keyword
Keywords Dementia, behaviour and psycho...

Dementia, behaviour and psychological symptoms of dementia, aggression, cognition

https://read.qxmd.com/read/37837249/nonpharmacological-nursing-interventions-for-behavioural-and-psychological-symptoms-of-dementia-in-acute-and-subacute-settings-a-systematic-review
#1
REVIEW
Sahaya Jesto, Julie Considine, Maryann Street
BACKGROUND: Behavioural and psychological symptoms of dementia are a group of non-cognitive symptoms such as agitation, physical aggression, depression, sexual disinhibition and psychosis. Therapeutic approaches vary because of the multifactorial and complex symptomology. The researchers of this study aimed to systematically review the nonpharmacological interventions for BPSD used by nurses in acute and subacute hospital settings. DESIGN: The PRISMA guidelines guided this systematic review...
October 13, 2023: International Journal of Nursing Practice
https://read.qxmd.com/read/37182008/the-importance-of-person-centered-approaches-to-managing-behavioral-and-psychological-symptoms-of-dementia-a-case-report
#2
Kayla S Murphy, David M Atkinson, Jamie Starks
Behavioral and psychological symptoms of dementia (BPSD) are common and associated with increased morbidity and mortality in dementia. In this report, we describe a patient with severe BPSD who was effectively managed with a variety of non-pharmacologic strategies. A 70-year-old Navy veteran and retired commercial flooring business owner with a history of dementia was admitted to the hospital with aggressive behavior. He was no longer manageable by his family. He required intermittent use of restraints and multiple antipsychotics during hospitalization...
April 2023: Curēus
https://read.qxmd.com/read/37042595/the-program-of-the-complex-differentiated-medical-and-psychological-rehabilitation-of-the-patients-with-suicidal-behaviour-in-dementia
#3
JOURNAL ARTICLE
I Mudrenko, O Kolenko, L Kiptenko, V Lychko, D Sotnikov, O Yurchenko
The conceptual model of rehabilitation and suicidal behaviour prevention in dementia, considering the multiple components, is presented in the article. The developed program of the complex differentiated medical and psychological rehabilitation and suicidal behaviour prevention (MPRS BP) in patients with dementia is aimed at the preventive measures of the suicidal behaviour (SB) through the depressive symptoms reduction, patient's mind and cognitive status stabilization, self-aggression decreases, social functioning and independence increase in patients with dementia...
February 2023: Georgian Medical News
https://read.qxmd.com/read/36496108/neuropharmacological-effect-of-risperidone-from-chemistry-to-medicine
#4
REVIEW
Asif Ahmed Bhat, Gaurav Gupta, Obaid Afzal, Imran Kazmi, Fahad A Al-Abbasi, Abdulmalik Saleh Alfawaz Altamimi, Waleed Hassan Almalki, Sami I Alzarea, Sachin Kumar Singh, Kamal Dua
As the second-oldest atypical antipsychotic, risperidone has a long history of off-label usage for treating behavioural and psychological signs and symptoms of dementia (BPSD), such as agitation, aggressiveness, and psychosis. Risperidone has been shown in several trials to have a statistically significant benefit when used in a therapeutic context. Several lines of evidence suggest a possible role of risperidone via the antagonistic effect of Dopamine D2 and 5HT-receptor in different neurological diseases like cognitive dysfunction of schizophrenia, neuroinflammation, Huntington's disease, and sleep cycle management...
December 7, 2022: Chemico-biological Interactions
https://read.qxmd.com/read/36010679/cognitive-decline-and-bpsd-are-concomitant-with-autophagic-and-synaptic-deficits-associated-with-g9a-alterations-in-aged-samp8-mice
#5
JOURNAL ARTICLE
Foteini Vasilopoulou, Aina Bellver-Sanchis, Júlia Companys-Alemany, Júlia Jarne-Ferrer, Alba Irisarri, Verónica Palomera-Ávalos, Celia Gonzalez-Castillo, Daniel Ortuño-Sahagún, Coral Sanfeliu, Mercè Pallàs, Christian Griñán-Ferré
Behavioural and psychological symptoms of dementia (BPSD) are presented in 95% of Alzheimer's Disease (AD) patients and are also associated with neurotrophin deficits. The molecular mechanisms leading to age-related diseases are still unclear; however, emerging evidence has suggested that epigenetic modulation is a key pathophysiological basis of ageing and neurodegeneration. In particular, it has been suggested that G9a methyltransferase and its repressive histone mark (H3K9me2) are important in shaping learning and memory by modulating autophagic activity and synaptic plasticity...
August 21, 2022: Cells
https://read.qxmd.com/read/35363380/algorithm-based-pain-management-for-people-with-dementia-in-nursing-homes
#6
REVIEW
Christina Manietta, Valérie Labonté, Rüdiger Thiesemann, Erika G Sirsch, Ralph Möhler
BACKGROUND: People with dementia in nursing homes often experience pain, but often do not receive adequate pain therapy. The experience of pain has a significant impact on quality of life in people with dementia, and is associated with negative health outcomes. Untreated pain is also considered to be one of the causes of challenging behaviour, such as agitation or aggression, in this population. One approach to reducing pain in people with dementia in nursing homes is an algorithm-based pain management strategy, i...
April 1, 2022: Cochrane Database of Systematic Reviews
https://read.qxmd.com/read/34971243/changed-behaviours-associated-with-cognitive-decline-views-of-people-living-with-dementia-families-and-healthcare-professionals
#7
JOURNAL ARTICLE
Claire V Burley, Lynnette Chenoweth, Anne-Nicole S Casey, Henry Brodaty
Changed behaviours associated with cognitive decline (also known as neuropsychiatric symptoms (NPS), behavioural and psychological symptoms of dementia (BPSD), and responsive behaviours) occur in up to 90-percent of people living with dementia (PLWD). They strongly correlate with functional and cognitive impairment and contribute to approximately 30-percent of overall dementia costs. Decisions regarding care and strategies for changed behaviours are often determined by families and healthcare professionals and are not inclusive of PLWD...
December 2021: Alzheimer's & Dementia: the Journal of the Alzheimer's Association
https://read.qxmd.com/read/34553116/a-delicate-balance-psychotropic-polypharmacy-and-anti-cholinergic-use-are-correlated-with-fall-incidence-in-australian-inpatients-with-dementia
#8
JOURNAL ARTICLE
Samuel X Tan, Sarah C Cameron, Lit Min Sam, Hugh Eigeland, Karen Hay, Eamonn Eeles, Kannan Natarajan
BACKGROUND: Persons with dementia commonly experience a range of behavioural and psychological symptoms, including agitation, aggression, perceptual disturbances, and depression. While psychotropic medications are regularly prescribed to mitigate these symptoms, these agents also carry a broad adverse effect profile. This study aimed to characterize psychotropic medication use in patients with dementia, as well as identify prescribing factors associated with falls in this cohort. METHODS: This retrospective study collected longitudinal demographic and medication data from all patients admitted to a neuro-cognitive unit at an Australian metropolitan hospital over a 2-year period...
September 2021: Aging medicine
https://read.qxmd.com/read/33881215/behavioural-disorders-in-alzheimer-s-disease-the-descriptive-and-predictive-role-of-brain-18-f-fluorodesoxyglucose-positron-emission-tomography
#9
JOURNAL ARTICLE
Pietro Cappelletto, Cristina Polito, Valentina Berti, Gemma Lombardi, Giulia Lucidi, Valentina Bessi, Sandro Sorbi, Camilla Ferrari
BACKGROUND: Alzheimer's disease (AD) has a high incidence in the elderly. Besides cognitive disorders, patients may also develop behavioural and psychological symptoms of dementia (BPSD), which can be particularly disabling for patients and families. BPSD encompass a wide range of symptoms, among which psychotic symptoms and disruptive behaviours often prompt the first related hospitalization and request for family support. The aetiological mechanism of BPSD has not yet been clarified, and no predictive or risk factors have been identified...
July 2021: Psychogeriatrics: the Official Journal of the Japanese Psychogeriatric Society
https://read.qxmd.com/read/33663416/behavioural-and-psychological-symptoms-of-dementia-in-patients-with-alzheimer-s-disease-and-family-caregiver-burden-a-path-analysis
#10
JOURNAL ARTICLE
Bokyoung Kim, Gie Ok Noh, Kyunghee Kim
BACKGROUND: Studies reported the relationship between behavioural and psychological symptoms of dementia (BPSD), cognitive function, caregiver burden, and therapeutic effects. However, the causal relationship between BPSD in community-dwelling patients with Alzheimer's disease (AD) and caregiver burden is yet to be established. This study aimed to classify BPSD in patients with AD and identify the relationship between BPSD and the factors affecting family caregiver burden. METHODS: Path analysis was conducted at a neurology outpatient clinic of a tertiary general hospital in South Korea...
March 5, 2021: BMC Geriatrics
https://read.qxmd.com/read/32239593/post-traumatic-stress-disorder-mistaken-for-behavioural-and-psychological-symptoms-of-dementia-case-series-and-recommendations-of-care
#11
REVIEW
Marie-Andrée Bruneau, Philippe Desmarais, Klara Pokrzywko
In late life, traumas may act cumulatively to exacerbate vulnerability to post-traumatic stress disorder (PTSD). PTSD is also a risk factor for cognitive decline. Major neurocognitive disorder (MND) can be associated with worsening of already controlled PTSD symptoms, late-life resurgence or de novo emergence. Misidentifying PTSD symptoms in MND can have negative consequences for the patient and families. We review the literature pertaining to PTSD and dementia and describe five cases referred for consultation in geriatric psychiatry initially for behavioural and psychological symptoms of dementia (BPSD), which were eventually diagnosed and treated as PTSD in MND subjects...
September 2020: Psychogeriatrics: the Official Journal of the Japanese Psychogeriatric Society
https://read.qxmd.com/read/32070692/behavioural-and-psychological-symptoms-of-dementia-in-mouse-models-of-alzheimer-s-disease-related-pathology
#12
REVIEW
Filip Kosel, Jessica M S Pelley, Tamara B Franklin
Transgenic mouse models have been used extensively to model the cognitive impairments arising from Alzheimer's disease (AD)-related pathology. However, less is known about the relationship between AD-related pathology and the behavioural and psychological symptoms of dementia (BPSD) commonly presented by patients. This review discusses the BPSD-like behaviours recapitulated by several mouse models of AD-related pathology, including the APP/PS1, Tg2576, 3xTg-AD, 5xFAD, and APP23 models. Current evidence suggests that social withdrawal and depressive-like behaviours increase with progressive neuropathology, and increased aggression and sleep-wake disturbances are present even at early stages; however, there is no clear evidence to support increased anxiety-like behaviours, agitation (hyperactivity), or general apathy...
May 2020: Neuroscience and Biobehavioral Reviews
https://read.qxmd.com/read/30457967/non-pharmacological-interventions-for-agitation-aggressive-behaviour-in-patients-with-dementia-a-randomized-controlled-crossover-trial
#13
RANDOMIZED CONTROLLED TRIAL
T-D Dimitriou, Eleni Verykouki, John Papatriantafyllou, A Konsta, D Kazis, M Tsolaki
Agitation/aggressive behaviour is a common behavioural and psychological symptom in people with dementia (PwD), occurring with a frequency of between 13-50.4% according to recent studies, and the rate increases as the severity of cognitive decline increases. The burden on caregivers is considerable. This trial is a randomized controlled crossover trial conducted in Greece. The following measures were used: the Mini-Mental State Examination, Addenbrooke's Cognitive Examination Revised, Geriatric Depression Scale, Functional Rating Scale for Symptoms in Dementia and Neuropsychiatric Inventory...
July 2018: Functional Neurology
https://read.qxmd.com/read/29605970/withdrawal-versus-continuation-of-long-term-antipsychotic-drug-use-for-behavioural-and-psychological-symptoms-in-older-people-with-dementia
#14
REVIEW
Ellen Van Leeuwen, Mirko Petrovic, Mieke L van Driel, An Im De Sutter, Robert Vander Stichele, Tom Declercq, Thierry Christiaens
BACKGROUND: Antipsychotic agents are often used to treat neuropsychiatric symptoms (NPS) in people with dementia although there is uncertainty about the effectiveness of their long-term use for this indication and concern that they may cause harm, including higher mortality. When behavioural strategies have failed and treatment with antipsychotic drugs is instituted, regular attempts to withdraw them have been recommended in guidelines. Physicians, nurses and families of older people with dementia may be reluctant to stop antipsychotics, fearing deterioration of NPS...
March 30, 2018: Cochrane Database of Systematic Reviews
https://read.qxmd.com/read/29521195/neuropharmacological-properties-of-the-essential-oil-of-bergamot-for-the-clinical-management-of-pain-related-bpsds
#15
REVIEW
Damiana Scuteri, Laura Rombolá, Laura Tridico, Hirokazu Mizoguchi, Chizuko Watanabe, Tsukasa Sakurada, Shinobu Sakurada, Maria T Corasaniti, Giacinto Bagetta, Luigi A Morrone
BACKGROUND: Alzheimer's Disease (AD) accounts for approximately 50% of all cases of dementia and, in spite of the great effort for the development of disease-modifying drugs, a definitive treatment of cognitive impairment is not available yet. A perfect adherence to the current therapy of cognitive decline is needed for a better control of the disease and this is proven to reduce, though not completely abolish, the associated Behavioural and Psychological Symptoms of Dementia (BPSDs) from occurring...
2019: Current Medicinal Chemistry
https://read.qxmd.com/read/29305363/efficacy-and-safety-of-maintenance-electroconvulsive-therapy-for-sustaining-resolution-of-severe-aggression-in-a-major-neurocognitive-disorder
#16
JOURNAL ARTICLE
Melanie Isabella Selvadurai, Robyn Waxman, Omar Ghaffar, Ilan Fischler
We report a novel electroconvulsive therapy (ECT) regimen for sustaining the resolution of behavioural and psychological symptoms of dementia (BPSD) using alternating acute and maintenance ECT (M-ECT) trials. A 64-year-old man presenting with major neurocognitive disorder was admitted for acute behavioural disturbances and physical aggression. With few treatment options, the impact on patients' quality of life often supersedes cognitive symptoms and is a predictor of long-term institutionalisation. Recent studies indicate that ECT may be an effective and safe way to address BPSD...
January 5, 2018: BMJ Case Reports
https://read.qxmd.com/read/27593707/what-is-the-therapeutic-value-of-antidepressants-in-dementia-a-narrative-review
#17
REVIEW
Nicolas Farina, Lucy Morrell, Sube Banerjee
OBJECTIVES: Antidepressants are commonly used in dementia. Depression is a frequent and important co-morbidity in dementia, and antidepressants are often used to treat depression and more widely. However, there are questions about their utility in depression in dementia and other behavioural and psychological symptoms of dementia. The aim of this narrative review is to summarize the evidence on whether there is therapeutic value in prescribing antidepressants to people with dementia. METHODS: A PubMed search was performed to identify randomized controlled trials that prescribed antidepressants to people with dementia, either in the treatment of behavioural and psychological symptoms of dementia (depression, anxiety, agitation/aggression, psychosis and apathy) or for secondary outcomes (quality of life, carer burden, activities of daily living, cognition, clinical severity and adverse events)...
January 2017: International Journal of Geriatric Psychiatry
https://read.qxmd.com/read/25351844/the-prevalence-and-burden-of-behavioural-and-psychological-symptoms-of-dementia-in-rural-tanzania
#18
JOURNAL ARTICLE
S-M Paddick, A Kisoli, A Longdon, C Dotchin, W K Gray, P Chaote, A Teodorczuk, R Walker
OBJECTIVES: Behavioural and psychological symptoms (BPS) in dementia are common in high-income countries, but there are few data from sub-Saharan Africa. Our aim was to estimate the prevalence and pattern of BPS and associated caregiver distress in rural Tanzania. METHODS: Prevalent cases of dementia (aged 70 and over) were identified during a community-based door-to-door study in six rural villages in Tanzania. Following cognitive screening, a stratified sample (over-sampled for people with dementia) of cases underwent a detailed clinical assessment including the brief 12 item neuropsychiatric inventory (NPI-Q), which assesses BPS and associated caregiver distress over the preceding 30 days...
August 2015: International Journal of Geriatric Psychiatry
https://read.qxmd.com/read/25016769/-neurobehavioral-manifestation-in-early-period-of-alzheimer-disease-and-vascular-dementia
#19
COMPARATIVE STUDY
Mariola Bidzan, Leszek Bidzan
INTRODUCTION: AD and VD are preceded by a preclinical stage. Small but tangible cognitive impairments sometimes occur many years before the onset and diagnosis ofdementia. The ongoing degenerative process can be conductive to behavioural and psychological symptoms. AIM: The aim of the study was to investigate the rates of neurobehavioral symptoms in the preclinical stages of AD and VD. METHODS: Two hundred and ninety one residents of nursery homes were included in the study...
2014: Psychiatria Polska
https://read.qxmd.com/read/24945337/risperidone-in-the-treatment-of-behavioural-and-psychological-symptoms-of-dementia-in-patients-diagnosed-with-vascular-or-mixed-type-dementia
#20
JOURNAL ARTICLE
Alfonso J Cruz-Jentoft, José-Antonio Burón, Jesús I Diago, Ricardo Gallego
Objective Studies have found that the atypical antipsychotic drug, risperidone, reduces non-cognitive symptoms, such as aggression, agitation, and psychosis, in patients with Alzheimer's disease. This study assessed whether these effects extend to patients with vascular or mixed-type dementia. Methods In this multicentre, open-label, prospective study, 75 elderly patients with vascular or mixed-type dementia and concomitant behavioural and psychological symptoms were treated with risperidone for up to 6 months...
2005: International Journal of Psychiatry in Clinical Practice
keyword
keyword
38569
1
2
Fetch more papers »
Fetching more papers... Fetching...
Remove bar
Read by QxMD icon Read
×

Save your favorite articles in one place with a free QxMD account.

×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"

We want to hear from doctors like you!

Take a second to answer a survey question.