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10 most useful medications in pediatrics

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https://www.readbyqxmd.com/read/29770995/adolescent-and-young-adult-oncology-patients-in-france-heterogeneity-in-pathways-of-care
#1
Emmanuel Desandes, Laurence Brugières, Florence Molinié, Gautier Defossez, Patricia Delafosse, Karine Jehannin-Ligier, Michel Velten, Brigitte Trétarre, Brice Amadéo, Emilie Marrer, Anne-Sophie Woronoff, Olivier Ganry, Alain Monnereau, Tania d'Almeida, Xavier Troussard, Laetitia Daubisse-Marliac, Simona Bara, Anne-Valérie Guizard, Isabelle Baldi, Guy Launoy, Jacqueline Clavel, Brigitte Lacour
BACKGROUND: In order to evaluate at the population level the impact of the actions developed in France since 2004 to organize the care of adolescents and young adults (AYAs) with cancer, we conducted the present study to provide an unbiased view of the pathway of care of these patients. METHODS: Using a population-based registry, we conducted a review of all cases of cancer diagnosed during 2012 and 2013 in 15- to 24-year-old patients living in nineteen French administrative areas...
May 17, 2018: Pediatric Blood & Cancer
https://www.readbyqxmd.com/read/29742551/exploring-research-topics-and-trends-in-nursing-related-communication-in-intensive-care-units-using-social-network-analysis
#2
Youn-Jung Son, Soo-Kyoung Lee, SeJin Nam, Jae Lan Shim
This study used social network analysis to identify the main research topics and trends in nursing-related communication in intensive care units. Keywords from January 1967 to June 2016 were extracted from PubMed using Medical Subject Headings terms. Social network analysis was performed using Gephi software. Research publications and newly emerging topics in nursing-related communication in intensive care units were classified into five chronological phases. After the weighting was adjusted, the top five keyword searches were "conflict," "length of stay," "nursing continuing education," "family," and "nurses...
May 4, 2018: Computers, Informatics, Nursing: CIN
https://www.readbyqxmd.com/read/29738718/bilateral-thalamocortical-abnormalities-in-focal-cortical-dysplasia
#3
Arthur Rezayev, Henry A Feldman, Jacob Levman, Emi Takahashi
BACKGROUND AND PURPOSE: Focal cortical dysplasia (FCD), a congenital malformation of the neocortex and one of the most common causes of medication resistant epilepsy in pediatric populations, can be studied noninvasively by diffusion tensor imaging (DTI). The present study aimed to quantify changes in the thalamus and thalamocortical pathways with respect to fractional anisotropy (FA), apparent diffusion coefficient (ADC), volume, and other common measures. MATERIALS & METHODS: The study quantified data collected from pediatric patients with a prior diagnosis of FCD; 75 patients (35 females, 10...
May 5, 2018: Brain Research
https://www.readbyqxmd.com/read/29718343/dermatological-manifestations-in-pediatric-patients-with-inflammatory-bowel-diseases-on-anti-tnf-therapy
#4
Shilpa Sridhar, Ross M Maltz, Brendan Boyle, Sandra C Kim
Background: Anti-tumor necrosis factor (anti-TNF) therapies are effective treatments for inflammatory bowel diseases (IBD). However, infections, psoriasis, and eczema are potential manifestations. Descriptions of these are limited. Our aim was to characterize these skin manifestations in children with IBD on anti-TNF therapy. Methods: Our study is a retrospective review of IBD patients ranging in age from 6 to 18 years who were treated with anti-TNFs from 2010-2015...
April 27, 2018: Inflammatory Bowel Diseases
https://www.readbyqxmd.com/read/29705926/executive-functioning-heterogeneity-in-pediatric-adhd
#5
Michael J Kofler, Lauren N Irwin, Elia F Soto, Nicole B Groves, Sherelle L Harmon, Dustin E Sarver
Neurocognitive heterogeneity is increasingly recognized as a valid phenomenon in ADHD, with most estimates suggesting that executive dysfunction is present in only about 33%-50% of these children. However, recent critiques question the veracity of these estimates because our understanding of executive functioning in ADHD is based, in large part, on data from single tasks developed to detect gross neurological impairment rather than the specific executive processes hypothesized to underlie the ADHD phenotype...
April 28, 2018: Journal of Abnormal Child Psychology
https://www.readbyqxmd.com/read/29695585/mortality-after-pediatric-arterial-ischemic-stroke
#6
Lauren A Beslow, Michael M Dowling, Sahar M A Hassanein, John K Lynch, Dimitrios Zafeiriou, Lisa R Sun, Ilona Kopyta, Luigi Titomanlio, Anneli Kolk, Anthony Chan, Jose Biller, Eric F Grabowski, Abdalla A Abdalla, Mark T Mackay, Gabrielle deVeber
OBJECTIVES: Cerebrovascular disease is among the top 10 causes of death in US children, but risk factors for mortality are poorly understood. Within an international registry, we identify predictors of in-hospital mortality after pediatric arterial ischemic stroke (AIS). METHODS: Neonates (0-28 days) and children (29 days-<19 years) with AIS were enrolled from January 2003 to July 2014 in a multinational stroke registry. Death during hospitalization and cause of death were ascertained from medical records...
April 25, 2018: Pediatrics
https://www.readbyqxmd.com/read/29679911/the-effects-of-valproate-and-topiramate-use-on-serum-insulin-leptin-neuropeptide-y-and-ghrelin-levels-in-epileptic-children
#7
Nafiye Polat Çiçek, Tülay Kamaşak, Mine Serin, Aysenur Okten, Ahmet Alver, Ali Cansu
PURPOSE: Although some drugs used in the treatment of epilepsy are known to affect body weight, the hormonal factors responsible have not been sufficiently described. The purpose of this study was to compare insulin, leptin, neuropeptide Y and ghrelin levels in children with epilepsy receiving monotherapy with topiramate (TPM) and valproic acid (VPA), the drugs whose effects on body weight have been most discussed, with those of a control group. METHOD: 48 patients (25 VPA, 23 TPM) aged between 6 and 15...
April 11, 2018: Seizure: the Journal of the British Epilepsy Association
https://www.readbyqxmd.com/read/29659416/a-pilot-randomized-controlled-trial-of-an-intervention-to-promote-psychological-well-being-in-critically-ill-children-soothing-through-touch-reading-and-music
#8
Janet E Rennick, Robyn Stremler, Linda Horwood, Marilyn Aita, Tanya Lavoie, Annette Majnemer, Marie Antonacci, Alyssa Knox, Evelyn Constantin
OBJECTIVES: To examine the feasibility and acceptability of a PICU Soothing intervention using touch, reading, and music. DESIGN: Nonblinded, pilot randomized controlled trial. SETTING: The PICU and medical-surgical wards of one Canadian pediatric hospital. PATIENTS: Twenty PICU patients age 2-14 years old and their parents, randomized to an intervention group (n = 10) or control group (n = 10). INTERVENTION: PICU Soothing consisted of: 1) parental comforting (touch and reading), followed by 2) a quiet period with music via soft headbands, administered once daily throughout hospitalization...
April 13, 2018: Pediatric Critical Care Medicine
https://www.readbyqxmd.com/read/29624839/proximal-hypospadias-treated-with-a-transverse-preputial-island-tube-long-term-functional-sexual-and-cosmetic-outcomes
#9
S P Rynja, T P V M de Jong, J L H R Bosch, L M O de Kort
OBJECTIVE: To study long-term urinary and sexual function and cosmetic outcomes in adult hypospadias patients, who underwent a single-stage transverse preputial island tube (TPIT) in childhood. Long-term data on outcomes of proximal hypospadias patients with severe coexisting curvature and insufficient urethral plate are scarce, but are necessary to decide which repair technique is most beneficial. PATIENTS AND METHODS: Proximal hypospadias patients operated with TPIT were compared to distal hypospadias (DH) patients and to a control group of male medical students...
April 6, 2018: BJU International
https://www.readbyqxmd.com/read/29610163/recanalization-of-occluded-central-veins-in-a-parenteral-nutrition-dependent-child-with-no-access
#10
Patrick M Sullivan, Russell Merritt, Juan Carlos Pelayo, Frank F Ing
Central venous thromboses are common and pose challenges in the care of chronically ill pediatric patients. Among patients with intestinal failure (most commonly because of short bowel syndrome) who depend on parenteral nutrition, progressive loss of central venous access sites is a potentially fatal complication. We present the case of a 5-year-old girl with parenteral nutrition-dependent short bowel syndrome and no remaining standard central venous access sites despite medical anticoagulation, in whom angioplasty and stent implantations were used to reconstruct chronically occluded central veins...
April 2018: Pediatrics
https://www.readbyqxmd.com/read/29603705/comparison-of-visual-analog-scale-scores-in-pain-assessment-during-pulpotomy-using-different-injection-materials-in-children-aged-6-to-8-and-8-to-10-years
#11
Donya Alinejhad, Zahra Bahrololoomi, Alireza Navabazam, M Ali Asayesh
AIM: Proper anesthesia and pain management during treatment are most important concerns in dentistry for people of all ages, especially children. This study compared the success rate of lidocaine block with articaine buccal infiltration during anesthesia of the primary mandibular second molars in children aged 6 to 8 and 8 to 10 years. MATERIALS AND METHODS: The present clinical trial was conducted on 40 children aged 6 to 8 and 8 to 10 years who were referred to the Department of Pediatrics of the Faculty of Dentistry at Shahid Sadoughi University of Medical Sciences in Yazd (Islamic Republic of Iran) and needed to be treated with pulpotomy on both primary mandibular second molars...
March 1, 2018: Journal of Contemporary Dental Practice
https://www.readbyqxmd.com/read/29582079/2017-update-on-pediatric-medical-overuse-a-review
#12
Eric R Coon, Paul C Young, Ricardo A Quinonez, Daniel J Morgan, Sanket S Dhruva, Alan R Schroeder
Importance: Medical overuse has historically focused on adult health care, but interest in how children are affected by medical overuse is increasing. This review examines important research articles published in 2016 that address pediatric overuse. Observations: A structured search of PubMed and a manual review of the tables of contents of 10 journals identified 169 articles related to pediatric overuse published in 2016, from which 8 were selected based on the quality of methods and potential harm to patients in terms of prevalence and magnitude...
March 26, 2018: JAMA Pediatrics
https://www.readbyqxmd.com/read/29577092/assessment-of-maximal-isometric-hand-grip-strength-in-school-aged-children
#13
Jakub S Gąsior, Mariusz Pawłowski, Craig A Williams, Marek J Dąbrowski, Eugene A Rameckers
Background: Hand grip strength (HGS) test is commonly used as an indicator of overall muscle strength in medical and sport practices. Recently, several studies have proposed that the measurement of the maximal HGS depends on dynamometer's handle position. The aim of the present study was to identify the optimal handle position to obtain maximal HGS using the hand grip dynamometer (HGD) for school-aged children. Methods: HGS was assessed with the Jamar digital HGD...
2018: Open Medicine (Warsaw, Poland)
https://www.readbyqxmd.com/read/29538358/prenatal-exposure-to-maternal-depression-and-anxiety-on-imprinted-gene-expression-in-placenta-and-infant-neurodevelopment-and-growth
#14
Julia F Litzky, Maya A Deyssenroth, Todd M Everson, Barry M Lester, Luca Lambertini, Jia Chen, Carmen J Marsit
BACKGROUND: Depression and/or anxiety during pregnancy have been associated with impaired fetal growth and neurodevelopmental. Because placental imprinted genes play a central role in fetal development and respond to environmental stressors, we hypothesized that imprinted gene expression would be affected by prenatal depression and anxiety. METHODS: Placental gene expression was compared between mothers with prenatal depression and/or anxiety/obsessive compulsive disorder/panic and control mothers without psychiatric history (n=458) in the Rhode Island Child Health Study...
March 14, 2018: Pediatric Research
https://www.readbyqxmd.com/read/29513362/a-multisite-intervention-for-pediatric-community-acquired-pneumonia-in-community-settings
#15
Corrie E McDaniel, Wren Haaland, Joshua Parlaman, Chuan Zhou, Arti D Desai
OBJECTIVES: The majority of children with community-acquired pneumonia (CAP) are primarily evaluated in community hospital emergency departments (EDs); however, studies on the management of pediatric CAP have largely targeted care provided in freestanding children's hospital EDs or inpatient settings. The objectives of this study were to examine whether implementation of a CAP pathway within three community hospital EDs and inpatient units improved process measures related to appropriate laboratory testing and antibiotic prescribing and to compare performance on these measures between the community hospitals and a freestanding children's hospital...
March 7, 2018: Academic Emergency Medicine: Official Journal of the Society for Academic Emergency Medicine
https://www.readbyqxmd.com/read/29507952/effect-of-a-health-care-professional-communication-training-intervention-on-adolescent-human-papillomavirus-vaccination-a-cluster-randomized-clinical-trial
#16
Amanda F Dempsey, Jennifer Pyrznawoski, Steven Lockhart, Juliana Barnard, Elizabeth J Campagna, Kathleen Garrett, Allison Fisher, L Miriam Dickinson, Sean T O'Leary
Importance: The incidence of human papillomavirus (HPV)-related cancers is more than 35 000 cases in the United States each year. Effective HPV vaccines have been available in the United States for several years but are underused among adolescents, the target population for vaccination. Interventions to increase uptake are needed. Objective: To evaluate the effect of a 5-component health care professional HPV vaccine communication intervention on adolescent HPV vaccination...
March 5, 2018: JAMA Pediatrics
https://www.readbyqxmd.com/read/29478760/the-attributable-cost-of-catheter-associated-urinary-tract-infections-in-the-united-states-a-systematic-review
#17
Christopher S Hollenbeak, Amber L Schilling
BACKGROUND: Catheter-associated urinary tract infections (CAUTIs) are the most common healthcare-acquired condition. The attributable cost of CAUTIs is frequently cited to be approximately $1,000. However, there is a paucity of recent literature that confirms this estimate. The purpose of this study was to perform a systematic review of the literature that estimates the attributable cost of CAUTIs in the United States. METHODS: A systematic review was conducted using Pubmed...
February 22, 2018: American Journal of Infection Control
https://www.readbyqxmd.com/read/29477987/declarations-of-conflict-of-interest-are-still-inadequate
#18
Lars H Breimer, Torbjörn K Nilsson, Michael E Breimer
Declaration of conflicts of interest (COI, understood mainly as financial) in medical publications is long established. Most journals refer only to the guidelines of the International Committee of Medical Journal Editors (ICMJE) but not to those of the WAME (World Association of Medical Editors). We surveyed 17 journals and found only one (BJOG), which explicitly mentioned "religious interest" as an example of a possible COI and one other journal included "personal belief" (Journal of Obstetrics and Gynaecology of India) as a COI...
February 7, 2018: Indian Journal of Medical Ethics
https://www.readbyqxmd.com/read/29461017/medication-adherence-in-pediatric-asthma-a-systematic-review-of-the-literature
#19
REVIEW
Wendy N Gray, Mallory Netz, Andrew McConville, David Fedele, Scott T Wagoner, Megan R Schaefer
OBJECTIVE: To provide a systematic review of correlates of adherence to inhaled corticosteroids (ICS) in pediatric asthma across the individual, family, community, and healthcare system domains. METHODS: Articles assessing medication adherence in pediatric asthma published from 1997 to 2016 were identified using PsychINFO, Medline, and CINAHL. Search terms included asthma, compliance, self-management, adherence, child, and youth. Search results were limited to articles: 1) published in the US; 2) using a pediatric population (0-25 years old); and 3) presenting original data related to ICS adherence...
May 2018: Pediatric Pulmonology
https://www.readbyqxmd.com/read/29455676/evaluation-of-an-ophthalmoscopy-simulator-to-teach-funduscopy-skills-to-pediatric-residents
#20
Elizabeth Kouzmitcheva, Stephanie A Grover, Tara Berenbaum, Asim Ali, Adelle Atkinson, E Ann Yeh
BACKGROUND: Medical school and residency training in ophthalmoscopic evaluation is limited, reducing diagnostic accuracy. We sought to evaluate the efficacy of self-study using an ophthalmoscopy simulator to improve the technical motor skills involved in direct funduscopy in postgraduate pediatric residents. METHODS: In this randomized-controlled study, 17 pediatric residents (postgraduate years 1-3) were randomized to control (n=8) or intervention (n=9) groups...
February 19, 2018: Canadian Journal of Neurological Sciences. le Journal Canadien des Sciences Neurologiques
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