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https://www.readbyqxmd.com/read/28068924/de-implementation-strategy-to-reduce-the-inappropriate-use-of-urinary-and-intravenous-catheters-study-protocol-for-the-ricat-study
#1
Bart J Laan, Ingrid J B Spijkerman, Mieke H Godfried, Berend C Pasmooij, Jolanda M Maaskant, Marjon J Borgert, Brent C Opmeer, Margreet C Vos, Suzanne E Geerlings
BACKGROUND: Urinary and (peripheral and central) intravenous catheters are widely used in hospitalized patients. However, up to 56% of the catheters do not have an appropriate indication and some serious complications with the use of these catheters can occur. The main objective of our quality improvement project is to reduce the use of catheters without an appropriate indication by 25-50%, and to evaluate the affecting factors of our de-implementation strategy. METHODS: In a multicenter, prospective interrupted time series analysis, several interventions to avoid inappropriate use of catheters will be conducted in seven hospitals in the Netherlands...
January 10, 2017: BMC Infectious Diseases
https://www.readbyqxmd.com/read/28058091/making-mental-health-a-global-priority
#2
Patricio V Marquez, Shekhar Saxena
At a conference in April in Washington, D.C., the World Bank Group (WBG), together with the World Health Organization (WHO) and other partners kick-started a call to action to governments, international partners, health professionals, and others to find solutions to a rising global mental health problem. Our authors write that mental disorders account for 30 percent of the non-fatal disease burden worldwide and 10 percent of overall disease burden, including death and disability, and that the global cost-estimated to be approximately $2...
July 2016: Cerebrum: the Dana Forum on Brain Science
https://www.readbyqxmd.com/read/28056179/descriptive-characteristics-of-concussions-in-national-football-league-games-2010-2011-to-2013-2014
#3
Michael D Clark, Breton M Asken, Stephen W Marshall, Kevin M Guskiewicz
BACKGROUND: Despite a high reported incidence rate of concussion, little is known about the on-field characteristics of injurious head impacts in National Football League (NFL) games. PURPOSE: To characterize on-field features (location, player position, and time during game) and biomechanical features (anticipation status, closing distance, impact location and type) associated with concussions in NFL games over a 4-season period (2010-2011 to 2013-2014). STUDY DESIGN: Descriptive epidemiology study...
December 1, 2017: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/28054492/match-running-performance-and-skill-execution-improves-with-age-but-not-the-number-of-disposals-in-young-australian-footballers
#4
Paul B Gastin, Christie Tangalos, Lorena Torres, Sam Robertson
This study investigated age-related differences in maturity, physical and functional characteristics and playing performance in youth Australian Football (AF). Young male players (n = 156) were recruited from 12 teams across 6 age groups (U10-U15) of a recreational AF club. All players were tested for body size, maturity and fitness. Player performance was assessed during a match in which disposals (kicks and handballs) and their effectiveness were coded from a video recording and match running performance measured using Global Positioning System...
January 5, 2017: Journal of Sports Sciences
https://www.readbyqxmd.com/read/28048366/su-f-t-632-on-the-use-of-intensity-modulated-arc-therapy-for-thoracic-vertebral-metastases-sbrt-treatment
#5
D Pokhrel, M Mallory, R Badkul, H Jiang, H Saleh, F Wang, C Lominska
PURPOSE: To retrospectively evaluate quality, efficiency and delivery accuracy of intensity modulated arc therapy (IMAT) plans for thoracic-vertebral metastases using stereotactic body radiotherapy (SBRT). METHODS: After obtaining approval of RPC-benchmark plan, seven previously treated thoracic-vertebral metastases patients with non-coplanar hybrid arcs(NC-HA)using 1-2 3D-dynamic conformal partial-arcs plus 7-9 IMRT-beams were re-optimized with IMAT using 3 full co-planar arcs...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28047730/su-d-bra-02-motion-assessment-during-open-face-mask-srs-using-cbct-and-surface-monitoring
#6
B B Williams, C J Fox, A C Hartford, D J Gladstone
PURPOSE: To assess the robustness of immobilization using open-face mask technology for linac-based stereotactic radiosurgery (SRS) with multiple non-coplanar arcs via repeated CBCT acquisition, with comparison to contemporaneous optical surface tracking data. METHODS: 25 patients were treated in open faced masks with cranial SRS using 3-4 non-coplanar arcs. Repeated CBCT imaging was performed to verify the maintenance of proper patient positioning during treatment...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28047649/su-g-jep1-04-characterization-of-a-high-definition-optical-patient-surface-tracking-system-across-five-installations
#7
T Smith, A Ayan, E Cochran, J Woollard, N Gupta
PURPOSE: To assess the performance of Varian's real-time, Optical Surface Monitoring System (OSMS) by measuring relative regular and irregular surface detection accuracy in 6 degrees of motion (6DoM), across multiple installations. METHODS: Varian's Intracranial SRS Package includes OSMS, which utilizes 3 HD camera/projector pods to map a patient surface, track intra-fraction motion, and gate the treatment beam if motion exceeds a threshold. To evaluate motion-detection accuracy of OSMS, we recorded shifts of a cube-shaped phantom on a single Varian TrueBeam linear accelerator as known displacements were performed incrementally across 6DoM...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28025222/mechanisms-underlying-the-nonconsumptive-effects-of-parasitoid-wasps-on-aphids
#8
K S Ingerslew, D L Finke
Natural enemies need not consume herbivores to suppress herbivore populations. Behavioral interactions can adversely impact herbivore fitness from reduced time feeding, investment in defense, or injury from failed attacks. The importance of such "nonconsumptive effects" for herbivore suppression may vary across species based on the specificity and intensity of the herbivore defensive response. In a series of manipulative studies, we quantified the nature and consequences of nonconsumptive interactions between two parasitoid wasps, Aphidius ervi Haliday and Aphidius colemani Viereck, on two aphid species, pea aphids (Acyrthosiphon pisum (Harris)) and green peach aphids (Myzus persicae (Sulzer))...
December 26, 2016: Environmental Entomology
https://www.readbyqxmd.com/read/27994765/discovery-of-highly-potent-liver-x-receptor-%C3%AE-agonists
#9
Ellen K Kick, Brett B Busch, Richard Martin, William C Stevens, Venkataiah Bollu, Yinong Xie, Brant C Boren, Michael C Nyman, Max H Nanao, Lam Nguyen, Artur Plonowski, Ira G Schulman, Grace Yan, Huiping Zhang, Xiaoping Hou, Meriah N Valente, Rangaraj Narayanan, Kamelia Behnia, A David Rodrigues, Barry Brock, James Smalley, Glenn H Cantor, John Lupisella, Paul Sleph, Denise Grimm, Jacek Ostrowski, Ruth R Wexler, Todd Kirchgessner, Raju Mohan
Introducing a uniquely substituted phenyl sulfone into a series of biphenyl imidazole liver X receptor (LXR) agonists afforded a dramatic potency improvement for induction of ATP binding cassette transporters, ABCA1 and ABCG1, in human whole blood. The agonist series demonstrated robust LXRβ activity (>70%) with low partial LXRα agonist activity (<25%) in cell assays, providing a window between desired blood cell ABCG1 gene induction in cynomolgus monkeys and modest elevation of plasma triglycerides for agonist 15...
December 8, 2016: ACS Medicinal Chemistry Letters
https://www.readbyqxmd.com/read/27993366/kicking-the-habit-of-routine-preoperative-laboratory-testing-in-children-undergoing-cardiac-surgery
#10
EDITORIAL
Andrew J Lodge
No abstract text is available yet for this article.
November 12, 2016: Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/27991485/construct-validity-of-tests-that-measure-kick-performance-for-young-soccer-players-based-on-cluster-analysis-exploring-the-relationship-between-coaches-rating-and-actual-measures
#11
Luiz H P Vieira, Vitor L DE Andrade, Rodrigo L Aquino, Renato Moraes, Fabio A Barbieri, Sérgio A Cunha, Bruno L Bedo, Paulo R Santiago
BACKGROUND: The main aim of this study was to verify the relationship between the classification of coaches and actual performance in field tests that measure the kicking performance in young soccer players, using the K--means clustering technique. METHODS: Twenty--three U--14 players performed eight tests to measure their kicking performance. Four experienced coaches provided a rating for each player as follows: 1--poor, 2--below average, 3--average, 4--very good, 5-excellent as related to three parameters (i...
December 16, 2016: Journal of Sports Medicine and Physical Fitness
https://www.readbyqxmd.com/read/27990225/quantifying-inter-segmental-coordination-during-the-instep-soccer-kicks
#12
Yumeng Li, Marion Alexander, Cheryl Glazebrook, Jeff Leiter
In order to generate a high ball speed in soccer, the inter-segmental coordination of the kicking leg is critical. The purpose of this study was to quantify the coordination between the thigh and shank movement in the sagittal plane during instep kicks. Eleven female soccer players were video recorded using a high-speed (80 Hz) video camera during penalty kicks. Hip, knee and ankle joint centers of the right leg were digitized, and the movement was analyzed using Dartfish TeamPro (6.0). The thigh and shank segment angles were generated, and the coordination was quantified using the cross-correlation and the vector coding method...
2016: International Journal of Exercise Science
https://www.readbyqxmd.com/read/27975277/cell-cycle-remodeling-and-zygotic-gene-activation-at-the-midblastula-transition
#13
Maomao Zhang, Jennifer Skirkanich, Michael A Lampson, Peter S Klein
Following fertilization, vertebrate embryos delay large-scale activation of the zygotic genome from several hours in fish and amphibians to several days in mammals. Externally developing embryos also undergo synchronous and extraordinarily rapid cell divisions that are accelerated by promiscuous licensing of DNA replication origins, absence of gap phases and cell cycle checkpoints, and preloading of the egg with maternal RNAs and proteins needed to drive early development. After a species-specific number of cell divisions, the cell cycle slows and becomes asynchronous, gap phases appear, checkpoint functions are acquired, and large-scale zygotic gene activation begins...
2017: Advances in Experimental Medicine and Biology
https://www.readbyqxmd.com/read/27975201/health-assessment-using-aqua-quality-indicators-of-alpine-streams-khunjerab-national-park-gilgit-pakistan
#14
Salar Ali, Junfeng Gao, Farida Begum, Atta Rasool, Muhammad Ismail, Yongjiu Cai, Shaukat Ali, Shujaat Ali
This preliminary research was conducted to evaluate the alpine stream health by using water quality as an indicator in Khunjerab National park of the Karakoram ranges located in Pak-China boarder Pakistan having altitude of 3660 m. This study investigated the stream health in the context of the presence or absence of sensitive species, their diversity, and their taxa richness. The water and macroinvertebrate samples were collected from 17 different locations from upstream and downstream of the river by using random sampling method...
December 14, 2016: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/27967275/velocity-oxygen-uptake-and-metabolic-cost-of-pull-kick-and-whole-body-swimming
#15
Kirstin S Morris, Mark A Osborne, Megan E Shephard, David G Jenkins, Tina L Skinner
PURPOSE: The contributions of the limbs to velocity and metabolic parameters in front-crawl swimming at different intensities have not been identified with the consideration of both stroke and kick rate. Consequently, velocity, oxygen uptake (V̇O2) and metabolic cost of swimming with the whole body (swim), the upper-limbs only (pull) and lower-limbs only (kick) were compared with stroke and kick rate controlled. METHODS: Twenty elite swimmers completed six 200m trials; two swim, two pull and two kick...
December 14, 2016: International Journal of Sports Physiology and Performance
https://www.readbyqxmd.com/read/27967045/thermodynamic-geometry-of-minimum-dissipation-driven-barrier-crossing
#16
David A Sivak, Gavin E Crooks
We explore the thermodynamic geometry of a simple system that models the bistable dynamics of nucleic acid hairpins in single molecule force-extension experiments. Near equilibrium, optimal (minimum-dissipation) driving protocols are governed by a generalized linear response friction coefficient. Our analysis demonstrates that the friction coefficient of the driving protocols is sharply peaked at the interface between metastable regions, which leads to minimum-dissipation protocols that drive rapidly within a metastable basin, but then linger longest at the interface, giving thermal fluctuations maximal time to kick the system over the barrier...
November 2016: Physical Review. E
https://www.readbyqxmd.com/read/27959272/fetal-syndrome-of-endocannabinoid-deficiency-fsecd-in-maternal-obesity
#17
Natalia Schlabritz-Loutsevitch, Nadezhda German, Gary Ventolini, Eneko Larumbe, Jacques Samson
The theory of a fetal origin of adult diseases links many pathological conditions to very early life events and is known as a "developmental programming" phenomenon. The mechanisms of this phenomenon are not quite understood and have been explained by inflammation, stress, etc. In particular the epidemic of obesity, with more than 64% of women being overweight or obese, has been associated with conditions in later life such as mental disorders, diabetes, asthma, and irritable bowel syndrome. Interestingly, these diseases were classified a decade ago as Clinical Syndrome of Endocannabinoid Deficiency (CECD), which was first described by Russo in 2004...
November 2016: Medical Hypotheses
https://www.readbyqxmd.com/read/27958591/bringing-short-lived-dissipative-kerr-soliton-states-in-microresonators-into-a-steady-state
#18
Victor Brasch, Michael Geiselmann, Martin H P Pfeiffer, Tobias J Kippenberg
Dissipative Kerr solitons have recently been generated in optical microresonators, enabling ultrashort optical pulses at microwave repetition rates, that constitute coherent and numerically predictable Kerr frequency combs. However, the seeding and excitation of the temporal solitons is associated with changes in the intracavity power that can lead to large thermal resonance shifts and render the soliton states in most commonly used resonator platforms short lived. Here we describe a "power kicking" method to overcome this instability by modulating the power of the pump laser...
December 12, 2016: Optics Express
https://www.readbyqxmd.com/read/27938874/rationale-study-protocol-and-the-cluster-randomization-process-in-a-controlled-trial-including-40-000-women-investigating-the-effects-of-mindfetalness
#19
Ingela Rådestad, Anna Akselsson, Susanne Georgsson, Helena Lindgren, Karin Pettersson, Gunnar Steineck
BACKGROUND: Shortening pre-hospital delay may decrease stillbirth rates and rates of babies born with a compromised health. Stillbirth may be preceded by a decrease in fetal movements. Mindfetalness has been developed as a response to the shortcomings of kick-counting for the monitoring of fetal movements by the pregnant woman. We do not know if practicing Mindfetalness may diminish pre-hospital delay. Nor do we know if practicing Mindfetalness may increase or decrease the percentage of women seeking health care for unfounded, from a medical perspective, worry for her fetus' well-being...
December 2016: Sexual & Reproductive Healthcare: Official Journal of the Swedish Association of Midwives
https://www.readbyqxmd.com/read/27938368/psychiatrists-experiences-of-suicide-assessment
#20
Margda Waern, Niclas Kaiser, Ellinor Salander Renberg
BACKGROUND: Clinical guidelines for suicide prevention often stress the identification of risk and protective factors as well as the evaluation of suicidal intent. However, we know very little about what psychiatrists actually do when they make these assessments. The aim was to investigate psychiatrists' own accounts of suicide assessment consultations, with a focus on their behaviors, attitudes and emotions. METHOD: Semi-structured in depth interviews were carried out with a purposive selection of 15 psychiatrists...
December 9, 2016: BMC Psychiatry
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