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https://www.readbyqxmd.com/read/29222320/anticoagulation-with-vads-and-ecmo-walking-the-tightrope
#1
REVIEW
Leslie Raffini
The evolution of devices for mechanical circulatory support (MCS), including ventricular assist devices (VADs) for patients with heart failure and extracorporeal membrane oxygenation (ECMO) for patients with acute cardiac or respiratory failure, has improved survival for subsets of critically ill children and adults. The devices are intricate and complex, allowing blood to bypass the heart or lungs (or both). As blood flows through these artificial devices, normal hemostasis is disrupted, coagulation is promoted, and in the absence of anticoagulation, a thrombus may form in the device, resulting in device failure or embolic stroke...
December 8, 2017: Hematology—the Education Program of the American Society of Hematology
https://www.readbyqxmd.com/read/29221959/robotically-assisted-percutaneous-coronary-intervention-reasons-for-partial-manual-assistance-or-manual-conversion
#2
Jonathan Harrison, Lawrence Ang, Jesse Naghi, Omid Behnamfar, Ali Pourdjabbar, Mitul P Patel, Ryan R Reeves, Ehtisham Mahmud
BACKGROUND: Robotically-assisted percutaneous coronary intervention (R-PCI) is feasible for simple coronary lesions. OBJECTIVES: To determine the frequency and reasons for partial manual assistance or manual conversion during R-PCI in clinical practice. METHODS: The CorPath 200 System (Corindus, Waltham, MA) enables the operator to sit in a radiation-shielded cockpit and remotely control intracoronary devices including guidewires, balloons, and stents...
November 9, 2017: Cardiovascular Revascularization Medicine: Including Molecular Interventions
https://www.readbyqxmd.com/read/29221520/disability-characteristics-of-community-based-rehabilitation-participants-in-kayunga-district-uganda
#3
Lukia Namaganda Hamid, Olive Kobusingye, Sebastian Olikira Baine, Chrispus Mayora, Jacob A Bentley
BACKGROUND: Approximately 80% of individuals with disability reside in low- and middle-income countries where community-based rehabilitation (CBR) has been used as a strategy to improve disability. However, data relating to disability severity among CBR beneficiaries in low-income countries like Uganda remain scarce, particularly at the community or district level. OBJECTIVES: To describe severity of disability and associated factors for persons with physical disabilities receiving CBR services in the Kayunga district of Uganda...
May 2017: Annals of Global Health
https://www.readbyqxmd.com/read/29219945/vats-plication-of-the-diaphragm-a-descriptive-observational-10-year-southampton-experience
#4
Rhona J Taberham, Adnan Raza, Aiman Alzetani, Edwin B Woo, Martin H Chamberlain, George Koulaxouzidis, Khalid M Amer
OBJECTIVE: The aim of the study was to report the safety and efficacy of video-assisted thoracoscopic (VATS) plication of the diaphragm at our institution between 2006 and 2016. METHODS: Adult patients selected on etiology and combination of investigations including plain chest x-ray, computed tomography of chest and abdomen, lung functions in supine and sitting positions, radiological/ultrasonic screening for diaphragmatic movement, and phrenic nerve conduction studies...
December 6, 2017: Innovations: Technology and Techniques in Cardiothoracic and Vascular Surgery
https://www.readbyqxmd.com/read/29219877/effectiveness-of-robotic-assisted-rehabilitation-for-mobility-and-functional-ability-in-adult-stroke-patients-a-systematic-review
#5
Kenneth Lo, Matthew Stephenson, Craig Lockwood
BACKGROUND: Stroke is a leading cause of long-term disability, and rehabilitation, involving repetitive, high intensity, task-specific exercises, is the pathway to restoring motor skills. Robotic assistive devices are increasingly being used and it is hoped that with robotic devices, rehabilitation progress can be achieved for patients. OBJECTIVES: To examine the effectiveness of robotic devices in the rehabilitation of stroke patients for upper limb mobility, lower limb mobility, and activities of daily living...
December 2017: JBI Database of Systematic Reviews and Implementation Reports
https://www.readbyqxmd.com/read/29219008/powered-off-road-wheelchair-for-the-transportation-of-tetraplegics-along-mountain-trails
#6
Michele Gabrio Antonelli, Stefano Alleva, Pierluigi Beomonte Zobel, Francesco Durante, Terenziano Raparelli
PURPOSE: For off-road mobility, some manual or power assisted devices were conceived to be self-driven by paraplegics while for tetraplegics non power-assisted devices were conceived. These devices require one or more conductors who are subjected to a high physical demand thus potentially creating: precarious safety condition for the user an elevated physical demand of conductors could reduce the care and the attention to give to the user; the time of the outdoor adventure experience of the user could be limited...
December 8, 2017: Disability and Rehabilitation. Assistive Technology
https://www.readbyqxmd.com/read/29218755/reducing-trap-assisted-recombination-in-small-organic-molecule-based-photovoltaics-by-the-addition-of-a-conjugated-block-copolymer
#7
Kyuwan Cho, Jinseck Kim, So Yeon Yoon, Ka Yeon Ryu, Song-Rim Jang, Bogyu Lim, Kyungkon Kim
The performance of organic photovoltaics (OPVs) based on the small-molecule organic semiconductor p-DTS(FBTTh2 )2 is greatly improved by the addition of a conjugated block copolymer composed of difluoroquinoxaline and thienopyrrolodione blocks (D130). The power conversion efficiency (PCE) of the p-DTS(FBTTh2 )2 -based OPV is improved from 5.08% to 6.75% by the addition of 5 wt% D130 to the photoactive layer, which is composed of p-DTS(FBTTh2 )2 and a fullerene derivative. Current-voltage and grazing incidence wide-angle X-ray scattering analyses revealed that the addition of D130 significantly reduces the trap density of the device and changes the packing orientation of p-DTS(FBTTh2 )2 from mostly edge-on to partially face-on...
December 8, 2017: Macromolecular Rapid Communications
https://www.readbyqxmd.com/read/29218673/results-of-endoscopic-vacuum-assisted-closure-device-for-treatment-of-upper-gi-leaks
#8
Marc Bludau, Hans F Fuchs, Till Herbold, Martin K H Maus, Hakan Alakus, Felix Popp, Jessica M Leers, Christiane J Bruns, Arnulf H Hölscher, Wolfgang Schröder, Seung-Hun Chon
BACKGROUND: Esophageal perforations and postoperative leakage of esophagogastrostomies are considered to be life-threatening conditions due to the potential development of mediastinitis and consecutive sepsis. Vacuum-assisted closure (VAC) techniques, a well-established treatment method for superficial infected wounds, are based on a negative pressure applied to the wound via a vacuum-sealed sponge. Endoluminal VAC (E-VAC) therapy as a treatment for GI leakages in the rectum was introduced in 2008...
December 7, 2017: Surgical Endoscopy
https://www.readbyqxmd.com/read/29217463/electrical-storm-in-the-early-phase-of-heartmate%C3%A2-ii-device-implantation-incidence-risk-factors-and-prognosis
#9
Jerome Corre, François Picard, Rodrigue Garcia, Adlane Zemmoura, Nicolas Derval, Arnaud Denis, Antoine Romen, Karine Nubret, Pierre Jais, Michel Haissaguerre, Pierre Dos Santos, Laurent Barandon, Frederic Sacher
BACKGROUND: Ventricular arrhythmia is common after left ventricular assist device (LVAD) implantation, especially in the early postoperative phase (<30 days). AIM: To identify the incidence of and risk factors for electrical storm (ES) occurring within 30 days of HeartMate® II implantation. METHODS: We reviewed data from all consecutive patients undergoing HeartMate® II device implantation at our institution from January 2008 to December 2014...
December 4, 2017: Archives of Cardiovascular Diseases
https://www.readbyqxmd.com/read/29216771/survey-of-the-functional-priorities-in-patients-with-disability-due-to-neuromuscular-disorders
#10
Nivedita U Jerath, Kevin Simoens, Dylan Mann, Steph Kollasch, Nicole Grosland, Karim A Malik, Chandan G Reddy
TITLE: Survey of the functional priorities in patients with disability due to neuromuscular disorders. OBJECTIVE: This study attempts to determine the functional priorities for patients with neuromuscular disorders. METHODS: A survey asking about functional priorities with respect to activities of daily living, ankle foot orthotic design, and assistive device design, was distributed to patients with neuromuscular disorders to assess the needs of patients from their perspectives...
December 8, 2017: Disability and Rehabilitation. Assistive Technology
https://www.readbyqxmd.com/read/29216604/digital-holographic-microscopy-for-3d-surface-characterization-of-polymeric-nanocomposites
#11
Vahid Abbasian, Ehsan A Akhlaghi, Mohammad A Charsooghi, Maasoomeh Bazzar, Ali-Reza Moradi
The aim of this paper is to introduce digital holographic microscopy (DHM) as a non-contact, inexpensive, and non-abrasive method for 3D surface characterization of polymeric nanocomposites. A common-path and vibration-immune Mirau system with a microsphere-assisted arrangement is utilized to increase the lateral resolution of the images. The characterization is performed through the measurement of roughness parameters of the surfaces, which are derived from the recorded holograms. Pure poly(triazole-amide-imide) (PTAI) and PTAI nanocomposite reinforeced with surface modified TiO2 nanoparticles (MN-TiO2) are used and compared...
November 28, 2017: Ultramicroscopy
https://www.readbyqxmd.com/read/29216577/performance-enhancement-of-perovskite-solar-cells-by-employing-tio2-nanorod-arrays-decorated-with-cuins2-quantum-dots
#12
Feng Gao, Haitao Dai, Hongfei Pan, Yuanfang Chen, Jingkang Wang, Zhijian Chen
In this work, TiO2 nanorod arrays (TiO2-NAs) were modified by CuInS2 quantum dots (CuInS2 QDs) on the surface of the nanorods. The resultant TiO2-CuInS2 nanorod arrays (TiO2-CuInS2-NAs) were characterized by UV/Vis spectroscopy, transmission electronic microscopy (TEM), and X-ray diffraction (XRD). The TiO2-CuInS2-NAs were applied as scaffold for the preparation of organic-inorganic hybrid perovskite solar cells. In comparison with the solar cell devices based on TIO2-NAs, a significant improvement in the power conversion efficiency had been achieved and the highest efficiency was obtained as 11...
November 22, 2017: Journal of Colloid and Interface Science
https://www.readbyqxmd.com/read/29215366/implantable-cardioverter-defibrillators-and-survival-in-continuous-flow-left-ventricular-assist-device-patients
#13
Valentina Kutyifa, Genaro Fernandez, Saadia Sherazi, Mehmet Aktas, David Huang, Scott McNitt, Anna Papernov, Meng Wang, H Todd Massey, Leway Chen, Jeffrey D Alexis
The association of an implantable cardioverter defibrillator (ICD) with survival in patients with left ventricular assist devices (LVADs) is not well understood. We evaluated all-cause mortality by the presence of an ICD at the time of LVAD implantation, or by ICD implantation after LVAD placement in 191 patients, using Kaplan-Meier survival analyses and Cox models with multivariate adjustment. During the median follow-up of 23 months, 33 of 129 patients (26%) with an ICD and 17 of 62 patients (27%) without an ICD died...
December 5, 2017: ASAIO Journal: a Peer-reviewed Journal of the American Society for Artificial Internal Organs
https://www.readbyqxmd.com/read/29214945/-quality-of-life-and-mental-health-of-patients-with-severe-heart-failure-with-or-without-technical-support-for-the-left-cardiac-ventricle-a-cross-sectional-study
#14
Birte Dahrmann, Jürgen Sindermann, Thomas Geldmacher, Gereon Heuft
Quality of life and mental health of patients with severe heart failure with or without technical support for the left cardiac ventricle - a cross-sectional study Objectives: Chronic heart failure is associated with reduced quality of life (QoL) and poor prognosis. Support via a left ventricular assist device (LVAD) is an alternative to optimised medical management for patients with advanced heart failure. This study evaluated health-related QoL with both therapy options. METHODS: In this consecutive cross-sectional study, patients with LVAD support (n = 50) and patients with optimised medical management (n = 50) were interviewed comprehensively about various domains of QoL, emotional stress, perceived self-efficacy, social support, life satisfaction, and communication...
December 2017: Zeitschrift Für Psychosomatische Medizin und Psychotherapie
https://www.readbyqxmd.com/read/29214596/preparing-for-the-future-of-rare-diseases
#15
Stephen C Groft, Manuel Posada de la Paz
Members of the rare disease community have devoted significant financial and personnel resources to address the numerous issues surrounding rare diseases. The past has been devoted to developing an emphasis on rare diseases including an emphasis on research studies or locating information on rare diseases and the requirements and limitations of conducting clinical trials with small patient populations. The expanded role of patient advocacy organizations and patient engagement in all aspects of clinical research continues to gain acceptance within the research community...
2017: Advances in Experimental Medicine and Biology
https://www.readbyqxmd.com/read/29214108/reflectance-confocal-microscopy-of-an-inverted-follicular-keratosis-mimicking-a-squamous-cell-carcinoma
#16
Sarah Hocker, Harold S Rabinovitz, Margaret Oliviero, Jane Grant-Kels, Alon Scope
Distinguishing between benign and malignant neoplasms of the skin is a daily challenge to dermatologists. With the use of a dermatoscope and other imaging devices, the diagnosis is often more precise. The confocal microscope is a device that uses a near-infrared laser to perform noninvasive imaging of the skin. The benefit is that the images immediately provide additional, cellular-level information that can assist in diagnosis. However, lesions may share overlapping characteristics on confocal microscopy, and hence, benign lesions can still display confocal features concerning for a cancerous process, justifying a biopsy...
October 2017: Dermatology Practical & Conceptual
https://www.readbyqxmd.com/read/29211843/sexual-activity-in-patients-with-left-ventricular-assist-devices-and-their-partners-impact-of-the-device-on-quality-of-life-anxiety-and-depression
#17
Christiane Kugler, Michael Meng, Erik Rehn, Michiel Morshuis, Jan F Gummert, Katharina Tigges-Limmer
OBJECTIVES: Prolonged support with a left ventricular assist device (LVAD) has evolved as an alternative treatment strategy for patients with end-stage heart disease. This requires a shift in focus on sexual activity and psychosocial outcomes in patients with an LVAD and their partners. METHODS: This cross-sectional study was designed to capture Sexual Activities in Left Ventricular Assist Device Patients Or PaRtners (SALVADOR) perceptions on illness-related changes in the quality of sexual activity and its impact on quality of life, anxiety and depression using standardized patient-reported outcome scales (Sexual Adjustment Scale, 36-Item Short Form Health Survey, Hospital Anxiety and Depression Scale)...
December 2, 2017: European Journal of Cardio-thoracic Surgery
https://www.readbyqxmd.com/read/29211226/implantation-of-short-term-and-long-term-right-ventricular-assist-devices
#18
Christiano Castello Branco Caldeira, Regimar Carla Machado, Debora Castello Branco Caldeira
The last decade has seen considerable growth in the use of left ventricular assist devices (LVAD), in end-phase heart failure treatment. The indications, contraindications and implantation techniques are well-defined. However, information about mechanical support for right ventricular failure is lacking. The aim of this communication is to present alternative techniques for implantation of short- and longterm right ventricular assist devices. Implanting the device in the right atrium has certain advantages when compared with the right ventricle...
September 2017: Brazilian Journal of Cardiovascular Surgery
https://www.readbyqxmd.com/read/29210774/liberal-right-ventricular-assist-device-extracorporeal-membrane-oxygenation-support-for-right-ventricular-failure-after-implantable-left-ventricular-assist-device-placement
#19
Quentin Fischer, Matthias Kirsch
Refractory right ventricular failure (RVF) after implantation of left ventricular assist device (LVAD) is a dramatic complication. The addition of right ventricular assist device (RVAD) may improve RV recovery and lead to improve outcomes. From February 2012 to September 2014, 44 patients received a HeartMate II. These patients were retrospectively compared in two groups according to early liberal implantation of an extracorporeal membrane oxygenation (ECMO) used as a RVAD established between a femoral vein and the pulmonary artery...
November 27, 2017: ASAIO Journal: a Peer-reviewed Journal of the American Society for Artificial Internal Organs
https://www.readbyqxmd.com/read/29210773/do-psychosocial-factors-have-any-impact-on-outcomes-after-left-ventricular-assist-device-implantation
#20
Scott Lundgren, Brian D Lowes, Ronald Zolty, Adam Burdorf, Eugenia Raichlin, John Y Um, Cecilia Poon
Psychosocial factors have been show to impact survival and outcomes in a number of different diseases, including heart failure and patients receiving heart transplantation. With the increasing utilization of these devices, it is important to identify risk factors that could impact post-left ventricular assist device (LVAD) outcomes. This study was a single center, retrospective analysis of 238 patients who underwent implantation of a LVAD between July 27, 2004, and July 21, 2016, at The University of Nebraska Medical Center...
November 27, 2017: ASAIO Journal: a Peer-reviewed Journal of the American Society for Artificial Internal Organs
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