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https://www.readbyqxmd.com/read/28239468/immunotherapy-associated-autoimmune-hemolytic-anemia
#1
Uqba Khan, Farman Ali, Muhammad Siddique Khurram, Awais Zaka, Tarik Hadid
BACKGROUND: Immunotherapy has been widely used in the treatment of several solid and hematologic malignancies. Checkpoint inhibitors have been the forefront of cancer immunotherapy in recent years. Cytotoxic T-lymphocyte-associated protein 4 (CTLA-4) and programmed cell death 1 (PD-1) pathway are the prototypic checkpoint targets for immunotherapy. When combined, CTLA-4 and PD-1 checkpoint inhibitors work synergistically, but with increased probability of toxicity. The following case represents an unusual adverse effect of combined treatment with ipilimumab and nivolumab used for treatment of metastatic melanoma...
2017: Journal for Immunotherapy of Cancer
https://www.readbyqxmd.com/read/28237944/could-kinesiology-taping-help-mitigate-pain-breathlessness-and-abdominal-related-symptoms-in-cancer
#2
Gourav Banerjee, Alison Rose, Michelle Briggs, Mark I Johnson
We present the case of a woman who was an amateur athlete diagnosed with primary breast cancer, and 10 years later with terminal metastatic cancer. This case report was prepared posthumously in co-operation with her next of kin (husband). The patient first presented to a sports physiotherapist (AR) for her pain-management and to help maintain physical fitness so that she could continue with sports and an active lifestyle. The patient continued with physiotherapy for several months to enable her to be active...
February 24, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28236651/intravenous-fluid-rate-for-reduction-of-cesarean-delivery-rate-in-nulliparous-women-a-systematic-review-and-meta-analysis
#3
Robert M Ehsanipoor, Gabriele Saccone, Neil S Seligman, Rebecca Pierce-Williams, Andrea Ciardulli, Vincenzo Berghella
The National Institute of Child Health and Human Development, American College of Obstetricians and Gynecologists, and Society for Maternal-Fetal Medicine have emphasized the need to promote vaginal delivery and have offered recommendations to safely prevent primary cesarean delivery. However, there has been limited discussion regarding management of intravenous fluids and other aspects of labor management that may influence labor. Therefore the aim of our study was to determine if an intravenous fluid rate of 250 vs 125 mL/hour is associated with a difference in cesarean delivery rate MATERIAL AND METHODS: Searches were performed in Medline, OVID, Scopus, ClinicalTrials...
February 25, 2017: Acta Obstetricia et Gynecologica Scandinavica
https://www.readbyqxmd.com/read/28235525/iatrogenic-tracheal-laceration-in-the-setting-of-chronic-steroids
#4
Punit Singh, Margaret Wojnar, Anita Malhotra
We report the case of a 71-year-old woman with end-stage chronic obstructive pulmonary disease who presented with a 10-cm tracheal laceration from a presumed traumatic intubation in the setting of respiratory distress and chronic obstructive pulmonary disease exacerbation and subsequently developed significant subcutaneous emphysema along her neck and mediastinum in addition to her peritoneum and mesentery. We were successfully able to treat this patient conservatively up until the time that tracheostomy was warranted...
February 2017: Journal of Clinical Anesthesia
https://www.readbyqxmd.com/read/28228782/safety-and-effectiveness-of-teriparatide-vs-alendronate-in-postmenopausal-osteoporosis-a-prospective-non-randomized-clinical-study
#5
Gianfilippo Caggiari, Paolo Tranquilli Leali, Giulia Raffaella Mosele, Leonardo Puddu, Francesca Badessi, Carlo Doria
In this work we study the safety and effectiveness of teriparatide and alendronate in patients with postmenopausal osteoporosis at high risk of fracture; it was a double-blinded and it was done by examining the comparisons between teriparatide 20 μg/day and alendronate 10 mg/day. Safety and effectiveness analyses were based on data from 355 woman with a mean age of 68 years. Two groups (A and B) with T-score ≤-2.5 at bone mineral density were analyzed and 3 or more vertebral fractures on radiograph. Group A: was treated with teriparatide 20 μg/day and composed from 182 women, in post-menopausal age, without a history of cancer...
September 2016: Clinical Cases in Mineral and Bone Metabolism
https://www.readbyqxmd.com/read/28226067/-drug-abuse-and-eating-disorders-in-women-symptoms-of-gender-discomfort
#6
Regina Helena Simões-Barbosa, Sônia Maria Dantas-Berger
The article discusses drug abuse and eating disorders from the critical gender and healthcare perspectives, postulating that subjective suffering can be expressed in the body through psychosomatic illnesses. From this perspective, craving for drugs or superfluous consumer goods, just as illness from self-imposed hunger in pursuit of an ideal of slimness, as in anorexia and bulimia, can be symptoms that expose the woman's suffering. A review in the fields of public health and feminist theories highlights the magnitude of the phenomena of medicalization and commodification of health in the psychiatrization of female discomfort...
February 13, 2017: Cadernos de Saúde Pública
https://www.readbyqxmd.com/read/28220337/one-key-question-%C3%A2-first-things-first-in-reproductive-health
#7
Deborah Allen, Michele Stranger Hunter, Susan Wood, Tishra Beeson
Objectives Preconceptional health care is increasingly recognized as important to promotion of healthy birth outcomes. Preconceptional care offers an opportunity to influence pregnancy timing and intent and mother's health status prior to conception, all predictors of individual outcomes and of inequality in birth outcomes based on race, ethnicity and class. Methods One Key Question, a promising practice developed in Oregon which is now attracting national interest, provides an entry point into preconceptional care by calling on providers to screen for pregnancy intent in well woman and chronic disease care for women of reproductive age...
February 20, 2017: Maternal and Child Health Journal
https://www.readbyqxmd.com/read/28218687/uv-radiation-from-physics-to-impacts
#8
EDITORIAL
Hanns Moshammer, Stana Simic, Daniela Haluza
Ultraviolet (UV) radiation has affected life at least since the first life forms moved out of the seas and crawled onto the land. Therefore, one might assume that evolution has adapted to natural UV radiation. However, evolution is mostly concerned with the propagation of the genetic code, not with a long, happy, and fulfilling life. Because rickets is bad for a woman giving birth, the beneficial effects of UV-radiation outweigh the adverse effects like aged skin and skin tumors of various grades of malignancy that usually only afflict us at older age...
February 17, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/28217672/effects-of-vitamin-d-deficiency-and-daily-calcium-intake-on-bone-mineral-density-and-osteoporosis-in-korean-postmenopausal-woman
#9
Seung Joo Chon, Yae Kyu Koh, Jin Young Heo, Jinae Lee, Min Kyoung Kim, Bo Hyon Yun, Byung Seok Lee, Seok Kyo Seo
OBJECTIVE: We evaluated the combined effects of vitamin D and daily calcium intake on bone mineral density (BMD) and osteoporosis in Korean postmenopausal women. METHODS: This study is a cross-sectional study consisting of 1,921 Korean postmenopausal women aged 45 to 70 years without thyroid dysfunction, from the 2008-2011 Korean National Health and Nutrition Examination Survey. Participants were classified into six groups according to serum 25-hydroxyvitamin D (25(OH)D) levels and daily calcium intake...
January 2017: Obstetrics & Gynecology Science
https://www.readbyqxmd.com/read/28217616/cocaine-induced-vasculitis-with-cutaneous-manifestation-a-recurrent-episode-after-2-years
#10
Thein Swe, Mona Pervil-Ulysse, Aam A Baqui
Cocaine is a popular recreational drug in the United States, and up to 70% of the seized cocaine contains levamisole which is an antihelminthic that can cause cutaneous vasculitis with necrosis and positive antineutrophil cytoplasmic antibodies (ANCAs). Here, we report a unique case of recurrent cocaine-induced vasculitis in a patient who smokes cocaine for more than 20 years. A 38-year-old woman complained of painful erythematous rash in her right arm and right thigh which appeared some hours after smoking cocaine...
July 2016: Journal of Family Medicine and Primary Care
https://www.readbyqxmd.com/read/28216499/-risk-factors-for-nausea-and-vomiting-in-pregnant-women-%C3%A2-in-changsha
#11
Shiting Xiang, Yan Yan, Xiao Gao, Hongyan Li, Shan Tan, Qiong He, Tingting Sha, Shiping Liu, Guangyu Zeng, Qiang Yan
To explore the risk factors for nausea and vomiting in pregnant women.
 Methods: Using cluster random sampling method and following the exclusion and inclusion criteria, a total of 713 pregnant women from the health service center of 3 street communities in Changsha city district were enrolled. Statistical analysis was used to analyze the relevant influential factors for nausea and vomiting.
 Results: Vomiting incidence in pregnant women was 59.6%. The risk factors for nausea and vomiting were female fetus (OR=1...
January 28, 2017: Zhong Nan da Xue Xue Bao. Yi Xue Ban, Journal of Central South University. Medical Sciences
https://www.readbyqxmd.com/read/28216190/evaluation-of-two-vaccine-education-interventions-to-improve-pertussis-vaccination-among-pregnant-african-american-women-a-randomized-controlled-trial
#12
Jennifer L Kriss, Paula M Frew, Marielysse Cortes, Fauzia A Malik, Allison T Chamberlain, Katherine Seib, Lisa Flowers, Kevin A Ault, Penelope P Howards, Walter A Orenstein, Saad B Omer
BACKGROUND: Vaccination coverage with tetanus toxoid, reduced diphtheria toxoid, and acellular pertussis (Tdap) vaccine in pregnancy or immediately postpartum has been low. Limited data exist on rigorously evaluated interventions to increase maternal vaccination, including Tdap. Tailored messaging based on the Elaboration Likelihood Model (ELM) framework has been successful in improving uptake of some public health interventions. We evaluated the effect of two ELM-based vaccine educational interventions on Tdap vaccination among pregnant African American women, a group of women who tend to have lower vaccine uptake compared with other groups...
February 16, 2017: Vaccine
https://www.readbyqxmd.com/read/28214469/cost-benefit-analysis-of-chlamydia-trachomatis-screening-in-pregnant-women-in-a-high-burden-setting-in-the-united-states
#13
Jared Ditkowsky, Khushal H Shah, Margaret R Hammerschlag, Stephan Kohlhoff, Tamar A Smith-Norowitz
BACKGROUND: Chlamydia trachomatis is the most common bacterial sexually transmitted infection (STI) in the United States (U.S.) [1] and remains a major public health problem. We determined the cost- benefit of screening all pregnant women aged 15-24 for Chlamydia trachomatis infection compared with no screening. METHODS: We developed a decision analysis model to estimate costs and health-related effects of screening pregnant women for C. trachomatis in a high burden setting (Brooklyn, NY)...
February 18, 2017: BMC Infectious Diseases
https://www.readbyqxmd.com/read/28211217/breast-shape-ptosis-as-a-marker-of-a-woman-s-breast-attractiveness-and-age-evidence-from-poland-and-papua
#14
Agata Groyecka, Agnieszka Żelaźniewicz, Michał Misiak, Maciej Karwowski, Piotr Sorokowski
OBJECTIVES: A women's breast is a sex-specific and aesthetic bodily attribute. It is suggested that breast morphology signals maturity, health, and fecundity. The perception of a woman's attractiveness and age depends on various cues, such as breast size or areola pigmentation. Conducted in Poland and Papua, the current study investigated how breast attractiveness, and the further estimate of a woman's age based on her breast's appearance, is affected by the occurrence of breast ptosis (ie, sagginess, droopiness)...
February 17, 2017: American Journal of Human Biology: the Official Journal of the Human Biology Council
https://www.readbyqxmd.com/read/28211155/utah-obstetricians-opinions-of-planned-home-birth-and-conflicting-nice-acog-guidelines-a-qualitative-study
#15
Emily Rainey, Sara Simonsen, Joseph Stanford, Kimberley Shoaf, Jami Baayd
BACKGROUND: The United Kingdom's National Institute for Health and Care Excellence (NICE) recently published recommendations that support planned home birth for low-risk women. The American College of Obstetricians and Gynecologists (ACOG) remains wary of planned home birth, asserting that hospitals and birthing centers are the safest birth settings. Our objective was to examine opinions of obstetricians in Salt Lake City, Utah about home birth in the context of rising home birth rates and conflicting guidelines...
February 17, 2017: Birth
https://www.readbyqxmd.com/read/28210013/the-relation-between-depressive-symptoms-and-self-care-in-patients-with-diabetes-mellitus-type-2-in-kosovo
#16
Idriz Sopjani, Shemsedin Vehapi, Daut Gorani, Miradije Imeri, Sidita Vitoja, Shqipe Tahiri
BACKGROUND: The depression is a significant problem in patients with diabetes. This research is the first of it's kind conducted in the Republic of Kosovo to determine the prevalence of depression diagnosed in people with diabetes mellitus type 2 (DMT2) and interrelation between depressive symptoms and behavior of diabetes self-care (glucose monitoring, exercise, diet, and self- health care). METHODS: Research was conducted in the University Clinical Center of Kosovo (UCCK), in Pristine...
December 2016: Medical Archives
https://www.readbyqxmd.com/read/28207749/determinants-of-first-trimester-attendance-at-antenatal-care-clinics-in-the-amazon-region-of-peru-a-case-control-study
#17
Nora Moore, Brittany Blouin, Hugo Razuri, Martin Casapia, Theresa W Gyorkos
OBJECTIVE: To identify determinants which influence the timing of the first antenatal care (ANC) visit in pregnant women. DESIGN: Retrospective matched nested case-control study. SETTING: Two health centres, Belén and 6 de Octubre, in the Peruvian Amazon. POPULATION: All pregnant women who had attended ANC during the years 2010, 2011, and 2012. METHODS: All cases (819 women initiating ANC in their first trimester) were selected from ANC registries from 2010 to 2012...
2017: PloS One
https://www.readbyqxmd.com/read/28203641/the-antecedents-of-women-s-external-locus-of-control-associations-with-characteristics-of-their-parents-and-their-early-childhood
#18
Jean Golding, Steven Gregory, Yasmin Iles-Caven, Stephen Nowicki
Locus of control (LOC) measures individuals' expectancies regarding their ability to affect what happens to them based on how they behave. The more they believe their behaviour has something to do with what happens to them the more internal they are. In contrast the more they perceive that what happens to them is beyond their control and determined by luck, fate, chance or powerful others the more external they are. Copious research findings suggest that external LOC (ELOC) is associated with many adverse personal, social, academic and health outcomes...
January 2017: Heliyon
https://www.readbyqxmd.com/read/28202783/evaluation-of-a-complex-healthcare-intervention-to-increase-smoking-cessation-in-pregnant-women-interrupted-time-series-analysis-with-economic-evaluation
#19
Ruth Bell, Svetlana V Glinianaia, Zelda van der Waal, Andrew Close, Eoin Moloney, Susan Jones, Vera Araújo-Soares, Sharon Hamilton, Eugene Mg Milne, Janet Shucksmith, Luke Vale, Martyn Willmore, Martin White, Steven Rushton
OBJECTIVES: To evaluate the effectiveness of a complex intervention to improve referral and treatment of pregnant smokers in routine practice, and to assess the incremental costs to the National Health Service (NHS) per additional woman quitting smoking. DESIGN: Interrupted time series analysis of routine data before and after introducing the intervention, within-study economic evaluation. SETTING: Eight acute NHS hospital trusts and 12 local authority areas in North East England...
February 15, 2017: Tobacco Control
https://www.readbyqxmd.com/read/28193227/evaluation-of-scaling-up-of-hpv-self-collection-offered-by-community-health-workers-at-home-visits-to-increase-screening-among-socially-vulnerable-under-screened-women-in-jujuy-province-argentina
#20
Silvina Arrossi, Melisa Paolino, Laura Thouyaret, Rosa Laudi, Alicia Campanera
BACKGROUND: Self-collection has been proposed as a strategy to increase cervical screening coverage among hard-to-reach women. However, evaluations of the implementation of this strategy on a large scale are scarce. This paper describes the process and measurement of the scaling-up of self-collection offered by community health workers during home visits as a strategy to reach under-screened women aged 30+ with public health coverage, defined as the target women. METHODS: We used an adaptation of the Health System Framework to analyze key drivers of scaling-up...
February 13, 2017: Implementation Science: IS
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