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https://www.readbyqxmd.com/read/28410665/impact-of-dietary-precursor-ala-versus-preformed-dha-on-fatty-acid-profiles-of-eggs-liver-and-adipose-tissue-and-expression-of-genes-associated-with-hepatic-lipid-metabolism-in-laying-hens
#1
M Neijat, P Eck, J D House
Dietary omega-3 polyunsaturated fatty acids (n-3 PUFA), including alpha-linolenic acid (ALA) and preformed longer chain PUFA (LCPUFA, particularly docosahexaenoic acid, DHA) differ in their egg LCPUFA enrichment efficiency. However, mechanisms leading to these differences are unclear. To this end, omega-3 PUFA contents in different lipid classes, including triacylglycerol (TAG) and total phospholipid (PL) in yolk, liver and adipose, as well as the expression of key hepatic enzymes in lipid metabolism were evaluated in laying hens in response to changes in dietary supply...
April 2017: Prostaglandins, Leukotrienes, and Essential Fatty Acids
https://www.readbyqxmd.com/read/28407657/the-effects-of-omega-3-fatty-acids-and-vitamin-e-co-supplementation-on-indices-of-insulin-resistance-and-hormonal-parameters-in-patients-with-polycystic-ovary-syndrome-a-randomized-double-blind-placebo-controlled-trial
#2
Faraneh Afshar Ebrahimi, Mansooreh Samimi, Fatemeh Foroozanfard, Mehri Jamilian, Hossein Akbari, Elham Rahmani, Shahnaz Ahmadi, Mohsen Taghizadeh, Mohammad Reza Memarzadeh, Zatollah Asemi
This study was conducted to determine the effects of omega-3 fatty acids and vitamin E co-supplementation on indices of insulin resistance and hormonal parameters in women with polycystic ovary syndrome (PCOS). This randomized double-blind, placebo-controlled trial was done on 68 women diagnosed with PCOS according to the Rotterdam criteria aged 18-40 years old. Participants were randomly assigned into 2 groups to receive either 1 000 mg omega-3 fatty acids from flaxseed oil containing 400 mg α-Linolenic acid plus 400 IU vitamin E supplements (n=34) or placebo (n=34) for 12 weeks...
April 13, 2017: Experimental and Clinical Endocrinology & Diabetes
https://www.readbyqxmd.com/read/28406725/flaxseed-and-buckwheat-supplemented-diets-altered-enterobacteriaceae-diversity-and-prevalence-in-the-cecum-and-feces-of-obese-mice
#3
Margaret Pulkrabek, Yeong Rhee, Penelope Gibbs, Clifford Hall
Dietary intake may cause variable bacterial prevalence in the gastrointestinal tract. The objective of this research was to determine the prevalence of Enterobacteriaceae in the cecum and feces and its relationship to weight changes following flaxseed-, health-promoting compounds of flaxseed-, or buckwheat-supplemented diets. Seventy-two C57BL/6J male mice were randomly assigned to a diet group and fed for 8 weeks: high fat (45% kcal fat); 10% whole flaxseed (45% kcal fat); 6% defatted flaxseed (45% kcal fat); 4% flaxseed oil (45% kcal fat); 10% buckwheat (45% kcal fat); and low fat (16% kcal fat) diet groups...
April 13, 2017: Journal of Dietary Supplements
https://www.readbyqxmd.com/read/28399949/in-ovo-exposure-to-omega-3-fatty-acids-does-not-enhance-omega-3-long-chain-polyunsaturated-fatty-acid-metabolism-in-broiler-chickens
#4
K Kanakri, J Carragher, B Muhlhausler, R Hughes, R Gibson
The content of omega-3 long-chain polyunsaturated fatty acids (n-3 LCPUFA) in chicken meat can be boosted by feeding broilers a diet containing α-linolenic acid (ALA, from flaxseed oil), some of which is converted by hepatic enzymes to n-3 LCPUFA. However, most of the accumulated n-3 polyunsaturated fatty acid (PUFA) in meat tissues is still in the form of ALA. Despite this, the levels of chicken diets are being enhanced by the inclusion of vegetable and marine sources of omega-3 fats. This study investigated whether the capacity of chicken for n-3 LCPUFA accumulation could be enhanced or inhibited by exposure to an increased supply of ALA or n-3 LCPUFA in ovo...
April 12, 2017: Journal of Developmental Origins of Health and Disease
https://www.readbyqxmd.com/read/28393603/improving-functional-properties-of-pea-protein-isolate-for-microencapsulation-of-flaxseed-oil
#5
Poonam R Bajaj, Kanishka Bhunia, Leslie Kleiner, Helen S Joyner Melito, Denise Smith, Girish Ganjyal, Shyam S Sablani
Unhydrolyzed pea protein (UN) forms very viscous emulsions when used at higher concentrations. To overcome this, UN was hydrolyzed using enzymes Alcalase, Flavourzyme, Neutrase, Alcalase-Flavourzyme and Neutrase-Flavourzyme at 50°C for 0 min, 30 min, 60 min and 120 min to form hydrolyzed proteins A, F, N, AF and NF, respectively. All hydrolyzed proteins had lower apparent viscosity and higher solubility than UN. Foaming capacity of A was highest, followed by NF, N, and AF. Hydrolyzed proteins N60, A60, NF60 and AF60 were prepared by hydrolyzing UN for 60 min and used further for microencapsulation...
April 10, 2017: Journal of Microencapsulation
https://www.readbyqxmd.com/read/28359208/omega-3-fortified-lipid-based-nutrient-supplement
#6
Shashank Gaur, Elizabeth M Sloffer, Ankur Ojha, Falguni Patra, Dharmendra Shukla, Nicki J Engeseth, Pramthesh R Patel, Juan E Andrade
BACKGROUND: Incorporation of omega-3 polyunsaturated fatty acid (PUFA) sources to lipid-based nutrition supplement (LNS) formulations for undernourished populations presents a challenge due to reduced shelf life and poor consumer acceptability. OBJECTIVE: To systematically develop an omega-3-fortified LNS formulation, using flaxseed oil (FO), by optimizing its processing stability and evaluating its sensory acceptance. METHODS: LNS formulations were formulated to yield approximately 452 kcal, 13...
January 1, 2017: Food and Nutrition Bulletin
https://www.readbyqxmd.com/read/28342967/the-effects-of-omega-3-fatty-acids-and-vitamin-e-co-supplementation-on-clinical-and-metabolic-status-in-patients-with-parkinson-s-disease-a-randomized-double-blind-placebo-controlled-trial
#7
Mohsen Taghizadeh, Omid Reza Tamtaji, Ehsan Dadgostar, Reza Daneshvar Kakhaki, Fereshteh Bahmani, Javad Abolhassani, Mohammad Hossein Aarabi, Ebrahim Kouchaki, Mohammad Reza Memarzadeh, Zatollah Asemi
The current research was performed to evaluate the effects of omega-3 fatty acids and vitamin E co-supplementation on clinical signs and metabolic status in people with Parkinson's disease (PD). This randomized double-blind placebo-controlled clinical trial was conducted in 60 patients with PD. Participants were randomly assigned into two groups to receive either 1000 mg omega-3 fatty acids from flaxseed oil plus 400 IU vitamin E supplements (n = 30) or placebo (n = 30) for 12 weeks. Unified Parkinson's disease rating stage (UPDRS) were recorded at baseline and the after 3-month intervention...
March 22, 2017: Neurochemistry International
https://www.readbyqxmd.com/read/28335388/a-combination-of-flaxseed-oil-and-astaxanthin-improves-hepatic-lipid-accumulation-and-reduces-oxidative-stress-in-high-fat-diet-fed-rats
#8
Jiqu Xu, Shuang Rong, Hui Gao, Chang Chen, Wei Yang, Qianchun Deng, Qingde Huang, Lingyun Xiao, Fenghong Huang
Hepatic lipid accumulation and oxidative stress are crucial pathophysiological mechanisms for non-alcoholic fatty liver disease (NAFLD). Thus, we examined the effect of a combination of flaxseed oil (FO) and astaxanthin (ASX) on hepatic lipid accumulation and oxidative stress in rats fed a high-fat diet. ASX was dissolved in flaxseed oil (1 g/kg; FO + ASX). Animals were fed diets containing 20% fat, where the source was lard, or 75% lard and 25% FO + ASX, or 50% lard and 50% FO + ASX, or FO + ASX, for 10 weeks...
March 13, 2017: Nutrients
https://www.readbyqxmd.com/read/28320208/fresh-cheese-as-a-vehicle-for-polyunsaturated-fatty-acids-integration-effect-on-physico-chemical-microbiological-and-sensory-characteristics
#9
Barbara Dal Bello, Luisa Torri, Maria Piochi, Marta Bertolino, Giuseppe Zeppa
Five different vegetable oils were used in the production of fresh cheese to increase the concentration of polyunsaturated fatty acids (PUFAs), particularly α-linolenic acid (ALA), the most important omega-3 fatty acid of vegetable origin. Physico-chemical and microbiological characteristics of functionalized cheeses were evaluated after 1 and 3 days of ripening at 4 °C while the consumer appreciation was evaluated in the final product at 3 days of ripening. After 3 days, the cheeses with Camelina sativa and Echium plantagineum oils added exhibited the highest retention of PUFAs (mostly ALA) compared to those with flaxseed, raspberry and blackcurrant oils...
March 20, 2017: International Journal of Food Sciences and Nutrition
https://www.readbyqxmd.com/read/28284063/soybean-polar-lipids-differently-impact-adipose-tissue-inflammation-and-the-endotoxin-transporters-lbp-and-scd14-in-flaxseed-vs-palm-oil-rich-diets
#10
Manon Lecomte, Leslie Couëdelo, Emmanuelle Meugnier, Emmanuelle Loizon, Pascale Plaisancié, Annie Durand, Alain Géloën, Florent Joffre, Carole Vaysse, Marie-Caroline Michalski, Fabienne Laugerette
Obesity and type 2 diabetes are nutritional pathologies, characterized by a subclinical inflammatory state. Endotoxins are now well recognized as an important factor implicated in the onset and maintain of this inflammatory state during fat digestion in high-fat diet. As a preventive strategy, lipid formulation could be optimized to limit these phenomena, notably regarding fatty acid profile and PL emulsifier content. Little is known about soybean polar lipid (SPL) consumption associated to oils rich in saturated FA vs...
February 21, 2017: Journal of Nutritional Biochemistry
https://www.readbyqxmd.com/read/28277795/a-reduced-cost-strategy-for-enriching-chicken-meat-with-omega-3-long-chain-polyunsaturated-fatty-acids-using-dietary-flaxseed-oil
#11
K Kanakri, J Carragher, R Hughes, B Muhlhausler, R Gibson
1. This study aimed to determine the minimal duration required for feeding male broilers (Cobb 500) with a flaxseed oil diet while still retaining long chain omega-3 polyunsaturated fatty acid (n-3 LCPUFA) accumulation in the meat at a desirable level. 2. Three groups of broilers (60 each) were fed on a 3% flaxseed oil (high α-linolenic acid (ALA)) diet for either 6, 4 or 2 weeks prior to slaughter. During the remaining time they were maintained on a 3% macadamia oil (low ALA) diet. A fourth group (Control, n=60) was fed on a commercial diet for 6 weeks...
February 15, 2017: British Poultry Science
https://www.readbyqxmd.com/read/28250313/nutritional-evaluation-of-oleogel-made-from-micronutrient-rich-edible-oils
#12
Moumita Ghosh, Faruk Begg, Dipak K Bhattacharyya, Nilratan Bandyopadhya, Mahua Ghosh
The present study examined the nutritional properties of trans-free edible oleogels made from oil blends of rice bran and flaxseed in animal model. Oleogels were prepared by using mixture of palm stearin (PS) with cetyl laurate (CL) and palm stearin (PS) with cetyl caprylate (CC) as oleogelators. The oleogel samples were prepared with 15 weight % oleogelators (2:1 molar ratio of PS:CC or PS:CL) at 60°C with 1 hr constant stirring in blended oil. The prepared oleogel samples were subjected to DSC and XRD studies in order to evaluate their melting and crystal characteristics...
2017: Journal of Oleo Science
https://www.readbyqxmd.com/read/28242936/effect-of-flaxseed-oil-and-flour-on-sensory-physicochemical-and-fatty-acid-profile-of-the-fruit-yoghurt
#13
S Siva Kumar, B V Balasubramanyam, K Jayaraj Rao, P Heartwin Amala Dhas, B Surendra Nath
The objective of this study was to incorporate flaxseed oil, flaxseed flour and fruits for the preparation of fruit yoghurt and analysed for their sensory, physicochemical and fatty acid profile. Overall acceptability of sensory scores indicates that fruit yoghurt (20% fruit and sugar mixture) with incorporation of flaxseed oil up to 2% and flaxseed flour up to 1% in combination can be used for preparation of fruit yoghurt with acceptable sensory attributes. The scores drastically reduced for yoghurt samples wherein 2% flaxseed flour was incorporated...
February 2017: Journal of Food Science and Technology
https://www.readbyqxmd.com/read/28228158/flaxseed-oil-ameliorates-alcoholic-liver-disease-via-anti-inflammation-and-modulating-gut-microbiota-in-mice
#14
Xiaoxia Zhang, Hao Wang, Peipei Yin, Hang Fan, Liwei Sun, Yujun Liu
BACKGROUND: Alcoholic liver disease (ALD) represents a chronic wide-spectrum of liver injury caused by consistently excessive alcohol intake. Few satisfactory advances have been made in management of ALD. Thus, novel and more practical treatment options are urgently needed. Flaxseed oil (FO) is rich in α-linolenic acid (ALA), a plant-derived n-3 polyunsaturated fatty acids (PUFAs). However, the impact of dietary FO on chronic alcohol consumption remains unknown. METHODS: In this study, we assessed possible effects of dietary FO on attenuation of ALD and associated mechanisms in mice...
February 22, 2017: Lipids in Health and Disease
https://www.readbyqxmd.com/read/28209094/attenuation-of-arsenic-trioxide-induced-cardiotoxicity-through-flaxseed-oil-in-experimental-rats
#15
Mathews V Varghese, M Abhilash, Manju Alex, M V Sauganth Paul, A Prathapan, K G Raghu, R Harikumaran Nair
OBJECTIVES: Arsenic trioxide (As2O3) is a potent drug for acute promyelocytic leukaemia, but its clinical trials are allied with some serious adverse events mainly cardiac functional abnormalities. So the objective of our investigation is to identify the cardioprotective action of flaxseed oil (FSO), a natural compound against As2O3 induced cardiotoxicity. METHODS: Male wistar rats were treated with As2O3 (4 mg/kg) to induce cardiotoxicity. FSO (250 and 500 mg/kg) was given in combination with As2O3 for evaluating its cardioprotective efficacy...
February 17, 2017: Redox Report: Communications in Free Radical Research
https://www.readbyqxmd.com/read/28157307/lipidomic-analysis-of-oxidized-fatty-acids-in-plant-and-algae-oils
#16
Christine E Richardson, Marie Hennebelle, Yurika Otoki, Daisy Zamora, Jun Yang, Bruce D Hammock, Ameer Y Taha
Linoleic acid (LA) and α-linolenic acid (ALA) in plant or algae oils are precursors to oxidized fatty acid metabolites known as oxylipins. Liquid chromatography tandem mass spectrometry was used to quantify oxylipins in soybean, corn, olive, canola, and four high-oleic acid algae oils at room temperature or after heating for 10 min at 100 °C. Flaxseed oil oxylipin concentrations were determined in a follow-up experiment that compared it to soybean, canola, corn, and olive oil. Published consumption data for soybean, canola, corn, and olive oil were used to estimate daily oxylipin intake...
February 28, 2017: Journal of Agricultural and Food Chemistry
https://www.readbyqxmd.com/read/28140765/effect-of-oil-droplet-size-on-the-oxidative-stability-of-spray-dried-flaxseed-oil-powders
#17
Hirokazu Shiga, Tze Loon Neoh, Ai Ninomiya, Sae Adachi, Ignacio Lopez Pasten, Shuji Adachi, Hidefumi Yoshii
The effect of the size of oil droplets on the oxidative stability of flaxseed oil in spray-dried powders was investigated. Maltodextrin with a dextrose equivalent of 25 was used as a wall material, and sodium caseinate and transglutaminase-polymerized sodium caseinate were used as emulsifiers. The oxidative stability of flaxseed oil encapsulated in the spray-dried powders was evaluated using lipid oxidation and conductometric determination tests at 105 °C. The powders containing larger oil droplets exhibited higher surface oil content after spray drying, and higher peroxide value and conductivity after storage at 105 °C...
April 2017: Bioscience, Biotechnology, and Biochemistry
https://www.readbyqxmd.com/read/28135396/chemical-composition-analysis-sensory-and-feasibility-study-of-tree-peony-seed
#18
Yingyi Mao, Jigang Han, Fang Tian, Xue Tang, Yonghong Hu, Yan Guan
Eight wild species in Sect. Moutan DC (tree peony) of the genus Paeonia grown in natural habitats and 1 cultivated specie were investigated to analyze their fatty acid and bioactive phenolic compound profiles. For fatty acid composition, P. ludlowii contained the lowest α-linolenic acid (27.68%) and P. jishanensis contained the highest (51.96 %) content of the 9 species. For phenolic compounds, P. qiui contained the highest resveratrol (2.12 mg/g), P. delavayi contained the highest β-gentiobiosylpaeoniflorin (26...
January 30, 2017: Journal of Food Science
https://www.readbyqxmd.com/read/28133904/lifelong-intake-of-flaxseed-or-menhaden-oil-to-provide-varying-n-6-to-n-3-pufa-ratios-modulate-bone-microarchitecture-during-growth-but-not-after-ovx-in-sprague-dawley-rats
#19
Amanda B Longo, Phillip J Sullivan, Sandra J Peters, Paul J LeBlanc, Gregory R Wohl, Wendy E Ward
SCOPE: Skeletal health is a lifelong process impacted by environmental factors, including nutrient intake. The n-3 source and PUFA ratio affect bone health in growing rats, or following ovariectomy (OVX), but no study has investigated the longitudinal effect of PUFA-supplementation throughout these periods of bone development. METHODS AND RESULTS: One month old, Sprague-Dawley rats (n = 98) were randomized to receive 1 of 4 diets from 1 through 6 months of age. Diets were modified from AIN-93G to contain a varying amount and source of n-3 (flaxseed versus menhaden oil) to provide an n-6 to n-3 ratio of 10:1 or 5:1...
January 29, 2017: Molecular Nutrition & Food Research
https://www.readbyqxmd.com/read/28108729/comparative-omega-3-fatty-acid-enrichment-of-egg-yolks-from-first-cycle-laying-hens-fed-flaxseed-oil-or-ground-flaxseed
#20
I J Ehr, M E Persia, E A Bobeck
When laying hen diets are enriched with omega-3 polyunsaturated fatty acids to generate value-added eggs for human consumption markets, concentrations of alpha-linolenic (ALA), eicosapentaenoic (EPA), and docosahexaenoic acids (DHA) in the yolk can reach 250 mg/50 g whole egg. Flaxseed, a rich source of ALA, is commonly used for omega-3 enrichment; however, the impact of dietary flaxseed source (extracted oil vs. milled seed) on fatty acid transfer to egg yolk in laying hens is unknown. Therefore, transfer of ALA, EPA, and DHA into egg yolk from extracted flaxseed oil or milled flaxseed was evaluated in Hy-Line W-36 laying hens over an 8-week feeding period (25 to 33 wk old)...
January 20, 2017: Poultry Science
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