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Flaxseed oil

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https://www.readbyqxmd.com/read/29350755/microbial-and-chemical-shelf-life-of-vacuum-steam-pasteurized-whole-flaxseed-and-milled-flaxseed
#1
Manoj Shah, Bridget Eklund, Luiz Gustavo Conde Lima, Teresa Bergholz, Clifford Hall
Flaxseed is an oilseed with many health benefits. Flaxseed may be consumed raw or in processed form. In the raw form, there is a potential for microbial contamination. Several pasteurization methods have been used to reduce microbial contamination. However, such treatments may affect chemical properties of foods. In this study, vacuum steam-pasteurization was conducted on whole flaxseed and milled flaxseed using 4 different conditions (3 min at 75 °C, 3 min at 90 °C, 9 min at 90 °C, and 3 min at 105 °C)...
January 19, 2018: Journal of Food Science
https://www.readbyqxmd.com/read/29342901/omega-3-polyunsaturated-fatty-acids-time-dependently-reduce-cell-viability-and-oncogenic-microrna-21-expression-in-estrogen-receptor-positive-breast-cancer-cells-mcf-7
#2
Lauren LeMay-Nedjelski, Julie K Mason-Ennis, Amel Taibi, Elena M Comelli, Lilian U Thompson
The omega-3 polyunsaturated fatty acid (n-3 PUFA), α-linolenic acid (ALA), and its metabolites, eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), independently reduce the growth of breast cancer cells in vitro, but the mechanisms, which may involve microRNA (miRNA), are still unclear. The expression of the oncomiR, miR-21, is reduced by DHA treatment, but the effects of ALA on miR-21, alone or combined with EPA and DHA under physiologically relevant concentrations, have not been investigated. The effects of ALA alone and +/-EPA and DHA at the blood molar ratios seen in either humans (1...
January 14, 2018: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/29323210/anticancer-potentiality-of-lignan-rich-fraction-of-six-flaxseed-cultivars
#3
Shahira M Ezzat, Samia A Shouman, Abeer Elkhoely, Yasmin M Attia, Mohamed S Elsesy, Amira S El Senousy, Mouchira A Choucry, Sabah H El Gayed, Abeer A El Sayed, Essam Abdel Sattar, Nebal El Tanbouly
The objective of our study is to highlight the therapeutic effect and mechanism of action by which purified Flaxseed hydrolysate (PFH) which is a lignan rich fraction exerts its anticancer activity on a human breast cancer cell line (T47D) and in mice bearing tumor. HPLC analysis of PFH of six flaxseed cultivars had shown that PFH of the cultivar Giza 9 (PFH-G9) contains the highest concentration of SDG (81.64 mg/g). The in vitro cytotoxic potentiality of PFH's of six flaxseed cultivars was screened against a panel of human cancer cell lines...
January 11, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29287462/enzymatic-esterification-of-acylglycerols-rich-in-omega-3-from-flaxseed-oil-by-an-immobilized-solvent-tolerant-lipase-from-actinomadura-sediminis-utmc-2870-isolated-from-oil-contaminated-soil
#4
Somaye Imanparast, Javad Hamedi, Mohammad Ali Faramarzi
Polyunsaturated fatty acids (PUFAs) are essential to human health and can be produced by enzymatic esterification. Actinomadura sediminis UTMC 2870 isolated from oil-contaminated soil contained a lipase that was stable at varying pH and in various solvents, salts, and chemicals. This lipase exhibited high efficiency for omega-3 (n-3), and its production was optimized using a response surface method. Acylglycerols (AGs) rich in n-3 were produced by extraction of the free fatty acids (FFAs) from flaxseed oil, concentration of PUFAs, and enzymatic esterification by the Celite-immobilized lipase...
April 15, 2018: Food Chemistry
https://www.readbyqxmd.com/read/29274984/production-milk-and-plasma-fatty-acid-profile-and-nutrient-utilization-in-jersey-cows-fed-flaxseed-oil-and-corn-grain-with-different-particle-size
#5
V Brossillon, S F Reis, D C Moura, J G B Galvão, A S Oliveira, C Côrtes, A F Brito
We aimed to compare the effects of ground (GC) or cracked corn (CC), with or without flaxseed oil (FSO), on milk yield, milk and plasma fatty acid (FA) profile, and nutrient digestibility in Jersey cows fed diets formulated to contain similar starch concentrations. Twelve multiparous organic-certified Jersey cows averaging (mean ± standard deviation) 455 ± 41.9 kg of body weight and 152 ± 34 d in milk and 4 primiparous organic-certified Jersey cows averaging (mean ± standard deviation) 356 ± 2.41 kg of body weight and 174 ± 30 d in milk in the beginning of the experiment were used...
December 20, 2017: Journal of Dairy Science
https://www.readbyqxmd.com/read/29229363/comparison-of-the-effects-of-flaxseed-oil-and-sunflower-seed-oil-consumption-on-serum-glucose-lipid-profile-blood-pressure-and-lipid-peroxidation-in-patients-with-metabolic-syndrome
#6
Atefeh Akrami, Farzad Nikaein, Siavash Babajafari, Shiva Faghih, Hassan Yarmohammadi
BACKGROUND: Metabolic syndrome (MetSyn) increases the risk of type II diabetes and morbidity and mortality due to cardiovascular diseases. Flaxseed oil (FO), as a functional food, is one of the major vegetal sources of essential omega-3 fatty acids. OBJECTIVE: This study aimed to compare the effects of consumption of FO and sunflower seed oil (SO) on lipid peroxidation and other symptoms of MetSyn. METHODS: This randomized controlled interventional trial was conducted on 60 volunteers aged 30 to 60 years who were diagnosed with MetSyn in Shiraz, Iran...
November 20, 2017: Journal of Clinical Lipidology
https://www.readbyqxmd.com/read/29228348/flaxseed-supplementation-on-glucose-control-and-insulin-sensitivity-a-systematic-review-and-meta-analysis-of-25-randomized-placebo-controlled-trials
#7
Mohsen Mohammadi-Sartang, Zahra Sohrabi, Reza Barati-Boldaji, Hamidreza Raeisi-Dehkordi, Zohreh Mazloom
Context: The results of human clinical trials investigating the effects of flaxseed on glucose control and insulin sensitivity are inconsistent. Objective: The present study aimed to systematically review and analyze randomized controlled trials assessing the effects of flaxseed consumption on glycemic control. Data Sources: PubMed, Medline via Ovid, SCOPUS, EMBASE, and ISI Web of Sciences databases were searched up to November 2016. Study Selection: Clinical trials in which flaxseed or its products were administered as an intervention were included...
December 8, 2017: Nutrition Reviews
https://www.readbyqxmd.com/read/29175142/flaxseed-oil-rich-in-omega-3-protects-aorta-against-inflammation-and-endoplasmic-reticulum-stress-partially-mediated-by-gpr120-receptor-in-obese-diabetic-and-dyslipidemic-mice-models
#8
Alexandre Moura-Assis, Milessa Silva Afonso, Vanessa de Oliveira, Joseane Morari, Gustavo Aparecido Dos Santos, Marcia Koike, Ana Maria Lottenberg, Rodrigo Ramos Catharino, Licio Augusto Velloso, Adelino Sanchez Ramos da Silva, L P de Moura, Eduardo Rochete Ropelle, José Rodrigo Pauli, Dennys Esper Corrêa Cintra
The "first hit" to atherogenesis is driven by toll-like receptor 4, endoplasmic reticulum stress and ultimately metabolic dysfunction. In this study, we hypothesized that a flaxseed oil-enriched diet (FS) abolishes these inflammatory signaling pathway and restore metabolic homeostasis by activating the fatty acid receptor GPR120 in aorta of obese mice. Glucose homeostasis was assessed by GTT and ITT; lipidomics was performed using a Hybrid Ion Trap-Orbitrap Mass Spectrometer; serum lipids were measured using colorimetric assays; GPR120 and infiltrating macrophages were analyzed by immunofluorescence; protein immunoprecipitation and gene expression were evaluated by Western blot and RT-PCR, respectively...
October 18, 2017: Journal of Nutritional Biochemistry
https://www.readbyqxmd.com/read/29174030/position-paper-on-vegetarian-diets-from-the-working-group-of-the-italian-society-of-human-nutrition
#9
C Agnoli, L Baroni, I Bertini, S Ciappellano, A Fabbri, M Papa, N Pellegrini, R Sbarbati, M L Scarino, V Siani, S Sieri
BACKGROUND: Interest in vegetarian diets is growing in Italy and elsewhere, as government agencies and health/nutrition organizations are emphasizing that regular consumption of plant foods may provide health benefits and help prevent certain diseases. METHODS AND RESULTS: We conducted a Pubmed search, up to September, 2015, for studies on key nutrients (proteins, vitamin B12, iron, zinc, calcium, vitamin D, and n-3 fatty acids) in vegetarian diets. From 295 eligible publications the following emerged: Vegetarians should be encouraged to supplement their diets with a reliable source of vitamin B12 (vitamin-fortified foods or supplements)...
October 31, 2017: Nutrition, Metabolism, and Cardiovascular Diseases: NMCD
https://www.readbyqxmd.com/read/29167527/the-effects-of-diets-enriched-in-omega-3-polyunsaturated-fatty-acids-on-systemic-vaccinia-virus-infection
#10
Gwendolyn J B Jones, Rachel L Roper
Omega-3 polyunsaturated fatty acids (PUFA, n-3 fatty acids), the key components of fish and flaxseed oils, are increasingly consumed by the public because of their potential health benefits and are available by prescription for hypertriglyceridemia. However, numerous studies have shown that these compounds are immunoregulatory and immunosuppressive and thus may increase susceptibility to infection. In this study, we tested the effects of the amount of fat and the types of fatty acid in the diet on infection by vaccinia virus, an acute infection that begins in the respiratory tract and spreads by viremia to internal organs...
November 22, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29143841/ionic-liquids-as-stationary-phases-for-fatty-acid-analysis-by-gas-chromatography
#11
REVIEW
C Fanali, G Micalizzi, P Dugo, L Mondello
The present paper provides an overview of the application of ionic liquid (IL) columns for GC analysis of fatty acid methyl esters (FAMEs). Although their separation can be carried out utilizing GC columns containing polar stationary phases, some ILs have been employed as stationary phases, either commercial or laboratory made, in GC analysis. Monodimensional and bidimensional GC methods have been optimized in order to achieve the best separation especially considering the geometric and positional isomers of unsaturated fatty acids...
November 16, 2017: Analyst
https://www.readbyqxmd.com/read/29117618/the-effects-of-flaxseed-oil-omega-3-fatty-acids-supplementation-on-metabolic-status-of-patients-with-polycystic-ovary-syndrome-a-randomized-double-blind-placebo-controlled-trial
#12
Golara Mirmasoumi, Mohammad Fazilati, Fatemeh Foroozanfard, Zahra Vahedpoor, Samaneh Mahmoodi, Mohsen Taghizadeh, Nazanin Kazemi Esfeh, Maryam Mohseni, Hassan Karbassizadeh, Zatollah Asemi
Objective This study was conducted to evaluate the effects of flaxseed oil omega-3 fatty acids supplementation on metabolic status of patients with polycystic ovary syndrome (PCOS). Methods This randomized double-blind, placebo-controlled trial was conducted on 60 women with PCOS according to the Rotterdam criteria aged 18-40 years old. Participants were randomly assigned into two groups to receive either 1,000 mg flaxseed oil omega-3 fatty acids (n=30) or placebo (n=30) twice a day for 12 weeks. Metabolic, endocrine, inflammatory factors were quantified at baseline and after the 12-week intervention...
November 8, 2017: Experimental and Clinical Endocrinology & Diabetes
https://www.readbyqxmd.com/read/29114553/compare-the-effect-of-flaxseed-evening-primrose-oil-and-vitamin-e-on-duration-of-periodic-breast-pain
#13
Farzaneh Jaafarnejad, Elham Adibmoghaddam, Seyyed Ahmad Emami, Azadeh Saki
BACKGROUND: Breast periodic pain is the most common disorder of the breast which leads to consultation with knowledgeable people like a midwife. The aim of this study was to compare the therapeutic effect of flaxseed, evening primrose oil, and Vitamin E on the duration of the period of breast pain. MATERIALS AND METHODS: This study is a quasi-randomized clinical trial conducted in 2015 on ninety patients complaining of breast periodic pain referring to Gynecologic Clinics of Ghaem Hospital or residents living in dormitories of Mashhad University of Medical Sciences...
2017: Journal of Education and Health Promotion
https://www.readbyqxmd.com/read/29089855/solid-state-fermentation-reduces-phytic-acid-level-improves-the-profile-of-myo-inositol-phosphates-and-enhances-the-availability-of-selected-minerals-in-flaxseed-oil-cake
#14
Robert Duliński, Bożena Stodolak, Łukasz Byczyński, Aleksander Poreda, Anna Starzyńska-Janiszewska, Krzysztof Żyła
Flaxseed oil cake was subjected to fermentation with Rhizopus oligosporus (DSM 1964 and ATCC 64063), and the phytate (InsP6) content, myo-inositol phosphate profile and in vitro bioavailability of essential minerals were studied. Flaxseed oil cake had a phytate mass fraction of 13.9 mg/g. A 96-hour fermentation of flaxseed oil cake by R. oligosporus DSM 1964 and R. oligosporus ATCC 64063 decreased the InsP6 content by 48 and 33%, respectively. The strains had different phytate-degrading activities: fermentation of flaxseed oil cake with R...
September 2017: Food Technology and Biotechnology
https://www.readbyqxmd.com/read/29083494/protective-role-of-flaxseed-oil-and-flaxseed-lignan-secoisolariciresinol-diglucoside-against-oxidative-stress-in-rats-with-metabolic-syndrome
#15
Bruna Pilar, Angélica Güllich, Patrícia Oliveira, Deise Ströher, Jacqueline Piccoli, Vanusa Manfredini
This study evaluated the protective effect of flaxseed oil (FO) and flaxseed lignan secoisolariciresinol diglucoside (SDG) against oxidative stress in rats with metabolic syndrome (MS). 48 rats were allocated into the following 6 groups: Groups 1 (control), 5 (FO), and 6 (SDG) received water and were treated daily orally with saline, FO, and SDG, respectively. Groups 2 (MS), 3 (MS+FO), and 4 (MS+SDG) received 30% fructose in drinking water for MS induction and were treated daily orally with saline, FO, and SDG, respectively...
October 30, 2017: Journal of Food Science
https://www.readbyqxmd.com/read/29081885/dietary-flaxseed-oil-prevents-western-type-diet-induced-nonalcoholic-fatty-liver-disease-in-apolipoprotein-e-knockout-mice
#16
Hao Han, Fubin Qiu, Haifeng Zhao, Haiying Tang, Xiuhua Li, Dongxing Shi
The prevalence of nonalcoholic fatty liver disease (NAFLD) has dramatically increased globally during recent decades. Intake of n-3 polyunsaturated fatty acids (PUFAs), mainly eicosapentaenoic acid (EPA, C20:5n-3) and docosahexaenoic acid (DHA, C22:6n-3), is believed to be beneficial to the development of NAFLD. However, little information is available with regard to the effect of flaxseed oil rich in α-linolenic acid (ALA, C18:3n-3), a plant-derived n-3 PUFA, in improving NAFLD. This study was to gain the effect of flaxseed oil on NAFLD and further investigate the underlying mechanisms...
2017: Oxidative Medicine and Cellular Longevity
https://www.readbyqxmd.com/read/29064409/effect-of-altering-dietary-n-6-n-3-polyunsaturated-fatty-acid-ratio-with-plant-and-marine-based-supplement-on-biomarkers-of-bone-turnover-in-healthy-adults
#17
Sujatha Rajaram, Ellen Lan Yip, Rajneesh Reghunathan, Subburaman Mohan, Joan Sabaté
Although there is accumulating evidence for a protective role of n-3 polyunsaturated fatty acids (n-3 PUFAs) on bone health, there are limited studies that examine the effect of altering dietary n-6:n-3 PUFA ratio with plant and marine sources of n-3 PUFA on bone health. Healthy adults (n = 24) were randomized into an eight-week crossover study with a four-week washout between treatments, with each subject consuming three of four diets. The four diets differed in the dietary n-6:n-3 PUFA ratios and either had an algal oil supplement added or not: (Control diet (10:1); α-linolenic acid (ALA) diet (2:1); Eicosapentaenoic acid/Docosahexaenoic acid (EPA/DHA) diet (10:1 plus supplement (S) containing EPA/DHA; Combination diet (2:1 + S))...
October 24, 2017: Nutrients
https://www.readbyqxmd.com/read/29051664/status-of-the-bioactive-phytoceuticals-during-deep-fat-frying-of-snack-food-using-nutra-coconut-oil
#18
M Maneesh Kumar, Sheema Faiza, Sukumar Debnath, Nasirullah
The present study was carried out to study the physico-chemical changes that take place in both product and oil during the deep fat frying of a traditional savoury snack 'kodubale', at 120-160 °C for 120-600 s using coconut oil (CO) and nutra-coconut oil (NCO). Further, kinetic studies on moisture loss, oil uptake, color and degradation of β-carotene, total polyphenol content and antioxidant activity for kodubale was carried out during frying as a function of temperature and time. The study showed that the kinetic coefficients for above parameters increased with temperature and time and the data obtained were well fitted with first order kinetic model...
October 2017: Journal of Food Science and Technology
https://www.readbyqxmd.com/read/29023751/the-use-of-factorial-design-to-evaluate-the-oxidation-of-oils-containing-different-types-of-omega-3-fatty-acids
#19
Thamyris Dias Fabiano Agnes, Gabriela Grassmann Roschel, Inar Alves Castro
N3 FA promote beneficial effects on cardiovascular diseases, but they are highly susceptible to oxidation, which leads to the formation of potentially toxic secondary products. In this study, the antioxidant capacity of natural compounds (sinapic acid and rutin) was evaluated using an accelerated model to oxidize the oils. Five inducers (Temperature, Fe(2+) , AAPH, Ascorbyl palmitate and AMVN) were combined in a factorial design to accelerate the oxidation of three oils (flaxseed, echium and fish) containing different sources of n3 FA...
October 11, 2017: Journal of the Science of Food and Agriculture
https://www.readbyqxmd.com/read/28992014/the-digestible-energy-metabolizable-energy-and-net-energy-content-of-dietary-fat-sources-in-thirteen-and-fifty-kilogram-pigs
#20
T A Kellner, J F Patience
The objective was to determine the energy concentration of a diverse array of dietary fat sources and, from these data, develop regression equations that explain differences based on chemical composition. A total of 120 Genetiporc 6.0 × Genetiporc F25 (PIC, Inc., Hendersonville, TN) individually housed barrows were studied for 56 d. These barrows (initial BW of 9.9 ± 0.6 kg) were randomly allotted to 1 of 15 dietary treatments. Each experimental diet included 95% of a corn-soybean meal basal diet plus 5% either corn starch or 1 of 14 dietary fat sources...
September 2017: Journal of Animal Science
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