keyword
https://read.qxmd.com/read/37722072/contemporary-management-of-acute-pancreatitis-what-you-need-to-know
#21
JOURNAL ARTICLE
Rachael Palumbo, Kevin M Schuster
Acute pancreatitis and management of its complications is a common consult for the acute care surgeon. With the ongoing development of both operative and endoscopic treatment modalities, management recommendations continue to evolve. We describe the current diagnostic and treatment guidelines for acute pancreatitis through the lens of acute care surgery. Topics, including optimal nutrition, timing of cholecystectomy in gallstone pancreatitis, and the management of peripancreatic fluid collections, are discussed...
January 1, 2024: Journal of Trauma and Acute Care Surgery
https://read.qxmd.com/read/37658375/construction-and-validation-of-machine-learning-models-for-sepsis-prediction-in-patients-with-acute-pancreatitis
#22
RANDOMIZED CONTROLLED TRIAL
Fei Liu, Jie Yao, Chunyan Liu, Songtao Shou
BACKGROUND: This study aimed to construct predictive models for the risk of sepsis in patients with Acute pancreatitis (AP) using machine learning methods and compared optimal one with the logistic regression (LR) model and scoring systems. METHODS: In this retrospective cohort study, data were collected from the Medical Information Mart for Intensive Care III (MIMIC III) database between 2001 and 2012 and the MIMIC IV database between 2008 and 2019. Patients were randomly divided into training and test sets (8:2)...
September 1, 2023: BMC Surgery
https://read.qxmd.com/read/37608609/predictive-value-of-serum-retinol-binding-protein-in-severity-and-complications-of-acute-pancreatitis-a-retrospective-cohort-study
#23
JOURNAL ARTICLE
Xiao Han, Jianbo Ni, Bin Li, Jingpiao Bao, Rong Wan, Guoyong Hu, Congying Chen
OBJECTIVES: Retinol binding protein (RBP) is associated with an increased risk of insulin resistance, metabolic syndrome, atherosclerosis and hypertension. This study aimed to evaluate serum RBP levels in patients with acute pancreatitis (AP). METHODS: The study included 1,871 AP patients, including 1,411 with mild AP (MAP), 244 with moderately severe AP (MSAP), and 186 with severe AP (SAP). Retrospective analysis was conducted on RBP concentrations and other clinical data of AP patients...
August 22, 2023: Scandinavian Journal of Gastroenterology
https://read.qxmd.com/read/37577807/validation-of-the-revised-atlanta-criteria-in-determining-the-severity-of-acute-pancreatitis
#24
JOURNAL ARTICLE
Aysel Gürkan Toçoğlu, Aydin Şeref Köksal, Bilal Toka, Fuldem Mutlu, Ahmet Tarik Eminler, Mustafa İhsan Uslan, Erkan Parlak
BACKGROUND/AIM: Determining the severity of acute pancreatitis (AP) is crucial for patient management. The aim of our study was to assess the accuracy and limitations of the Revised Atlanta Criteria (RAC) in determining the severity of AP. MATERIALS AND METHODS: The study was retrospectively conducted on AP patients admitted to the Gastroenterology Department of Sakarya University Faculty of Medicine. The severity, morphology and local complications of AP were evaluated according to the RAC...
October 1, 2023: European Journal of Gastroenterology & Hepatology
https://read.qxmd.com/read/37553511/potential-value-of-red-blood-cell-distribution-width-in-predicting-in-hospital-mortality-in-intensive-care-us-population-with-acute-pancreatitis-a-propensity-score-matching-analysis
#25
JOURNAL ARTICLE
Shaoya He, Yu Shao, Tianyang Hu, Yanan Liu
The association between red blood cell distribution width (RDW) and in-hospital mortality in intensive care patients with acute pancreatitis (AP) is inconclusive. We extracted the baseline data, Bedside Index for Severity in Acute Pancreatitis (BISAP) score, Sequential Organ Failure Assessment (SOFA) score, and in-hospital prognosis of intensive care patients with AP from the Medical Information Mart for Intensive Care IV database. Performing binary logistic regression analysis to determine whether RDW is an independent risk factor for in-hospital mortality...
August 8, 2023: Scientific Reports
https://read.qxmd.com/read/37511976/decreased-hdl-c-levels-as-a-predictor-of-organ-failure-in-acute-pancreatitis-in-the-emergency-department
#26
JOURNAL ARTICLE
Ana Rocío Venegas-Tamayo, Olga Mariel Peña-Veites, Martha Alicia Hernández-González, Cornelio Barrientos-Alvarado
High-density lipoprotein cholesterol (HDL-C) is reported as a biomarker of systemic inflammation and multi-organ failure (MOF), which has been rarely investigated in acute pancreatitis (AP), a frequent condition in the emergency department (ED). The objective was to study the predictive capacity of the decrease in HDL-C to the progression of MOF in AP in the ED; analyzing 114 patients with AP for one year in a longitudinal and prospective study, AP severity was obtained by the Atlanta classification, in relation to modified Marshall and Bedside Index for Severity in Acute Pancreatitis (BISAP) scores, and clinical and laboratory parameters in a 48 h hospital stay...
July 21, 2023: Life
https://read.qxmd.com/read/37381808/the-utility-of-the-bedside-index-of-severity-in-acute-pancreatitis-at-prognosticating-adverse-outcomes
#27
JOURNAL ARTICLE
T N Makofane, D L Clarke, F Anderson, L Ferndale
BACKGROUND: Identification of at-risk patients with acute pancreatitis (AP) early on in the course of hospital admission remains a challenge. Early identification of these patients can facilitate early referral to tertiary hospitals with skilled multidisciplinary teams (MDTs) and high-dependency health care facilities. This study retrospectively reviewed the ability of the bedside index of severity in acute pancreatitis (BISAP) score and other biochemical markers to predict organ failure and mortality in acute pancreatitis...
June 2023: South African Journal of Surgery. Suid-Afrikaanse Tydskrif Vir Chirurgie
https://read.qxmd.com/read/37378221/comparing-prognostic-scores-and-inflammatory-markers-in-predicting-the-severity-and-mortality-of-acute-pancreatitis
#28
JOURNAL ARTICLE
Vasul Jain, Preetam Nath, Sudhir K Satpathy, Bandita Panda, Shubhransu Patro
BACKGROUND: Acute pancreatitis is an emergency gastrointestinal condition for which severity prediction is crucial during hospitalization. This study aimed to compare the diagnostic accuracy of inflammatory markers with gold standard scoring systems in predicting pancreatitis severity. MATERIALS AND METHODS: A prospective, hospital-based, cohort study was conducted, including 249 patients diagnosed with acute pancreatitis via clinical examination. Laboratory investigations and radiological investigations were conducted...
May 2023: Curēus
https://read.qxmd.com/read/37367946/comparison-of-the-imaging-and-clinical-characteristics-between-initial-and-recurrent-alcoholic-acute-pancreatitis-a-retrospective-cross-sectional-study
#29
JOURNAL ARTICLE
Wen-Han Xu, Xing-Hui Li, Ning-Jun Yu, Zhao Tang, Chao Chen, Chao Liu, Zeng-Hui Li, Xiao-Ming Zhang
MATERIALS: Patients with alcoholic acute pancreatitis in our hospital were recruited from Jan 2019 to July 2022 and divided into IAAP and RAAP groups. All patients underwent Contrast-Enhanced Computerized Tomography (CECT) or Magnetic Resonance Imaging (MRI) after administration. Imaging manifestations, local complications, severity scores on the Modified CT/MR Severity Index (MCTSI/MMRSI), Extrapancreatic Inflammation on CT/MR (EPIC/M), clinical severity [Bedside Index for Severity in Acute Pancreatitis (BISAP) Acute Physiology and Chronic Health Evaluation (APACHE-II)], and clinical prognosis were compared between the two groups...
June 27, 2023: American Journal of Drug and Alcohol Abuse
https://read.qxmd.com/read/37351008/development-and-validation-of-a-dynamic-nomogram-for-predicting-in-hospital-mortality-in-patients-with-acute-pancreatitis-a-retrospective-cohort-study-in-the-intensive-care-unit
#30
JOURNAL ARTICLE
Kang Zou, Shu Huang, Wensen Ren, Huan Xu, Wei Zhang, Xiaomin Shi, Lei Shi, Xiaolin Zhong, Yan Peng, Muhan Lü, Xiaowei Tang
PURPOSE: The aim of this study is to develop and validate a predictive model for the prediction of in-hospital mortality in patients with acute pancreatitis (AP) based on the intensive care database. PATIENTS AND METHODS: We analyzed the data of patients with AP in the Medical Information Mart for Intensive Care-IV (MIMIC-IV) database and Electronic Intensive Care Unit Collaborative Research Database (eICU-CRD). Then, patients from MIMIC-IV were divided into a development group and a validation group according to the ratio of 8:2, and eICU-CRD was assigned as an external validation group...
2023: International Journal of General Medicine
https://read.qxmd.com/read/37332769/a-modified-ranson-score-to-predict-disease-severity-organ-failure-pancreatic-necrosis-and-pancreatic-infection-in-patients-with-acute-pancreatitis
#31
JOURNAL ARTICLE
Xiuping Luo, Jie Wang, Qing Wu, Peng Peng, Guolin Liao, Chenghai Liang, Huiying Yang, Jiean Huang, Mengbin Qin
BACKGROUND: Although there are several scoring systems currently used to predict the severity of acute pancreatitis, each of them has limitations. Determine the accuracy of a modified Ranson score in predicting disease severity and prognosis in patients with acute pancreatitis (AP). METHODS: AP patients admitted or transferred to our institution were allocated to a modeling group ( n =  304) or a validation group ( n =  192). A modified Ranson score was determined by excluding the fluid sequestration parameter and including the modified computed tomography severity index (CTSI)...
2023: Frontiers in Medicine
https://read.qxmd.com/read/37329692/modified-bedside-index-for-severity-in-acute-pancreatitis-bisap-score-validation-in-the-national-inpatient-sample-database
#32
JOURNAL ARTICLE
Do Han Kim, Frank J Lukens, Donghyun Ko, Paul T Kröner, Miguel Salazar, Massimo Raimondo, Pedro Palacios Argueta
PURPOSE: The aim of this study was to build and validate modified score to be used in the healthcare cost and utilization project databases for further classification of acute pancreatitis (AP). MATERIALS AND METHODS: The National Inpatient Sample database for the years 2016-2019 was queried for all primary adult discharge diagnoses of AP. An mBISAP score system was created utilizing the ICD-10CM codes for pleural effusion, encephalopathy, acute kidney injury, systemic inflammatory response, and age >60...
June 15, 2023: Advances in Medical Sciences
https://read.qxmd.com/read/37308200/-application-of-machine-learning-model-based-on-xgboost-algorithm-in-early-prediction-of-patients-with-acute-severe-pancreatitis
#33
JOURNAL ARTICLE
Xin Gao, Jiaxi Lin, Airong Wu, Huiyuan Gu, Xiaolin Liu, Minyue Yin, Zhirun Zhou, Rufa Zhang, Chunfang Xu, Jinzhou Zhu
OBJECTIVE: To establish a machine learning model based on extreme gradient boosting (XGBoost) algorithm for early prediction of severe acute pancreatitis (SAP), and explore its predictive efficiency. METHODS: A retrospective cohort study was conducted. The patients with acute pancreatitis (AP) who admitted to the First Affiliated Hospital of Soochow University, the Second Affiliated Hospital of Soochow University and Changshu Hospital Affiliated to Soochow University from January 1, 2020 to December 31, 2021 were enrolled...
April 2023: Zhonghua Wei Zhong Bing Ji Jiu Yi Xue
https://read.qxmd.com/read/37303620/values-of-different-biochemical-indices-and-clinical-scoring-systems-for-the-assessment-of-acute-biliary-pancreatitis-in-a-chinese-population
#34
JOURNAL ARTICLE
Zhenyu Jia, Jie Xu, Yijie Gu, Lu Zheng, Tingting Xia
OBJECTIVE: To investigate values of biochemical indices and clinical scoring systems for the assessment of acute biliary pancreatitis (ABP). METHODS: Clinical characteristics, laboratory values including procalcitonin (PCT), and radiologic examinations of all ABP patients with mild acute pancreatitis (MAP), moderately severe acute pancreatitis (MSAP), or severe acute pancreatitis (SAP) were recorded within 48 hours after the onset of acute pancreatitis. Scores of the Accuracy of Acute Physiology and Chronic Health Evaluation (APACHE) II, Bedside Index of Severity in Acute Pancreatitis (BISAP), Computed Tomography Severity Index (CTSI), Ranson, Japanese Severity Score (JSS), Pancreatitis Outcome Prediction (POP) Score and Systemic Inflammatory Response Syndrome (SIRS) score were then calculated...
2023: American Journal of Translational Research
https://read.qxmd.com/read/37213160/expression-of-mir-25-3p-card9-and-surviving-in-acute-pancreatitis-and-predictive-value-for-patient-outcome
#35
JOURNAL ARTICLE
Nianfu Fang, Yuanjun Ding, Weisheng Yang
The clinical data of 246 patients with acute pancreatitis who met the inclusion and exclusion criteria in our hospital from May 2018 to May 2020 were collected as the modeling group, and 96 patients were used as the model validation group. To observe the expression of mir-25-3p, CARD9 and Survivin in patients with acute pancreatitis. To analyze the prognostic factors of acute pancreatitis by univariate and multivariate analysis, and to establish and validate the prognostic model of acute pancreatitis. Results: There was no significant difference in general data between the two groups (P>0...
January 31, 2023: Cellular and Molecular Biology
https://read.qxmd.com/read/37199713/predicting-in-hospital-mortality-in-patients-with-acute-pancreatitis-in-the-ed-a-direct-retrospective-comparison-of-four-clinical-and-radiological-prognostic-scores
#36
JOURNAL ARTICLE
Michele D Spampinato, Fabio Caputo, Matteo Guarino, Chiara Iantomasi, Francesco Luppi, Marcello Benedetto, Benedetta Perna, Andrea Portoraro, Angelina Passaro, Rinaldo Pellicano, Roberto DE Giorgio
BACKGROUND: Acute pancreatitis can be a severe disease that significantly impacts patients' quality of life and outcome. The clinical course is variable and predictive scoring systems have a debated role in early prognosis. This study aims to compare the prognostic accuracy of Balthazar, BISAP, HAPS and SOFA scores in the prediction of in-hospital mortality in patients with acute pancreatitis. METHODS: This is a retrospective, single-center cohort study conducted in the Emergency Department of a third-level university hospital...
May 18, 2023: Minerva gastroenterology
https://read.qxmd.com/read/37185028/position-of-surgical-treatment-in-step-up-management-of-severe-acute-pancreatitis
#37
JOURNAL ARTICLE
J Sedláčková, J Zajak, B Jon, J Maňák, S Rejchrt, F Čečka
INTRODUCTION: The incidence of acute pancreatitis has been increasing over the past twenty years and there is still no causal treatment available. Although cases of severe acute pancreatitis account for only about a fifth of all cases of acute pancreatitis, high morbidity and lethality call for an optimization and unification of treatment procedures. METHODS: We operated on 27 patients suffering from severe acute pancreatitis in the past five years. We compared selected parameters such as gender, age, body mass index, aetiology, presence of type 2 diabetes, BISAP score, previous minimally invasive treatment and presence of the intraabdominal compartment syndrome...
2023: Rozhledy V Chirurgii: Měsíčník Československé Chirurgické Společnosti
https://read.qxmd.com/read/37169033/acute-pancreatitis-due-to-hypertriglyceridemia-plasmapheresis-versus-medical-treatment
#38
JOURNAL ARTICLE
Gonca Koksaldi Sahin, Muge Gulen, Selen Acehan, Nurdan Unlu, Yilmaz Celik, Deniz Aka Satar, Mustafa Sencer Segmen, Salim Satar
OBJECTIVE: Hypertriglyceridemia (HTG) is the third-most common cause of acute pancreatitis. Plasmapheresis is an extracorporeal treatment method used for treatment. This study aimed to investigate the efficacy of medical treatment and plasmapheresis in patients with acute pancreatitis due to HTG. METHODS: This was a retrospective cross-sectional study. The patients were divided into two groups according to the treatment they received as those who received only medical treatment and those who performed plasmapheresis with medical treatment...
2023: Turkish Journal of Emergency Medicine
https://read.qxmd.com/read/37116044/to-evaluate-correlation-of-serum-copeptin-with-severity-of-liver-cirrhosis
#39
JOURNAL ARTICLE
Prashant Shankar, BaisThakur, Anita Rani
INTRODUCTION: Cirrhosis is defined as a diffuse process in the liver characterized by the development of extensive Fibrosis and replacement of the normal hepatic architecture by structurally abnormal nodules of fibrotic tissue. Because of its key role in circulatory homeostasis and its systemic vasoconstrictor effects AVP might be particularly interesting as a marker of circulatory dysfunction and prognosis in cirrhosis. Copeptin is secreted with AVP in equimolar amounts and strongly correlates with AVP over a wide range of osmolalities...
January 2023: Journal of the Association of Physicians of India
https://read.qxmd.com/read/37113191/early-predictive-value-of-scoring-systems-and-routine-laboratory-tests-in-severity-and-prognosis-of-acute-pancreatitis-in-pregnancy
#40
JOURNAL ARTICLE
Yu Wang, Guangbo Qu, Zhangbi Wu, Dongmei Tian, Wenbei Yang, Hongye Li, Yu Lu, GuangJun Meng, Hong Zhang
BACKGROUND: Currently, no guidelines specifically recommend scoring systems and biomarkers for early evaluation of the severity and prognosis of acute pancreatitis in pregnancy (APIP). OBJECTIVES: This study aimed to explore the early predictive value of scoring systems and routine laboratory tests on APIP severity and maternofetal prognosis. DESIGN: This study retrospectively analyzed 62 APIP cases in a 6-year period. METHODS: The predictive value of scoring systems and routine laboratory tests that were collected 24 h and 48 h after admission, for APIP severity and fetal loss, were analyzed...
2023: Therapeutic Advances in Gastroenterology
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