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Elizabeth M La, Laurel Trantham, Samantha K Kurosky, Dawn Odom, Emmanuel Aris, Cosmina Hogea
Despite longstanding recommendations for routine vaccination against influenza; pneumococcal; tetanus, diphtheria, acellular pertussis (Tdap); and herpes zoster (HZ) among the United States general adult population, vaccine uptake remains low. Understanding factors that influence adult vaccination and coverage variability beyond the national level are important steps toward developing targeted strategies for increasing vaccination coverage. A retrospective analysis was conducted using data from the Behavioral Risk Factor Surveillance System (2011-2014)...
February 1, 2018: Human Vaccines & Immunotherapeutics
Melissa Berman, Eve Dubé, Caroline Quach
BACKGROUND: In children, the 13 and 10-valent pneumoccocal conjugate vaccines (PCV13/10) are currently approved for the prevention of invasive pneumococcal disease (IPD). Acceptability is a key consideration in the implementation of a vaccine program and it is recognized that health professional's attitudes and opinions towards vaccines are independent predictors of the success of an immunization program. We aimed to survey the beliefs and attitudes for the two available PCVs in health care professionals and immunization experts...
June 5, 2017: Vaccine
Jorge Rodríguez-Gómez, Rafael León, Juan Carlos Robles, Julián de la Torre-Cisneros
No abstract text is available yet for this article.
November 2016: Enfermedades Infecciosas y Microbiología Clínica
R Joshi Shashank, S Joshi Samika, N Shah Siddharth
Currently we have more than 65 million Diabetes patients in India with estimated 80 million prediabetics. Diabetes is a immunologically vulnerable population to develop all types of microbial infections. Pneumoccocal infections do have a substantial morbidity and mortality burden in the community. India has a large geriatric pool now which has substantially increased pneumococcal disease burden. Diabetes is a well-known risk factor for pneumococcal infection and predisposes individuals to nasopharyngeal colonization with the pneumococcus which is associated with invasive infection...
April 2015: Journal of the Association of Physicians of India
Güniz Yaşöz, Nurşen Belet, Gülnar Şensoy
The Bacille Calmette-Guérin (BCG) vaccine is used against tuberculosis. According to the vaccination program in Turkey, DaBT-Hib-IPV (diphtheriapertussis [acellular]-tetanus-haemophilus influenza type b-inactive poliovaccine), PVC13 (pneumoccocal conjugate vaccine) and BCG vaccines are given simultaneously to all 2-months-old infants, using different administration techniques. We report a 2-month-old infant who received an overdose and intramuscular BCG vaccine instead of DaBT-Hib-IPV. The patient was treated with isoniazid for six months and developed no complications during a oneyear follow-up period...
November 2014: Turkish Journal of Pediatrics
Nadia E Aikawa, Ivan L A França, Ana C Ribeiro, Adriana M E Sallum, Eloisa Bonfa, Clovis A Silva
OBJECTIVES: To assess immunogenicity and safety of the 23-valent polysaccharide pneumococcal vaccine (PPV23) in juvenile idiopathic arthritis (JIA) patients under conventional DMARDs with or without anti-TNF therapy. The influences of demographic data, disease activity and treatment on immune response and the potential deleterious effects of vaccine on disease itself were also evaluated. METHODS: 17 JIA patients immediately pre-etanercept (Group 1) and 10 JIA patients on stable dose of methotrexate (Group 2) received one dose of PPV23...
January 29, 2015: Vaccine
Ronaldo Abraham
The consequences of inflammatory response are primarily responsible for morbimortality in bacterial meningitis. Early use of steroids in these cases can reduce mortality and hearing loss and improve functional outcome without causing significant side effects. The formal recommendation towards pneumoccocal meningitis is being extended to other forms of Bacterial Meningitis. The same thought can be applied to tuberculous meningitis. In neurocysticercosis and neuroschistosomiasis steroids are more useful than parasiticides in most cases...
September 2013: Arquivos de Neuro-psiquiatria
Sandra Ribes, Jörn Riegelmann, Sandra Redlich, Beatriz Maestro, Bas de Waal, E W Meijer, Jesús M Sanz, Roland Nau
BACKGROUND: Pneumococcal virulence factors common to all serotypes, such as choline-binding proteins (CBPs), are promising therapeutic targets in pneumococcal infections. We studied the effect of a choline dendrimer with maximized binding affinity/specificity for CBPs on microglia-mediated pneumococcal phagocytosis. METHODS: Pneumoccocal cultures were exposed to dendrimers containing 8 choline end groups or amino groups as controls, either from the beginning of bacterial growth or at the late exponential phase...
2013: Chemotherapy
Gilda T Toraño Peraza, Rafael Llanes Caballero, Lisania M Pías Solis, Miriam Abreu Capote, Marlén Valcárcel Sánchez
INTRODUCTION: since 2006 in Cuba, there has been difficult to determine the actual incidente of bacterial meningitis and other invasive diseases caused by Streptococcus pneumoniae, as a result of the low percentage of isolation and identification of this agent in the domestic microbiology lab network. OBJECTIVE: to warn of the need of revitalizing the active surveillance of invasive, epidemiological and microbiological pneumoccocic diseases, mainly meningitis and pneumoniae in the phase prior to vaccination...
May 2010: Revista Cubana de Medicina Tropical
Hortensia Zelaya, Jonathan Laiño, Cecilia Haro, Susana Alvarez, Graciela Agüero
We studied the systemic effects of the intranasal administration of Lactobacillus casei on the immuno-coagulative response in pneumoccocal infection in immunocompromised mice. Weaned mice consumed a protein-free diet (PFD) for 21 days and were therefore malnourished. Malnourished mice were fed a balanced conventional diet (BCD) for 7 days (BCD group) or a BCD for 7 days with nasal administration of viable L. casei on days 6 and 7 (BCD+LcN group). The malnourished control mice (MNC) received a PFD, whereas the well-nourished control mice (WNC) continually consumed a BCD...
January 2013: Journal of Medical Microbiology
Mark van der Linden, Susanne Weiß, Gerhard Falkenhorst, Annette Siedler, Matthias Imöhl, Rüdiger von Kries
INTRODUCTION: Vaccination with pneumococcal conjugate vaccine (PCV) for all children <2 years was recommended in Germany in July 2006. Initially PCV7 was exclusively used; PCV10 became available from April 2009 and PCV7 was replaced by PCV13 in December 2009. OBJECTIVE: To compare the incidence and serotype distribution of invasive pneumococcal disease (IPD) for pneumococcal meningitis and non-meningitis IPD in children from 2007 to 2010 with reference to the pre-vaccination period from 1997 to 2001...
August 31, 2012: Vaccine
Badria Rashid Al Waili, Suleiman Alola, Esam Albanyan
Streptococcus pneumoniae (pneumococcus) is a bacterial pathogen that causes invasive infections, including septicemia and meningitis, as well as noninvasive infections such as community-acquired pneumonia, sinusitis and acute otitis media. Vaccination with pneumococcal conjugate vaccine (PCV7) has significantly reduced the burden of pneumococcal disease; however it targets only seven of the more than 92 pneumococcal serotypes. Concerns have been raised that nonvaccine serotypes could increase in prevalence and reduce the benefits of vaccination...
July 2013: Annals of Saudi Medicine
Mark H Rozenbaum, Cornelis Boersma, Maarten J Postma, Eelko Hak
Healthcare decisions on vaccination programs mainly rely on the direct burden of illness and related costs of the disease. Next to the expected direct beneficial effect of pediatric immunization programs against Streptococcus pneumoniae, worldwide implementation of these programs has also been driven by the indirect beneficial impact as observed among various nontargeted age groups in Northern America. In this article, we provide a descriptive overview of the post-marketing surveillance and show that there are large differences in the observed disease epidemiology after implementation of pediatric pneumococcal immunization programs across countries...
February 2011: Expert Review of Vaccines
H Trotman, O Olugbuyi, M Barton, D McGregor, S Thomas
OBJECTIVE: To describe the clinical features and outcome of pneumococcal meningitis in Jamaican children. METHODS: All patients admitted to the Bustamante Hospital for Children, during the period 1995-1999, who had pneumococcus isolated from cerebrospinal fluid (CSF) or pleocytosis in association with a blood culture isolate of pneumococcus were selected. Demographic, clinical and laboratory data were collected. RESULTS: Twenty-five (23%) of 111 patients with pneumococcal infections satisfied criteria for meningitis...
December 2009: West Indian Medical Journal
E Vintiñi, J Villena, S Alvarez, M Medina
Streptococcus pneumoniae is a serious public health problem, especially in developing countries, where available vaccines are not part of the vaccination calendar. We evaluated different respiratory mucosa immunization protocols that included the nasal administration of Lactococcus lactis-pneumococcal protective protein A (PppA) live, inactivated, and in association with a probiotic (Lc) to young mice. The animals that received Lc by the oral and nasal route presented the highest levels of immunoglobulin (Ig)A and IgG anti-PppA antibodies in bronchoalveolar lavages (BAL) and IgG in serum, which no doubt contributed to the protection against infection...
March 2010: Clinical and Experimental Immunology
Bernadetta Moser, Barbara Farina, Peter Zanon, Georg Röggla
No abstract text is available yet for this article.
2009: Wiener Klinische Wochenschrift
Maria Esteve Comas, Carme Loras Alastruey, Fernando Fernandez-Bañares
The mortality in inflammatory bowel disease (IBD) has been reported similar or slightly increased as compared to that of the general population. However, deaths related to infectious and parasitic diseases have been repeatedly reported in clinical trials, open series and registries. The IBD patients are exposed to the same infections affecting the community, added to opportunistic infectious related to the immunosuppression. Some of these infectious diseases may be prevented by the appropriate use of a vaccination program...
2009: Digestive Diseases
Balázs Ivády, Mónika Pásztor
UNLABELLED: Acute otitis media is one of the most common diseases in children aged 0-24 months and Streptococcus pneumoniae is the most frequently isolated bacterial pathogen of acute otitis media. It is well established and documented that the heptavalent pneumococcal conjugate vaccine reduces the frequency of otitis media, especially caused by vaccine-serotype pneumococcus (4, 6B, 9, 14, 18C, 19F, 23F). However, this effect depends on the serotype distribution of isolated otopathogenic pneumococcal strains...
May 17, 2009: Orvosi Hetilap
Paula Duchet-Niedziolka, Thomas Hanslik, Achille Aouba, Véronique Le Guern, Loïc Guillevin, Odile Launay
Patients with systemic autoimmune and/or inflammatory diseases have an increased risk of infections, particularly pneumoccocal invasive infections. Vaccination can prevent these infections. Available data about immunogenicity and safety of pneumococcal polysaccharide vaccine in these patients indicate that, it remains well tolerated and most of the time immunogenic, even if the antibody response is lower compared to healthy controls. These data encourage to vaccinate these patients with pneumococcal vaccine...
February 2009: La Presse Médicale
William S Pearson, Shanta R Dube, Earl S Ford, Ali H Mokdad
OBJECTIVE: Smoking is associated with increased risk for respiratory infections. The objective of this study was to determine if differences in influenza and pneumoccocal vaccination rates exist based on smoking status. METHODS: Data from the 2006 Behavior Risk Fact Surveillance System (BRFSS) were used to examine Influenza vaccinations among respondents 50-years-old and older (n=198,500) and pneumococcal vaccinations among adults 65-years-old and older (n=61,894)...
February 2009: Preventive Medicine
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