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Flaxseed oil

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https://www.readbyqxmd.com/read/28335388/a-combination-of-flaxseed-oil-and-astaxanthin-improves-hepatic-lipid-accumulation-and-reduces-oxidative-stress-in-high-fat-diet-fed-rats
#1
Jiqu Xu, Shuang Rong, Hui Gao, Chang Chen, Wei Yang, Qianchun Deng, Qingde Huang, Lingyun Xiao, Fenghong Huang
Hepatic lipid accumulation and oxidative stress are crucial pathophysiological mechanisms for non-alcoholic fatty liver disease (NAFLD). Thus, we examined the effect of a combination of flaxseed oil (FO) and astaxanthin (ASX) on hepatic lipid accumulation and oxidative stress in rats fed a high-fat diet. ASX was dissolved in flaxseed oil (1 g/kg; FO + ASX). Animals were fed diets containing 20% fat, where the source was lard, or 75% lard and 25% FO + ASX, or 50% lard and 50% FO + ASX, or FO + ASX, for 10 weeks...
March 13, 2017: Nutrients
https://www.readbyqxmd.com/read/28320208/fresh-cheese-as-a-vehicle-for-polyunsaturated-fatty-acids-integration-effect-on-physico-chemical-microbiological-and-sensory-characteristics
#2
Barbara Dal Bello, Luisa Torri, Maria Piochi, Marta Bertolino, Giuseppe Zeppa
Five different vegetable oils were used in the production of fresh cheese to increase the concentration of polyunsaturated fatty acids (PUFAs), particularly α-linolenic acid (ALA), the most important omega-3 fatty acid of vegetable origin. Physico-chemical and microbiological characteristics of functionalized cheeses were evaluated after 1 and 3 days of ripening at 4 °C while the consumer appreciation was evaluated in the final product at 3 days of ripening. After 3 days, the cheeses with Camelina sativa and Echium plantagineum oils added exhibited the highest retention of PUFAs (mostly ALA) compared to those with flaxseed, raspberry and blackcurrant oils...
March 20, 2017: International Journal of Food Sciences and Nutrition
https://www.readbyqxmd.com/read/28284063/soybean-polar-lipids-differently-impact-adipose-tissue-inflammation-and-the-endotoxin-transporters-lbp-and-scd14-in-flaxseed-vs-palm-oil-rich-diets
#3
Manon Lecomte, Leslie Couëdelo, Emmanuelle Meugnier, Emmanuelle Loizon, Pascale Plaisancié, Annie Durand, Alain Géloën, Florent Joffre, Carole Vaysse, Marie-Caroline Michalski, Fabienne Laugerette
Obesity and type 2 diabetes are nutritional pathologies, characterized by a subclinical inflammatory state. Endotoxins are now well recognized as an important factor implicated in the onset and maintain of this inflammatory state during fat digestion in high-fat diet. As a preventive strategy, lipid formulation could be optimized to limit these phenomena, notably regarding fatty acid profile and PL emulsifier content. Little is known about soybean polar lipid (SPL) consumption associated to oils rich in saturated FA vs...
February 21, 2017: Journal of Nutritional Biochemistry
https://www.readbyqxmd.com/read/28277795/a-reduced-cost-strategy-for-enriching-chicken-meat-with-omega-3-long-chain-polyunsaturated-fatty-acids-using-dietary-flaxseed-oil
#4
K Kanakri, J Carragher, R Hughes, B Muhlhausler, R Gibson
1. This study aimed to determine the minimal duration required for feeding male broilers (Cobb 500) with a flaxseed oil diet while still retaining long chain omega-3 polyunsaturated fatty acid (n-3 LCPUFA) accumulation in the meat at a desirable level. 2. Three groups of broilers (60 each) were fed on a 3% flaxseed oil (high α-linolenic acid (ALA)) diet for either 6, 4 or 2 weeks prior to slaughter. During the remaining time they were maintained on a 3% macadamia oil (low ALA) diet. A fourth group (Control, n=60) was fed on a commercial diet for 6 weeks...
February 15, 2017: British Poultry Science
https://www.readbyqxmd.com/read/28250313/nutritional-evaluation-of-oleogel-made-from-micronutrient-rich-edible-oils
#5
Moumita Ghosh, Faruk Begg, Dipak K Bhattacharyya, Nilratan Bandyopadhya, Mahua Ghosh
The present study examined the nutritional properties of trans-free edible oleogels made from oil blends of rice bran and flaxseed in animal model. Oleogels were prepared by using mixture of palm stearin (PS) with cetyl laurate (CL) and palm stearin (PS) with cetyl caprylate (CC) as oleogelators. The oleogel samples were prepared with 15 weight % oleogelators (2:1 molar ratio of PS:CC or PS:CL) at 60°C with 1 hr constant stirring in blended oil. The prepared oleogel samples were subjected to DSC and XRD studies in order to evaluate their melting and crystal characteristics...
2017: Journal of Oleo Science
https://www.readbyqxmd.com/read/28242936/effect-of-flaxseed-oil-and-flour-on-sensory-physicochemical-and-fatty-acid-profile-of-the-fruit-yoghurt
#6
S Siva Kumar, B V Balasubramanyam, K Jayaraj Rao, P Heartwin Amala Dhas, B Surendra Nath
The objective of this study was to incorporate flaxseed oil, flaxseed flour and fruits for the preparation of fruit yoghurt and analysed for their sensory, physicochemical and fatty acid profile. Overall acceptability of sensory scores indicates that fruit yoghurt (20% fruit and sugar mixture) with incorporation of flaxseed oil up to 2% and flaxseed flour up to 1% in combination can be used for preparation of fruit yoghurt with acceptable sensory attributes. The scores drastically reduced for yoghurt samples wherein 2% flaxseed flour was incorporated...
February 2017: Journal of Food Science and Technology
https://www.readbyqxmd.com/read/28228158/flaxseed-oil-ameliorates-alcoholic-liver-disease-via-anti-inflammation-and-modulating-gut-microbiota-in-mice
#7
Xiaoxia Zhang, Hao Wang, Peipei Yin, Hang Fan, Liwei Sun, Yujun Liu
BACKGROUND: Alcoholic liver disease (ALD) represents a chronic wide-spectrum of liver injury caused by consistently excessive alcohol intake. Few satisfactory advances have been made in management of ALD. Thus, novel and more practical treatment options are urgently needed. Flaxseed oil (FO) is rich in α-linolenic acid (ALA), a plant-derived n-3 polyunsaturated fatty acids (PUFAs). However, the impact of dietary FO on chronic alcohol consumption remains unknown. METHODS: In this study, we assessed possible effects of dietary FO on attenuation of ALD and associated mechanisms in mice...
February 22, 2017: Lipids in Health and Disease
https://www.readbyqxmd.com/read/28209094/attenuation-of-arsenic-trioxide-induced-cardiotoxicity-through-flaxseed-oil-in-experimental-rats
#8
Mathews V Varghese, M Abhilash, Manju Alex, M V Sauganth Paul, A Prathapan, K G Raghu, R Harikumaran Nair
OBJECTIVES: Arsenic trioxide (As2O3) is a potent drug for acute promyelocytic leukaemia, but its clinical trials are allied with some serious adverse events mainly cardiac functional abnormalities. So the objective of our investigation is to identify the cardioprotective action of flaxseed oil (FSO), a natural compound against As2O3 induced cardiotoxicity. METHODS: Male wistar rats were treated with As2O3 (4 mg/kg) to induce cardiotoxicity. FSO (250 and 500 mg/kg) was given in combination with As2O3 for evaluating its cardioprotective efficacy...
February 17, 2017: Redox Report: Communications in Free Radical Research
https://www.readbyqxmd.com/read/28157307/lipidomic-analysis-of-oxidized-fatty-acids-in-plant-and-algae-oils
#9
Christine E Richardson, Marie Hennebelle, Yurika Otoki, Daisy Zamora, Jun Yang, Bruce D Hammock, Ameer Y Taha
Linoleic acid (LA) and α-linolenic acid (ALA) in plant or algae oils are precursors to oxidized fatty acid metabolites known as oxylipins. Liquid chromatography tandem mass spectrometry was used to quantify oxylipins in soybean, corn, olive, canola, and four high-oleic acid algae oils at room temperature or after heating for 10 min at 100 °C. Flaxseed oil oxylipin concentrations were determined in a follow-up experiment that compared it to soybean, canola, corn, and olive oil. Published consumption data for soybean, canola, corn, and olive oil were used to estimate daily oxylipin intake...
February 28, 2017: Journal of Agricultural and Food Chemistry
https://www.readbyqxmd.com/read/28140765/effect-of-oil-droplet-size-on-the-oxidative-stability-of-spray-dried-flaxseed-oil-powders
#10
Hirokazu Shiga, Tze Loon Neoh, Ai Ninomiya, Sae Adachi, Ignacio Lopez Pasten, Shuji Adachi, Hidefumi Yoshii
The effect of the size of oil droplets on the oxidative stability of flaxseed oil in spray-dried powders was investigated. Maltodextrin with a dextrose equivalent of 25 was used as a wall material, and sodium caseinate and transglutaminase-polymerized sodium caseinate were used as emulsifiers. The oxidative stability of flaxseed oil encapsulated in the spray-dried powders was evaluated using lipid oxidation and conductometric determination tests at 105 °C. The powders containing larger oil droplets exhibited higher surface oil content after spray drying, and higher peroxide value and conductivity after storage at 105 °C...
April 2017: Bioscience, Biotechnology, and Biochemistry
https://www.readbyqxmd.com/read/28135396/chemical-composition-analysis-sensory-and-feasibility-study-of-tree-peony-seed
#11
Yingyi Mao, Jigang Han, Fang Tian, Xue Tang, Yonghong Hu, Yan Guan
Eight wild species in Sect. Moutan DC (tree peony) of the genus Paeonia grown in natural habitats and 1 cultivated specie were investigated to analyze their fatty acid and bioactive phenolic compound profiles. For fatty acid composition, P. ludlowii contained the lowest α-linolenic acid (27.68%) and P. jishanensis contained the highest (51.96 %) content of the 9 species. For phenolic compounds, P. qiui contained the highest resveratrol (2.12 mg/g), P. delavayi contained the highest β-gentiobiosylpaeoniflorin (26...
January 30, 2017: Journal of Food Science
https://www.readbyqxmd.com/read/28133904/lifelong-intake-of-flaxseed-or-menhaden-oil-to-provide-varying-n-6-to-n-3-pufa-ratios-modulate-bone-microarchitecture-during-growth-but-not-after-ovx-in-sprague-dawley-rats
#12
Amanda B Longo, Phillip J Sullivan, Sandra J Peters, Paul J LeBlanc, Gregory R Wohl, Wendy E Ward
SCOPE: Skeletal health is a lifelong process impacted by environmental factors, including nutrient intake. The n-3 source and PUFA ratio affect bone health in growing rats, or following ovariectomy (OVX), but no study has investigated the longitudinal effect of PUFA-supplementation throughout these periods of bone development. METHODS AND RESULTS: One month old, Sprague-Dawley rats (n = 98) were randomized to receive 1 of 4 diets from 1 through 6 months of age. Diets were modified from AIN-93G to contain a varying amount and source of n-3 (flaxseed versus menhaden oil) to provide an n-6 to n-3 ratio of 10:1 or 5:1...
January 29, 2017: Molecular Nutrition & Food Research
https://www.readbyqxmd.com/read/28108729/comparative-omega-3-fatty-acid-enrichment-of-egg-yolks-from-first-cycle-laying-hens-fed-flaxseed-oil-or-ground-flaxseed
#13
I J Ehr, M E Persia, E A Bobeck
When laying hen diets are enriched with omega-3 polyunsaturated fatty acids to generate value-added eggs for human consumption markets, concentrations of alpha-linolenic (ALA), eicosapentaenoic (EPA), and docosahexaenoic acids (DHA) in the yolk can reach 250 mg/50 g whole egg. Flaxseed, a rich source of ALA, is commonly used for omega-3 enrichment; however, the impact of dietary flaxseed source (extracted oil vs. milled seed) on fatty acid transfer to egg yolk in laying hens is unknown. Therefore, transfer of ALA, EPA, and DHA into egg yolk from extracted flaxseed oil or milled flaxseed was evaluated in Hy-Line W-36 laying hens over an 8-week feeding period (25 to 33 wk old)...
January 20, 2017: Poultry Science
https://www.readbyqxmd.com/read/28101573/combining-doxorubicin-with-a-phenolic-extract-from-flaxseed-oil-evaluation-of-the-effect-on-two-breast-cancer-cell-lines
#14
Eliana Guerriero, Angela Sorice, Francesca Capone, Gabriella Storti, Giovanni Colonna, Gennaro Ciliberto, Susan Costantini
Breast cancer is one of the most frequently diagnosed forms of cancer and different treatments are used to block its progression. However, it still represents a very common cause of death in women. Doxorubicin (Dox) is reported as an effective agent in breast cancer treatment nonetheless it induces many side‑effects. For this reason, many laboratories are engaged in understanding how it is possible to decrease the drug concentration, considering that one of the possible solutions is to use drug synergy, combining it with natural substances...
February 2017: International Journal of Oncology
https://www.readbyqxmd.com/read/27990659/oxidative-stability-of-sesame-and-flaxseed-oils-and-their-effects-on-morphometric-and-biochemical-parameters-in-an-animal-model
#15
Priscila S Figueiredo, Camila J Candido, Jeandre As Jaques, Ângela A Nunes, Anderson Rl Caires, Flávio Santana Michels, Jeeser A Almeida, Wander Fo Filiú, Priscila A Hiane, Valter A Nascimento, Octavio L Franco, Rita Ca Guimarães
BACKGROUND: Sesame and flaxseed oils, which are rich in essential n-6 and n-3 polyunsaturated fatty acids, are widely consumed. We have determined the optical behavior with the quality and identity of cold-pressed sesame and flaxseed oils. The effects of these oils and their combinations on metabolic parameters in animal models were also measured. RESULTS: Flaxseed oil emitted carotenoid fluorescence (500-650 nm), but it was more unstable than sesame oil, which had a larger induction period by the Rancimat method...
December 18, 2016: Journal of the Science of Food and Agriculture
https://www.readbyqxmd.com/read/27941179/flaxseed-oil-supplementation-manipulates-correlations-between-serum-individual-mol-free-fatty-acid-levels-and-insulin-resistance-in-type-2-diabetics-insulin-resistance-and-percent-remaining-pancreatic-%C3%AE-cell-function-are-unaffected
#16
RANDOMIZED CONTROLLED TRIAL
D E Barre, K A Mizier-Barre, O Griscti, K Hafez
OBJECTIVES: Elevated total serum free fatty acids (FFAs) concentrations have been suggested, controversially, to enhance insulin resistance and decrease percent remaining β-cell function. However, concentrations of individual serum FFAs have never been published in terms of their relationship (correlation) to homeostatic model assessment-insulin resistance (HOMA-IR) and percent remaining β-cell function (HOMA-%β) in the type 2 diabetics (T2Ds). Alpha-linolenic acid consumption has a negative correlation with the insulin resistance, which in turn is negatively correlated with the remaining β-cell function...
October 1, 2016: Endocrine Regulations
https://www.readbyqxmd.com/read/27914517/effect-of-flaxseed-oil-and-microalgae-dha-on-the-production-performance-fatty-acids-and-total-lipids-of-egg-yolk-and-plasma-in-laying-hens
#17
M Neijat, O Ojekudo, J D House
The incorporation of omega-3 polyunsaturated fatty acids (PUFA) in the egg is dependent on both the transfer efficiency of preformed dietary omega-3 fatty acids to the eggs as well as endogenous PUFA metabolism and deposition. Employing an experimental design consisting of 70 Lohmann LSL-Classic hens (n=10/treatment) in a 6-week feeding trial, we examined the impact of graded levels of either flaxseed oil (alpha-linolenic acid, ALA) or algal DHA (preformed docosahexaenoic acid, DHA), each supplying 0.20%, 0...
December 2016: Prostaglandins, Leukotrienes, and Essential Fatty Acids
https://www.readbyqxmd.com/read/27904000/effects-of-flaxseed-oil-on-serum-lipids-and-lipoproteins-in-hemodialysis-patients-a-randomized-controlled-trial
#18
Maryam Mirfatahi, Hadi Tabibi, Alireza Nasrollahi, Mehdi Hedayati
INTRODUCTION: One of the major risk factors for cardiovascular disease is lipid abnormalities among hemodialysis patients. The present study was designed to investigate the effects of flaxseed oil consumption on serum lipids and lipoproteins in hemodialysis patients. MATERIALS AND METHODS: In a randomized double-blinded controlled trial, 34 hemodialysis patients were assigned to either the flaxseed oil or the control group. The patients in the flaxseed oil group received 6 g/d of flaxseed oil for 8 weeks, whereas the control group received 6 g/d of medium chain triglycerides oil...
November 2016: Iranian Journal of Kidney Diseases
https://www.readbyqxmd.com/read/27885786/effects-of-flaxseed-oil-on-blood-hepcidin-and-hematologic-factors-in-hemodialysis-patients
#19
Hadi Tabibi, Maryam Mirfatahi, Mehdi Hedayati, Alireza Nasrollahi
Introduction In hemodialysis (HD) patients, one of the common complications is renal anemia. Therefore, the present study was designed to investigate the effects of flaxseed oil consumption on blood hepcidin and hematologic factors in HD patients. Methods In this randomized, double-blind, clinical trial, 38 HD patients were randomly assigned to either the flaxseed oil or the control group. The patients in the flaxseed oil group received 6 g/d flaxseed oil for 8 wk, whereas the control group received 6 g/d medium chain triglycerides (MCT) oil...
November 25, 2016: Hemodialysis International
https://www.readbyqxmd.com/read/27881297/a-randomized-controlled-clinical-trial-investigating-the-effects-of-omega-3-fatty-acids-and-vitamin-e-co-supplementation-on-biomarkers-of-oxidative-stress-inflammation-and-pregnancy-outcomes-in-gestational-diabetes
#20
Mehri Jamilian, Shahrzad Hashemi Dizaji, Fereshteh Bahmani, Mohsen Taghizadeh, Mohammad Reza Memarzadeh, Maryam Karamali, Maryam Akbari, Zatollah Asemi
OBJECTIVES: Limited data are available for assessing the effects of omega-3 fatty acids and vitamin E co-supplementation on metabolic profiles and pregnancy outcomes in gestational diabetes (GDM). This study was designed to determine the effects of omega-3 fatty acids and vitamin E co-supplementation on biomarkers of oxidative stress, inflammation and pregnancy outcomes in women with GDM. METHODS: This randomized, double-blind, placebo-controlled clinical trial was conducted in 60 patients with GDM who were not taking oral hypoglycemic agents...
November 21, 2016: Canadian Journal of Diabetes
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