keyword
MENU ▼
Read by QxMD icon Read
search

Vitreoretinal interface

keyword
https://www.readbyqxmd.com/read/29922890/quantitative-assessment-of-macular-contraction-and-vitreoretinal-interface-alterations-in-diabetic-macular-edema-treated-with-intravitreal-anti-vegf-injections
#1
Ebru Nevin Cetin, Önder Demirtaş, Nihal Cesur Özbakış, Gökhan Pekel
BACKGROUND: Macular contraction after anti-vascular endothelial growth factor (anti-VEGF) injections for diabetic macular edema (DME) was evaluated by documenting the displacement of macular capillary vessels and epiretinal membrane (ERM) formation. METHODS: A total of 130 eyes were included in this retrospective study. The study group consisted of 63 eyes which had intravitreal anti-VEGF injections for DME, and the control group included 67 eyes without central DME...
June 20, 2018: Graefe's Archive for Clinical and Experimental Ophthalmology
https://www.readbyqxmd.com/read/29912094/observation-of-vitreous-features-using-enhanced-vitreous-imaging-optical-coherence-tomography-in-highly-myopic-retinoschisis
#2
Minlu Song, Mengxi Shen, Yanping Zhou, Kairong Zheng, Yuanqi Zhai, Meichun Xiao, Xiaohan Wang, Fenghua Wang, Xiaodong Sun
PURPOSE: To observe features of the posterior vitreous and vitreoretinal interface in highly myopic eyes with retinoschisis using enhanced vitreous imaging optical coherence tomography. METHODS: Comprehensive ophthalmologic examination and enhanced vitreous imaging optical coherence tomography were performed in 77 eyes of 63 patients with highly myopic retinoschisis. Two different modes of spectral domain optical coherence tomography were employed to estimate retinoschisis and the posterior vitreous features in optical coherence tomography images, respectively...
June 13, 2018: Retina
https://www.readbyqxmd.com/read/29877085/metabolomics-analysis-of-human-vitreous-in-diabetic-retinopathy-and-rhegmatogenous-retinal-detachment
#3
Nathan R Haines, Niranjan Manoharan, Jeffrey L Olson, Angelo D'Alessandro, Julie A Reisz
The vitreous humor is a highly aqueous eye fluid interfacing with the retina and lens and providing shape. Its molecular composition provides a readout for the eye's physiological status. Changes in cellular metabolism underlie vitreoretinal pathologies, but despite routine surgical collection of vitreous, only limited reports of metabolism in the vitreous of human patients have been described. Here, vitreous samples from patients with rhegmatogenous retinal detachment (n=25) and proliferative diabetic retinopathy (n=9) were profiled along with control human vitreous samples (n=8) by untargeted mass spectrometry-based metabolomics...
June 7, 2018: Journal of Proteome Research
https://www.readbyqxmd.com/read/29799932/vitreous-bands-identified-by-handheld-spectral-domain-optical-coherence-tomography-among-premature-infants
#4
Emily M Zepeda, Ayesha Shariff, Thomas B Gillette, Laura Grant, Leona Ding, Kristina Tarczy-Hornoch, Michelle T Cabrera
Importance: Handheld spectral-domain optical coherence tomography (SD-OCT) can provide insights into the complex interactions occurring at the vitreoretinal interface in retinopathy of prematurity (ROP) to enhance our understanding of ROP pathology. Objective: To characterize vitreous bands in premature infants with use of handheld SD-OCT. Design, Setting, and Participants: Prospective cohort study conducted from July 7, 2015, to February 28, 2017, at 2 university-based neonatal intensive care units...
May 17, 2018: JAMA Ophthalmology
https://www.readbyqxmd.com/read/29758035/changes-in-macular-pigment-optical-density-after-membrane-peeling
#5
Mario R Romano, Gilda Cennamo, Piergiacomo Grassi, Federica Sparnelli, Davide Allegrini, Giovanni Cennamo
INTRODUCTION: To highlight the differences in macular pigment optical density (MPOD) between eyes with vitreoretinal interface syndrome and healthy control eyes, to assess the changes in MPOD in eyes treated with macular peeling, to investigate the relationships between MPOD changes and measures of retinal sensitivity such as best corrected visual acuity (BCVA) and microperimetry. METHODS: In this cross-sectional comparative study, 30 eyes affected by idiopathic epiretinal membrane (iERM, 15eyes) or full-thickness macular hole (FTMH, 15eyes) were compared with 60 eyes from 30 healthy age-matched patients...
2018: PloS One
https://www.readbyqxmd.com/read/29755819/vitreoretinal-interface-characteristics-in-eyes-with-idiopathic-macular-holes-qualitative-and-quantitative-analysis
#6
Arzu Seyhan Karatepe, Jale Menteş, E Tansu Erakgün, Filiz Afrashi, Serhad Nalçacı, Cezmi Akkın, Yeşim Ateş
Objectives: To determine the qualitative and quantitative vitreoretinal interface characteristics with spectral domain optical coherence tomography (SD-OCT) in eyes with macular hole (MH) and investigate their relation with best corrected visual acuity (BCVA) and MH duration. Materials and Methods: Sixty-one eyes of 46 consecutive patients diagnosed with idiopathic MH were included in the study. The mean age of the patients was 66.7±7.5 (51-79) years. Complete ophthalmologic examination and SD-OCT examination were performed in all eyes and MH stages were determined according to SD-OCT findings...
April 2018: Turkish Journal of Ophthalmology
https://www.readbyqxmd.com/read/29734180/influence-of-the-vitreoretinal-interface-on-the-treatment-with-anti-vegf-for-exudative-age-related-macular-degeneration
#7
Pedro Gil, João Gil, Nuno Oliveira, Inês Laíns, Eduardo Nery Rossi Camilo, Cristina Fonseca, Miguel Raimundo, Maria da Luz Cachulo, Rufino Silva
PURPOSE: To investigate the influence of the vitreoretinal interface on the outcomes of different ranibizumab regimens for exudative age-related macular degeneration. METHODS: We conducted a retrospective subanalysis of 2 prospective clinical trials. Patients were treated with ranibizumab for 12 months according to 3 different regimens: pro-re-nata (PRN), treat and extend (T&E), and monthly. Vitreoretinal interface was assessed for absence (group ON) or presence (group OFF) of posterior vitreous detachment (PVD)...
May 7, 2018: Ophthalmologica. Journal International D'ophtalmologie
https://www.readbyqxmd.com/read/29664988/peripheral-vascular-abnormalities-seen-by-ultra-widefield-fluorescein-angiography-in-adults-with-history-of-prematurity-report-of-three-cases
#8
Linda Alejandra Cernichiaro-Espinosa, Basil K Williams, María A Martínez-Castellanos, Catherin I Negron, Audina M Berrocal
Retinopathy of prematurity (ROP) may lead to late-developing complications due to the abnormal vitreoretinal interface. In this case report, three adult patients (ages 39 years, 62 years, and 64 years) with a history of prematurity underwent imaging with ultra-widefield fluorescein angiography (UWFFA). The UWFFA demonstrated late peripheral vascular hyperfluorescence in all three patients, perivascular leakage in two of the patients, hyperfluorescent foveal avascular zone in two of the patients, peripheral avascular retina in two of the patients, vasoproliferative tumor in one of the patients, peripheral neovascularization in one of the patients, and vascular anastomosis in one of the patients...
April 1, 2018: Ophthalmic Surgery, Lasers & Imaging Retina
https://www.readbyqxmd.com/read/29657974/monocular-and-binocular-visual-impairment-in-the-uk-biobank-study-prevalence-associations-and-diagnoses
#9
Martin McKibbin, Tracey M Farragher, Darren Shickle
Objective: To determine the prevalence of, associations with and diagnoses leading to mild visual impairment or worse (logMAR >0.3) in middle-aged adults in the UK Biobank study. Methods and analysis: Prevalence estimates for monocular and binocular visual impairment were determined for the UK Biobank participants with fundus photographs and spectral domain optical coherence tomography images. Associations with socioeconomic, biometric, lifestyle and medical variables were investigated for cases with visual impairment and matched controls, using multinomial logistic regression models...
2018: BMJ Open Ophthalmology
https://www.readbyqxmd.com/read/29338115/statin-use-and-vitreoretinal-surgery-findings-from-a-finnish-population-based-cohort-study
#10
Sirpa Loukovaara, Sari Sahanne, Annika Takala, Jari Haukka
PURPOSE: Vitreoretinal (VR) surgery is the third most common intraocular surgery after refractive and cataract surgery. The impact of statin therapy on VR surgery outcomes remains unclear, despite a potentially beneficial effect. We explored the association of preoperative statin therapy and the need for revitrectomy after primary vitrectomy. METHODS: Our historical, population-based, register-based, VR surgery cohort consisted of 5709 patients operated in a tertiary, academic referral hospital in Finland, during 2008-2014, covering 6...
January 16, 2018: Acta Ophthalmologica
https://www.readbyqxmd.com/read/29190243/factors-associated-with-serous-retinal-detachment-in-highly-myopic-eyes-with-vertical-oval-shaped-dome
#11
Antonio García-Ben, María J Morillo Sanchez, Ana Gonzalez Gómez, Ignacio García-Basterra, Antonio Soler García, Jose M García-Campos
PURPOSE: This study investigated factors associated with persistent serous retinal detachment in highly myopic eyes with vertical oval-shaped domes. METHODS: Twenty-eight highly myopic patients (40 eyes) with smooth macular elevations related to a vertical oval-shaped dome were recruited. Serous retinal detachment was investigated; 11 eyes had persistent submacular fluid (study group) and 29 eyes lacked submacular fluid (control group). All patients underwent complete ophthalmologic examinations, including axial-length measurement and fluorescein angiography...
November 22, 2017: Retina
https://www.readbyqxmd.com/read/29190238/longitudinal-changes-in-the-optic-nerve-head-and-retina-over-time-in-very-young-children-with-familial-exudative-vitreoretinopathy
#12
Jonghyun Lee, Mays A El-Dairi, Du Tran-Viet, Shwetha Mangalesh, Alexandria Dandridge, Kim Jiramongkolchai, Christian Viehland, Cynthia A Toth
PURPOSE: To explore vitreoretinal pathologies and their longitudinal changes visible on handheld optical coherence tomography (OCT) of young children with familial exudative vitreoretinopathy. METHODS: The authors retrospectively analyzed handheld OCT images for vitreoretinal interface and retinal abnormalities and optic nerve head (ONH) elevation. RESULTS: From 26 eyes of 16 children (mean age 32 months) with familial exudative vitreoretinopathy, 10 had ONH dragging on photographs, and in these, handheld OCT revealed temporal and anterior retinal displacement, prominent vitreopapillary adhesion or traction, and retinal nerve fiber layer thickening at ONH margins with adjacent retinal elevation...
November 22, 2017: Retina
https://www.readbyqxmd.com/read/29180844/vitreoretinal-interface-abnormalities-in-diabetic-macular-edema-and-effectiveness-of-anti-vegf-therapy-an-optical-coherence-tomography-study
#13
Alexei N Kulikov, Sergei V Sosnovskii, Roman D Berezin, Dmitrii S Maltsev, Dzhambulat H Oskanov, Nikolai A Gribanov
Purpose: To study vitreoretinal interface (VRI) abnormalities in diabetic macular edema (DME) and the influence of these on the effectiveness of intravitreal anti-vascular endothelial growth factor (VEGF) therapy. Methods: VRI status and central retinal thickness (CRT) were evaluated using line and 3D-reference scans obtained using spectral domain-optical coherence tomography RTVue-100 before and 1 month after intravitreal anti-VEGF injection (IVI). VRI status was categorized into five subgroups: normal VRI, retinal surface wrinkling associated with the eccentric epiretinal membrane (ERM), ERM involving the macular center, vitreomacular adhesion (VMA), and vitreomacular traction (VMT)...
2017: Clinical Ophthalmology
https://www.readbyqxmd.com/read/29176537/novel-surgical-technique-for-inducing-posterior-vitreous-detachment-during-pars-plana-vitrectomy-for-pediatric-patients-using-a-flexible-loop
#14
Linda A Cernichiaro-Espinosa, Audina M Berrocal
PURPOSE: Vitreoretinal surgical diseases in children are challenging because of the complex features of the vitreous, retina, and the interface between them. Posterior vitreous detachment is a crucial step during vitrectomy. To date, pharmacologic vitreolysis that liquefies the vitreous and disrupts the posterior hyaloid attachment to the retina has been studied. However, there are reports of unexplained adverse effects. We describe a case performed with a reproducible, safe and time-saving technique using a commercially available flexible loop for posterior vitreous detachment induction in a pediatric patient...
November 22, 2017: Retinal Cases & Brief Reports
https://www.readbyqxmd.com/read/29138978/-morphology-of-the-vitreoretinal-interface-in-fellow-eyes-of-patients-with-full-thickness-macular-holes
#15
J E Klaas, S Burzer, S Abraham, N Feucht, C P Lohmann, M Maier
PURPOSE: We performed a retrospective, observational clinical study to evaluate the vitreoretinal interface (VRI) in fellow eyes of patients with full thickness macular holes (FTMH) based on spectral domain optical coherence tomography (SD-OCT) examinations. METHODS: The VRI in fellow eyes of 38 patients with idiopathic FTMH, 6 of which had concomitant vitreomacular traction (VMT) and the VRI of 32 patients with FTMH with complete resolution of VMT were examined by SD-OCT for the presence of vitreomacular adhesion (VMA), VMT and the formation of FTMH, lamellar macular holes (LMH), macular pseudoholes (MPH) or epiretinal membranes (ERM)...
November 14, 2017: Der Ophthalmologe: Zeitschrift der Deutschen Ophthalmologischen Gesellschaft
https://www.readbyqxmd.com/read/29035612/enhanced-vitreous-imaging-in-uveitis
#16
Padmamalini Mahendradas, Sumukh Madhu, Ankush Kawali, Abhijit Sinha Roy, Ruchi Vala, Anand Vinekar, Rohit Shetty
PURPOSE: To study the structural visibility of the posterior vitreous cavity and vitreoretinal interface using Spectral Domain-Optical Coherence Tomography in patients with uveitis using conventional, Enhanced Depth Imaging (EDI), Combined Depth Imaging (CDI), and Enhanced Vitreous Imaging (EVI) techniques. METHODS: It was an observational cross-sectional study of 59 eyes of 33 patients between age group 12-72 years (Median 43) diagnosed as uveitis with posterior segment manifestations underwent OCT using conventional, EDI, CDI, and EVI techniques...
October 16, 2017: Ocular Immunology and Inflammation
https://www.readbyqxmd.com/read/28925755/toward-smart-design-of-retinal-drug-carriers-a-novel-bovine-retinal-explant-model-to-study-the-barrier-role-of-the-vitreoretinal-interface
#17
Karen Peynshaert, Joke Devoldere, Valérie Forster, Serge Picaud, Christian Vanhove, Stefaan C De Smedt, Katrien Remaut
Retinal gene delivery via intravitreal injection is hampered by various physiological barriers present in the eye of which the vitreoretinal (VR) interface represents the most serious hurdle. In this study, we present a retinal explant model especially designed to study the role of this interface as a barrier for the penetration of vectors into the retina. In contrast to all existing explant models, the developed model is bovine-derived and more importantly, keeps the vitreous attached to the retina at all times to guarantee an intact VR interface...
November 2017: Drug Delivery
https://www.readbyqxmd.com/read/28867131/posterior-vitreous-detachment-and-the-posterior-hyaloid-membrane
#18
Gregory S Fincham, Sean James, Carl Spickett, Michael Hollingshead, Christopher Thrasivoulou, Arabella V Poulson, Annie McNinch, Allan Richards, David Snead, Gloria A Limb, Martin P Snead
PURPOSE: Despite posterior vitreous detachment being a common ocular event affecting most individuals in an aging population, there is little consensus regarding its precise anatomic definition. We investigated the morphologic appearance and molecular composition of the posterior hyaloid membrane to determine whether the structure clinically observed enveloping the posterior vitreous surface after posterior vitreous detachment is a true basement membrane and to postulate its origin. Understanding the relationship between the vitreous (in both its attached and detached state) and the internal limiting membrane of the retina is essential to understanding the cause of rhegmatogenous retinal detachment and vitreoretinal interface disorders, as well as potential future prophylactic and treatment strategies...
February 2018: Ophthalmology
https://www.readbyqxmd.com/read/28812133/-watchful-waiting-as-a-therapeutic-principle-for-diseases-of-the-vitreoretinal-interface
#19
REVIEW
H Hoerauf, B Kirchhof
Elective surgery of the vitreoretinal interface is currently the most common reason for vitrectomy in Germany. The evaluation and correct interpretation of spectral domain optical coherence tomography (SD-OCT) images is of great importance but the indications for vitrectomy in macular surgery should be based more on patient symptoms and not only the OCT findings. Watchful waiting is highlighted as an alternative therapeutic option in individual patients. This article addresses a number of aspects and discrepancies between findings and patients' level of suffering based on binocular symptoms...
November 2017: Der Ophthalmologe: Zeitschrift der Deutschen Ophthalmologischen Gesellschaft
https://www.readbyqxmd.com/read/28791829/intravitreal-ocriplasmin-a-breakthrough-in-the-treatment-of-vitreomacular-traction
#20
REVIEW
Anna E Mec-Słomska, Joanna Adamiec-Mroczek, Ewa Kuźmicz, Marta Misiuk-Hojło
Vitreoretinal interface pathologies, such as vitreomacular traction syndrome, epiretinal membranes and macular holes are sight-threatening conditions and one of the important causes of vision defects and vision loss. To this date, vigilance with observation of how the vitreomacular traction resolves, or vitreoretinal surgery in more severe cases, were the only treatment options. Recent rapid progress in ophthalmology, especially in diagnostic and visualization techniques, provided better insight into the mechanisms taking place on the vitreoretinal surface, which enabled a more accurate selection of treatment options...
May 2017: Advances in Clinical and Experimental Medicine: Official Organ Wroclaw Medical University
keyword
keyword
38556
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"