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Jeanne Leerssen, Rick Wassing, Jennifer R Ramautar, Diederick Stoffers, Oti Lakbila-Kamal, Joy Perrier, Jessica Bruijel, Jessica C Foster-Dingley, Moji Aghajani, Eus J W van Someren
Insomnia Disorder (ID) is the second-most common mental disorder and has a far-reaching impact on daytime functioning. A meta-analysis indicates that, of all cognitive domains, declarative memory involving the hippocampus is most affected in insomnia. Hippocampal functioning has consistently been shown to be sensitive to experimental sleep deprivation. Insomnia however differs from sleep deprivation in many aspects, and findings on hippocampal structure and function have been equivocal. The present study used both structural and resting-state functional Magnetic Resonance Imaging in a larger sample than previously reported to evaluate hippocampal volume and functional connectivity in ID...
February 12, 2018: Neurobiology of Learning and Memory
Do-Yang Park, Ji Ho Choi, So Young Kang, Jinjoo Han, Hun Yi Park, Jin Soon Hwang, Jae Ho Cho, Min Hyuk Cho, Hyun Jun Kim
OBJECTIVES: Pediatric obstructive sleep apnea has a relatively high prevalence and has various negative health and behavioral consequences. Among the various complications of pediatric obstructive sleep apnea, growth disturbance is still controversial. METHOD: 745 pediatric subjects with obstructive sleep apnea diagnosed by in-lab polysomnography were enrolled, after excluding ineligible subjects with abnormal growth related factors. Height, weight, and BMI of enrolled patients were measured and statistically converted to z-scores, and the converted data were analyzed statistically with the polysomnographic results...
March 2018: International Journal of Pediatric Otorhinolaryngology
Md Bashir Uddin, Chin-Moi Chow, Steven W Su
Sleep apnea (SA), a common sleep disorder, can significantly decrease the quality of life, and is closely associated with major health risk such as cardiovascular disease, sudden death, depression, and hypertension. Normal diagnostic process of SA using polysomnography (PSG) is costly and time consuming. In addition, the accuracy of different classification methods to detect SA varies with the use of different physiological signals. If an effective, reliable, and accurate classification method is developed, then the diagnosis of SA and their associated treatment will be time-efficient and economical...
February 15, 2018: Physiological Measurement
Afaf Akladious, Sausan Azzam, Yufen Hu, Pingfu Feng
OBJECTIVE: To determine the effect of Bmal1 knockdown (KD) on sleep, activity, immobility, hypothalamic levels of orexin, corticotrophin-releasing hormone (CRH), and GABAergic glutamate decarboxylase (GAD). METHODS: We used Bmal1 siRNA, or control siRNA intracerebroventricular (ICV) injection to knock down Bmal1 in C57BL/6 mice. Sleep polysomnography, wheel-running activity, and tail suspension test were performed. Polysomnographic (PSG) recordings in both groups were preceded by ICV injection made during both the light phase and the dark phase...
February 14, 2018: CNS Neuroscience & Therapeutics
Bernd Feige, Svetoslava Nanovska, Chiara Baglioni, Benedict Bier, Laura Cabrera, Sarah Diemers, Maximilian Quellmalz, Markus Siegel, Ireni Xeni, Andras Szentkiralyi, John-Peter Doerr, Dieter Riemann
Study Objectives: Insomnia disorder (ID) is a frequent sleep disorder coupled with increased risks for somatic and mental illness. While subjective complaints are severe, polysomnography (PSG) parameters show only modest differences between groups. REM sleep as the most aroused sleep state may be especially vulnerable to be perceived as wake. To directly assess possible differences, we determined auditory waking thresholds and sleep perception in ID patients and healthy control subjects (GSC) in N2 and REM sleep...
February 8, 2018: Sleep
Fernando Vaquerizo-Villar, Daniel Álvarez, Leila Kheirandish-Gozal, Gonzalo César Gutiérrez-Tobal, Verónica Barroso-García, Andrea Crespo, Félix Del Campo, David Gozal, Roberto Hornero
BACKGROUND AND OBJECTIVE: The aim of this study was to assess the utility of bispectrum-based oximetry approaches as a complementary tool to traditional techniques in the screening of pediatric sleep apnea-hypopnea syndrome (SAHS). METHODS: 298 blood oxygen saturation (SpO 2 ) signals from children ranging 0-13 years of age were recorded during overnight polysomnography (PSG). These recordings were divided into three severity groups according to the PSG-derived apnea hypopnea index (AHI): AHI < 5 events per hour (e/h), 5 ≤ AHI < 10 e/h, AHI ≥ 10 e/h...
March 2018: Computer Methods and Programs in Biomedicine
José Haba-Rubio, Helena Marti-Soler, Nadia Tobback, Daniela Andries, Pedro Marques-Vidal, Peter Vollenweider, Martin Preisig, Raphael Heinzer
OBJECTIVE: Periodic limb movements during sleep (PLMS) are prevalent in the general population, but their impact on sleep and association with cardiometabolic disorders are a matter of debate. METHODS: Data from 2162 participants (51.2% women, mean age 58.4 ± 11.1 years) of the population-based HypnoLaus study (Lausanne, Switzerland) were collected. Subjective sleep complaints and habits were assessed using the Pittsburgh Sleep Quality Index and the Epworth Sleepiness Scale (ESS)...
January 2018: Sleep Medicine
Dale C Capener, Matthew S Brock, Shana L Hansen, Panagiotis Matsangas, Vincent Mysliwiec
Introduction: Sleep disorders are increasingly recognized in active duty service members (ADSM). While there are multiple studies in male ADSM, there are limited data regarding sleep disorders in women in the military. The purpose of this study was to characterize sleep disorders in female ADSM referred for clinical evaluation to provide a better understanding of this unique population. Materials and Methods: We conducted a retrospective review of female ADSM who underwent a sleep medicine evaluation and an attended polysomnogram (PSG)...
February 7, 2018: Military Medicine
Selene Verde-Tinoco, Rafael Santana-Miranda, Romel Gutiérrez-Escobar, Reyes Haro, Joana Miranda-Ortiz, Talia Berruga-Fernandez, Ulises Jimenez-Correa, Adrián Poblano
Introduction: Reduced sleep to increase work hours is common among police officers, when this situation is combined with Obstructive sleep apnea/hypopnea syndrome (OSAHS), health consequences are greater, therefore we believe there is a need of research for these alterations. The aim of this study was to measure the changes in sleep architecture (SA) in police officers who currently have Night shift work (NSW) and OSAHS. Methods: We compared SA in 107 subjects divided in three groups: the first group included police officers with NSW and severe OSAHS (n = 48); the second group were non-police officers with diurnal work time and severe OSAHS (n = 48) and the third group was formed by healthy controls (n = 11)...
October 2017: Sleep Science
Bassam Chakar, Frédéric Senny, Anne-Lise Poirrier, Laurent Cambron, Julien Fanielle, Robert Poirrier
OBJECTIVE: In a device based on midsagittal jaw movements analysis, we assessed a sleep-wake automatic detector as an objective method to measure sleep in healthy adults by comparison with wrist actigraphy against polysomnography (PSG). METHODS: Simultaneous and synchronized in-lab PSG, wrist actigraphy and jaw movements were carried out in 38 healthy participants. Epoch by epoch analysis was realized to assess the ability to sleep-wake distinction. Sleep parameters as measured by the three devices were compared...
July 2017: Sleep Science
Stefanie De Jesus, Harry Prapavessis
INTRODUCTION: A number of mechanisms have been proposed to explain how exercise attenuates cravings among temporarily abstinent smokers; however, research has presented mixed findings. The aim of this study was to further investigate the mechanistic role of positive and negative affect and cortisol in the exercise-craving reduction relationship. METHODS: Adult smokers (N=110, male=56, M age=33.1, M cigarettes/day=15.4) provided baseline affective and cortisol data (T1)...
January 11, 2018: Addictive Behaviors
Handan İnönü Köseoğlu, Ahmet İnanır, Asiye Kanbay, Sevil Okan, Osman Demir, Osman Çeçen, Sema İnanır
OBJECTIVES: Fibromyalgia syndrome (FMS) is characterized by complaints of chronic musculoskeletal pain, fatigue, and difficulty in falling asleep. Obstructive sleep apnea syndrome (OSAS) is associated with symptoms, such as morning fatigueness and unrefreshing sleep. We aimed to investigate the presence of OSAS and objectively demonstrate changes in sleep pattern in patients with FMS. MATERIAL AND METHODS: Polysomnographic investigations were performed on 24 patients with FMS...
April 2017: Turkish thoracic journal
Mirja Quante, Emily R Kaplan, Michael Cailler, Michael Rueschman, Rui Wang, Jia Weng, Elsie M Taveras, Susan Redline
Objectives: Actigraphy is widely used to estimate sleep-wake time, despite limited information regarding the comparability of different devices and algorithms. We compared estimates of sleep-wake times determined by two wrist actigraphs (GT3X+ versus Actiwatch Spectrum [AWS]) to in-home polysomnography (PSG), using two algorithms (Sadeh and Cole-Kripke) for the GT3X+ recordings. Subjects and methods: Participants included a sample of 35 healthy volunteers (13 school children and 22 adults, 46% male) from Boston, MA, USA...
2018: Nature and Science of Sleep
S Duong-Quy, K Dang Thi Mai, N Tran Van, H Nguyen Xuan Bich, T Hua-Huy, F Chalumeau, A T Dinh-Xuan, F Soyez, F Martin
INTRODUCTION: Epidemiological studies on obstructive sleep apnoea syndrome (OSAS) in Asia, South East Asia in particular, are few. The EPSASIE study aimed to determine the prevalence of OSAS in an adult Vietnamese population and to describe its characteristics. METHODS: This is a prospective, observational, multicenter study. Nocturnal ventilatory polygraphy (PV) or polysomnography (PSG) were performed in patients having symptoms evocative of the SAS syndrome and an index of respiratory events (IER)>10/h or>25 in one hour, measured by RU Sleeping...
February 2, 2018: Revue des Maladies Respiratoires
Leeba Rezaie, Aaron D Fobian, William Vaughn McCall, Habibolah Khazaie
Paradoxical insomnia is characterized by discrepancy between subjective and objective assessments of sleep and is challenging to diagnosis and treat. Typically, polysomnographic (PSG) findings show significantly longer total sleep time than patients' report of sleep, and the difference between subjective and PSG sleep is greater than that seen in other insomnia subtypes. Subjective-objective sleep discrepancy may also present in different clinical pictures, as marked discrepancies between patients' perception of sleep and objective findings are common in a variety of medical, sleep and psychiatric disorders...
January 6, 2018: Sleep Medicine Reviews
Jia-Huan Hu, Xiao-Yu Cheng, Jin-Xin Li, Bin Xue, Jiang-Hai Tian, Jing-Sheng Hu, Bing Li
Bombyx mori is an economic insect of the Lepidoptera. Its posterior silk gland (PSG) is an important organ for fibroin synthesis. In order to study the occurrence of apoptosis in PSG and the role of PI3K/Akt signaling pathway during spinning period, changes in morphology of silk gland, expressions of fibroin components Fib-H, Fib-L and P25 and Akt, TOR2, P70S6K and S6 in PI3K/Akt pathway, expressions of apoptosis related genes caspase-3, caspase-9 and activity of caspase-3 were explored. The results showed that the morphology of silk gland dramatically degenerated; transcription of Fib-H, Fib-L, and P25 gradually declined with time; and Fib-L protein level reduced by 0...
February 5, 2018: Archives of Insect Biochemistry and Physiology
Kelly Glazer Baron, Jennifer Duffecy, Mark A Berendsen, Ivy Cheung Mason, Emily G Lattie, Natalie C Manalo
The objectives of this review were to evaluate the use of consumer-targeted wearable and mobile sleep monitoring technology, identify gaps in the literature and determine the potential for use in behavioral interventions. We undertook a scoping review of studies conducted in adult populations using consumer-targeted wearable technology or mobile devices designed to measure and/or improve sleep. After screening for inclusion/exclusion criteria, data were extracted from the articles by two co-authors. Articles included in the search were using wearable or mobile technology to estimate or evaluate sleep, published in English and conducted in adult populations...
December 20, 2017: Sleep Medicine Reviews
Jae-Wook Kim, Deok Soo Kim, Sung-Dong Kim, Sue Jean Mun, Soo-Kweon Koo, Kyu-Sup Cho
OBJECTIVE: The aims of this study were to determine the associated factors affecting the success rate of limited palatal muscle resection (LPMR), and to investigate whether drug-induced sleep endoscopy (DISE) could predict the therapeutic response to LPMR in patients with obstructive sleep apnea obstructive sleep apnea (OSA). METHODS: Twenty-one consecutive OSA patients underwent LPMR were enrolled. All patients received routine ENT examination, preoperative DISE, and polysomnography (PSG)...
January 30, 2018: Auris, Nasus, Larynx
Joseph Cheung, Chad Ruoff, Hyatt Moore, Katharine A Hagerman, Jennifer Perez, Sarada Sakamuri, Simon C Warby, Emmanuel Mignot, John Day, Jacinda Sampson
STUDY OBJECTIVES: Myotonic dystrophy type 1 (DM1) is a multisystemic disorder that involves the central nervous system (CNS). Individuals with DM1 commonly present with sleep dysregulation, including excessive daytime sleepiness and sleep-disordered breathing. We aim to characterize electroencephalogram (EEG) power spectra from nocturnal polysomnography (PSG) in patients with DM1 compared to matched controls to better understand the potential CNS sleep dysfunction in DM1. METHODS: A retrospective, case-control (1:2) chart review of patients with DM1 (n = 18) and matched controls (n = 36) referred for clinical PSG at the Stanford Sleep Center was performed...
January 30, 2018: Journal of Clinical Sleep Medicine: JCSM: Official Publication of the American Academy of Sleep Medicine
Cheng Hong, Riken Chen, Simin Qing, Ailing Kuang, HuaJing Yang, Xiaofen Su, Dongxing Zhao, Kang Wu, Nuofu Zhang
STUDY OBJECTIVES: This study was conducted to validate the NoSAS score in clinical populations and to compare it with the Berlin, STOP, and STOP-Bang questionnaires, as well as the Epworth Sleepiness Scale (ESS), in screening for sleep-disordered breathing (SDB). METHODS: A retrospective analysis was conducted of all patients aged 18 to 80 years who had completed a full-night polysomnography (PSG) at the sleep center of the First Affiliated Hospital of Guangzhou Medical University from October 2012 to November 2016...
January 30, 2018: Journal of Clinical Sleep Medicine: JCSM: Official Publication of the American Academy of Sleep Medicine
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