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https://www.readbyqxmd.com/read/27914940/soluble-urokinase-type-plasminogen-activator-receptor-supar-in-patients-with-acute-pancreatitis-ap-progress-in-prediction-of-ap-severity
#1
Michal Lipinski, Alicja Rydzewska-Rosolowska, Andrzej Rydzewski, Malgorzata Cicha, Grazyna Rydzewska
BACKGROUND: Soluble urokinase-type plasminogen activator receptor (suPAR) is a glycoprotein secreted during inflammation and infections. Moreover, increased levels of suPAR are observed after hypoxia and ischaemia. The aim of the study was to assess whether suPAR could represent a useful marker of acute pancreatitis (AP) severity. PATIENTS AND METHODS: We have observed a cohort of 126 prospectively enrolled patients. Based on the presence of persistent organ failure (more than 48 h) and local complications (diagnosis of moderate AP [MSAP]), patients were classified into three groups: mild AP (MAP), moderate and severe AP (SAP)...
November 25, 2016: Pancreatology: Official Journal of the International Association of Pancreatology (IAP) ... [et Al.]
https://www.readbyqxmd.com/read/27882045/comparison-of-bisap-ranson-mctsi-and-apache-ii-in-predicting-severity-and-prognoses-of-hyperlipidemic-acute-pancreatitis-in-chinese-patients
#2
Lixin Yang, Jing Liu, Yun Xing, Lichuan Du, Jing Chen, Xin Liu, Jianyu Hao
In recent years, with the developing of living standard, hyperlipidemia becomes the second major reason of acute pancreatitis. It is important to predict the severity and prognosis at early stage of hyperlipidemic acute pancreatitis (HLAP). We compared the BISAP, Ranson, MCTSI, and APACHE II scoring system in predicting MSAP and SAP, local complications, and mortality of HLAP. A total of 326 diagnosed hyperlipidemic acute pancreatitis patients from August 2006 to July 2015 were studied retrospectively. Our result showed that all four scoring systems can be used to predict the severity, local complications, and mortality of HLAP...
2016: Gastroenterology Research and Practice
https://www.readbyqxmd.com/read/27586977/-the-role-of-four-criteria-in-assessment-of-the-severity-and-prognosis-of-hyperlipidemic-acute-pancreatitis
#3
L X Yang, L C Du, X Liu, J Chen, J Y Hao
OBJECTIVE: To explore the four criteria, including bedside index for severity in acute pancreatitis(BISAP), Ranson score, modified CT severity index(MCTSI) and acute physiology and chronic health evaluation scoring systemⅡ(APACHE Ⅱ) in assessment of severity and prognosis of hyperlipidemic acute pancreatitis. METHODS: A total of 326 patients with hyperlipidemic acute pancreatitis were studied retrospectively from August 2006 to July 2015. The discrepancy of the four criteria in assessment of severity and prognosis of hyperlipidemic acute pancreatitis was compared with chi-square test and receiver operating characteristic curve...
September 1, 2016: Zhonghua Nei Ke za Zhi [Chinese Journal of Internal Medicine]
https://www.readbyqxmd.com/read/27513835/urine-ngal-is-useful-in-the-clinical-evaluation-of-renal-function-in-the-early-course-of-acute-pancreatitis
#4
Mateusz Sporek, Agnieszka Gala-Błądzińska, Paulina Dumnicka, Małgorzata Mazur-Laskowska, Stanislas Kielczewski, Jerzy Walocha, Piotr Ceranowicz, Marek Kuźniewski, Jerzy Mituś, Beata Kuśnierz-Cabala
INTRODUCTION: Acute Kidney Injury (AKI) is a serious early complications in patients with acute pancreatitis (AP) that signifcantly increases mortality rates compared to patients without AKI. The early diagnosis of AKI during its treatable phases and implementation of appropriate treatment protocols can improve outcomes for this group of patients. A promising biomarker for AKI is neutrophil gelatinase-associated lipocalin (NGAL). AIM: This study evaluated the diagnostic value of NGAL concentrations in serum and in urine for patients developing AKI as an early complication of AP compared to AP patients without AKI...
2016: Folia Medica Cracoviensia
https://www.readbyqxmd.com/read/27459482/-early-diagnosis-of-mild-acute-pancreatitis
#5
A V Popov, D A Mineev, A I Ershova, N N Popova
AIM: to analyze the efficacy of early detection of patients with mild acute pancreatitis. MATERIAL AND METHODS: 61 patients with acute pancreatitis who do not require intensive care were analyzed. Severity of condition was assessed using integral scales, i.e. modified index of severe pancreatitis severity (MITOP), BISAP, HAPS, SOFA, SIRS, CTSI and Atlanta classification (2012). RESULTS: Verification of mild course of disease according to MITOP scores ≤0...
2016: Khirurgiia
https://www.readbyqxmd.com/read/27148850/stereotypical-metabolic-response-to-endoscopic-retrograde-cholangiopancreatography-show-alterations-in-pancreatic-function-regardless-of-post-procedure-pancreatitis
#6
Elizabeth R Lusczek, Kristen Colling, Sydne Muratore, Darwin Conwell, Martin Freeman, Greg Beilman
OBJECTIVES: Metabolomics-based diagnosis or prediction of risk may improve patient outcomes and improve understanding of the pathogenesis of acute pancreatitis (AP). Endoscopic retrograde cholangiopancreatography (ERCP) is a risk factor for developing AP. This pilot study examined metabolomes of patients before and after ERCP, hypothesizing that metabolomics could differentiate between patients who did and did not develop post-ERCP pancreatitis, and that biomarkers associated with development of AP could be identified...
May 5, 2016: Clinical and Translational Gastroenterology
https://www.readbyqxmd.com/read/27042605/differences-in-severity-and-outcomes-between-hypertriglyceridemia-and-alcohol-induced-pancreatitis
#7
Hemant Goyal, Betsy Smith, Chelsey Bayer, Carla Rutherford, Danielle Shelnut
BACKGROUND: Alcohol and hypertriglyceridemia (HTG) are among the most common causes of acute pancreatitis (AP) after gallstones. However, differences in severity at the time of presentation and outcomes have not been well-studied. OBJECTIVE: The aim of this study is to assess the differences between severity at presentation and outcomes of AP of hypertriglyceridemic and alcoholic origins. MATERIALS AND METHODS: A retrospective review of 177 patients who were discharged with diagnosis of AP was performed...
February 2016: North American Journal of Medical Sciences
https://www.readbyqxmd.com/read/26817077/-prognostic-significance-of-elements-of-the-multiorgan-insufficiency-syndrome-and-estimation-of-the-patients-state-severity-in-accordance-to-integral-scales-in-an-acute-necrotic-pancreatitis
#8
I V Khomyak, O V Rotar, V I Rotar, G G Petrovskiy
There were examined 113 patients, in whom an acute necrotic pancreatitis was diagnosed. While admittance to hospital a constant organ insufficiency was revealed in 50 (44%), a transient one--in 63 (56%) patients. In total 31 (27.4%) patients died. Respiratory insufficiency have occurred in 67% patients, and almost with similar rate--cardio-vascular (in 59%), renal (in 56%) and enteral (in 54%), dominating in the lethality structure. The BISAP (Bedcide Index for Severity in Acute Pancreatitis) scales applied permit with high probability to prognosticate the organ insufficiency and lethality in patients, suffering an acute necrotic pancreatitis...
September 2015: Klinichna Khirurhiia
https://www.readbyqxmd.com/read/26613249/evaluating-the-ability-of-the-bedside-index-for-severity-of-acute-pancreatitis-score-to-predict-severe-acute-pancreatitis-a-meta-analysis
#9
Yu-Xia Yang, Li Li
OBJECTIVE: To evaluate the diagnostic performance of the bedside index for severity in acute pancreatitis (BISAP) score in predicting severe acute pancreatitis (SAP). MATERIALS AND METHODS: A systematic search was conducted using PubMed, Cochrane library and EMBASE databases up to May 2014, and 9 related studies, including 1,972 subjects, were reviewed. Pooled sensitivity, specificity, positive likelihood ratio (PLR), negative likelihood ratio (NLR), diagnosis of odds ratio (DOR) and hierarchic summary receiver-operating characteristic (HSROC) curves, as well as the area under the HSROC curve (AUC), were assessed using the HSROC and bivariate mixed effects models...
2016: Medical Principles and Practice: International Journal of the Kuwait University, Health Science Centre
https://www.readbyqxmd.com/read/26513663/correction-the-value-of-bisap-score-for-predicting-mortality-and-severity-in-acute-pancreatitis-a-systematic-review-and-meta-analysis
#10
Wei Gao, Hong-Xia Yang, Cheng-En Ma
No abstract text is available yet for this article.
2015: PloS One
https://www.readbyqxmd.com/read/26201934/naso-jejunal-fluid-resuscitation-in-predicted-severe-acute-pancreatitis-randomized-comparative-study-with-intravenous-ringer-s-lactate
#11
RANDOMIZED CONTROLLED TRIAL
Vishal Sharma, Surinder S Rana, Ravi Sharma, Vinita Chaudhary, Rajesh Gupta, Deepak K Bhasin
INTRODUCTION: Early management of severe acute pancreatitis (SAP) includes intravenous fluid resuscitation. AIM: To confirm feasibility of naso-jejunal (NJ) fluid resuscitation using oral hydration solution (ORS) and compare its efficacy with intravenous (IV) fluid resuscitation using Ringer Lactate (RL) in predicted SAP. PATIENTS AND METHODS: All patients of predicted SAP (presence of SIRS or BISAP > 2) without significant co morbidities were randomized to NJ group (ORS: 20 ml/kg bolus and then 3 mL/kg/h) or IV group (RL infusion at same rate)...
January 2016: Journal of Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/26129965/a-study-of-radiological-scoring-system-evaluating-extrapancreatic-inflammation-with-conventional-radiological-and-clinical-scores-in-predicting-outcomes-in-acute-pancreatitis
#12
Vishal Sharma, Surinder S Rana, Ravi K Sharma, Mandeep Kang, Rajesh Gupta, Deepak K Bhasin
BACKGROUND: A number of scoring systems are available to predict prognosis in acute pancreatitis (AP). The aim of the study was to compare extra-pancreatic inflammation on computed tomography (CT) (EPIC score) and renal rim sign with clinical scores (BISAP, SIRS) and conventional CT severity index (CTSI) and modified CTSI (MCTSI) in predicting persistent organ failure (POF), intervention and mortality. METHODS: The demographic, clinical and radiographic data from patients with AP were retrospectively evaluated...
July 2015: Annals of Gastroenterology: Quarterly Publication of the Hellenic Society of Gastroenterology
https://www.readbyqxmd.com/read/26126430/a-study-of-radiological-scoring-system-evaluating-extrapancreatic-inflammation-with-conventional-radiological-and-clinical-scores-in-predicting-outcomes-in-acute-pancreatitis
#13
Vishal Sharma, Surinder S Rana, Ravi K Sharma, Mandeep Kang, Rajesh Gupta, Deepak K Bhasin
BACKGROUND: A number of scoring systems are available to predict prognosis in acute pancreatitis (AP). The aim of the study was to compare extra-pancreatic inflammation on computed tomography (CT) (EPIC score) and renal rim sign with clinical scores (BISAP, SIRS) and conventional CT severity index (CTSI) and modified CTSI (MCTSI) in predicting persistent organ failure (POF), intervention and mortality. METHODS: The demographic, clinical and radiographic data from patients with AP were retrospectively evaluated...
July 2015: Annals of Gastroenterology: Quarterly Publication of the Hellenic Society of Gastroenterology
https://www.readbyqxmd.com/read/26091293/the-value-of-bisap-score-for-predicting-mortality-and-severity-in-acute-pancreatitis-a-systematic-review-and-meta-analysis
#14
REVIEW
Wei Gao, Hong-Xia Yang, Cheng-En Ma
PURPOSE: The Bedside Index for Severity in Acute Pancreatitis (BISAP) score has been developed to identify patients at high risk for mortality or severe disease early during the course of acute pancreatitis. We aimed to undertake a meta-analysis to quantify the accuracy of BISAP score for predicting mortality and severe acute pancreatitis (SAP). MATERIALS AND METHODS: We searched the databases of Pubmed, Embase, and the Cochrane Library to identify studies using the BISAP score to predict mortality or SAP...
2015: PloS One
https://www.readbyqxmd.com/read/26081056/-early-evaluations-of-bisap-plus-c-reactive-protein-in-predicting-the-severity-of-acute-pancreatitis
#15
Jimin Zheng, Jian Zhang, Juncha Gao
OBJECTIVE: To explore the early evaluations of Bedside Index for Severity in Acute Pancreatitis (BISAP) plus C-reactive protein (CRP) in predicting the severity and prognosis of acute pancreatitis (AP). METHODS: A total of 114 cases of AP at our hospital over the last 2 years were retrospectively analyzed. The levels of amylase, serum glucose, serum calcium, CRP and D-dimer in 24 hours were measured. According to the evaluation standard, the scores of BISAP, acute physiology and chronic health evaluation (APACHE II), Ranson and computed tomography severity index (CTSI) were obtained...
March 31, 2015: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/26061329/comparison-of-existing-clinical-scoring-systems-in-predicting-severity-and-prognoses-of-hyperlipidemic-acute-pancreatitis-in-chinese-patients-a-retrospective-study
#16
COMPARATIVE STUDY
Lei Qiu, Rui Qing Sun, Rong Rong Jia, Xiu Ying Ma, Li Cheng, Mao Chun Tang, Yan Zhao
It is important to identify the severity of acute pancreatitis (AP) in the early course of the disease. Clinical scoring systems may be helpful to predict the prognosis of patients with early AP; however, few analysts have forecast the accuracy of scoring systems for the prognosis in hyperlipidemic acute pancreatitis (HLAP). The purpose of this study was to summarize the clinical characteristics of HLAP and compare the accuracy of conventional scoring systems in predicting the prognosis of HLAP. This study retrospectively analyzed all consecutively diagnosed AP patients between September 2008 and March 2014...
June 2015: Medicine (Baltimore)
https://www.readbyqxmd.com/read/26027276/-diagnostic-value-of-integral-scoring-systems-in-assessing-the-severity-of-acute-pancreatitis-and-patient-s-condition
#17
Y S Vinnik, S S Dunaevskaya, D A Antufrieva
OBJECTIVE: The aim of the study was to evaluate the diagnostic value of specific and nonspecific scoring systems Tolstoy-Krasnogorov score, Ranson, BISAP, Glasgow, MODS 2, APACHE II and CTSI, which used at urgent pancreatology for estimation the severity of acute pancreatitis and status of patient. METHODS: 1550 case reports of patients which had inpatient surgical treatment at Road clinical hospital at the station Krasnoyarsk from 2009 till 2013 were analyzed. Diagnosis of severe acute pancreatitis and its complications were determined based on anamnestic data, physical exami- nation, clinical indexes, ultrasonic examination and computed tomography angiography...
2015: Vestnik Rossiĭskoĭ Akademii Meditsinskikh Nauk
https://www.readbyqxmd.com/read/25875514/-bisap-o-y-apache-o-utility-in-predicting-severity-in-acute-pancreatitis-in-modified-atlanta-classification
#18
Agnetha Pérez Campos, Eduar Bravo Paredes, Ricardo Prochazka Zarate, Alejandro Bussalleu, José Pinto Valdivia, Vannessa Valenzuela Granados
OBJECTIVE: To assess the BISAP and APACHE II scores in predicting severity according to the 2012 Atlanta classification and whether the obesity factor added to these scores improves prediction. MATERIAL AND METHODS: A prospective study between January 2013 and April 2014 including all patients with acute pancreatitis was performed according to the new Atlanta 2012 classification. ROC curves were fabricated for BISAP, BISAP-O, APACHE-II scores and Apache O and appropriate cutoffs were selected to the sensitivity, specificity, PPV, NPV, RPP and RPN...
January 2015: Revista de Gastroenterología del Perú: órgano Oficial de la Sociedad de Gastroenterología del Perú
https://www.readbyqxmd.com/read/25843921/acute-pancreatitis-what-s-the-score
#19
REVIEW
Dick C Kuo, Ashley C Rider, Paul Estrada, Daniel Kim, Malford T Pillow
BACKGROUND: Acute pancreatitis (AP) is a common presentation in the emergency department (ED). Severity of pancreatitis is an important consideration for ED clinicians making admission judgments. Validated scoring systems can be a helpful tool in this process. OBJECTIVE: The aim of this review is to give a general outline on the subject of AP and compare different criteria used to predict severity of disease for use in the ED. DISCUSSION: This review updates the classifications and scoring systems for AP and the relevant parameters of each...
June 2015: Journal of Emergency Medicine
https://www.readbyqxmd.com/read/25741146/comparison-of-scoring-systems-in-predicting-the-severity-of-acute-pancreatitis
#20
COMPARATIVE STUDY
Joon Hyun Cho, Tae Nyeun Kim, Hyun Hee Chung, Kook Hyun Kim
AIM: To investigate the prognostic usefulness of several existing scoring systems in predicting the severity of acute pancreatitis (AP). METHODS: We retrospectively analyzed the prospectively collected clinical database from consecutive patients with AP in our institution between January 2011 and December 2012. Ranson, Acute Physiology and Chronic Health Evaluation (APACHE)-II, and bedside index for severity in acute pancreatitis (BISAP) scores, and computed tomography severity index (CTSI) of all patients were calculated...
February 28, 2015: World Journal of Gastroenterology: WJG
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