pediatric weight management clinic to examine the weight loss effectiveness of phentermine added to standard of care (SOC) lifestyle modification therapy versus SOC alone. All patients receiving phentermine plus SOC (n=25) were matched with a comparison group receiving only SOC (n=274). Differences at 1, 3 and 6 months were evaluated using generalized estimated equations adjusting for age, sex and baseline body mass index (BMI) and robust variance standard error estimates for confidence intervals and P-values...
January 2017: International Journal of Obesity: Journal of the International Association for the Study of Obesity
https://www.readbyqxmd.com/read/27767903/neurosurgical-sequelae-of-domestic-dog-attacks-in-children
#20
Ramesh Kumar, Frederic W B Deleyiannis, Corbett Wilkinson, Brent R O'Neill
OBJECTIVE The authors' goals in this study were to describe a series of dog attacks on children that required neurosurgical consultation and to better understand the pattern of injuries inflicted, the circumstances that place children at risk for attack, and the dog breeds involved. In addition, the authors review the surgical and medical management of these patients. METHODS The authors performed a retrospective review of all children requiring neurosurgical consultation for dog bite at a regional Level 1 pediatric trauma center over a 15-year period...
January 2017: Journal of Neurosurgery. Pediatrics
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