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https://www.readbyqxmd.com/read/28194143/novel-immunity-proteins-associated-with-colicin-m-like-bacteriocins-exhibit-promiscuous-protection-in-pseudomonas
#1
Maarten G K Ghequire, Lieselore Kemland, René De Mot
Bacteriocins related to colicin M, acting via cleavage of the cell wall precursor lipid II, have been characterized in γ- and β-proteobacteria. Depending on the species, immunity is provided by either an inner membrane-anchored periplasmic protein or by an integral membrane protein. In Pseudomonas however, the immunity partner of colicin M-like bacteriocins remains unknown. Based on an in silico analysis in pseudomonad genomes, we here identify a gene encoding a putative immunity partner that represents a novel type of integral membrane protein (PmiA, Pseudomonas colicin M-like immunity type A)...
2017: Frontiers in Microbiology
https://www.readbyqxmd.com/read/28161171/technical-note-effects-of-attachment-of-hind-teats-before-cleaning-and-attachment-of-front-teats-on-milking-characteristics-in-automatic-milking-systems
#2
J Besier, G Schüpbach-Regula, O Wellnitz, R M Bruckmaier
Milking characteristics differ between the 4 quarters of a dairy cow udder. In particular, milking time is mostly prolonged in hind quarters compared with front quarters because of the usually higher amount of stored milk. The standard milking routine (STDMR) in both conventional and automatic milking systems (AMS) consists of teat preparation of all 4 quarters, followed by attachment of the 4 teat cups, regardless of the distribution of milk between quarters. In the current study, an alternative teat preparation and milking routine (ALTMR) in AMS was tested, which consisted of cleaning and starting the milking of hind teats before cleaning and attachment of front teats...
February 1, 2017: Journal of Dairy Science
https://www.readbyqxmd.com/read/28139357/morphological-brain-changes-associated-with-negative-symptoms-in-patients-with-22q11-2-deletion-syndrome
#3
Angeline Mihailov, Maria Carmela Padula, Elisa Scariati, Marie Schaer, Maude Schneider, Stephan Eliez
Approximately 30% of individuals with 22q11.2 Deletion Syndrome (22q11DS) develop schizophrenia during adolescence/early adulthood, making this syndrome a model for the disorder. Furthermore, negative symptoms exist in up to 80% of patients diagnosed with 22q11DS. The present study aims to uncover morphological brain alterations associated with negative symptoms in a cohort of patients with 22q11DS who are at-risk for developing schizophrenia. A total of 71 patients with 22q11DS aged 12 to 35 (54% females) with no past or present diagnosis of a schizophrenia were included in the study...
January 27, 2017: Schizophrenia Research
https://www.readbyqxmd.com/read/28130552/melatonin-micronutrients-osteopenia-treatment-study-mots-a-translational-study-assessing-melatonin-strontium-citrate-vitamin-d3-and-vitamin-k2-mk7-on-bone-density-bone-marker-turnover-and-health-related-quality-of-life-in-postmenopausal-osteopenic-women-following
#4
Sifat Maria, Mark H Swanson, Larry T Enderby, Frank D'Amico, Brianna Enderby, Rebekah M Samsonraj, Amel Dudakovic, Andre J van Wijnen, Paula A Witt-Enderby
This one-year double blind randomized control trial assessed the effects of nightly melatonin, strontium (citrate), vitamin D3 and vitamin K2 (MK7; MSDK) on bone mineral density (BMD) and quality of life (QOL) in postmenopausal osteopenic women (ages 49-75). Compared to placebo, MSDK treatment increased BMD in lumbar spine (4.3%) and left femoral neck (2.2%), with an upward trend for total left hip (p=0.069). MSDK increased serum P1NP levels and reduced bone turnover (CTx:P1NP). Psychometric analyses indicated that mood and sleep quality improved for the MSDK group...
January 26, 2017: Aging
https://www.readbyqxmd.com/read/28127511/high-angular-resolution-diffusion-imaging-tractography-of-cerebellar-pathways-from-newborns-to-young-adults
#5
Thomas J Re, Jacob Levman, Ashley R Lim, Andrea Righini, Patricia Ellen Grant, Emi Takahashi
INTRODUCTION: Many neurologic and psychiatric disorders are thought to be due to, or result in, developmental errors in neuronal cerebellar connectivity. In this connectivity analysis, we studied the developmental time-course of cerebellar peduncle pathways in pediatric and young adult subjects. METHODS: A cohort of 80 subjects, newborns to young adults, was studied on a 3T MR system with 30 diffusion-weighted measurements with high-angular resolution diffusion imaging (HARDI) tractography...
January 2017: Brain and Behavior
https://www.readbyqxmd.com/read/28114965/synergistic-antibacterial-effect-of-co-administering-adipose-derived-mesenchymal-stromal-cells-and-ophiophagus-hannah-l-amino-acid-oxidase-in-a-mouse-model-of-methicillin-resistant-staphylococcus-aureus-infected-wounds
#6
Yee Yik Mot, Iekhsan Othman, Syed Hassan Sharifah
BACKGROUND: Mesenchymal stromal cells (MSCs) and Ophiophagus hannah L-amino acid oxidase (Oh-LAAO) have been reported to exhibit antimicrobial activity against methicillin-resistant Staphylococcus aureus (MRSA). Published data have indicated that synergistic antibacterial effects could be achieved by co-administration of two or more antimicrobial agents. However, this hypothesis has not been proven in a cell- and protein-based combination. In this study, we investigate if co-administration of adipose-derived MSCs and Oh-LAAO into a mouse model of MRSA-infected wounds would be able to result in a synergistic antibacterial effect...
January 23, 2017: Stem Cell Research & Therapy
https://www.readbyqxmd.com/read/28112718/erratum-indexing-the-pseudomonas-specialized-metabolome-enabled-the-discovery-of-poaeamide-b-and-the-bananamides
#7
Don D Nguyen, Alexey V Melnik, Nobuhiro Koyama, Xiaowen Lu, Michelle Schorn, Jinshu Fang, Kristen Aguinaldo, Tommie L Lincecum, Maarten G K Ghequire, Victor J Carrion, Tina L Cheng, Brendan M Duggan, Jacob G Malone, Tim H Mauchline, Laura M Sanchez, A Marm Kilpatrick, Jos M Raaijmakers, René De Mot, Bradley S Moore, Marnix H Medema, Pieter C Dorrestein
No abstract text is available yet for this article.
January 23, 2017: Nature Microbiology
https://www.readbyqxmd.com/read/28111352/the-effect-of-negative-emotion-on-multiple-object-tracking-task-an-erp-study
#8
Jing Su, Dongyuan Duan, Xuemin Zhang, Huanyu Lei, Chundi Wang, Heng Guo, Xiaoqian Yan
Previous studies have revealed that negative emotion may influence participants' cognitive processing. However, the neural mechanism of the impact of negative emotion on dynamic task like Multiple Object Tracking (MOT) is still unknown. This present study used electrophysiological (Event-Related Potentials, ERP) measures to investigate the effect of negative emotion on MOT tasks. Participants were required to complete MOT tasks while detecting the probe dots that would appear on targets, distractors or the space between them during tracking...
January 19, 2017: Neuroscience Letters
https://www.readbyqxmd.com/read/28111190/increased-sensitivity-to-age-related-differences-in-brain-functional-connectivity-during-continuous-multiple-object-tracking-compared-to-resting-state
#9
Erlend S Dørum, Tobias Kaufmann, Dag Alnæs, Ole A Andreassen, Geneviève Richard, Knut K Kolskår, Jan Egil Nordvik, Lars T Westlye
Age-related differences in cognitive agility vary greatly between individuals and cognitive functions. This heterogeneity is partly mirrored in individual differences in brain network connectivity as revealed using resting-state functional magnetic resonance imaging (fMRI), suggesting potential imaging biomarkers for age-related cognitive decline. However, although convenient in its simplicity, the resting state is essentially an unconstrained paradigm with minimal experimental control. Here, based on the conception that the magnitude and characteristics of age-related differences in brain connectivity is dependent on cognitive context and effort, we tested the hypothesis that experimentally increasing cognitive load boosts the sensitivity to age and changes the discriminative network configurations...
January 20, 2017: NeuroImage
https://www.readbyqxmd.com/read/28081584/-mini-open-approach-shows-good-results-in-treatment-of-femoroacetabular-impingement
#10
Stephanie Maria Kirschbaum, Frank Sitterlee, Carsten Perka, Michael Müller
Background Femoroacetabular impingement (FAI) describes a painful, abnormal (bony) contact between the femoral neck and acetabulum, which, if left untreated, contributes to early osteoarthritis (OA) of the hip. Despite its flat learning curve and long operation times, hip arthroscopy has been used increasingly often in recent years in the surgery of femoroacetabular impingement. The mini-open technique (MOT) offers a possible alternative that addresses the abnormal morphological prominence and allows minimally invasive clearance of hip motion...
January 12, 2017: Zeitschrift Für Orthopädie und Unfallchirurgie
https://www.readbyqxmd.com/read/28070613/the-plant-growth-promoting-effect-of-the-nitrogen-fixing-endophyte-pseudomonas-stutzeri-a15
#11
Van T K Pham, Hans Rediers, Maarten G K Ghequire, Hiep H Nguyen, René De Mot, Jos Vanderleyden, Stijn Spaepen
The use of plant growth-promoting rhizobacteria as a sustainable alternative for chemical nitrogen fertilizers has been explored for many economically important crops. For one such strain isolated from rice rhizosphere and endosphere, nitrogen-fixing Pseudomonas stutzeri A15, unequivocal evidence of the plant growth-promoting effect and the potential contribution of biological nitrogen fixation (BNF) is still lacking. In this study, we investigated the effect of P. stutzeri A15 inoculation on the growth of rice seedlings in greenhouse conditions...
January 9, 2017: Archives of Microbiology
https://www.readbyqxmd.com/read/28063626/effect-of-chamber-characteristics-loading-and-analysis-time-on-motility-and-kinetic-variables-analysed-with-the-casa-mot-system-in-goat-sperm
#12
COMPARATIVE STUDY
R Del Gallego, S Sadeghi, E Blasco, C Soler, J L Yániz, M A Silvestre
Several factors unrelated to the semen samples could be influencing in the sperm motility analysis. The aim of the present research was to study the effect of four chambers with different characteristics, namely; slide-coverslip, Spermtrack, ISAS D4C10, and ISAS D4C20 on the sperm motility. The filling procedure (drop or capillarity) and analysis time (0, 120 and 240s), depth of chamber (10 or 20μm) and field on motility variables were analysed by use of the CASA-mot system in goat sperm. Use of the drop-filling chambers resulted in greater values than capillarity-filling chambers for all sperm motility and kinetic variables, except for LIN (64...
February 2017: Animal Reproduction Science
https://www.readbyqxmd.com/read/28063574/interventions-et-techniques-de-diagnostic-pr%C3%A3-natal-visant-l-obtention-d-un-pr%C3%A3-l%C3%A3-vement-f%C3%A5-tal-%C3%A3-des-fins-diagnostiques-risques-et-avantages-pour-la-m%C3%A3-re-et-le-f%C3%A5-tus
#13
R Douglas Wilson, Alain Gagnon, François Audibert, Carla Campagnolo, June Carroll
OBJECTIF: Offrir aux fournisseurs de soins de maternité et à leurs patientes des lignes directrices factuelles contemporaines en ce qui concerne les services de counseling traitant des risques et des avantages maternels propres à la tenue des interventions diagnostiques prénatales orientées par échographie (et/ou des techniques permettant l'établissement d'un diagnostic génétique) nécessaires dans les cas où il a été établi pendant la période prénatale que la grossesse serait exposée à des risques, ainsi qu'en ce qui concerne la prise de décisions subséquentes quant à la prise en charge de la grossesse (questions abordant des aspects tels que le niveau du fournisseur de soins obstétricaux, la surveillance prénatale, le lieu où devraient se dérouler les soins et l'accouchement, et la décision de poursuivre ou d'interrompre la grossesse)...
December 2016: Journal of Obstetrics and Gynaecology Canada: JOGC, Journal D'obstétrique et Gynécologie du Canada: JOGC
https://www.readbyqxmd.com/read/28063572/suppl%C3%A3-mentation-pr%C3%A3-conceptionnelle-en-acide-folique-multivitamines-pour-la-pr%C3%A3-vention-primaire-et-secondaire-des-anomalies-du-tube-neural-et-d-autres-anomalies-cong%C3%A3-nitales-sensibles-%C3%A3-l-acide-folique
#14
R Douglas Wilson
OBJECTIF: Offrir des renseignements à jour sur l'utilisation pré et postconceptionnelle d'acide folique par voie orale, avec ou sans supplément de multivitamines / micronutriments, aux fins de la prévention des anomalies du tube neural et d'autres anomalies congénitales. Ces renseignements aideront les médecins, les sages-femmes, les infirmières et les autres professionnels de la santé à contribuer aux efforts de sensibilisation des femmes quant à l'utilisation et aux posologies adéquates de la supplémentation en acide folique / multivitamines, avant et pendant la grossesse...
December 2016: Journal of Obstetrics and Gynaecology Canada: JOGC, Journal D'obstétrique et Gynécologie du Canada: JOGC
https://www.readbyqxmd.com/read/28063569/prise-en-charge-des-fibromes-ut%C3%A3-rins-en-pr%C3%A3-sence-d-une-infertilit%C3%A3-autrement-inexpliqu%C3%A3-e
#15
Belina Carranza-Mamane, Jon Havelock, Robert Hemmings
OBJECTIF: Formuler des recommandations quant à la façon optimale d'assurer la prise en charge des fibromes dans le contexte de l'infertilité. Les options habituelles et novatrices de prise en charge des fibromes seront analysées en mettant l'accent sur leur applicabilité chez les femmes qui souhaitent obtenir une grossesse. OPTIONS: La prise en charge des fibromes chez les femmes qui souhaitent obtenir une grossesse met d'abord en jeu la documentation de la présence des fibromes en question et la détermination de la probabilité que ces derniers affectent le potentiel génésique...
December 2016: Journal of Obstetrics and Gynaecology Canada: JOGC, Journal D'obstétrique et Gynécologie du Canada: JOGC
https://www.readbyqxmd.com/read/28063567/vulvovaginite-d%C3%A3-pistage-et-prise-en-charge-de-la-trichomonase-de-la-candidose-vulvovaginale-et-de-la-vaginose-bact%C3%A3-rienne
#16
Julie van Schalkwyk, Mark H Yudin
OBJECTIF: Analyser les données probantes et formuler des recommandations quant au dépistage et à la prise en charge de la candidose vulvovaginale, de la trichomonase et de la vaginose bactérienne. ISSUES: Parmi les issues évaluées, on trouve l'efficacité de l'antibiothérapie, les taux de guérison en ce qui concerne les infections simples et compliquées, et les implications de ces pathologies pendant la grossesse. RéSULTATS: La littérature publiée a été récupérée par l'intermédiaire de recherches menées dans MEDLINE, EMBASE, CINAHL et The Cochrane Library en juin 2013 au moyen d'un vocabulaire contrôlé (p...
December 2016: Journal of Obstetrics and Gynaecology Canada: JOGC, Journal D'obstétrique et Gynécologie du Canada: JOGC
https://www.readbyqxmd.com/read/28063558/ost%C3%A3-oporose-pendant-la-m%C3%A3-nopause
#17
Aliya Khan, Michel Fortier
OBJECTIF: Offrir aux fournisseurs de soins de santé des lignes directrices quant à la prévention, au diagnostic et à la prise en charge clinique de l'ostéoporose postménopausique. ISSUES: Stratégies visant à identifier et à évaluer les femmes exposées à des risques élevés; utilisation de la densité minérale osseuse et des marqueurs du renouvellement des cellules osseuses pour l'évaluation du diagnostic et de la réaction à la prise en charge; et recommandations quant à la nutrition, à l'activité physique et au choix du traitement pharmacologique en vue de prévenir l'ostéoporose et d'en assurer la prise en charge...
December 2016: Journal of Obstetrics and Gynaecology Canada: JOGC, Journal D'obstétrique et Gynécologie du Canada: JOGC
https://www.readbyqxmd.com/read/28063550/d%C3%A3-termination-de-l-%C3%A3-ge-gestationnel-par-%C3%A3-chographie
#18
Kimberly Butt, Ken Lim
OBJECTIF: Aider les cliniciens à attribuer un âge gestationnel en fonction des résultats de la biométrie échographique. ISSUES: Déterminer si la datation par échographie offre une évaluation plus précise de l'âge gestationnel que la datation en fonction des dernières règles avec ou sans recours à l'échographie. Offrir, aux praticiens et aux chercheurs du domaine des soins de maternité, des lignes directrices factuelles en matière d'attribution de l'âge gestationnel...
December 2016: Journal of Obstetrics and Gynaecology Canada: JOGC, Journal D'obstétrique et Gynécologie du Canada: JOGC
https://www.readbyqxmd.com/read/28063549/insuffisance-cervicale-et-cerclage-cervical
#19
Richard Brown, Robert Gagnon, Marie-France Delisle
OBJECTIF: La présente directive clinique a pour but de fournir un cadre de référence que les cliniciens pourront utiliser pour identifier les femmes qui sont exposées aux plus grands risques de connaître une insuffisance cervicale, ainsi que pour déterminer les circonstances en présence desquelles la mise en place d'un cerclage pourrait s'avérer souhaitable. RéSULTATS: La littérature publiée a été récupérée par l'intermédiaire de recherches menées dans PubMed ou MEDLINE, CINAHL et The Cochrane Library en 2012 au moyen d'un vocabulaire contrôlé (p...
December 2016: Journal of Obstetrics and Gynaecology Canada: JOGC, Journal D'obstétrique et Gynécologie du Canada: JOGC
https://www.readbyqxmd.com/read/28063545/pr%C3%A3-vention-de-l-infection-n%C3%A3-onatale-%C3%A3-streptocoques-du-groupe-b-d-apparition-pr%C3%A3-coce
#20
Deborah Money, Victoria M Allen
OBJECTIF: Analyser les données issues de la littérature et formuler des recommandations sur la prise en charge des parturientes en vue de prévenir l'infection néonatale à streptocoques du groupe B d'apparition précoce. Parmi les révisions clés que renferme la présente directive clinique mise à jour, on trouve des modifications quant aux recommandations en ce qui concerne les schémas posologiques d'antibioprophylaxie, les épreuves de sensibilité et la prise en charge des femmes présentant une rupture prématurée des membranes...
December 2016: Journal of Obstetrics and Gynaecology Canada: JOGC, Journal D'obstétrique et Gynécologie du Canada: JOGC
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