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https://www.readbyqxmd.com/read/29333580/persistent-organochlorine-contaminant-residues-in-tissues-of-hedgehogs-from-turkey
#1
Kalender Arıkan, Zeynep Yaşar Arıkan, Salih Levent Turan
The residues of persistent organochlorinated pollutants (POPs), namely polychlorinated biphenyls (PCBs) and organochlorine pesticides (OCPs) (HCHs, CHLs, HCCPs, DDTs, and dicofol congeners) were investigated in the hair and muscle of road-killed Erinaceus roumanicus and E. concolor in Turkey. Mean residue levels were as follows: in hair, PCBs = 7.43 ± 4.88 ng/g and OCPs = 9.21 ± 1.27 ng/g; in muscle, PCBs = 30.73 ± 2.51 ng/g and OCPs = 145.04 ± 16.59 ng/g. There was no significant difference between species and sex, while there was significant difference between habitats and regions in terms of either total PCB and OCP levels, or POP levels (p < 0...
January 15, 2018: Bulletin of Environmental Contamination and Toxicology
https://www.readbyqxmd.com/read/29332276/variability-and-reliability-of-pop-concentrations-in-multiple-breast-milk-samples-collected-from-the-same-mothers
#2
Risa Kakimoto, Masayoshi Ichiba, Akiko Matsumoto, Kunihiko Nakai, Nozomi Tatsuta, Miyuki Iwai-Shimada, Momoko Ishiyama, Noriko Ryuda, Takashi Someya, Ieyasu Tokumoto, Daisuke Ueno
Risk assessment of infant using a realistic persistent organic pollutant (POP) exposure through breast milk is essential to devise future regulation of POPs. However, recent investigations have demonstrated that POP levels in breast milk collected from the same mother showed a wide range of variation daily and monthly. To estimate the appropriate sample size of breast milk from the same mother to obtain reliable POP concentrations, breast milk samples were collected from five mothers living in Japan from 2006 to 2012...
January 13, 2018: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/29332252/a-review-of-the-impact-of-pregnancy-and-childbirth-on-pelvic-floor-function-as-assessed-by-objective-measurement-techniques
#3
REVIEW
Hans Van Geelen, Donald Ostergard, Peter Sand
The objective of this narrative review is to study the impact of pregnancy and childbirth on pelvic floor function as assessed by objective measurement techniques with quantitative data carried out during pregnancy and after childbirth. A literature search in MEDLINE and relevant and up-to-date journals from 1960 until April 2017 was performed for articles dealing with the impact of pregnancy and childbirth on pelvic floor function as assessed by objective measurement methods. Only studies describing objective measurement techniques...
January 13, 2018: International Urogynecology Journal
https://www.readbyqxmd.com/read/29331773/impact-of-co-exposure-of-aldrin-and-titanium-dioxide-nanoparticles-at-biochemical-and-molecular-levels-in-zebrafish
#4
Reena C Jhamtani, Saurabh Shukla, P Sivaperumal, M S Dahiya, Rakhi Agarwal
Aldrin (ALD), a persistent-organic-pollutant (POP), an organochlorine-cyclodiene-pesticide is highly toxic in nature. Titanium dioxide nanoparticles (TNP) are widely used for various industrial applications. Despite the remarkable research on pesticide toxicity, the work with impact of nanoparticles on POP has been dealt with marginally. Chemicals co-exist in the environment and exhibit interactive effects. An investigation was carried out to evaluate the individual and combined effects of ALD (6 ppm) and TNP (60 ppm) exposure at sub-lethal concentration for 24 h in zebrafish...
December 27, 2017: Environmental Toxicology and Pharmacology
https://www.readbyqxmd.com/read/29330169/inter-rater-reliability-in-the-paediatric-observation-priority-score-pops
#5
Lisa Langton, Adam Bonfield, Damian Roland
OBJECTIVE: The primary objective of this study was to determine the level of inter-rater reliability between nursing staff for the Paediatric Observation Priority Score (POPS). DESIGN: Retrospective observational study. SETTING: Single-centre paediatric emergency department. PARTICIPANTS: 12 participants from a convenience sample of 21 nursing staff. INTERVENTIONS: Participants were shown video footage of three pre-recorded paediatric assessments and asked to record their own POPS for each child...
January 12, 2018: Archives of Disease in Childhood
https://www.readbyqxmd.com/read/29329017/amiodarone-a-multi-channel-blocker-enhances-anticonvulsive-effect-of-carbamazepine-in-the-mouse-maximal-electroshock-model
#6
Monika Banach, Monika Popławska, Kinga K Borowicz-Reutt
Cardiac arrhythmia may occur in the course of epilepsy. Simultaneous therapy of the two diseases might be complicated by drug interactions since antiarrhythmic and antiepileptic agents share some molecular targets. The aim of this study was to evaluate the influence of amiodarone, an antiarrhythmic drug working as a multi-channel blocker, on the protective activity of four classical antiepileptic drugs in the maximal electroshock test in mice. Amiodarone at doses up to 75 mg/kg did not affect the electroconvulsive threshold in mice...
January 5, 2018: Epilepsy Research
https://www.readbyqxmd.com/read/29327093/mir-181-family-specific-behavior-in-different-cancers-a-meta-analysis-view
#7
Cecilia Pop-Bica, Sebastian Pintea, Roxana Cojocneanu-Petric, Giannino Del Sal, Silvano Piazza, Zhao-Hui Wu, Alvaro J Alencar, Izidore S Lossos, Ioana Berindan-Neagoe, George A Calin
The involvement of microRNAs in malignant transformation and cancer progression was previously grounded. The observations made by multiple published studies led to the conclusion that some of these small sequences could be eventually used as biomarkers for diagnosis/prognosis. This meta-analysis investigated whether microRNA-181 family members could predict the outcome of patients carrying different types of cancer. We searched the PubMed and Embase databases for studies evaluating the expression levels of miR-181a/b/c/d in patients with cancer, selecting the publications that assessed the relation between low and high levels of one of these four microRNAs and patients' outcome...
January 11, 2018: Cancer Metastasis Reviews
https://www.readbyqxmd.com/read/29326113/acute-heart-failure-with-new-onset-continuous-murmur-in-a-26-year-old-man
#8
Yi-Chen Wang, Chen-Wei Huang, Ting-Wei Lin
CLINICAL INTRODUCTION: A 26-year-old man with an unremarkable medical history sensed a momentary retrosternal 'pop' followed by overwhelming dyspnoea, without reporting any prodromal symptoms. At the emergency department, he had a significant tachycardia (170 bpm) and an extreme low diastolic blood pressure (<30 mm Hg). A loud, harsh and continuous murmur could be maximally auscultated at the right lower sternal border. ECG revealed global ST depression with ST elevation in lead aVR...
January 11, 2018: Heart: Official Journal of the British Cardiac Society
https://www.readbyqxmd.com/read/29324569/does-the-vaginal-flora-modify-when-a-synthetic-mesh-is-used-for-genital-prolapse-repair-in-postmenopausal-women-a-pilot-randomized-controlled-study
#9
Edilson Benedito de Castro, Luiz Gustavo Oliveria Brito, Paulo César Giraldo, Cássia Raquel Teatin Juliato
OBJECTIVE: The vaginal flora from postmenopausal women with pelvic organ prolapse (POP) is different from younger women. We hypothesized that the decision of a surgical route using a mesh would modify the vaginal flora. The purpose of this study was to analyze the vaginal flora from postmenopausal women that were submitted to abdominal sacrocervicopexy or vaginal sacrospinous fixation. METHODS: A pilot, randomized controlled study with 50 women aged 55 to 75 years (n = 25; abdominal sacrocervicopexy + subtotal hysterectomy; n = 25 vaginal sacrospinous fixation + vaginal hysterectomy) was performed...
January 10, 2018: Female Pelvic Medicine & Reconstructive Surgery
https://www.readbyqxmd.com/read/29322213/translation-and-validation-of-the-international-consultation-on-incontinence-questionnaire-vaginal-symptoms-iciq-vs-the-danish-version
#10
Louise Thomsen Schmidt Arenholt, Marianne Glavind-Kristensen, Henrik Bøggild, Karin Glavind
INTRODUCTION: In the clinical evaluation of women with pelvic organ prolapse (POP), it is important to evaluate both objective and subjective presentations. The objective evaluation is done by gynecological examination, but the subjective presentation is more complex. The International Consultation on Incontinence Questionnaire-Vaginal Symptoms (ICIQ-VS) is an important tool for subjective evaluation, and a Danish version was developed. MATERIALS AND METHODS: The English version was translated into Danish in accordance with guidelines...
January 10, 2018: International Urogynecology Journal
https://www.readbyqxmd.com/read/29322165/visual-search-in-barn-owls-task-difficulty-and-saccadic-behavior
#11
Julius Orlowski, Ohad Ben-Shahar, Hermann Wagner
How do we find what we are looking for? A target can be in plain view, but it may be detected only after extensive search. During a search we make directed attentional deployments like saccades to segment the scene until we detect the target. Depending on difficulty, the search may be fast with few attentional deployments or slow with many, shorter deployments. Here we study visual search in barn owls by tracking their overt attentional deployments-that is, their head movements-with a camera. We conducted a low-contrast feature search, a high-contrast orientation conjunction search, and a low-contrast orientation conjunction search, each with set sizes varying from 16 to 64 items...
January 1, 2018: Journal of Vision
https://www.readbyqxmd.com/read/29322155/can-the-stockholm-convention-address-the-spectrum-of-chemicals-currently-under-regulatory-scrutiny-advocating-a-more-prominent-role-for-modeling-in-pop-screening-assessment
#12
Michael S McLachlan
Frameworks for chemical regulation are based on the science at the time they were written. Today some regulations are being applied to a much broader spectrum of chemicals than we had knowledge of when the regulations were written. This entails a risk that the regulations are being used outside of their chemical application domain. This question is explored using the POP screening assessment in the Stockholm convention, which was developed 20 years ago. Using perfluorinated alkyl acids (PFAAs) as an example, it is shown that the assessment can lead to false negative conclusions...
January 11, 2018: Environmental Science. Processes & Impacts
https://www.readbyqxmd.com/read/29320920/patency-of-uterine-wall-in-pregnancies-following-assisted-and-spontaneous-conception-with-antecedent-laparoscopic-and-abdominal-myomectomies-a-difficult-case-and-systematic-review
#13
Lucian Pop, Ioan Dumitru Suciu, Daniela Oprescu, Romeo Micu, Silvia Stoicescu, Ebrahim Forouqi, Peter Sipos
No abstract text is available yet for this article.
January 10, 2018: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/29317314/phi-in-physiology-psychology-and-biomechanics-the-golden-ratio-between-myth-and-science
#14
REVIEW
Marco Iosa, Giovanni Morone, Stefano Paolucci
In recent years, there has been a renewed interest in the use of the so-called golden ratio (Phi, ϕ), an irrational number with fractal properties, used in artworks since V century BC. and now for modelling complex biological structures and functions. This number, in fact, recursively pops-up in human history, from Ancient Greeks to Renaissance, and to contemporary scientific studies. Nevertheless, recent scientific results often fall between two extremes: those of a priori sceptic researchers accusing the artificial emergence of ϕ in many studies, and those of researchers that find a mystic meaning in the presence of ϕ in human physiology...
January 6, 2018: Bio Systems
https://www.readbyqxmd.com/read/29317036/the-breast-cancer-screening-arcade-and-the-whack-a-mole-efforts-to-reduce-access-to-screening
#15
Daniel B Kopans
The effort to reduce access to breast cancer screening has been going on for decades. As each piece of misinformation has been published, scientific responses have exposed the fallacies, but then new "alternative facts" are generated. The effort has been compared to the arcade game "Whack-a-Mole" in which one false argument is addressed only to have a new one "pop up" to replace it. This has ranged from the false claim that early detection would have no effect on breast cancer, to the fallacious idea that early detection was leading to early deaths among young women, to the more recent false suggestion that tens of thousands of breast cancers found by mammography would disappear if left undetected...
February 2018: Seminars in Ultrasound, CT, and MR
https://www.readbyqxmd.com/read/29315917/covalent-bonding-of-thermoplastics-to-rubbers-for-printable-reel-to-reel-processing-in-soft-robotics-and-microfluidics
#16
Jay M Taylor, Karla Perez-Toralla, Ruby Aispuro, Stephen A Morin
The lamination of mechanically stiff structures to elastic materials is prevalent in biological systems and popular in many emerging synthetic systems, such as soft robotics, microfluidics, stretchable electronics, and pop-up assemblies. The disparate mechanical and chemical properties of these materials have made it challenging to develop universal synthetic procedures capable of reliably adhering to these classes of materials together. Herein, a simple and scalable procedure is described that is capable of covalently laminating a variety of commodity ("off-the-shelf") thermoplastic sheets to silicone rubber films...
January 8, 2018: Advanced Materials
https://www.readbyqxmd.com/read/29315250/blockchain-based-decentralized-management-of-demand-response-programs-in-smart-energy-grids
#17
Claudia Pop, Tudor Cioara, Marcel Antal, Ionut Anghel, Ioan Salomie, Massimo Bertoncini
In this paper, we investigate the use of decentralized blockchain mechanisms for delivering transparent, secure, reliable, and timely energy flexibility, under the form of adaptation of energy demand profiles of Distributed Energy Prosumers, to all the stakeholders involved in the flexibility markets (Distribution System Operators primarily, retailers, aggregators, etc.). In our approach, a blockchain based distributed ledger stores in a tamper proof manner the energy prosumption information collected from Internet of Things smart metering devices, while self-enforcing smart contracts programmatically define the expected energy flexibility at the level of each prosumer, the associated rewards or penalties, and the rules for balancing the energy demand with the energy production at grid level...
January 9, 2018: Sensors
https://www.readbyqxmd.com/read/29314710/different-in-vitro-and-in-vivo-tools-for-elucidating-the-human-metabolism-of-alpha-cathinone-derived-drugs-of-abuse
#18
Sascha K Manier, Lilian H J Richter, Jan Schäper, Hans H Maurer, Markus R Meyer
In vitro and in vivo experiments are widely used for studying the metabolism of new psychoactive substances (NPS). The availability of such data is required for toxicological risk assessments and development of urine screening approaches. This study investigated the in vitro metabolism of the five pyrrolidinophenone-derived NPS alpha-pyrrolidinobutyrophenone (alpha-PBP), alpha-pyrrolidinopentiothiophenone (alpha-PVT), alpha-pyrrolidinohexanophenone (alpha-PHP), alpha-pyrrolidinoenanthophenone (alpha-PEP, PV8), and alpha-pyrrolidinooctanophenone (alpha-POP, PV9)...
January 4, 2018: Drug Testing and Analysis
https://www.readbyqxmd.com/read/29306643/drug-induced-thrombocytopenia-after-anticoagulation-with-rivaroxaban
#19
Marianne K Pop, Farhad Farokhi, Lela Iduna
A 66-year-old man presented to the emergency department with complaints of dark-colored stool and rash developing over the last couple of days. The patient was started on rivaroxaban and flecainide for months prior for atrial fibrillation. Upon arrival, he was awake, alert, and oriented with a blood pressure of 111/63mmHg, heart rate of 68 beats per minute, and oxygen saturation of 96% on room air. A review of systems was unremarkable with the exception of skin rash and light-headedness. The patient's initial laboratory results were significant for red blood cell (RBC) count of 4...
December 24, 2017: American Journal of Emergency Medicine
https://www.readbyqxmd.com/read/29306590/new-definition-criteria-of-myocardial-dysfunction-in-patients-with-liver-cirrhosis-a-speckle-tracking-and-tissue-doppler-imaging-study
#20
Roxana Cristina Rimbaş, Sorina Mihăilă Baldea, Ruxandra Drăgoi Galrinho Antunes Guerra, Simona Ionela Visoiu, Mihai Rimbaş, Corina Silvia Pop, Dragoş Vinereanu
There are no clear recommendations regarding cirrhotic cardiomyopathy (CC) evaluation in patients with pre-transplant liver cirrhosis. The roles of new methods, tissue Doppler imaging (TDI) and speckle tracking echocardiography (STE) in the diagnosis and prognosis of cirrhotic cardiomyopathy remain controversial. We investigated the utility of TDI/STE parameters in cirrhotic cardiomyopathy diagnosis and also in predicting mortality in patients with liver cirrhosis. Left/right ventricular function was studied using conventional TDI (velocities) and STE (strain/strain rate)...
January 3, 2018: Ultrasound in Medicine & Biology
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