keyword
https://read.qxmd.com/read/38350507/long-term-pci-outcomes-in-chronic-versus-acute-coronary-syndromes-target-all-comers-trial
#21
JOURNAL ARTICLE
Kush P Patel, Alexandra J Lansky, Henning Kelbæk, Bo Xu, Niels van Royen, Thomas W Johnson, Richard Anderson, William Wijns, Andreas Baumbach
In the TARGET All Comers trial, the biodegradable-polymer sirolimus-eluting FIREHAWK stent (BP SES) was non-inferior to the durable-polymer everolimus-eluting XIENCE stent (DP EES) with respect to target lesion failure (TLF) at 1 and 5 years; however, long-term safety and efficacy in the setting of acute coronary syndromes (ACS) are not known. We sought to assess the long-term outcomes in ACS vs chronic coronary syndromes (CCS) with BP SES vs DP EES. The TARGET AC study was a multicenter, open-label, noninferiority trial of all comer patients randomized 1:1 to BP SES or DP EES (stratified by ST-elevation myocardial infarction and study site)...
February 11, 2024: American Journal of Cardiology
https://read.qxmd.com/read/38343372/evaluation-and-management-of-patients-with-coronary-chronic-total-occlusions-considered-for-revascularisation-a-clinical-consensus-statement-of-the-european-association-of-percutaneous-cardiovascular-interventions-eapci-of-the-esc-the-european-association-of
#22
JOURNAL ARTICLE
Alfredo R Galassi, Giuseppe Vadalà, Gerald S Werner, Bernard Cosyns, Georgios Sianos, Jonathan Hill, Dariusz Dudek, Eugenio Picano, Giuseppina Novo, Daniele Andreini, Bernhard L M Gerber, Ronny Buechel, Kambis Mashayekhi, Mathias Thielmann, Margaret B McEntegart, Beatriz Vaquerizo, Carlo Di Mario, Sinisa Stojkovic, Sigrid Sandner, Nikolaos Bonaros, Thomas F Lüscher
Chronic total occlusions (CTOs) of coronary arteries can be found in the context of chronic or acute coronary syndromes; sometimes they are an incidental finding in those apparently healthy individuals undergoing imaging for preoperative risk assessment. Recently, the invasive management of CTOs has made impressive progress due to sophisticated preinterventional assessment, including advanced non-invasive imaging, the availability of novel and dedicated tools for CTO percutaneous coronary intervention (PCI), and experienced interventionalists working in specialised centres...
February 5, 2024: EuroIntervention
https://read.qxmd.com/read/38326065/-comparison-among-different-flushing-media-for-intracoronary-imaging-with-optical-coherence-tomography
#23
JOURNAL ARTICLE
B Li, Z B Li, J P Wang, L Zhao, Z H Wang, J D Wu, B Liu
Objective: To explore the effects and safety of saline mixed 1∶1 with contrast medium (mixed medium) and pure heparinized saline as alternative media for optimal Optical Coherence Tomography (OCT) guided percutaneous coronary intervention (PCI). Methods: This single-center, prospective cohort study enrolled patients who underwent PCI with OCT guidance for chronic stable angina or acute coronary syndrome at the Department of Cardiology, the Second Hospital of Jilin University from October 2021 to August 2022...
February 24, 2024: Zhonghua Xin Xue Guan Bing za Zhi
https://read.qxmd.com/read/38293924/impact-of-cardiac-rehabilitation-health-insurance-coverage-on-cardiac-rehabilitation-use-in-korea-using-an-interrupted-time-series
#24
JOURNAL ARTICLE
Yu Shin Park, In Sun Song, Suk-Yong Jang, Chung Mo Nam, Eun-Cheol Park
BACKGROUND: Since 2017, the cardiac rehabilitation (CR) program in Korea has been included in the coverage provided by the National Health Insurance to alleviate financial burden. Our study aimed to identify changes in the CR program use according to the implementation of CR coverage. METHODS AND RESULTS: We obtained data from the electronic medical records of a tertiary hospital in Seoul, Korea from January 2014 to February 2020. Data from 2988 patients with acute coronary syndrome who underwent percutaneous coronary intervention were included...
January 31, 2024: Journal of the American Heart Association
https://read.qxmd.com/read/38290731/implementing-a-comprehensive-stemi-protocol-to-improve-care-metrics-and-outcomes-in-patients-with-in-hospital-stemi-an-observational-cohort-study
#25
JOURNAL ARTICLE
Christopher N Kanaan, Nicholas Kassis, Raunak M Nair, Anirudh Kumar, Chetan P Huded, Kathleen Kravitz, Grant W Reed, Amar Krishnaswamy, A Michael Lincoff, Jaikirshan Khatri, Rishi Puri, Khaled Ziada, Ravi Nair, Samir Kapadia, Umesh Khot
BACKGROUND: Patients who experience in-hospital ST-segment elevation myocardial infarction (iSTEMI) represent a uniquely high-risk cohort owing to delays in diagnosis, prolonged time to reperfusion and increased mortality. Quality initiatives aimed at improving the care of this vulnerable, yet understudied population are needed. METHODS: This study included consecutive patients with iSTEMI treated with percutaneous coronary intervention (PCI) between 1 January 2011 and 15 July 2019 at a single, tertiary referral centre...
January 30, 2024: Open Heart
https://read.qxmd.com/read/38278491/ten-year-outcomes-post-percutaneous-coronary-intervention-in-cardiac-transplant-recipients
#26
JOURNAL ARTICLE
Vinayak Nagaraja, Bradley R Lewis, Mandeep Singh
BACKGROUND: Cardiac allograft vasculopathy (CAV) is one of the major late causes of mortality in cardiac transplant recipients beyond the first year. Given the lack of longer term data for PCI in cardiac transplant recipients, we report ten year follow up of such cardiac transplant recipients who underwent PCI at Mayo Clinic. METHODS: A retropecitve observational study was conducted that included cardiac transplant recipients who underwent PCI at the Mayo Clinic...
January 24, 2024: International Journal of Cardiology
https://read.qxmd.com/read/38270189/impact-of-untreated-chronic-obstructive-coronary-artery-disease-on-outcomes-after-transcatheter-aortic-valve-replacement
#27
JOURNAL ARTICLE
Ian Persits, Habib Layoun, Nicholas P Kondoleon, Nikolaos Spilias, Osamah Badwan, Joseph Sipko, James J Yun, Ankur Kalra, Iryna Dykun, Larisa G Tereshchenko, Amar Krishnaswamy, Grant W Reed, Samir R Kapadia, Rishi Puri
BACKGROUND AND AIMS: In transcatheter aortic valve replacement (TAVR) recipients, the optimal management of concomitant chronic obstructive coronary artery disease (CAD) remains unknown. Some advocate for pre-TAVR percutaneous coronary intervention, while others manage it expectantly. The aim of this study was to assess the impact of varying degrees and extent of untreated chronic obstructive CAD on TAVR and longer-term outcomes. METHODS: The authors conducted a retrospective cohort study of TAVR recipients from January 2015 to November 2021, separating patients into stable non-obstructive or varying degrees of obstructive CAD...
January 25, 2024: European Heart Journal
https://read.qxmd.com/read/38266797/patients-aged-90-years-and-above-with-acute-coronary-syndrome-in-the-cardiac-intensive-care-unit-management-and-outcomes
#28
JOURNAL ARTICLE
Dhruv Sarma, Mitchell Padkins, Ryan Smith, Courtney E Bennett, Joseph G Murphy, Malcolm R Bell, Abdulla A Damluji, Nandan S Anavekar, Gregory W Barsness, Jacob C Jentzer
Limited data exist regarding outcomes after coronary angiography (CAG) and percutaneous coronary intervention (PCI) in patients aged ≥90 years admitted to the cardiac intensive care unit (CICU) with acute coronary syndrome (ACS). We studied sequential CICU patients ≥90 years admitted with ACS from 2007-2018. Three therapeutic approaches were defined: 1) No CAG; 2) CAG without PCI (CAG/No PCI); and 3) CAG with PCI (CAG/PCI). In-hospital mortality was evaluated using multivariable logistic regression...
January 22, 2024: American Journal of Cardiology
https://read.qxmd.com/read/38247436/the-characteristic-of-acute-coronary-syndromes-of-patients-with-multivessel-coronary-artery-disease-in-centers-with-and-without-cardiac-surgery-on-site
#29
JOURNAL ARTICLE
Krzysztof Brust, Karol Śmiech, Kamil Bujak, Tomasz Roleder, Mariusz Gąsior
BACKGROUND: Multivessel disease (MVD) is diagnosed in a fair number of patients with acute coronary syndrome (ACS). There are 36 cardiac-surgery (CS) centres and 157 catheterization laboratories dedicated to treat ACS in Poland. The aim of the study was to analyze MVD patient outcomes presented with ACS in centers with or without CS on-site. METHODS: The present study is a retrospective analysis (2017-2020) of MVD ACS patients (n = 4618) outcomes between those treated in centers with CS on site (n = 595) and those without CS (n = 4023)...
January 22, 2024: Cardiology Journal
https://read.qxmd.com/read/38245724/randomized-evaluation-of-5-month-ticagrelor-monotherapy-after-1-month-dual-antiplatelet-therapy-in-patients-with-acute-coronary-syndrome-treated-with-drug-coated-balloons-rec-cagefree-ii-trial-rationale-and-design
#30
JOURNAL ARTICLE
Chao Gao, Bin Zhu, Jianzheng Liu, Zhiwei Jiang, Tao Hu, Qiong Wang, Yi Liu, Ming Yuan, Fei Li, Ruining Zhang, Jielai Xia, Yoshinobu Onuma, Duolao Wang, Patrick Serruys, Ling Tao
BACKGROUND: Patients treated with drug-coated balloons (DCB) have the theoretical advantage of adopting a low-intensity antiplatelet regimen due to the absence of struts and polymers. Nevertheless, the optimal antiplatelet strategy for patients undergoing DCB-only treatment remains a topic of debate and has not been investigated in randomized trials. METHODS: The REC-CAGEFREE II is an investigator-initiated, prospective, open-label, multi-center, randomized, non-inferiority trial aimed to enroll 1908 patients from ≥ 40 interventional cardiology centers in China to evaluate the non-inferiority of an antiplatelet regimen consisting of Aspirin plus Ticagrelor for one month, followed by five months Ticagrelor monotherapy, and then Aspirin monotherapy for six months (Experimental group) compared to the conventional treatment of Aspirin plus Ticagrelor for 12 months (Reference group) in patients with acute coronary syndrome (ACS) who have undergone percutaneous coronary intervention (PCI) using paclitaxel-coated balloons (DCB) exclusively...
January 20, 2024: BMC Cardiovascular Disorders
https://read.qxmd.com/read/38242567/de-escalation-of-dual-antiplatelet-therapy-for-patients-with-acute-coronary-syndrome-after-percutaneous-coronary-intervention-a-systematic-review-and-network-meta-analysis
#31
JOURNAL ARTICLE
Ovidio De Filippo, Francesco Piroli, Francesco Bruno, Pier Paolo Bocchino, Andrea Saglietto, Luca Franchin, Filippo Angelini, Guglielmo Gallone, Giulia Rizzello, Mahmood Ahmad, Mauro Gasparini, Saurav Chatterjee, Gaetano Maria De Ferrari, Fabrizio D'Ascenzo
OBJECTIVES: To compare dual antiplatelet therapy (DAPT) de-escalation with five alternative DAPT strategies in patients with acute coronary syndrome (ACS) undergoing percutaneous coronary intervention (PCI). DESIGN: We conducted a systematic review and network meta-analysis (NMA). Parallel-arm randomised controlled trials (RCTs) comparing DAPT strategies were included and arms of interest were compared via NMA. Partial ranking of each identified arm and for each investigated endpoint was also performed...
January 19, 2024: BMJ Evidence-Based Medicine
https://read.qxmd.com/read/38236518/spontaneous-coronary-artery-dissection-scad-from-an-interventionalist-perspective
#32
REVIEW
Nichole Brunton, Patricia J M Best, Kimberly A Skelding, Emily E Cendrowski
PURPOSE OF REVIEW: Spontaneous coronary artery dissection (SCAD) is an increasingly recognized cause of acute coronary syndrome (ACS), particularly among women < 50 years of age. Here, we aim to review the pathogenesis of SCAD, discuss SCAD as an initial manifestation of systemic arterial disease, and highlight invasive strategies as well as unique challenges in the care of women with SCAD. RECENT FINDINGS: A paradigm shift has occurred in the care of SCAD patients in the past decade as recommendations for conservative management have become widespread...
January 18, 2024: Current Cardiology Reports
https://read.qxmd.com/read/38224254/clinical-characteristics-and-outcomes-of-patients-requiring-prolonged-mechanical-circulatory-support-after-high-risk-percutaneous-coronary-intervention
#33
JOURNAL ARTICLE
Sugi Min, Mir Babar Basir, Alejandro Lemor, Zhipeng Zhou, Arsalan Abu-Much, Björn Redfors, Julia B Thompson, Alexander G Truesdell, Aditya S Bharadwaj, Yanru Li, Amir Kaki, Brigitta C Brott, David H Wohns, Perwaiz M Meraj, Ramesh Daggubati, Cindy L Grines, William W O'Neill, Jeffrey W Moses
BACKGROUND: There are limited data on the clinical characteristics and outcomes of patients who require prolonged mechanical circulatory support (MCS) after Impella-supported high-risk percutaneous coronary intervention (HR-PCI). AIMS: The aim of this study is to describe the contemporary clinical characteristics, outcomes, and predictors associated with prolonged MCS support after assisted HR-PCI. METHODS: Patients enrolled in the prospective, multicentre, clinical endpoint-adjudicated PROTECT III study who had undergone HR-PCI using Impella were evaluated...
January 15, 2024: EuroIntervention
https://read.qxmd.com/read/38214300/association-of-periprocedural-inflammatory-activation-with-increased-risk-for-early-coronary-stent-thrombosis
#34
JOURNAL ARTICLE
Konstantin A Krychtiuk, Konstantin Bräu, Stephanie Schauer, Alexander Sator, Lukas Galli, Andreas Baierl, Christian Hengstenberg, Clemens Gangl, Irene M Lang, Christian Roth, Rudolf Berger, Walter S Speidl
BACKGROUND: Stent thrombosis is a rare but deleterious event. Routine coronary angiography with percutaneous coronary intervention (PCI) is often deferred in the presence of laboratory markers of acute inflammation to prevent complications. The aim of this study was to investigate whether an acute inflammatory state is associated with an increased risk of early stent thrombosis. METHODS AND RESULTS: Within a prospective single-center registry, the association between preprocedural acute inflammatory activation, defined as C-reactive protein plasma levels >50 mg/L or a leukocyte count >12 g/L, and occurrence of early (≤30 days) stent thrombosis was evaluated...
January 12, 2024: Journal of the American Heart Association
https://read.qxmd.com/read/38214256/percutaneous-coronary-interventions-using-a-ridaforolimus-eluting-stent-in-patients-at-high-bleeding-risk
#35
JOURNAL ARTICLE
Ran Kornowski, Maayan Konigstein, Michael Jonas, Abid Assali, Hana Vaknin-Assa, Amit Segev, Haim Danenberg, Majdi Halabi, Ariel Roguin, Arthur Kerner, Eli Lev, Grigoris V Karamasis, Thomas W Johnson, Richard Anderson, Jonathan Blaxill, Sachin Jadhav, Stephen Hoole, Guy Witberg, Melek Ozgu Issever, Ori Ben-Yehuda, Andreas Baumbach
BACKGROUND: Patients treated with percutaneous coronary intervention are often considered to be at a high bleeding risk (HBR). Drug-eluting stents have been shown to be superior to bare-metal stents in patients with HBR, even when patients were given abbreviated periods of dual antiplatelet therapy (DAPT). Short DAPT has not been evaluated with the EluNIR ridaforolimus-eluting stent. The aim of this study was to evaluate the safety and efficacy of a shortened period of DAPT following implantation of the ridaforolimus-eluting stent in patients with HBR...
January 12, 2024: Journal of the American Heart Association
https://read.qxmd.com/read/38211886/outcomes-of-drug-eluting-balloons-for-in-stent-restenosis-large-cohort-analysis-and-single-center-clinical-experience
#36
JOURNAL ARTICLE
Mark Kheifets, Ori Rahat, Tamir Bental, Amos Levi, Hana Vaknin-Assa, Gabriel Greenberg, Pablo Codner, Guy Witberg, Ran Kornowski, Leor Perl
BACKGROUND: The use of drug eluting balloons (DEB) remains clinically relevant in the contemporary era of drug eluting stents percutaneous coronary interventions (DES-PCI), especially in the setting of in stent restenosis (ISR). Our goal was to assess the outcomes of ISR patients in a large prospective registry. METHODS: 2329 consecutive patients with ISR-PCI (675 using DEB and 1654 with DES) were treated in our medical center between 2010-2021. Clinical endpoints included mortality and major adverse cardiac events at 1 year...
January 9, 2024: Canadian Journal of Cardiology
https://read.qxmd.com/read/38211674/a-comprehensive-guide-on-the-optimal-timing-of-pci-in-the-setting-of-acute-coronary-syndrome-an-updated-meta-analysis
#37
JOURNAL ARTICLE
Ahmed Abdelaziz, Hanaa Elsayed, Karim Atta, Ahmed Mechi, Hallas Kadhim, Aya Moustafa Aboutaleb, Ahmed Elaraby, Mohamed Hatem Ellabban, Mahmoud Eid, Hadeer Elsaeed AboElfarh, Rahma AbdElfattah Ibrahim, Emad Addin Zawaneh, Mahmoud Ezzat, Mohamed Abdelaziz, Abdelrahman Hafez, Ahmed Mahmoud, Hazem S Ghaith, Mustafa Suppah
BACKGROUND: Invasive revascularization is recommended for cohorts of patients with ST-elevation myocardial infarction (STEMI) and non-ST-elevation acute coronary syndrome (NSTE-ACS). However, the optimal timing of invasive revascularization is still controversial and no defined consensus is established. We aim to give a comprehensive appraisal on the optimal timing of invasive strategy in the heterogenous population of ACS. METHODS: Relevant studies were assessed through PubMed, Scopus, Web of science, and Cochrane Library from inception until April 2023...
January 9, 2024: International Journal of Cardiology
https://read.qxmd.com/read/38188320/a-rare-case-of-type-2-kounis-syndrome-secondary-to-iodinated-contrast
#38
Farrah Shahrzad Nasrollahi, Lauren Friend, Keshav Patel, Sean Behan, Khalil Ibrahim
UNLABELLED: Immune-mediated acute coronary syndrome, also known as Kounis syndrome (KS), is an underrecognized and challenging diagnosis. In this case report, we present a case of cardiac arrest secondary to iodinated contrast allergy requiring emergent cardiac catheterization and hemodynamic support secondary to type 2 KS. KS necessitates a high index of clinical suspicion by the treating physician in order to address both the hypersensitivity reaction and its cardiac implications. LEARNING OBJECTIVES: Kounis syndrome (KS) is a clinically distinct entity from anaphylaxis; managing KS in the same way as anaphylaxis can worsen cardiac demand and ischemia...
January 2024: Journal of Cardiology Cases
https://read.qxmd.com/read/38173904/quo-vadis-cardiac-rehabilitation-the-role-of-comprehensive-cardiac-rehabilitation-in-modern-cardiology
#39
EDITORIAL
Nenad Lakušić, Ivana Sopek Merkaš
In accordance with the guidelines established by prominent European and global cardiology associations, comprehensive cardiac rehabilitation (CR) stands as an officially endorsed and highly recommended therapeutic approach (class I recommendations; level of evidence A) for a diverse spectrum of cardiac patients. Nevertheless, it is a cause for concern to observe that fewer than 50% of eligible patients are being effectively referred for CR, whether in an outpatient or inpatient setting. Concurrently, studies reveal that a substantial proportion of individuals with atherosclerotic cardiovascular disease maintain unhealthy lifestyles and exhibit suboptimal management of modifiable cardiovascular risk factors, including hypertension, lipid levels, and diabetes...
December 26, 2023: World Journal of Cardiology
https://read.qxmd.com/read/38165113/procedural-and-one-year-outcomes-of-robotic-assisted-versus-manual-percutaneous-coronary-intervention
#40
JOURNAL ARTICLE
Benjamin Bay, Luisa M Kiwus, Alina Goßling, Lukas Koester, Christopher Blaum, Benedikt Schrage, Peter Clemmensen, Stefan Blankenberg, Christoph Waldeyer, Moritz Seiffert, Fabian J Brunner
BACKGROUND: Robotic-assisted percutaneous coronary intervention (rPCI) has proven to be feasible and safe. Comparative analyses of rPCI versus manual PCI (mPCI) are scarce. AIMS: We aimed to investigate procedural aspects and outcomes of rPCI using the second-generation CorPath GRX Vascular Robotic System compared with mPCI in patients with chronic coronary syndrome and non-ST-segment elevation myocardial infarction acute coronary syndrome. METHODS: From January to April 2021, 70 patients underwent rPCI at the University Heart & Vascular Center Hamburg-Eppendorf and were recruited into the INTERCATH study...
January 1, 2024: EuroIntervention
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