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JOURNAL ARTICLE
Alejandra Escós, Ester Diaz-Mora, Michael Pattison, Pilar Fajardo, Diego González-Romero, Ana Risco, José Martín-Gómez, Éric Bonneil, Nahum Sonenberg, Seyed Mehdi Jafarnejad, Juan José Sanz-Ezquerro, Steven C Ley, Ana Cuenda
Evidence implicating p38γ and p38δ (p38γ/p38δ) in inflammation are mainly based on experiments using Mapk12/Mapk13 -deficient (p38γ/δKO) mice, which show low levels of TPL2, the kinase upstream of MKK1-ERK1/2 in myeloid cells. This could obscure p38γ/p38δ roles, since TPL2 is essential for regulating inflammation. Here, we generated a Mapk12 D171A/D171A / Mapk13 -/- (p38γ/δKIKO) mouse, expressing kinase-inactive p38γ and lacking p38δ. This mouse exhibited normal TPL2 levels, making it an excellent tool to elucidate specific p38γ/p38δ functions...
July 17, 2023: ELife
#22
JOURNAL ARTICLE
Shohei Yoshida, Tomoaki Nakata, Masanao Naya, Mitsuru Momose, Yasuyo Taniguchi, Yoshimitsu Fukushima, Masao Moroi, Atsutaka Okizaki, Akiyoshi Hashimoto, Takatoyo Kiko, Satoshi Hida, Kazuya Takehana, Kenichi Nakajima
Background: Definitions of cardiac sarcoidosis (CS) differ among guidelines. Any systemic histological finding of CS is essential for the diagnosis of CS in the 2014 Heart Rhythm Society statement, but not necessary in the Japanese Circulation Society 2016 guidelines. This study aimed to reveal the differences in outcomes by comparing 2 groups, namely CS patients with or without systemic histologically proven granuloma. Methods and Results: This study retrospectively included 231 consecutive patients with CS...
June 9, 2023: Circulation reports
#23
JOURNAL ARTICLE
Enrico Schifani, Antonio Alicata, Lech Borowiec, Fede García, Vincenzo Gentile, Kiko Gómez, Elia Nalini, Fabrizio Rigato, Sämi Schär, Antonio Scupola, Roger Vila, Mattia Menchetti
There are only two Aphaenogaster species from the subterranea group in the western Mediterranean: A.ichnusa Santschi, 1925, from south-western Europe, and A.subterranea (Latreille, 1798), also occurring in central and eastern Europe. Historically, the two species have been widely misunderstood: A.ichnusa was long considered a Sardinian endemic subspecies of A.subterranea , while its continental populations were misidentified as A.subterranea s. str. Recently, A.ichnusa was elevated to species rank and its worker caste was redescribed with that of A...
2023: ZooKeys
#24
JOURNAL ARTICLE
Alberto Baudena, Rainer Kiko, Isabel Jalón-Rojas, Maria Luiza Pedrotti
Plastic is a widespread marine pollutant, with most studies focusing on the distribution of floating plastic debris at the sea surface. Recent evidence, however, indicates a significant presence of such low density plastic in the water column and at the seafloor, but information on its origin and dispersion is lacking. Here, we studied the pathways and fate of sinking plastic debris in the Mediterranean Sea, one of the most polluted world seas. We used a recent Lagrangian plastic-tracking model, forced with realistic parameters, including a maximum estimated sinking speed of 7...
May 1, 2023: Environmental Science & Technology
#25
JOURNAL ARTICLE
Yuya Sakuma, Takeshi Shimizu, Yuta Kurosawa, Himika Ohara, Yuki Muto, Yu Sato, Takatoyo Kiko, Akihiko Sato, Tomofumi Misaka, Akiomi Yoshihisa, Takayoshi Yamaki, Kazuhiko Nakazato, Takafumi Ishida, Yasuchika Takeishi
BACKGROUND: Bleeding is a frequent event in coronary artery disease (CAD) patients treated with antiplatelet therapy after percutaneous coronary intervention (PCI). The impact of bleeding in CAD patients with antiplatelet therapy for cancer diagnosis remains unclear. METHODS AND RESULTS: Consecutive 1565 CAD patients treated with antiplatelet therapy after PCI, without anticoagulation therapy, were enrolled. We aimed to investigate the relationships between bleeding events and the incidence of new cancer diagnosis...
April 20, 2023: Journal of Cardiology
#26
Shuhei Yoshida, Haruki Matsumoto, Jumpei Temmoku, Norshalena Shakespear, Yuichiro Kiko, Kentaro Kikuchi, Yuya Sumichika, Kenji Saito, Yuya Fujita, Naoki Matsuoka, Tomoyuki Asano, Shuzo Sato, Eiji Suzuki, Hiroshi Watanabe, Hiromasa Ohira, Kiyoshi Migita
Temporal arteritis (TA) is a large-vessel vasculitis mostly seen in older patients. Amyloid A (AA) amyloidosis secondary to a chronic inflammation induces multiple organ dysfunctions, including a dysfunction of the gastrointestinal tract. Herein, we present a case of TA complicated by AA amyloidosis that was resistant to oral and intravenous steroids. An 80-year-old man with a history of new-onset headache, jaw claudication, and distended temporal arteries was referred to our department. On admission, the patient presented with tenderness and a subcutaneous temporal nodule in both temple arteries...
2023: Frontiers in Immunology
#27
JOURNAL ARTICLE
B E Aboona, J Adam, L Adamczyk, J R Adams, I Aggarwal, M M Aggarwal, Z Ahammed, D M Anderson, E C Aschenauer, J Atchison, V Bairathi, W Baker, J G Ball Cap, K Barish, R Bellwied, P Bhagat, A Bhasin, S Bhatta, J Bielcik, J Bielcikova, J D Brandenburg, X Z Cai, H Caines, M Calderón de la Barca Sánchez, D Cebra, J Ceska, I Chakaberia, P Chaloupka, B K Chan, Z Chang, D Chen, J Chen, J H Chen, Z Chen, J Cheng, Y Cheng, S Choudhury, W Christie, X Chu, H J Crawford, M Csanád, G Dale-Gau, A Das, M Daugherity, I M Deppner, A Dhamija, L Di Carlo, L Didenko, P Dixit, X Dong, J L Drachenberg, E Duckworth, J C Dunlop, J Engelage, G Eppley, S Esumi, O Evdokimov, A Ewigleben, O Eyser, R Fatemi, S Fazio, C J Feng, Y Feng, E Finch, Y Fisyak, F A Flor, C Fu, C A Gagliardi, T Galatyuk, F Geurts, N Ghimire, A Gibson, K Gopal, X Gou, D Grosnick, A Gupta, W Guryn, A Hamed, Y Han, S Harabasz, M D Harasty, J W Harris, H Harrison, W He, X H He, Y He, S Heppelmann, N Herrmann, L Holub, C Hu, Q Hu, Y Hu, H Huang, H Z Huang, S L Huang, T Huang, X Huang, Y Huang, Y Huang, T J Humanic, D Isenhower, M Isshiki, W W Jacobs, A Jalotra, C Jena, A Jentsch, Y Ji, J Jia, C Jin, X Ju, E G Judd, S Kabana, M L Kabir, S Kagamaster, D Kalinkin, K Kang, D Kapukchyan, K Kauder, H W Ke, D Keane, M Kelsey, Y V Khyzhniak, D P Kikoła, B Kimelman, D Kincses, I Kisel, A Kiselev, A G Knospe, H S Ko, L K Kosarzewski, L Kramarik, L Kumar, S Kumar, R Kunnawalkam Elayavalli, R Lacey, J M Landgraf, J Lauret, A Lebedev, J H Lee, Y H Leung, N Lewis, C Li, C Li, W Li, X Li, Y Li, Y Li, Z Li, X Liang, Y Liang, R Licenik, T Lin, M A Lisa, C Liu, F Liu, H Liu, H Liu, L Liu, T Liu, X Liu, Y Liu, Z Liu, T Ljubicic, W J Llope, O Lomicky, R S Longacre, E Loyd, T Lu, N S Lukow, X F Luo, L Ma, R Ma, Y G Ma, N Magdy, D Mallick, S Margetis, C Markert, H S Matis, J A Mazer, G McNamara, K Mi, S Mioduszewski, B Mohanty, I Mooney, A Mukherjee, M I Nagy, A S Nain, J D Nam, Md Nasim, D Neff, J M Nelson, D B Nemes, M Nie, T Niida, R Nishitani, T Nonaka, A S Nunes, G Odyniec, A Ogawa, S Oh, K Okubo, B S Page, R Pak, J Pan, A Pandav, A K Pandey, T Pani, A Paul, B Pawlik, D Pawlowska, C Perkins, J Pluta, B R Pokhrel, M Posik, T Protzman, V Prozorova, N K Pruthi, M Przybycien, J Putschke, Z Qin, H Qiu, A Quintero, C Racz, S K Radhakrishnan, N Raha, R L Ray, R Reed, H G Ritter, C W Robertson, M Robotkova, J L Romero, M A Rosales Aguilar, D Roy, P Roy Chowdhury, L Ruan, A K Sahoo, N R Sahoo, H Sako, S Salur, S Sato, W B Schmidke, N Schmitz, F-J Seck, J Seger, R Seto, P Seyboth, N Shah, P V Shanmuganathan, M Shao, T Shao, M Sharma, N Sharma, R Sharma, S R Sharma, A I Sheikh, D Y Shen, K Shen, S S Shi, Y Shi, Q Y Shou, F Si, J Singh, S Singha, P Sinha, M J Skoby, N Smirnov, Y Söhngen, Y Song, B Srivastava, T D S Stanislaus, M Stefaniak, D J Stewart, B Stringfellow, Y Su, A A P Suaide, M Sumbera, C Sun, X Sun, Y Sun, Y Sun, B Surrow, Z W Sweger, P Szymanski, A Tamis, A H Tang, Z Tang, T Tarnowsky, J H Thomas, A R Timmins, D Tlusty, T Todoroki, C A Tomkiel, S Trentalange, R E Tribble, P Tribedy, T Truhlar, B A Trzeciak, O D Tsai, C Y Tsang, Z Tu, T Ullrich, D G Underwood, I Upsal, G Van Buren, J Vanek, I Vassiliev, V Verkest, F Videbæk, S A Voloshin, F Wang, G Wang, J S Wang, X Wang, Y Wang, Y Wang, Y Wang, Z Wang, J C Webb, P C Weidenkaff, G D Westfall, D Wielanek, H Wieman, G Wilks, S W Wissink, R Witt, J Wu, J Wu, X Wu, Y Wu, B Xi, Z G Xiao, W Xie, H Xu, N Xu, Q H Xu, Y Xu, Y Xu, Z Xu, Z Xu, G Yan, Z Yan, C Yang, Q Yang, S Yang, Y Yang, Z Ye, Z Ye, L Yi, K Yip, Y Yu, H Zbroszczyk, W Zha, C Zhang, D Zhang, J Zhang, S Zhang, X Zhang, Y Zhang, Y Zhang, Y Zhang, Z J Zhang, Z Zhang, Z Zhang, F Zhao, J Zhao, M Zhao, C Zhou, J Zhou, S Zhou, Y Zhou, X Zhu, M Zurek, M Zyzak
We report on measurements of sequential ϒ suppression in Au+Au collisions at sqrt[s_{NN}]=200 GeV with the STAR detector at the Relativistic Heavy Ion Collider (RHIC) through both the dielectron and dimuon decay channels. In the 0%-60% centrality class, the nuclear modification factors (R_{AA}), which quantify the level of yield suppression in heavy-ion collisions compared to p+p collisions, for ϒ(1S) and ϒ(2S) are 0.40±0.03(stat)±0.03(sys)±0.09(norm) and 0.26±0...
March 17, 2023: Physical Review Letters
#28
JOURNAL ARTICLE
Ali Yasrebi, Daniel Regan, Troy A Roepke
Circulating 17β-estradiol (E2) controls energy homeostasis and feeding behaviors primarily by its nuclear receptor, estrogen receptor (ER)α. As such, it is important to understand the role of ER α signaling in the neuroendocrine control of feeding. Our previous data indicated that the loss of ER α signaling through estrogen response elements (ERE) alters food intake in a female mouse model. Hence, we hypothesize that ERE-dependent ERα is necessary for typical feeding behaviors in mice...
March 27, 2023: Steroids
#29
JOURNAL ARTICLE
Katie Fitzgerald Jones, Matthew J Bair, Sarah Margaret Orris, Mallory Johnson, Jane M Liebschutz, William Demonte, Olivio J Clay, Amy L Durr, Claire E Farel, Deana Agil, Greer Burkholder, Bernadette Johnson, Kendall Conder, Mireille Leone, Sonia Napravnik, Tammi Thomas, Lindsay Browne, Kiko King, LaToya Mullen, Jessica Merlin
BACKGROUND: Behavioral interventions for chronic pain among people with HIV (PWH) are understudied, with great potential to improve pain and function. Chronic pain is an important comorbidity that affects between 30% and 85% of PWH and is associated with greater odds of functional impairment, increased emergency room utilization, suboptimal retention in HIV care, and failure to achieve virologic suppression. However, to date, there are few effective and scalable interventions for chronic pain in PWH...
March 21, 2023: Contemporary Clinical Trials
#30
JOURNAL ARTICLE
Kenji Fukushima, Keiichiro Endo, Ryo Yamakuni, Takatoyo Kiko, Hirofumi Sekino, Katsuyuki Kikori, Naoyuki Ukon, Shiro Ishii, Takayoshi Yamaki, Hiroshi Ito, Yasuchika Takeishi
BACKGROUND: To compare phase analysis with positron emission tomography (PA) and magnetic resonance feature tracking derived myocardial strain (FT) for left ventricular (LV) mechanical dyssynchrony using PETMR system in patients with ischemic heart disease. METHODS AND RESULTS: Patients who underwent rest-pharmacological stress 13 N ammonia PETMR were enrolled. Histogram bandwidth (BW) and phase standard deviation (PSD) were compared to global longitudinal, long axis radial, short axis circumferential, and radial strain (GLS, GRS, SA Circ, and SA Rad) obtained from FT...
March 14, 2023: Journal of Nuclear Cardiology
#31
JOURNAL ARTICLE
Kiko Hasegawa, Nobuyuki Takenaka, Maaya Yamamoto, Yoshiki Sakoda, Atsu Aiba, Takaya Satoh
White adipocytes act as lipid storage, and play an important role in energy homeostasis. The small GTPase Rac1 has been implicated in the regulation of insulin-stimulated glucose uptake in white adipocytes. Adipocyte-specific rac1 -knockout (adipo- rac1 -KO) mice exhibit atrophy of subcutaneous and epididymal white adipose tissue (WAT); white adipocytes in these mice are significantly smaller than controls. Here, we aimed to investigate the mechanisms underlying the aberrations in the development of Rac1-deficient white adipocytes by employing in vitro differentiation systems...
February 27, 2023: International Journal of Molecular Sciences
#32
JOURNAL ARTICLE
B E Aboona, J Adam, L Adamczyk, J R Adams, I Aggarwal, M M Aggarwal, Z Ahammed, D M Anderson, E C Aschenauer, J Atchison, V Bairathi, W Baker, J G Ball Cap, K Barish, R Bellwied, P Bhagat, A Bhasin, S Bhatta, J Bielcik, J Bielcikova, J D Brandenburg, X Z Cai, H Caines, M Calderón de la Barca Sánchez, D Cebra, J Ceska, I Chakaberia, P Chaloupka, B K Chan, Z Chang, D Chen, J Chen, J H Chen, Z Chen, J Cheng, Y Cheng, S Choudhury, W Christie, X Chu, H J Crawford, M Csanád, G Dale-Gau, A Das, M Daugherity, I M Deppner, A Dhamija, L Di Carlo, L Didenko, P Dixit, X Dong, J L Drachenberg, E Duckworth, J C Dunlop, J Engelage, G Eppley, S Esumi, O Evdokimov, A Ewigleben, O Eyser, R Fatemi, S Fazio, C J Feng, Y Feng, E Finch, Y Fisyak, F A Flor, C Fu, C A Gagliardi, T Galatyuk, F Geurts, N Ghimire, A Gibson, K Gopal, X Gou, D Grosnick, A Gupta, W Guryn, A Hamed, Y Han, S Harabasz, M D Harasty, J W Harris, H Harrison, W He, X H He, Y He, S Heppelmann, N Herrmann, L Holub, C Hu, Q Hu, Y Hu, H Huang, H Z Huang, S L Huang, T Huang, X Huang, Y Huang, Y Huang, T J Humanic, D Isenhower, M Isshiki, W W Jacobs, A Jalotra, C Jena, A Jentsch, Y Ji, J Jia, C Jin, X Ju, E G Judd, S Kabana, M L Kabir, S Kagamaster, D Kalinkin, K Kang, D Kapukchyan, K Kauder, H W Ke, D Keane, M Kelsey, Y V Khyzhniak, D P Kikoła, B Kimelman, D Kincses, I Kisel, A Kiselev, A G Knospe, H S Ko, L K Kosarzewski, L Kramarik, L Kumar, S Kumar, R Kunnawalkam Elayavalli, R Lacey, J M Landgraf, J Lauret, A Lebedev, J H Lee, Y H Leung, N Lewis, C Li, C Li, W Li, X Li, Y Li, Y Li, Z Li, X Liang, Y Liang, R Licenik, T Lin, M A Lisa, C Liu, F Liu, H Liu, H Liu, L Liu, T Liu, X Liu, Y Liu, Z Liu, T Ljubicic, W J Llope, O Lomicky, R S Longacre, E Loyd, T Lu, N S Lukow, X F Luo, L Ma, R Ma, Y G Ma, N Magdy, D Mallick, S Margetis, C Markert, H S Matis, J A Mazer, G McNamara, K Mi, S Mioduszewski, B Mohanty, I Mooney, A Mukherjee, M I Nagy, A S Nain, J D Nam, Md Nasim, D Neff, J M Nelson, D B Nemes, M Nie, T Niida, R Nishitani, T Nonaka, A S Nunes, G Odyniec, A Ogawa, S Oh, K Okubo, B S Page, R Pak, J Pan, A Pandav, A K Pandey, T Pani, A Paul, B Pawlik, D Pawlowska, C Perkins, J Pluta, B R Pokhrel, M Posik, T Protzman, V Prozorova, N K Pruthi, M Przybycien, J Putschke, Z Qin, H Qiu, A Quintero, C Racz, S K Radhakrishnan, N Raha, R L Ray, R Reed, H G Ritter, C W Robertson, M Robotkova, J L Romero, M A Rosales Aguilar, D Roy, P Roy Chowdhury, L Ruan, A K Sahoo, N R Sahoo, H Sako, S Salur, S Sato, W B Schmidke, N Schmitz, F-J Seck, J Seger, R Seto, P Seyboth, N Shah, P V Shanmuganathan, M Shao, T Shao, M Sharma, N Sharma, R Sharma, S R Sharma, A I Sheikh, D Y Shen, K Shen, S S Shi, Y Shi, Q Y Shou, F Si, J Singh, S Singha, P Sinha, M J Skoby, N Smirnov, Y Söhngen, Y Song, B Srivastava, T D S Stanislaus, M Stefaniak, D J Stewart, B Stringfellow, Y Su, A A P Suaide, M Sumbera, C Sun, X Sun, Y Sun, Y Sun, B Surrow, Z W Sweger, P Szymanski, A Tamis, A H Tang, Z Tang, T Tarnowsky, J H Thomas, A R Timmins, D Tlusty, T Todoroki, C A Tomkiel, S Trentalange, R E Tribble, P Tribedy, T Truhlar, B A Trzeciak, O D Tsai, C Y Tsang, Z Tu, T Ullrich, D G Underwood, I Upsal, G Van Buren, J Vanek, I Vassiliev, V Verkest, F Videbæk, S A Voloshin, F Wang, G Wang, J S Wang, X Wang, Y Wang, Y Wang, Y Wang, Z Wang, J C Webb, P C Weidenkaff, G D Westfall, D Wielanek, H Wieman, G Wilks, S W Wissink, R Witt, J Wu, J Wu, X Wu, Y Wu, B Xi, Z G Xiao, W Xie, H Xu, N Xu, Q H Xu, Y Xu, Y Xu, Z Xu, Z Xu, G Yan, Z Yan, C Yang, Q Yang, S Yang, Y Yang, Z Ye, Z Ye, L Yi, K Yip, Y Yu, H Zbroszczyk, W Zha, C Zhang, D Zhang, J Zhang, S Zhang, X Zhang, Y Zhang, Y Zhang, Y Zhang, Z J Zhang, Z Zhang, Z Zhang, F Zhao, J Zhao, M Zhao, C Zhou, J Zhou, S Zhou, Y Zhou, X Zhu, M Zurek, M Zyzak
We report the beam energy and collision centrality dependence of fifth and sixth order cumulants (C_{5}, C_{6}) and factorial cumulants (κ_{5}, κ_{6}) of net-proton and proton number distributions, from center-of-mass energy (sqrt[s_{NN}]) 3 GeV to 200 GeV Au+Au collisions at RHIC. Cumulant ratios of net-proton (taken as proxy for net-baryon) distributions generally follow the hierarchy expected from QCD thermodynamics, except for the case of collisions at 3 GeV. The measured values of C_{6}/C_{2} for 0%-40% centrality collisions show progressively negative trend with decreasing energy, while it is positive for the lowest energy studied...
February 24, 2023: Physical Review Letters
#33
Yosuke Suzuki, Kosumo Noda, Nakao Ota, Tomomasa Kondo, Kenichi Haraguchi, Norio Miyoshi, Katsunari Kiko, Kohei Yoshikawa, Shun Ono, Hiroyuki Mizuno, Yasuaki Okada, Takuma Takano, Soichiro Yasuda, Jumpei Oda, Hiroyasu Kamiyama, Sadahisa Tokuda, Rokuya Tanikawa
BACKGROUND: Several treatments for traumatic facial paralysis have been reported, but the role of surgery is still controversial. CASE DESCRIPTION: A 57-year-old man was admitted to our hospital with head trauma due to a fall injury. A total body computed tomography (CT) scan showed a left frontal acute epidural hematoma associated with a left optic canal and petrous bone fractures with the disappearance of the light reflex. Hematoma removal and optic nerve decompression were performed immediately...
2023: Surgical Neurology International
#34
JOURNAL ARTICLE
Tsung-Ming Shih
Recently a novel humanized mouse strain has been successfully generated, in which serum carboxylesterase (CES) knock out (KO) mice (Es1-/-) were further genetically modified by knocking in (KI), or adding, the gene that encodes the human form of acetylcholinesterase (AChE). The resulting human AChE KI and serum CES KO (or KIKO) mouse strain should not only exhibit organophosphorus nerve agent (NA) intoxication in a manner more similar to humans, but also display AChE-specific treatment responses more closely mimicking those of humans to facilitate data translation to pre-clinic trials...
February 25, 2023: Toxicology and Applied Pharmacology
#35
JOURNAL ARTICLE
Kelsey Turley, Kiko Bracker, Catherine Fernan, Emily Gao, Alexandra Orsky, Danni Yang, Virginia Sinnott-Stutzman
OBJECTIVE: To evaluate the use of a modified Sepsis-3 (mSepsis-3) definition compared to the currently used modified Sepsis-2 (mSepsis-2) definition to determine whether the mSepsis-2 or mSepsis-3 stratifications were able to identify populations of dogs ultimately more likely to die from canine parvovirus (CPV) infection. DESIGN: Retrospective, January 2009 to March 2020. SETTING: A private, small animal, urban, referral emergency and specialty hospital...
March 2023: Journal of Veterinary Emergency and Critical Care
#36
REVIEW
Jerome Niquet, Donna Nguyen, Marcio de Araujo Furtado, Lucille Lumley
Despite new antiseizure medications, the development of cholinergic-induced refractory status epilepticus (RSE) continues to be a therapeutic challenge as pharmacoresistance to benzodiazepines and other antiseizure medications quickly develops. Studies conducted by Epilepsia. 2005;46:142 demonstrated that the initiation and maintenance of cholinergic-induced RSE are associated with trafficking and inactivation of gamma-aminobutyric acid A receptors (GABAA R) thought to contribute to the development of benzodiazepine pharmacoresistance...
May 2023: Epilepsia Open
#37
Yosuke Suzuki, Kosumo Noda, Souichirou Yasuda, Yasuaki Okada, Syun Ono, Katsunari Kiko, Kohei Yoshikawa, Norio Miyoshi, Tomomasa Kondo, Kenichi Haraguchi, Jyunpei Oda, Nakao Ota, Hiroyasu Kamiyama, Sadahisa Tokuda, Rokuya Tanikawa
A 59-year-old female with recurrent Anterior Choroidal Artery (AchA) aneurysm was elected for surgery at our institution through a standard pterional approach. Two thin perforating branches were found to origin from the dome of the aneurysm during operation, and therefore complete aneurysm clipping preserving these branches was not feasible. These perforating branches were temporarily occluded under motor-evoked potential (MEP) monitoring. The MEPs remained stable during 10 min of temporary clipping, and we concluded that these branches could be sacrificed, and therefore neck clipping was performed occluding these tiny AchA perforators...
January 2023: Journal of Surgical Case Reports
#38
JOURNAL ARTICLE
Kiko Shibata, Masamichi Kuroda, Etsuro Yamaha, Katsutoshi Arai, Takafumi Fujimoto
There are 2 genetically divergent groups in the dojo loach Misgurnus anguillicaudatus: A and B. Although most wild-type diploids reproduce sexually, clonal diploids (clonal loach) reproduce gynogenetically in certain areas. Clonal loaches produce unreduced isogenic eggs by premeiotic endomitosis, and such diploid eggs develop gynogenetically following activation by the sperm of sympatric wild-type diploids. These clonal loaches have presumably arisen from past hybridization events between 2 different ancestors...
January 20, 2023: Cytogenetic and Genome Research
#39
JOURNAL ARTICLE
Daniel Fil, Robbie L Conley, Aamir R Zuberi, Cathleen M Lutz, Terry Gemelli, Marek Napierala, Jill S Napierala
Friedreich's ataxia (FRDA) is a neurodegenerative disease caused by reduced expression of the mitochondrial protein frataxin (FXN). Most FRDA patients are homozygous for large expansions of GAA repeats in intron 1 of FXN, while some are compound heterozygotes with an expanded GAA tract in one allele and a missense or nonsense mutation in the other. A missense mutation, changing a glycine to valine at position 130 (G130V), is prevalent among the clinical variants. We and others have demonstrated that levels of mature FXN protein in FRDA G130V samples are reduced below those detected in samples harboring homozygous repeat expansions...
February 2023: Neurobiology of Disease
#40
JOURNAL ARTICLE
M S Abdallah, J Adam, L Adamczyk, J R Adams, J K Adkins, G Agakishiev, I Aggarwal, M M Aggarwal, Z Ahammed, I Alekseev, D M Anderson, A Aparin, E C Aschenauer, M U Ashraf, F G Atetalla, A Attri, G S Averichev, V Bairathi, W Baker, J G Ball Cap, K Barish, A Behera, R Bellwied, P Bhagat, A Bhasin, J Bielcik, J Bielcikova, I G Bordyuzhin, J D Brandenburg, A V Brandin, I Bunzarov, J Butterworth, X Z Cai, H Caines, M Calderón de la Barca Sánchez, D Cebra, I Chakaberia, P Chaloupka, B K Chan, F-H Chang, Z Chang, N Chankova-Bunzarova, A Chatterjee, S Chattopadhyay, D Chen, J Chen, J H Chen, X Chen, Z Chen, J Cheng, M Chevalier, S Choudhury, W Christie, X Chu, H J Crawford, M Csanád, M Daugherity, T G Dedovich, I M Deppner, A A Derevschikov, A Dhamija, L Di Carlo, L Didenko, P Dixit, X Dong, J L Drachenberg, E Duckworth, J C Dunlop, N Elsey, J Engelage, G Eppley, S Esumi, O Evdokimov, A Ewigleben, O Eyser, R Fatemi, F M Fawzi, S Fazio, P Federic, J Fedorisin, C J Feng, Y Feng, P Filip, E Finch, Y Fisyak, A Francisco, C Fu, L Fulek, C A Gagliardi, T Galatyuk, F Geurts, N Ghimire, A Gibson, K Gopal, X Gou, D Grosnick, A Gupta, W Guryn, A I Hamad, A Hamed, Y Han, S Harabasz, M D Harasty, J W Harris, H Harrison, S He, W He, X H He, Y He, S Heppelmann, S Heppelmann, N Herrmann, E Hoffman, L Holub, Y Hu, H Huang, H Z Huang, S L Huang, T Huang, X Huang, Y Huang, T J Humanic, G Igo, D Isenhower, W W Jacobs, C Jena, A Jentsch, Y Ji, J Jia, K Jiang, X Ju, E G Judd, S Kabana, M L Kabir, S Kagamaster, D Kalinkin, K Kang, D Kapukchyan, K Kauder, H W Ke, D Keane, A Kechechyan, M Kelsey, Y V Khyzhniak, D P Kikoła, C Kim, B Kimelman, D Kincses, I Kisel, A Kiselev, A G Knospe, L Kochenda, L K Kosarzewski, L Kramarik, P Kravtsov, L Kumar, S Kumar, R Kunnawalkam Elayavalli, J H Kwasizur, R Lacey, S Lan, J M Landgraf, J Lauret, A Lebedev, R Lednicky, J H Lee, Y H Leung, C Li, C Li, W Li, X Li, Y Li, X Liang, Y Liang, R Licenik, T Lin, Y Lin, M A Lisa, F Liu, H Liu, H Liu, P Liu, T Liu, X Liu, Y Liu, Z Liu, T Ljubicic, W J Llope, R S Longacre, E Loyd, N S Lukow, X F Luo, L Ma, R Ma, Y G Ma, N Magdy, D Mallick, S Margetis, C Markert, H S Matis, J A Mazer, N G Minaev, S Mioduszewski, B Mohanty, M M Mondal, I Mooney, D A Morozov, A Mukherjee, M Nagy, J D Nam, Md Nasim, K Nayak, D Neff, J M Nelson, D B Nemes, M Nie, G Nigmatkulov, T Niida, R Nishitani, L V Nogach, T Nonaka, A S Nunes, G Odyniec, A Ogawa, S Oh, V A Okorokov, B S Page, R Pak, A Pandav, A K Pandey, Y Panebratsev, P Parfenov, B Pawlik, D Pawlowska, H Pei, C Perkins, L Pinsky, R L Pintér, J Pluta, B R Pokhrel, G Ponimatkin, J Porter, M Posik, V Prozorova, N K Pruthi, M Przybycien, J Putschke, H Qiu, A Quintero, C Racz, S K Radhakrishnan, N Raha, R L Ray, R Reed, H G Ritter, M Robotkova, O V Rogachevskiy, J L Romero, D Roy, L Ruan, J Rusnak, N R Sahoo, H Sako, S Salur, J Sandweiss, S Sato, W B Schmidke, N Schmitz, B R Schweid, F Seck, J Seger, M Sergeeva, R Seto, P Seyboth, N Shah, E Shahaliev, P V Shanmuganathan, M Shao, T Shao, A I Sheikh, D Shen, S S Shi, Y Shi, Q Y Shou, E P Sichtermann, R Sikora, M Simko, J Singh, S Singha, M J Skoby, N Smirnov, Y Söhngen, W Solyst, P Sorensen, H M Spinka, B Srivastava, T D S Stanislaus, M Stefaniak, D J Stewart, M Strikhanov, B Stringfellow, A A P Suaide, M Sumbera, B Summa, X M Sun, X Sun, Y Sun, Y Sun, B Surrow, D N Svirida, Z W Sweger, P Szymanski, A H Tang, Z Tang, A Taranenko, T Tarnowsky, J H Thomas, A R Timmins, D Tlusty, T Todoroki, M Tokarev, C A Tomkiel, S Trentalange, R E Tribble, P Tribedy, S K Tripathy, T Truhlar, B A Trzeciak, O D Tsai, Z Tu, T Ullrich, D G Underwood, I Upsal, G Van Buren, J Vanek, A N Vasiliev, I Vassiliev, V Verkest, F Videbæk, S Vokal, S A Voloshin, G Wang, J S Wang, P Wang, Y Wang, Y Wang, Z Wang, J C Webb, P C Weidenkaff, L Wen, G D Westfall, H Wieman, S W Wissink, J Wu, Y Wu, B Xi, Z G Xiao, G Xie, W Xie, H Xu, N Xu, Q H Xu, Y Xu, Z Xu, Z Xu, C Yang, Q Yang, S Yang, Y Yang, Z Ye, Z Ye, L Yi, K Yip, Y Yu, H Zbroszczyk, W Zha, C Zhang, D Zhang, J Zhang, S Zhang, S Zhang, X P Zhang, Y Zhang, Y Zhang, Y Zhang, Z J Zhang, Z Zhang, Z Zhang, J Zhao, C Zhou, X Zhu, Z Zhu, M Zurek, M Zyzak
Elliptic flow measurements from two-, four-, and six-particle correlations are used to investigate flow fluctuations in collisions of U+U at sqrt[s_{NN}]=193 GeV, Cu+Au at sqrt[s_{NN}]=200 GeV and Au+Au spanning the range sqrt[s_{NN}]=11.5-200 GeV. The measurements show a strong dependence of the flow fluctuations on collision centrality, a modest dependence on system size, and very little if any, dependence on particle species and beam energy. The results, when compared to similar LHC measurements, viscous hydrodynamic calculations, and trento model eccentricities, indicate that initial-state-driven fluctuations predominate the flow fluctuations generated in the collisions studied...
December 16, 2022: Physical Review Letters
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