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Bi polar

Ashutosh Kumar Verma, Sunita Singh Dhawan
Background: Gymnema sylvestre R. Br. a member of family Asclepiadaceae as mentioned in Indian Pharmacopoeia popular among the researchers because of stimulatory effect of its phytoconstituent on pancreatic cells and potential to treat Type I and II type of diabetes. Objectives: Development of cost-effective marker system for the selection of high gymnemic acid yielding accessions of G. sylvestre. Materials and Methods: Presoaked seeds of Brassica campestris treated with different dilutions of gymnemagenin and 10% leaf extract of twenty different accessions of G...
October 2017: Pharmacognosy Magazine
Jin Lee, Rui Liao, Gaowei Wang, Bi-Huei Yang, Xiaolin Luo, Nissi M Varki, Shuang-Jian Qiu, Bing Ren, Wenxian Fu, Gen-Sheng Feng
Liver cancer has become the second most deadly malignant disease, with no efficient targeted or immune therapeutic agents available yet. While dissecting the roles of cytoplasmic signaling molecules in hepatocarcinogenesis using an inducible mouse gene targeting system, Mx1-cre, we identified a potent liver tumor-inhibitory effect of synthetic double-stranded RNA (dsRNA), polyinosinic-polycytidylic acid (pIC), an inducer of the Mx1-cre system. Injection of pIC at the pre-cancer stage robustly suppressed liver tumorigenesis either induced by chemical carcinogens or by Pten loss and associated hepatosteatosis...
November 14, 2017: Cell Reports
Nickolai Zhavoronkov, Mikhail Ivanov
Attosecond (1  as=10(-18)  s) pulses produced through high harmonic generation (HHG) are a basis for studies of electron dynamics during light-matter interaction on an electron's natural time scale. Extensively exploited HHG technology has, however, a few unsolved problems, where producing of circularly polarized or chiral attosecond pulses belongs to them. We have demonstrated experimentally a way to control the ellipticity of attosecond pulse trains produced via HHG in two-color, bi-circular laser fields...
November 15, 2017: Optics Letters
Ming Liu, Zheng Zhang, Leesa Sampson, Xuan Zhou, Kodandaramireddy Nalapareddy, Yuxin Feng, Shailaja Akunuru, Jaime Melendez, Ashley Kuenzi Davis, Feng Bi, Hartmut Geiger, Mei Xin, Yi Zheng
RHOA, a founding member of the Rho GTPase family, is critical for actomyosin dynamics, polarity, and morphogenesis in response to developmental cues, mechanical stress, and inflammation. In murine small intestinal epithelium, inducible RHOA deletion causes a loss of epithelial polarity, with disrupted villi and crypt organization. In the intestinal crypts, RHOA deficiency results in reduced cell proliferation, increased apoptosis, and a loss of intestinal stem cells (ISCs) that mimic effects of radiation damage...
November 6, 2017: Stem Cell Reports
K Sumida, Y Ishida, S Zhu, M Ye, A Pertsova, C Triola, K A Kokh, O E Tereshchenko, A V Balatsky, S Shin, A Kimura
Topological insulators (TIs) possess spin-polarized Dirac fermions on their surface but their unique properties are often masked by residual carriers in the bulk. Recently, (Sb1-x Bi x )2Te3 was introduced as a non-metallic TI whose carrier type can be tuned from n to p across the charge neutrality point. By using time- and angle-resolved photoemission spectroscopy, we investigate the ultrafast carrier dynamics in the series of (Sb1-x Bi x )2Te3. The Dirac electronic recovery of ∼10 ps at most in the bulk-metallic regime elongated to >400 ps when the charge neutrality point was approached...
October 26, 2017: Scientific Reports
Werner Badenhorst, Tania Hanekom, Johan J Hanekom
The study presents the application of a purely conductance-based stochastic nerve fibre model to human auditory nerve fibres within finite element volume conduction models of a semi-generic head and user-specific cochleae. The stochastic, threshold and temporal characteristics of the human model are compared and successfully validated against physiological feline results with the application of a mono-polar, bi-phasic, cathodic first stimulus. Stochastic characteristics validated include: (i) the log(Relative Spread) versus log(fibre diameter) distribution for the discharge probability versus stimulus intensity plots and (ii) the required exponential membrane noise versus transmembrane voltage distribution...
October 24, 2017: Biological Cybernetics
Xiuxiu Han, Shencheng Fu, Xintong Zhang, Shuang Lu, Shuangyan Liu, Xinnong Wang, Ruiya Ji, Xiuli Wang, Yichun Liu, Jinhuan Li
Stable and controllable optical memory is necessary for the development of current information technology. In this context, Ag/TiO2 films have received much attention for their photosensitivity in wavelength and polarization, which can be applied to high-density optical storage. Here, we carried out dual-wavelength holographic recording using 403.4 nm and 532 nm lasers, and obtained mixed microfringes based on selective photodissolution of Ag nanoparticles of various sizes in TiO2 nanoporous films. Two recording methods of simultaneous and sequential multiplexing were investigated...
October 1, 2017: Applied Optics
Jing Luo, Dong Liu, Binyu Wang, Lei Bi, Kejun Zhang, Yuling Liu, Chunao Wen, Lingying Jiang, Liming Yang, Lin Su
A half-wave plate (HWP) is a critical component for calibrating the gain ratio in polarization lidars. In this paper, the effects of a nonideal HWP on the gain ratio calibration measurements are analyzed. We focus on the ±45° method and the multi-rotation HWP method, which are the two main approaches for calibrating the gain ratio. Specifically, we discuss the influences of a nonideal HWP from two scenarios: an HWP with nonideal polarization properties and an ideal HWP under nonideal external conditions. The allowable ranges of relevant parameters for the nonideal polarization properties of HWPs are obtained, which can help to determine qualified HWPs in polarization lidars...
October 10, 2017: Applied Optics
Guan-Kai Zhao, Wei Lin, Hong-Jie Chen, Yao-Kun Lv, Xiao-Mei Tan, Zhong-Min Yang, Valery M Mashinsky, Alexander Krylov, Ai-Ping Luo, Hu Cui, Zhi-Chao Luo, Wen-Cheng Xu, Evgeny M Dianov
We experimentally demonstrate the generation of dissipative soliton resonance (DSR) in a passively mode-locked Bi-doped fiber ring laser based on nonlinear polarization rotation (NPR) technique. The DSR with the central wavelength of 1169.5 nm has a repetition rate of 343.7 kHz. By purely increasing the pump power, the DSR evolves from Gaussian shape to rectangular shape with the duration extending from 2.1 ns to 13.1 ns, while keeping the pulse amplitude and the 3-dB spectrum bandwidth almost constant. The single-pulse energy reaches 24...
August 21, 2017: Optics Express
Álvaro Jiménez-Galán, Nickolai Zhavoronkov, Marcel Schloz, Felipe Morales, Misha Ivanov
The bi-circular scheme for high harmonic generation, which combines two counter-rotating circular fields with frequency ratio 2:1, has recently permitted to generate high harmonics with essentially circular polarization, opening the way for ultrafast chiral studies. This scheme produces harmonic lines at 3N + 1 and 3N + 2 multiples of the fundamental driving frequency, while the 3N lines are forbidden owing to the three-fold symmetry of the field. It is generally established that the routinely observed signals at these forbidden harmonic lines come from a slight ellipticity in the driving fields, which breaks the three-fold symmetry...
September 18, 2017: Optics Express
Fangyi Chen, Wanxi Zhang, Taiji Tian, Binglian Bai, Haitao Wang, Min Li
Intramolecular charge-transfer characteristics of a series symmetric methoxy -substituted bi-1,3,4-oxadiazole derivatives with various substituted positions and quantities have been studied with a combination of experimental techniques and theoretical calculations to investigate the substituent effect. Different degrees of fluorescence red shift in polar solvents are observed in these compounds. The meta-substituted molecule (BOXD-m-OCH3) exhibits a larger red shift (82 nm) than the other two monosubstituted molecules, BOXD-o-OCH3 (40 nm) and BOXD-p-OCH3 (37 nm); the polysubstituted molecules BOXD-D1 and BOXD-T1 show 80 and 104 nm red shifts, respectively, which are obviously larger than the monosubstituted molecules...
October 30, 2017: Journal of Physical Chemistry. A
Sami Saadi, Nazamid Saari, Abdulkarim Sabo Mohammed, Hasanah Mohd Ghazali, Farooq Anwar
Cell impurities are an emerging nucleating molecular barriers having the capability in disordering the metabolic chain reactions of proteolysis, glycolysis and lipolysis. Their massive effects induced by copolymer crystal growth in compaction with metal and mineral transients are extended as well as in damaging DNA and mRNA structure motif and other molecular assembly e.g. histones structure unites. Their polycrystalline packing modes, polydispersity and their tendency to surface and interface adhesion prompted us in structuring scaffold biomaterials enriched with biopeptides, layered by phospho-glycerides ester-forms...
October 11, 2017: Journal of Controlled Release: Official Journal of the Controlled Release Society
Long Zhou, Jianhong Dai, Yisheng Chai, Huimin Zhang, Shuai Dong, Huibo Cao, Stuart Calder, Yunyu Yin, Xiao Wang, Xudong Shen, Zhehong Liu, Takashi Saito, Yuichi Shimakawa, Hajime Hojo, Yuichi Ikuhara, Masaki Azuma, Zhiwei Hu, Young Sun, Changqing Jin, Youwen Long
Magnetoelectric multiferroics have received much attention in the past decade due to their interesting physics and promising multifunctional performance. For practical applications, simultaneous large ferroelectric polarization and strong magnetoelectric coupling are preferred. However, these two properties have not been found to be compatible in the single-phase multiferroic materials discovered as yet. Here, it is shown that superior multiferroic properties exist in the A-site ordered perovskite BiMn3 Cr4 O12 synthesized under high-pressure and high-temperature conditions...
October 9, 2017: Advanced Materials
Daitaro Kanno, Etsuo Tsuchikane, Kenya Nasu, Osamu Katoh, Yoshifumi Kashima, Umihiko Kaneko, Tsutomu Fujita, Yoriyasu Suzuki, Takahiko Suzuki
OBJECTIVES: To examine the safety, efficacy, and efficiency of the PlasmaWire(TM) System to recanalize coronary chronic total occlusions (CTO) using controlled ablation inside the CTO. BACKGROUND: The PlasmaWire(TM) System is a new bipolar radiofrequency (RF) wire system utilizing plasma-mediated ablation to facilitate wire crossing in CTOs. Two independent PlasmaWire(TM) wires are used in tandem for channel creation by applying RF energy between the tips so as to localize the ablation...
October 5, 2017: Catheterization and Cardiovascular Interventions
Alexandra Neagu, Cheuk-Wai Tai
Local structural distortions in Na0.5Bi0.5TiO3-based solid solutions have been proved to play a crucial role in understanding and tuning their enhanced piezoelectric properties near the morphotropic phase boundary. In this work all local structural disorders in a lead-free ternary system, namely 85%Na0.5Bi0.5TiO3-10%Bi0.5K0.5TiO3-5%BaTiO3, were mapped in reciprocal space by 3D electron diffraction. Furthermore, a comprehensive model of the local disorder was developed by analysing the intensity and morphology of the observed weak diffuse scattering...
October 2, 2017: Scientific Reports
Lingling Bi, Xupeng Gao, Lijing Zhang, Dejun Wang, Xiaoxin Zou, Tengfeng Xie
NiCoP has caused wide attention in the field of electrocatalysis, while there is little concern on photocatalysis study and its photocatalytic mechanism. Herein we reported a simple one-pot synthesis method of NiCoP/g-C3N4 as highly efficient photocatalyst for hydrogen production from water for the first time. Remarkably, the excellent photocatalytic activity is obtained for the 50 mg NiCoP/g-C3N4 (1643 molg-1h-1), which is 21 times higher than that of bare g-C3N4. The excellent performance is due to the synergistic effect of the improved separation efficiency and the effective charge transfer efficiency...
October 2, 2017: ChemSusChem
Adam Connolly, Matthew D Robson, Jürgen Schneider, Rebecca Burton, Gernot Plank, Martin J Bishop
Novel low-energy defibrillation therapies are thought to be driven by virtual-electrodes (VEs), due to the interaction of applied monophasic electric shocks with fine-scale anatomical structures within the heart. Significant inter-species differences in the cardiac (micro)-anatomy exist, however, particularly with respect to the degree of endocardial trabeculations, which may underlie important differences in response to low-energy defibrillation protocols. Understanding the interaction of monophasic electric fields with the specific human micro-anatomy is therefore imperative in facilitating the translation and optimisation of these promising experimental therapies to the clinic...
September 2017: Chaos
H Bentmann, H Maaß, E E Krasovskii, T R F Peixoto, C Seibel, M Leandersson, T Balasubramanian, F Reinert
A comprehensive understanding of spin-polarized photoemission is crucial for accessing the electronic structure of spin-orbit coupled materials. Yet, the impact of the final state in the photoemission process on the photoelectron spin has been difficult to assess in these systems. We present experiments for the spin-orbit split states in a Bi-Ag surface alloy showing that the alteration of the final state with energy may cause a complete reversal of the photoelectron spin polarization. We explain the effect on the basis of ab initio one-step photoemission theory and describe how it originates from linear dichroism in the angular distribution of photoelectrons...
September 8, 2017: Physical Review Letters
M Zhang, W Zhang, A Q Liu, F C Li, C F Lan
Polarization is an important property of electromagnetic (EM) wave and different polarization manipulations are required for varied optical applications. Here we report a reconfigurable metasurface which achieves both the polarization conversion and the polarization rotation in THz regime. The metasurface is reconfigured through the micro-electro-mechanical-systems (MEMS) actuation. The cross polarization transmittance from a linear polarized incidence is experimentally tuned from 0 to 28% at 2.66 THz. In addition, the polarization rotation angle is effectively changed from -12...
September 21, 2017: Scientific Reports
Mandar M Shirolkar, Jieni Li, Xiaolei Dong, Ming Li, Haiqian Wang
In recent years, BiFeO3 has attracted significant attention as an interesting multiferroic material in the exploration of fundamental science and development of novel applications. Our previous study (Phys. Chem. Chem. Phys.18, 2016, 25409) highlighted the interesting physicochemical features of BiFeO3 of sub-5 nm dimension. The study also accentuated the existence of weak ferroelectricity at sub-5 nm dimensions in BiFeO3. Based on this feature, we have prepared thin films using sub-5 nm BiFeO3 nanoparticles and explored various physicochemical properties of the thin film...
October 4, 2017: Physical Chemistry Chemical Physics: PCCP
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