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https://www.readbyqxmd.com/read/29352346/the-evolution-of-breast-reduction-publications-a-bibliometric-analysis
#1
Ümran Muslu
OBJECTIVE: This study aims to make a bibliometric analysis of the studies on breast reduction (BR) between the years 1980 and 2016 and identify important studies through trend topics as well as active authors, countries, universities, scientific journals, and citation and co-citation analyses about BR. BACKGROUND: Although BR looks like one of the cosmetic surgeries performed in order to restore the woman's appearance, in fact it is a reconstructive surgery that eliminates back pain, stance disorder, headache, shoulder pain, back and cervical disk hernia, difficulty in breathing, hollowness caused by bra straps, hygiene problems under breasts (e...
January 19, 2018: Aesthetic Plastic Surgery
https://www.readbyqxmd.com/read/29351574/self-reported-knowledge-correct-knowledge-and-use-of-uk-drinking-guidelines-among-a-representative-sample-of-the-english-population
#2
Penny Buykx, Jessica Li, Lucy Gavens, Lucie Hooper, Elena Gomes de Matos, John Holmes
Aims: Promotion of lower risk drinking guidelines is a commonly used public health intervention with various purposes, including communicating alcohol consumption risks, informing drinkers' decision-making and, potentially, changing behaviour. UK drinking guidelines were revised in 2016. To inform potential promotion of the new guidelines, we aimed to examine public knowledge and use of the previous drinking guidelines, including by population subgroup. Methods: A demographically representative, cross-sectional online survey of 2100 adults living in England in July 2015 (i...
January 17, 2018: Alcohol and Alcoholism: International Journal of the Medical Council on Alcoholism
https://www.readbyqxmd.com/read/29344378/clinical-outcomes-and-costs-of-cardiac-revascularisation-in-england-and-new-york-state
#3
Francisco Leyva, Tian Qiu, Felicity Evison, Christopher Christoforou, David McNulty, Peter Ludman, Daniel Ray
Objectives: Healthcare expenditure per-capita in the USA is higher than in England. We hypothesised that clinical outcomes after cardiac revascularisation are better in the USA. We compared costs and outcomes of patients undergoing coronary artery bypass grafting (CABG) and percutaneous coronary intervention (PCI) in England and New York State (NYS). Methods: Costs and total mortality were assessed using the Hospital Episode Statistics for England and the Statewide Planning and Research Cooperative System for NYS...
2018: Open Heart
https://www.readbyqxmd.com/read/29342304/introduction-of-standardised-tobacco-packaging-during-a-12-month-transition-period-findings-from-small-retailers-in-the-united-kingdom
#4
Nathan Critchlow, Martine Stead, Crawford Moodie, Douglas Eadie, Anne Marie MacKintosh
Introduction: Factory-made cigarettes (FMC) and roll-your-own (RYO) tobacco have had to be produced in standardised packaging since 20th May 2016 in the United Kingdom, with a minimum pack size of 20 sticks for FMC and 30 grams for RYO. Manufacturers and retailers were given a 12-month transition period. Methods: An observational study was conducted using monthly Electronic Point of Sale data from 500 small retailers in England, Scotland, and Wales, between May 2016 and May 2017...
January 12, 2018: Nicotine & Tobacco Research: Official Journal of the Society for Research on Nicotine and Tobacco
https://www.readbyqxmd.com/read/29341109/the-prescribable-drugs-with-efficacy-in-experimental-epilepsies-pde3-database-for-drug-repurposing-research-in-epilepsy
#5
Shayeeshan Sivapalarajah, Mathangi Krishnakumar, Harry Bickerstaffe, YikYing Chan, Joseph Clarkson, Alistair Hampden-Martin, Ahmad Mirza, Matthew Tanti, Anthony Marson, Munir Pirmohamed, Nasir Mirza
OBJECTIVE: Current antiepileptic drugs (AEDs) have several shortcomings. For example, they fail to control seizures in 30% of patients. Hence, there is a need to identify new AEDs. Drug repurposing is the discovery of new indications for approved drugs. This drug "recycling" offers the potential of significant savings in the time and cost of drug development. Many drugs licensed for other indications exhibit antiepileptic efficacy in animal models. Our aim was to create a database of "prescribable" drugs, approved for other conditions, with published evidence of efficacy in animal models of epilepsy, and to collate data that would assist in choosing the most promising candidates for drug repurposing...
January 17, 2018: Epilepsia
https://www.readbyqxmd.com/read/29336101/recurrence-of-vulval-intraepithelial-neoplasia-following-treatment-with-cidofovir-or-imiquimod-results-from-a-multi-centre-randomised-phase-ii-trial-rt3vin
#6
Christopher N Hurt, Sadie E F Jones, Tracie-Ann Madden, Alison Fiander, Andrew J Nordin, Raj Naik, Ned Powell, Margherita Carucci, Amanda Tristram
OBJECTIVE: To compare the recurrence rates after complete response to topical treatment with either cidofovir or imiquimod for vulval intraepithelial neoplasia (VIN) 3. DESIGN: A prospective, open, randomised multicentre trial. SETTING: 32 general hospitals located in Wales and England. POPULATION OR SAMPLE: 180 patients were randomised consecutively between Oct 21, 2009, and Jan 11, 2013, 89 to cidofoovir (of whom 41 completely responded to treatment) and 91 to imiquimod (of whom 42 completely responded to treatment)...
January 16, 2018: BJOG: An International Journal of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/29335161/health-equity-monitoring-for-healthcare-quality-assurance
#7
R Cookson, M Asaria, S Ali, R Shaw, T Doran, P Goldblatt
Population-wide health equity monitoring remains isolated from mainstream healthcare quality assurance. As a result, healthcare organizations remain ill-informed about the health equity impacts of their decisions - despite becoming increasingly well-informed about quality of care for the average patient. We present a new and improved analytical approach to integrating health equity into mainstream healthcare quality assurance, illustrate how this approach has been applied in the English National Health Service, and discuss how it could be applied in other countries...
January 6, 2018: Social Science & Medicine
https://www.readbyqxmd.com/read/29329657/the-development-and-trial-of-an-unmanned-aerial-system-for-the-measurement-of-methane-flux-from-landfill-and-greenhouse-gas-emission-hotspots
#8
Grant Allen, Peter Hollingsworth, Khristopher Kabbabe, Joseph R Pitt, Mohammed I Mead, Samuel Illingworth, Gareth Roberts, Mark Bourn, Dudley E Shallcross, Carl J Percival
This paper describes the development of a new sampling and measurement method to infer methane flux using proxy measurements of CO2 concentration and wind data recorded by Unmanned Aerial Systems (UAS). The flux method described and trialed here is appropriate to the spatial scale of landfill sites and analogous greenhouse gas emission hotspots, making it an important new method for low-cost and rapid case study quantification of fluxes from currently uncertain (but highly important) greenhouse gas sources...
January 9, 2018: Waste Management
https://www.readbyqxmd.com/read/29329525/reporting-of-heterogeneity-of-treatment-effect-in-cohort-studies-a-review-of-the-literature
#9
Meryl Dahan, Caroline Scemama, Raphael Porcher, David J Biau
BACKGROUND: This article corresponds to a literature review and analyze how heterogeneity of treatment (HTE) is reported and addressed in cohort studies and to evaluate the use of the different measures to HTE analysis. METHODS: prospective cohort studies, in English language, measuring the effect of a treatment (pharmacological, interventional, or other) published among 119 core clinical journals (defined by the National Library of Medicine) in the last 16 years were selected in the following data source: Medline...
January 12, 2018: BMC Medical Research Methodology
https://www.readbyqxmd.com/read/29326327/national-roll-out-of-latent-tuberculosis-testing-and-treatment-for-new-migrants-in-england-a-retrospective-evaluation-in-a-high-incidence-area
#10
Miranda G Loutet, Matthew Burman, Nivenka Jayasekera, Duncan Trathen, Susan Dart, Heinke Kunst, Dominik Zenner
Latent tuberculosis infection (LTBI) screening is an important intervention for tuberculosis (TB) elimination in low-incidence countries and is, therefore, a key component of England's TB control strategy. This study describes outcomes from a LTBI screening programme in a high-incidence area to inform national LTBI screening in England and other low-incidence countries.We conducted a retrospective cohort study of LTBI screening among eligible migrants (from high-incidence countries and entered the UK within the last 5 years), who were identified at primary-care clinics in Newham, London between August 2014 and August 2015...
January 2018: European Respiratory Journal: Official Journal of the European Society for Clinical Respiratory Physiology
https://www.readbyqxmd.com/read/29322613/forward-view-advancing-health-library-and-knowledge-services-in-england
#11
Sue Lacey Bryant, Helen Bingham, Ruth Carlyle, Alison Day, Linda Ferguson, David Stewart
This article is the fourth in a series on New Directions. The National Health Service is under pressure, challenged to meet the needs of an ageing population, whilst striving to improve standards and ensure decision making is underpinned by evidence. Health Education England is steering a new course for NHS library and knowledge services in England to ensure access to knowledge and evidence for all decision makers. Knowledge for Healthcare calls for service transformation, role redesign, greater coordination and collaboration...
January 10, 2018: Health Information and Libraries Journal
https://www.readbyqxmd.com/read/29320891/the-political-economy-of-the-assessment-of-value-of-new-health-technologies
#12
Jonathan Karnon, Laura Edney, Hossein Afzali
Health technology assessment provides a common framework for evaluating the costs and benefits of new health technologies to inform decisions on the public funding of new pharmaceuticals and other health technologies. In Australia and England, empirical analyses of the opportunity costs of government spending on new health technologies suggest more quality adjusted life years are being forgone than are being gained by a non-trivial proportion of funded health technologies. This essay considers the relevance of available empirical estimates of opportunity costs and explores the relationship between the public funding of health technologies and broader political and economic factors...
January 1, 2018: Journal of Health Services Research & Policy
https://www.readbyqxmd.com/read/29320658/osimertinib-as-first-line-treatment-in-egfr-mutated-non-small-cell-lung-cancer
#13
EDITORIAL
Sanjay Popat
New England Journal of Medicine, Volume 378, Issue 2, Page 192-193, January 2018.
January 11, 2018: New England Journal of Medicine
https://www.readbyqxmd.com/read/29320655/ivf-transfer-of-fresh-or-frozen-embryos-in-women-without-polycystic-ovaries
#14
Lan N Vuong, Vinh Q Dang, Tuong M Ho, Bao G Huynh, Duc T Ha, Toan D Pham, Linh K Nguyen, Robert J Norman, Ben W Mol
BACKGROUND: Among women who are undergoing in vitro fertilization (IVF), the transfer of frozen embryos has been shown to result in a higher rate of live birth than the transfer of fresh embryos in those with infertility associated with the polycystic ovary syndrome. It is not known whether frozen-embryo transfer results in similar benefit in women with infertility that is not associated with the polycystic ovary syndrome. METHODS: We randomly assigned 782 infertile women without the polycystic ovary syndrome who were undergoing a first or second IVF cycle to receive either a frozen embryo or a fresh embryo on day 3...
January 11, 2018: New England Journal of Medicine
https://www.readbyqxmd.com/read/29320654/immune-related-adverse-events-associated-with-immune-checkpoint-blockade
#15
Michael A Postow, Robert Sidlow, Matthew D Hellmann
New England Journal of Medicine, Volume 378, Issue 2, Page 158-168, January 2018.
January 11, 2018: New England Journal of Medicine
https://www.readbyqxmd.com/read/29320652/multiple-sclerosis
#16
Daniel S Reich, Claudia F Lucchinetti, Peter A Calabresi
New England Journal of Medicine, Volume 378, Issue 2, Page 169-180, January 2018.
January 11, 2018: New England Journal of Medicine
https://www.readbyqxmd.com/read/29320647/long-term-effects-of-inhaled-budesonide-for-bronchopulmonary-dysplasia
#17
Dirk Bassler, Eric S Shinwell, Mikko Hallman, Pierre-Henri Jarreau, Richard Plavka, Virgilio Carnielli, Christoph Meisner, Corinna Engel, Alexander Koch, Karen Kreutzer, Johannes N van den Anker, Matthias Schwab, Henry L Halliday, Christian F Poets
BACKGROUND: The long-term effects on neurodevelopment of the use of inhaled glucocorticoids in extremely preterm infants for the prevention or treatment of bronchopulmonary dysplasia are uncertain. METHODS: We randomly assigned 863 infants (gestational age, 23 weeks 0 days to 27 weeks 6 days) to receive early (within 24 hours after birth) inhaled budesonide or placebo. The prespecified secondary long-term outcome was neurodevelopmental disability among survivors, defined as a composite of cerebral palsy, cognitive delay (a Mental Development Index score of <85 [1 SD below the mean of 100] on the Bayley Scales of Infant Development, Second Edition, with higher scores on the scale indicating better performance), deafness, or blindness at a corrected age of 18 to 22 months...
January 11, 2018: New England Journal of Medicine
https://www.readbyqxmd.com/read/29320646/transfer-of-fresh-versus-frozen-embryos-in-ovulatory-women
#18
Yuhua Shi, Yun Sun, Cuifang Hao, Heping Zhang, Daimin Wei, Yunshan Zhang, Yimin Zhu, Xiaohui Deng, Xiujuan Qi, Hong Li, Xiang Ma, Haiqin Ren, Yaqin Wang, Dan Zhang, Bo Wang, Fenghua Liu, Qiongfang Wu, Ze Wang, Haiyan Bai, Yuan Li, Yi Zhou, Mei Sun, Hong Liu, Jing Li, Lin Zhang, Xiaoli Chen, Songying Zhang, Xiaoxi Sun, Richard S Legro, Zi-Jiang Chen
BACKGROUND: Elective frozen-embryo transfer has been shown to result in a higher live-birth rate than fresh-embryo transfer among anovulatory women with the polycystic ovary syndrome. It is uncertain whether frozen-embryo transfer increases live-birth rates among ovulatory women with infertility. METHODS: In this multicenter, randomized trial, we randomly assigned 2157 women who were undergoing their first in vitro fertilization cycle to undergo either fresh-embryo transfer or embryo cryopreservation followed by frozen-embryo transfer...
January 11, 2018: New England Journal of Medicine
https://www.readbyqxmd.com/read/29310993/consensus-methodology-to-determine-minor-ailments-appropriate-to-be-directed-for-management-within-community-pharmacy
#19
Hamde Nazar, Zachariah Nazar, Andre Yeung, Mike Maguire, Alex Connelly, Sarah P Slight
BACKGROUND: National Health Service (NHS) 111, a medical helpline for urgent care used within the England and Scotland, receives significant numbers of patient calls yearly for a range of clinical conditions. Some are considered high acuity and mainly directed to urgent and emergency care. Low acuity conditions are also directed to these costly, overburdened services. Community pharmacy is a recognised setting for effective low acuity condition management and could offer an alternative...
January 4, 2018: Research in Social & Administrative Pharmacy: RSAP
https://www.readbyqxmd.com/read/29310599/birthplace-choices-what-are-the-information-needs-of-women-when-choosing-where-to-give-birth-in-england-a-qualitative-study-using-online-and-face-to-face-focus-groups
#20
Lisa Hinton, Carol Dumelow, Rachel Rowe, Jennifer Hollowell
BACKGROUND: Current clinical guidelines and national policy in England support offering 'low risk' women a choice of birth setting. Options include: home, free-standing midwifery unit (FMU), alongside midwifery unit (AMU) or obstetric unit (OU). This study, which is part of a broader project designed to inform policy on 'choice' in relation to childbirth, aimed to provide evidence on UK women's experiences of choice and decision-making in the period since the publication of the Birthplace findings (2011) and new NICE guidelines (2014)...
January 8, 2018: BMC Pregnancy and Childbirth
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