keyword
https://read.qxmd.com/read/38546435/use-of-a-blood-biomarker-test-improves-economic-utility-in-the-evaluation-of-older-patients-presenting-with-cognitive-impairment
#1
JOURNAL ARTICLE
William J Canestaro, Randall J Bateman, David M Holtzman, Mark Monane, Joel B Braunstein
More than 16 million Americans living with cognitive impairment warrant a diagnostic evaluation to determine the cause of this disorder. The recent availability of disease-modifying therapies for Alzheimer's disease (AD) is expected to significantly drive demand for such diagnostic testing. Accurate, accessible, and affordable methods are needed. Blood biomarkers (BBMs) offer advantages over usual care amyloid positron emission tomography (PET) and cerebrospinal fluid (CSF) biomarkers in these regards. This study used a budget impact model to assess the economic utility of the PrecivityAD® blood test, a clinically validated BBM test for the evaluation of brain amyloid, a pathological hallmark of AD...
March 28, 2024: Population Health Management
https://read.qxmd.com/read/38545900/vitamin-d-deficiency-as-a-risk-factor-of-tinnitus-an-epidemiological-study
#2
JOURNAL ARTICLE
Aynur Aliyeva, Jae Sang Han, Yeonji Kim, Ji Hyung Lim, Jae Hyun Seo, Shi Nae Park
OBJECTIVES: Vitamin D deficiency as a risk factor of tinnitus has not been well known. We tried to evaluate the association between the serum 25-(OH) vitamin D levels and tinnitus among the Korean population to propose the possible role of serum vitamin D in patients with tinnitus. METHODS: This cross-sectional study investigated the potential risk factors of tinnitus in relation to serum 25(OH)D levels within the Korean population. It encompassed a health interview, nutrition assessment, and a health examination...
March 28, 2024: Annals of Otology, Rhinology, and Laryngology
https://read.qxmd.com/read/38545734/answering-the-rehabilitation-2030-call
#3
REVIEW
Emily Hillaker, Michael Bova, Jina Libby, Maria Tricarico, Patrick Andrews, Rebecca Scharf
In 2017, the World Health Organization initiated a global effort to improve rehabilitative services by 2030, with the overall goal of helping individuals with disabilities achieve maximal independence and improved well-being. Though more than 1 billion people worldwide live with a disability, a significant portion do not have access to appropriate rehabilitative services. In low-income countries, such as Zambia, where rehabilitative services are greatly lacking, disability can further exacerbate economic disparities in the context of personal, cultural, and environmental factors that limit participation in society...
March 28, 2024: PM & R: the Journal of Injury, Function, and Rehabilitation
https://read.qxmd.com/read/38545318/six-thinking-hats-model-of-learning-creative-teaching-method-in-physiotherapy-a-pilot-study
#4
JOURNAL ARTICLE
Nidhi P Vedawala, Sakshi J Thakrar, Jayesh V Thakrar, Pratik G Patel, Yash G Patel
BACKGROUND: The fast growth of science and technology in the 21st century has made it necessary for advances in many sectors, including social, economic, educational, and health. Physiotherapists must have highly developed critical thinking abilities, such as creative, critical, problem-solving, and analytical thinking, to deal with these changes. Creativity is the capacity to view, shape, and organize the world in a unique way, whereas critical thinking is the ability to think outside the box, notice parts that others cannot see, be open to new ideas, and never be afraid to attempt new things...
2024: Journal of Education and Health Promotion
https://read.qxmd.com/read/38544720/modeling-the-effects-of-formulary-exclusions-how-many-patients-could-be-affected-by-a-specific-exclusion
#5
JOURNAL ARTICLE
Anne M Sydor, Emily Bergin, Jonathan Kay, Erik Stone, Robert Popovian
Background: Medication formularies, initially designed to promote the use of cost-effective generic drugs, are now designed to maximize financial benefits for the pharmacy benefit management companies that negotiate purchase prices. In the second-largest pharmacy benefit management formulary that is publicly available, 55% of mandated substitutions are not for generic or biosimilar versions of the same active ingredient and/or formulation and may not be medically or financially beneficial to patients. Methods: We modeled the effect of excluding novel agents for atrial fibrillation/venous thromboembolism, migraine prevention, and psoriasis, which all would require substitution with a different active ingredient...
2024: Journal of health economics and outcomes research
https://read.qxmd.com/read/38543653/effects-of-salmonella-typhimurium-infection-on-the-gut-microbiota-of-cherry-valley-meat-ducks
#6
JOURNAL ARTICLE
Yue Zheng, Xue Pan, Jialei Hou, Wenchong Shi, Shuhong Sun, Mengze Song, Zheng Gao
Salmonella infection causes serious economic losses, threatens food safety, and is one of the most important diseases threatening meat duck farming. The gut microbiome is critical in providing resistance against colonization by exogenous microorganisms. Studying the relationship between Salmonella and gut microbiota can help us better understand the threat of the pathogenic mechanism of Salmonella and provide a more scientific theoretical basis for its prevention and treatment. This study uses Salmonella Typhimurium as the research object and Cherry Valley meat duck as the model with which to study the impact of Salmonella infection on ducks...
March 18, 2024: Microorganisms
https://read.qxmd.com/read/38543629/yeast-based-screening-of-anti-viral-molecules
#7
REVIEW
Vartika Srivastava, Ravinder Kumar, Aijaz Ahmad
Viruses are minuscule infectious agents that reproduce exclusively within the living cells of an organism and are present in almost every ecosystem. Their continuous interaction with humans poses a significant threat to the survival and well-being of everyone. Apart from the common cold or seasonal influenza, viruses are also responsible for several important diseases such as polio, rabies, smallpox, and most recently COVID-19. Besides the loss of life and long-term health-related issues, clinical viral infections have significant economic and social impacts...
March 14, 2024: Microorganisms
https://read.qxmd.com/read/38543594/advances-in-the-effects-of-dietary-macronutrients-on-the-gut-microbiota-of-tilapia-oreochromis-spp
#8
REVIEW
Weihao Ou, Zihe Guo, Ying Pan, Kai Huang, Yanqun Ma, Zhibiao Qin
The homeostasis of the intestinal microbiota of fish is beneficial to fish health, while food can affect the intestinal microbiota. Tilapia ( Oreochromis spp.) has great economic value and is a good model to use in studying the digestion and absorption of nutrients. Furthermore, at present, due to a high demand and high price of high-quality feed raw materials, the nutritional composition of aquafeeds has been changing dynamically. There has yet to be a comprehensive review of research conducted on the influences of dietary macronutrients (proteins, lipids, and carbohydrates) on the tilapia intestinal microbiota...
March 8, 2024: Microorganisms
https://read.qxmd.com/read/38542716/effect-of-a-multicomponent-food-pantry-intervention-in-client-subgroups
#9
JOURNAL ARTICLE
Jenny Jia, Maria F Gombi-Vaca, Christina Bliss Barsness, Hikaru Peterson, Rebekah Pratt, Julian Wolfson, Caitlin E Caspi
Nutrition promotion programs may have varying effects and influence health disparities. SuperShelf promotes healthy choices in food pantries through inventory changes and nudge implementation (e.g., choice architecture). This secondary analysis of the SuperShelf cluster-randomized trial assessed whether the effect of SuperShelf on client diet quality differed by equity characteristics. English-, Spanish-, or Somali-speaking adult clients from 11 food pantries in Minnesota were included (N = 193). We measured change in diet quality by the Healthy Eating Index 2015 (HEI-2015; maximum score 100) using up to two 24 h dietary recalls from pre-intervention and post-intervention periods...
March 12, 2024: Nutrients
https://read.qxmd.com/read/38542692/food-choice-and-dietary-perspectives-of-young-urban-black-pregnant-women-a-focus-group-study
#10
JOURNAL ARTICLE
Tristesse Catessa Jasmin Burton, Natasha Crooks, Lacey Pezley, Nefertiti OjiNjideka Hemphill, Yanqiao Li, Arissara Sawatpanich, Vanessa Farrow, Katherine Erbe, Nicollette Kessee, Luecendia Reed, Lisa Tussing-Humphreys, Mary Dawn Koenig
Black pregnant women in Chicago are disproportionately affected by maternal morbidity and mortality and are more likely to reside in neighborhoods that experience greater economic hardships and food apartheid than any other race/ethnicity. Addressing social determinants of health such as structural inequities, economic environment, and food apartheid issues may provide insights into eliminating Black maternal morbidity and mortality disparities. This study explores food choice determinants and dietary perspectives of young, urban, Black pregnant women...
March 9, 2024: Nutrients
https://read.qxmd.com/read/38541738/gut-microbiota-modulators-based-on-polyphenols-extracted-from-winery-by-products-and-their-applications-in-the-nutraceutical-industry
#11
REVIEW
Laura-Dorina Dinu, Emanuel Vamanu
Vine-growing for the production of wine is one of the oldest and most important agricultural activities worldwide, but the winemaking process leads to vast amounts of waste. Viticulture and vinification by-products have many bioactive molecules, including polyphenols, prebiotic fibers, organic acids, and minerals. While research on the specific human health effects of grapevine residues (pomace, seeds, barks, stalks, canes, and leaves) is still ongoing, the available data suggest the potential to positively modulate the normal and dysbiotic gut microbiota (GM) using polyphenol-rich extracts obtained from winery by-products...
March 20, 2024: Life
https://read.qxmd.com/read/38541298/the-healthcare-and-societal-costs-of-familial-intellectual-disability
#12
JOURNAL ARTICLE
Deborah Schofield, Rupendra Shrestha, Owen Tan, Katherine Lim, Radhika Rajkumar, Sarah West, Jackie Boyle, Lucinda Murray, Melanie Leffler, Louise Christie, Morgan Rice, Natalie Hart, Jinjing Li, Robert Tanton, Tony Roscioli, Mike Field
Most of the studies on the cost of intellectual disability are limited to a healthcare perspective or cohorts composed of individuals where the etiology of the condition is a mixture of genetic and non-genetic factors. When used in policy development, these can impact the decisions made on the optimal allocation of resources. In our study, we have developed a static microsimulation model to estimate the healthcare, societal, and lifetime cost of individuals with familial intellectual disability, an inheritable form of the condition, to families and government...
March 4, 2024: International Journal of Environmental Research and Public Health
https://read.qxmd.com/read/38540563/what-are-the-economic-arguments-for-mandating-lgbt-health-training-for-healthcare-providers-an-economic-evaluation-of-the-impacts-of-lgbt-health-training-on-cervical-screening
#13
JOURNAL ARTICLE
Saima Bashir, William Whittaker, Catherine Meads
Background : Equitable access to healthcare is a priority of many healthcare systems, aiming to ensure access is driven by need and not minority groups such as those defined by sexual orientation. However, there are healthcare areas where inequity in access across sexual orientation groups is found that are not justified based on need. Mandated LGBTQ+-specific training of the healthcare workforce may help address some barriers of access for these groups. The study aims to understand the potential economic implications for mandated LGBTQ+-specific healthcare training on the healthcare system in England, UK to inform commissioning of training provision...
March 21, 2024: Behavioral Sciences
https://read.qxmd.com/read/38540462/influence-of-co-parenting-on-parental-burnout-a-moderated-mediation-model
#14
JOURNAL ARTICLE
Qin Zhang, Mei Zhao
Adolescence has always been regarded as a period of rapid psychological and behavioral change. Adolescents are subject to more difficult behaviors, and those difficult behaviors have a great impact on co-parenting and parenting burnout. In order to reveal the relationship between these factors, this study investigated the mediating effect of difficult adolescent behaviors on that relationship by constructing a theoretical model and examined the moderating effect of family functioning. In order to provide a scientific basis for preventing and intervening in adolescents' problematic behaviors and improving parents' parenting burnout, we conducted a study on the parents of 1638 teenagers in a junior high school in Huanggang City, China in May 2023, with a questionnaire filled out by the parents...
February 22, 2024: Behavioral Sciences
https://read.qxmd.com/read/38539962/udder-claw-and-reproductive-health-in-genomic-selection-of-the-czech-holstein
#15
JOURNAL ARTICLE
Zuzana Krupová, Eva Kašná, Ludmila Zavadilová, Emil Krupa, Jiří Bauer, Marie Wolfová
The aim of this study was to construct an enhanced selection index using the genomic and economic parameters of new health disorders and current production and functional traits. Genomic evaluation for the incidence of clinical mastitis (CM), three claw disease traits, retained placenta (RET), metritis (MET), and cystic ovaries (CYS) was performed using linear animal models based on producer-recorded data. Good correlations among the health disorders were found, and their heritability estimates did not exceed 7%...
March 11, 2024: Animals: An Open Access Journal From MDPI
https://read.qxmd.com/read/38539220/trends-in-household-out-of-pocket-health-expenditures-and-their-underlying-determinants-explaining-variations-within-african-regional-economic-communities-from-countries-panel-data
#16
JOURNAL ARTICLE
Nicholas Ngepah, Ariane Ephemia Ndzignat Mouteyica
BACKGROUND: The persistently high out-of-pocket health spending (OOPHE) in Africa raise significant concern about the prospect of reaching SDG health targets and UHC. The study examines the convergence hypothesis of OOPHE in 40 African countries from 2000 to 2019. METHODS: We exploit the <mml:math xmlns:mml="https://www.w3.org/1998/Math/MathML"> <mml:mrow><mml:mrow><mml:mtext>log</mml:mtext> <mml:mspace/></mml:mrow> <mml:mi>t</mml:mi></mml:mrow> </mml:math> , club clustering, and merging methods on a panel of dataset obtained from the World Development Indicators, the World Governance Indicators, and the World Health Organization...
March 28, 2024: Globalization and Health
https://read.qxmd.com/read/38539187/benchmark-findings-from-a-veteran-electronic-patient-reported-outcomes-evaluation-from-a-chronic-pain-management-telehealth-program
#17
JOURNAL ARTICLE
Jolie N Haun, Christopher A Fowler, Bridget M Smith, Lishan Cao, Kevin T Stroupe, William A Lapcevic, Michael S Saenger, Rachel C Benzinger, Dustin D French
BACKGROUND: Chronic pain is a leading cause of disability and negatively impacts biological/physical, psychological, and social aspects of life resulting in significant pain interference or disability. This project was part of a longitudinal mixed-methods implementation evaluation of the TelePain-Empower Veterans Program (EVP), a non-pharmacological chronic pain intervention. The purpose of this quality management project was to examine electronic patient-reported outcome measures (ePROs) including primary pain-related (intensity, interference, catastrophizing, kinesiophobia) and secondary outcomes (physical, psychological, acceptance, social) to determine TelePain-EVP effectiveness...
March 28, 2024: BMC Health Services Research
https://read.qxmd.com/read/38537575/the-global-prevalence-of-trichuris-trichiura-infection-in-humans-2010-2023-a-systematic-review-and-meta-analysis
#18
REVIEW
Hamed Behniafar, Mahdi Sepidarkish, Mehrdad Jafari Tadi, Soghra Valizadeh, Mostafa Gholamrezaei, Faezeh Hamidi, Hossein Pazoki, Faezeh Alizadeh, Nazanin Kianifard, Morteza Sheikhi Nooshabadi, Kimia Bagheri, Faezeh Hemmati, Taha Hemmati, Neda Ahmazadeh Tori, Abdelmonem Siddiq, Ali Rostami
This systematic review and meta-analysis study aimed to evaluate global Trichuris infection prevalence, assessing progress towards the WHO's 2030 target. We searched international databases from 2010-2023, categorizing data by regions and socio-economic variables using a random-effects model. Analyzing 757 articles covering 7154,842 individuals from 78 countries, the study found a pooled global prevalence of (6.64-7.57%), with the highest rates in the Caribbean (21.72%; 8.90-38.18%) and South-East Asia (20...
March 5, 2024: Journal of Infection and Public Health
https://read.qxmd.com/read/38536860/cost-effectiveness-of-a-pediatric-operating-room-installation-in-sub-saharan-africa
#19
JOURNAL ARTICLE
Ava Yap, Salamatu I Halid, Nancy Ukwu, Ruth Laverde, Paul Park, Greg Klazura, Emma Bryce, Maija Cheung, Elliot Marseille, Doruk Ozgediz, Emmanuel A Ameh
The unmet need for pediatric surgery imposes enormous health and economic consequences globally, predominantly shouldered by Sub-Saharan Africa (SSA) where children comprise almost half of the population. Lack of knowledge about the economic impact of improving pediatric surgical infrastructure in SSA inhibits the informed allocation of limited resources towards the most cost-effective interventions to bolster global surgery for children. We assessed the cost-effectiveness of installing and running two dedicated pediatric operating rooms (ORs) in a hospital in Nigeria with a pre-existing pediatric surgical service by constructing a decision tree model of pediatric surgical delivery at this facility over a year, comparing scenarios before and after the installation of the ORs, which were funded philanthropically...
2024: PLOS Glob Public Health
https://read.qxmd.com/read/38536634/the-introduction-of-a-minimum-wage-in-germany-and-the-effects-on-physical-activity-participation
#20
JOURNAL ARTICLE
Sören Dallmeyer, Christoph Breuer
The relationship between income and physical activity has been extensively studied. This paper utilizes the introduction of the minimum wage in Germany in 2015 as a quasi-experiment to determine the causal effect of minimum wages on the frequency of physical activity participation. Employing survey data from the German Socio-Economic Panel between 2013 and 2017, regression-adjusted difference-in-difference models combined with matching techniques are estimated. Our findings reveal a notable negative effect immediately after the minimum wage implementation on physical activity frequency...
March 27, 2024: International Journal of Health Economics and Management
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