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https://www.readbyqxmd.com/read/28633722/characterization-of-patients-who-present-with-insomnia-is-there-room-for-asymptom-cluster-based-approach
#1
Megan R Crawford, Diana A Chirinos, Toni Iurcotta, Jack D Edinger, James K Wyatt, Rachel Manber, Jason C Ong
STUDY OBJECTIVES: This study examined empirically derived symptom cluster profiles among patients who present with insomnia using clinical data andpolysomnography. METHODS: Latent profile analysis was used to identify symptom cluster profiles of 175 individuals (63% female) with insomnia disorder based on total scoreson validated self-report instruments of daytime and nighttime symptoms (Insomnia Severity Index, Glasgow Sleep Effort Scale, Fatigue Severity Scale,Beliefs and Attitudes about Sleep, Epworth Sleepiness Scale, Pre-Sleep Arousal Scale), mean values from a 7-day sleep diary (sleep onset latency, wakeafter sleep onset, and sleep efficiency), and total sleep time derived from an in-laboratory PSG...
June 16, 2017: Journal of Clinical Sleep Medicine: JCSM: Official Publication of the American Academy of Sleep Medicine
https://www.readbyqxmd.com/read/28633091/cyclic-alternating-pattern-and-interictal-epileptiform-discharges-during-morning-sleep-after-sleep-deprivation-in-temporal-lobe-epilepsy
#2
Filippo Sean Giorgi, Michelangelo Maestri, Melania Guida, Luca Carnicelli, Lorenzo Caciagli, Raffaele Ferri, Ubaldo Bonuccelli, Enrica Bonanni
PURPOSE: Sleep deprivation (SD) increases the occurrence of interictal epileptiform discharges (IED) compared to basal EEG in temporal lobe epilepsy (TLE). In adults, EEG after SD is usually performed in the morning after SD. We aimed to evaluate whether morning sleep after SD bears additional IED-inducing effects compared with nocturnal physiological sleep, and whether changes in sleep stability (described by the cyclic alternating pattern-CAP) play a significant role. METHODS: Adult patients with TLE underwent in-lab night polysomnography (n-PSG) and, within 7days from n-PSG, they underwent also a morning EEG after night SD (SD-EEG)...
June 17, 2017: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/28626433/war-or-peace-how-the-subjective-perception-of-great-power-interdependence-shapes-preemptive-defensive-aggression
#3
Yiming Jing, Peter H Gries, Yang Li, Adam W Stivers, Nobuhiro Mifune, D M Kuhlman, Liying Bai
Why do great powers with benign intentions end up fighting each other in wars they do not seek? We utilize an incentivized, two-person "Preemptive Strike Game" (PSG) to explore how the subjective perception of great power interdependence shapes defensive aggression against persons from rival great powers. In Study 1, college students from the United States (N = 115), China (N = 106), and Japan (N = 99) made PSG decisions facing each other. This natural experiment revealed that Chinese and Japanese participants (a) made more preemptive attacks against each other and Americans than against their compatriots, and that (b) greater preexisting perceptions of bilateral competition increased intergroup attack rates...
2017: Frontiers in Psychology
https://www.readbyqxmd.com/read/28622127/prevalence-of-sleep-disordered-breathing-during-routine-electroencephalogram-eeg-a-hospital-based-descriptive-study
#4
Rajesh P Poothrikovil, Abdullah Al Asmi, Ramachandiran Nandhagopal, Mohammed Al Abri
Sleep-disordered breathing (SDB) in adults is a common condition that is associated with a range of medical problems including hypertension, cardiovascular complications, and increase of seizure frequency in susceptible individuals. Polysomnography (PSG) is considered the gold standard measure in the diagnosis of SDB. This is an observational study on the frequency of SDB in adult patients referred for routine EEG. We found that routine EEG was capable of detecting moderate to severe symptoms of SDB in 14% of adult patients (95% confidence interval = 8...
2017: Neurodiagnostic Journal
https://www.readbyqxmd.com/read/28620158/clinical-features-and-sleep-analysis-of-chinese-patients-with-fatal-familial-insomnia
#5
Liyong Wu, Hui Lu, Xianling Wang, Jia Liu, Chaoyang Huang, Jing Ye, Cuijiang Li, Jun Lu, Yuping Wang, Jianping Jia, Shuqin Zhan
This study aimed to examine clinical features, sleep, abnormal sleep-wake transition and non-sleep disturbances as well as lab tests in Chinese fatal familial insomnia (FFI) subjects. Patients with confirmed clinical and laboratory diagnosis of FFI have been retrospectively reviewed. The clinical features and the results of the complementary tests, including polysomnography (PSG), brain imaging and genetic analysis, were used. Two male and three female patients were recruited in this study. Three of the five patients had more comprehensive family medical records...
June 15, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28612268/discordant-sleep-parameters-among-actigraphy-polysomnography-and-perceived-sleep-in-patients-with-sleep-disordered-breathing-in-comparison-with-patients-with-chronic-insomnia-disorder
#6
Su Jung Choi, Miri Kang, Min Je Sung, Eun Yeon Joo
PURPOSE: Although the clinical usefulness of actigraphy (ACT) in chronic insomnia disorder (CID) is extensively investigated, the evaluation on the utility of ACT in sleep-disordered breathing (SDB) is limited and the report of comparison with perceived sleep by patients and polysomnography (PSG) is scarce. METHODS: Thirty-six patients with SDB and 30 with CID underwent PSG and ACT, and they reported perceived sleep time and latency simultaneously. Sleep parameters (total sleep time [TST], sleep onset latency [SOL], sleep efficiency, and wakefulness after sleep onset [WASO]) were compared...
June 14, 2017: Sleep & Breathing, Schlaf & Atmung
https://www.readbyqxmd.com/read/28608696/immunomodulatory-activity-of-ganoderma-atrum-polysaccharide-on-purified-t-lymphocytes-through-ca2-can-and-mapk-pathway-based-on-rna-seq
#7
Quan-Dan Xiang, Qiang Yu, Hui Wang, Ming-Ming Zhao, Shi-Yu Liu, Shaoping Nie, Ming-Yong Xie
Our previous study has demonstrated that Ganoderma atrum polysaccharide (PSG-1) has immunomodulatory activity on spleen lymphocytes. However, how PSG-1 exerts its effect on purified lymphocytes is still obscure. Thus, this study aimed to investigate the immunomodulatory activity of PSG-1 on purified T lymphocytes, and further elucidate the underlying mechanism based on RNA-seq. Our results showed that PSG-1 promoted T lymphocytes proliferation and increased the production of IL-2, IFN-γ and IL-12. Meanwhile, RNA-seq analysis found 394 differentially expressed genes...
June 13, 2017: Journal of Agricultural and Food Chemistry
https://www.readbyqxmd.com/read/28607881/a-new-predictor-for-obstructive-sleep-apnea-syndrome-monocyte-to-hdl-ratio
#8
Doğan Atan, Fatma Cemre Sazak Kundi, Kürşat Murat Özcan, Hüseyin Dere
The aim of this study was to investigate the relation of serum monocyte to serum HDL cholesterol ratio with obstructive sleep apnea syndrome (OSAS). A total of 336 patients who underwent polysomnography (PSG) were included in this study. The individuals with an apnea hypopnea index (AHI) <5/h were included in the study as controls while the patients with an AHI > 5 and excessive daytime sleepiness were included in the study as OSAS patients. OSAS patients were compared with the control group for serum monocyte count, high density lipoprotein (HDL) levels, and monocyte to HDL ratio (MHR)...
June 2017: Indian Journal of Otolaryngology and Head and Neck Surgery
https://www.readbyqxmd.com/read/28606497/validity-of-a-commercial-wearable-sleep-tracker-in-adult-insomnia-disorder-patients-and-good-sleepers
#9
Seung-Gul Kang, Jae Myeong Kang, Kwang-Pil Ko, Seon-Cheol Park, Sara Mariani, Jia Weng
OBJECTIVES: To compare the accuracy of the commercial Fitbit Flex device (FF) with polysomnography (PSG; the gold-standard method) in insomnia disorder patients and good sleepers. METHODS: Participants wore an FF and actigraph while undergoing overnight PSG. Primary outcomes were intraclass correlation coefficients (ICCs) of the total sleep time (TST) and sleep efficiency (SE), and the frequency of clinically acceptable agreement between the FF in normal mode (FFN) and PSG...
June 2017: Journal of Psychosomatic Research
https://www.readbyqxmd.com/read/28600268/slow-wave-sleep-estimation-for-healthy-subjects-and-osa-patients-using-r-r-intervals
#10
Hee Nam Yoon, Su Hwan Hwang, Jae Won Choi, Yu Jin Lee, Do Un Jeong, Kwang Suk Park
We developed an automatic slow-wave sleep (SWS) detection algorithm that can be applied to groups of healthy subjects and patients with obstructive sleep apnea (OSA). This algorithm detected SWS based on autonomic activations derived from the heart rate variations of a single sensor. An autonomic stability, which is an SWS characteristic, was evaluated and quantified using R-R intervals from an electrocardiogram (ECG). The thresholds and the heuristic rule to determine SWS were designed based on the physiological backgrounds for sleep process and distribution across the night...
June 7, 2017: IEEE Journal of Biomedical and Health Informatics
https://www.readbyqxmd.com/read/28597190/the-prevalence-of-rem-related-obstructive-sleep-apnoea-is-reduced-by-the-aasm-2012-hypopnoea-criteria
#11
Brett Duce, Antti Kulkas, Christian Langton, Juha Töyräs, Craig Hukins
PURPOSE: The variations in reported prevalence of rapid eye movement-related obstructive sleep apnoea (REM-OSA) have been attributed to different definitions, although the effect of hypopnoea criteria has not been previously investigated. METHODS: Within this retrospective study, 134 of 382 consecutive patients undertaking polysomnography (PSG) for the suspicion of OSA met the inclusion criteria. PSGs were scored using both the 2007 AASM recommended hypopnoea criteria (AASM2007Rec) and the 2012 AASM recommended hypopnoea criteria (AASM2012Rec)...
June 9, 2017: Sleep & Breathing, Schlaf & Atmung
https://www.readbyqxmd.com/read/28591236/predictors-of-success-for-mandibular-repositioning-appliance-in-obstructive-sleep-apnea-syndrome
#12
Thays Crosara Abrahão Cunha, Thais de Moura Guimarães, Teresa Cristina Barros Schultz, Fernanda Ribeiro de Almeida, Thulio Marquez Cunha, Paulo Cezar Simamoto, Lia Rita Azeredo Bittencourt
The characteristics of non-obese patients with mild to moderate Obstructive Sleep Apnea Syndrome (OSAS) who will present with a good response to Mandibular Repositioning Appliance (MRA) treatment have not yet been well established in the literature. The aim of this study is to assess whether polysomnographic (PSG), demographic, anthropometric, cephalometric, and otorhinolaryngological parameters predict MRA success in the treatment of OSAS. Forty (40) males with mild and moderate OSAS were assessed pretreatment and 2-months post-treatment after wearing an MRA...
June 5, 2017: Brazilian Oral Research
https://www.readbyqxmd.com/read/28589774/development-of-a-multiplex-qpcr-in-real-time-for-quantification-and-differential-diagnosis-of-salmonella-gallinarum-and-salmonella-pullorum
#13
Marcela da Silva Rubio, Rafael Antonio Casarin Penha Filho, Adriana Maria de Almeida, Angelo Berchieri Junior
Currently there are 2659 Salmonella serovars. The host-specific biovars Salmonella Pullorum and Salmonella Gallinarum, cause systemic infections in food-producing and wild birds. Fast diagnosis is crucial to control the dissemination in avian environments. The present work describes the development of a multiplex qPCR in real time using a low cost DNA dye (SYBr Green) to identify and quantify these biovars. Primers were chosen based on genomic regions of difference (RoD) and optimized to control dimers. Primers pSGP differentiate from other serovars and pSG and pSP differentiate biovars...
June 7, 2017: Avian Pathology: Journal of the W.V.P.A
https://www.readbyqxmd.com/read/28586093/agreement-between-jaw-muscle-activity-measurement-with-portable-single-channel-electromyography-and-polysomnography-in-children
#14
Claudia Restrepo, Frank Lobbezoo, Eduardo Castrillon, Peter Svensson, Adriana Santamaria, Claudia Alvarez, Ruben Manrique, Daniele Manfredini
BACKGROUND: Polysomnography (PSG) is the gold standard for sleep bruxism (SB) assessment. High economical costs, complex technical equipment, and unfamiliar laboratory setting limit its use in children. AIM: To determine the night-to-night variability of electromyography (EMG) episodes during a five-night recording with the GrindCare Measure (GCM), and the agreement in the assessment of masticatory muscle activity (MMA) between GCM and PSG in children. DESIGN: Forty-seven children from clinics of Universidad CES participated...
June 6, 2017: International Journal of Paediatric Dentistry
https://www.readbyqxmd.com/read/28583832/yorkie-ca-overexpression-in-the-posterior-silk-gland-improves-silk-yield-in-bombyx-mori
#15
Panli Zhang, Shumin Liu, Hong-Sheng Song, Guozheng Zhang, Qiangqiang Jia, Sheng Li
The traditional hybrid breeding techniques can no longer meet the increasing demands for silk production by the silkworm, Bombyx mori, and further improvement of the silk yield will depend on modern molecular breeding techniques. Here, we report improved silk yield in transgenic silkworms overexpressing the oncogene Yorkie(CA) specifically in the posterior silk gland (PSG). The Yorkie(CA) cDNA was ligated downstream of the hr3 enhancer and the fibroin L-chain (Fil) promoter, then inserted into a piggyBac vector for transgene...
June 2, 2017: Journal of Insect Physiology
https://www.readbyqxmd.com/read/28583511/blood-count-values-and-ratios-for-predicting-sleep-apnea-in-obese-children
#16
Ibrahim Erdim, Omer Erdur, Fatih Oghan, Fatih Mete, Mustafa Celik
OBJECTIVES: To detect whether the mean platelet volume (MPV), neutrophil-to-lymphocyte ratio (NLR), and platelet-to-lymphocyte ratio (PLR) are contributing factors in the diagnosis and severity of sleep apnea in obese children. INTRODUCTION: Obesity is a public health problem, and its prevalence increases daily. Although PSG is the gold standard test in the investigation of sleep apnea, the application of this test requires equipment, personnel, time, and cost. There is no simple laboratory test for diagnosing and determining the severity of sleep apnea...
July 2017: International Journal of Pediatric Otorhinolaryngology
https://www.readbyqxmd.com/read/28583490/polysomnography-results-versus-clinical-factors-to-predict-post-operative-respiratory-complications-following-pediatric-adenotonsillectomy
#17
John S Saur, Scott E Brietzke
OBJECTIVE: Systematically review the published literature comparing the presence of clinical features (age, BMI, co-morbidities, etc.) versus polysomnogram (PSG) results in the prediction of major post-operative respiratory complications following pediatric adenotonsillectomy (T/A) for the treatment of Obstructive Sleep Apnea Syndrome (OSAS). METHODS: A systematic review of the PUBMED and EMBASE databases was performed to identify studies containing both clinical and PSG data predicting major post-operative respiratory complications following T/A...
July 2017: International Journal of Pediatric Otorhinolaryngology
https://www.readbyqxmd.com/read/28582884/impact-of-functional-status-and-medical-comorbidities-on-tracheostomy-decannulation-in-pediatric-patients
#18
Meredith Lind, Joseph J Lopez, Tyler Merrill, Jennifer Cooper, Kris R Jatana, Leslie Justice, Mark Splaingard
To determine if medical or functional factors influence the ability of a pediatric patient with a tracheostomy to tolerate decannulation. Retrospective evaluation of patients at a tertiary Children's Hospital undergoing evaluation with capped tracheostomy polysomnogram (cPSG) for possible tracheostomy decannulation. Charts were reviewed for demographic information, functional status, cPSG characteristics, and success or failure of decannulation. Statistical analysis was performed to determine which patient factors were predictive of successful decannulation...
May 16, 2017: Journal of Pediatric Rehabilitation Medicine
https://www.readbyqxmd.com/read/28580357/impact-of-compression-stockings-vs-continuous-positive-airway-pressure-on-overnight-fluid-shift-and-obstructive-sleep-apnea-among-patients-on-hemodialysis
#19
Bruno C Silva, Roberto S S Santos, Luciano F Drager, Fernando M Coelho, Rosilene M Elias
INTRODUCTION: Obstructive sleep apnea (OSA) is common in edematous states, notably in hemodialysis patients. In this population, overnight fluid shift can play an important role on the pathogenesis of OSA. The effect of compression stockings (CS) and continuous positive airway pressure (CPAP) on fluid shift is barely known. We compared the effects of CS and CPAP on fluid dynamics in a sample of patients with OSA in hemodialysis, through a randomized crossover study. METHODS: Each participant performed polysomnography (PSG) at baseline, during CPAP titration, and after 1 week of wearing CS...
2017: Frontiers in Medicine
https://www.readbyqxmd.com/read/28576523/clinical-symptoms-that-predict-the-presence-of-obstructive-sleep-apnea
#20
Kevin C Lewis, James W Schroeder, Bushra Ayub, Bharat Bhushan
OBJECTIVE: To determine if a set of clinical symptoms can help in determining the presence and severity of OSA. SETTING: Tertiary urban pediatric hospital. METHODS: Parents of children undergoing an overnight PSG answered a 56 item questionnaire based on their child's symptoms. The responses to the questionnaire were compared between patients with different severities of OSA (s determined by PSG) and those without OSA. Responses to questionnaire were also analyzed between obese and non-obese patients...
April 2017: International Journal of Pediatric Otorhinolaryngology
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