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https://www.readbyqxmd.com/read/28220039/hormone-signaling-and-fatty-liver-in-females-analysis-of-estrogen-receptor-%C3%AE-mutant-mice
#1
S Hart-Unger, Y Arao, K J Hamilton, S L Lierz, D E Malarkey, S C Hewitt, M Freemark, K S Korach
BACKGROUND: Treatment with estrogen in early menopausal women protects against development of hepatic steatosis and nonalcoholic fatty liver disease but estrogen has undesirable side effects, which negate its beneficial effects in premenopausal and postmenopausal women. Targeted therapies require better understanding of the target sites and mechanisms by which estrogen signaling exerts its protective effects in women. Estrogen receptor α (ERα) is thought to be the primary mediator for estrogen signaling to protect against hepatic steatosis...
March 21, 2017: International Journal of Obesity: Journal of the International Association for the Study of Obesity
https://www.readbyqxmd.com/read/28106415/charge-dependent-directed-flow-in-cu-au-collisions-at-sqrt-s_-nn-200%C3%A2-%C3%A2-gev
#2
L Adamczyk, J K Adkins, G Agakishiev, M M Aggarwal, Z Ahammed, I Alekseev, D M Anderson, R Aoyama, A Aparin, D Arkhipkin, E C Aschenauer, M U Ashraf, A Attri, G S Averichev, X Bai, V Bairathi, R Bellwied, A Bhasin, A K Bhati, P Bhattarai, J Bielcik, J Bielcikova, L C Bland, I G Bordyuzhin, J Bouchet, J D Brandenburg, A V Brandin, I Bunzarov, J Butterworth, H Caines, M Calderón de la Barca Sánchez, J M Campbell, D Cebra, I Chakaberia, P Chaloupka, Z Chang, A Chatterjee, S Chattopadhyay, X Chen, J H Chen, J Cheng, M Cherney, W Christie, G Contin, H J Crawford, S Das, L C De Silva, R R Debbe, T G Dedovich, J Deng, A A Derevschikov, B di Ruzza, L Didenko, C Dilks, X Dong, J L Drachenberg, J E Draper, C M Du, L E Dunkelberger, J C Dunlop, L G Efimov, J Engelage, G Eppley, R Esha, S Esumi, O Evdokimov, O Eyser, R Fatemi, S Fazio, P Federic, J Fedorisin, Z Feng, P Filip, E Finch, Y Fisyak, C E Flores, L Fulek, C A Gagliardi, D Garand, F Geurts, A Gibson, M Girard, L Greiner, D Grosnick, D S Gunarathne, Y Guo, S Gupta, A Gupta, W Guryn, A I Hamad, A Hamed, R Haque, J W Harris, L He, S Heppelmann, S Heppelmann, A Hirsch, G W Hoffmann, S Horvat, B Huang, X Huang, H Z Huang, T Huang, P Huck, T J Humanic, G Igo, W W Jacobs, A Jentsch, J Jia, K Jiang, S Jowzaee, E G Judd, S Kabana, D Kalinkin, K Kang, K Kauder, H W Ke, D Keane, A Kechechyan, Z H Khan, D P Kikoła, I Kisel, A Kisiel, L Kochenda, D D Koetke, L K Kosarzewski, A F Kraishan, P Kravtsov, K Krueger, L Kumar, M A C Lamont, J M Landgraf, K D Landry, J Lauret, A Lebedev, R Lednicky, J H Lee, Y Li, C Li, W Li, X Li, X Li, T Lin, M A Lisa, Y Liu, F Liu, T Ljubicic, W J Llope, M Lomnitz, R S Longacre, X Luo, S Luo, G L Ma, R Ma, Y G Ma, L Ma, N Magdy, R Majka, A Manion, S Margetis, C Markert, H S Matis, D McDonald, S McKinzie, K Meehan, J C Mei, Z W Miller, N G Minaev, S Mioduszewski, D Mishra, B Mohanty, M M Mondal, D A Morozov, M K Mustafa, B K Nandi, Md Nasim, T K Nayak, G Nigmatkulov, T Niida, L V Nogach, T Nonaka, J Novak, S B Nurushev, G Odyniec, A Ogawa, K Oh, V A Okorokov, D Olvitt, B S Page, R Pak, Y X Pan, Y Pandit, Y Panebratsev, B Pawlik, H Pei, C Perkins, P Pile, J Pluta, K Poniatowska, J Porter, M Posik, A M Poskanzer, N K Pruthi, M Przybycien, J Putschke, H Qiu, A Quintero, S Ramachandran, R L Ray, R Reed, M J Rehbein, H G Ritter, J B Roberts, O V Rogachevskiy, J L Romero, J D Roth, L Ruan, J Rusnak, O Rusnakova, N R Sahoo, P K Sahu, I Sakrejda, S Salur, J Sandweiss, A Sarkar, J Schambach, R P Scharenberg, A M Schmah, W B Schmidke, N Schmitz, J Seger, P Seyboth, N Shah, E Shahaliev, P V Shanmuganathan, M Shao, A Sharma, M K Sharma, B Sharma, W Q Shen, S S Shi, Z Shi, Q Y Shou, E P Sichtermann, R Sikora, M Simko, S Singha, M J Skoby, D Smirnov, N Smirnov, W Solyst, L Song, P Sorensen, H M Spinka, B Srivastava, T D S Stanislaus, M Stepanov, R Stock, M Strikhanov, B Stringfellow, T Sugiura, M Sumbera, B Summa, Z Sun, Y Sun, X M Sun, B Surrow, D N Svirida, A H Tang, Z Tang, T Tarnowsky, A Tawfik, J Thäder, J H Thomas, A R Timmins, D Tlusty, T Todoroki, M Tokarev, S Trentalange, R E Tribble, P Tribedy, S K Tripathy, O D Tsai, T Ullrich, D G Underwood, I Upsal, G Van Buren, G van Nieuwenhuizen, R Varma, A N Vasiliev, R Vertesi, F Videbæk, S Vokal, S A Voloshin, A Vossen, G Wang, F Wang, J S Wang, Y Wang, H Wang, Y Wang, J C Webb, G Webb, L Wen, G D Westfall, H Wieman, S W Wissink, R Witt, Y Wu, Z G Xiao, W Xie, G Xie, K Xin, Q H Xu, Y F Xu, H Xu, Z Xu, N Xu, J Xu, C Yang, Y Yang, S Yang, Y Yang, Q Yang, Y Yang, Z Ye, Z Ye, L Yi, K Yip, I-K Yoo, N Yu, H Zbroszczyk, W Zha, J Zhang, X P Zhang, S Zhang, Y Zhang, J B Zhang, Z Zhang, S Zhang, J Zhang, J Zhao, C Zhong, L Zhou, X Zhu, Y Zoulkarneeva, M Zyzak
We present the first measurement of charge-dependent directed flow in Cu+Au collisions at sqrt[s_{NN}]=200  GeV. The results are presented as a function of the particle transverse momentum and pseudorapidity for different centralities. A finite difference between the directed flow of positive and negative charged particles is observed that qualitatively agrees with the expectations from the effects of the initial strong electric field between two colliding ions with different nuclear charges. The measured difference in directed flow is much smaller than that obtained from the parton-hadron-string-dynamics model, which suggests that most of the electric charges, i...
January 6, 2017: Physical Review Letters
https://www.readbyqxmd.com/read/28077814/life-threatening-ventricular-arrhythmia-and-brugada-type-st-segment-elevation-associated-with-acute-ischemia-of-the-right-ventricular-outflow-tract
#3
Rena Nakamura, Mitsuhiro Nishizaki, Kiko Lee, Masato Shimizu, Hiroyuki Fujii, Noriyoshi Yamawake, Harumizu Sakurada, Masayasu Hiraoka, Mitsuaki Isobe
BACKGROUND: Brugada-type ECG (Br-ECG) is occasionally observed during acute myocardial ischemia of the right ventricular outflow tract (RVOT). No studies have explored, however, the association of ventricular tachyarrhythmia and development of Br-ECG due to acute ischemia of the RVOT.Methods and Results:The study included 13 consecutive patients with acute ischemia of the RVOT during coronary catheterization. Patients were divided into 2 groups: those with Br-ECG (group B) and those without (group N)...
February 24, 2017: Circulation Journal: Official Journal of the Japanese Circulation Society
https://www.readbyqxmd.com/read/27992655/use-of-20-intravenous-lipid-emulsion-for-the-treatment-of-loperamide-toxicosis-in-a-collie-homozygous-for-the-abcb1-1%C3%A2-mutation
#4
Whitney M Long, Virginia B Sinnott, Kiko Bracker, Danielle Thomas
OBJECTIVE: To describe the successful treatment of loperamide toxicosis in a dog using intravenous lipid emulsion (ILE). CASE SUMMARY: An 8-month-old male neutered Rough Collie weighing 20.0 kg was given a total dose of 0.75 mg/kg loperamide over 3 days as treatment for diarrhea. The dog was subsequently evaluated for signs of dull mentation, anxiety, ptyalism and ataxia, thought to be a result of loperamide intoxication. The dog was treated with a 1.5 mL/kg IV bolus of 20% ILE solution followed by 0...
December 19, 2016: Journal of Veterinary Emergency and Critical Care
https://www.readbyqxmd.com/read/27901601/activation-of-estrogen-response-element-independent-er%C3%AE-signaling-protects-female-mice-from-diet-induced-obesity
#5
Ali Yasrebi, Janelle A Rivera, Elizabeth A Krumm, Jennifer A Yang, Troy A Roepke
17β-estradiol (E2) regulates central and peripheral mechanisms that control energy and glucose homeostasis predominantly through estrogen receptor α (ERα) acting via receptor binding to estrogen response elements (EREs). ERα signaling is also involved in mediating the effects of E2 on diet-induced obesity (DIO), although the roles of ERE-dependent and -independent ERα signaling in reducing the effects of DIO remain largely unknown. We hypothesize that ERE-dependent ERα signaling is necessary to ameliorate the effects of DIO...
February 1, 2017: Endocrinology
https://www.readbyqxmd.com/read/27589337/impact-of-sulfatase-2-on-cancer-progression-and-prognosis-in-patients-with-renal-cell-carcinoma
#6
Shin Kumagai, Kei Ishibashi, Masao Kataoka, Toshiki Oguro, Yuichirou Kiko, Tomohiko Yanagida, Ken Aikawa, Yoshiyuki Kojima
Heparan sulfate-specific endosulfatase-2 (SULF-2) can modulate the signaling of heparan sulfate proteoglycan-binding proteins. The involvement of SULF-2 in cancer growth varies by cancer type. The roles of SULF-2 expression in the progression and prognosis of renal cell carcinomas (RCC) have not yet been fully clarified. In the present study, the expression levels of SULF-2 mRNA and protein in 49 clinical RCC samples were determined by RT-PCR and immunostaining. The existence of RCC with higher SULF-2 expression and lower SULF-2 expression compared to the adjacent normal kidney tissues was suggested...
November 2016: Cancer Science
https://www.readbyqxmd.com/read/27575947/neurobehavioral-deficits-in-the-kiko-mouse-model-of-friedreich-s-ataxia
#7
Marissa Z McMackin, Chelsea K Henderson, Gino A Cortopassi
Friedreich's Ataxia (FA) is a pediatric neurodegenerative disease whose clinical presentation includes ataxia, muscle weakness, and peripheral sensory neuropathy. The KIKO mouse is an animal model of FA with frataxin deficiency first described in 2002, but neurobehavioral deficits have never been described in this model. The identification of robust neurobehavioral deficits in KIKO mice could support the testing of drugs for FA, which currently has no approved therapy. We tested 13 neurobehavioral tasks to identify a robust KIKO phenotype: Open Field, Grip Strength Test(s), Cylinder, Skilled Forelimb Grasp Task(s), Treadmill Endurance, Locotronic Motor Coordination, Inverted Screen, Treadscan, and Von Frey...
January 1, 2017: Behavioural Brain Research
https://www.readbyqxmd.com/read/27160240/familial-hypertrophic-obstructive-cardiomyopathy-with-the-gla-e66q-mutation-and-zebra-body
#8
Masayoshi Oikawa, Nobuo Sakamoto, Atsushi Kobayashi, Satoshi Suzuki, Akiomi Yoshihisa, Takayoshi Yamaki, Kazuhiko Nakazato, Hitoshi Suzuki, Shu-Ichi Saitoh, Yuichirou Kiko, Hajime Nakano, Takeharu Hayashi, Akinori Kimura, Yasuchika Takeishi
BACKGROUND: Fabry disease is caused by mutations in the α-galactosidase A (GLA) gene, which is located in X-chromosome coding for the lysosomal enzyme of GLA. Among many gene mutations, E66Q mutation is under discussion for its pathogenicity because there is no clinical report showing pathological evidence of Fabry disease with E66Q mutation. CASE PRESENTATION: A 65-year-old Japanese female was referred to our hospital for chest discomfort on effort. Transthoracic echocardiography showed severe left ventricular (LV) hypertrophy with LV outflow obstruction...
May 10, 2016: BMC Cardiovascular Disorders
https://www.readbyqxmd.com/read/27096373/in-situ-imaging-reveals-the-biomass-of-giant-protists-in-the-global-ocean
#9
Tristan Biard, Lars Stemmann, Marc Picheral, Nicolas Mayot, Pieter Vandromme, Helena Hauss, Gabriel Gorsky, Lionel Guidi, Rainer Kiko, Fabrice Not
Planktonic organisms play crucial roles in oceanic food webs and global biogeochemical cycles. Most of our knowledge about the ecological impact of large zooplankton stems from research on abundant and robust crustaceans, and in particular copepods. A number of the other organisms that comprise planktonic communities are fragile, and therefore hard to sample and quantify, meaning that their abundances and effects on oceanic ecosystems are poorly understood. Here, using data from a worldwide in situ imaging survey of plankton larger than 600 μm, we show that a substantial part of the biomass of this size fraction consists of giant protists belonging to the Rhizaria, a super-group of mostly fragile unicellular marine organisms that includes the taxa Phaeodaria and Radiolaria (for example, orders Collodaria and Acantharia)...
April 28, 2016: Nature
https://www.readbyqxmd.com/read/27081970/measurement-of-the-transverse-single-spin-asymmetry-in-p-%C3%A2-p%C3%A2-w-%C3%A2-z-0-at-rhic
#10
L Adamczyk, J K Adkins, G Agakishiev, M M Aggarwal, Z Ahammed, I Alekseev, A Aparin, D Arkhipkin, E C Aschenauer, A Attri, G S Averichev, X Bai, V Bairathi, A Banerjee, R Bellwied, A Bhasin, A K Bhati, P Bhattarai, J Bielcik, J Bielcikova, L C Bland, I G Bordyuzhin, J Bouchet, J D Brandenburg, A V Brandin, I Bunzarov, J Butterworth, H Caines, M Calderón de la Barca Sánchez, J M Campbell, D Cebra, I Chakaberia, P Chaloupka, Z Chang, S Chattopadhyay, X Chen, J H Chen, J Cheng, M Cherney, W Christie, G Contin, H J Crawford, S Das, L C De Silva, R R Debbe, T G Dedovich, J Deng, A A Derevschikov, B di Ruzza, L Didenko, C Dilks, X Dong, J L Drachenberg, J E Draper, C M Du, L E Dunkelberger, J C Dunlop, L G Efimov, J Engelage, G Eppley, R Esha, O Evdokimov, O Eyser, R Fatemi, S Fazio, P Federic, J Fedorisin, Z Feng, P Filip, Y Fisyak, C E Flores, L Fulek, C A Gagliardi, D Garand, F Geurts, A Gibson, M Girard, L Greiner, D Grosnick, D S Gunarathne, Y Guo, A Gupta, S Gupta, W Guryn, A Hamad, A Hamed, R Haque, J W Harris, L He, S Heppelmann, S Heppelmann, A Hirsch, G W Hoffmann, D J Hofman, S Horvat, X Huang, H Z Huang, B Huang, T Huang, P Huck, T J Humanic, G Igo, W W Jacobs, H Jang, A Jentsch, J Jia, K Jiang, E G Judd, S Kabana, D Kalinkin, K Kang, K Kauder, H W Ke, D Keane, A Kechechyan, Z H Khan, D P Kikoła, I Kisel, A Kisiel, L Kochenda, D D Koetke, L K Kosarzewski, A F Kraishan, P Kravtsov, K Krueger, L Kumar, M A C Lamont, J M Landgraf, K D Landry, J Lauret, A Lebedev, R Lednicky, J H Lee, C Li, Y Li, W Li, X Li, X Li, T Lin, M A Lisa, F Liu, T Ljubicic, W J Llope, M Lomnitz, R S Longacre, X Luo, R Ma, L Ma, G L Ma, Y G Ma, N Magdy, R Majka, A Manion, S Margetis, C Markert, D McDonald, K Meehan, J C Mei, N G Minaev, S Mioduszewski, D Mishra, B Mohanty, M M Mondal, D A Morozov, M K Mustafa, B K Nandi, Md Nasim, T K Nayak, G Nigmatkulov, T Niida, L V Nogach, S Y Noh, J Novak, S B Nurushev, G Odyniec, A Ogawa, K Oh, V A Okorokov, D Olvitt, B S Page, R Pak, Y X Pan, Y Pandit, Y Panebratsev, B Pawlik, H Pei, C Perkins, P Pile, J Pluta, K Poniatowska, J Porter, M Posik, A M Poskanzer, N K Pruthi, J Putschke, H Qiu, A Quintero, S Ramachandran, R Raniwala, S Raniwala, R L Ray, H G Ritter, J B Roberts, O V Rogachevskiy, J L Romero, A Roy, L Ruan, J Rusnak, O Rusnakova, N R Sahoo, P K Sahu, I Sakrejda, S Salur, J Sandweiss, A Sarkar, J Schambach, R P Scharenberg, A M Schmah, W B Schmidke, N Schmitz, J Seger, P Seyboth, N Shah, E Shahaliev, P V Shanmuganathan, M Shao, M K Sharma, B Sharma, W Q Shen, Z Shi, S S Shi, Q Y Shou, E P Sichtermann, R Sikora, M Simko, S Singha, M J Skoby, D Smirnov, N Smirnov, W Solyst, L Song, P Sorensen, H M Spinka, B Srivastava, T D S Stanislaus, M Stepanov, R Stock, M Strikhanov, B Stringfellow, M Sumbera, B Summa, Y Sun, Z Sun, X M Sun, B Surrow, D N Svirida, A H Tang, Z Tang, T Tarnowsky, A Tawfik, J Thäder, J H Thomas, A R Timmins, D Tlusty, T Todoroki, M Tokarev, S Trentalange, R E Tribble, P Tribedy, S K Tripathy, O D Tsai, T Ullrich, D G Underwood, I Upsal, G Van Buren, G van Nieuwenhuizen, M Vandenbroucke, R Varma, A N Vasiliev, R Vertesi, F Videbæk, S Vokal, S A Voloshin, A Vossen, J S Wang, Y Wang, F Wang, Y Wang, H Wang, G Wang, J C Webb, G Webb, L Wen, G D Westfall, H Wieman, S W Wissink, R Witt, Y Wu, Z G Xiao, X Xie, W Xie, K Xin, N Xu, Y F Xu, Z Xu, Q H Xu, J Xu, H Xu, Q Yang, Y Yang, S Yang, Y Yang, C Yang, Y Yang, Z Ye, Z Ye, P Yepes, L Yi, K Yip, I-K Yoo, N Yu, H Zbroszczyk, W Zha, S Zhang, Z Zhang, S Zhang, J B Zhang, Y Zhang, J Zhang, J Zhang, X P Zhang, J Zhao, C Zhong, L Zhou, X Zhu, Y Zoulkarneeva, M Zyzak
We present the measurement of the transverse single-spin asymmetry of weak boson production in transversely polarized proton-proton collisions at sqrt[s]=500  GeV by the STAR experiment at RHIC. The measured observable is sensitive to the Sivers function, one of the transverse-momentum-dependent parton distribution functions, which is predicted to have the opposite sign in proton-proton collisions from that observed in deep inelastic lepton-proton scattering. These data provide the first experimental investigation of the nonuniversality of the Sivers function, fundamental to our understanding of QCD...
April 1, 2016: Physical Review Letters
https://www.readbyqxmd.com/read/27035295/beam-energy-dependence-of-the-third-harmonic-of-azimuthal-correlations-in-au-au-collisions-at-rhic
#11
L Adamczyk, J K Adkins, G Agakishiev, M M Aggarwal, Z Ahammed, I Alekseev, A Aparin, D Arkhipkin, E C Aschenauer, A Attri, G S Averichev, X Bai, V Bairathi, R Bellwied, A Bhasin, A K Bhati, P Bhattarai, J Bielcik, J Bielcikova, L C Bland, I G Bordyuzhin, J Bouchet, J D Brandenburg, A V Brandin, I Bunzarov, J Butterworth, H Caines, M Calderón de la Barca Sánchez, J M Campbell, D Cebra, I Chakaberia, P Chaloupka, Z Chang, A Chatterjee, S Chattopadhyay, J H Chen, X Chen, J Cheng, M Cherney, W Christie, G Contin, H J Crawford, S Das, L C De Silva, R R Debbe, T G Dedovich, J Deng, A A Derevschikov, B di Ruzza, L Didenko, C Dilks, X Dong, J L Drachenberg, J E Draper, C M Du, L E Dunkelberger, J C Dunlop, L G Efimov, J Engelage, G Eppley, R Esha, O Evdokimov, O Eyser, R Fatemi, S Fazio, P Federic, J Fedorisin, Z Feng, P Filip, Y Fisyak, C E Flores, L Fulek, C A Gagliardi, D Garand, F Geurts, A Gibson, M Girard, L Greiner, D Grosnick, D S Gunarathne, Y Guo, S Gupta, A Gupta, W Guryn, A I Hamad, A Hamed, R Haque, J W Harris, L He, S Heppelmann, S Heppelmann, A Hirsch, G W Hoffmann, S Horvat, T Huang, X Huang, B Huang, H Z Huang, P Huck, T J Humanic, G Igo, W W Jacobs, H Jang, A Jentsch, J Jia, K Jiang, E G Judd, S Kabana, D Kalinkin, K Kang, K Kauder, H W Ke, D Keane, A Kechechyan, Z H Khan, D P Kikoła, I Kisel, A Kisiel, L Kochenda, D D Koetke, L K Kosarzewski, A F Kraishan, P Kravtsov, K Krueger, L Kumar, M A C Lamont, J M Landgraf, K D Landry, J Lauret, A Lebedev, R Lednicky, J H Lee, X Li, C Li, X Li, Y Li, W Li, T Lin, M A Lisa, F Liu, T Ljubicic, W J Llope, M Lomnitz, R S Longacre, X Luo, R Ma, G L Ma, Y G Ma, L Ma, N Magdy, R Majka, A Manion, S Margetis, C Markert, H S Matis, D McDonald, S McKinzie, K Meehan, J C Mei, N G Minaev, S Mioduszewski, D Mishra, B Mohanty, M M Mondal, D A Morozov, M K Mustafa, B K Nandi, Md Nasim, T K Nayak, G Nigmatkulov, T Niida, L V Nogach, S Y Noh, J Novak, S B Nurushev, G Odyniec, A Ogawa, K Oh, V A Okorokov, D Olvitt, B S Page, R Pak, Y X Pan, Y Pandit, Y Panebratsev, B Pawlik, H Pei, C Perkins, P Pile, J Pluta, K Poniatowska, J Porter, M Posik, A M Poskanzer, N K Pruthi, J Putschke, H Qiu, A Quintero, S Ramachandran, S Raniwala, R Raniwala, R L Ray, H G Ritter, J B Roberts, O V Rogachevskiy, J L Romero, L Ruan, J Rusnak, O Rusnakova, N R Sahoo, P K Sahu, I Sakrejda, S Salur, J Sandweiss, A Sarkar, J Schambach, R P Scharenberg, A M Schmah, W B Schmidke, N Schmitz, J Seger, P Seyboth, N Shah, E Shahaliev, P V Shanmuganathan, M Shao, A Sharma, B Sharma, M K Sharma, W Q Shen, Z Shi, S S Shi, Q Y Shou, E P Sichtermann, R Sikora, M Simko, S Singha, M J Skoby, N Smirnov, D Smirnov, W Solyst, L Song, P Sorensen, H M Spinka, B Srivastava, T D S Stanislaus, M Stepanov, R Stock, M Strikhanov, B Stringfellow, M Sumbera, B Summa, Z Sun, X M Sun, Y Sun, B Surrow, D N Svirida, Z Tang, A H Tang, T Tarnowsky, A Tawfik, J Thäder, J H Thomas, A R Timmins, D Tlusty, T Todoroki, M Tokarev, S Trentalange, R E Tribble, P Tribedy, S K Tripathy, O D Tsai, T Ullrich, D G Underwood, I Upsal, G Van Buren, G van Nieuwenhuizen, M Vandenbroucke, R Varma, A N Vasiliev, R Vertesi, F Videbæk, S Vokal, S A Voloshin, A Vossen, F Wang, G Wang, J S Wang, H Wang, Y Wang, Y Wang, G Webb, J C Webb, L Wen, G D Westfall, H Wieman, S W Wissink, R Witt, Y Wu, Z G Xiao, W Xie, G Xie, K Xin, Y F Xu, Q H Xu, N Xu, H Xu, Z Xu, J Xu, S Yang, Y Yang, Y Yang, C Yang, Y Yang, Q Yang, Z Ye, Z Ye, P Yepes, L Yi, K Yip, I-K Yoo, N Yu, H Zbroszczyk, W Zha, X P Zhang, Y Zhang, J Zhang, J Zhang, S Zhang, S Zhang, Z Zhang, J B Zhang, J Zhao, C Zhong, L Zhou, X Zhu, Y Zoulkarneeva, M Zyzak
We present results from a harmonic decomposition of two-particle azimuthal correlations measured with the STAR detector in Au+Au collisions for energies ranging from sqrt[s_{NN}]=7.7 to 200 GeV. The third harmonic v_{3}^{2}{2}=⟨cos3(ϕ_{1}-ϕ_{2})⟩, where ϕ_{1}-ϕ_{2} is the angular difference in azimuth, is studied as a function of the pseudorapidity difference between particle pairs Δη=η_{1}-η_{2}. Nonzero v_{3}^{2}{2} is directly related to the previously observed large-Δη narrow-Δϕ ridge correlations and has been shown in models to be sensitive to the existence of a low viscosity quark gluon plasma phase...
March 18, 2016: Physical Review Letters
https://www.readbyqxmd.com/read/27008326/retrospective-study-of-122-dogs-that-were-treated-with-the-antifibrinolytic-drug-aminocaproic-acid-2010-2012
#12
Megan Davis, Kiko Bracker
Antifibrinolytic drugs are used to promote hemostasis and decrease the need for red blood cell transfusion. Medical records of 122 dogs that were prescribed either oral or intravenous aminocaproic acid between 2010 and 2012 were evaluated retrospectively. Of the 122 dogs, three experienced possible drug-related adverse effects. No significant differences were identified between dogs that experienced adverse effects and those that did not and the possible adverse effects noted were all minor. All dogs that received packed red blood cell transfusions were evaluated for correlations between baseline packed cell volume or dose of red blood cells and aminocaproic acid dose and no correlation was identified...
May 2016: Journal of the American Animal Hospital Association
https://www.readbyqxmd.com/read/26918982/centrality-and-transverse-momentum-dependence-of-elliptic-flow-of-multistrange-hadrons-and-%C3%AF-meson-in-au-au-collisions-at-%C3%A2-snn-200%C3%A2-%C3%A2-gev
#13
L Adamczyk, J K Adkins, G Agakishiev, M M Aggarwal, Z Ahammed, I Alekseev, A Aparin, D Arkhipkin, E C Aschenauer, G S Averichev, V Bairathi, A Banerjee, R Bellwied, A Bhasin, A K Bhati, P Bhattarai, J Bielcik, J Bielcikova, L C Bland, I G Bordyuzhin, J Bouchet, A V Brandin, I Bunzarov, J Butterworth, H Caines, M Calderón de la Barca Sánchez, J M Campbell, D Cebra, M C Cervantes, I Chakaberia, P Chaloupka, Z Chang, S Chattopadhyay, J H Chen, X Chen, J Cheng, M Cherney, W Christie, G Contin, H J Crawford, S Das, L C De Silva, R R Debbe, T G Dedovich, J Deng, A A Derevschikov, B di Ruzza, L Didenko, C Dilks, X Dong, J L Drachenberg, J E Draper, C M Du, L E Dunkelberger, J C Dunlop, L G Efimov, J Engelage, G Eppley, R Esha, O Evdokimov, O Eyser, R Fatemi, S Fazio, P Federic, J Fedorisin, Z Feng, P Filip, Y Fisyak, C E Flores, L Fulek, C A Gagliardi, D Garand, F Geurts, A Gibson, M Girard, L Greiner, D Grosnick, D S Gunarathne, Y Guo, S Gupta, A Gupta, W Guryn, A Hamad, A Hamed, R Haque, J W Harris, L He, S Heppelmann, S Heppelmann, A Hirsch, G W Hoffmann, D J Hofman, S Horvat, X Huang, B Huang, H Z Huang, P Huck, T J Humanic, G Igo, W W Jacobs, H Jang, K Jiang, E G Judd, S Kabana, D Kalinkin, K Kang, K Kauder, H W Ke, D Keane, A Kechechyan, Z H Khan, D P Kikoła, I Kisel, A Kisiel, L Kochenda, D D Koetke, T Kollegger, L K Kosarzewski, A F Kraishan, P Kravtsov, K Krueger, I Kulakov, L Kumar, R A Kycia, M A C Lamont, J M Landgraf, K D Landry, J Lauret, A Lebedev, R Lednicky, J H Lee, Z M Li, W Li, X Li, X Li, C Li, Y Li, M A Lisa, F Liu, T Ljubicic, W J Llope, M Lomnitz, R S Longacre, X Luo, Y G Ma, G L Ma, L Ma, R Ma, N Magdy, R Majka, A Manion, S Margetis, C Markert, H Masui, H S Matis, D McDonald, K Meehan, N G Minaev, S Mioduszewski, D Mishra, B Mohanty, M M Mondal, D A Morozov, M K Mustafa, B K Nandi, Md Nasim, T K Nayak, G Nigmatkulov, L V Nogach, S Y Noh, J Novak, S B Nurushev, G Odyniec, A Ogawa, K Oh, V Okorokov, D Olvitt, B S Page, R Pak, Y X Pan, Y Pandit, Y Panebratsev, B Pawlik, H Pei, C Perkins, A Peterson, P Pile, M Planinic, J Pluta, N Poljak, K Poniatowska, J Porter, M Posik, A M Poskanzer, J Putschke, H Qiu, A Quintero, S Ramachandran, R Raniwala, S Raniwala, R L Ray, H G Ritter, J B Roberts, O V Rogachevskiy, J L Romero, A Roy, L Ruan, J Rusnak, O Rusnakova, N R Sahoo, P K Sahu, I Sakrejda, S Salur, J Sandweiss, A Sarkar, J Schambach, R P Scharenberg, A M Schmah, W B Schmidke, N Schmitz, J Seger, P Seyboth, N Shah, E Shahaliev, P V Shanmuganathan, M Shao, B Sharma, M K Sharma, W Q Shen, S S Shi, Q Y Shou, E P Sichtermann, R Sikora, M Simko, S Singha, M J Skoby, D Smirnov, N Smirnov, L Song, P Sorensen, H M Spinka, B Srivastava, T D S Stanislaus, M Stepanov, R Stock, M Strikhanov, B Stringfellow, M Sumbera, B Summa, X Sun, X M Sun, Y Sun, Z Sun, B Surrow, N Svirida, M A Szelezniak, A H Tang, Z Tang, T Tarnowsky, A Tawfik, J H Thomas, A R Timmins, D Tlusty, M Tokarev, S Trentalange, R E Tribble, P Tribedy, S K Tripathy, B A Trzeciak, O D Tsai, T Ullrich, D G Underwood, I Upsal, G Van Buren, G van Nieuwenhuizen, M Vandenbroucke, R Varma, A N Vasiliev, R Vertesi, F Videbæk, Y P Viyogi, S Vokal, S A Voloshin, A Vossen, Y Wang, G Wang, J S Wang, H Wang, Y Wang, F Wang, J C Webb, G Webb, L Wen, G D Westfall, H Wieman, S W Wissink, R Witt, Y F Wu, Y Wu, Z G Xiao, W Xie, K Xin, N Xu, Z Xu, Q H Xu, Y F Xu, H Xu, Q Yang, Y Yang, Y Yang, S Yang, C Yang, Z Ye, P Yepes, L Yi, K Yip, I-K Yoo, N Yu, H Zbroszczyk, W Zha, Z Zhang, Y Zhang, J B Zhang, J Zhang, S Zhang, J Zhang, X P Zhang, J Zhao, C Zhong, L Zhou, X Zhu, Y Zoulkarneeva, M Zyzak
We present high precision measurements of elliptic flow near midrapidity (|y|<1.0) for multistrange hadrons and ϕ meson as a function of centrality and transverse momentum in Au+Au collisions at center of mass energy √[sNN]=200  GeV. We observe that the transverse momentum dependence of ϕ and Ω v2 is similar to that of π and p, respectively, which may indicate that the heavier strange quark flows as strongly as the lighter up and down quarks. This observation constitutes a clear piece of evidence for the development of partonic collectivity in heavy-ion collisions at the top RHIC energy...
February 12, 2016: Physical Review Letters
https://www.readbyqxmd.com/read/26852864/interaction-of-peptide-transporter-1-with-d-glucose-and-l-glutamic-acid-possible-involvement-of-taste-receptors
#14
Hiroshi Arakawa, Taichi Ohmachi, Kiko Ichiba, Hiroki Kamioka, Takumi Tomono, Masahiko Kanagawa, Yoko Idota, Yasuko Hatano, Kentaro Yano, Kaori Morimoto, Takuo Ogihara
We investigated the influence of sweet and umami (savory) tastants on the intestinal absorption of cephalexin (CEX), a substrate of peptide transporter 1 (PEPT1, SLC15A1) in rats. After oral administration of glucose or mannitol to rats, CEX was administered together with a second dose of glucose or mannitol. Western blot analysis indicated that expression of PEPT1 in rat jejunum membrane was decreased by glucose, compared to mannitol. Furthermore, the maximum plasma concentration (Cmax) of orally administered CEX was reduced by glucose compared to mannitol...
January 2016: Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/26778666/evaluation-of-conjunctival-bacterial-flora-in-a-herd-of-goats-in-the-midwestern-united-states
#15
Jessica M Meekins, Michael D Apley, Brian Lubbers, Lalitha Peddireddi, Amy J Rankin
OBJECTIVE: To identify conjunctival bacterial flora in healthy adult and newborn kid goats in the Midwestern United States and to compare vaginal and ocular surface flora in dam-kid pairs. ANIMALS STUDIED: Thirty mixed-breed (crosses between Boer, Kiko, and Syfan Spanish) goats, 20 adult does and 10 newborn kids. PROCEDURES: One eye of 15 adult goats (n = 15 eyes) and 5 kids (n = 5 eyes) was randomly selected. A subset of 5 adults (n = 10 eyes) and 5 kids (n = 10 eyes) underwent bilateral sampling...
January 2017: Veterinary Ophthalmology
https://www.readbyqxmd.com/read/26682681/alterations-in-the-levels-of-amyloid-%C3%AE-phospholipid-hydroperoxide-and-plasmalogen-in-the-blood-of-patients-with-alzheimer-s-disease-possible-interactions-between-amyloid-%C3%AE-and-these-lipids
#16
Shinji Yamashita, Takehiro Kiko, Hironori Fujiwara, Michio Hashimoto, Kiyotaka Nakagawa, Mikio Kinoshita, Katsutoshi Furukawa, Hiroyuki Arai, Teruo Miyazawa
Aside from accumulation of amyloid-β (Aβ) peptide in the brain, Alzheimer's disease (AD) has been reported as being associated with peroxidation of major phospholipids (e.g., phosphatidylcholine (PtdCho)) and degradation of antioxidative phospholipids (e.g., ethanolamine plasmalogen (PlsEtn)). In addition to its presence in the brain, Aβ is also found in blood; however, there is still little information about the levels of PtdCho hydroperoxide (PCOOH) and PlsEtn in the blood of patients with AD. In this study, by assuming a possible interaction among Aβ, PCOOH, and PlsEtn in blood circulation, we evaluated the levels of these molecules and correlations in blood samples that had been obtained from our former AD study for PCOOH measurement (Kiko et al...
2016: Journal of Alzheimer's Disease: JAD
https://www.readbyqxmd.com/read/26642040/a-new-family-of-anionic-fe-iii-spin-crossover-complexes-featuring-a-weak-field-n2o4-coordination-octahedron
#17
Kazuyuki Takahashi, Kiko Kawamukai, Mitsunobu Okai, Tomoyuki Mochida, Takahiro Sakurai, Hitoshi Ohta, Takashi Yamamoto, Yasuaki Einaga, Yoshihito Shiota, Kazunari Yoshizawa
Unprecedented anionic Fe(III) spin crossover (SCO) complexes involving a weak-field O,N,O-tridentate ligand were discovered. The SCO transition was evidenced by the temperature variations in magnetic susceptibility, Mössbauer spectrum, and coordination structure. The DFT calculations suggested that larger coefficients on the azo group in the HOMO-1 of a ligand might contribute to the enhancement of a ligand-field splitting energy. The present anionic SCO complex also exhibited the light- induced excited-spin-state trapping effect...
January 22, 2016: Chemistry: a European Journal
https://www.readbyqxmd.com/read/26512629/evolution-and-function-of-dinosaur-teeth-at-ultramicrostructural-level-revealed-using-synchrotron-transmission-x-ray-microscopy
#18
Chun-Chieh Wang, Yen-Fang Song, Sheng-Rong Song, Qiang Ji, Cheng-Cheng Chiang, Qingjin Meng, Haibing Li, Kiko Hsiao, Yi-Chia Lu, Bor-Yuan Shew, Timothy Huang, Robert R Reisz
The relationship between tooth form and dietary preference is a crucial issue in vertebrate evolution. However, the mechanical properties of a tooth are influenced not only by its shape but also by its internal structure. Here, we use synchrotron transmission X-ray microscopy to examine the internal microstructures of multiple dinosaur teeth within a phylogenetic framework. We found that the internal microstructures of saurischian teeth are very different from advanced ornithischian teeth, reflecting differences in dental developmental strategies...
October 29, 2015: Scientific Reports
https://www.readbyqxmd.com/read/26192623/aerobic-microbial-respiration-in-oceanic-oxygen-minimum-zones
#19
Tim Kalvelage, Gaute Lavik, Marlene M Jensen, Niels Peter Revsbech, Carolin Löscher, Harald Schunck, Dhwani K Desai, Helena Hauss, Rainer Kiko, Moritz Holtappels, Julie LaRoche, Ruth A Schmitz, Michelle I Graco, Marcel M M Kuypers
Oxygen minimum zones are major sites of fixed nitrogen loss in the ocean. Recent studies have highlighted the importance of anaerobic ammonium oxidation, anammox, in pelagic nitrogen removal. Sources of ammonium for the anammox reaction, however, remain controversial, as heterotrophic denitrification and alternative anaerobic pathways of organic matter remineralization cannot account for the ammonium requirements of reported anammox rates. Here, we explore the significance of microaerobic respiration as a source of ammonium during organic matter degradation in the oxygen-deficient waters off Namibia and Peru...
2015: PloS One
https://www.readbyqxmd.com/read/26141703/targeting-lipid-peroxidation-and-mitochondrial-imbalance-in-friedreich-s-ataxia
#20
Rosella Abeti, Ebru Uzun, Indhushri Renganathan, Tadashi Honda, Mark A Pook, Paola Giunti
Friedreich's ataxia (FRDA) is an autosomal recessive disorder, caused by reduced levels of the protein frataxin. This protein is located in the mitochondria, where it functions in the biogenesis of iron-sulphur clusters (ISCs), which are important for the function of the mitochondrial respiratory chain complexes. Moreover, disruption in iron biogenesis may lead to oxidative stress. Oxidative stress can be the cause and/or the consequence of mitochondrial energy imbalance, leading to cell death. Fibroblasts from two FRDA mouse models, YG8R and KIKO, were used to analyse two different categories of protective compounds: deuterised poly-unsaturated fatty acids (dPUFAs) and Nrf2-inducers...
September 2015: Pharmacological Research: the Official Journal of the Italian Pharmacological Society
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