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Magnesium sulfate

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https://www.readbyqxmd.com/read/28703019/effectiveness-and-safety-of-magnesium-replacement-in-critically-ill-patients-admitted-to-the-medical-intensive-care-unit-in-an-academic-medical-center-a-retrospective-cohort-study
#1
Drayton A Hammond, Jelena Stojakovic, Niranjan Kathe, Julie Tran, Oktawia A Clem, Kristina Erbach, Jarrod King
BACKGROUND: "Rules of thumb" for the replacement of electrolytes, including magnesium, in critical care settings are used, despite minimal empirical validation of their ability to achieve a target serum concentration. This study's purpose was to evaluate the effectiveness and safety surrounding magnesium replacement in medically, critically ill patients with mild-to-moderate hypomagnesemia. METHODS: This was a single-center, retrospective, observational evaluation of episodes of intravenous magnesium replacement ordered for patients with mild-to-moderate hypomagnesemia (1...
January 1, 2017: Journal of Intensive Care Medicine
https://www.readbyqxmd.com/read/28694751/the-role-of-magnesium-sulfate-in-the-intensive-care-unit
#2
REVIEW
Yunes Panahi, Mojtaba Mojtahedzadeh, Atabak Najafi, Mohammad Reza Ghaini, Mohammad Abdollahi, Mohammad Sharifzadeh, Arezoo Ahmadi, Seyyed Mahdi Rajaee, Amirhossein Sahebkar
Magnesium (Mg) has been developed as a drug with various clinical uses. Mg is a key cation in physiological processes, and the homeostasis of this cation is crucial for the normal function of body organs. Magnesium sulfate (MgSO4) is a mineral pharmaceutical preparation of magnesium that is used as a neuroprotective agent. One rationale for the frequent use of MgSO4 in critical care is the high incidence of hypomagnesaemia in intensive care unit (ICU) patients. Correction of hypomagnesaemia along with the neuroprotective properties of MgSO4 has generated a wide application for MgSO4 in ICU...
2017: EXCLI journal
https://www.readbyqxmd.com/read/28692891/degradation-studies-of-quizalofop-p-and-related-compounds-in-soils-using-liquid-chromatography-coupled-to-low-and-high-resolution-mass-analyzers
#3
Rosalía López-Ruiz, Roberto Romero-González, José Luis Martínez Vidal, Manuel Fernández-Pérez, Antonia Garrido Frenich
A comprehensive degradation study of quizalofop-p, quizalofop-p-ethyl, quizalofop-p-tefuryl and propaquizafop in soil samples have been firstly performed using ultra high performance liquid chromatography coupled to Orbitrap mass spectrometry (UHPLC-Orbitrap-MS). Thus, metabolites or degradation products, such as CHHQ (dihydroxychloroquinoxalin), CHQ (6-chloroquinoxalin-2-ol), PPA ((R)-2-(4-hydroxyphenoxy)propionic acid) and 2,3-dihydroxyquinoxaline were also monitored. An extraction procedure based on QuEChERS procedure was used...
July 7, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28691718/additive-and-antagonistic-antinociceptive-interactions-between-magnesium-sulfate-and-ketamine-in-the-rat-formalin-test
#4
Katarina Savić Vujović, Sonja Vučković, Dolika Vasović, Branislava Medić, Nick Knežević, Milica Prostran
Because ketamine and magnesium block NMDA receptor activation by distinct mechanisms of action, we hypothesized that in a model of inflammatory pain in rats the combination of ketamine and magnesium might be more effective than ketamine alone. Antinociceptive activity was assessed by the formalin test in male Wistar rats (200-250 g). Animals were injected with 100 μL of 2.5% formalin to the plantar surface of the right hind paw. Data were recorded as the total time spent in pain-related behavior after the injection of formalin or vehicle (0...
2017: Acta Neurobiologiae Experimentalis
https://www.readbyqxmd.com/read/28690887/prevention-of-%C3%AE-radiation-induced-dna-damage-in-human-lymphocytes-using-a-serine-magnesium-sulfate-mixture
#5
Vahid Changizi, Mona Bahrami, Mahbod Esfahani, Seyed V Shetab-Boushehri
OBJECTIVES: Ionising radiation has deleterious effects on human cells. N-acetylcysteine (NAC) and cysteine, the active metabolite of NAC, are well-known radioprotective agents. Recently, a serine-magnesium sulfate combination was proposed as an antidote for organophosphate toxicity. This study aimed to investigate the use of a serine-magnesium sulfate mixture in the prevention of γ-radiation-induced DNA damage in human lymphocytes as compared to NAC and cysteine. METHODS: This study was carried out at the Iran University of Medical Sciences, Tehran, Iran, between April and September 2016...
May 2017: Sultan Qaboos University Medical Journal
https://www.readbyqxmd.com/read/28690617/transcriptomic-analysis-of-soil-grown-t-aestivum-cv-root-to-reveal-the-changes-in-expression-of-genes-in-response-to-multiple-nutrients-deficiency
#6
Saurabh Gupta, Brijesh S Yadav, Utkarsh Raj, Shiri Freilich, Pritish K Varadwaj
Deficiency of necessary macronutrients, i.e., Potassium (K), Magnesium (Mg), Nitrogen (N), Phosphorus (P), and Sulfate (S) in the soil leads to a reduction in plant growth and yield, which is a result of changes in expression level of various genes. This study was performed to identify the differentially expressed genes and its associated metabolic pathways occurred in soil grown wheat root samples excavated from the control and treated fields. To identify the difference in gene expression levels due to deficiency of the said nutrients, a transcriptomic, meta-analysis was performed on array expression profile data...
2017: Frontiers in Plant Science
https://www.readbyqxmd.com/read/28689331/pathophysiology-and-current-clinical-management-of-preeclampsia
#7
REVIEW
Lorena M Amaral, Kedra Wallace, Michelle Owens, Babbette LaMarca
Preeclampsia is characterized by blood pressure greater than 140/90 mmHg in the second half of pregnancy. This disease is a major contributor to preterm and low birth weight babies. The early delivery of the baby, which becomes necessary for maintaining maternal well-being, makes preeclampsia the leading cause for preterm labor and infant mortality and morbidity. Currently, there is no cure for this pregnancy disorder. The current clinical management of PE is hydralazine with labetalol and magnesium sulfate to slow disease progression and prevent maternal seizure, and hopefully prolong the pregnancy...
August 2017: Current Hypertension Reports
https://www.readbyqxmd.com/read/28689149/the-response-of-soil-and-stream-chemistry-to-decreases-in-acid-deposition-in-the-catskill-mountains-new-york-usa
#8
Michael R McHale, Douglas A Burns, Jason Siemion, Michael R Antidormi
The Catskill Mountains have been adversely impacted by decades of acid deposition, however, since the early 1990s, levels have decreased sharply as a result of decreases in emissions of sulfur dioxide and nitrogen oxides. This study examines trends in acid deposition, stream-water chemistry, and soil chemistry in the southeastern Catskill Mountains. We measured significant reductions in acid deposition and improvement in stream-water quality in 5 streams included in this study from 1992 to 2014. The largest, most significant trends were for sulfate (SO4(2-)) concentrations (mean trend of -2...
July 6, 2017: Environmental Pollution
https://www.readbyqxmd.com/read/28677612/crystal-structures-of-sodium-magnesium-selenate-decahydrate-na2mg-seo4-2%C3%A2-10h2o-a-new-selenate-salt-and-sodium-magnesium-selenate-dihydrate-na2mg-seo4-2%C3%A2-2h2o
#9
Stoyan Kamburov, Horst Schmidt, Wolfgang Voigt, Christo Balarew
Metal selenates crystallize in many instances in isomorphic structures of the corresponding sulfates. Sodium magnesium selenate decahydrate, Na2Mg(SeO4)2·10H2O, and sodium magnesium selenate dihydrate, Na2Mg(SeO4)2·2H2O, were synthesized by preparing solutions of Na2SeO4 and MgSeO4·6H2O with different molar ratios. The structures contain different Mg octahedra, i.e. [Mg(H2O)6] octahedra in the decahydrate and [MgO4(H2O)2] octahedra in the dihydrate. The sodium polyhedra are also different, i.e. [NaO2(H2O)4] in the decahydrate and [NaO6(H2O)] in the dihydrate...
July 1, 2017: Acta Crystallographica. Section C, Structural Chemistry
https://www.readbyqxmd.com/read/28674684/effect-of-fetal-sex-on-maternal-and-obstetric-outcomes
#10
REVIEW
Mohammed Al-Qaraghouli, Yu Ming Victor Fang
Fetal sex plays an important role in modifying the course and complications related to pregnancy and may also have an impact on maternal health and well-being both during and after pregnancy. The goal of this article is to review and summarize the findings from published research on physiologic and pathologic changes that may be affected by fetal sex and the effect of these changes on the maternal and obstetrical outcomes. This will help create awareness that fetal sex is not just a random chance event but an interactive process between the mother, the placenta, and the fetus...
2017: Frontiers in Pediatrics
https://www.readbyqxmd.com/read/28674250/prophylactic-oral-administration-of-magnesium-ameliorates-dextran-sulfate-sodium-induced-colitis-in-mice-through-a-decrease-of-colonic-accumulation-of-p2x7-receptor-expressing-mast-cells
#11
Kenshi Ohbori, Makiko Fujiwara, Akihiro Ohishi, Kentaro Nishida, Yoshinobu Uozumi, Kazuki Nagasawa
The number of patients with colitis has been increasing year by year. Recently, intestinal inflammation, as one of the factors for its onset, has been demonstrated to be induced by P2X7 receptor-mediated activation of colonic immune cells such as mast cells. Activation of P2X7 receptor (P2X7R) is known to be inhibited by divalent metal cations such as magnesium, but whether or not magnesium administration prevents/relieves colitis is unknown so far. Here, we report that oral (per os (p.o.)) administration of MgCl2 and ingestion of commercially available magnesium-rich mineral hard water relieves dextran sulfate sodium (DSS)-induced colitis in mice...
2017: Biological & Pharmaceutical Bulletin
https://www.readbyqxmd.com/read/28670718/ketamine-infusion-combined-with-magnesium-as-a-therapy-for-intractable-chronic-cluster-headache-report-of-two-cases
#12
Xavier Moisset, Pierre Clavelou, Michel Lauxerois, Radhouane Dallel, Pascale Picard
BACKGROUND: Chronic cluster headache (CH) is a rare, highly disabling primary headache condition. As NMDA receptors are possibly overactive in CH, NMDA receptor antagonists, such as ketamine, could be of interest in patients with intractable CH. CASE REPORTS: Two Caucasian males, 28 and 45 years-old, with chronic intractable CH, received a single ketamine infusion (0.5 mg/kg over 2 h) combined with magnesium sulfate (3000 mg over 30 min) in an outpatient setting...
July 3, 2017: Headache
https://www.readbyqxmd.com/read/28667642/optimization-of-nutritional-components-of-medium-by-response-surface-methodology-for-enhanced-production-of-lactase
#13
T C Venkateswarulu, K Vidya Prabhakar, R Bharath Kumar
Lactase has excellent applications in dairy industry and commercially this enzyme is produced from bacterial sources but not in high yields. In this work, the production of lactase was improved by designing of nutrient components in fermentation medium by one factor at a time. Lactose and yeast extract were selected as preferable carbon and nitrogen sources for lactase production with tryptophan and MgSO4 showing enhanced production. Statistical analysis proved to be a useful and powerful tool in developing optimum fermentation conditions...
July 2017: 3 Biotech
https://www.readbyqxmd.com/read/28667191/providing-active-antenatal-care-depends-on-the-place-of-birth-for-extremely-preterm-births-the-epipage-2-cohort-study
#14
Caroline Diguisto, François Goffinet, Elsa Lorthe, Gilles Kayem, Jean-Christophe Roze, Pascal Boileau, Babak Khoshnood, Valérie Benhammou, Bruno Langer, Loic Sentilhes, Damien Subtil, Elie Azria, Monique Kaminski, Pierre-Yves Ancel, Laurence Foix-L'Hélias
Survival rates of infants born before 25 weeks of gestation are low in France and have not improved over the past decade. Active perinatal care increases these infants' likelihood of survival. OBJECTIVE: Our aim was to identify factors associated with active antenatal care, which is the first step of proactive perinatal care in extremely preterm births. METHODS: The population included 1020 singleton births between 22(0/6) and 26(0/6) weeks of gestation enrolled in the Etude Epidémiologique sur les Petits Ages Gestationnels 2 study, a French national population-based cohort of very preterm infants born in 2011...
June 30, 2017: Archives of Disease in Childhood. Fetal and Neonatal Edition
https://www.readbyqxmd.com/read/28663608/comparison-of-usefulness-of-ketamine-and-magnesium-sulfate-nebulizations-for-attenuating-postoperative-sore-throat-hoarseness-of-voice-and-cough
#15
Sunil Rajan, George Jacob Malayil, Rekha Varghese, Lakshmi Kumar
CONTEXT: Postoperative sore throat (POST) is a complication that is unresolved in patients undergoing endotracheal intubation. AIM: To compare the effects of ketamine and magnesium sulfate nebulizations in two strengths, on the incidence and severity of POST, hoarseness, and cough. SETTINGS AND DESIGN: Sixty surgical patients undergoing elective abdominal and lower limb surgeries under combined epidural and general anesthesia were included in this prospective, randomized, double-blinded study...
April 2017: Anesthesia, Essays and Researches
https://www.readbyqxmd.com/read/28657310/a-coarse-grained-force-field-parameterized-for-mgcl2-and-cacl2-aqueous-solutions
#16
Zheng Gong, Huai Sun
Calcium and magnesium ions play important roles in many physicochemical processes. To facilitate the investigation of phenomena related to these ions that occur over large length and time scales, a coarse-grained force field (CGFF) is developed for MgCl2 and CaCl2 aqueous solutions. The ions are modeled by CG beads with characteristics of hydration shells. To accurately describe the nonideal behavior of the solutions, osmotic coefficients in a wide range of concentrations were used as guidance for parametrization...
July 12, 2017: Journal of Chemical Information and Modeling
https://www.readbyqxmd.com/read/28647239/fluoride-removal-by-al-ti-and-fe-hydroxides-and-coexisting-ion-effect
#17
Jianfeng Zhang, Timothy E Brutus, Jiemin Cheng, Xiaoguang Meng
Batch experiments were conducted to evaluate fluoride removal by Al, Fe, and Ti-based coagulants and adsorbents, as well as the effects of coexisting ions and formation of aluminum-fluoride complexes on fluoride removal by co-precipitation with alum (Al2(SO4)3·18H2O). Aluminum sulfate was more efficient than the other coagulants for fluoride removal in the pH range between 6 and 8. Nano-crystalline TiO2 was more effective for fluoride removal than Al and Fe hydroxides in a pH range of 3-5. Coexisting anions in water decreased the removal of fluoride in the order: phosphate (2...
July 2017: Journal of Environmental Sciences (China)
https://www.readbyqxmd.com/read/28642473/predicting-effects-on-oxaliplatin-clearance-in-vitro-kinetic-and-clinical-studies-of-calcium-and-magnesium-mediated-oxaliplatin-degradation
#18
Catherine H Han, Prashannata Khwaounjoo, Andrew G Hill, Gordon M Miskelly, Mark J McKeage
This study evaluated the impact of calcium and magnesium on the in vitro degradation and in vivo clearance of oxaliplatin. Intact oxaliplatin and Pt(DACH)Cl2 were measured in incubation solutions by HPLC-UV. A clinical study determined changes in plasma concentrations of calcium and magnesium in cancer patients and their impact on oxaliplatin clearance. Kinetic analyses modelled oxaliplatin degradation reactions in vitro and contributions to oxaliplatin clearance in vivo. Calcium and magnesium accelerated oxaliplatin degradation to Pt(DACH)Cl2 in chloride-containing solutions in vitro...
June 22, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28633512/media-optimization-for-economic-succinic-acid-production-by-enterobacter-sp-lu1
#19
Marcin Podleśny, Agnieszka Kubik-Komar, Jagoda Kucharska, Jakub Wyrostek, Piotr Jarocki, Zdzisław Targoński
Enterobacter sp. LU1 could efficiently convert glycerol to succinic acid under anaerobic conditions after the addition of lactose. In this study, media constituents affecting both Enterobacter sp. LU1 biomass and succinic acid production were investigated employing response surface methodology (RSM) with central composite design. Statistical methods led to the development of an efficient and inexpensive microbiological media based on crude glycerol, whey permeate as carbon sources and urea as a nitrogen source...
December 2017: AMB Express
https://www.readbyqxmd.com/read/28631456/comparison-between-adenosine-and-magnesium-sulphate-as-adjuvants-for-transversus-abdominis-plane-block-a-prospective-randomized-controlled-trial
#20
Amany S Ammar, Khaled M Mahmoud, Zeinab A Kasemy
BACKGROUND: Various adjuvants have been employed during different nerve blocks. We aimed to evaluate the effect of adding adenosine versus magnesium sulfate to bupivacaine on the quality and duration of transversus abdominis plane (TAP) block. METHODS: Participants were randomized to TAP block using either 20 ml of bupivacaine hydrochloride 0.375% + 12 mg adenosine in 2 ml of saline 0.9% (adenosine group), 20 ml of bupivacaine hydrochloride 0.375% + 500 mg magnesium sulphate in 2 ml saline 0...
June 14, 2017: Minerva Anestesiologica
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