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https://www.readbyqxmd.com/read/27911134/split-face-histological-and-biochemical-evaluation-of-tightening-efficacy-using-temperature-and-impedance-controlled-continuous-non-invasive-radiofrequency-energy
#1
Sylvie Boisnic, Marc Divaris, Marie-Christine Branchet, Andrew Anthony Nelson
BACKGROUND: Bi-polar radiofrequency (RF) is capable of heating dermal collagen fibers and inducing skin tightening by collagen remodelling. OBJECTIVE: To substantiate safety and improvement of skin laxity following skin heating with a novel temperature and impedance controlled non-invasive radiofrequency (RF) device by histological and biochemical evaluations. METHODS: A split-face study was performed on 4 subjects that underwent 8 weekly RF sessions on one side of their face, leaving the other side an untreated control and then underwent face-lift procedure...
December 2, 2016: Journal of Cosmetic and Laser Therapy: Official Publication of the European Society for Laser Dermatology
https://www.readbyqxmd.com/read/27871801/lipid-profiling-of-polarized-human-monocyte-derived-macrophages
#2
J Rafael Montenegro-Burke, Jessica A Sutton, Lisa M Rogers, Ginger L Milne, John A McLean, David M Aronoff
The highly orchestrated transcriptional and metabolic reprogramming during activation drastically transforms the main functions and physiology of human macrophages across the polarization spectrum. Lipids, for example, can modify protein function by acting remotely as signaling molecules but also locally by altering the physical properties of cellular membranes. These changes play key roles in the functions of highly plastic immune cells due to their involvement in inflammation, immune responses, phagocytosis and wound healing processes...
November 15, 2016: Prostaglandins & Other Lipid Mediators
https://www.readbyqxmd.com/read/27846563/observation-of-a-nematic-quantum-hall-liquid-on-the-surface-of-bismuth
#3
Benjamin E Feldman, Mallika T Randeria, András Gyenis, Fengcheng Wu, Huiwen Ji, R J Cava, Allan H MacDonald, Ali Yazdani
Nematic quantum fluids with wave functions that break the underlying crystalline symmetry can form in interacting electronic systems. We examined the quantum Hall states that arise in high magnetic fields from anisotropic hole pockets on the Bi(111) surface. Spectroscopy performed with a scanning tunneling microscope showed that a combination of single-particle effects and many-body Coulomb interactions lift the six-fold Landau level (LL) degeneracy to form three valley-polarized quantum Hall states. We imaged the resulting anisotropic LL wave functions and found that they have a different orientation for each broken-symmetry state...
October 21, 2016: Science
https://www.readbyqxmd.com/read/27837282/the-chromosomal-basis-of-meiotic-acentrosomal-spindle-assembly-and-function-in-oocytes
#4
REVIEW
Sarah J Radford, Alexandra L Nguyen, Karen Schindler, Kim S McKim
Several aspects of meiosis are impacted by the absence of centrosomes in oocytes. Here, we review four aspects of meiosis I that are significantly affected by the absence of centrosomes in oocyte spindles. One, microtubules tend to assemble around the chromosomes. Two, the organization of these microtubules into a bipolar spindle is directed by the chromosomes. Three, chromosome bi-orientation and attachment to microtubules from the correct pole require modification of the mechanisms used in mitotic cells. Four, chromosome movement to the poles at anaphase cannot rely on polar anchoring of spindle microtubules by centrosomes...
November 11, 2016: Chromosoma
https://www.readbyqxmd.com/read/27828441/concept-of-active-parallax-barrier-on-polarizing-interlayer-for-near-viewing-autostereoscopic-displays
#5
Se-Um Kim, Jiyoon Kim, Jeng-Hun Suh, Jun-Hee Na, Sin-Doo Lee
We proposed a concept of an active parallax barrier using a liquid crystal-on-polarizing interlayer (LPI) for near-viewing autostereoscopic displays. In contrast to a conventional two-panel configuration where two independent panels are stacked together for displaying and parallaxing purposes, a monolithic one-panel architecture was demonstrated with the help of the LPI. The LPI was constructed using a polarizer sheet, one side of which provided the support for the active parallax barrier and the other served as the substrate for the image panel...
October 31, 2016: Optics Express
https://www.readbyqxmd.com/read/27814360/mutation-in-lim2-is-responsible-for-autosomal-recessive-congenital-cataracts
#6
Bushra Irum, Shahid Y Khan, Muhammad Ali, Haiba Kaul, Firoz Kabir, Bushra Rauf, Fareeha Fatima, Raheela Nadeem, Arif O Khan, Saif Al Obaisi, Muhammad Asif Naeem, Idrees A Nasir, Shaheen N Khan, Tayyab Husnain, Sheikh Riazuddin, Javed Akram, Allen O Eghrari, S Amer Riazuddin
PURPOSE: To identify the molecular basis of non-syndromic autosomal recessive congenital cataracts (arCC) in a consanguineous family. METHODS: All family members participating in the study received a comprehensive ophthalmic examination to determine their ocular phenotype and contributed a blood sample, from which genomic DNA was extracted. Available medical records and interviews with the family were used to compile the medical history of the family. The symptomatic history of the individuals exhibiting cataracts was confirmed by slit-lamp biomicroscopy...
2016: PloS One
https://www.readbyqxmd.com/read/27813026/research-on-design-of-tri-color-shift-device
#7
Ping Xu, Xia Yuan, Haixuan Huang, Tuo Yang, Yanyan Huang, Tengfei Zhu, Shaotuo Tang, Wenda Peng
An azimuth-tuned tri-color shift device based on an embedded subwavelength one-dimensional rectangular structure with single period is proposed. High reflection efficiencies for both TE and TM polarizations can be achieved simultaneously. Under an oblique incidence of 60°, the reflection efficiencies can reach up to 85, 86, and 100 % in blue (azimuth of 24°), green (azimuth of 63°), and red (azimuth of 90°) waveband, respectively. Furthermore, the laws of influence of device period, groove depth, coating thickness, and incident angle on reflection characteristics are investigated and exposed, and feasibility of the device is demonstrated...
December 2016: Nanoscale Research Letters
https://www.readbyqxmd.com/read/27805306/spectroscopic-and-in-silico-study-of-binding-mechanism-of-cynidine-3-o-glucoside-with-human-serum-albumin-and-glycated-human-serum-albumin
#8
Xin Gao, Hongna Bi, Jingjing Jia, Lin Tang
The drug-serum albumin interaction plays a dominant role in drug efficacy and disposition. The glycation of serum albumin that occurs during diabetes may affect its drug-binding properties in vivo. In order to evaluate the interactivity characteristics of cyanidin-3-O-glucoside (C3G) with human serum albumin (HSA) and glycated human serum albumin (gHSA), this study was undertaken using multiple spectroscopic techniques and molecular modeling analysis. Time-resolved fluorescence and the thermodynamic parameters indicated that the quenching mechanism was static quenching, and hydrogen bonding and Van der Waals force were the main forces...
November 2, 2016: Luminescence: the Journal of Biological and Chemical Luminescence
https://www.readbyqxmd.com/read/27803947/an-efficient-visible-light-photocatalyst-made-from-a-nonpolar-layered-semiconductor-by-grafting-electron-withdrawing-organic-molecules-to-its-surface
#9
Benyan Xu, Yang An, Yuanyuan Liu, Baibiao Huang, Xiaoyan Qin, Xiaoyang Zhang, Ying Dai, Myung-Hwan Whangbo
A nonpolar inorganic layered semiconductor becomes an efficient visible-light photocatalyst when its surface layer becomes polar by chemically attaching electron-withdrawing 4-substituted thiophenolates (-)S-C6H4Z (Z = NO2, COOH, Cl, Br, H, CH3, NH2) via Bi-S bonds. An in-depth study finds a correlation between the apparent rate constant (kapp) and the Hammett constants σpara of the 4-substituted groups.
November 2, 2016: Chemical Communications: Chem Comm
https://www.readbyqxmd.com/read/27787242/high-pressure-seebeck-coefficients-and-thermoelectric-behaviors-of-bi-and-pbte-measured-using-a-paris-edinburgh-cell
#10
Jason Baker, Ravhi Kumar, Changyong Park, Curtis Kenney-Benson, Andrew Cornelius, Nenad Velisavljevic
A new sample cell assembly design for the Paris-Edinburgh type large-volume press for simultaneous measurements of X-ray diffraction, electrical resistance, Seebeck coefficient and relative changes in the thermal conductance at high pressures has been developed. The feasibility of performing in situ measurements of the Seebeck coefficient and thermal measurements is demonstrated by observing well known solid-solid phase transitions of bismuth (Bi) up to 3 GPa and 450 K. A reversible polarity flip has been observed in the Seebeck coefficient across the Bi-I to Bi-II phase boundary...
November 1, 2016: Journal of Synchrotron Radiation
https://www.readbyqxmd.com/read/27782637/polarity-formation-in-crystals-with-long-range-molecular-interactions-a-monte-carlo-study
#11
Luigi Cannavacciuolo, Jürg Hulliger
Stochastic formation of a bi-polar state in three dimensional arrays of polar molecules with full Coulomb interactions is reproduced by Monte Carlo simulation. The size of the system is comparable to that of a real crystal seed. The spatial decay of the average order parameter is significantly slowed down by the long range interactions and the exact representation of correlation effects in terms of a single characteristic length becomes impossible. Finite size effects and possible scale invariance symmetry of the order parameter are extensively discussed...
September 28, 2016: Journal of Chemical Physics
https://www.readbyqxmd.com/read/27709267/timap-repression-by-tgf%C3%AE-and-hdac3-associated-smad-signaling-regulates-macrophage-m2-phenotypic-phagocytosis
#12
Jun Yang, Shasha Yin, Fangfang Bi, Lin Liu, Tian Qin, Hongwei Wang, Wangsen Cao
: TIMAP (TGFβ-inhibited membrane-associated protein) is an endothelium-enriched TGFβ downstream protein and structurally belongs to the targeting subunit of myosin phosphatase; however, the mechanism of TGFβ repressing TIMAP and its functional relevance to TGFβ bioactivity remain largely unknown. Here, we report that TIMAP is reduced in TGFβ-elevated mouse fibrotic kidney and highly expressed in macrophages. TGFβ repression of TIMAP is associated with HDAC3 upregulation and its recruitment by Smad2/3 at the Smad binding element on TIMAP promoter, whereas specific HDAC3 inhibition reversed the TIMAP repression, suggesting that TGFβ transcriptionally downregulates TIMAP through HDAC3-associated Smad signaling...
October 6, 2016: Journal of Molecular Medicine: Official Organ of the "Gesellschaft Deutscher Naturforscher und Ärzte"
https://www.readbyqxmd.com/read/27707795/a-new-mode-of-mitochondrial-transport-and-polarized-sorting-regulated-by-dynein-milton-and-miro
#13
Anna Melkov, Raju Baskar, Yehonatan Alcalay, Uri Abdu
Intrinsic cell microtubule (MT) polarity, together with molecular motors and adaptor proteins, determines mitochondrial polarized targeting and MT-dependent transport. In polarized cells, such as neurons, mitochondrial mobility and transport require the regulation of kinesin and dynein by two adaptor proteins, Milton and Miro. Recently, we found that dynein heavy chain 64C (Dhc64C) is the primary motor protein for both anterograde and retrograde transport of mitochondria in the Drosophila bristle. In this study, we show that a molecular lesion in the Dhc64C allele that reduced bristle mitochondrial velocity generated a variant that acts as a 'slow' dynein in an MT-gliding assay, indicating that dynein directly regulates mitochondrial transport...
November 15, 2016: Development
https://www.readbyqxmd.com/read/27673564/mir-181a-induces-macrophage-polarized-to-m2-phenotype-and-promotes-m2-macrophage-mediated-tumor-cell-metastasis-by-targeting-klf6-and-c-ebp%C3%AE
#14
Jia Bi, Xianxin Zeng, Lin Zhao, Qian Wei, Lifeng Yu, Xinnan Wang, Zhaojin Yu, Yaming Cao, Fengping Shan, Minjie Wei
Macrophages can acquire a variety of polarization status and functions: classically activated macrophages (M1 macrophages); alternatively activated macrophages (M2 macrophages). However, the molecular basis of the process is still unclear. Here, this study addresses that microRNA-181a (miR-181a) is a key molecule controlling macrophage polarization. We found that miR-181a is overexpressed in M2 macrophages than in M1 macrophages. miR-181a expression was decreased when M2 phenotype converted to M1, whereas it increased when M1 phenotype converted to M2...
2016: Molecular Therapy. Nucleic Acids
https://www.readbyqxmd.com/read/27661388/the-effect-of-chemical-variations-on-the-structural-polarity-of-relaxor-ferroelectrics-studied-by-resonance-raman-spectroscopy
#15
A Rohrbeck, G de la Flor, M I Aroyo, M Gospodinov, U Bismayer, B Mihailova
Resonance Raman spectroscopy was applied to doped PbSc0.5Ta0.5O3 and PbSc0.5Nb0.5O3 relaxor ferroelectrics, to better understand the effect of composition disorder on the mesoscopic-scale polar order in complex perovskite-type (ABO3) ferroelectrics. The excitation photon energy used was 3.8 eV, which is slightly above the energy gap and corresponds to the maximum of the optical dielectric permittivity. Group-theory analysis reveals that the resonance Raman scattering (RRS) observed under these conditions is allowed only in polar crystal classes...
November 30, 2016: Journal of Physics. Condensed Matter: An Institute of Physics Journal
https://www.readbyqxmd.com/read/27659542/assessing-size-and-strength-of-the-clavicle-for-its-usefulness-for-sex-estimation-in-a-british-medieval-sample
#16
Thomas Atterton, Isabelle De Groote, Constantine Eliopoulos
The construction of the biological profile from human skeletal remains is the foundation of anthropological examination. However, remains may be fragmentary and the elements usually employed, such as the pelvis and skull, are not available. The clavicle has been successfully used for sex estimation in samples from Iran and Greece. In the present study, the aim was to test the suitability of the measurements used in those previous studies on a British Medieval population. In addition, the project tested whether discrimination between sexes was due to size or clavicular strength...
October 2016: Homo: Internationale Zeitschrift Für die Vergleichende Forschung Am Menschen
https://www.readbyqxmd.com/read/27638736/isospora-cardellinae-n-sp-apicomplexa-eimeriidae-from-the-red-warbler-cardellina-rubra-swainson-passeriformes-parulidae-in-mexico
#17
Celene Salgado-Miranda, Juan Pablo Medina, Andrea Paloma Zepeda-Velázquez, Michele García-Conejo, Karla Patricia Galindo-Sánchez, Mariusz Krzysztof Janczur, Edgardo Soriano-Vargas
A new coccidian species (Protozoa: Apicomplexa: Eimeriidae) collected from the red warbler Cardellina rubra (Swainson) is reported from the Nevado de Toluca National Park, Mexico. Isospora cardellinae n. sp. has subspherical oöcysts, measuring on average 26.6 × 25.4 μm, with smooth, bi-layered wall, c.1.3 μm thick. Micropyle, oöcyst residuum, and polar granule are absent. Sporocysts are ovoidal, measuring on average 19.0 × 12.0 µm, with a knob-like Stieda body, a trapezoidal sub-Stieda body and sporocyst residuum composed of scattered spherules of different sizes...
October 2016: Systematic Parasitology
https://www.readbyqxmd.com/read/27638735/two-new-species-of-coccidia-apicomplexa-eimeriidae-from-leaf-tailed-geckos-uroplatus-spp-sauria-gekkonidae-from-madagascar-including-a-new-host-of-eimeria-brygooi-upton-barnard-1987
#18
Chris T McAllister, R Scott Seville, Ruston Hartdegen
During May and June 2015, four common leaf-tailed geckos, Uroplatus fimbriatus (Schneider), five satanic leaf-tailed geckos, Uroplatus phantasticus (Boulenger), and four mossy leaf-tailed geckos, Uroplatus sikorae Boettger originally collected from Madagascar and housed at the Dallas Zoo, USA, had their faeces examined for coccidian parasites. Eight (62%) geckos were found to be passing oöcysts, including a new eimerian, a new isosporan and a previously described eimerian. Three of four (75%) U. fimbratus (type-host) and one of five (20%) U...
October 2016: Systematic Parasitology
https://www.readbyqxmd.com/read/27631595/giant-polarization-and-high-temperature-monoclinic-phase-in-a-lead-free-perovskite-of-bi-zn0-5ti0-5-o3-bifeo3
#19
Zhao Pan, Jun Chen, Runze Yu, Hajime Yamamoto, Yangchun Rong, Lei Hu, Qiang Li, Kun Lin, Li You, Kun Zhao, Longlong Fan, Yang Ren, Kenichi Kato, Masaki Azuma, Xianran Xing
Lead-free piezoelectrics have attracted increasing attention because of the awareness of lead toxicity to the environment. Here, a new bismuth-based lead-free perovskite, (1 - x)Bi(Zn0.5Ti0.5)O3-xBiFeO3, has been synthesized via a high-pressure and high-temperature method. It exhibits interesting properties of giant polarization, morphotropic phase boundary (MPB), and monoclinic phase. In particular, large tetragonality (c/a = 1.228) and giant spontaneous polarization of 110 μC/cm(2) has been obtained in 0...
October 3, 2016: Inorganic Chemistry
https://www.readbyqxmd.com/read/27626290/polar-nature-of-ch3nh3-3bi2i9-perovskite-like-hybrids
#20
Machteld E Kamminga, Alessandro Stroppa, Silvia Picozzi, Mikhail Chislov, Irina A Zvereva, Jacob Baas, Auke Meetsma, Graeme R Blake, Thomas T M Palstra
High-quality single crystals of perovskite-like (CH3NH3)3Bi2I9 hybrids have been synthesized, using a layered-solution crystal-growth technique. The large dielectric constant is strongly affected by the polar ordering of its constituents. Progressive dipolar ordering of the methylammonium cation upon cooling below 300 K gradually converts the hexagonal structure (space group P63/mmc) into a monoclinic phase (C2/c) at 160 K. A well-pronounced, ferrielectric phase transition at 143 K is governed by in-plane ordering of the bismuth lone pair that breaks inversion symmetry and results in a polar phase (space group P21)...
September 14, 2016: Inorganic Chemistry
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