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Epidemiological methods

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https://www.readbyqxmd.com/read/29474648/an-integrated-quantitative-index-for-measuring-chronic-multisite-pain-the-multiple-areas-of-pain-map-study
#1
Mark S Wallace, James North, Eric J Grigsby, Leonardo Kapural, Mahendra R Sanapati, Stephen G Smith, Channing Willoughby, Patrick J McIntyre, Steven P Cohen, Richard M Rosenthal, Shaik Ahmed, Ricardo Vallejo, Farshad M Ahadian, Thomas L Yearwood, Allen W Burton, Edward J Frankoski, Jai Shetake, Sherry Lin, Brad Hershey, Benjamin Rogers, Nitzan Mekel-Bobrov
Objective: Despite the high prevalence of chronic multisite pain, there is little consensus on methods to characterize it. Commonly used assessments report only one dimension of pain, that is, intensity, thus ignoring the spatial aspect of pain. We developed a novel pain quantification index, the Integrated Pain Quantification Index (IPQI), on a scale of 0 to 1 that integrates multiple distinct pain measures into a single value, thus representing multidimensional pain information with a single value...
February 21, 2018: Pain Medicine: the Official Journal of the American Academy of Pain Medicine
https://www.readbyqxmd.com/read/29473843/prevalence-of-oral-clefts-among-live-births-in-gansu-province-china
#2
Mengying Wang, Ruogu Meng, Zhuqing Wang, Dongjing Liu, Hui Huang, Chuyun Kang, Hongtian Li, Tao Wu, Siyan Zhan
Background: Oral clefts (OCs) are common human birth defects. Children with OCs in underdeveloped regions are more likely to suffer from poverty and hardship in their future lives. Here, we attempted to estimate the prevalence of OCs among live births in Gansu Province in 2008 to understand the epidemiologic pattern of the disease. Methods: A cross-sectional study was conducted from January 2008 to December 2008 in Gansu Province. The live births delivered between January and December 2008 with OCs were investigated through face-to-face questionnaire survey...
February 23, 2018: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/29472834/real-world-data-in-health-technology-assessments-in-kidney-transplants-in-germany-use-of-routinely-collected-data-to-address-epidemiologic-questions-in-kidney-transplants-in-the-amnog-process-in-germany
#3
Kirsten H Herrmann, Ulf Meier-Kriesche, Aljoscha S Neubauer
Introduction: It is discussed whether real world data can be used in health technology assessment. Following it is of interest whether routinely collected data for quality assurance (QA) in the hospital sector is feasible to address epidemiologic questions in kidney transplantation in the AMNOG process in Germany. Objectives: To investigate the proportion of kidney transplants classified as from so-called standard criteria donors (SCD) and from expanded criteria donors (ECD) in Germany and to study the age distribution...
2018: German Medical Science: GMS E-journal
https://www.readbyqxmd.com/read/29472764/an-alternative-approach-for-evaluating-the-phenotypic-virulence-factors-of-pathogenic-escherichia-coli
#4
Kamelia M Osman, Ashgan M Hessain, Usama H Abo-Shama, Zeinab M Girh, Saleh A Kabli, Hassan A Hemeg, Ihab M Moussa
Escherichia coli is a recognized zoonotic food-borne pathogen; however, the use of polymerase chain reaction (PCR) in the underdeveloped countries to differentiate pathogenic from non-pathogenic E. coli is a problematic issue. Our grail was to assess the phenotypic virulence markers motility, hemolysin, congo red agar, embryo lethality assay and serum resistance for pathogenic E. coli (PEC) correlated to PCR tests which is currently used world-wide to evaluate the PEC. The 448 strains of Escherichia coli that were isolated from different sources, were characterized for phenotypic virulence factors such as motility, hemolysin, Congo red binding, Embryo Lethality assay (ELA) and serum resistance, as well as antibiotic susceptibility using disc diffusion method to 23 antibiotics ...
February 2018: Saudi Journal of Biological Sciences
https://www.readbyqxmd.com/read/29471623/monitoring-human-enteric-viruses-in-wastewater-and-relevance-to-infections-encountered-in-the-clinical-setting-a-one-year-experiment-in-central-france-2014-to-2015
#5
Maxime Bisseux, Jonathan Colombet, Audrey Mirand, Anne-Marie Roque-Afonso, Florence Abravanel, Jacques Izopet, Christine Archimbaud, Hélène Peigue-Lafeuille, Didier Debroas, Jean-Luc Bailly, Cécile Henquell
BackgroundHuman enteric viruses are resistant in the environment and transmitted via the faecal-oral route. Viral shedding in wastewater gives the opportunity to track emerging pathogens and study the epidemiology of enteric infectious diseases in the community. Aim: The aim of this study was to monitor the circulation of enteric viruses in the population of the Clermont-Ferrand area (France) by analysis of urban wastewaters. Methods: Raw and treated wastewaters were collected between October 2014 and October 2015 and concentrated by a two-step protocol using tangential flow ultrafiltration and polyethylene glycol precipitation...
February 2018: Euro Surveillance: Bulletin Européen sur les Maladies Transmissibles, European Communicable Disease Bulletin
https://www.readbyqxmd.com/read/29471102/high-fructose-diet-induced-metabolic-syndrome-pathophysiological-mechanism-and-treatment-by-traditional-chinese-medicine
#6
REVIEW
Ying Pan, Ling-Dong Kong
Fructose is a natural monosaccharide broadly used in modern society. Over the past few decades, epidemiological studies have demonstrated that high fructose intake is an etiological factor of metabolic syndrome (MetS). This review highlights research advances on fructose-induced MetS, especially the underlying pathophysiological mechanism as well as pharmacotherapy by traditional Chinese medicine (TCM), using the PubMed, Web of science, China National Knowledge Infrastructure, China Science and Technology Journal and Wanfang Data...
February 19, 2018: Pharmacological Research: the Official Journal of the Italian Pharmacological Society
https://www.readbyqxmd.com/read/29469532/-a-comparison-of-knowledge-awareness-rates-and-influencing-factors-of-clonorchiasis-among-residents-in-4-counties-cities-of-hunan-province
#7
Wei Xuan-Dong, Wei Mo, Lv Yuan, Yi Shang-Hui, Liu Tao-Cheng, Luo Chun-Xiang, Zha Wen-Ting, Luo Qing-Hong
OBJECTIVE: To understand the status of knowledge awareness rates and influencing factors of clonorchiasis among the residents in 4 counties (cities) of Hunan Province, so as to provide the references for formulating the prevention and control strategy of clonorchiasis in the province. METHODS: A total of 1 224 subjects were selected by the multi-stage cluster sampling method and investigated with questionnaires and face-to-face interviews. RESULTS: The clonorchiasis knowledge awareness rates of the residents were 15...
May 5, 2017: Zhongguo Xue Xi Chong Bing Fang Zhi za Zhi, Chinese Journal of Schistosomiasis Control
https://www.readbyqxmd.com/read/29469448/-trends-of-soil-transmitted-nematode-infections-in-jiangxi-province
#8
Zeng Xiao-Jun, Jiang Wei-Sheng, Xie Shu-Ying, Ge Jun, Li Zhao-Jun, Hang Chun-Qin, Liu Yue-Min, Yi Fang-Yu, Chen Hong-Gen
OBJECTIVE: To analyze the status and trends of soil-transmitted nematode infections in Jiangxi Province from 1989 to 2014, so as to provide the evidence for generating the strategy of soil-transmitted nematode prevention and control. METHODS: The data of three epidemiological surveys on human parasitic diseases (in 1989, 2002 and 2014) were classified and analyzed. The stool examination by Kato-Katz's thick smear method was adopted for the investigation of soil-transmitted nematode infections...
December 5, 2017: Zhongguo Xue Xi Chong Bing Fang Zhi za Zhi, Chinese Journal of Schistosomiasis Control
https://www.readbyqxmd.com/read/29469365/-epidemic-characteristics-of-imported-falciparum-malaria-in-huai-an-city
#9
Jia Cong-Ying, Wang Wei-Ming, Yang Wen-Zhou, Gao Hong-Xia
OBJECTIVE: To understand the situation and epidemic characteristics of imported falciparum malaria in Huai'an City from 2010 to 2016, so as to provide the evidence for formulating the prevention and control strategies of imported falciparum malaria in the city. METHODS: The epidemic data of imported falciparum malaria in Huai'an City from 2010 to 2016 were analyzed by using the descriptive epidemiological method. RESULTS: A total of 308 malaria cases were reported in Huai'an City from 2010 to 2016 with the average annual incidence of 0...
July 28, 2017: Zhongguo Xue Xi Chong Bing Fang Zhi za Zhi, Chinese Journal of Schistosomiasis Control
https://www.readbyqxmd.com/read/29469364/-epidemiological-characteristics-of-malaria-in-leshan-city-1950-2015
#10
Qin Li-Ping, Xu Rong-Fang, Li Zhi-Bin, Luo Yao, Wang Jia, Jiang Dun-Tao, Lei Xiao
OBJECTIVE: To analyze the epidemiological characteristics of malaria in Leshan City, so as to provide the evidence for formulating the strategy and measures for consolidating the achievements of malaria elimination. METHODS: The data of epidemiological characteristics of malaria in Leshan City from 1950 to 2015 were collected and analyzed with the descriptive epidemiology method. RESULTS: There were four larger scale epidemics of malaria in Leshan City from 1950 to 2015...
May 31, 2017: Zhongguo Xue Xi Chong Bing Fang Zhi za Zhi, Chinese Journal of Schistosomiasis Control
https://www.readbyqxmd.com/read/29469323/-molecular-epidemiology-of-cryptosporidium-infection-in-infants-with-diarrhea-in-wuhan-city
#11
Liu Xiao-Jie, Mao Tie-Bo, Wu Peng, Zhou Rui
OBJECTIVE: To understand the prevalence of Cryptosporidium infection in diarrhea infants under 2 years old in Wuhan City, so as to provide the epidemiological evidence for the prevention and treatment of cryptosporidiosis. METHODS: The fecal samples from infants under 2 years old with diarrhea were collected in Hubei General Hospital and Central South Hospital in Wuhan City, Hubei Province from August 2014 to July 2015. The fecal samples were stored in 2.5% potassium dichromate at 4 ℃ after filtered...
March 14, 2017: Zhongguo Xue Xi Chong Bing Fang Zhi za Zhi, Chinese Journal of Schistosomiasis Control
https://www.readbyqxmd.com/read/29468821/urinary-metabolomics-profiles-associated-to-bovine-meat-ingestion-in-humans
#12
Nadezda V Khodorova, Douglas N Rutledge, Marion Oberli, David Mathiron, Paulo Marcelo, Robert Benamouzig, Daniel Tomé, Claire Gaudichon, Serge Pilard
SCOPE: The impact of meat consumption on human health is widely examined in nutritional epidemiological studies, especially due to the connexion between the consumption of red and processed meat and the risk of colon cancer. Food questionnaires do not assess the exposure to different methods of meat cooking. This study aimed to identify biomarkers of the acute ingestion of bovine meat cooked with 2 different processes. METHODS AND RESULTS: Non-targeted UPLC-MS metabolite profiling was done on urine samples obtained from 24 healthy volunteers before and 8h after the ingestion of a single meal composed of intrinsically15 N labelled bovine meat, either cooked at 55 °C for 5 min or at 90 °C for 30 min...
February 22, 2018: Molecular Nutrition & Food Research
https://www.readbyqxmd.com/read/29468556/what-is-the-minimum-number-of-examined-lymph-nodes-after-neoadjuvant-therapy-in-rectal-cancer
#13
Peng Gao, Yongxi Song, Yuchong Yang, Shan Zhao, Yu Sun, Jingxu Sun, Xiaowan Chen, Zhenning Wang
BACKGROUND: To date, no guidelines have standardized the number of examined lymph nodes (eLNs) after neoadjuvant treatment. This study investigated the minimum number of eLNs required for patients with rectal cancer (RC) who received neoadjuvant treatment. MATERIAL AND METHODS: This study was based on data from the Surveillance, Epidemiology, and End Results (SEER)-Medicare-linked database. We included 2173 patients with RC who received neoadjuvant therapy. Restricted cubic spline was used to analyze the association between eLNs and lymph node metastasis (LNM)...
February 21, 2018: Journal of Gastrointestinal Surgery: Official Journal of the Society for Surgery of the Alimentary Tract
https://www.readbyqxmd.com/read/29467814/fast-phylogenetic-inference-from-typing-data
#14
João A Carriço, Maxime Crochemore, Alexandre P Francisco, Solon P Pissis, Bruno Ribeiro-Gonçalves, Cátia Vaz
Background: Microbial typing methods are commonly used to study the relatedness of bacterial strains. Sequence-based typing methods are a gold standard for epidemiological surveillance due to the inherent portability of sequence and allelic profile data, fast analysis times and their capacity to create common nomenclatures for strains or clones. This led to development of several novel methods and several databases being made available for many microbial species. With the mainstream use of High Throughput Sequencing, the amount of data being accumulated in these databases is huge, storing thousands of different profiles...
2018: Algorithms for Molecular Biology: AMB
https://www.readbyqxmd.com/read/29467583/bone-metastasis-pattern-in-initial-metastatic-breast-cancer-a-population-based-study
#15
Zhenchong Xiong, Guangzheng Deng, Xinjian Huang, Xing Li, Xinhua Xie, Jin Wang, Zeyu Shuang, Xi Wang
Purpose: Bone is one of the most common sites of breast cancer metastasis, and population-based studies of patients with bone metastasis in initial metastatic breast cancer (MBC) are lacking. Materials and methods: From 2010 to 2013, 245,707 breast cancer patients and 8901 patients diagnosed with initial bone metastasis were identified by Surveillance, Epidemiology, and End Results database of the National Cancer Institute. Multivariate logistic and Cox regression were used to identify predictive factors for the presence of bone metastasis and prognosis factors...
2018: Cancer Management and Research
https://www.readbyqxmd.com/read/29467055/molecular-serogrouping-of-escherichia-coli
#16
Chitrita DebRoy, Pina M Fratamico, Elisabeth Roberts
O-antigens present on the surface of Escherichia coli provide antigenic specificity for the strain and are the main components for O-serogroup designation. Serotyping using O-group-specific antisera for the identification of E. coli O-serogroups has been traditionally the gold-standard for distinguishing E. coli strains. Knowledge of the O-group is important for determining pathogenic lineage, classifying E. coli for epidemiological studies, for determining virulence, and for tracing outbreaks of diseases and sources of infection...
February 22, 2018: Animal Health Research Reviews
https://www.readbyqxmd.com/read/29465545/metformin-reduces-the-risk-of-cancer-in-patients-with-type-2-diabetes-an-analysis-based-on-the-korean-national-diabetes-program-cohort
#17
Hae Jin Kim, SooJin Lee, Ki Hong Chun, Ja Young Jeon, Seung Jin Han, Dae Jung Kim, Young Seol Kim, Jeong-Taek Woo, Moon-Suk Nam, Sei Hyun Baik, Kyu Jeung Ahn, Kwan Woo Lee
The epidemiological literature suggests that insulin resistance, hyperinsulinemia, and increased levels of insulin-like growth factors place patients with type 2 diabetes mellitus (T2DM) at greater risk of cancer. The association between cancer incidence and the use of antidiabetic medications in patients with T2DM has been recently examined. There have been conflicting reports regarding an association between metformin and cancer risk. The aim of this study was to investigate the relationship between metformin use and the incidence of cancer in Koreans with T2DM...
February 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29464663/incidence-and-survival-of-gliomatosis-cerebri-a-population-based-cancer-registration-study
#18
Marios K Georgakis, Dimitrios Spinos, Apostolos Pourtsidis, Amanda Psyrri, Ioannis G Panourias, Spyridon Sgouros, Eleni Th Petridou
Gliomatosis cerebri (GC) comprises a rare widespread infiltrating growth pattern of diffuse gliomas. We explored the incidence patterns and survival rates of GC in a population-based registration sample from the Surveillance, Epidemiology and End, Results database (1973-2012). GC cases (n = 176) were identified based on their International Classification of Diseases in Oncology (ICD-O-3) morphology code (9381). We calculated age-adjusted incidence rates (AIR) and evaluated temporal trends. Survival was assessed with Kaplan-Meier curves and Cox regression models...
February 20, 2018: Journal of Neuro-oncology
https://www.readbyqxmd.com/read/29464547/comparative-evaluation-of-technetium-99m-diethylenetriaminepentaacetic-acid-renal-dynamic-imaging-versus-the-modification-of-diet-in-renal-disease-equation-and-the-chronic-kidney-disease-epidemiology-collaboration-equation-for-the-estimation-of-gfr
#19
Qi Huang, Yunshuang Chen, Min Zhang, Sihe Wang, Weiguang Zhang, Guangyan Cai, Xiangmei Chen, Xuefeng Sun
PURPOSE: We compared the performance of technetium-99m-diethylenetriaminepentaacetic acid (99m Tc-DTPA) renal dynamic imaging (RDI), the MDRD equation, and the CKD EPI equation to estimate glomerular filtration rate (GFR). METHODS: A total of 551 subjects, including CKD patients and healthy individuals, were enrolled in this study. Dual plasma sample clearance method of99m Tc-DTPA was used as the true value for GFR (tGFR). RDI and the MDRD and CKD EPI equations for estimating GFR were compared and evaluated...
February 20, 2018: International Urology and Nephrology
https://www.readbyqxmd.com/read/29463903/feasibility-of-using-urinary-n7-2-carbamoyl-2-hydroxyethyl-guanine-as-a-biomarker-for-acrylamide-exposed-workers
#20
Yu-Fang Huang, Chih-Chun Jean Huang, Chensheng Alex Lu, Mei-Lien Chen, Saou-Hsing Liou, Su-Yin Chiang, Kuen-Yuh Wu
Acrylamide (AA), a probable human carcinogen, is a widely-used industrial chemical but is also present in tobacco smoke and carbohydrate-rich foods processed at high temperatures. AA is metabolized to glycidamide (GA) to cause the formation of DNA adducts. N7-(2-carbamoyl-2-hydroxyethyl) guanine (N7-GAG), the most abundant DNA adduct induced by GA, was recently detected in urine of smokers and non-smokers. In this study, we assessed the variability of AA exposure and biomarkers of AA exposure in urine samples repeatedly collected from AA-exposed workers and explored the half-life of N7-GAG...
February 20, 2018: Journal of Exposure Science & Environmental Epidemiology
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