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Health economic modeling

Krista L Haines, Suresh Agarwal, Hee Soo Jung
INTRODUCTION: Asian-Americans and Pacific Islanders are often considered as a uniform group when examining race in health outcomes. However, the generally favorable economic outcomes in this group belie significant socioeconomic variance between its heterogeneous subgroups. This study evaluates the impact of socioeconomic status on the health outcomes of Asian trauma patients. METHODS: From 2012 to 2015, 52,704 Asians who presented to trauma centers were registered with the National Trauma Data Bank with known disposition...
August 2018: Journal of Surgical Research
Min Su, Yafei Si, Zhongliang Zhou, Chi Shen, Wanyue Dong, Xiaojing Fan, Xiao Wang, Xiaolin Wei
BACKGROUND: Hypertension has become a global health challenge given its high prevalence and but low awareness and detection. Whether the actual prevalence of hypertension has been estimated is important, especially for the poor. This study aimed to measure tested prevalence and self-reported prevalence of hypertension and compare the inequity between them in China. METHODS: Data were derived from China Health and Nutrition Survey (CHNS) conducted in 2011. By using the multistage, stratified, random sampling method, 12,168 respondents aged 18 or older were identified for analysis...
June 15, 2018: International Journal for Equity in Health
Adrienne M Gilligan, David S Alberts, Denise J Roe, Grant H Skrepnek
PURPOSE: To evaluate the impact of cancer upon a patient's depletion of net worth and incursion of debt in the U.S. METHODS: This longitudinal study used the Health and Retirement Study (HRS) from 1998-2014. Persons ≥50 years with newly-diagnosed malignancies were included, excluding minor skin cancers. Multivariable generalized linear models were employed to assess changes in net worth and debt (consumer, mortgage, home equity) at two-and four-years following diagnosis (Year+2 , Year+4 ) after controlling for demographic and clinically-related variables, cancer-specific attributes, economic factors, and mortality...
June 12, 2018: American Journal of Medicine
Uri Ladabaum, Ajitha Mannalithara, Joel V Brill, Zachary Levin, M Kate Bundorf
OBJECTIVES: Most cost-effectiveness analyses of colorectal cancer (CRC) screening assume Medicare payment rates and a lifetime horizon. Our aims were to examine the implications of differential payment levels and time horizons for commercial insurers vs. Medicare on the cost-effectiveness of CRC screening. METHODS: We used our validated Markov cohort simulation of CRC screening in the average risk US population to examine CRC screening at ages 50-64 under commercial insurance, and at ages 65-80 under Medicare, using a health-care sector perspective...
June 15, 2018: American Journal of Gastroenterology
Linda Hollén, Rosemary Greenwood, Rebecca Kandiyali, Jenny Ingram, Chris Foy, Susan George, Sandra Mulligan, Francesca Spickett-Jones, Simon Booth, Anthony Sack, Alan Emond, Ken Dunn, Amber Young
OBJECTIVES: To evaluate the impact of low-friction (LF) bedding on graft loss in an acute burn care setting, and to examine the feasibility and costs of using LF bedding compared with standard care. DESIGN: Proof of concept before and after study with feasibility of delivering the intervention. SETTING: Three burns services within two UK hospital trusts. PARTICIPANTS: Inclusion criteria were patients older than 4 weeks, who received a skin graft after burn injury and were admitted overnight...
June 14, 2018: BMJ Open
Sharalyn Steenson, Hilal Özcebe, Umut Arslan, Hande Konşuk Ünlü, Özgür M Araz, Mahmut Yardim, Sarp Üner, Nazmi Bilir, Terry T-K Huang
BACKGROUND: Childhood obesity rates have been rising rapidly in developing countries. A better understanding of the risk factors and social context is necessary to inform public health interventions and policies. This paper describes the validation of several measurement scales for use in Turkey, which relate to child and parent perceptions of physical activity (PA) and enablers and barriers of physical activity in the home environment. METHOD: The aim of this study was to assess the validity and reliability of several measurement scales in Turkey using a population sample across three socio-economic strata in the Turkish capital, Ankara...
2018: PloS One
Hanen Samouda, Maria Ruiz-Castell, Valery Bocquet, Andrea Kuemmerle, Anna Chioti, Frédéric Dadoun, Ngianga-Bakwin Kandala, Saverio Stranges
The analyses of geographic variations in the prevalence of major chronic conditions, such as overweight and obesity, are an important public health tool to identify "hot spots" and inform allocation of funding for policy and health promotion campaigns, yet rarely performed. Here we aimed at exploring, for the first time in Luxembourg, potential geographic patterns in overweight/obesity prevalence in the country, adjusted for several demographic, socioeconomic, behavioural and health status characteristics...
2018: PloS One
Elsa A Healy, Bonnie N Kaiser, Eve S Puffer
INTRODUCTION: Youth in low- and middle-income countries (LMICs) are at increased risk for poor mental health due to economic and social disadvantage. Interventions that strengthen families may equip children and adolescents with the supports and resources to fulfill their potential and buffer them from future stressors and adversity. Due to human resource constraints, task-sharing-delivery of interventions by nonspecialists-may be an effective strategy to facilitate the dissemination of mental health interventions in low resource contexts...
June 2018: Families, Systems & Health: the Journal of Collaborative Family Healthcare
Xiang-Ming Xu, Emma Vestesson, Lizz Paley, Anita Desikan, David Wonderling, Alex Hoffman, Charles DA Wolfe, Anthony G Rudd, Benjamin D Bray
Introduction: Stroke registries are used in many settings to measure stroke treatment and outcomes, but rarely include data on health economic outcomes. We aimed to extend the Sentinel Stroke National Audit Programme registry of England, Wales and Northern Ireland to derive and report patient-level estimates of the cost of stroke care. Methods: An individual patient simulation model was built to estimate health and social care costs at one and five years after stroke, and the cost-benefits of thrombolysis and early supported discharge...
March 2018: European stroke journal
F Trentini, P Poletti, F Baldacchino, A Drago, F Montarsi, G Capelli, A Rizzoli, R Rosà, C Rizzo, S Merler, A Melegaro
The arrival of infected travelers from endemic regions can trigger sustained autochthonous transmission of mosquito-borne pathogens in Europe. In 2007 a Chikungunya outbreak was observed in central Italy, mostly affecting two villages characterised by a high density of Aedes albopictus. The outbreak was mitigated through intervention strategies reducing the mosquito abundance. Ten years later, in 2017, sustained Chikungunya transmission was documented in both central and southern Italy. The proposed analysis identifies suitable reactive measures for the containment and mitigation of future epidemics by combining epidemiological modeling with a health economic approach, considering different arrival times of imported infections and possible delays in the notification of cases...
June 13, 2018: Scientific Reports
Michael Zoorob
OBJECTIVE: Economic policies can have unintended consequences on population health. In recent years, many states in the USA have passed 'right to work' (RTW) laws which weaken labour unions. The effect of these laws on occupational health remains unexplored. This study fills this gap by analysing the effect of RTW on occupational fatalities through its effect on unionisation. METHODS: Two-way fixed effects regression models are used to estimate the effect of unionisation on occupational mortality per 100 000 workers, controlling for state policy liberalism and workforce composition over the period 1992-2016...
June 13, 2018: Occupational and Environmental Medicine
Hassan Haghparast-Bidgoli, Giulia Rinaldi, Hossein Shahnavazi, Hamid Bouraghi, Aliasghar A Kiadaliri
BACKGROUND: Suicide is a major global health problem, especially among youth. Suicide is known to be associated with a variety of social, economic, political and religious factors, vary across geographical and cultural regions. The current study aimed to investigate the effects of socioeconomic factors on suicide mortality rate across different regions in Iran. METHODS: The data on distribution of population and socio-economic factors (such as unemployment rate, divorce rate, urbanization rate, average household expenditure etc...
June 14, 2018: International Journal for Equity in Health
Anne-France Viet, Stéphane Krebs, Olivier Rat-Aspert, Laurent Jeanpierre, Catherine Belloc, Pauline Ezanno
The effectiveness of infectious disease control depends on the ability of health managers to act in a coordinated way. However, with regards to non-notifiable animal diseases, farmers individually decide whether or not to implement control measures, leading to positive and negative externalities for connected farms and possibly impairing disease control at a regional scale. Our objective was to facilitate the identification of optimal incentive schemes at a collective level, adaptive to the epidemiological situation, and minimizing the economic costs due to a disease and its control...
2018: PloS One
Chiranjeev Sanyal, Paul Stolee, Don Juzwishin, Don Husereau
BACKGROUND: Innovations in eHealth technologies have the potential to help older adults live independently, maintain their quality of life, and to reduce their health system dependency and health care expenditure. The objective of this study was to systematically review and appraise the quality of cost-effectiveness or utility studies assessing eHealth technologies in study populations involving older adults. METHODS: We systematically searched multiple databases (MEDLINE, EMBASE, CINAHL, NHS EED, and PsycINFO) for peer-reviewed studies published in English from 2000 to 2016 that examined cost-effectiveness (or utility) of eHealth technologies...
2018: PloS One
Thor Gamst-Klaussen, Admassu N Lamu, Gang Chen, Jan Abel Olsen
BACKGROUND: Many clinical studies including mental health interventions do not use a health state utility instrument, which is essential for producing quality-adjusted life years. In the absence of such utility instrument, mapping algorithms can be applied to estimate utilities from a disease-specific instrument.AimsWe aim to develop mapping algorithms from two widely used depression scales; the Depression Anxiety Stress Scales (DASS-21) and the Kessler Psychological Distress Scale (K-10), onto the most widely used health state utility instrument, the EQ-5D-5L, using eight country-specific value sets...
July 2018: BJPsych Open
Lindsay Claxton, Matthew Taylor, Arif Soonasra, Jeffrey A Bourret, Robert A Gerber
BACKGROUND: Treatment cycling with biologic disease-modifying anti-rheumatic drugs, such as tumor necrosis factor inhibitors (TNFi), is common among patients with rheumatoid arthritis (RA) and can result in reduced clinical efficacy and increased economic burden. Tofacitinib is an oral Janus kinase inhibitor for the treatment of RA. OBJECTIVE: To evaluate and compare the economic effect of tofacitinib 5 mg twice daily (BID) treatment directly after methotrexate (MTX) in the MTX-inadequate responder population, or after MTX and 1 TNFi (adalimumab [ADA] or etanercept [ETN]) or 2 TNFi (ADA and ETN) in TNF-inadequate responder patients with RA, from a U...
June 13, 2018: Journal of Managed Care & Specialty Pharmacy
Rodolfo Castro, Louise Crathorne, Hugo Perazzo, Julio Silva, Chris Cooper, Jo Varley-Campbell, Daniel Savignon Marinho, Marcela Haasova, Valdilea G Veloso, Rob Anderson, Chris Hyde
BACKGROUND: Decisions about which subgroup of chronic hepatitis C (CHC) patients should be treated with direct acting anti-viral agents (DAAs) have economic importance due to high drug prices. Treat-all DAA strategies for CHC have gained acceptance despite high drug acquisition costs. However, there are also costs associated with the surveillance of CHC to determine a subgroup of patients with significant impairment. The aim of this systematic review was to describe the modelling methods used and summarise results in cost-effectiveness analyses (CEAs) of both CHC treatment with DAAs and surveillance of liver disease...
June 13, 2018: BMC Medical Research Methodology
Zanfina Ademi, Yuki Tomonaga, Joris van Stiphout, Dominik Glinz, Viktoria Gloy, Heike Raatz, Heiner C Bucher, Matthias Schwenkglenks
OBJECTIVES: The aims of this study were to (a) identify and assess the quality of reporting of published cost-effectiveness studies of bariatric surgery, (b) assess their transferability to Switzerland, and (c) adapt transferable cost-effectiveness results to Switzerland. METHODS: A systematic literature search was performed in Medline, Embase and other databases. Two reviewers independently undertook screening, extraction, assessment of reporting quality utilising the Consolidated Health Economic Evaluation Reporting Standards, transferability, adaptation of cost data and recalculation of cost-effectiveness results...
June 12, 2018: Swiss Medical Weekly
Èrica Martínez-Solanas, María López-Ruiz, Gregory A Wellenius, Antonio Gasparrini, Jordi Sunyer, Fernando G Benavides, Xavier Basagaña
BACKGROUND: Extreme cold and heat have been linked to an increased risk of occupational injuries. However, the evidence is still limited to a small number of studies of people with relatively few injuries and with a limited geographic extent, and the corresponding economic effect has not been studied in detail. OBJECTIVES: We assessed the relationship between ambient temperatures and occupational injuries in Spain along with its economic effect. METHODS: The daily number of occupational injuries that caused at least one day of leave and the daily maximum temperature were obtained for each Spanish province for the years 1994-2013...
June 2018: Environmental Health Perspectives
Vered Slonim-Nevo, Orly Sarid, Michael Friger, Doron Schwartz, Ruslan Sergienko, Avihu Pereg, Hillel Vardi, Terri Singer, Elena Chernin, Dan Greenberg, Shmuel Odes
Background: Psychological distress increases morbidity in ulcerative colitis (UC) and Crohn's disease (CD). We examined whether social support is associated with distress and disease activity. Methods : There were 110 UC and 147 CD patients who completed sociodemography, economic status, disease activity (UC: Patient Simple Clinical Colitis Activity Index (P-SCCAI), CD: Patient Harvey-Bradshaw Index . (P-HBI), Multidimensional Scale of Perceived Social Support (MSPSS), Brief Symptom Inventory with Global Severity Index (GSI) of psychological distress, and 2 health-related quality-of-life scales (SF-36 Physical Health and Mental Health, and Short Inflammatory Bowel Disease Questionnaire (SIBDQ)...
June 8, 2018: Inflammatory Bowel Diseases
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