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L Prana, S Baijoob, B Rampersad
Introduction Intussuception remains one of the most common surgical abdominal emergencies in the paediatric population. The aim of this study was first to re-evaluate our non-operative reduction rate of intussusception using multiple interval barium enemas and second to investigate or discuss an audit cycle, providing evidence and validating the modification of clinical practice. Materials and methods This five-year retrospective study performed at one of two institutions at which a paediatric surgical service is offered...
March 15, 2018: Annals of the Royal College of Surgeons of England
Veena Hoffman, Remon Abu-Elyazeed, Cheryl Enger, Daina B Esposito, Michael C Doherty, Scott C Quinlan, Kathleen Skerry, Crystal N Holick, Peter Basile, Leonard R Friedland, Nicolas Praet, Stéphanie Wéry, Corinne Willame, David D Dore, Dominique Rosillon
As part of a regulatory commitment for post-licensure safety monitoring of live, oral human rotavirus vaccine (RV1), this study compared the incidence rates (IR) of intussusception, acute lower respiratory tract infection (LRTI) hospitalization, Kawasaki disease, convulsion, and mortality in RV1 recipients versus inactivated poliovirus vaccine (IPV) recipients in concurrent (cIPV) and recent historical (hIPV) comparison cohorts. Vaccine recipients were identified in 2 claims databases from August 2008 - June 2013 (RV1 and cIPV) and January 2004 - July 2008 (hIPV)...
March 13, 2018: Human Vaccines & Immunotherapeutics
Tagore Sunkara, Megan E Caughey, Andrea Culliford, Vinaya Gaduputi
Defined as the tunneling of one bowel segment into an adjacent bowel segment, intussusception is typically observed in pediatric populations. Here, we present the case of a 78-year-old man who, in a series of unlikely events, developed colonic intussusception due to a benign lead point pathology. Intussusception of the colon is an uncommon occurrence in adults. However, adult colonic intussusception, observed in the absence of a malignant lead point pathology, represents a true clinical anomaly.
January 4, 2018: Curēus
Chuan-Gao Xie, Xiao-Ming Xu, Shu-Mei Wei
BACKGROUND Multiple lymphomatous polyposis of the gastrointestinal tract can be associated with the B-cell lymphoma variant, mantle cell lymphoma, with most cases having been described in patients who are more than 50 years-of-age. A rare case of multiple lymphomatous polyposis due to mantle cell lymphoma is reported in a 34-year-old man. CASE REPORT A 34-year-old man presented with paroxysmal abdominal pain followed by spontaneous remission, which had been previously diagnosed as gastritis. An episode of ileocecal intussusception occurred, which was confirmed on imaging studies...
March 8, 2018: American Journal of Case Reports
V Piloni, M Bergamasco, G Melara, P Garavello
BACKGROUND: The aim of the present study was to assess the relationship between symptoms of obstructed defecation and findings on magnetic resonance (MR) defecography in males with obstructed defecation syndrome (ODS). METHODS: Thirty-six males with ODS who underwent MR defecography at our institution between March 2013 and February 2016 were asked in a telephone interview about their symptoms and subsequent treatment, either medical or surgical. Patients were divided into 2 groups, one with anismus (Group 1) and one with prolapse without anismus (Group 2)...
March 6, 2018: Techniques in Coloproctology
Tomohide Hori, Daiki Yasukawa, Takafumi Machimoto, Yoshio Kadokawa, Toshiyuki Hata, Tatsuo Ito, Shigeru Kato, Yuki Aisu, Yusuke Kimura, Yuichi Takamatsu, Taku Kitano, Tsunehiro Yoshimura
Full-thickness rectal prolapse (FTRP) is generally believed to result from a sliding hernia through a pelvic fascial defect, or from rectal intussusception. The currently accepted cause is a pelvic floor disorder. Surgery is the only definitive treatment, although the ideal therapeutic option for FTRP has not been determined. Auffret reported the first FTRP surgery using a perineal approach in 1882, and rectopexy using conventional laparotomy was first described by Sudeck in 1922. Laparoscopy was first used by Bermann in 1992, and laparoscopic surgery is now used worldwide; robotic surgery was first described by Munz in 2004...
March 2018: Annals of Gastroenterology: Quarterly Publication of the Hellenic Society of Gastroenterology
Fumiaki Kawano, Kousei Tashiro, Hironobu Nakao, Yoshirou Fujii, Takuto Ikeda, Shinsuke Takeno, Kunihide Nakamura, Atsushi Nanashima
INTRODUCTION: Jejunogastric intussusception is a rare complication after gastric operation. Intussusception after gastric operation occurs mostly at the gastrojejunal anastomosis site and Braun anastomosis site of Billroth II reconstruction, and at the Y anastomosis site of Roux-en-Y reconstruction. However, jejunogastric intussusception after distal gastrectomy with Roux-en-Y reconstruction is very rare. We report a surgical case of jejunogastric intussusception after distal gastrectomy for gastric cancer treatment...
January 31, 2018: International Journal of Surgery Case Reports
Zhang-Chun Hu, Ya-Lan Tan, Shun-Gen Huang, Peng Pan, Xiao-Bo Liu, Jian Wang, Wan-Liang Guo
We investigated the expression of Toll-like receptor 4 (TLR4) in the acute phase of intestinal I/R injury during intussusception and evaluated whether anti-TLR4 antibody-conjugated lead sulfide quantum dots (TLR4-PbS QDs) could be used to detect and monitor the injury. We first established a mouse model of I/R injury during intussusception. TLR-PbS QDs were then intravenously administered to intestinal I/R injured mice and visualized using whole-body fluorescence imaging in the second near-infrared window (NIR-II)...
January 30, 2018: Oncotarget
Lucio Díaz-Flores, Ricardo Gutiérrez, M ª Pino García, M González-Gómez, Francisco J Sáez, Lucio Díaz-Flores, José Luis Carrasco, Juan F Madrid
Sinusoidal hemangioma, characterized by interconnecting thin-walled vascular spaces, may present papillae/pseudo-papillae and zones that resemble intravascular papillary endothelial hyperplasia (IPEH). Our objectives are to explore the existence of zones in IPEH with sinusoidal hemangioma characteristics, the mechanism of papillary and septa formation in sinusoidal hemangioma and the comparison of this mechanism with that in IPEH. For these purposes, specimens of 4 cases of each entity were selected and studied by serial histologic sections and by immunochemistry and immunofluorescence procedures...
February 25, 2018: Acta Histochemica
V Kalliakmanis, I Perysinakis, K Koutsouvas, P Karras, E Margaris, C Angelakis
Intussusception is a rare cause of intestinal obstruction in adults and represents a diagnostic challenge for the surgeon. In the majority of cases, presenting symptoms are not specific, making preoperative diagnosis difficult. Several medical conditions may cause intestinal intussusception. We present the case of a 16-year-old female patient with intussusception due to a hamartomatous Peutz-Jeghers type polyp. This is an extremely rare case in which the first manifestation of the intestinal polyp was jejunojejunal intussusception very close to the duodenojejunal junction, with a necrotic intussusceptum about 50 cm long...
February 27, 2018: Annals of the Royal College of Surgeons of England
André Carvalho, Patrícia Leitão, Jorge Pinheiro, Margarida Sá Fernandes, Márcio Rodrigues, Ana Sofia Preto, Nuno Silva
Inflammatory fibroid polyps are rare, benign pseudotumors of the gastrointestinal tract of unknown etiology, which may rarely present as bowel intussusception and obstruction. The authors describe the clinical, radiologic, and pathologic features of 2 patients with ileal inflammatory fibroid polyps presenting as small bowel intussusception.
December 2017: Radiology Case Reports
Nicole Le Saux
The present statement provides information concerning the clinical rotavirus disease and rotavirus vaccines in Canada. Since the implementation of publically funded rotavirus vaccine programs in Canada, increasing evidence has been accumulating globally as to the effectiveness of rotavirus vaccines in the prevention of acute gastroenteritis. Current data estimate vaccine effectiveness to be in the order of 85% for preventing severe disease, including hospitalizations and emergency department visits, when vaccine coverage is high...
August 2017: Paediatrics & Child Health
Samiullah Khan, Shuai Su, Kui Jiang, Bang-Mao Wang
RATIONALE: Retrograde gastroesophageal intussusception (RGEI) is a relatively rare gastrointestinal (GI) disorder in which a portion of the stomach wall invaginates into the esophagus. More recently, peroral endoscopic myotomy (POEM) has emerged as an endoscopic alternative to surgical myotomy for achalasia, and, to the best of our knowledge, our case is the first RGEI after POEM to be reported. PATIENT CONCERNS: A 22-year-old male was presented with a history of vomiting, intractable retching and hematemesis for 3 days...
January 2018: Medicine (Baltimore)
Nguyen V Trang, Eleanor Burnett, Le H Ly, Nguyen P Anh, Pham H Hung, Hoang M Linh, Nguyen C T Trang, Tran M Canh, Vu T Minh, Jacqueline E Tate, Catherine Yen, Dang D Anh, Umesh D Parashar
In some settings, rotavirus vaccines have been associated with a low-level risk of intussusception, the most common cause of bowel obstruction in infants. As Vietnam prepares to introduce rotavirus vaccine into the national immunization program, we sought to better characterize the epidemiology of recurrent intussusception. We enrolled children <2 years of age who were hospitalized for intussusception retrospectively from January 2013 through December 2014 and prospectively from January 2015 through December 2016 at 2 hospitals in Vietnam...
February 22, 2018: Vaccine
Colin McQuade, Peadar S Waters, Ciara O'Brien, Stephen Crowther, William Torreggiani, Dara O Kavanagh
INTRODUCTION: Intussusception in adults is a rare condition, accounting for just 5% of all cases. Approximately 50% of cases of large intestine intussusception occur due to a malignant neoplasm. We present here a novel case report of colo-rectal intussusception arising secondary to a primary rectal melanoma. PRESENTATION OF CASE: We present the case of an 85 year-old patient, who underwent a colonoscopy for investigation of weight loss and altered bowel habit. At colonoscopy, a pigmented polypoid mass was visualised in the upper third of the rectum...
February 14, 2018: International Journal of Surgery Case Reports
Julie E Bines, Jarir At Thobari, Cahya Dewi Satria, Amanda Handley, Emma Watts, Daniel Cowley, Hera Nirwati, James Ackland, Jane Standish, Frances Justice, Gabrielle Byars, Katherine J Lee, Graeme L Barnes, Novilia S Bachtiar, Ajeng Viska Icanervilia, Karen Boniface, Nada Bogdanovic-Sakran, Daniel Pavlic, Ruth F Bishop, Carl D Kirkwood, Jim P Buttery, Yati Soenarto
BACKGROUND: A strategy of administering a neonatal rotavirus vaccine at birth to target early prevention of rotavirus gastroenteritis may address some of the barriers to global implementation of a rotavirus vaccine. METHODS: We conducted a randomized, double-blind, placebo-controlled trial in Indonesia to evaluate the efficacy of an oral human neonatal rotavirus vaccine (RV3-BB) in preventing rotavirus gastroenteritis. Healthy newborns received three doses of RV3-BB, administered according to a neonatal schedule (0 to 5 days, 8 weeks, and 14 weeks of age) or an infant schedule (8 weeks, 14 weeks, and 18 weeks of age), or placebo...
February 22, 2018: New England Journal of Medicine
Raymond Zhun Ming Lim, Terance Lee, Justin Yau Zane Ng, Kia Fatt Quek, Nyazirah Abdul Wahab, Shahrul Lokman Amansah, V Muthu Alhagi M Vellusamy, Chin Fang Ngim
BACKGROUND/PURPOSE: Although ultrasound-guided hydrostatic reduction (USGHR) is increasingly used in managing pediatric intussusception, there is limited literature concerning its use in Malaysia. We aim to examine the experience and factors associated with the effectiveness of USGHR using water. METHODS: This is a single-center retrospective observational study in a Malaysian tertiary referral center. Children with intussusception admitted between year 2012 and 2016 were included and medical records reviewed...
January 31, 2018: Journal of Pediatric Surgery
Sergey Leshchinskiy, Robert D'Agostino
No abstract text is available yet for this article.
February 16, 2018: Abdominal Radiology
Na Liu, Catherine Yen, Tao Huang, Pengwei Cui, Jacqueline E Tate, Baoming Jiang, Umesh D Parashar, Zhao-Jun Duan
INTRODUCTION: In China, rotavirus is the leading cause of diarrhea hospitalizations among children aged <5 years. A locally manufactured rotavirus vaccine is available for private market use, but little is known about its coverage. Given the impending availability of newer rotavirus vaccines, we evaluated intussusception rates among children aged <2 years to better understand intussusception epidemiology for future vaccine safety monitoring. METHODS: We conducted a retrospective review at 4 hospitals in Chenzhou City of Hunan Province and Kaifeng City of Henan Province...
February 10, 2018: Vaccine
Christine Y Louie, Adam J Gomez, Richard K Sibley, Dorsey Bass, Teri A Longacre
Immunoglobulin A (IgA) vasculitis or Henoch-Schönlein purpura (HSP) typically occurs in the pediatric population, although rare cases also occur in adults. Gastrointestinal (GI) involvement is common. The "classic" histologic finding in IgA vasculitis (HSP) is leukocytoclastic vasculitis (LCV); other histologic features in biopsies of IgA vasculitis (HSP) have only been rarely described. The pathology archival files at our institution were searched for GI biopsies from patients with IgA vasculitis (HSP)...
February 12, 2018: American Journal of Surgical Pathology
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