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https://www.readbyqxmd.com/read/28444408/prolapse-assessment-supine-and-standing-do-we-need-different-cutoffs-for-significant-prolapse
#1
Nuria-Laia Rodríguez-Mias, Nishamini Subramaniam, Talia Friedman, Ka Lai Shek, Hans Peter Dietz
INTRODUCTION AND HYPOTHESIS: Translabial ultrasound (TLUS) has shown good correlations between clinical examination and imaging findings in the supine position, and limits of normality have been described. This is not the case for imaging in the standing position. This study was designed to test the hypothesis that different cutoff values are required for imaging in the standing position. METHODS: This was a retrospective study carried out in a tertiary urogynecological unit in women presenting with symptoms of lower urinary tract and pelvic floor dysfunction between August 2013 and December 2015...
April 25, 2017: International Urogynecology Journal
https://www.readbyqxmd.com/read/28442384/the-optimal-settings-for-non-contact-holmium-yag-stone-fragmentation-pop-corn-technique
#2
Esteban Emiliani, Michele Talso, Sung-Yong Cho, Mohammed Baghdadi, Sadam Ghanem, Hugo Pinheiro, Olivier Traxer
PURPOSE: The purpose of this study was to evaluate the "pop-corn" technique with a wide range of holmium laser settings and fiber sizes in a systematic in-vitro assessment. MATERIALS AND METHODS: The evaluations were done with 4 artificial stones in a Vacutaner. A fixed ureteroscope was inserted through a ureteral access sheath providing constant irrigation flow and the laser was placed 1 mm from the bottom. Combinations of 0.5-1.5 Joules, 10-20 and 40Hz, and long and short pulses were tested for 2 and 4 minutes...
April 22, 2017: Journal of Urology
https://www.readbyqxmd.com/read/28442012/-preoperatiove-airway-bacterial-colonization-the-missing-link-between-non-small-cell-lung-cancer-following-lobectomy-and-postoperative-pneumonia
#3
Ke Gao, Yutian Lai, Jian Huang, Yifan Wang, Xiaowei Wang, Guowei Che
BACKGROUND: Surgical procedure is the main method of treating lung cancer. Meanwhile, postoperative pneumonia (POP) is the major cause of perioperative mortality in lung cancer surgery. The preoperative pathogenic airway bacterial colonization is an independent risk factor causing postoperative pulmonary complications (PPC). This cross-sectional study aimed to explore the relationship between preoperative pathogenic airway bacterial colonization and POP in lung cancer and to identify the high-risk factors of preoperative pathogenic airway bacterial colonization...
April 20, 2017: Zhongguo Fei Ai za Zhi, Chinese Journal of Lung Cancer
https://www.readbyqxmd.com/read/28441596/individual-variation-of-persistent-organic-pollutants-in-relation-to-stable-isotope-ratios-sex-reproductive-phase-and-oxidative-status-in-scopoli-s-shearwaters-calonectris-diomedea-from-the-southern-mediterranean
#4
David Costantini, Manrico Sebastiano, Martina S Müller, Igor Eulaers, Per Ambus, Govindan Malarvannan, Adrian Covaci, Bruno Massa, Giacomo Dell'Omo
Little is known about the accumulation of persistent organic pollutants (POPs) and its consequences for seabirds in the Mediterranean basin. We characterised the plasma contaminant profile (polychlorinated biphenyls ΣPCBs; organochlorine pesticides ΣOCPs; polybrominated diphenyl ethers ΣPBDEs) of a population of the seabird Scopoli's shearwater (Calonectris diomedea) that breeds in the southern Mediterranean (Linosa Island) and investigated (i) whether sex, stable isotope ratios (related to diet), reproductive phase (early incubation vs...
April 22, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28440937/microplastics-are-not-important-for-the-cycling-and-bioaccumulation-of-organic-pollutants-in-the-oceans-but-should-microplastics-be-considered-pops-themselves
#5
Rainer Lohmann
The role of microplastic particles in the cycling and bioaccumulation of persistent organic pollutants (POPs) is discussed. Five common concepts, sometimes misconceptions, about the role of microplastics are reviewed. While there is ample evidence that microplastics accumulate high concentrations of POPs, this does not result in microplastics being important for the global dispersion of POPs. Similarly, there is scant evidence that microplastics are an important transfer vector of POPs into animals, but possibly for plastic additives (flame retardants)...
May 2017: Integrated Environmental Assessment and Management
https://www.readbyqxmd.com/read/28440643/field-calibration-of-xad-based-passive-air-sampler-on-the-tibetan-plateau-wind-influence-and-configuration-improvement
#6
Ping Gong, Xiao-Ping Wang, Xiande Liu, Frank Wania
The passive air sampler based on XAD-2 resin (XAD-PAS) has proven useful for collecting atmospheric persistent organic pollutants (POPs) in remote regions. Whereas laboratory studies have shown that, due to the open bottom of its housing, the passive sampling rate (PSR) of the XAD-PAS is susceptible to wind and other processes causing air turbulence, the sampler has not been calibrated in the field at sites experiencing high winds. In this study, the PSRs of the XAD-PAS were calibrated at three sites on the Tibetan Plateau, covering a wide range in temperature (T), pressure (P) and wind speed (v)...
April 25, 2017: Environmental Science & Technology
https://www.readbyqxmd.com/read/28438788/associations-between-persistent-organic-pollutants-type-2-diabetes-diabetic-nephropathy-and-mortality
#7
Brian A Grice, Robert G Nelson, Desmond E Williams, William C Knowler, Clinton Mason, Robert L Hanson, Kai McKeever Bullard, Meda E Pavkov
OBJECTIVE: Relationships were examined between persistent organic pollutants (POPs) and incident type 2 diabetes, end-stage renal disease (ESRD) and mortality. METHODS: In a nested case-control study, 300 persons without diabetes had baseline examinations between 1969 and 1974; 149 developed diabetes (cases) and 151 remained non-diabetic (controls) during 8.0 and 23.1 years of follow-up, respectively. POPs were measured at baseline. ORs for diabetes were computed by logistic regression analysis...
April 24, 2017: Occupational and Environmental Medicine
https://www.readbyqxmd.com/read/28437774/bacterial-community-dynamics-and-functional-variation-during-the-long-term-decomposition-of-cyanobacterial-blooms-in-vitro
#8
Limei Shi, Yaxin Huang, Min Zhang, Yang Yu, Yaping Lu, Fanxiang Kong
Cyanobacterial blooms drastically influence carbon and nutrient cycling in eutrophic freshwater lakes. To understand the mineralization process of cyanobacteria-derived particulate organic matter (CyanPOM), the aerobic degradation of cyanobacterial blooms dominated by Microcystis sp. was investigated over a 95-day microcosm experiment. Approximately 91%, 95% and 83% of the initial particulate organic carbon (POC), particulate organic nitrogen (PON), and particulate organic phosphorus (POP) were decomposed, respectively...
April 21, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28432626/temporal-trends-of-lipophilic-persistent-organic-pollutants-in-serum-from-danish-nulliparous-pregnant-women-2011-2013
#9
Christian Bjerregaard-Olesen, Manhai Long, Mandana Ghisari, Bodil H Bech, Ellen A Nohr, Niels Uldbjerg, Tine B Henriksen, Jørn Olsen, Eva C Bonefeld-Jørgensen
The use of the lipophilic persistent organic pollutants (POPs) including polychlorinated biphenyls (PCBs) and several organochlorine pesticides (OCPs) has been prohibited for more than 30 years. In this study, we present the temporal trends of the lipophilic POP serum concentrations in Danish nulliparous pregnant women between 2011 and 2013. We randomly selected 197 pregnant women (gestational age 11-13) from the Aarhus Birth Cohort. The concentrations of the lipophilic POPs in the serum samples were analyzed using gas chromatography...
April 21, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/28431536/-popping-nana-back-into-bed-a-qualitative-exploration-of-paramedic-decision-making-when-caring-for-older-people-who-have-fallen
#10
Paul Simpson, Ric Thomas, Jason Bendall, Bill Lord, Stephen Lord, Jacqueline Close
BACKGROUND: Older fallers constitute a large proportion of ambulance work, and as many as 25% are not transported to hospital following paramedic assessment. The objective of this study was to explore the decision making process used by paramedics when caring for older fallers. METHODS: A qualitative study was conducted using constructivist grounded theory methodology. Purposive sampling was used to recruit paramedics to participate in semi-structured interviews and focus groups...
April 21, 2017: BMC Health Services Research
https://www.readbyqxmd.com/read/28431204/factors-that-affect-outcomes-of-prolapse-repair-using-single-incision-vaginal-mesh-procedures
#11
Hsiao-Yun Hsieh, Ching-Pei Tsai, Chih-Ku Liu, Pao-Sheng Shen, Yao-Ching Hung, Man-Jung Hung
AIMS: Single-incision vaginal mesh (SIVM) procedures for pelvic organ prolapse (POP) differed in mesh fabrication and implantation that may affect treatment outcomes. We aim to evaluate and compare the safety and effectiveness of two SIVM procedures, and explore factors that may have associations with surgical effectiveness. METHODS: Our data of using two SIVM procedures for a total (anterior and posterior) vaginal mesh repair were studied. Patients who had ≧stage 2 POP and underwent either Elevate (n = 85) using anchored, lightweight meshes or Prosima procedures (n = 95) using non-anchored, original meshes were assessed...
April 21, 2017: Neurourology and Urodynamics
https://www.readbyqxmd.com/read/28430939/visualizing-induced-silent-steam-pop-with-intracardiac-echocardiography
#12
Yusuke Kondo, Marehiko Ueda, Yoshio Kobayashi
No abstract text is available yet for this article.
April 18, 2017: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
https://www.readbyqxmd.com/read/28424020/the-utility-of-an-obesity-specific-small-for-gestational-age-standard-for-pregnancies-complicated-by-maternal-obesity
#13
Ruofan Yao, Sarah E Foster, Aaron B Caughey
INTRODUCTION: An obesity-specific standard for small for gestational age (SGA) pregnancies may help identify additional at risk pregnancies. METHODS: This was a retrospective cohort study of all non-anomalous singleton neonates born in Texas from 2006-2011. Analysis was limited to births between 34 and 42 weeks gestation. Two SGA birth weight standards (birth weight ≤ 10(th) centile) were generated, one using the entire population (SGApop) and another using obese pregnancies (SGAcust)...
April 19, 2017: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/28420543/serum-persistent-organic-pollutants-pops-and-prostate-cancer-risk-a-case-cohort-study
#14
Jung-Eun Lim, Chungmo Nam, Jiyeon Yang, Koon Ho Rha, Kyung-Min Lim, Sun Ha Jee
It is still unclear whether persistent organic pollutants (POPs) exposure increases the prostate cancer incidence risk. This prospective cohort study evaluated the associations between serum POPs concentrations and prostate cancer risk. Within a case-cohort study, we identified 110 people diagnosed with prostate cancer and randomly selected 256 sub-cohort participants without prostate cancer. Serum concentrations of 32 polychlorinated biphenyl (PCB) congeners and 19 organochlorine pesticides (OCPs) were measured...
April 10, 2017: International Journal of Hygiene and Environmental Health
https://www.readbyqxmd.com/read/28419885/registry-of-implants-for-the-reconstruction-of-pelvic-floor-in-males-and-females-a-feasibility-case-series
#15
Dimitri Barski, Holger Gerullis, Thorsten Ecke, Jennifer Kranz, Laila Schneidewind, Nadine Leistner, Fabian Queissert, Sandra Mühlstädt, Markus Grabbert, Rana Tahbaz, Alexandre Egon Pelzer, Ralf Joukhadar, Uwe Klinge, Mihaly Boros, Werner Bader, Gert Naumann, Frank Puppe, Thomas Otto
INTRODUCTION: Most aspects of implant-assisted reconstruction of pelvic floor in males and females are under debate and the research is not standardized. Registries are supposed to shed light to the indications, surgical techniques and material properties and to establish a standardized evaluation. METHODS: A working group was formed to create an online platform for registration and outcome measurement of implant-assisted operations for pelvic organ prolapse (POP) and female and male stress urinary incontinence (SUI)...
April 15, 2017: International Journal of Surgery
https://www.readbyqxmd.com/read/28419778/single-and-multiple-dose-pharmacokinetics-of-once-daily-formulations-of-raltegravir
#16
Rajesh Krishna, Matthew L Rizk, Patrick Larson, Valerie Schulz, Filippos Kesisoglou, Radu Pop
A new once-daily formulation of raltegravir, an integrase strand transfer inhibitor indicated in combination with other antiretroviral drugs for the treatment of human immunodeficiency virus-1 infection, is under development. Single-dose and steady-state pharmacokinetics of 1200 mg for 2 formulations of raltegravir were characterized in 2 open-label phase 1 studies in healthy male and female subjects aged 18 to 55 years. The new raltegravir 600-mg formulation had a higher relative bioavailability compared with the 400-mg tablets...
April 17, 2017: Clinical Pharmacology in Drug Development
https://www.readbyqxmd.com/read/28419507/a-rapid-solvent-accessible-surface-area-estimator-for-coarse-grained-molecular-simulations
#17
Shuai Wei, Charles L Brooks, Aaron T Frank
The rapid and accurate calculation of solvent accessible surface area (SASA) is extremely useful in the energetic analysis of biomolecules. For example, SASA models can be used to estimate the transfer free energy associated with biophysical processes, and when combined with coarse-grained simulations, can be particularly useful for accounting for solvation effects within the framework of implicit solvent models. In such cases, a fast and accurate, residue-wise SASA predictor is highly desirable. Here, we develop a predictive model that estimates SASAs based on Cα-only protein structures...
June 5, 2017: Journal of Computational Chemistry
https://www.readbyqxmd.com/read/28419067/clinical-use-of-ring-with-support-pessary-for-advanced-pelvic-organ-prolapse-and-predictors-of-its-short-term-successful-use
#18
Mou Deng, Jing Ding, Fangfang Ai, Lan Zhu
OBJECTIVE: This study aimed to evaluate the success rate, patient satisfaction and adverse events with the use of the ring with support pessary in patients with advanced pelvic organ prolapse (POP), and to identify the factors associated with successful pessary use. METHODS: In this prospective study, 151 patients with symptomatic advanced POP (POP quantification stage III/IV) came to the Centre of Obstetrics and Gynaecology, Peking Union Medical College Hospital, for POP treatment between May 2015 and December 2015...
April 17, 2017: Menopause: the Journal of the North American Menopause Society
https://www.readbyqxmd.com/read/28417156/patient-satisfaction-after-laparoscopic-lateral-suspension-with-mesh-for-pelvic-organ-prolapse-outcome-report-of-a-continuous-series-of-417-patients
#19
Nikolaus Veit-Rubin, Jean-Bernard Dubuisson, Angèle Gayet-Ageron, Sören Lange, Isabelle Eperon, Jean Dubuisson
INTRODUCTION AND HYPOTHESIS: Sacropexy is considered the gold standard for the treatment of pelvic organ prolapse (POP) although dissection of the promontory may be challenging, particularly in obese women. Laparoscopic lateral suspension with mesh (LLS) could be an alternative. METHODS: LLS provides lateral attachment by fibrosis of a vesicovaginal mesh. Clinical evaluation was performed at 1 year using the simplified POP quantification system (POP-Q). Primary outcomes were objective and subjective cure at 1 year...
April 17, 2017: International Urogynecology Journal
https://www.readbyqxmd.com/read/28417155/pelvic-floor-symptoms-and-quality-of-life-changes-during-first-pregnancy-a-prospective-cohort-study
#20
Rebecca G Rogers, Cara Ninivaggio, Kelly Gallagher, A Noelle Borders, Clifford Qualls, Lawrence M Leeman
INTRODUCTION AND HYPOTHESIS: We describe pelvic floor function in nulliparous pregnant women. MATERIALS AND METHODS: Nulliparous midwifery patients completed the Incontinence Severity Index (ISI), Pelvic Floor Impact Questionnaire (PFIQ-7), Wexner Fecal Incontinence Scale (W), and answered questions about sexual activity and perineal pain at baseline during the first (T1), second (T2), or third trimester (T3) and repeated in late T3. They also underwent a Pelvic Organ Prolapse Quantification (POP-Q) exam at their baseline visit...
April 17, 2017: International Urogynecology Journal
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