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https://www.readbyqxmd.com/read/29216523/use-of-synthetic-stimulants-and-hallucinogens-in-a-cohort-of-electronic-dance-music-festival-attendees
#1
Amanda L A Mohr, Melissa Friscia, Jillian K Yeakel, Barry K Logan
Novel psychoactive substances (NPS), often characterized as unregulated psychoactive compounds designed to circumvent existing legislation, have become mainstream on the illicit drug market. Because of their physical and mind-altering properties, NPS may be deliberately or inadvertently ingested at electronic dance music (EDM) festivals to enhance the attendees' appreciation of the music and overall experience. Their widespread use at EDM festivals have been well documented and several adverse events and fatalities associated with NPS ingestion have been reported in the United States...
November 21, 2017: Forensic Science International
https://www.readbyqxmd.com/read/29180549/family-physicians-perceived-prevalence-safety-and-screening-for-cigarettes-marijuana-and-electronic-nicotine-delivery-systems-ends-use-during-pregnancy
#2
Thomas F Northrup, Michelle R Klawans, Yolanda R Villarreal, Adi Abramovici, Melissa A Suter, Joan M Mastrobattista, Carlos A Moreno, Kjersti M Aagaard, Angela L Stotts
OBJECTIVE: Assess perceptions of prevalence, safety, and screening practices for cigarettes and secondhand smoke exposure (SHSe), marijuana (and synthetic marijuana), electronic nicotine delivery systems (ENDS; eg, e-cigarettes), nicotine-replacement therapy (NRT), and smoking-cessation medications during pregnancy, among primary care physicians (PCPs) providing obstetric care. METHODS: A web-based, cross-sectional survey was e-mailed to 3750 US physicians (belonging to organizations within the Council of Academic Family Medicine Educational Research Alliance)...
November 2017: Journal of the American Board of Family Medicine: JABFM
https://www.readbyqxmd.com/read/29180537/a-cross-sectional-study-examining-associations-between-substance-use-frequency-problematic-use-and-stis-among-youth-living-with-hiv
#3
Kristi E Gamarel, Sharon Nichols, Christopher W Kahler, Andrew O Westfall, Michelle A Lally, Craig M Wilson
OBJECTIVES: This study sought to examine the prevalence of STIs and whether substance use frequency and/or problematic use-specifically alcohol, marijuana and other drugs-was associated with having an STI diagnosis among youth living with HIV (YLWH) METHODS: A sample of 823 YLWH were recruited at 14 adolescent HIV clinics through the Adolescent Medicine Trials Network for HIV Interventions. Study staff abstracted STI data from medical records for up to 26 weeks prior to participants' completing a cross-sectional survey including the ASSIST (Alcohol, Smoking and Substance Involvement Screening Test), which measures substance use frequency and consequences...
November 27, 2017: Sexually Transmitted Infections
https://www.readbyqxmd.com/read/29178487/therapeutic-benefit-of-smoked-cannabis-in-randomized-placebo-controlled-studies
#4
Lynneice L Bowen, Aimee L McRae-Clark
The medicinal use of marijuana has been legalized in 28 states, with a wide range of specificity for approved medical conditions. Even with the emergence of non-combustion-based delivery systems, in 2014, 90% of marijuana users used smoked marijuana. The purpose of this review is to summarize the data available on use of smoked marijuana for medical purposes. A literature search was performed to retrieve randomized controlled trials exploring the efficacy of smoked cannabis for treatment of a medical condition...
November 27, 2017: Pharmacotherapy
https://www.readbyqxmd.com/read/29154062/survey-of-complementary-and-alternative-medicine-in-pediatric-inpatient-settings
#5
Sam Stubblefield
OBJECTIVES: While use of complementary and alternative medicine (CAM) is common in children, we know little about its use for hospitalized children. This survey measured the rate of CAM use, specific modalities used, and policies related to CAM use for hospitalized children. DESIGN: Anonymous survey of hospitals in the Pediatric Research in Inpatient Settings (PRĪS) network SETTING: Hospitals in the PRĪS network. MAIN OUTCOME MEASURES: Rate of overall and specific CAM modality use, including whether these modalities are provided, permitted, or prohibited, and presence of a written policy on CAM use...
December 2017: Complementary Therapies in Medicine
https://www.readbyqxmd.com/read/29151103/immunoregulatory-role-of-cannabinoids-during-infectious-disease
#6
Rosalía Hernández-Cervantes, Mónica Méndez-Díaz, Óscar Prospéro-García, Jorge Morales-Montor
Although the endocannabinoid system (ECS) is involved in the regulation of several physiological processes, including sleep and the immune response, its role during infections has not been fully studied. It is well known that the use of this drug increases susceptibility to infections because of the impact on the modulation of the immune system. Concerning the medicinal or recreational use of marijuana, its influence on the course of an infection, whether this has been caused by bacteria, viruses, parasites, and to a lesser degree, fungi, has been reported...
November 18, 2017: Neuroimmunomodulation
https://www.readbyqxmd.com/read/29092791/editorial-for-the-special-issue-on-behavior-change-health-and-health-disparities-2017
#7
EDITORIAL
Stephen T Higgins
This Special Issue of Preventive Medicine (PM) is the 4th in a series on behavior change, health, and health disparities, a topic of critical importance to improving U.S. population health. The U.S. ranks near the bottom on measures of population health relative to other industrialized countries despite spending orders of magnitude more on health care than any other nation. Population health experts agree that the area of personal behavior, or lifestyle, such as substance abuse, physical inactivity/obesity, and non-adherence with medical regimens is the single largest contributor to this situation...
October 29, 2017: Preventive Medicine
https://www.readbyqxmd.com/read/29072720/cannabis-through-the-looking-glass-chemo-and-enantio-selective-separation-of-phytocannabinoids-by-enantioselective-ultra-high-performance-supercritical-fluid-chromatography
#8
G Mazzoccanti, O H Ismail, I D'Acquarica, C Villani, C Manzo, M Wilcox, A Cavazzini, F Gasparrini
By using the Inverted Chirality Columns Approach (ICCA) we have developed an enantioselective UHPSFC method to determine the enantiomeric excess (ee) of (-)-Δ9-THC in medicinal marijuana (Bedrocan®). The ee was high (99.73%), but the concentration of the (+)-enantiomer (0.135%) was not negligible, and it is worth a systematic evaluation of bioactivity.
November 14, 2017: Chemical Communications: Chem Comm
https://www.readbyqxmd.com/read/29056081/the-risks-and-benefits-of-cannabis-in-the-dermatology-clinic
#9
Gurbir Dhadwal, Mark G Kirchhof
Cannabis ( Cannabis sativa/indica), also known as marijuana, has been used for medicinal and recreational purposes for millennia. There has been a recent trend to legalize the use of cannabis, as illustrated by the recent legalization votes in numerous states in the United States and legislation in Canada to allow recreational cannabis use. With this increasing consumption of cannabis, dermatologists will see increased pressure to prescribe cannabis and will see the side effects of cannabis use with greater frequency...
October 1, 2017: Journal of Cutaneous Medicine and Surgery
https://www.readbyqxmd.com/read/28991884/hiv-continuum-of-care-for-youth-in-the-united-states
#10
Michelle A Lally, Jacob J van den Berg, Andrew O Westfall, Bret J Rudy, Sybil G Hosek, J Dennis Fortenberry, Dina Monte, Mary R Tanney, Elizabeth J McFarland, Jiahong Xu, Bill G Kapogiannis, Craig M Wilson
BACKGROUND: Beneficial HIV treatment outcomes require success at multiple steps along the HIV Continuum of Care. Youth living with HIV are a key population, and sites in the Adolescent Medicine Trials Network for HIV/AIDS Interventions (ATN) are known for modeling optimum HIV adolescent care. METHODS: A longitudinal cohort study conducted at 14 network sites across the United States assessed how the later steps of the Continuum of Care were achieved among youth: engagement, treatment and viral load suppression...
October 4, 2017: Journal of Acquired Immune Deficiency Syndromes: JAIDS
https://www.readbyqxmd.com/read/28975065/vanishing-lung-syndrome-compound-effect-of-tobacco-and-marijuana-use-on-the-development-of-bullous-lung-disease-a-joint-effort
#11
Shimshon Wiesel, Faraz Siddiqui, Tahir Khan, Sami Hossri, Dany El-Sayegh
Marijuana use has been increasing across the United States due to its legalization as both a medicinal and recreational product. A small number of case reports have described a pathological entity called vanishing lung syndrome (VLS), which is a rare bullous lung disease usually caused by tobacco smoking. Recent case reports have implicated marijuana in the development of VLS. We present a case of a 47-year-old man, who presented to our hospital with shortness of breath, fevers and a productive cough. On physical exam, he was tachypneic with audible stridor and absent right sided breath sounds...
July 31, 2017: Curēus
https://www.readbyqxmd.com/read/28937574/committee-opinion-no-722-marijuana-use-during-pregnancy-and-lactation
#12
(no author information available yet)
Cannabis sativa (marijuana) is the illicit drug most commonly used during pregnancy. The self-reported prevalence of marijuana use during pregnancy ranges from 2% to 5% in most studies. A growing number of states are legalizing marijuana for medicinal or recreational purposes, and its use by pregnant women could increase even further as a result. Because of concerns regarding impaired neurodevelopment, as well as maternal and fetal exposure to the adverse effects of smoking, women who are pregnant or contemplating pregnancy should be encouraged to discontinue marijuana use...
October 2017: Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28937569/committee-opinion-summary-no-722-marijuana-use-during-pregnancy-and-lactation
#13
(no author information available yet)
Cannabis sativa (marijuana) is the illicit drug most commonly used during pregnancy. The self-reported prevalence of marijuana use during pregnancy ranges from 2% to 5% in most studies. A growing number of states are legalizing marijuana for medicinal or recreational purposes, and its use by pregnant women could increase even further as a result. Because of concerns regarding impaired neurodevelopment, as well as maternal and fetal exposure to the adverse effects of smoking, women who are pregnant or contemplating pregnancy should be encouraged to discontinue marijuana use...
October 2017: Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28918484/drug-herb-interactions-in-the-elderly-patient-with-ibd-a-growing-concern
#14
REVIEW
Haider Rahman, Marina Kim, Galen Leung, Jesse A Green, Seymour Katz
Inflammatory bowel disease (IBD), which includes conditions such as Crohn's disease and ulcerative colitis, is becoming more prevalent with the elderly being the fastest growing group. Parallel to this, there is an increasing interest in the use of complementary and alternative medicine (CAM). Nearly half of patients with IBD have used CAM at one time. The elderly patients, however, are burdened by comorbid conditions, polypharmacy, and altered functional status. With increasing use of complementary and alternative medicine in our elderly patients with IBD, it is vital for the provider to provide counsel on drug-herb potential interactions...
December 2017: Current Treatment Options in Gastroenterology
https://www.readbyqxmd.com/read/28905873/cardiovascular-effects-of-marijuana-and-synthetic-cannabinoids-the-good-the-bad-and-the-ugly
#15
REVIEW
Pal Pacher, Sabine Steffens, György Haskó, Thomas H Schindler, George Kunos
Dysregulation of the endogenous lipid mediators endocannabinoids and their G-protein-coupled cannabinoid receptors 1 and 2 (CB1R and CB2R) has been implicated in a variety of cardiovascular pathologies. Activation of CB1R facilitates the development of cardiometabolic disease, whereas activation of CB2R (expressed primarily in immune cells) exerts anti-inflammatory effects. The psychoactive constituent of marijuana, Δ(9)-tetrahydrocannabinol (THC), is an agonist of both CB1R and CB2R, and exerts its psychoactive and adverse cardiovascular effects through the activation of CB1R in the central nervous and cardiovascular systems...
September 14, 2017: Nature Reviews. Cardiology
https://www.readbyqxmd.com/read/28898302/-belief-system-regarding-cannabis-its-use-and-consequences-users-versus-non-users-in-colombian-university-students
#16
Gonzalo Galván, Álvaro Sánchez-Carballo, Ileana Gómez-Morales, Oscar Humánez-Julio, Manuel Guerrero-Martelo, Francisco Vásquez De la Hoz
Descriptive and comparative study of cross-sectional that had as objective to evaluate and compare the beliefs about cannabis, its use and potential consequences between two groups of Colombian university students, matched by gender and age. The frst group consisted of ordinary consumers of cannabis (n=35) the second group consisted of students that have never tried cannabis (n=35). The results showed that the group of consumers presents a moderate risk of abuse and only the 20% fulflled dependence criteria...
November 2016: Vertex: Revista Argentina de Psiquiatriá
https://www.readbyqxmd.com/read/28875990/clinical-and-pre-clinical-evidence-for-functional-interactions-of-cannabidiol-and-%C3%AE-9-tetrahydrocannabinol
#17
Douglas L Boggs, Jacques D Nguyen, Daralyn Morgenson, Michael A Taffe, Mohini Ranganathan
The plant Cannabis sativa, commonly called cannabis or marijuana, has been used for its psychotropic and mind-altering side effects for millennia. There has been growing attention in recent years on its potential therapeutic efficacy as municipalities and legislative bodies in the United States, Canada, and other countries grapple with enacting policy to facilitate the use of cannabis or its constituents for medical purposes. There are over 550 chemical compounds and over 100 phytocannabinoids isolated from cannabis, including Δ(9)-tetrahydrocannabinol (THC) and Cannabidiol (CBD)...
September 6, 2017: Neuropsychopharmacology: Official Publication of the American College of Neuropsychopharmacology
https://www.readbyqxmd.com/read/28867414/is-the-practice-of-yoga-or-meditation-associated-with-a-healthy-lifestyle-results-of-a-national-cross-sectional-survey-of-28-695-australian-women
#18
Holger Cramer, David Sibbritt, Crystal L Park, Jon Adams, Romy Lauche
OBJECTIVES: To examine the relationship between yoga/meditation practice and health behavior in Australian women. METHODS: Women aged 19-25years, 31-36years, and 62-67years from the Australian Longitudinal Study on Women's Health (ALSWH) were surveyed regarding smoking, alcohol or drug use, physical activity and dietary behavior; and whether they practiced yoga/meditation on a regular basis. Associations of health behaviors with yoga/meditation practice were analyzed using multiple logistic regression modelling...
October 2017: Journal of Psychosomatic Research
https://www.readbyqxmd.com/read/28865255/parent-use-of-cannabis-for-intractable-pediatric-epilepsy-everyday-empiricism-and-the-boundaries-of-scientific-medicine
#19
Elisa J Sobo
Cannabis is an increasingly sought-after remedy for US children with intractable (biomedically uncontrollable) epilepsy. However, like other complementary-alternative medicine (CAM) modalities, and particularly as a federally illegal, stigmatized substance, it is unsanctioned by mainstream medicine. Parents are largely on their own when it comes to learning about, procuring, dispensing, and monitoring treatments. Exploring how they manage is crucial to better assist them. Moreover, it can illuminate how 'research' done on the ground by laypeople variously disrupts and reinforces lay-expert and science-non-science divides...
August 5, 2017: Social Science & Medicine
https://www.readbyqxmd.com/read/28846058/intercorrelation-of-alcohol-and-other-drug-use-disorders-among-a-national-sample-of-drivers
#20
Michael Scherer, Sarah Canham, Robert B Voas, C Debra Furr-Holden
This study examined the relationship between alcohol, marijuana, cocaine, and painkiller use disorders in a sample of drivers. We studied nighttime drivers aged 16 to 87 (n = 4,277) from the 2007 National Roadside Survey who reported substance use behaviors and provided breath tests for alcohol. Logistic regression analyses assessed the relationships between (1) substance (i.e., alcohol/marijuana/cocaine/pain killer) use disorders; (2) demographic characteristics; and (3) BAC levels. Overall, 13.2% of participants met criteria for marijuana use disorder, 7% met criteria for cocaine use disorder, and 15...
August 28, 2017: Journal of Psychoactive Drugs
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